EuRBPDB

Description

RBDs

Expression

Transcripts

Gene Model

Pathways

PPI

Paralogs

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000101888 (Gene tree)
Gene ID: 55916
Gene Symbol: NXT2
Alias: P15-2
Full Name: nuclear transport factor 2 like export factor 2
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Plus strand
Length: 8,918 bases
Position: chrX:109,535,781-109,544,698
Accession: 18151
RBP type: canonical RBP
Summary: The protein encoded by this gene contains a nuclear transport factor 2 (NTF2) domain, which plays an important role in the trafficking of macromolecules, ions, and small molecules between the cytoplasm and nucleus. This protein may also have a role in mRNA nuclear export. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jun 2011]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000361178	NTF2	PF02136.20	1e-30	1	1
ENSP00000218004	NTF2	PF02136.20	2.3e-30	1	1
ENSP00000361175	NTF2	PF02136.20	3.9e-25	1	1
ENSP00000361179	NTF2	PF02136.20	3.9e-25	1	1

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000218004	NXT2-201	2692	-	ENSP00000218004	197 (aa)	-	Q9NPJ8
ENST00000372103	NXT2-202	1085	XM_017029648	ENSP00000361175	114 (aa)	XP_016885137	Q9NPJ8
ENST00000372106	NXT2-203	2562	XM_011530989	ENSP00000361178	142 (aa)	XP_011529291	Q9NPJ8
ENST00000372107	NXT2-204	937	-	ENSP00000361179	114 (aa)	-	Q9NPJ8

Gene Model

Click here to download ENSG00000101888's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa03008	Ribosome biogenesis in eukaryotes	KEGG
hsa03013	RNA transport	KEGG
hsa03015	mRNA surveillance pathway	KEGG
hsa05164	Influenza A	KEGG

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000101888's network

* RBP PPI network refers to all genes directly bind to RBP

Paralogs

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy
ENSG00000101888	NXT2	97	75.362	ENSG00000132661	NXT1	99	75.362

