EuRBPDB

Basic Information
Cancer Related Information

Description

RBDs

Expression

Transcripts

Gene Model

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000102935 (Gene tree)
Gene ID: 23090
Gene Symbol: ZNF423
Alias: KIAA0760|OAZ|hOAZ|Ebfaz|Zfp104|NPHP14|JBTS19
Full Name: zinc finger protein 423
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Minus strand
Length: 370,396 bases
Position: chr16:49,487,524-49,857,919
Accession: 16762
RBP type: canonical RBP
Summary: The protein encoded by this gene is a nuclear protein that belongs to the family of Kruppel-like C2H2 zinc finger proteins. It functions as a DNA-binding transcription factor by using distinct zinc fingers in different signaling pathways. Thus, it is thought that this gene may have multiple roles in signal transduction during development. Mutations in this gene are associated with nephronophthisis-14 and Joubert syndrome-19. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2012]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000455588	zf-C2H2	PF00096.26	4.2e-57	1	6
ENSP00000455588	zf-C2H2	PF00096.26	4.2e-57	2	6
ENSP00000455588	zf-C2H2	PF00096.26	4.2e-57	3	6
ENSP00000455588	zf-C2H2	PF00096.26	4.2e-57	4	6
ENSP00000455588	zf-C2H2	PF00096.26	4.2e-57	5	6
ENSP00000455588	zf-C2H2	PF00096.26	4.2e-57	6	6
ENSP00000457664	zf-C2H2	PF00096.26	4.2e-57	1	6
ENSP00000457664	zf-C2H2	PF00096.26	4.2e-57	2	6
ENSP00000457664	zf-C2H2	PF00096.26	4.2e-57	3	6
ENSP00000457664	zf-C2H2	PF00096.26	4.2e-57	4	6
ENSP00000457664	zf-C2H2	PF00096.26	4.2e-57	5	6
ENSP00000457664	zf-C2H2	PF00096.26	4.2e-57	6	6
ENSP00000457928	zf-C2H2	PF00096.26	4.2e-57	1	6
ENSP00000457928	zf-C2H2	PF00096.26	4.2e-57	2	6
ENSP00000457928	zf-C2H2	PF00096.26	4.2e-57	3	6
ENSP00000457928	zf-C2H2	PF00096.26	4.2e-57	4	6
ENSP00000457928	zf-C2H2	PF00096.26	4.2e-57	5	6
ENSP00000457928	zf-C2H2	PF00096.26	4.2e-57	6	6
ENSP00000262383	zf-C2H2	PF00096.26	1.9e-56	1	6
ENSP00000262383	zf-C2H2	PF00096.26	1.9e-56	2	6
ENSP00000262383	zf-C2H2	PF00096.26	1.9e-56	3	6
ENSP00000262383	zf-C2H2	PF00096.26	1.9e-56	4	6
ENSP00000262383	zf-C2H2	PF00096.26	1.9e-56	5	6
ENSP00000262383	zf-C2H2	PF00096.26	1.9e-56	6	6
ENSP00000455426	zf-C2H2	PF00096.26	1.9e-56	1	6
ENSP00000455426	zf-C2H2	PF00096.26	1.9e-56	2	6
ENSP00000455426	zf-C2H2	PF00096.26	1.9e-56	3	6
ENSP00000455426	zf-C2H2	PF00096.26	1.9e-56	4	6
ENSP00000455426	zf-C2H2	PF00096.26	1.9e-56	5	6
ENSP00000455426	zf-C2H2	PF00096.26	1.9e-56	6	6
ENSP00000442321	zf-C2H2	PF00096.26	4.8e-56	1	6
ENSP00000442321	zf-C2H2	PF00096.26	4.8e-56	2	6
ENSP00000442321	zf-C2H2	PF00096.26	4.8e-56	3	6
ENSP00000442321	zf-C2H2	PF00096.26	4.8e-56	4	6
ENSP00000442321	zf-C2H2	PF00096.26	4.8e-56	5	6
ENSP00000442321	zf-C2H2	PF00096.26	4.8e-56	6	6
ENSP00000455061	zf-C2H2	PF00096.26	4.8e-56	1	6
ENSP00000455061	zf-C2H2	PF00096.26	4.8e-56	2	6
ENSP00000455061	zf-C2H2	PF00096.26	4.8e-56	3	6
ENSP00000455061	zf-C2H2	PF00096.26	4.8e-56	4	6
ENSP00000455061	zf-C2H2	PF00096.26	4.8e-56	5	6
ENSP00000455061	zf-C2H2	PF00096.26	4.8e-56	6	6
ENSP00000442321	zf-met	PF12874.7	0.00066	1	3
ENSP00000442321	zf-met	PF12874.7	0.00066	2	3
ENSP00000442321	zf-met	PF12874.7	0.00066	3	3
ENSP00000455061	zf-met	PF12874.7	0.00066	1	3
ENSP00000455061	zf-met	PF12874.7	0.00066	2	3
ENSP00000455061	zf-met	PF12874.7	0.00066	3	3
ENSP00000455588	zf-met	PF12874.7	0.00095	1	3
ENSP00000455588	zf-met	PF12874.7	0.00095	2	3
ENSP00000455588	zf-met	PF12874.7	0.00095	3	3
ENSP00000457664	zf-met	PF12874.7	0.00095	1	3
ENSP00000457664	zf-met	PF12874.7	0.00095	2	3
ENSP00000457664	zf-met	PF12874.7	0.00095	3	3
ENSP00000457928	zf-met	PF12874.7	0.00095	1	3
ENSP00000457928	zf-met	PF12874.7	0.00095	2	3
ENSP00000457928	zf-met	PF12874.7	0.00095	3	3
ENSP00000262383	zf-met	PF12874.7	0.0014	1	3
ENSP00000262383	zf-met	PF12874.7	0.0014	2	3
ENSP00000262383	zf-met	PF12874.7	0.0014	3	3
ENSP00000455426	zf-met	PF12874.7	0.0014	1	3
ENSP00000455426	zf-met	PF12874.7	0.0014	2	3
ENSP00000455426	zf-met	PF12874.7	0.0014	3	3

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000562871	ZNF423-205	4514	XM_005255856	ENSP00000457928	1224 (aa)	XP_005255913	Q2M1K9
ENST00000535559	ZNF423-202	4201	-	ENSP00000442321	1167 (aa)	-	F5H7S1
ENST00000567169	ZNF423-207	4017	-	ENSP00000455061	1167 (aa)	-	F5H7S1
ENST00000562520	ZNF423-204	4018	-	ENSP00000457664	1224 (aa)	-	Q2M1K9
ENST00000262383	ZNF423-201	4578	XM_017023076	ENSP00000262383	1284 (aa)	XP_016878565	Q2M1K9
ENST00000561648	ZNF423-203	7907	XM_006721171	ENSP00000455426	1284 (aa)	XP_006721234	Q2M1K9
ENST00000568094	ZNF423-208	456	-	ENSP00000479288	102 (aa)	-	A0A087WV99
ENST00000563137	ZNF423-206	4911	XM_017023077	ENSP00000455588	1224 (aa)	XP_016878566	Q2M1K9

Gene Model

Click here to download ENSG00000102935's gene model file

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000102935	Fibrinogen	5.7490000E-005	-
ENSG00000102935	Cell Adhesion Molecules	9.8620000E-006	-
ENSG00000102935	Cell Adhesion Molecules	8.2910000E-005	-
ENSG00000102935	Cell Adhesion Molecules	9.7140000E-005	-
ENSG00000102935	Erythrocyte Count	2.2020000E-005	-
ENSG00000102935	Leukoaraiosis	9.5010925E-005	-
ENSG00000102935	Asthma	4.1398350E-005	-
ENSG00000102935	Platelet Function Tests	7.4154449E-006	-
ENSG00000102935	Platelet Function Tests	4.4408920E-015	-
ENSG00000102935	Receptors, Transferrin	2.7460000E-005	-
ENSG00000102935	Behavior	3E-6	18821565
ENSG00000102935	Cannabis	6E-6	25987507
ENSG00000102935	Age of Onset	6E-6	25987507
ENSG00000102935	Immunoglobulins	4E-6	23382691
ENSG00000102935	Body Mass Index	4E-6	25673412
ENSG00000102935	Waist-Hip Ratio	4E-6	25673412
ENSG00000102935	Body Mass Index	6E-6	25673412
ENSG00000102935	Waist-Hip Ratio	6E-6	25673412
ENSG00000102935	Immunoglobulins	4E-6	23382691
ENSG00000102935	Body Mass Index	5E-7	25673412
ENSG00000102935	Waist Circumference	5E-7	25673412
ENSG00000102935	Body Mass Index	5E-8	25673412
ENSG00000102935	Waist Circumference	5E-8	25673412
ENSG00000102935	Immunoglobulins	5E-6	23382691

