EuRBPDB

Basic Information
Cancer Related Information

Description

RBDs

Literatures

Expression

Transcripts

Gene Model

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000102898 (Gene tree)
Gene ID: 10204
Gene Symbol: NUTF2
Alias: NTF2|PP15
Full Name: nuclear transport factor 2
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Plus strand
Length: 25,836 bases
Position: chr16:67,846,732-67,872,567
Accession: 13722
RBP type: canonical RBP
Summary: This gene encodes a cytosolic factor that facilitates protein transport into the nucleus. The encoded protein is required for nuclear import of the small Ras-like GTPase, Ran which is involved in numerous cellular processes. This protein also interacts with the nuclear pore complex glycoprotein p62. [provided by RefSeq, Apr 2016]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000219169	NTF2	PF02136.20	3e-32	1	1
ENSP00000457022	NTF2	PF02136.20	3e-32	1	1
ENSP00000457989	NTF2	PF02136.20	3e-32	1	1
ENSP00000456428	NTF2	PF02136.20	7.7e-27	1	1

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
29473141	The Trypanosoma cruzi RNA-binding protein RBP42 is expressed in the cytoplasm throughout the life cycle of the parasite.	Parasitol Res	2018 Apr	Tyler Weisbarth R	doi: 10.1007/s00436-018-5787-9
8804825	Structural classification of proteins: new superfamilies.	Curr Opin Struct Biol	1996 Jun	Murzin AG	-
10969074	IkappaBalpha and IkappaBalpha /NF-kappa B complexes are retained in the cytoplasm through interaction with a novel partner, RasGAP SH3-binding protein 2.	J Biol Chem	2000 Nov 17	Prigent M	-
25618852	Domain organization within the nuclear export factor Mex67:Mtr2 generates an extended mRNA binding surface.	Nucleic Acids Res	2015 Feb 18	Aibara S	doi: 10.1093/nar/gkv030
25628361	The principal mRNA nuclear export factor NXF1:NXT1 forms a symmetric binding platform that facilitates export of retroviral CTE-RNA.	Nucleic Acids Res	2015 Feb 18	Aibara S	doi: 10.1093/nar/gkv032
17623797	Histone deacetylase 1 gene expression and sensitization of multidrug-resistant neuroblastoma cell lines to cytotoxic agents by depsipeptide.	J Natl Cancer Inst	2007 Jul 18	Keshelava N	-

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000587481	NUTF2-208	2608	-	-	- (aa)	-	-
ENST00000219169	NUTF2-201	2321	-	ENSP00000219169	127 (aa)	-	P61970
ENST00000568233	NUTF2-203	589	-	-	- (aa)	-	-
ENST00000570026	NUTF2-207	400	-	-	- (aa)	-	-
ENST00000568396	NUTF2-205	1179	-	ENSP00000457022	127 (aa)	-	P61970
ENST00000569436	NUTF2-206	1119	-	ENSP00000457989	127 (aa)	-	P61970
ENST00000567105	NUTF2-202	582	-	ENSP00000456428	107 (aa)	-	H3BRV9
ENST00000568390	NUTF2-204	593	-	-	- (aa)	-	-

Gene Model

Click here to download ENSG00000102898's gene model file

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000102898	Cholesterol, HDL	4.657e-008	19060910
ENSG00000102898	Cholesterol, HDL	8E-16	19060911
ENSG00000102898	Cholesterol, HDL	9E-13	19060906

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000102898	rs2271293	16	67868167	A	HDL cholesterol	19060906	[0.01-0.13] s.d. increase	0.07	EFO_0004612
ENSG00000102898	rs2271293	16	67868167	G	HDL cholesterol	19060911	[NR] s.d. decrease	0.13	EFO_0004612
ENSG00000102898	rs1124324	16	67863584	C	High density lipoprotein cholesterol levels	29507422	unit decrease	0.076	EFO_0004612
ENSG00000102898	rs1124324	16	67863584	C	High density lipoprotein cholesterol levels	29507422	unit decrease	0.086	EFO_0004612
ENSG00000102898	rs1124324	16	67863584	C	High density lipoprotein cholesterol levels	29507422	unit decrease	0.077	EFO_0004612