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000101888	NXT2	99	81.739	ENSAPOG00000010308	nxt2	100	78.322	Acanthochromis_polyacanthus
ENSG00000101888	NXT2	100	88.889	ENSAMEG00000017999	NXT2	87	81.657	Ailuropoda_melanoleuca
ENSG00000101888	NXT2	99	80.000	ENSACIG00000015026	nxt2	100	76.923	Amphilophus_citrinellus
ENSG00000101888	NXT2	99	81.739	ENSAOCG00000007411	nxt2	100	78.322	Amphiprion_ocellaris
ENSG00000101888	NXT2	99	81.739	ENSAPEG00000010454	nxt2	100	78.322	Amphiprion_percula
ENSG00000101888	NXT2	99	81.739	ENSATEG00000020315	nxt2	100	78.322	Anabas_testudineus
ENSG00000101888	NXT2	99	79.577	ENSACAG00000012649	NXT2	99	79.021	Anolis_carolinensis
ENSG00000101888	NXT2	100	94.737	ENSANAG00000038165	NXT2	97	94.161	Aotus_nancymaae
ENSG00000101888	NXT2	99	79.130	ENSACLG00000025072	nxt2	100	76.923	Astatotilapia_calliptera
ENSG00000101888	NXT2	99	78.261	ENSAMXG00000031355	nxt2	100	75.524	Astyanax_mexicanus
ENSG00000101888	NXT2	99	91.150	ENSBTAG00000020739	NXT2	99	90.071	Bos_taurus
ENSG00000101888	NXT2	100	95.614	ENSCJAG00000007369	NXT2	100	83.838	Callithrix_jacchus
ENSG00000101888	NXT2	100	90.141	ENSCAFG00000028574	NXT2	100	78.894	Canis_familiaris
ENSG00000101888	NXT2	100	90.141	ENSCAFG00020005721	NXT2	100	90.141	Canis_lupus_dingo
ENSG00000101888	NXT2	99	90.265	ENSCHIG00000000279	NXT2	99	89.362	Capra_hircus
ENSG00000101888	NXT2	100	91.228	ENSTSYG00000001924	NXT2	100	90.845	Carlito_syrichta
ENSG00000101888	NXT2	100	85.965	ENSCPOG00000035559	-	100	85.965	Cavia_porcellus
ENSG00000101888	NXT2	100	97.368	ENSCCAG00000035523	NXT2	100	87.879	Cebus_capucinus
ENSG00000101888	NXT2	100	99.123	ENSCATG00000037402	NXT2	100	92.386	Cercocebus_atys
ENSG00000101888	NXT2	100	84.211	ENSCLAG00000001175	NXT2	100	68.528	Chinchilla_lanigera
ENSG00000101888	NXT2	100	98.246	ENSCSAG00000008842	NXT2	100	92.386	Chlorocebus_sabaeus
ENSG00000101888	NXT2	99	84.071	ENSCPBG00000000629	NXT2	100	82.979	Chrysemys_picta_bellii
ENSG00000101888	NXT2	100	98.246	ENSCANG00000041728	NXT2	100	89.848	Colobus_angolensis_palliatus
ENSG00000101888	NXT2	99	85.714	ENSCGRG00001021749	Nxt2	99	73.737	Cricetulus_griseus_chok1gshd
ENSG00000101888	NXT2	93	83.019	ENSCGRG00000001378	-	99	82.243	Cricetulus_griseus_crigri
ENSG00000101888	NXT2	99	78.261	ENSCSEG00000018710	nxt2	100	76.224	Cynoglossus_semilaevis
ENSG00000101888	NXT2	99	78.261	ENSCVAG00000021187	nxt2	100	76.224	Cyprinodon_variegatus
ENSG00000101888	NXT2	98	76.316	ENSDARG00000061527	nxt2	100	72.993	Danio_rerio
ENSG00000101888	NXT2	99	91.489	ENSDNOG00000039271	NXT2	99	91.489	Dasypus_novemcinctus
ENSG00000101888	NXT2	98	60.432	ENSDNOG00000043813	-	97	60.432	Dasypus_novemcinctus
ENSG00000101888	NXT2	100	81.739	ENSDORG00000010714	Nxt2	99	82.734	Dipodomys_ordii
ENSG00000101888	NXT2	100	80.702	ENSDORG00000013227	-	99	82.014	Dipodomys_ordii
ENSG00000101888	NXT2	98	81.250	ENSETEG00000008002	NXT2	100	69.192	Echinops_telfairi
ENSG00000101888	NXT2	100	92.254	ENSEASG00005019567	NXT2	100	92.254	Equus_asinus_asinus
ENSG00000101888	NXT2	100	92.982	ENSECAG00000015022	NXT2	100	80.303	Equus_caballus
ENSG00000101888	NXT2	100	85.088	ENSEEUG00000005675	-	99	85.926	Erinaceus_europaeus
ENSG00000101888	NXT2	95	90.741	ENSEEUG00000006109	-	99	66.463	Erinaceus_europaeus
ENSG00000101888	NXT2	99	76.522	ENSELUG00000005141	NXT2	100	72.727	Esox_lucius