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000102935	rs141854787	16	49752347	T	Cannabis use (age at onset)	25987507	[0.21-0.49] unit increase	0.35	EFO_0007585\|EFO_0004847
ENSG00000102935	rs16944158	16	49618868	G	IgG glycosylation	23382691	[0.093-0.231] unit decrease	0.162	EFO_0005193
ENSG00000102935	rs2080501	16	49609655	G	IgG glycosylation	23382691	[0.082-0.203] unit increase	0.1421	EFO_0005193
ENSG00000102935	rs2080501	16	49609655	G	IgG glycosylation	23382691	[0.081-0.201] unit decrease	0.141	EFO_0005193
ENSG00000102935	rs17281813	16	49716879	?	Inattentive symptoms	18821565			GO_0007610
ENSG00000102935	rs72793523	16	49557061	G	Mosquito bite size	28199695	[0.018-0.046] unit increase	0.0324662	EFO_0008378
ENSG00000102935	rs7197830	16	49755426	A	Self-reported math ability	30038396	[0.0079-0.0157] unit increase	0.0118	EFO_0004875
ENSG00000102935	rs4785187	16	49732861	A	Educational attainment (MTAG)	30038396	[0.0067-0.0129] unit decrease	0.0098	EFO_0004784
ENSG00000102935	rs7197830	16	49755426	A	Self-reported math ability (MTAG)	30038396	[0.0075-0.0149] unit increase	0.0112	EFO_0004875
ENSG00000102935	rs7403957	16	49775652	A	Highest math class taken (MTAG)	30038396	[0.0078-0.0144] unit increase	0.0111	EFO_0004875
ENSG00000102935	rs2047937	16	49830880	T	Waist circumference adjusted for body mass index	25673412	[0.013-0.03] unit decrease	0.0218	EFO_0007789
ENSG00000102935	rs2047937	16	49830880	T	Waist circumference adjusted for body mass index	25673412	[0.012-0.025] unit decrease	0.0186	EFO_0007789
ENSG00000102935	rs2047937	16	49830880	C	Waist-to-hip ratio adjusted for body mass index	25673412	[0.0092-0.0226] unit increase	0.0159	EFO_0007788
ENSG00000102935	rs2047937	16	49830880	C	Waist-to-hip ratio adjusted for body mass index	25673412	[0.0085-0.0215] unit increase	0.015	EFO_0007788
ENSG00000102935	rs2047937	16	49830880	T	Waist circumference adjusted for BMI in non-smokers	28443625	[0.012-0.027] unit decrease	0.0192	EFO_0007789
ENSG00000102935	rs2047937	16	49830880	T	Waist circumference adjusted for BMI (adjusted for smoking behaviour)	28443625	[0.011-0.024] unit decrease	0.0176	EFO_0004318\|EFO_0007789
ENSG00000102935	rs2047937	16	49830880	T	Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction)	28443625			EFO_0004318\|EFO_0007789
ENSG00000102935	rs933561	16	49840765	?	Heel bone mineral density	30048462	[0.012-0.021] unit increase	0.0163967	EFO_0009270
ENSG00000102935	rs9921634	16	49488523	?	Adolescent idiopathic scoliosis	30019117			EFO_0005423
ENSG00000102935	rs4785187	16	49732861	A	Educational attainment (years of education)	30038396	[0.0067-0.0133] unit decrease	0.01	EFO_0004784
ENSG00000102935	rs34294937	16	49850016	A	Systolic blood pressure	30578418	[0.14-0.27] mmHg increase	0.2079	EFO_0006335
ENSG00000102935	rs933561	16	49840765	A	Heel bone mineral density	30598549	[0.01-0.018] unit increase	0.0141303	EFO_0009270
ENSG00000102935	rs1468869	16	49831647	?	Balding type 1	30595370			EFO_0007825
ENSG00000102935	rs34294937	16	49850016	A	Male-pattern baldness	30573740	[0.015-0.03] unit decrease	0.0225411	EFO_0007825
ENSG00000102935	rs55942317	16	49592861	A	Number of sexual partners	30643258	[0.021-0.037] unit increase	0.029158004	EFO_0007877
ENSG00000102935	rs7404754	16	49734010	?	Systolic blood pressure	30595370			EFO_0006335
ENSG00000102935	rs34050011	16	49834602	?	Waist-hip ratio	30595370			EFO_0004343
ENSG00000102935	rs28633718	16	49850619	?	White blood cell count	30595370			EFO_0004308
ENSG00000102935	rs752894	16	49735725	?	Smoking status	30595370			EFO_0006527
ENSG00000102935	rs10468291	16	49734135	C	Diastolic blood pressure	30224653	[0.082-0.151] mmHg increase	0.1166	EFO_0006336
ENSG00000102935	rs6500257	16	49790986	A	Age of smoking initiation (MTAG)	30643251	[0.0067-0.0125] unit decrease	0.00959681	EFO_0005670
ENSG00000102935	rs55942317	16	49592861	A	Risk-taking tendency (4-domain principal component model)	30643258	[0.016-0.033] unit increase	0.024579043	EFO_0008579
ENSG00000102935	rs56295507	16	49698075	G	Word spelling	30741946	[0.084-0.214] unit increase	0.148834	EFO_0005301
ENSG00000102935	rs1876001	16	49844028	?	Heel bone mineral density	30595370			EFO_0009270
ENSG00000102935	rs76796131	16	49533110	T	Smoking initiation (ever regular vs never regular) (MTAG)	30643251	[0.013-0.024] unit increase	0.0186652	EFO_0006527
ENSG00000102935	rs6500257	16	49790986	A	Smoking initiation (ever regular vs never regular) (MTAG)	30643251	[0.0063-0.0106] unit increase	0.00845886	EFO_0006527
ENSG00000102935	rs4785187	16	49732861	A	Smoking initiation (ever regular vs never regular)	30643251	[0.014-0.026] unit increase	0.01997724	EFO_0006527