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000102898's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000102898	NUTF2	97	58.065	ENSAPOG00000018369	-	95	58.065	Acanthochromis_polyacanthus
ENSG00000102898	NUTF2	100	87.402	ENSAPOG00000002504	nutf2	100	87.402	Acanthochromis_polyacanthus
ENSG00000102898	NUTF2	100	100.000	ENSAMEG00000017548	-	100	100.000	Ailuropoda_melanoleuca
ENSG00000102898	NUTF2	100	79.528	ENSAMEG00000018926	-	100	79.528	Ailuropoda_melanoleuca
ENSG00000102898	NUTF2	100	70.079	ENSACIG00000011973	nutf2	100	70.079	Amphilophus_citrinellus
ENSG00000102898	NUTF2	97	58.065	ENSACIG00000016248	-	96	58.537	Amphilophus_citrinellus
ENSG00000102898	NUTF2	97	58.065	ENSAOCG00000002011	-	95	58.065	Amphiprion_ocellaris
ENSG00000102898	NUTF2	100	87.402	ENSAOCG00000002672	nutf2	100	87.402	Amphiprion_ocellaris
ENSG00000102898	NUTF2	97	58.065	ENSAPEG00000011058	-	95	58.065	Amphiprion_percula
ENSG00000102898	NUTF2	100	87.402	ENSAPEG00000023864	nutf2	100	87.402	Amphiprion_percula
ENSG00000102898	NUTF2	97	58.065	ENSATEG00000013439	-	95	58.065	Anabas_testudineus
ENSG00000102898	NUTF2	100	85.827	ENSATEG00000009785	nutf2	100	85.827	Anabas_testudineus
ENSG00000102898	NUTF2	100	86.614	ENSAPLG00000009210	NUTF2	100	86.614	Anas_platyrhynchos
ENSG00000102898	NUTF2	100	95.327	ENSACAG00000028758	NUTF2	91	87.200	Anolis_carolinensis
ENSG00000102898	NUTF2	100	95.327	ENSANAG00000007268	-	100	94.488	Aotus_nancymaae
ENSG00000102898	NUTF2	100	100.000	ENSANAG00000024931	NUTF2	100	100.000	Aotus_nancymaae
ENSG00000102898	NUTF2	100	94.488	ENSANAG00000010232	-	100	94.488	Aotus_nancymaae
ENSG00000102898	NUTF2	100	87.850	ENSANAG00000015816	-	100	87.402	Aotus_nancymaae
ENSG00000102898	NUTF2	100	78.906	ENSANAG00000032973	-	100	78.906	Aotus_nancymaae
ENSG00000102898	NUTF2	97	58.065	ENSACLG00000015089	-	95	58.065	Astatotilapia_calliptera
ENSG00000102898	NUTF2	100	87.402	ENSACLG00000021149	nutf2	100	87.402	Astatotilapia_calliptera
ENSG00000102898	NUTF2	100	59.843	ENSAMXG00000034988	nutf2l	99	59.843	Astyanax_mexicanus
ENSG00000102898	NUTF2	100	91.589	ENSAMXG00000039269	nutf2	94	91.339	Astyanax_mexicanus
ENSG00000102898	NUTF2	100	100.000	ENSBTAG00000006414	NUTF2	100	100.000	Bos_taurus
ENSG00000102898	NUTF2	99	45.536	WBGene00004305	ran-4	99	44.697	Caenorhabditis_elegans
ENSG00000102898	NUTF2	100	100.000	ENSCJAG00000043529	-	100	100.000	Callithrix_jacchus
ENSG00000102898	NUTF2	100	100.000	ENSCJAG00000041369	-	100	100.000	Callithrix_jacchus
ENSG00000102898	NUTF2	100	72.414	ENSCAFG00000007926	-	99	67.647	Canis_familiaris
ENSG00000102898	NUTF2	100	85.981	ENSCAFG00000016393	-	100	85.039	Canis_familiaris
ENSG00000102898	NUTF2	100	99.065	ENSCAFG00000012004	-	100	98.425	Canis_familiaris
ENSG00000102898	NUTF2	100	92.913	ENSCAFG00020000736	-	100	92.913	Canis_lupus_dingo
ENSG00000102898	NUTF2	100	99.213	ENSCAFG00020013259	-	100	99.213	Canis_lupus_dingo
ENSG00000102898	NUTF2	100	100.000	ENSCAFG00020018500	-	100	100.000	Canis_lupus_dingo
ENSG00000102898	NUTF2	100	100.000	ENSCHIG00000024970	-	100	100.000	Capra_hircus
ENSG00000102898	NUTF2	94	63.866	ENSCHIG00000026347	-	93	63.866	Capra_hircus
ENSG00000102898	NUTF2	100	100.000	ENSTSYG00000027970	NUTF2	100	100.000	Carlito_syrichta
ENSG00000102898	NUTF2	100	100.000	ENSCPOG00000037906	-	100	100.000	Cavia_porcellus
ENSG00000102898	NUTF2	100	70.079	ENSCCAG00000025186	-	100	70.079	Cebus_capucinus
ENSG00000102898	NUTF2	100	100.000	ENSCCAG00000027242	-	100	100.000	Cebus_capucinus
ENSG00000102898	NUTF2	98	77.419	ENSCCAG00000002965	-	87	77.419	Cebus_capucinus
ENSG00000102898	NUTF2	100	100.000	ENSCATG00000027997	-	100	100.000	Cercocebus_atys
ENSG00000102898	NUTF2	95	71.429	ENSCATG00000037870	-	98	71.429	Cercocebus_atys
ENSG00000102898	NUTF2	100	82.677	ENSCATG00000002586	-	100	82.677	Cercocebus_atys
ENSG00000102898	NUTF2	100	75.385	ENSCATG00000043408	-	100	75.385	Cercocebus_atys
ENSG00000102898	NUTF2	100	97.638	ENSCLAG00000005377	NUTF2	100	97.638	Chinchilla_lanigera
ENSG00000102898	NUTF2	100	100.000	ENSCSAG00000003952	-	100	100.000	Chlorocebus_sabaeus
ENSG00000102898	NUTF2	100	89.764	ENSCHOG00000003059	NUTF2	100	89.764	Choloepus_hoffmanni
ENSG00000102898	NUTF2	100	88.976	ENSCPBG00000015840	NUTF2	99	83.200	Chrysemys_picta_bellii
ENSG00000102898	NUTF2	100	72.441	ENSCPBG00000006442	-	100	72.441	Chrysemys_picta_bellii
ENSG00000102898	NUTF2	92	42.000	ENSCING00000023354	-	86	41.176	Ciona_intestinalis
ENSG00000102898	NUTF2	100	77.099	ENSCANG00000036858	-	79	77.099	Colobus_angolensis_palliatus
ENSG00000102898	NUTF2	100	83.465	ENSCANG00000036557	-	100	83.465	Colobus_angolensis_palliatus
ENSG00000102898	NUTF2	100	79.528	ENSCANG00000001430	-	100	79.528	Colobus_angolensis_palliatus
ENSG00000102898	NUTF2	100	100.000	ENSCANG00000009746	-	100	100.000	Colobus_angolensis_palliatus
ENSG00000102898	NUTF2	100	98.131	ENSCANG00000016587	-	100	96.850	Colobus_angolensis_palliatus
