EuRBPDB

Description

RBPome

Literatures

Expression

Transcripts

Gene Model

Pathways

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000102119 (Gene tree)
Gene ID: 2010
Gene Symbol: EMD
Alias: STA|LEMD5
Full Name: emerin
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Plus strand
Length: 2,327 bases
Position: chrX:154,379,197-154,381,523
Accession: 3331
RBP type: non-canonical RBP
Summary: Emerin is a serine-rich nuclear membrane protein and a member of the nuclear lamina-associated protein family. It mediates membrane anchorage to the cytoskeleton. Dreifuss-Emery muscular dystrophy is an X-linked inherited degenerative myopathy resulting from mutation in the emerin gene. [provided by RefSeq, Jul 2008]

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
11352637	Induction of stearoyl CoA desaturase is associated with high-level induction of emerin RNA.	Biochem Biophys Res Commun	2001 Apr 13	Mziaut H	-

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000471965	EMD-205	800	-	-	- (aa)	-	-
ENST00000486738	EMD-207	1284	-	-	- (aa)	-	-
ENST00000492448	EMD-208	832	-	-	- (aa)	-	-
ENST00000494443	EMD-209	765	-	-	- (aa)	-	-
ENST00000485261	EMD-206	792	-	-	- (aa)	-	-
ENST00000428228	EMD-203	946	-	ENSP00000401081	21 (aa)	-	F8WEQ1
ENST00000369842	EMD-202	1379	-	ENSP00000358857	254 (aa)	-	P50402
ENST00000369835	EMD-201	966	XM_024452349	ENSP00000358850	219 (aa)	XP_024308117	Q5HY57
ENST00000468294	EMD-204	501	-	-	- (aa)	-	-

Gene Model

Click here to download ENSG00000102119's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa05410	Hypertrophic cardiomyopathy (HCM)	KEGG
hsa05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	KEGG
hsa05414	Dilated cardiomyopathy (DCM)	KEGG

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000102119's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs identified by RBPome

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000102119	EMD	100	74.545	ENSMUSG00000001964	Emd	98	75.000	Mus_musculus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0003779	actin binding	21873635.	IBA	Function
GO:0003779	actin binding	15328537.	IDA	Function
GO:0005515	protein binding	12163176.15009215.15328537.15671068.16169070.16189514.16858403.17462627.19323649.19933576.21610090.22399800.25416956.25910212.27107012.	IPI	Function
GO:0005635	nuclear envelope	21873635.	IBA	Component
GO:0005635	nuclear envelope	16858403.27534416.	IDA	Component
GO:0005635	nuclear envelope	21610090.	IMP	Component
GO:0005635	nuclear envelope	-	TAS	Component
GO:0005637	nuclear inner membrane	21873635.	IBA	Component
GO:0005637	nuclear inner membrane	19167377.	IDA	Component
GO:0005637	nuclear inner membrane	16858403.	NAS	Component
GO:0005640	nuclear outer membrane	17785515.	IDA	Component
GO:0005654	nucleoplasm	27534416.	IDA	Component
GO:0005737	cytoplasm	27534416.	IDA	Component
GO:0005783	endoplasmic reticulum	-	IDA	Component
GO:0005819	spindle	21873635.	IBA	Component
GO:0005874	microtubule	-	IEA	Component
GO:0006936	muscle contraction	7894480.	TAS	Process
GO:0007084	mitotic nuclear envelope reassembly	-	TAS	Process
GO:0007517	muscle organ development	7894480.8589715.	TAS	Process
GO:0016020	membrane	19946888.	HDA	Component
GO:0016021	integral component of membrane	-	IEA	Component
GO:0031616	spindle pole centrosome	19494128.	IDA	Component
GO:0031965	nuclear membrane	21873635.	IBA	Component
GO:0031965	nuclear membrane	-	IDA	Component
GO:0032541	cortical endoplasmic reticulum	19494128.	IDA	Component
GO:0035914	skeletal muscle cell differentiation	-	IEA	Process
GO:0045296	cadherin binding	25468996.	HDA	Function
GO:0046827	positive regulation of protein export from nucleus	16858403.	IMP	Process
GO:0048147	negative regulation of fibroblast proliferation	16858403.	IMP	Process
GO:0048487	beta-tubulin binding	21873635.	IBA	Function
GO:0048487	beta-tubulin binding	17785515.	IDA	Function
GO:0060828	regulation of canonical Wnt signaling pathway	16858403.	IMP	Process
GO:0071363	cellular response to growth factor stimulus	16858403.	IMP	Process
GO:0090090	negative regulation of canonical Wnt signaling pathway	21873635.	IBA	Process
GO:0090090	negative regulation of canonical Wnt signaling pathway	16858403.	IMP	Process