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000102935's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000102935	ZNF423	100	98.715	ENSAMEG00000006481	ZNF423	100	98.593	Ailuropoda_melanoleuca
ENSG00000102935	ZNF423	99	77.227	ENSAOCG00000019850	si:ch211-216l23.1	98	77.778	Amphiprion_ocellaris
ENSG00000102935	ZNF423	99	77.333	ENSAPEG00000022511	si:ch211-216l23.1	99	77.627	Amphiprion_percula
ENSG00000102935	ZNF423	99	92.564	ENSAPLG00000009508	ZNF423	99	92.720	Anas_platyrhynchos
ENSG00000102935	ZNF423	100	91.631	ENSACAG00000013803	ZNF423	99	91.722	Anolis_carolinensis
ENSG00000102935	ZNF423	100	99.510	ENSANAG00000026460	ZNF423	100	99.455	Aotus_nancymaae
ENSG00000102935	ZNF423	100	98.972	ENSBTAG00000017397	ZNF423	100	98.972	Bos_taurus
ENSG00000102935	ZNF423	100	99.428	ENSCJAG00000011975	ZNF423	100	99.428	Callithrix_jacchus
ENSG00000102935	ZNF423	100	98.129	ENSCAFG00020000541	ZNF423	100	98.129	Canis_lupus_dingo
ENSG00000102935	ZNF423	100	98.972	ENSCHIG00000027139	ZNF423	99	98.750	Capra_hircus
ENSG00000102935	ZNF423	99	98.014	ENSTSYG00000027307	ZNF423	98	98.014	Carlito_syrichta
ENSG00000102935	ZNF423	100	98.886	ENSCAPG00000014613	ZNF423	99	98.809	Cavia_aperea
ENSG00000102935	ZNF423	100	98.886	ENSCPOG00000000162	ZNF423	100	98.886	Cavia_porcellus
ENSG00000102935	ZNF423	100	99.143	ENSCCAG00000009645	ZNF423	100	98.832	Cebus_capucinus
ENSG00000102935	ZNF423	100	99.510	ENSCATG00000034661	ZNF423	100	99.486	Cercocebus_atys
ENSG00000102935	ZNF423	100	98.800	ENSCLAG00000007342	ZNF423	100	98.800	Chinchilla_lanigera
ENSG00000102935	ZNF423	100	99.428	ENSCSAG00000005405	ZNF423	100	99.377	Chlorocebus_sabaeus
ENSG00000102935	ZNF423	100	92.997	ENSCPBG00000015985	ZNF423	100	90.996	Chrysemys_picta_bellii
ENSG00000102935	ZNF423	100	99.486	ENSCANG00000030345	ZNF423	100	99.496	Colobus_angolensis_palliatus
ENSG00000102935	ZNF423	100	98.366	ENSCGRG00001023063	Zfp423	99	98.332	Cricetulus_griseus_chok1gshd
ENSG00000102935	ZNF423	100	98.366	ENSCGRG00000016739	Zfp423	100	98.286	Cricetulus_griseus_crigri
ENSG00000102935	ZNF423	100	97.386	ENSDNOG00000038075	ZNF423	100	97.386	Dasypus_novemcinctus
ENSG00000102935	ZNF423	100	99.020	ENSDORG00000023772	Zfp423	100	98.972	Dipodomys_ordii
ENSG00000102935	ZNF423	100	98.203	ENSEASG00005014542	ZNF423	99	97.891	Equus_asinus_asinus
ENSG00000102935	ZNF423	100	98.366	ENSECAG00000000244	ZNF423	99	98.047	Equus_caballus
ENSG00000102935	ZNF423	100	99.143	ENSFCAG00000012158	ZNF423	100	99.143	Felis_catus
ENSG00000102935	ZNF423	100	98.856	ENSFDAG00000012603	ZNF423	99	96.698	Fukomys_damarensis
ENSG00000102935	ZNF423	99	71.476	ENSGMOG00000012893	si:ch211-216l23.1	100	72.735	Gadus_morhua
ENSG00000102935	ZNF423	100	93.168	ENSGALG00000003891	ZNF423	99	93.311	Gallus_gallus
ENSG00000102935	ZNF423	99	72.681	ENSGACG00000002626	si:ch211-216l23.1	100	73.383	Gasterosteus_aculeatus
ENSG00000102935	ZNF423	100	99.844	ENSGGOG00000016641	ZNF423	100	99.844	Gorilla_gorilla
ENSG00000102935	ZNF423	100	98.938	ENSHGLG00000007674	ZNF423	100	98.886	Heterocephalus_glaber_female
ENSG00000102935	ZNF423	100	98.938	ENSHGLG00100019441	ZNF423	100	98.938	Heterocephalus_glaber_male
ENSG00000102935	ZNF423	99	74.862	ENSHCOG00000016337	si:ch211-216l23.1	100	74.866	Hippocampus_comes
ENSG00000102935	ZNF423	100	98.611	ENSSTOG00000028569	ZNF423	100	98.543	Ictidomys_tridecemlineatus
ENSG00000102935	ZNF423	100	98.284	ENSJJAG00000019328	Zfp423	100	98.201	Jaculus_jaculus
ENSG00000102935	ZNF423	99	70.638	ENSKMAG00000006327	si:ch211-216l23.1	99	68.750	Kryptolebias_marmoratus
ENSG00000102935	ZNF423	100	88.908	ENSLACG00000012406	ZNF423	99	88.142	Latimeria_chalumnae
ENSG00000102935	ZNF423	100	96.650	ENSLAFG00000018386	ZNF423	100	96.661	Loxodonta_africana
ENSG00000102935	ZNF423	100	99.510	ENSMFAG00000045032	ZNF423	99	99.375	Macaca_fascicularis
ENSG00000102935	ZNF423	100	99.510	ENSMMUG00000021261	ZNF423	100	99.486	Macaca_mulatta
ENSG00000102935	ZNF423	100	99.428	ENSMNEG00000007103	ZNF423	96	97.932	Macaca_nemestrina
ENSG00000102935	ZNF423	100	99.510	ENSMLEG00000041391	ZNF423	100	99.486	Mandrillus_leucophaeus
ENSG00000102935	ZNF423	99	73.410	ENSMAMG00000016634	si:ch211-216l23.1	98	73.696	Mastacembelus_armatus
ENSG00000102935	ZNF423	100	92.485	ENSMGAG00000005058	ZNF423	100	92.726	Meleagris_gallopavo
ENSG00000102935	ZNF423	100	98.448	ENSMAUG00000015448	Zfp423	100	98.372	Mesocricetus_auratus
ENSG00000102935	ZNF423	100	99.183	ENSMICG00000005195	ZNF423	100	99.183	Microcebus_murinus
ENSG00000102935	ZNF423	100	98.366	ENSMOCG00000002689	Zfp423	100	98.279	Microtus_ochrogaster
ENSG00000102935	ZNF423	98	75.696	ENSMMOG00000002619	si:ch211-216l23.1	96	74.881	Mola_mola
ENSG00000102935	ZNF423	100	98.286	MGP_CAROLIEiJ_G0031352	Zfp423	99	98.253	Mus_caroli
ENSG00000102935	ZNF423	100	98.372	ENSMUSG00000045333	Zfp423	100	98.372	Mus_musculus
ENSG00000102935	ZNF423	100	98.121	MGP_PahariEiJ_G0022953	Zfp423	99	97.812	Mus_pahari
ENSG00000102935	ZNF423	100	98.372	MGP_SPRETEiJ_G0032470	Zfp423	99	98.332	Mus_spretus
ENSG00000102935	ZNF423	100	98.800	ENSMPUG00000003075	ZNF423	100	98.775	Mustela_putorius_furo
ENSG00000102935	ZNF423	99	95.057	ENSMLUG00000009878	ZNF423	100	94.995	Myotis_lucifugus
ENSG00000102935	ZNF423	100	97.943	ENSNGAG00000022025	Zfp423	100	97.943	Nannospalax_galili
ENSG00000102935	ZNF423	100	99.755	ENSNLEG00000000697	ZNF423	100	99.688	Nomascus_leucogenys
ENSG00000102935	ZNF423	100	98.972	ENSODEG00000002057	ZNF423	100	98.972	Octodon_degus
ENSG00000102935	ZNF423	100	98.629	ENSOCUG00000003685	ZNF423	99	98.411	Oryctolagus_cuniculus
ENSG00000102935	ZNF423	98	76.890	ENSORLG00000013673	si:ch211-216l23.1	98	77.485	Oryzias_latipes
ENSG00000102935	ZNF423	99	76.962	ENSORLG00020017076	si:ch211-216l23.1	98	77.389	Oryzias_latipes_hni
ENSG00000102935	ZNF423	98	76.825	ENSORLG00015007270	si:ch211-216l23.1	98	77.060	Oryzias_latipes_hsok
ENSG00000102935	ZNF423	99	73.896	ENSOMEG00000000376	si:ch211-216l23.1	97	75.365	Oryzias_melastigma
ENSG00000102935	ZNF423	99	98.977	ENSOGAG00000029813	ZNF423	100	98.977	Otolemur_garnettii
ENSG00000102935	ZNF423	100	99.922	ENSPPAG00000038999	ZNF423	100	99.922	Pan_paniscus
ENSG00000102935	ZNF423	100	99.143	ENSPPRG00000019601	ZNF423	100	98.750	Panthera_pardus
ENSG00000102935	ZNF423	100	99.143	ENSPTIG00000008348	ZNF423	100	99.143	Panthera_tigris_altaica
ENSG00000102935	ZNF423	100	99.922	ENSPTRG00000008099	ZNF423	100	99.922	Pan_troglodytes
ENSG00000102935	ZNF423	100	99.510	ENSPANG00000022231	ZNF423	100	99.455	Papio_anubis
ENSG00000102935	ZNF423	100	98.366	ENSPEMG00000015523	Zfp423	100	98.286	Peromyscus_maniculatus_bairdii
ENSG00000102935	ZNF423	100	94.707	ENSPCIG00000021085	ZNF423	100	94.707	Phascolarctos_cinereus
ENSG00000102935	ZNF423	99	73.047	ENSPFOG00000003135	si:ch211-216l23.1	97	73.561	Poecilia_formosa
ENSG00000102935	ZNF423	99	70.970	ENSPMEG00000005904	si:ch211-216l23.1	97	71.572	Poecilia_mexicana
ENSG00000102935	ZNF423	100	99.837	ENSPPYG00000007334	ZNF423	100	99.837	Pongo_abelii
ENSG00000102935	ZNF423	99	99.028	ENSPCOG00000013159	ZNF423	100	98.826	Propithecus_coquereli
ENSG00000102935	ZNF423	100	98.629	ENSPVAG00000004835	ZNF423	100	98.627	Pteropus_vampyrus
ENSG00000102935	ZNF423	100	98.115	ENSRNOG00000014658	Zfp423	100	98.115	Rattus_norvegicus
ENSG00000102935	ZNF423	99	94.149	ENSRBIG00000040273	ZNF423	96	93.578	Rhinopithecus_bieti
ENSG00000102935	ZNF423	100	99.428	ENSRROG00000031311	ZNF423	100	99.428	Rhinopithecus_roxellana
ENSG00000102935	ZNF423	100	99.592	ENSSBOG00000029124	ZNF423	100	99.592	Saimiri_boliviensis_boliviensis
ENSG00000102935	ZNF423	99	89.430	ENSSHAG00000018342	ZNF423	100	89.668	Sarcophilus_harrisii
ENSG00000102935	ZNF423	99	73.115	ENSSDUG00000021415	si:ch211-216l23.1	99	73.241	Seriola_dumerili
ENSG00000102935	ZNF423	99	75.158	ENSSPAG00000018932	si:ch211-216l23.1	95	75.344	Stegastes_partitus
ENSG00000102935	ZNF423	100	99.265	ENSSSCG00000002838	ZNF423	100	99.265	Sus_scrofa
ENSG00000102935	ZNF423	99	70.804	ENSTRUG00000006180	si:ch211-216l23.1	97	71.224	Takifugu_rubripes
ENSG00000102935	ZNF423	99	75.560	ENSTNIG00000005047	si:ch211-216l23.1	100	75.560	Tetraodon_nigroviridis
ENSG00000102935	ZNF423	100	95.752	ENSTTRG00000000176	ZNF423	100	95.618	Tursiops_truncatus
ENSG00000102935	ZNF423	100	98.210	ENSVVUG00000018080	ZNF423	100	98.210	Vulpes_vulpes
ENSG00000102935	ZNF423	99	88.458	ENSXETG00000002339	znf423	100	88.448	Xenopus_tropicalis

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	-	ISA	Function
GO:0003677	DNA binding	21873635.	IBA	Function
GO:0003700	DNA-binding transcription factor activity	21873635.	IBA	Function
GO:0005515	protein binding	19345331.22863007.	IPI	Function
GO:0005634	nucleus	21873635.	IBA	Component
GO:0005634	nucleus	10660046.	IDA	Component
GO:0005654	nucleoplasm	-	IDA	Component
GO:0006355	regulation of transcription, DNA-templated	21873635.	IBA	Process
GO:0007219	Notch signaling pathway	-	ISS	Process
GO:0007399	nervous system development	-	IEA	Process
GO:0030154	cell differentiation	-	IEA	Process
GO:0030513	positive regulation of BMP signaling pathway	-	ISS	Process
GO:0045892	negative regulation of transcription, DNA-templated	10660046.	IDA	Process
GO:0045893	positive regulation of transcription, DNA-templated	10660046.	IDA	Process
GO:0046872	metal ion binding	-	IEA	Function
GO:0120163	negative regulation of cold-induced thermogenesis	27238639.	ISS	Process

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
28821270	Calmodulin-like protein 3 is an estrogen receptor alpha coregulator for gene expression and drug response in a SNP, estrogen, and SERM-dependent fashion.	Breast Cancer Res	2017 Aug 18	Qin S	doi: 10.1186/s13058-017-0890-x.

