EuRBPDB

Description

Ensembl ID: ENSG00000103512 (Gene tree)
Gene ID: 23420
Gene Symbol: NOMO1
Alias: PM5
Full Name: NODAL modulator 1
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Plus strand
Length: 62,480 bases
Position: chr16:14,833,681-14,896,160
Accession: 30060
RBP type: non-canonical RBP
Summary: This gene encodes a protein originally thought to be related to the collagenase gene family. This gene is one of three highly similar genes in a region of duplication located on the p arm of chromosome 16. These three genes encode closely related proteins that may have the same function. The protein encoded by one of these genes has been identified as part of a protein complex that participates in the Nodal signaling pathway during vertebrate development. Mutations in ABCC6, which is located nearby, rather than mutations in this gene are associated with pseudoxanthoma elasticum (PXE). [provided by RefSeq, Jul 2008]

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000610363	NOMO1-207	3765	-	ENSP00000479933	1100 (aa)	-	A0A087WW46
ENST00000287667	NOMO1-201	4355	-	ENSP00000287667	1222 (aa)	-	Q15155
ENST00000566823	NOMO1-204	1898	-	-	- (aa)	-	-
ENST00000566720	NOMO1-203	548	-	-	- (aa)	-	-
ENST00000565655	NOMO1-202	666	-	ENSP00000457581	144 (aa)	-	H3BUC9
ENST00000566883	NOMO1-205	560	-	-	- (aa)	-	-
ENST00000566917	NOMO1-206	592	-	-	- (aa)	-	-
ENST00000620755	NOMO1-208	3921	-	ENSP00000483827	1267 (aa)	-	A0A087X117

Gene Model

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000103512	rs4780563	16	14881435	A	Educational attainment (MTAG)	30038396	[0.0087-0.0157] unit decrease	0.0122	EFO_0004784
ENSG00000103512	rs4780563	16	14881435	?	Educational attainment (years of education)	30595370			EFO_0004784

Protein-Protein Interaction (PPI)

* RBP PPI network refers to all genes directly bind to RBP

Orthologs identified by RBPome

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000103512	NOMO1	99	93.706	ENSMUSG00000030835	Nomo1	99	93.449	Mus_musculus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0003674	molecular_function	-	ND	Function
GO:0005575	cellular_component	-	ND	Component
GO:0005789	endoplasmic reticulum membrane	21873635.	IBA	Component
GO:0008150	biological_process	-	ND	Process
GO:0016020	membrane	19946888.	HDA	Component
GO:0016021	integral component of membrane	-	IEA	Component
GO:0030246	carbohydrate binding	-	IEA	Function