EuRBPDB

Description

RBDs

Expression

Transcripts

Gene Model

GWAS

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000104299 (Gene tree)
Gene ID: 55756
Gene Symbol: INTS9
Alias: FLJ10871|CPSF2L|RC-74
Full Name: integrator complex subunit 9
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Minus strand
Length: 122,732 bases
Position: chr8:28,767,658-28,890,389
Accession: 25592
RBP type: canonical RBP
Summary: This gene encodes a subunit of the Integrator complex. This protein complex binds the C-terminal domain of RNA polymerase II and likely plays a role in small nuclear RNA processing. The encoded protein has similarities to the subunits of the cleavage and polyadenylation specificity factor complex. Alternatively spliced transcript variants have been described.[provided by RefSeq, Feb 2010]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000430943	Beta-Casp	PF10996.8	2.2e-06	1	1
ENSP00000398208	Beta-Casp	PF10996.8	2.2e-06	1	1
ENSP00000429065	Beta-Casp	PF10996.8	2.3e-06	1	1

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000521070	INTS9-212	682	-	-	- (aa)	-	-
ENST00000524081	INTS9-219	668	-	ENSP00000429539	223 (aa)	-	H0YBH8
ENST00000517383	INTS9-202	686	-	ENSP00000429691	150 (aa)	-	H0YBK3
ENST00000523436	INTS9-218	929	-	ENSP00000427789	300 (aa)	-	E5RG70
ENST00000523303	INTS9-217	2578	-	ENSP00000427952	525 (aa)	-	G3XAN1
ENST00000520437	INTS9-208	416	-	ENSP00000430067	25 (aa)	-	H0YBQ3
ENST00000519578	INTS9-204	578	-	-	- (aa)	-	-
ENST00000520005	INTS9-205	588	-	-	- (aa)	-	-
ENST00000523076	INTS9-216	314	-	-	- (aa)	-	-
ENST00000521022	INTS9-211	2544	XM_006716356	ENSP00000429065	658 (aa)	XP_006716420	Q9NV88
ENST00000522363	INTS9-215	2045	-	ENSP00000430083	38 (aa)	-	E5RGY2
ENST00000520831	INTS9-209	498	-	-	- (aa)	-	-
ENST00000522074	INTS9-214	718	-	-	- (aa)	-	-
ENST00000521777	INTS9-213	2430	XM_011544574	ENSP00000430943	634 (aa)	XP_011542876	Q9NV88
ENST00000416984	INTS9-201	2759	XM_011544573	ENSP00000398208	637 (aa)	XP_011542875	Q9NV88
ENST00000520316	INTS9-207	692	-	-	- (aa)	-	-
ENST00000518510	INTS9-203	756	-	ENSP00000428135	170 (aa)	-	E5RK47
ENST00000520983	INTS9-210	1154	-	-	- (aa)	-	-
ENST00000520184	INTS9-206	559	-	ENSP00000429188	87 (aa)	-	E5RJ88

Gene Model

Click here to download ENSG00000104299's gene model file

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000104299	rs34807077	8	28823252	A	Educational attainment (MTAG)	30038396	[0.0077-0.0147] unit increase	0.0112	EFO_0004784
ENSG00000104299	rs34807077	8	28823252	A	Educational attainment (years of education)	30038396	[0.0091-0.0165] unit increase	0.0128	EFO_0004784
ENSG00000104299	rs35927132	8	28825783	T	Educational attainment (years of education)	30038396	[0.009-0.0164] unit increase	0.0127	EFO_0004784
ENSG00000104299	rs241178	8	28768901	?	High density lipoprotein cholesterol levels	30498476			EFO_0004612