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
BLCA	chr16	49637776	Missense_Mutation	novel	H459R	0.21
BLCA	chr16	49730880	Missense_Mutation	novel	E56D	0.2
BLCA	chr16	49636071	Missense_Mutation	novel	Q1027H	0.1
BLCA	chr16	49525405	Missense_Mutation	novel	E1223Q	0.69
BLCA	chr16	49638459	Silent	NA	F231F	0.43
BLCA	chr16	49638728	Missense_Mutation	novel	F142L	0.71
BLCA	chr16	49636166	Missense_Mutation	novel	P996S	0.09
BLCA	chr16	49638530	Missense_Mutation	novel	H208N	0.22
BLCA	chr16	49626216	Missense_Mutation	novel	F1177L	0.2
BLCA	chr16	49637719	Missense_Mutation	NA	S478F	0.14
BLCA	chr16	49636160	Nonsense_Mutation	novel	Q998*	0.23
BLCA	chr16	49637954	Missense_Mutation	NA	D400N	0.41
BLCA	chr16	49638507	Silent	rs775209030	T215T	0.76
BLCA	chr16	49637078	Missense_Mutation	novel	Y692N	0.35
BLCA	chr16	49636823	Missense_Mutation	novel	P777T	0.1
BLCA	chr16	49637320	Missense_Mutation	NA	E611V	0.45
BLCA	chr16	49638611	Missense_Mutation	novel	R181C	0.51
BLCA	chr16	49638450	Silent	novel	T234T	0.37
BLCA	chr16	49637952	Silent	rs372206769	D400D	0.1
BLCA	chr16	49635994	Missense_Mutation	novel	S1053C	0.13
BLCA	chr16	49636714	Missense_Mutation	rs748113449	S813N	0.6
BLCA	chr16	49637556	Silent	novel	L532L	0.23
BLCA	chr16	49636096	Missense_Mutation	novel	G1019V	0.68
BLCA	chr16	49637290	Missense_Mutation	NA	S621L	0.41
BLCA	chr16	49637388	In_Frame_Del	novel	H588del	0.15
BRCA	chr16	49637521	Frame_Shift_Del	NA	*G544Afs5**	0.43
BRCA	chr16	49637851	Missense_Mutation	rs142517429	A434V	0.31
BRCA	chr16	49637372	Missense_Mutation	NA	A594S	0.58
BRCA	chr16	49626246	Silent	NA	T1167T	0.53
BRCA	chr16	49635842	Missense_Mutation	NA	V1104M	0.33
BRCA	chr16	49638855	Silent	rs376572236	Q99Q	0.45
BRCA	chr16	49626234	Missense_Mutation	novel	I1171M	0.03
BRCA	chr16	49635849	Silent	rs200411543	N1101N	0.4
BRCA	chr16	49638777	Silent	rs140519104	L125L	0.29
BRCA	chr16	49637780	Missense_Mutation	NA	E458K	0.33
BRCA	chr16	49490938	3'UTR	novel		0.18
BRCA	chr16	49637552	Missense_Mutation	rs749382074	E534K	0.37
BRCA	chr16	49637699	Missense_Mutation	novel	C485R	0.29
BRCA	chr16	49730821	Missense_Mutation	NA	F76C	0.67
CESC	chr16	49626210	Silent	rs76199401	N1179N	0.48
CESC	chr16	49637332	Missense_Mutation	rs754474774	S607L	0.45
CESC	chr16	49638257	Missense_Mutation	NA	H299D	0.51
CESC	chr16	49637903	Missense_Mutation	rs772823132	R417W	0.24
CESC	chr16	49637802	Missense_Mutation	NA	M450I	0.35
CESC	chr16	49679267	Intron	rs760413373		0.32
CESC	chr16	49636263	Missense_Mutation	NA	I963M	0.13
CESC	chr16	49679292	Intron	NA		0.46
CESC	chr16	49637775	Silent	rs370346450	H459H	0.37
CESC	chr16	49636506	Silent	rs369348426	S882S	0.26
CESC	chr16	49637282	Missense_Mutation	rs369619436	A624T	0.3
CESC	chr16	49637733	Silent	rs753825038	Q473Q	0.09
CESC	chr16	49637774	Missense_Mutation	NA	V460F	0.81
CHOL	chr16	49789519	Missense_Mutation	rs377503772	S15L	0.12
CHOL	chr16	49637724	Missense_Mutation	novel	N476K	0.11
COAD	chr16	49637886	Silent	novel	L422L	0.18
COAD	chr16	49635700	Missense_Mutation	NA	S1151N	0.32
COAD	chr16	49523634	Missense_Mutation	novel	T1272S	0.18
COAD	chr16	49637696	Missense_Mutation	novel	P486S	0.4
COAD	chr16	49626213	Missense_Mutation	novel	E1178D	0.19
COAD	chr16	49636900	Missense_Mutation	rs143285873	R751H	0.53
COAD	chr16	49636236	Silent	NA	L972L	0.18
COAD	chr16	49636368	Silent	NA	G928G	0.29
COAD	chr16	49638633	Silent	novel	R173R	0.09
COAD	chr16	49525375	Missense_Mutation	NA	V1233M	0.17
COAD	chr16	49637952	Silent	rs372206769	D400D	0.24
COAD	chr16	49636417	Missense_Mutation	rs767903828	R912Q	0.13
COAD	chr16	49638467	Missense_Mutation	NA	R229C	0.21
COAD	chr16	49637653	Missense_Mutation	rs779795080	R500H	0.1
COAD	chr16	49638027	Silent	rs375403632	S375S	0.34
COAD	chr16	49636901	Missense_Mutation	rs757246232	R751C	0.37
COAD	chr16	49636873	Missense_Mutation	rs368885869	R760H	0.23
COAD	chr16	49638062	Missense_Mutation	rs761674679	V364M	0.27
COAD	chr16	49637282	Missense_Mutation	rs369619436	A624T	0.36
COAD	chr16	49635797	Missense_Mutation	rs146352545	G1119S	0.25
COAD	chr16	49525442	Silent	rs376719006	P1210P	0.39
COAD	chr16	49636056	Silent	rs145829157	T1032T	0.25
COAD	chr16	49638814	Missense_Mutation	rs377052758	A113V	0.2
COAD	chr16	49638649	Missense_Mutation	NA	C168Y	0.4
COAD	chr16	49525394	Silent	rs766215720	G1226G	0.05
COAD	chr16	49635780	Silent	rs766652392	E1124E	0.32
COAD	chr16	49637973	Frame_Shift_Del	novel	*Q394Rfs36**	0.13
COAD	chr16	49636438	Missense_Mutation	rs777432098	R905Q	0.55
COAD	chr16	49635821	Missense_Mutation	NA	E1111K	0.59
COAD	chr16	49635790	Missense_Mutation	NA	R1121H	0.21
COAD	chr16	49637925	Silent	NA	Y409Y	0.18
COAD	chr16	49636098	Silent	novel	T1018T	0.34
COAD	chr16	49637044	Missense_Mutation	rs144284315	S703L	0.09
COAD	chr16	49636125	Missense_Mutation	novel	M1009I	0.32
COAD	chr16	49491193	3'UTR	novel		0.25
COAD	chr16	49637170	Missense_Mutation	rs145272522	K661T	0.08
COAD	chr16	49637959	Missense_Mutation	rs375001883	R398Q	0.33
COAD	chr16	49730906	Missense_Mutation	rs772307020	V48M	0.16
COAD	chr16	49638249	Silent	novel	P301P	0.18
COAD	chr16	49637120	Silent	NA	L678L	0.35
COAD	chr16	49636904	Missense_Mutation	novel	Y750H	0.06
COAD	chr16	49637445	Silent	NA	T569T	0.24
COAD	chr16	49637499	Silent	rs142344079	P551P	0.36
COAD	chr16	49525450	Missense_Mutation	novel	D1208N	0.63
COAD	chr16	49636180	Missense_Mutation	rs778205999	R991H	0.33
COAD	chr16	49636700	Missense_Mutation	novel	A818T	0.22
COAD	chr16	49638014	Missense_Mutation	NA	R380C	0.16
COAD	chr16	49637088	Silent	rs150555141	T688T	0.41
COAD	chr16	49637488	Missense_Mutation	NA	P555L	0.37
COAD	chr16	49637903	Missense_Mutation	rs772823132	R417W	0.36
COAD	chr16	49636758	Silent	NA	C798C	0.18
COAD	chr16	49636891	Missense_Mutation	NA	A754V	0.26
COAD	chr16	49730946	Silent	rs139517505	C34C	0.39
COAD	chr16	49637977	Missense_Mutation	NA	R392Q	0.53
COAD	chr16	49635996	Silent	rs117592972	A1052A	0.24
COAD	chr16	49730800	Missense_Mutation	rs200710667	T83M	0.49
COAD	chr16	49636252	Missense_Mutation	rs771703239	R967H	0.42