ENSG00000101888	NXT2	100	90.351	ENSFCAG00000035855	NXT2	100	78.788	Felis_catus
ENSG00000101888	NXT2	99	86.525	ENSFALG00000000178	NXT2	100	86.525	Ficedula_albicollis
ENSG00000101888	NXT2	100	85.088	ENSFDAG00000011646	NXT2	100	73.232	Fukomys_damarensis
ENSG00000101888	NXT2	99	77.391	ENSFHEG00000001982	nxt2	100	74.825	Fundulus_heteroclitus
ENSG00000101888	NXT2	99	77.778	ENSGMOG00000003163	nxt2	100	76.552	Gadus_morhua
ENSG00000101888	NXT2	99	88.652	ENSGALG00000008092	NXT2	100	88.652	Gallus_gallus
ENSG00000101888	NXT2	99	78.261	ENSGAFG00000002714	nxt2	100	76.224	Gambusia_affinis
ENSG00000101888	NXT2	99	79.487	ENSGACG00000018508	nxt2	100	77.241	Gasterosteus_aculeatus
ENSG00000101888	NXT2	99	85.106	ENSGAGG00000017047	NXT2	100	85.106	Gopherus_agassizii
ENSG00000101888	NXT2	100	100.000	ENSGGOG00000013593	NXT2	100	98.477	Gorilla_gorilla
ENSG00000101888	NXT2	99	79.130	ENSHBUG00000002974	nxt2	100	76.923	Haplochromis_burtoni
ENSG00000101888	NXT2	100	86.842	ENSHGLG00000001921	NXT2	100	86.842	Heterocephalus_glaber_female
ENSG00000101888	NXT2	100	84.507	ENSHGLG00100002378	NXT2	100	84.507	Heterocephalus_glaber_male
ENSG00000101888	NXT2	99	79.130	ENSHCOG00000003893	nxt2	100	76.224	Hippocampus_comes
ENSG00000101888	NXT2	99	79.130	ENSIPUG00000000517	nxt2	100	76.224	Ictalurus_punctatus
ENSG00000101888	NXT2	100	92.105	ENSSTOG00000005243	NXT2	98	92.086	Ictidomys_tridecemlineatus
ENSG00000101888	NXT2	96	82.727	ENSJJAG00000000326	-	100	79.710	Jaculus_jaculus
ENSG00000101888	NXT2	99	72.566	ENSJJAG00000023288	-	97	73.913	Jaculus_jaculus
ENSG00000101888	NXT2	99	78.261	ENSKMAG00000016615	nxt2	100	76.224	Kryptolebias_marmoratus
ENSG00000101888	NXT2	99	80.000	ENSLBEG00000014298	nxt2	97	78.261	Labrus_bergylta
ENSG00000101888	NXT2	99	81.429	ENSLACG00000004286	NXT2	99	81.429	Latimeria_chalumnae
ENSG00000101888	NXT2	99	78.261	ENSLOCG00000014519	nxt2	100	76.923	Lepisosteus_oculatus
ENSG00000101888	NXT2	100	90.845	ENSLAFG00000007116	NXT2	100	85.542	Loxodonta_africana
ENSG00000101888	NXT2	100	98.246	ENSMFAG00000004105	NXT2	100	91.878	Macaca_fascicularis
ENSG00000101888	NXT2	100	98.246	ENSMMUG00000013204	NXT2	100	96.479	Macaca_mulatta
ENSG00000101888	NXT2	100	97.368	ENSMNEG00000010392	NXT2	100	97.368	Macaca_nemestrina
ENSG00000101888	NXT2	100	99.123	ENSMLEG00000041108	NXT2	100	92.386	Mandrillus_leucophaeus
ENSG00000101888	NXT2	99	81.739	ENSMAMG00000013603	nxt2	92	78.169	Mastacembelus_armatus
ENSG00000101888	NXT2	99	79.130	ENSMZEG00005007590	nxt2	100	76.923	Maylandia_zebra
ENSG00000101888	NXT2	98	88.489	ENSMGAG00000006597	NXT2	99	88.489	Meleagris_gallopavo
ENSG00000101888	NXT2	99	85.841	ENSMAUG00000000496	Nxt2	99	85.106	Mesocricetus_auratus
ENSG00000101888	NXT2	100	77.465	ENSMICG00000014848	-	91	77.465	Microcebus_murinus
ENSG00000101888	NXT2	100	92.254	ENSMICG00000014511	-	100	81.818	Microcebus_murinus
ENSG00000101888	NXT2	100	89.474	ENSMICG00000017900	-	97	90.511	Microcebus_murinus
ENSG00000101888	NXT2	99	81.416	ENSMOCG00000007176	Nxt2	99	81.159	Microtus_ochrogaster
ENSG00000101888	NXT2	99	71.552	ENSMMOG00000009472	nxt2	100	70.833	Mola_mola
ENSG00000101888	NXT2	99	82.301	ENSMODG00000021343	-	100	82.482	Monodelphis_domestica
ENSG00000101888	NXT2	99	77.876	ENSMODG00000011492	-	99	77.305	Monodelphis_domestica
ENSG00000101888	NXT2	99	81.739	ENSMALG00000006390	nxt2	100	78.322	Monopterus_albus