ENSG00000102898	NUTF2	100	91.339	ENSCANG00000012248	-	100	91.339	Colobus_angolensis_palliatus
ENSG00000102898	NUTF2	100	90.551	ENSCGRG00001000908	-	100	90.551	Cricetulus_griseus_chok1gshd
ENSG00000102898	NUTF2	100	100.000	ENSCGRG00001015597	-	100	100.000	Cricetulus_griseus_chok1gshd
ENSG00000102898	NUTF2	100	85.039	ENSCGRG00001024026	-	100	85.039	Cricetulus_griseus_chok1gshd
ENSG00000102898	NUTF2	100	100.000	ENSCGRG00000016446	Nutf2	100	100.000	Cricetulus_griseus_crigri
ENSG00000102898	NUTF2	100	85.039	ENSCGRG00000002795	-	100	85.039	Cricetulus_griseus_crigri
ENSG00000102898	NUTF2	100	78.740	ENSCSEG00000014025	nutf2	100	78.740	Cynoglossus_semilaevis
ENSG00000102898	NUTF2	95	59.223	ENSCVAG00000023116	-	95	59.504	Cyprinodon_variegatus
ENSG00000102898	NUTF2	100	82.677	ENSCVAG00000006091	nutf2	100	82.677	Cyprinodon_variegatus
ENSG00000102898	NUTF2	100	92.126	ENSDARG00000056531	nutf2	100	92.126	Danio_rerio
ENSG00000102898	NUTF2	100	73.228	ENSDARG00000014499	nutf2l	99	73.228	Danio_rerio
ENSG00000102898	NUTF2	100	100.000	ENSDORG00000027828	-	100	100.000	Dipodomys_ordii
ENSG00000102898	NUTF2	93	45.631	FBgn0032680	Ntf-2r	94	43.443	Drosophila_melanogaster
ENSG00000102898	NUTF2	99	43.119	FBgn0031145	Ntf-2	98	44.828	Drosophila_melanogaster
ENSG00000102898	NUTF2	74	97.872	ENSETEG00000016354	NUTF2	100	97.872	Echinops_telfairi
ENSG00000102898	NUTF2	97	73.171	ENSEBUG00000004510	nutf2l	74	73.171	Eptatretus_burgeri
ENSG00000102898	NUTF2	100	100.000	ENSEASG00005012928	-	100	100.000	Equus_asinus_asinus
ENSG00000102898	NUTF2	100	100.000	ENSECAG00000021530	NUTF2	100	100.000	Equus_caballus
ENSG00000102898	NUTF2	100	100.000	ENSEEUG00000003470	NUTF2	100	100.000	Erinaceus_europaeus
ENSG00000102898	NUTF2	100	92.913	ENSELUG00000016781	nutf2	100	92.913	Esox_lucius
ENSG00000102898	NUTF2	100	73.228	ENSELUG00000012588	NTF2	99	73.228	Esox_lucius
ENSG00000102898	NUTF2	100	100.000	ENSFCAG00000008167	-	100	100.000	Felis_catus
ENSG00000102898	NUTF2	100	91.589	ENSFALG00000007057	NUTF2	99	88.800	Ficedula_albicollis
ENSG00000102898	NUTF2	100	98.425	ENSFDAG00000008588	NUTF2	100	98.425	Fukomys_damarensis
ENSG00000102898	NUTF2	99	57.944	ENSFHEG00000019605	-	96	58.400	Fundulus_heteroclitus
ENSG00000102898	NUTF2	100	83.465	ENSFHEG00000000689	nutf2	100	83.465	Fundulus_heteroclitus
ENSG00000102898	NUTF2	98	57.143	ENSGMOG00000002076	-	97	57.143	Gadus_morhua
ENSG00000102898	NUTF2	100	96.850	ENSGALG00000001602	NUTF2	100	96.850	Gallus_gallus
ENSG00000102898	NUTF2	98	58.400	ENSGAFG00000010423	-	96	58.400	Gambusia_affinis
ENSG00000102898	NUTF2	100	66.142	ENSGAFG00000014760	nutf2	100	66.142	Gambusia_affinis
ENSG00000102898	NUTF2	100	72.441	ENSGAGG00000020494	-	100	72.441	Gopherus_agassizii
ENSG00000102898	NUTF2	100	88.189	ENSGAGG00000025661	NUTF2	100	88.189	Gopherus_agassizii
ENSG00000102898	NUTF2	100	79.528	ENSGGOG00000042658	-	100	79.528	Gorilla_gorilla
ENSG00000102898	NUTF2	100	100.000	ENSGGOG00000023925	NUTF2	100	100.000	Gorilla_gorilla
ENSG00000102898	NUTF2	100	80.315	ENSGGOG00000037483	-	100	80.315	Gorilla_gorilla
ENSG00000102898	NUTF2	100	87.402	ENSHBUG00000010303	nutf2	100	87.402	Haplochromis_burtoni
ENSG00000102898	NUTF2	97	58.065	ENSHBUG00000002401	-	95	58.065	Haplochromis_burtoni
ENSG00000102898	NUTF2	100	98.425	ENSHGLG00000011174	NUTF2	100	98.425	Heterocephalus_glaber_female
ENSG00000102898	NUTF2	100	98.425	ENSHGLG00100013090	NUTF2	100	98.425	Heterocephalus_glaber_male
ENSG00000102898	NUTF2	93	51.261	ENSHCOG00000019195	-	89	51.261	Hippocampus_comes
ENSG00000102898	NUTF2	100	68.504	ENSHCOG00000012264	nutf2l	100	68.504	Hippocampus_comes
ENSG00000102898	NUTF2	100	92.126	ENSIPUG00000003516	nutf2	100	92.126	Ictalurus_punctatus
ENSG00000102898	NUTF2	100	99.213	ENSSTOG00000002878	-	100	99.213	Ictidomys_tridecemlineatus
ENSG00000102898	NUTF2	100	99.065	ENSJJAG00000021665	-	100	98.425	Jaculus_jaculus
ENSG00000102898	NUTF2	97	58.065	ENSKMAG00000007483	-	95	58.065	Kryptolebias_marmoratus
ENSG00000102898	NUTF2	100	84.252	ENSKMAG00000020975	nutf2	100	84.252	Kryptolebias_marmoratus
ENSG00000102898	NUTF2	100	85.039	ENSLBEG00000009175	nutf2	100	85.039	Labrus_bergylta
ENSG00000102898	NUTF2	98	58.400	ENSLBEG00000027185	-	96	58.400	Labrus_bergylta
ENSG00000102898	NUTF2	100	89.764	ENSLACG00000016446	NUTF2	100	89.764	Latimeria_chalumnae
ENSG00000102898	NUTF2	100	87.037	ENSLOCG00000006733	nutf2	98	82.031	Lepisosteus_oculatus
ENSG00000102898	NUTF2	100	76.636	ENSLOCG00000008390	nutf2l	98	76.378	Lepisosteus_oculatus
ENSG00000102898	NUTF2	100	100.000	ENSLAFG00000031037	-	100	100.000	Loxodonta_africana
ENSG00000102898	NUTF2	100	100.000	ENSMFAG00000039088	NUTF2	100	100.000	Macaca_fascicularis
ENSG00000102898	NUTF2	100	90.654	ENSMFAG00000027212	-	100	89.764	Macaca_fascicularis
ENSG00000102898	NUTF2	100	77.099	ENSMFAG00000036777	-	100	77.099	Macaca_fascicularis