COAD	chr16	49637174	Missense_Mutation	rs779555962	R660W	0.17
COAD	chr16	49638236	Missense_Mutation	rs763435948	D306N	0.15
DLBC	chr16	49638533	Missense_Mutation	novel	D207N	0.33
ESCA	chr16	49822670	Missense_Mutation	rs776265059	V6I	0.62
ESCA	chr16	49635888	Silent	novel	P1088P	0.09
ESCA	chr16	49636000	Missense_Mutation	rs750497057	A1051V	0.25
ESCA	chr16	49490654	3'UTR	rs62029129		0.17
ESCA	chr16	49523692	Missense_Mutation	novel	G1253R	0.52
ESCA	chr16	49638198	Silent	rs377569533	H318H	0.59
ESCA	chr16	49636900	Missense_Mutation	rs143285873	R751H	0.5
ESCA	chr16	49636741	Missense_Mutation	novel	S804N	0.32
ESCA	chr16	49637806	Missense_Mutation	NA	S449F	0.46
ESCA	chr16	49635753	Missense_Mutation	novel	E1133D	0.32
GBM	chr16	49525442	Silent	rs376719006	P1210P	0.37
GBM	chr16	49638026	Missense_Mutation	rs562976839	A376T	0.48
GBM	chr16	49635752	Missense_Mutation	novel	D1134Y	0.43
GBM	chr16	49638510	Missense_Mutation	novel	K214N	0.24
GBM	chr16	49636711	Missense_Mutation	novel	K814M	0.16
GBM	chr16	49637258	Missense_Mutation	novel	Y632H	0.27
GBM	chr16	49638770	Missense_Mutation	rs781749862	G128S	0.26
GBM	chr16	49730913	Silent	novel	R45R	0.41
GBM	chr16	49638458	Missense_Mutation	novel	S232P	0.17
GBM	chr16	49637733	Missense_Mutation	novel	Q473H	0.16
HNSC	chr16	49636938	Silent	novel	H738H	0.31
HNSC	chr16	49637960	Silent	novel	R398R	0.09
HNSC	chr16	49525464	Missense_Mutation	novel	C1203Y	0.14
HNSC	chr16	49636480	Missense_Mutation	novel	C891Y	0.24
HNSC	chr16	49730883	Silent	novel	N55N	0.2
HNSC	chr16	49638852	Silent	novel	L100L	0.14
HNSC	chr16	49636786	Missense_Mutation	rs767082011	T789N	0.11
HNSC	chr16	49730805	Missense_Mutation	novel	D81E	0.05
HNSC	chr16	49638109	Missense_Mutation	novel	P348L	0.59
HNSC	chr16	49636965	Missense_Mutation	novel	F729L	0.09
HNSC	chr16	49637651	Missense_Mutation	rs750249389	V501I	0.08
HNSC	chr16	49636151	Missense_Mutation	novel	E1001K	0.14
HNSC	chr16	49637823	Nonsense_Mutation	novel	C443*	0.16
HNSC	chr16	49635724	Missense_Mutation	novel	H1143L	0.16
HNSC	chr16	49637602	Missense_Mutation	novel	F517S	0.64
HNSC	chr16	49730942	Missense_Mutation	rs756709776	Q36E	0.19
HNSC	chr16	49637719	Missense_Mutation	novel	S478C	0.22
HNSC	chr16	49730925	Silent	rs566780634	A41A	0.14
HNSC	chr16	49638467	Missense_Mutation	NA	R229C	0.1
HNSC	chr16	49635784	Missense_Mutation	novel	P1123L	0.27
HNSC	chr16	49638237	Silent	rs764527468	V305V	0.25
KICH	chr16	49637283	Silent	rs151294188	S623S	0.3
KIRC	chr16	49638644	Missense_Mutation	novel	Y170N	0.23
KIRC	chr16	49523698	Missense_Mutation	NA	V1251L	0.19
KIRC	chr16	49636933	Missense_Mutation	NA	A740V	0.16
KIRC	chr16	49636090	Missense_Mutation	NA	R1021H	0.34
KIRC	chr16	49636866	Silent	NA	E762E	0.27
KIRP	chr16	49636957	Missense_Mutation	NA	K732M	0.13
KIRP	chr16	49637367	Missense_Mutation	novel	H595Q	0.31
KIRP	chr16	49636274	Missense_Mutation	NA	M960V	0.19
KIRP	chr16	49730783	Missense_Mutation	rs146233664	R89C	0.29
KIRP	chr16	49636956	Missense_Mutation	NA	K732N	0.56
LAML	chr16	49637368	Missense_Mutation	novel	H595R	0.13
LAML	chr16	49638409	Missense_Mutation	novel	K248M	0.06
LAML	chr16	49822672	Missense_Mutation	novel	R5K	0.2
LGG	chr16	49491248	3'UTR	novel		0.26
LGG	chr16	49525393	Missense_Mutation	rs760436403	G1227S	0.31
LGG	chr16	49638577	Missense_Mutation	novel	K192R	0.12
LIHC	chr16	49637109	Silent	novel	L681L	0.32
LIHC	chr16	49626170	Nonsense_Mutation	novel	E1193*	0.69
LIHC	chr16	49525393	Missense_Mutation	rs760436403	G1227S	0.25
LIHC	chr16	49491262	3'UTR	novel		0.29
LIHC	chr16	49730931	Silent	NA	S39S	0.84
LIHC	chr16	49637388	Missense_Mutation	NA	H588Q	0.36
LIHC	chr16	49637627	Missense_Mutation	NA	N509H	0.38
LIHC	chr16	49637423	Missense_Mutation	novel	I577F	0.43
LIHC	chr16	49637079	Silent	novel	H691H	0.27
LUAD	chr16	49636320	Silent	NA	G944G	0.32
LUAD	chr16	49637851	Missense_Mutation	NA	A434E	0.42
LUAD	chr16	49636429	Frame_Shift_Ins	novel	*D908Gfs10**	0.3
LUAD	chr16	49638138	Silent	novel	V338V	0.22
LUAD	chr16	49636149	Missense_Mutation	NA	E1001D	0.2
LUAD	chr16	49638525	Silent	NA	L209L	0.21
LUAD	chr16	49491227	3'UTR	novel		0.18
LUAD	chr16	49636492	Missense_Mutation	NA	G887V	0.26
LUAD	chr16	49637237	Missense_Mutation	NA	L639F	0.11
LUAD	chr16	49637332	Nonsense_Mutation	NA	S607*	0.3
LUAD	chr16	49637810	Missense_Mutation	NA	D448Y	0.73
LUAD	chr16	49636509	Silent	novel	A881A	0.08
LUAD	chr16	49525432	Missense_Mutation	novel	L1214I	0.08
LUAD	chr16	49637603	Missense_Mutation	novel	F517V	0.11
LUAD	chr16	49637958	Silent	NA	R398R	0.11
LUAD	chr16	49638339	Silent	novel	T271T	0.18
LUAD	chr16	49637908	Missense_Mutation	NA	S415Y	0.35
LUAD	chr16	49638842	Missense_Mutation	NA	A104P	0.67
LUAD	chr16	49637421	Silent	novel	I577I	0.23
LUAD	chr16	49626201	Missense_Mutation	NA	E1182D	0.21
LUAD	chr16	49636833	Missense_Mutation	NA	H773Q	0.2
LUAD	chr16	49636293	Silent	novel	R953R	0.13
LUAD	chr16	49636294	Missense_Mutation	novel	R953L	0.14
LUAD	chr16	49636292	Missense_Mutation	NA	G954C	0.36
LUAD	chr16	49637977	Missense_Mutation	novel	R392L	0.11
LUAD	chr16	49491149	3'UTR	novel		0.1
LUAD	chr16	49638068	Missense_Mutation	novel	G362C	0.21
LUAD	chr16	49635859	Missense_Mutation	novel	R1098L	0.29
LUAD	chr16	49637630	Missense_Mutation	novel	A508S	0.17
LUAD	chr16	49491296	Silent	novel	T1278T	0.89
LUAD	chr16	49637288	Missense_Mutation	novel	A622S	0.2
LUAD	chr16	49635791	Missense_Mutation	novel	R1121S	0.3
LUAD	chr16	49638757	Missense_Mutation	NA	G132E	0.14
LUAD	chr16	49637040	Silent	novel	V704V	0.45
LUAD	chr16	49635716	Missense_Mutation	NA	L1146I	0.38
LUAD	chr16	49523738	Splice_Region	NA	V1237V	0.81
LUAD	chr16	49638219	Silent	NA	L311L	0.32
LUAD	chr16	49789499	Missense_Mutation	novel	V22L	0.35
LUAD	chr16	49636431	Silent	NA	R907R	0.13
LUAD	chr16	49635700	Missense_Mutation	novel	S1151I	0.53
LUAD	chr16	49491249	3'UTR	novel		0.16
LUAD	chr16	49637472	Missense_Mutation	NA	M560I	0.26
LUAD	chr16	49789541	Nonsense_Mutation	novel	E8*	0.5
LUAD	chr16	49525401	Missense_Mutation	rs753674596	G1224V	0.29