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000104299's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000104299	INTS9	99	86.042	ENSAPOG00000023931	ints9	100	81.319	Acanthochromis_polyacanthus
ENSG00000104299	INTS9	100	100.000	ENSAMEG00000015995	INTS9	99	98.015	Ailuropoda_melanoleuca
ENSG00000104299	INTS9	99	82.027	ENSACIG00000012679	ints9	100	80.063	Amphilophus_citrinellus
ENSG00000104299	INTS9	99	86.042	ENSAOCG00000013267	ints9	100	81.319	Amphiprion_ocellaris
ENSG00000104299	INTS9	99	85.660	ENSAPEG00000015363	ints9	100	81.005	Amphiprion_percula
ENSG00000104299	INTS9	99	86.233	ENSATEG00000016623	ints9	100	81.790	Anabas_testudineus
ENSG00000104299	INTS9	100	94.253	ENSAPLG00000006167	INTS9	100	93.435	Anas_platyrhynchos
ENSG00000104299	INTS9	99	93.499	ENSACAG00000010181	INTS9	100	90.729	Anolis_carolinensis
ENSG00000104299	INTS9	100	100.000	ENSANAG00000031763	INTS9	100	93.921	Aotus_nancymaae
ENSG00000104299	INTS9	99	82.792	ENSACLG00000007637	ints9	100	80.691	Astatotilapia_calliptera
ENSG00000104299	INTS9	99	85.851	ENSAMXG00000018614	ints9	99	82.667	Astyanax_mexicanus
ENSG00000104299	INTS9	100	100.000	ENSBTAG00000008845	INTS9	100	97.872	Bos_taurus
ENSG00000104299	INTS9	100	35.632	WBGene00017608	F19F10.12	75	34.677	Caenorhabditis_elegans
ENSG00000104299	INTS9	100	99.686	ENSCJAG00000015614	INTS9	100	99.686	Callithrix_jacchus
ENSG00000104299	INTS9	100	100.000	ENSCAFG00000008263	INTS9	100	97.872	Canis_familiaris
ENSG00000104299	INTS9	100	100.000	ENSCAFG00020012346	INTS9	100	97.872	Canis_lupus_dingo
ENSG00000104299	INTS9	100	100.000	ENSCHIG00000012847	INTS9	100	97.872	Capra_hircus
ENSG00000104299	INTS9	100	98.784	ENSTSYG00000011662	INTS9	100	98.784	Carlito_syrichta
ENSG00000104299	INTS9	97	89.694	ENSCAPG00000012568	INTS9	96	89.694	Cavia_aperea
ENSG00000104299	INTS9	100	98.851	ENSCPOG00000013825	INTS9	100	98.632	Cavia_porcellus
ENSG00000104299	INTS9	100	100.000	ENSCCAG00000005937	INTS9	100	100.000	Cebus_capucinus
ENSG00000104299	INTS9	100	98.851	ENSCATG00000042463	INTS9	100	94.769	Cercocebus_atys
ENSG00000104299	INTS9	100	98.896	ENSCLAG00000015789	INTS9	100	98.784	Chinchilla_lanigera
ENSG00000104299	INTS9	100	99.848	ENSCSAG00000015899	INTS9	100	99.848	Chlorocebus_sabaeus
ENSG00000104299	INTS9	100	93.103	ENSCHOG00000011676	INTS9	87	98.387	Choloepus_hoffmanni
ENSG00000104299	INTS9	100	95.402	ENSCPBG00000019907	INTS9	100	94.833	Chrysemys_picta_bellii
ENSG00000104299	INTS9	100	60.674	ENSCSAVG00000003803	-	99	49.924	Ciona_savignyi
ENSG00000104299	INTS9	100	100.000	ENSCANG00000038080	INTS9	100	95.441	Colobus_angolensis_palliatus
ENSG00000104299	INTS9	100	100.000	ENSCGRG00001024549	Ints9	99	98.328	Cricetulus_griseus_chok1gshd
ENSG00000104299	INTS9	100	100.000	ENSCGRG00000014306	Ints9	96	98.321	Cricetulus_griseus_crigri
ENSG00000104299	INTS9	99	85.277	ENSCSEG00000019034	ints9	100	80.547	Cynoglossus_semilaevis