ENSG00000102898	NUTF2	100	76.154	ENSMFAG00000039880	-	100	76.154	Macaca_fascicularis
ENSG00000102898	NUTF2	100	75.385	ENSMMUG00000047359	-	100	75.385	Macaca_mulatta
ENSG00000102898	NUTF2	100	100.000	ENSMMUG00000012038	-	100	100.000	Macaca_mulatta
ENSG00000102898	NUTF2	100	74.046	ENSMMUG00000049043	-	100	74.046	Macaca_mulatta
ENSG00000102898	NUTF2	100	81.102	ENSMMUG00000038467	-	100	81.102	Macaca_mulatta
ENSG00000102898	NUTF2	100	100.000	ENSMNEG00000036679	-	100	100.000	Macaca_nemestrina
ENSG00000102898	NUTF2	100	78.740	ENSMNEG00000044873	-	100	78.740	Macaca_nemestrina
ENSG00000102898	NUTF2	100	88.785	ENSMNEG00000037578	-	100	88.189	Macaca_nemestrina
ENSG00000102898	NUTF2	100	76.154	ENSMNEG00000014845	-	100	76.154	Macaca_nemestrina
ENSG00000102898	NUTF2	100	77.099	ENSMNEG00000044293	-	100	77.099	Macaca_nemestrina
ENSG00000102898	NUTF2	100	100.000	ENSMLEG00000038462	NUTF2	100	100.000	Mandrillus_leucophaeus
ENSG00000102898	NUTF2	100	76.336	ENSMLEG00000038687	-	100	76.336	Mandrillus_leucophaeus
ENSG00000102898	NUTF2	100	80.315	ENSMLEG00000027496	-	100	80.315	Mandrillus_leucophaeus
ENSG00000102898	NUTF2	100	66.154	ENSMLEG00000043370	-	100	66.154	Mandrillus_leucophaeus
ENSG00000102898	NUTF2	100	85.827	ENSMAMG00000015483	nutf2	100	85.827	Mastacembelus_armatus
ENSG00000102898	NUTF2	97	58.065	ENSMAMG00000014124	-	95	58.065	Mastacembelus_armatus
ENSG00000102898	NUTF2	97	58.065	ENSMZEG00005003467	-	95	58.065	Maylandia_zebra
ENSG00000102898	NUTF2	100	87.402	ENSMZEG00005010269	nutf2	100	87.402	Maylandia_zebra
ENSG00000102898	NUTF2	100	96.850	ENSMGAG00000002707	NUTF2	100	96.850	Meleagris_gallopavo
ENSG00000102898	NUTF2	98	80.952	ENSMAUG00000001506	-	93	78.400	Mesocricetus_auratus
ENSG00000102898	NUTF2	100	100.000	ENSMAUG00000003769	Nutf2	100	100.000	Mesocricetus_auratus
ENSG00000102898	NUTF2	100	100.000	ENSMICG00000028936	NUTF2	100	100.000	Microcebus_murinus
ENSG00000102898	NUTF2	100	100.000	ENSMOCG00000019909	-	100	100.000	Microtus_ochrogaster
ENSG00000102898	NUTF2	98	76.613	ENSMMOG00000019729	nutf2	95	76.613	Mola_mola
ENSG00000102898	NUTF2	100	69.291	ENSMODG00000024672	-	100	69.291	Monodelphis_domestica
ENSG00000102898	NUTF2	100	71.028	ENSMODG00000020270	-	99	71.429	Monodelphis_domestica
ENSG00000102898	NUTF2	100	96.063	ENSMODG00000005517	-	100	96.063	Monodelphis_domestica
ENSG00000102898	NUTF2	100	84.252	ENSMALG00000006554	nutf2	100	84.252	Monopterus_albus
ENSG00000102898	NUTF2	97	57.258	ENSMALG00000005443	-	95	57.258	Monopterus_albus
ENSG00000102898	NUTF2	100	49.606	MGP_CAROLIEiJ_G0021747	-	56	97.297	Mus_caroli
ENSG00000102898	NUTF2	100	100.000	MGP_CAROLIEiJ_G0031499	-	100	100.000	Mus_caroli
ENSG00000102898	NUTF2	100	100.000	ENSMUSG00000008450	Nutf2	100	100.000	Mus_musculus
ENSG00000102898	NUTF2	100	100.000	ENSMUSG00000071497	Nutf2-ps1	100	100.000	Mus_musculus
ENSG00000102898	NUTF2	100	100.000	MGP_PahariEiJ_G0023099	Nutf2	100	100.000	Mus_pahari
ENSG00000102898	NUTF2	100	68.504	MGP_SPRETEiJ_G0022658	-	100	68.504	Mus_spretus
ENSG00000102898	NUTF2	100	100.000	MGP_SPRETEiJ_G0032617	-	100	100.000	Mus_spretus
ENSG00000102898	NUTF2	100	100.000	ENSMPUG00000006737	NUTF2	100	100.000	Mustela_putorius_furo
ENSG00000102898	NUTF2	99	84.127	ENSMLUG00000005846	-	99	84.127	Myotis_lucifugus
ENSG00000102898	NUTF2	100	99.213	ENSMLUG00000025175	-	100	99.213	Myotis_lucifugus
ENSG00000102898	NUTF2	100	100.000	ENSNGAG00000014712	Nutf2-ps1	100	100.000	Nannospalax_galili
ENSG00000102898	NUTF2	100	87.402	ENSNBRG00000008325	nutf2	100	87.402	Neolamprologus_brichardi
ENSG00000102898	NUTF2	97	58.065	ENSNBRG00000013403	-	95	58.065	Neolamprologus_brichardi
ENSG00000102898	NUTF2	100	82.677	ENSNLEG00000034779	-	100	82.677	Nomascus_leucogenys
ENSG00000102898	NUTF2	100	77.953	ENSNLEG00000033637	-	100	77.953	Nomascus_leucogenys
ENSG00000102898	NUTF2	100	100.000	ENSNLEG00000004889	-	100	100.000	Nomascus_leucogenys
ENSG00000102898	NUTF2	100	97.638	ENSMEUG00000009874	NUTF2	100	97.638	Notamacropus_eugenii
ENSG00000102898	NUTF2	84	100.000	ENSOPRG00000013727	-	100	100.000	Ochotona_princeps
ENSG00000102898	NUTF2	100	99.213	ENSODEG00000015563	-	100	99.213	Octodon_degus
ENSG00000102898	NUTF2	100	86.916	ENSODEG00000001597	-	98	86.916	Octodon_degus
ENSG00000102898	NUTF2	100	77.570	ENSODEG00000011785	-	100	77.165	Octodon_degus
ENSG00000102898	NUTF2	100	87.402	ENSONIG00000011111	nutf2	100	87.402	Oreochromis_niloticus
ENSG00000102898	NUTF2	93	88.889	ENSOANG00000010392	NUTF2	99	88.889	Ornithorhynchus_anatinus
ENSG00000102898	NUTF2	100	100.000	ENSOCUG00000025641	-	100	100.000	Oryctolagus_cuniculus
ENSG00000102898	NUTF2	100	70.866	ENSOCUG00000027660	-	100	70.866	Oryctolagus_cuniculus
ENSG00000102898	NUTF2	100	100.000	ENSOCUG00000006322	-	100	100.000	Oryctolagus_cuniculus
ENSG00000102898	NUTF2	98	56.349	ENSORLG00000022366	-	76	56.349	Oryzias_latipes