LUAD	chr16	49637469	Missense_Mutation	NA	E561D	0.24
LUAD	chr16	49822656	Splice_Site	novel	X6_splice	0.52
LUAD	chr16	49636670	Missense_Mutation	NA	E828K	0.12
LUAD	chr16	49636002	Silent	NA	S1050S	0.52
LUAD	chr16	49636234	Missense_Mutation	rs773947241	T973M	0.18
LUAD	chr16	49637908	Missense_Mutation	rs760242467	S415F	0.52
LUAD	chr16	49636152	Missense_Mutation	NA	E1000D	0.1
LUAD	chr16	49638756	Silent	NA	G132G	0.23
LUAD	chr16	49730927	Missense_Mutation	NA	A41S	0.11
LUAD	chr16	49636069	Missense_Mutation	NA	T1028K	0.21
LUAD	chr16	49636501	Missense_Mutation	NA	P884H	0.2
LUAD	chr16	49636343	Silent	NA	R937R	0.58
LUAD	chr16	49636077	Nonsense_Mutation	NA	C1025*	0.3
LUAD	chr16	49635759	Missense_Mutation	novel	S1131R	0.09
LUAD	chr16	49636478	Missense_Mutation	novel	G892R	0.15
LUAD	chr16	49637009	Missense_Mutation	novel	H715N	0.18
LUAD	chr16	49636795	Missense_Mutation	novel	C786F	0.85
LUAD	chr16	49638771	Silent	rs746399268	L127L	0.66
LUAD	chr16	49637383	Missense_Mutation	NA	N590S	0.21
LUAD	chr16	49525442	Silent	NA	P1210P	0.18
LUAD	chr16	49637151	Frame_Shift_Del	novel	C667*	0.12
LUSC	chr16	49636670	Missense_Mutation	NA	E828K	0.25
LUSC	chr16	49635839	Missense_Mutation	novel	G1105C	0.24
LUSC	chr16	49638736	Missense_Mutation	NA	P139H	0.16
LUSC	chr16	49636854	Missense_Mutation	NA	Q766H	0.46
LUSC	chr16	49638464	Missense_Mutation	NA	G230C	0.38
LUSC	chr16	49636253	Missense_Mutation	NA	R967S	0.56
LUSC	chr16	49789509	Missense_Mutation	novel	W18C	0.13
LUSC	chr16	49635963	Silent	novel	L1063L	0.11
LUSC	chr16	49636009	Missense_Mutation	novel	G1048V	0.17
LUSC	chr16	49635849	Silent	rs200411543	N1101N	0.18
LUSC	chr16	49638466	Missense_Mutation	NA	R229H	0.36
LUSC	chr16	49635853	Missense_Mutation	NA	A1100G	0.5
LUSC	chr16	49638292	Missense_Mutation	novel	P287Q	0.25
LUSC	chr16	49730840	Missense_Mutation	NA	D70Y	0.26
LUSC	chr16	49635870	Silent	novel	G1094G	0.73
LUSC	chr16	49638025	Missense_Mutation	novel	A376D	0.29
LUSC	chr16	49636681	Missense_Mutation	novel	K824M	0.4
LUSC	chr16	49638228	Missense_Mutation	novel	N308K	0.29
LUSC	chr16	49636725	Frame_Shift_Del	novel	C809*	0.17
LUSC	chr16	49637297	Silent	novel	R619R	0.28
LUSC	chr16	49636881	Missense_Mutation	NA	W757C	0.23
LUSC	chr16	49637215	Missense_Mutation	NA	S646I	0.38
LUSC	chr16	49637982	Silent	rs61747467	P390P	0.25
LUSC	chr16	49635942	Silent	NA	L1070L	0.18
LUSC	chr16	49638095	Missense_Mutation	novel	H353Y	0.11
LUSC	chr16	49638171	Missense_Mutation	novel	M327I	0.27
LUSC	chr16	49637244	Silent	rs765545274	Q636Q	0.33
LUSC	chr16	49638323	Missense_Mutation	NA	E277K	0.44
LUSC	chr16	49635847	Missense_Mutation	novel	G1102V	0.38
LUSC	chr16	49637134	Missense_Mutation	NA	S673F	0.14
LUSC	chr16	49636874	Missense_Mutation	rs764927116	R760C	0.2
LUSC	chr16	49636875	Silent	NA	F759F	0.21
LUSC	chr16	49635697	Missense_Mutation	novel	G1152E	0.18
LUSC	chr16	49638471	Nonsense_Mutation	novel	C227*	0.21
LUSC	chr16	49637717	In_Frame_Del	novel	V471_S478del	0.17
LUSC	chr16	49636865	Missense_Mutation	novel	A763P	0.32
LUSC	chr16	49638608	Missense_Mutation	novel	D182N	0.1
LUSC	chr16	49523642	Missense_Mutation	NA	F1269L	0.06
LUSC	chr16	49523726	Silent	NA	A1241A	0.18
LUSC	chr16	49638707	Missense_Mutation	novel	R149S	0.09
LUSC	chr16	49635972	Silent	novel	L1060L	0.63
LUSC	chr16	49637060	Missense_Mutation	rs148732968	D698N	0.41
LUSC	chr16	49730879	Missense_Mutation	novel	D57Y	0.18
LUSC	chr16	49638142	Missense_Mutation	NA	G337V	0.12
LUSC	chr16	49637759	Missense_Mutation	NA	K465E	0.37
LUSC	chr16	49635944	Missense_Mutation	novel	L1070F	0.24
LUSC	chr16	49636869	Missense_Mutation	NA	K761N	0.51
LUSC	chr16	49638091	Missense_Mutation	novel	S354I	0.23
LUSC	chr16	49638292	Missense_Mutation	novel	P287Q	0.16
LUSC	chr16	49523734	Missense_Mutation	novel	V1239F	0.85
LUSC	chr16	49635758	Missense_Mutation	novel	A1132T	0.19
LUSC	chr16	49730864	Missense_Mutation	novel	E62K	0.16
MESO	chr16	49638654	Missense_Mutation	novel	F166L	0.11
OV	chr16	49638671	Frame_Shift_Del	novel	*H156Qfs22**	0.24
OV	chr16	49730846	Missense_Mutation	novel	T68P	0.14
OV	chr16	49637109	Silent	novel	L681L	0.56
OV	chr16	49730859	Missense_Mutation	novel	D63E	0.07
OV	chr16	49789500	Silent	rs116537749	S21S	0.18
OV	chr16	49638624	Missense_Mutation	novel	K176N	0.23
OV	chr16	49730804	Silent	NA	L82L	0.27
OV	chr16	49638115	Missense_Mutation	rs753225898	R346Q	0.14
OV	chr16	49638533	Missense_Mutation	NA	D207Y	0.34
OV	chr16	49638643	Missense_Mutation	novel	Y170F	0.21
OV	chr16	49491238	3'UTR	novel		0.19
PAAD	chr16	49637173	Missense_Mutation	rs200218868	R660Q	0.18
PAAD	chr16	49491172	3'UTR	novel		0.09
PAAD	chr16	49635854	Missense_Mutation	rs778755872	A1100T	0.18
PAAD	chr16	49636180	Missense_Mutation	rs778205999	R991H	0.19
PAAD	chr16	49638198	Silent	rs377569533	H318H	0.27
PRAD	chr16	49636234	Missense_Mutation	rs773947241	T973M	0.1
PRAD	chr16	49635996	Silent	rs117592972	A1052A	0.18
READ	chr16	49491141	3'UTR	novel		0.43
READ	chr16	49730852	Missense_Mutation	novel	I66F	0.08
READ	chr16	49525432	Missense_Mutation	novel	L1214I	0.3
READ	chr16	49636550	Missense_Mutation	NA	A868T	0.43
READ	chr16	49637060	Missense_Mutation	rs148732968	D698N	0.44
READ	chr16	49637681	Missense_Mutation	rs138661785	D491N	0.32
READ	chr16	49638522	Missense_Mutation	rs751260245	K210N	0.41
READ	chr16	49637875	Missense_Mutation	novel	E426V	0.23
READ	chr16	49523632	Missense_Mutation	novel	E1273K	0.17
READ	chr16	49637282	Missense_Mutation	rs369619436	A624T	0.25
SARC	chr16	49636752	Missense_Mutation	novel	I800M	0.19
SARC	chr16	49636233	Silent	rs768277837	T973T	0.54
SKCM	chr16	49635791	Missense_Mutation	rs199542804	R1121C	0.24
SKCM	chr16	49637636	Missense_Mutation	NA	P506A	0.38
SKCM	chr16	49636692	Silent	NA	I820I	0.45
SKCM	chr16	49730971	Missense_Mutation	novel	G26E	0.31
SKCM	chr16	49637255	Missense_Mutation	NA	P633S	0.36
SKCM	chr16	49636671	Silent	novel	R827R	0.36
SKCM	chr16	49635755	Missense_Mutation	novel	E1133K	0.25
SKCM	chr16	49730840	Missense_Mutation	rs149531360	D70N	0.34