ENSG00000101888	NXT2	99	88.496	MGP_CAROLIEiJ_G0033463	Nxt2	99	88.496	Mus_caroli
ENSG00000101888	NXT2	99	88.496	ENSMUSG00000042271	Nxt2	99	88.496	Mus_musculus
ENSG00000101888	NXT2	99	87.943	MGP_PahariEiJ_G0032003	Nxt2	99	87.943	Mus_pahari
ENSG00000101888	NXT2	99	88.496	MGP_SPRETEiJ_G0034634	Nxt2	99	88.496	Mus_spretus
ENSG00000101888	NXT2	100	91.549	ENSMPUG00000003973	NXT2	100	81.000	Mustela_putorius_furo
ENSG00000101888	NXT2	100	89.474	ENSMLUG00000000631	NXT2	87	83.432	Myotis_lucifugus
ENSG00000101888	NXT2	99	86.525	ENSNGAG00000015935	Nxt2	99	86.525	Nannospalax_galili
ENSG00000101888	NXT2	99	80.000	ENSNBRG00000019401	nxt2	100	77.622	Neolamprologus_brichardi
ENSG00000101888	NXT2	100	98.592	ENSNLEG00000014331	NXT2	100	96.479	Nomascus_leucogenys
ENSG00000101888	NXT2	97	81.884	ENSMEUG00000001278	-	99	81.884	Notamacropus_eugenii
ENSG00000101888	NXT2	99	84.071	ENSMEUG00000000393	-	100	84.559	Notamacropus_eugenii
ENSG00000101888	NXT2	100	83.803	ENSODEG00000012049	NXT2	99	85.612	Octodon_degus
ENSG00000101888	NXT2	99	80.000	ENSONIG00000017566	nxt2	100	77.622	Oreochromis_niloticus
ENSG00000101888	NXT2	99	85.841	ENSOANG00000011441	NXT2	93	85.816	Ornithorhynchus_anatinus
ENSG00000101888	NXT2	99	92.199	ENSOCUG00000008261	NXT2	99	80.203	Oryctolagus_cuniculus
ENSG00000101888	NXT2	99	80.000	ENSORLG00000022600	nxt2	100	77.622	Oryzias_latipes
ENSG00000101888	NXT2	99	80.000	ENSORLG00020004703	nxt2	100	77.622	Oryzias_latipes_hni
ENSG00000101888	NXT2	99	80.000	ENSORLG00015008149	nxt2	100	77.622	Oryzias_latipes_hsok
ENSG00000101888	NXT2	98	80.702	ENSOMEG00000013420	nxt2	100	76.923	Oryzias_melastigma
ENSG00000101888	NXT2	100	92.254	ENSOGAG00000007890	-	100	80.100	Otolemur_garnettii
ENSG00000101888	NXT2	99	89.381	ENSOARG00000015625	-	98	82.390	Ovis_aries
ENSG00000101888	NXT2	99	89.381	ENSOARG00000018009	-	99	77.551	Ovis_aries
ENSG00000101888	NXT2	99	90.265	ENSOARG00000018574	-	98	83.019	Ovis_aries
ENSG00000101888	NXT2	100	100.000	ENSPPAG00000030159	NXT2	100	98.477	Pan_paniscus
ENSG00000101888	NXT2	100	90.351	ENSPPRG00000024610	NXT2	100	90.141	Panthera_pardus
ENSG00000101888	NXT2	100	80.328	ENSPTIG00000013174	NXT2	100	82.192	Panthera_tigris_altaica
ENSG00000101888	NXT2	100	100.000	ENSPTRG00000039310	NXT2	100	98.985	Pan_troglodytes
ENSG00000101888	NXT2	100	99.123	ENSPANG00000018449	NXT2	100	97.887	Papio_anubis
ENSG00000101888	NXT2	99	79.130	ENSPKIG00000022011	nxt2	100	76.224	Paramormyrops_kingsleyae
ENSG00000101888	NXT2	99	85.841	ENSPSIG00000006737	NXT2	78	80.000	Pelodiscus_sinensis
ENSG00000101888	NXT2	99	77.391	ENSPMGG00000000629	nxt2	100	74.825	Periophthalmus_magnuspinnatus
ENSG00000101888	NXT2	99	81.416	ENSPCIG00000008562	-	96	77.027	Phascolarctos_cinereus
ENSG00000101888	NXT2	99	79.130	ENSPFOG00000007462	nxt2	100	76.923	Poecilia_formosa
ENSG00000101888	NXT2	99	79.130	ENSPLAG00000002080	nxt2	100	76.923	Poecilia_latipinna
ENSG00000101888	NXT2	99	79.130	ENSPMEG00000008382	nxt2	100	76.923	Poecilia_mexicana
ENSG00000101888	NXT2	100	97.887	ENSPPYG00000020625	-	100	97.887	Pongo_abelii
ENSG00000101888	NXT2	100	83.099	ENSPCAG00000008006	NXT2	100	70.202	Procavia_capensis
ENSG00000101888	NXT2	100	90.845	ENSPCOG00000024004	NXT2	100	90.845	Propithecus_coquereli
ENSG00000101888	NXT2	100	92.105	ENSPVAG00000006149	NXT2	99	81.053	Pteropus_vampyrus