ENSG00000102898	NUTF2	100	81.102	ENSORLG00000023543	nutf2	100	81.102	Oryzias_latipes
ENSG00000102898	NUTF2	98	56.349	ENSORLG00020007034	-	98	56.349	Oryzias_latipes_hni
ENSG00000102898	NUTF2	100	81.102	ENSORLG00020018209	nutf2	100	81.102	Oryzias_latipes_hni
ENSG00000102898	NUTF2	100	81.102	ENSORLG00015009261	nutf2	100	81.102	Oryzias_latipes_hsok
ENSG00000102898	NUTF2	98	56.349	ENSORLG00015015025	-	98	56.349	Oryzias_latipes_hsok
ENSG00000102898	NUTF2	100	81.890	ENSOMEG00000013345	nutf2	100	81.890	Oryzias_melastigma
ENSG00000102898	NUTF2	99	55.140	ENSOMEG00000013092	-	98	55.556	Oryzias_melastigma
ENSG00000102898	NUTF2	100	100.000	ENSOGAG00000015568	NUTF2	100	100.000	Otolemur_garnettii
ENSG00000102898	NUTF2	100	100.000	ENSOARG00000003200	NUTF2	100	100.000	Ovis_aries
ENSG00000102898	NUTF2	100	79.528	ENSPPAG00000042939	-	100	79.528	Pan_paniscus
ENSG00000102898	NUTF2	100	85.039	ENSPPAG00000027690	-	100	85.039	Pan_paniscus
ENSG00000102898	NUTF2	100	78.740	ENSPPAG00000030537	-	100	78.740	Pan_paniscus
ENSG00000102898	NUTF2	100	100.000	ENSPPAG00000044012	-	100	100.000	Pan_paniscus
ENSG00000102898	NUTF2	100	100.000	ENSPPRG00000013687	-	100	100.000	Panthera_pardus
ENSG00000102898	NUTF2	100	100.000	ENSPTIG00000019759	NUTF2	100	100.000	Panthera_tigris_altaica
ENSG00000102898	NUTF2	100	78.740	ENSPTRG00000050740	-	100	78.740	Pan_troglodytes
ENSG00000102898	NUTF2	100	100.000	ENSPTRG00000008248	NUTF2	100	100.000	Pan_troglodytes
ENSG00000102898	NUTF2	100	79.528	ENSPTRG00000043495	-	100	79.528	Pan_troglodytes
ENSG00000102898	NUTF2	100	73.077	ENSPANG00000035493	-	100	73.077	Papio_anubis
ENSG00000102898	NUTF2	100	100.000	ENSPANG00000031155	-	100	100.000	Papio_anubis
ENSG00000102898	NUTF2	100	75.573	ENSPANG00000033582	-	100	75.573	Papio_anubis
ENSG00000102898	NUTF2	100	91.589	ENSPANG00000014057	-	100	91.339	Papio_anubis
ENSG00000102898	NUTF2	100	95.276	ENSPKIG00000002135	-	100	95.276	Paramormyrops_kingsleyae
ENSG00000102898	NUTF2	100	93.701	ENSPKIG00000001172	nutf2	100	93.701	Paramormyrops_kingsleyae
ENSG00000102898	NUTF2	100	77.953	ENSPKIG00000002859	nutf2l	99	77.953	Paramormyrops_kingsleyae
ENSG00000102898	NUTF2	100	74.016	ENSPSIG00000005184	-	100	74.016	Pelodiscus_sinensis
ENSG00000102898	NUTF2	100	92.126	ENSPSIG00000008982	NUTF2	100	92.126	Pelodiscus_sinensis
ENSG00000102898	NUTF2	100	81.102	ENSPMGG00000017629	nutf2	100	81.102	Periophthalmus_magnuspinnatus
ENSG00000102898	NUTF2	100	62.963	ENSPMGG00000022947	-	98	62.992	Periophthalmus_magnuspinnatus
ENSG00000102898	NUTF2	93	47.475	ENSPMGG00000010031	-	91	44.348	Periophthalmus_magnuspinnatus
ENSG00000102898	NUTF2	100	100.000	ENSPEMG00000011558	-	100	100.000	Peromyscus_maniculatus_bairdii
ENSG00000102898	NUTF2	100	80.374	ENSPCIG00000005457	-	99	80.952	Phascolarctos_cinereus
ENSG00000102898	NUTF2	100	69.291	ENSPCIG00000019668	-	100	69.291	Phascolarctos_cinereus
ENSG00000102898	NUTF2	100	97.638	ENSPCIG00000028043	-	100	97.638	Phascolarctos_cinereus
ENSG00000102898	NUTF2	100	83.465	ENSPFOG00000007559	nutf2	100	83.465	Poecilia_formosa
ENSG00000102898	NUTF2	98	60.000	ENSPFOG00000014649	-	96	60.000	Poecilia_formosa
ENSG00000102898	NUTF2	98	60.000	ENSPLAG00000019086	-	96	60.000	Poecilia_latipinna
ENSG00000102898	NUTF2	100	83.465	ENSPLAG00000015382	nutf2	100	83.465	Poecilia_latipinna
ENSG00000102898	NUTF2	100	83.465	ENSPMEG00000005399	nutf2	100	83.465	Poecilia_mexicana
ENSG00000102898	NUTF2	99	59.813	ENSPMEG00000002550	-	96	60.800	Poecilia_mexicana
ENSG00000102898	NUTF2	98	60.000	ENSPREG00000008496	-	96	60.000	Poecilia_reticulata
ENSG00000102898	NUTF2	100	83.465	ENSPREG00000021485	nutf2	100	83.465	Poecilia_reticulata
ENSG00000102898	NUTF2	100	100.000	ENSPPYG00000007472	-	100	100.000	Pongo_abelii
ENSG00000102898	NUTF2	65	100.000	ENSPCAG00000015344	-	100	100.000	Procavia_capensis
ENSG00000102898	NUTF2	100	86.916	ENSPCOG00000021894	-	98	86.916	Propithecus_coquereli
ENSG00000102898	NUTF2	100	100.000	ENSPCOG00000013505	-	100	100.000	Propithecus_coquereli
ENSG00000102898	NUTF2	100	100.000	ENSPVAG00000016605	NUTF2	100	100.000	Pteropus_vampyrus
ENSG00000102898	NUTF2	100	87.402	ENSPNYG00000021965	nutf2	100	87.402	Pundamilia_nyererei
ENSG00000102898	NUTF2	97	58.065	ENSPNYG00000012053	-	95	58.065	Pundamilia_nyererei
ENSG00000102898	NUTF2	100	74.016	ENSPNAG00000022947	nutf2l	99	74.016	Pygocentrus_nattereri
ENSG00000102898	NUTF2	100	91.589	ENSPNAG00000017791	nutf2	100	91.339	Pygocentrus_nattereri
ENSG00000102898	NUTF2	100	100.000	ENSRNOG00000018945	Nutf2	100	100.000	Rattus_norvegicus
ENSG00000102898	NUTF2	100	100.000	ENSRBIG00000023161	-	100	100.000	Rhinopithecus_bieti
ENSG00000102898	NUTF2	100	99.213	ENSRBIG00000029281	-	100	99.213	Rhinopithecus_bieti
ENSG00000102898	NUTF2	91	85.217	ENSRBIG00000028302	-	100	85.217	Rhinopithecus_bieti
ENSG00000102898	NUTF2	91	85.217	ENSRROG00000031012	-	100	85.217	Rhinopithecus_roxellana