ENSG00000104299	INTS9	99	86.807	ENSCVAG00000001559	ints9	100	81.763	Cyprinodon_variegatus
ENSG00000104299	INTS9	99	85.660	ENSDARG00000067913	ints9	100	80.243	Danio_rerio
ENSG00000104299	INTS9	100	97.701	ENSDNOG00000003821	INTS9	100	93.617	Dasypus_novemcinctus
ENSG00000104299	INTS9	100	98.851	ENSDORG00000008604	Ints9	99	98.015	Dipodomys_ordii
ENSG00000104299	INTS9	100	59.091	FBgn0036570	IntS9	100	52.030	Drosophila_melanogaster
ENSG00000104299	INTS9	99	81.208	ENSETEG00000004286	INTS9	83	92.262	Echinops_telfairi
ENSG00000104299	INTS9	99	73.040	ENSEBUG00000010143	ints9	100	67.982	Eptatretus_burgeri
ENSG00000104299	INTS9	100	100.000	ENSEASG00005016353	INTS9	100	98.024	Equus_asinus_asinus
ENSG00000104299	INTS9	100	100.000	ENSECAG00000019848	INTS9	100	98.024	Equus_caballus
ENSG00000104299	INTS9	99	86.042	ENSELUG00000010313	ints9	100	81.307	Esox_lucius
ENSG00000104299	INTS9	100	100.000	ENSFCAG00000003520	INTS9	100	98.176	Felis_catus
ENSG00000104299	INTS9	100	94.253	ENSFALG00000010840	INTS9	100	93.617	Ficedula_albicollis
ENSG00000104299	INTS9	100	97.950	ENSFDAG00000021050	INTS9	100	97.872	Fukomys_damarensis
ENSG00000104299	INTS9	99	86.042	ENSFHEG00000022949	ints9	100	81.003	Fundulus_heteroclitus
ENSG00000104299	INTS9	99	84.808	ENSGMOG00000005180	ints9	100	79.084	Gadus_morhua
ENSG00000104299	INTS9	100	93.161	ENSGALG00000016631	INTS9	100	93.161	Gallus_gallus
ENSG00000104299	INTS9	99	86.424	ENSGAFG00000009314	ints9	100	81.155	Gambusia_affinis
ENSG00000104299	INTS9	99	85.468	ENSGACG00000004893	ints9	100	80.699	Gasterosteus_aculeatus
ENSG00000104299	INTS9	100	94.253	ENSGAGG00000015959	INTS9	100	94.006	Gopherus_agassizii
ENSG00000104299	INTS9	100	100.000	ENSGGOG00000017009	INTS9	100	100.000	Gorilla_gorilla
ENSG00000104299	INTS9	99	85.851	ENSHBUG00000000821	ints9	100	80.547	Haplochromis_burtoni
ENSG00000104299	INTS9	100	98.423	ENSHGLG00000005379	INTS9	100	98.321	Heterocephalus_glaber_female
ENSG00000104299	INTS9	100	98.580	ENSHGLG00100010972	INTS9	100	98.473	Heterocephalus_glaber_male
ENSG00000104299	INTS9	99	85.851	ENSHCOG00000019893	ints9	100	80.909	Hippocampus_comes
ENSG00000104299	INTS9	99	84.704	ENSIPUG00000020540	ints9	100	79.787	Ictalurus_punctatus
ENSG00000104299	INTS9	100	100.000	ENSSTOG00000011703	INTS9	100	98.331	Ictidomys_tridecemlineatus
ENSG00000104299	INTS9	99	86.233	ENSKMAG00000003883	ints9	95	86.207	Kryptolebias_marmoratus
ENSG00000104299	INTS9	99	86.807	ENSLBEG00000023003	ints9	100	82.067	Labrus_bergylta
ENSG00000104299	INTS9	83	85.388	ENSLACG00000005787	INTS9	100	83.883	Latimeria_chalumnae
ENSG00000104299	INTS9	99	88.337	ENSLOCG00000015999	ints9	100	83.891	Lepisosteus_oculatus
ENSG00000104299	INTS9	100	97.161	ENSLAFG00000014628	INTS9	99	97.099	Loxodonta_africana
ENSG00000104299	INTS9	100	99.843	ENSMFAG00000043511	INTS9	100	99.843	Macaca_fascicularis
