EuRBPDB

Description

Ensembl ID: ENSG00000102316 (Gene tree)
Gene ID: 10916
Gene Symbol: MAGED2
Alias: JCL-1|BCG1|11B6|MAGE-D2|HCA10|MAGED|MGC8386
Full Name: MAGE family member D2
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Plus strand
Length: 8,417 bases
Position: chrX:54,807,599-54,816,015
Accession: 16353
RBP type: non-canonical RBP
Summary: This gene is a member of the MAGED gene family. The MAGED genes are clustered on chromosome Xp11. This gene is located in Xp11.2, a hot spot for X-linked intellectual disability (XLID). Mutations in this gene cause a form of transient antenatal Bartter's syndrome. This gene may also be involved in several types of cancer, including breast cancer and melanoma. The protein encoded by this gene is progressively recruited from the cytoplasm to the nucleoplasm during the interphase and after nucleolar stress and is thus thought to play a role in cell cycle regulation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2017]

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
29431736	Capturing the interactome of newly transcribed RNA	PolyT-RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000396224	MAGED2-207	2026	-	ENSP00000379526	606 (aa)	-	Q9UNF1
ENST00000218439	MAGED2-201	1958	-	ENSP00000218439	606 (aa)	-	Q9UNF1
ENST00000485483	MAGED2-209	691	-	-	- (aa)	-	-
ENST00000375068	MAGED2-206	2189	-	ENSP00000364209	606 (aa)	-	Q9UNF1
ENST00000375060	MAGED2-205	1798	-	ENSP00000364200	521 (aa)	-	Q5H907
ENST00000497484	MAGED2-212	990	-	-	- (aa)	-	-
ENST00000347546	MAGED2-202	2177	-	ENSP00000336962	588 (aa)	-	Q5H909
ENST00000375053	MAGED2-203	2066	-	ENSP00000364193	606 (aa)	-	Q9UNF1
ENST00000627068	MAGED2-213	1811	-	ENSP00000486563	521 (aa)	-	Q5H907
ENST00000463787	MAGED2-208	662	-	-	- (aa)	-	-
ENST00000487463	MAGED2-210	376	-	-	- (aa)	-	-
ENST00000375058	MAGED2-204	2048	-	ENSP00000364198	606 (aa)	-	Q9UNF1
ENST00000487482	MAGED2-211	341	-	-	- (aa)	-	-

Gene Model

Protein-Protein Interaction (PPI)

* RBP PPI network refers to all genes directly bind to RBP

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0002576	platelet degranulation	-	TAS	Process
GO:0005515	protein binding	25852190.27120771.	IPI	Function
GO:0005576	extracellular region	-	TAS	Component
GO:0005634	nucleus	-	IDA	Component
GO:0005730	nucleolus	-	IDA	Component
GO:0005829	cytosol	-	IDA	Component
GO:0007565	female pregnancy	27120771.	IMP	Process
GO:0016020	membrane	19946888.	HDA	Component
GO:0031093	platelet alpha granule lumen	-	TAS	Component
GO:0070294	renal sodium ion absorption	27120771.	IMP	Process