ENSG00000101888	NXT2	99	79.130	ENSPNYG00000024009	nxt2	100	76.923	Pundamilia_nyererei
ENSG00000101888	NXT2	98	78.947	ENSPNAG00000025785	nxt2	100	75.524	Pygocentrus_nattereri
ENSG00000101888	NXT2	99	88.496	ENSRNOG00000019168	Nxt2	93	81.875	Rattus_norvegicus
ENSG00000101888	NXT2	100	98.246	ENSRROG00000036216	NXT2	100	97.183	Rhinopithecus_roxellana
ENSG00000101888	NXT2	100	96.491	ENSSBOG00000029386	NXT2	97	97.080	Saimiri_boliviensis_boliviensis
ENSG00000101888	NXT2	59	72.619	ENSSHAG00000001265	-	93	72.619	Sarcophilus_harrisii
ENSG00000101888	NXT2	98	83.929	ENSSHAG00000002955	-	95	84.559	Sarcophilus_harrisii
ENSG00000101888	NXT2	98	83.453	ENSSHAG00000010539	-	98	83.453	Sarcophilus_harrisii
ENSG00000101888	NXT2	99	79.130	ENSSFOG00015009870	nxt2	100	76.224	Scleropages_formosus
ENSG00000101888	NXT2	99	80.000	ENSSMAG00000010366	nxt2	100	77.622	Scophthalmus_maximus
ENSG00000101888	NXT2	97	80.531	ENSSDUG00000011075	nxt2	69	77.305	Seriola_dumerili
ENSG00000101888	NXT2	99	79.130	ENSSLDG00000024416	nxt2	99	77.536	Seriola_lalandi_dorsalis
ENSG00000101888	NXT2	99	79.130	ENSSLDG00000002946	-	100	74.825	Seriola_lalandi_dorsalis
ENSG00000101888	NXT2	99	79.130	ENSSLDG00000001314	nxt2	99	77.536	Seriola_lalandi_dorsalis
ENSG00000101888	NXT2	98	84.892	ENSSARG00000009307	NXT2	94	72.043	Sorex_araneus
ENSG00000101888	NXT2	97	86.232	ENSSPUG00000000372	NXT2	98	86.232	Sphenodon_punctatus
ENSG00000101888	NXT2	99	80.000	ENSSPAG00000015263	nxt2	100	76.923	Stegastes_partitus
ENSG00000101888	NXT2	100	92.254	ENSSSCG00000012581	NXT2	100	92.254	Sus_scrofa
ENSG00000101888	NXT2	99	85.915	ENSTGUG00000004286	NXT2	100	85.915	Taeniopygia_guttata
ENSG00000101888	NXT2	99	79.130	ENSTRUG00000004111	nxt2	99	76.259	Takifugu_rubripes
ENSG00000101888	NXT2	99	76.522	ENSTNIG00000015787	nxt2	100	74.820	Tetraodon_nigroviridis
ENSG00000101888	NXT2	89	86.139	ENSTBEG00000003562	-	100	86.139	Tupaia_belangeri
ENSG00000101888	NXT2	89	85.149	ENSTBEG00000006311	-	100	85.149	Tupaia_belangeri
ENSG00000101888	NXT2	95	92.593	ENSTBEG00000007431	-	100	67.337	Tupaia_belangeri
ENSG00000101888	NXT2	100	85.965	ENSTTRG00000005115	NXT2	100	72.727	Tursiops_truncatus
ENSG00000101888	NXT2	100	91.228	ENSUAMG00000027383	NXT2	100	91.228	Ursus_americanus
ENSG00000101888	NXT2	100	91.228	ENSUMAG00000023095	NXT2	100	91.228	Ursus_maritimus
ENSG00000101888	NXT2	100	90.845	ENSVPAG00000007314	NXT2	100	76.263	Vicugna_pacos
ENSG00000101888	NXT2	100	90.141	ENSVVUG00000010575	NXT2	99	90.511	Vulpes_vulpes
ENSG00000101888	NXT2	98	71.942	ENSXETG00000008528	nxt2	99	71.942	Xenopus_tropicalis
ENSG00000101888	NXT2	99	79.130	ENSXCOG00000011172	nxt2	99	77.536	Xiphophorus_couchianus
ENSG00000101888	NXT2	99	79.130	ENSXMAG00000022277	nxt2	100	76.923	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0005515	protein binding	16189514.21516116.25416956.	IPI	Function
GO:0005654	nucleoplasm	-	IDA	Component
GO:0005829	cytosol	-	IDA	Component
GO:0006606	protein import into nucleus	21873635.	IBA	Process
GO:0006913	nucleocytoplasmic transport	21873635.	IBA	Process
GO:0008565	protein transporter activity	21873635.	IBA	Function
GO:0044613	nuclear pore central transport channel	21873635.	IBA	Component
GO:0048471	perinuclear region of cytoplasm	-	ISS	Component
GO:0051028	mRNA transport	-	IEA	Process