ENSG00000104299	INTS9	100	99.848	ENSMMUG00000019723	INTS9	100	99.848	Macaca_mulatta
ENSG00000104299	INTS9	100	99.848	ENSMNEG00000035204	INTS9	100	100.000	Macaca_nemestrina
ENSG00000104299	INTS9	100	99.848	ENSMLEG00000027845	INTS9	100	99.848	Mandrillus_leucophaeus
ENSG00000104299	INTS9	99	86.998	ENSMAMG00000007772	ints9	100	81.915	Mastacembelus_armatus
ENSG00000104299	INTS9	99	86.042	ENSMZEG00005003651	ints9	100	80.699	Maylandia_zebra
ENSG00000104299	INTS9	100	93.103	ENSMGAG00000014182	INTS9	100	93.130	Meleagris_gallopavo
ENSG00000104299	INTS9	100	100.000	ENSMAUG00000016286	Ints9	100	98.168	Mesocricetus_auratus
ENSG00000104299	INTS9	100	95.741	ENSMICG00000010411	INTS9	100	98.765	Microcebus_murinus
ENSG00000104299	INTS9	100	98.587	ENSMOCG00000009792	Ints9	99	96.313	Microtus_ochrogaster
ENSG00000104299	INTS9	99	82.792	ENSMMOG00000015648	ints9	100	81.476	Mola_mola
ENSG00000104299	INTS9	100	97.701	ENSMODG00000008755	INTS9	99	96.285	Monodelphis_domestica
ENSG00000104299	INTS9	99	86.233	ENSMALG00000019769	ints9	100	81.763	Monopterus_albus
ENSG00000104299	INTS9	100	100.000	MGP_CAROLIEiJ_G0019419	-	96	97.568	Mus_caroli
ENSG00000104299	INTS9	100	100.000	ENSMUSG00000021975	Ints9	96	97.264	Mus_musculus
ENSG00000104299	INTS9	100	100.000	MGP_PahariEiJ_G0030437	-	96	97.720	Mus_pahari
ENSG00000104299	INTS9	100	100.000	MGP_SPRETEiJ_G0020311	-	96	97.416	Mus_spretus
ENSG00000104299	INTS9	99	92.222	ENSMPUG00000000997	INTS9	99	90.076	Mustela_putorius_furo
ENSG00000104299	INTS9	100	98.851	ENSMLUG00000012438	INTS9	99	97.869	Myotis_lucifugus
ENSG00000104299	INTS9	100	97.720	ENSNGAG00000024198	Ints9	99	97.720	Nannospalax_galili
ENSG00000104299	INTS9	100	77.429	ENSNBRG00000018303	ints9	100	77.429	Neolamprologus_brichardi
ENSG00000104299	INTS9	100	99.544	ENSNLEG00000016658	INTS9	100	99.544	Nomascus_leucogenys
ENSG00000104299	INTS9	100	98.851	ENSOPRG00000013568	INTS9	100	89.783	Ochotona_princeps
ENSG00000104299	INTS9	100	95.462	ENSODEG00000007631	INTS9	100	95.462	Octodon_degus
ENSG00000104299	INTS9	99	86.042	ENSONIG00000001202	ints9	100	80.699	Oreochromis_niloticus
ENSG00000104299	INTS9	99	85.333	ENSOANG00000010536	INTS9	98	85.781	Ornithorhynchus_anatinus
ENSG00000104299	INTS9	100	98.936	ENSOCUG00000015356	INTS9	100	98.936	Oryctolagus_cuniculus
ENSG00000104299	INTS9	99	86.042	ENSORLG00000015930	ints9	100	81.003	Oryzias_latipes
ENSG00000104299	INTS9	99	86.233	ENSORLG00020006084	ints9	100	81.155	Oryzias_latipes_hni
ENSG00000104299	INTS9	99	86.233	ENSORLG00015001448	ints9	100	81.155	Oryzias_latipes_hsok
ENSG00000104299	INTS9	99	86.233	ENSOMEG00000014390	ints9	100	81.790	Oryzias_melastigma
ENSG00000104299	INTS9	100	98.851	ENSOGAG00000015946	INTS9	100	97.264	Otolemur_garnettii
ENSG00000104299	INTS9	100	100.000	ENSOARG00000015017	INTS9	100	98.024	Ovis_aries
ENSG00000104299	INTS9	100	100.000	ENSPPAG00000041473	INTS9	100	99.848	Pan_paniscus