ENSG00000102898	NUTF2	100	100.000	ENSRROG00000038445	-	100	100.000	Rhinopithecus_roxellana
ENSG00000102898	NUTF2	99	83.333	ENSRROG00000042524	-	99	83.333	Rhinopithecus_roxellana
ENSG00000102898	NUTF2	91	44.444	YER009W	-	94	44.444	Saccharomyces_cerevisiae
ENSG00000102898	NUTF2	100	100.000	ENSSBOG00000031335	-	100	100.000	Saimiri_boliviensis_boliviensis
ENSG00000102898	NUTF2	100	97.638	ENSSHAG00000006100	NUTF2	100	97.638	Sarcophilus_harrisii
ENSG00000102898	NUTF2	100	69.291	ENSSHAG00000003834	-	100	69.291	Sarcophilus_harrisii
ENSG00000102898	NUTF2	100	91.339	ENSSFOG00015014337	nutf2	100	91.339	Scleropages_formosus
ENSG00000102898	NUTF2	100	75.701	ENSSFOG00015004947	nutf2l	99	74.803	Scleropages_formosus
ENSG00000102898	NUTF2	100	93.701	ENSSFOG00015010919	nutf2	100	93.701	Scleropages_formosus
ENSG00000102898	NUTF2	98	57.937	ENSSMAG00000007431	-	98	57.937	Scophthalmus_maximus
ENSG00000102898	NUTF2	93	77.778	ENSSMAG00000015346	nutf2	94	69.027	Scophthalmus_maximus
ENSG00000102898	NUTF2	100	87.402	ENSSDUG00000020273	nutf2	100	87.402	Seriola_dumerili
ENSG00000102898	NUTF2	97	58.871	ENSSDUG00000011577	-	95	58.871	Seriola_dumerili
ENSG00000102898	NUTF2	97	58.871	ENSSLDG00000013801	-	95	58.871	Seriola_lalandi_dorsalis
ENSG00000102898	NUTF2	100	87.402	ENSSLDG00000013850	nutf2	100	87.402	Seriola_lalandi_dorsalis
ENSG00000102898	NUTF2	69	97.297	ENSSARG00000007472	NUTF2	100	97.403	Sorex_araneus
ENSG00000102898	NUTF2	100	91.589	ENSSPUG00000002988	NUTF2	99	88.800	Sphenodon_punctatus
ENSG00000102898	NUTF2	97	58.065	ENSSPAG00000019662	-	95	58.065	Stegastes_partitus
ENSG00000102898	NUTF2	100	87.402	ENSSPAG00000016834	nutf2	100	87.402	Stegastes_partitus
ENSG00000102898	NUTF2	100	99.213	ENSSSCG00000030295	-	100	99.213	Sus_scrofa
ENSG00000102898	NUTF2	100	60.630	ENSSSCG00000040724	-	100	60.630	Sus_scrofa
ENSG00000102898	NUTF2	91	76.522	ENSSSCG00000036599	-	100	76.522	Sus_scrofa
ENSG00000102898	NUTF2	100	96.063	ENSTGUG00000005301	NUTF2	100	96.063	Taeniopygia_guttata
ENSG00000102898	NUTF2	95	75.207	ENSTRUG00000023118	nutf2	93	74.194	Takifugu_rubripes
ENSG00000102898	NUTF2	95	75.207	ENSTNIG00000004846	nutf2	92	75.207	Tetraodon_nigroviridis
ENSG00000102898	NUTF2	100	88.189	ENSTBEG00000012586	-	100	88.189	Tupaia_belangeri
ENSG00000102898	NUTF2	74	100.000	ENSTBEG00000011016	NUTF2	100	100.000	Tupaia_belangeri
ENSG00000102898	NUTF2	100	100.000	ENSTTRG00000009251	NUTF2	100	100.000	Tursiops_truncatus
ENSG00000102898	NUTF2	100	100.000	ENSUAMG00000021046	-	100	100.000	Ursus_americanus
ENSG00000102898	NUTF2	100	78.740	ENSUAMG00000017217	-	62	78.740	Ursus_americanus
ENSG00000102898	NUTF2	100	77.953	ENSUMAG00000014652	-	62	77.953	Ursus_maritimus
ENSG00000102898	NUTF2	100	100.000	ENSUMAG00000019576	-	100	100.000	Ursus_maritimus
ENSG00000102898	NUTF2	100	100.000	ENSVPAG00000004417	NUTF2	100	100.000	Vicugna_pacos
ENSG00000102898	NUTF2	100	94.393	ENSVVUG00000007528	-	79	95.238	Vulpes_vulpes
ENSG00000102898	NUTF2	100	100.000	ENSVVUG00000012627	-	100	100.000	Vulpes_vulpes
ENSG00000102898	NUTF2	100	89.764	ENSVVUG00000000653	-	100	89.764	Vulpes_vulpes
ENSG00000102898	NUTF2	100	95.327	ENSVVUG00000026631	-	100	94.488	Vulpes_vulpes
ENSG00000102898	NUTF2	100	97.638	ENSVVUG00000019079	-	100	97.638	Vulpes_vulpes
ENSG00000102898	NUTF2	100	88.189	ENSXETG00000026897	nutf2	100	88.189	Xenopus_tropicalis
ENSG00000102898	NUTF2	74	87.234	ENSXCOG00000007675	nutf2	90	87.234	Xiphophorus_couchianus
ENSG00000102898	NUTF2	98	60.000	ENSXCOG00000020054	-	96	60.000	Xiphophorus_couchianus
ENSG00000102898	NUTF2	98	60.000	ENSXMAG00000003659	-	96	60.000	Xiphophorus_maculatus
ENSG00000102898	NUTF2	100	68.504	ENSXMAG00000005770	nutf2	100	68.504	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0005515	protein binding	7744965.18266911.19098896.24855949.25416956.	IPI	Function
GO:0005637	nuclear inner membrane	-	IEA	Component
GO:0005640	nuclear outer membrane	-	IEA	Component
GO:0005654	nucleoplasm	10679025.	IDA	Component
GO:0005829	cytosol	7744965.10679025.	IDA	Component
GO:0006606	protein import into nucleus	21873635.	IBA	Process
GO:0006606	protein import into nucleus	7744965.10679025.	IDA	Process
GO:0006611	protein export from nucleus	16449645.	IDA	Process
GO:0006913	nucleocytoplasmic transport	21873635.	IBA	Process
GO:0008536	Ran GTPase binding	10679025.	IDA	Function
GO:0008536	Ran GTPase binding	18266911.	IPI	Function
GO:0008565	protein transporter activity	21873635.	IBA	Function
GO:0017056	structural constituent of nuclear pore	7744965.10679025.	IDA	Function
GO:0031965	nuclear membrane	-	ISS	Component
GO:0042802	identical protein binding	19098896.25416956.	IPI	Function
GO:0044613	nuclear pore central transport channel	21873635.	IBA	Component
GO:0051028	mRNA transport	-	IEA	Process
GO:0070062	extracellular exosome	20458337.23533145.	HDA	Component
GO:0090204	protein localization to nuclear pore	-	ISS	Process