SKCM	chr16	49637574	Silent	NA	F526F	0.42
SKCM	chr16	49637478	Silent	novel	S558S	0.65
SKCM	chr16	49637479	Missense_Mutation	novel	S558F	0.64
SKCM	chr16	49635932	Missense_Mutation	rs373906393	R1074C	0.31
SKCM	chr16	49637329	Missense_Mutation	NA	S608Y	0.14
SKCM	chr16	49636059	Silent	NA	S1031S	0.31
SKCM	chr16	49638674	Missense_Mutation	NA	H160Y	0.46
SKCM	chr16	49523683	Missense_Mutation	novel	D1256N	0.56
SKCM	chr16	49523735	Silent	NA	F1238F	0.24
SKCM	chr16	49636620	Silent	NA	G844G	0.26
SKCM	chr16	49638054	Silent	NA	S366S	0.13
SKCM	chr16	49637574	Silent	NA	F526F	0.97
SKCM	chr16	49635863	Missense_Mutation	NA	A1097T	0.55
SKCM	chr16	49491198	3'UTR	novel		0.31
SKCM	chr16	49626209	Missense_Mutation	novel	E1180K	0.22
SKCM	chr16	49636882	Nonsense_Mutation	novel	W757*	0.14
SKCM	chr16	49637552	Missense_Mutation	rs749382074	E534K	0.37
SKCM	chr16	49730781	Silent	rs776280102	R89R	0.12
SKCM	chr16	49637574	Silent	NA	F526F	0.23
SKCM	chr16	49637498	Missense_Mutation	rs750884387	V552M	0.25
SKCM	chr16	49638193	Missense_Mutation	NA	N320S	0.39
SKCM	chr16	49637654	Missense_Mutation	rs376465155	R500C	0.42
SKCM	chr16	49636520	Missense_Mutation	NA	D878N	0.53
SKCM	chr16	49636964	Missense_Mutation	NA	D730N	0.46
SKCM	chr16	49638357	Silent	rs201499268	C265C	0.26
SKCM	chr16	49637951	Missense_Mutation	rs757406757	G401R	0.44
SKCM	chr16	49638668	Missense_Mutation	rs761575829	D162N	0.12
SKCM	chr16	49637478	Silent	novel	S558S	0.44
SKCM	chr16	49637479	Missense_Mutation	novel	S558F	0.43
SKCM	chr16	49730959	Missense_Mutation	NA	G30E	0.38
SKCM	chr16	49637047	Missense_Mutation	NA	S702F	0.15
SKCM	chr16	49638323	Missense_Mutation	NA	E277K	0.38
SKCM	chr16	49635673	Missense_Mutation	NA	S1160L	0.32
SKCM	chr16	49730820	Silent	rs138148545	F76F	0.42
SKCM	chr16	49730959	Missense_Mutation	NA	G30E	0.3
SKCM	chr16	49637310	Silent	novel	S614S	0.33
SKCM	chr16	49637311	Missense_Mutation	NA	S614F	0.34
SKCM	chr16	49638771	Silent	rs746399268	L127L	0.32
SKCM	chr16	49637292	Silent	rs747790367	L620L	0.15
SKCM	chr16	49637349	Silent	rs376118736	A601A	0.13
SKCM	chr16	49637350	Missense_Mutation	NA	A601V	0.12
SKCM	chr16	49636342	Missense_Mutation	NA	R937Q	0.26	zf-C2H2
SKCM	chr16	49637685	Silent	rs776964253	F489F	0.16
SKCM	chr16	49637919	Silent	rs776280246	C411C	0.49
SKCM	chr16	49636691	Silent	novel	L821L	0.56
SKCM	chr16	49636692	Silent	NA	I820I	0.56
SKCM	chr16	49637744	Missense_Mutation	NA	P470S	0.52
SKCM	chr16	49638000	Silent	rs748728165	P384P	0.37
SKCM	chr16	49638805	Missense_Mutation	rs376833288	T116M	0.35
SKCM	chr16	49636874	Missense_Mutation	rs764927116	R760C	0.32
SKCM	chr16	49637994	Silent	NA	S386S	0.18
SKCM	chr16	49635905	Missense_Mutation	NA	D1083H	0.53
SKCM	chr16	49638540	Silent	NA	S204S	0.25
SKCM	chr16	49636704	Silent	novel	F816F	0.5
SKCM	chr16	49491210	3'UTR	novel		0.1
SKCM	chr16	49637958	Silent	NA	R398R	0.24
SKCM	chr16	49636670	Missense_Mutation	NA	E828K	0.43
SKCM	chr16	49637544	Silent	rs780174138	I536I	0.46
SKCM	chr16	49636580	Silent	novel	L858L	0.44
SKCM	chr16	49636983	Silent	NA	T723T	0.43
SKCM	chr16	49637044	Missense_Mutation	rs144284315	S703L	0.28
SKCM	chr16	49730840	Missense_Mutation	rs149531360	D70N	0.63
SKCM	chr16	49730963	Missense_Mutation	novel	E29K	0.69
SKCM	chr16	49635702	Silent	NA	T1150T	0.41
SKCM	chr16	49636699	Missense_Mutation	NA	A818V	0.18
SKCM	chr16	49636929	Silent	NA	V741V	0.38
STAD	chr16	49636300	Missense_Mutation	rs200057861	T951M	0.28	zf-C2H2
STAD	chr16	49637813	Silent	novel	L447L	0.26
STAD	chr16	49491234	3'UTR	rs369770026		0.32
STAD	chr16	49637060	Missense_Mutation	rs148732968	D698N	0.18
STAD	chr16	49636056	Silent	rs145829157	T1032T	0.17
STAD	chr16	49638484	Missense_Mutation	novel	K223R	0.22
STAD	chr16	49730946	Silent	rs139517505	C34C	0.15
STAD	chr16	49638026	Frame_Shift_Del	novel	*A376Pfs13**	0.2
STAD	chr16	49638035	Missense_Mutation	NA	D373N	0.2
STAD	chr16	49638507	Silent	NA	T215T	0.11
STAD	chr16	49637500	Missense_Mutation	NA	P551Q	0.48
STAD	chr16	49637606	Missense_Mutation	NA	A516T	0.3
STAD	chr16	49636038	Silent	rs749408750	H1038H	0.26
STAD	chr16	49637339	Missense_Mutation	NA	P605T	0.25
STAD	chr16	49730925	Silent	rs566780634	A41A	0.26
STAD	chr16	49637661	Silent	NA	E497E	0.31
STAD	chr16	49638084	Missense_Mutation	NA	S356R	0.26
STAD	chr16	49730946	Silent	rs139517505	C34C	0.42
STAD	chr16	49636111	Missense_Mutation	rs762582497	R1014H	0.33
STAD	chr16	49636314	Silent	novel	R946R	0.42
STAD	chr16	49637386	Missense_Mutation	novel	K589R	0.48
STAD	chr16	49636512	Silent	rs376264701	D880D	0.11
STAD	chr16	49637174	Missense_Mutation	rs779555962	R660W	0.23
STAD	chr16	49636114	Missense_Mutation	NA	L1013P	0.15
STAD	chr16	49637086	Missense_Mutation	rs745433383	S689L	0.32
STAD	chr16	49637170	Missense_Mutation	rs145272522	K661T	0.23
STAD	chr16	49637800	Missense_Mutation	NA	P451H	0.06
STAD	chr16	49636898	Missense_Mutation	NA	C752R	0.25
STAD	chr16	49491145	3'UTR	novel		0.24
STAD	chr16	49637341	Missense_Mutation	novel	S604N	0.12
STAD	chr16	49637960	Missense_Mutation	rs368847069	R398W	0.23
STAD	chr16	49635849	Silent	rs200411543	N1101N	0.16
STAD	chr16	49636519	Missense_Mutation	NA	D878G	0.19
STAD	chr16	49637853	Silent	rs777932033	H433H	0.2
STAD	chr16	49638610	Missense_Mutation	rs778240903	R181H	0.22
STAD	chr16	49638795	Silent	rs371181840	I119I	0.29
STAD	chr16	49637044	Missense_Mutation	rs144284315	S703L	0.44
STAD	chr16	49637637	Silent	NA	G505G	0.28
STAD	chr16	49730819	Missense_Mutation	NA	E77K	0.26
STAD	chr16	49789530	Silent	NA	A11A	0.25
STAD	chr16	49491215	3'UTR	novel		0.29
STAD	chr16	49636242	Silent	NA	S970S	0.29
STAD	chr16	49636413	Silent	rs571689478	P913P	0.37
STAD	chr16	49635954	Silent	rs748651721	C1066C	0.45
STAD	chr16	49491259	3'UTR	novel		0.27
UCEC	chr16	49636555	Missense_Mutation	NA	P866H	0.36
UCEC	chr16	49636964	Missense_Mutation	NA	D730N	0.3
UCEC	chr16	49637588	Missense_Mutation	NA	C522R	0.32
UCEC	chr16	49730887	Missense_Mutation	NA	R54K	0.29
UCEC	chr16	49636775	Missense_Mutation	novel	E793K	0.35
UCEC	chr16	49637485	Missense_Mutation	rs573032120	T556M	0.18