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
BLCA	chr16	67870806	Nonsense_Mutation	novel	E93*	0.33	NTF2
BLCA	chr16	67865197	Missense_Mutation	NA	D23H	0.4	NTF2
BRCA	chr16	67868538	Missense_Mutation	NA	A70V	0.46	NTF2
BRCA	chr16	67870783	Intron	novel		0.43
BRCA	chr16	67868348	Silent	rs750611785	A36A	0.86
BRCA	chr16	67870717	Intron	novel		0.36
CESC	chr16	67865123	5'UTR	rs764467329		0.45
CESC	chr16	67868660	Intron	novel		0.09
CESC	chr16	67870761	Intron	NA		0.5
CESC	chr16	67870922	3'UTR	NA		0.3
CESC	chr16	67868350	Missense_Mutation	NA	S37L	0.19	NTF2
CESC	chr16	67868533	Silent	NA	I68I	0.17
CESC	chr16	67865157	Missense_Mutation	novel	Q9H	0.47
CHOL	chr16	67871278	3'UTR	novel		0.13
COAD	chr16	67870788	Intron	novel		0.3
COAD	chr16	67868461	Intron	novel		0.34
COAD	chr16	67870856	Silent	rs567238959	N109N	0.44
COAD	chr16	67870717	Intron	novel		0.14
COAD	chr16	67868433	Intron	novel		0.12
COAD	chr16	67868509	Silent	novel	P60P	0.05
COAD	chr16	67870718	Intron	novel		0.17
COAD	chr16	67865230	Splice_Site	NA	X33_splice	0.15
COAD	chr16	67868615	Intron	novel		0.21
GBM	chr16	67868726	Intron	novel		0.64
HNSC	chr16	67865203	Missense_Mutation	novel	D25H	0.13	NTF2
KIRC	chr16	67868624	Intron	novel		0.26
LIHC	chr16	67868592	Missense_Mutation	novel	Q88L	0.54	NTF2
LUAD	chr16	67865221	Missense_Mutation	NA	A31P	0.25	NTF2
LUSC	chr16	67870761	Intron	novel		0.12
LUSC	chr16	67870838	Silent	novel	F103F	0.37
LUSC	chr16	67870688	Intron	novel		0.48
LUSC	chr16	67868482	Intron	novel		0.07
OV	chr16	67868581	Frame_Shift_Ins	novel	*V85Sfs6**	0.13	NTF2
OV	chr16	67868671	Intron	novel		0.1
OV	chr16	67870901	Silent	novel	H124H	0.11
OV	chr16	67868597	Frame_Shift_Ins	novel	*K90Tfs24**	0.03	NTF2
PAAD	chr16	67870893	Missense_Mutation	rs201657691	A122T	0.04
PRAD	chr16	67865221	Missense_Mutation	novel	A31T	0.41	NTF2
READ	chr16	67871019	3'UTR	rs550044079		0.25
READ	chr16	67870936	3'UTR	rs551980046		0.36
SKCM	chr16	67868378	Silent	rs755127384	F46F	0.44
SKCM	chr16	67870735	Intron	novel		0.29
SKCM	chr16	67870628	Intron	novel		1
SKCM	chr16	67870792	Splice_Region	novel		0.18
STAD	chr16	67870909	Missense_Mutation	NA	G127D	0.24
STAD	chr16	67868537	Missense_Mutation	NA	A70T	0.28	NTF2
STAD	chr16	67865222	Missense_Mutation	NA	A31V	0.15	NTF2
STAD	chr16	67868369	Silent	NA	G43G	0.21
STAD	chr16	67868488	Intron	novel		0.3
THCA	chr16	67868659	Intron	novel		0.06
UCEC	chr16	67868439	Intron	novel		0.42
UCEC	chr16	67870942	3'UTR	novel		0.33
UCEC	chr16	67868539	Silent	rs140700348	A70A	0.46
UCEC	chr16	67870576	Intron	novel		1
UCEC	chr16	67870788	Intron	novel		0.26
UCEC	chr16	67870613	Intron	novel		0.47
UCEC	chr16	67871308	3'UTR	novel		0.4
UCEC	chr16	67870783	Intron	novel		0.57
UCEC	chr16	67868347	Missense_Mutation	rs780123868	A36V	0.13	NTF2
UCEC	chr16	67870937	3'UTR	rs778608707		0.26
UCEC	chr16	67870718	Intron	novel		0.42
UCEC	chr16	67870718	Intron	novel		0.42
UCEC	chr16	67868538	Missense_Mutation	NA	A70V	0.33	NTF2
UCEC	chr16	67871122	3'UTR	novel		0.1
UCEC	chr16	67871304	3'UTR	novel		0.13
UCEC	chr16	67870937	3'UTR	rs778608707		0.25
UCEC	chr16	67868616	Intron	novel		0.26
UCEC	chr16	67868359	Missense_Mutation	novel	T40M	0.21	NTF2
UCEC	chr16	67868765	Intron	novel		0.22
UCEC	chr16	67870587	Intron	novel		0.25
UCEC	chr16	67871303	3'UTR	novel		0.4
UCEC	chr16	67865203	Missense_Mutation	novel	D25Y	0.38	NTF2
UCS	chr16	67865221	Missense_Mutation	novel	A31T	0.33	NTF2

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
BLCA	AMP	0.1936	0.063591
CHOL	DEL	0.1667	0.23475
LAML	DEL	0.0314	0.0010312
OV	DEL	0.7582	1.5979e-14
TGCT	AMP	0.12	0.035574
UCEC	DEL	0.282	4.7164e-05

Survival Analysis

Cancer	P-value	Q-value
THYM	0.0075	Kaplan-Meier Survival Analysis
SARC	0.035	Kaplan-Meier Survival Analysis
MESO	0.00025	Kaplan-Meier Survival Analysis
ACC	0.00031	Kaplan-Meier Survival Analysis
HNSC	0.00092	Kaplan-Meier Survival Analysis
SKCM	0.001	Kaplan-Meier Survival Analysis
LUSC	0.05	Kaplan-Meier Survival Analysis
PAAD	0.0062	Kaplan-Meier Survival Analysis
KICH	0.0075	Kaplan-Meier Survival Analysis
UCEC	0.0094	Kaplan-Meier Survival Analysis
LIHC	0.0018	Kaplan-Meier Survival Analysis
LUAD	0.0083	Kaplan-Meier Survival Analysis
OV	0.02	Kaplan-Meier Survival Analysis

Drugs

EuRBPDB

Description

RBDs

Literatures

Expression

Transcripts

Gene Model

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742