UCEC	chr16	49637684	Missense_Mutation	rs771331763	A490T	0.15
UCEC	chr16	49638484	Missense_Mutation	novel	K223T	0.1
UCEC	chr16	49730971	Missense_Mutation	novel	G26E	0.19
UCEC	chr16	49730972	Splice_Site	novel	X26_splice	0.31
UCEC	chr16	49636232	Missense_Mutation	novel	L974F	0.39
UCEC	chr16	49637241	Silent	rs144950533	C637C	0.09
UCEC	chr16	49626228	Silent	rs373620289	C1173C	0.16
UCEC	chr16	49636965	Silent	rs138278000	F729F	0.62
UCEC	chr16	49525391	Silent	novel	G1227G	0.09
UCEC	chr16	49637780	Missense_Mutation	NA	E458K	0.41
UCEC	chr16	49730891	Missense_Mutation	novel	E53K	0.35
UCEC	chr16	49637853	Silent	rs777932033	H433H	0.26
UCEC	chr16	49638594	Missense_Mutation	novel	K186N	0.56
UCEC	chr16	49638240	Silent	NA	F304F	0.3
UCEC	chr16	49635697	Missense_Mutation	NA	G1152V	0.19
UCEC	chr16	49638246	Missense_Mutation	NA	E302D	0.26
UCEC	chr16	49638743	Missense_Mutation	NA	P137S	0.36
UCEC	chr16	49822737	5'UTR	novel		0.11
UCEC	chr16	49789489	Missense_Mutation	novel	A25V	0.15
UCEC	chr16	49638049	Missense_Mutation	novel	S368N	0.18
UCEC	chr16	49638177	Silent	novel	C325C	0.38
UCEC	chr16	49637838	Silent	novel	Q438Q	0.09
UCEC	chr16	49525450	Missense_Mutation	novel	D1208N	0.22
UCEC	chr16	49490993	3'UTR	novel		0.7
UCEC	chr16	49626209	Missense_Mutation	novel	E1180K	0.47
UCEC	chr16	49636049	Missense_Mutation	novel	L1035F	0.29
UCEC	chr16	49637338	Missense_Mutation	novel	P605L	0.06
UCEC	chr16	49491149	3'UTR	novel		0.31
UCEC	chr16	49636439	Missense_Mutation	novel	R905W	0.4
UCEC	chr16	49638350	Missense_Mutation	novel	C268R	0.42
UCEC	chr16	49636315	Missense_Mutation	rs757677116	R946Q	0.44	zf-C2H2
UCEC	chr16	49636457	Missense_Mutation	novel	V899M	0.53
UCEC	chr16	49636965	Silent	rs138278000	F729F	0.15
UCEC	chr16	49638328	Missense_Mutation	rs553506281	T275M	0.1
UCEC	chr16	49490663	3'UTR	novel		0.58
UCEC	chr16	49491120	3'UTR	novel		0.19
UCEC	chr16	49636507	Missense_Mutation	rs777639594	S882L	0.56
UCEC	chr16	49637770	Missense_Mutation	rs200959271	R461H	0.5
UCEC	chr16	49638022	Missense_Mutation	novel	S377Y	0.55
UCEC	chr16	49638240	Silent	NA	F304F	0.37
UCEC	chr16	49638770	Missense_Mutation	rs781749862	G128S	0.5
UCEC	chr16	49491236	3'UTR	novel		0.55
UCEC	chr16	49638684	Silent	rs550048605	H156H	0.13
UCEC	chr16	49490777	3'UTR	novel		0.29
UCEC	chr16	49490938	3'UTR	novel		0.44
UCEC	chr16	49636488	Silent	novel	C888C	0.2
UCEC	chr16	49636861	Missense_Mutation	novel	D764G	0.41
UCEC	chr16	49638677	Missense_Mutation	novel	I159F	0.43
UCEC	chr16	49637880	Silent	NA	V424V	0.27
UCEC	chr16	49635816	Silent	rs372366526	P1112P	0.33
UCEC	chr16	49638133	Missense_Mutation	NA	C340F	0.26
UCEC	chr16	49525420	Missense_Mutation	NA	I1218V	0.33
UCEC	chr16	49637485	Missense_Mutation	rs573032120	T556M	0.11
UCEC	chr16	49638347	Missense_Mutation	rs745876102	E269K	0.17
UCEC	chr16	49636000	Missense_Mutation	rs750497057	A1051V	0.49
UCEC	chr16	49637684	Missense_Mutation	rs771331763	A490T	0.31
UCEC	chr16	49491099	3'UTR	novel		0.3
UCEC	chr16	49638240	Silent	NA	F304F	0.33
UCEC	chr16	49730782	Missense_Mutation	rs745597535	R89H	0.49
UCEC	chr16	49636180	Missense_Mutation	rs778205999	R991H	0.38
UCEC	chr16	49637282	Missense_Mutation	rs369619436	A624T	0.38
UCEC	chr16	49638240	Silent	NA	F304F	0.49
UCEC	chr16	49638581	Missense_Mutation	NA	D191N	0.43
UCEC	chr16	49637339	Missense_Mutation	NA	P605T	0.39
UCEC	chr16	49636253	Missense_Mutation	rs773112623	R967C	0.24
UCEC	chr16	49637651	Missense_Mutation	rs750249389	V501I	0.44
UCEC	chr16	49525406	Silent	rs371710780	F1222F	0.07
UCEC	chr16	49626216	Silent	rs370042590	F1177F	0.2
UCEC	chr16	49637626	Missense_Mutation	novel	N509S	0.18
UCEC	chr16	49525373	Silent	novel	V1233V	0.48
UCEC	chr16	49638814	Missense_Mutation	NA	A113E	0.04
UCEC	chr16	49637296	Missense_Mutation	rs201174934	R619Q	0.27
UCEC	chr16	49638357	Silent	rs201499268	C265C	0.43
UCEC	chr16	49636672	Missense_Mutation	NA	R827Q	0.48
UCEC	chr16	49638466	Missense_Mutation	NA	R229H	0.52
UCEC	chr16	49636512	Silent	rs376264701	D880D	0.27
UCEC	chr16	49636433	Missense_Mutation	rs544721667	R907W	0.38
UCEC	chr16	49637552	Missense_Mutation	rs749382074	E534K	0.39
UCEC	chr16	49525453	Missense_Mutation	novel	F1207L	0.2
UCEC	chr16	49636893	Silent	rs758301410	T753T	0.35
UCEC	chr16	49637622	Silent	novel	P510P	0.2
UCEC	chr16	49637885	Missense_Mutation	novel	A423T	0.32
UCEC	chr16	49637771	Missense_Mutation	rs569507095	R461C	0.4
UCEC	chr16	49638026	Missense_Mutation	rs562976839	A376T	0.3
UCEC	chr16	49638791	Missense_Mutation	NA	D121Y	0.27
UCEC	chr16	49491140	3'UTR	novel		0.4
UCEC	chr16	49523696	Silent	novel	V1251V	0.27
UCEC	chr16	49635902	Missense_Mutation	rs759221881	V1084I	0.37
UCEC	chr16	49636226	Missense_Mutation	novel	E976K	0.44
UCEC	chr16	49637108	Missense_Mutation	novel	T682S	0.4
UCEC	chr16	49637629	Missense_Mutation	NA	A508V	0.26
UCEC	chr16	49638000	Silent	rs748728165	P384P	0.37
UCEC	chr16	49730799	Silent	rs762110313	T83T	0.36
UVM	chr16	49635691	Missense_Mutation	rs532940886	R1154Q	0.31
UVM	chr16	49638347	Missense_Mutation	rs745876102	E269K	0.29

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
CESC	DEL	0.1458	0.017271
CHOL	DEL	0.1944	0.23475
SARC	DEL	0.4825	0.0011106
SKCM	DEL	0.2779	0.036923
TGCT	AMP	0.0867	0.035574
UCEC	DEL	0.2208	4.7164e-05

Survival Analysis

Cancer	P-value	Q-value
KIRC	0.0074	Kaplan-Meier Survival Analysis
STAD	0.007	Kaplan-Meier Survival Analysis
ACC	0.0018	Kaplan-Meier Survival Analysis
SKCM	0.036	Kaplan-Meier Survival Analysis
LUSC	0.016	Kaplan-Meier Survival Analysis
LAML	0.003	Kaplan-Meier Survival Analysis
KICH	0.011	Kaplan-Meier Survival Analysis
LIHC	0.04	Kaplan-Meier Survival Analysis
LGG	0.00046	Kaplan-Meier Survival Analysis
THCA	0.045	Kaplan-Meier Survival Analysis
UVM	0.0028	Kaplan-Meier Survival Analysis

Drugs

EuRBPDB

Description

RBDs

Expression

Transcripts

Gene Model

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

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Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742