ENSG00000104299	INTS9	100	100.000	ENSPPRG00000005064	INTS9	100	98.024	Panthera_pardus
ENSG00000104299	INTS9	100	100.000	ENSPTIG00000018770	INTS9	100	98.024	Panthera_tigris_altaica
ENSG00000104299	INTS9	100	92.308	ENSPTRG00000020125	INTS9	100	92.553	Pan_troglodytes
ENSG00000104299	INTS9	100	99.696	ENSPANG00000016305	INTS9	100	99.696	Papio_anubis
ENSG00000104299	INTS9	99	86.042	ENSPKIG00000021742	ints9	100	81.307	Paramormyrops_kingsleyae
ENSG00000104299	INTS9	100	94.253	ENSPSIG00000017113	INTS9	100	93.849	Pelodiscus_sinensis
ENSG00000104299	INTS9	99	83.365	ENSPMGG00000016805	ints9	100	80.848	Periophthalmus_magnuspinnatus
ENSG00000104299	INTS9	100	100.000	ENSPEMG00000023972	Ints9	96	98.176	Peromyscus_maniculatus_bairdii
ENSG00000104299	INTS9	99	46.309	ENSPMAG00000005987	ints9	100	71.429	Petromyzon_marinus
ENSG00000104299	INTS9	100	97.701	ENSPCIG00000029178	INTS9	100	96.201	Phascolarctos_cinereus
ENSG00000104299	INTS9	99	86.286	ENSPFOG00000012194	ints9	100	81.061	Poecilia_formosa
ENSG00000104299	INTS9	99	86.998	ENSPLAG00000020521	ints9	100	81.611	Poecilia_latipinna
ENSG00000104299	INTS9	99	86.424	ENSPMEG00000004545	ints9	100	81.155	Poecilia_mexicana
ENSG00000104299	INTS9	99	86.424	ENSPREG00000018730	ints9	100	81.155	Poecilia_reticulata
ENSG00000104299	INTS9	100	99.848	ENSPPYG00000018479	INTS9	100	99.848	Pongo_abelii
ENSG00000104299	INTS9	100	97.701	ENSPCOG00000026338	INTS9	100	95.725	Propithecus_coquereli
ENSG00000104299	INTS9	100	98.851	ENSPVAG00000007821	INTS9	100	97.405	Pteropus_vampyrus
ENSG00000104299	INTS9	99	82.792	ENSPNYG00000021900	ints9	100	80.691	Pundamilia_nyererei
ENSG00000104299	INTS9	99	86.424	ENSPNAG00000011555	ints9	100	81.307	Pygocentrus_nattereri
ENSG00000104299	INTS9	100	100.000	ENSRNOG00000013459	LOC102549712	100	97.416	Rattus_norvegicus
ENSG00000104299	INTS9	100	100.000	ENSRBIG00000038084	INTS9	100	100.000	Rhinopithecus_bieti
ENSG00000104299	INTS9	100	100.000	ENSRROG00000040531	INTS9	100	100.000	Rhinopithecus_roxellana
ENSG00000104299	INTS9	100	100.000	ENSSBOG00000034897	INTS9	100	99.848	Saimiri_boliviensis_boliviensis
ENSG00000104299	INTS9	99	87.380	ENSSFOG00015001945	ints9	100	82.889	Scleropages_formosus
ENSG00000104299	INTS9	99	86.233	ENSSMAG00000004512	ints9	100	81.611	Scophthalmus_maximus
ENSG00000104299	INTS9	99	85.851	ENSSDUG00000006662	ints9	100	81.003	Seriola_dumerili
ENSG00000104299	INTS9	99	85.851	ENSSLDG00000004386	ints9	100	81.003	Seriola_lalandi_dorsalis
ENSG00000104299	INTS9	57	95.294	ENSSARG00000000645	-	80	90.244	Sorex_araneus
ENSG00000104299	INTS9	100	94.253	ENSSPUG00000003374	INTS9	100	85.106	Sphenodon_punctatus
ENSG00000104299	INTS9	99	86.042	ENSSPAG00000013106	ints9	100	81.459	Stegastes_partitus
ENSG00000104299	INTS9	100	100.000	ENSSSCG00000009681	INTS9	100	98.176	Sus_scrofa
ENSG00000104299	INTS9	100	94.253	ENSTGUG00000013325	INTS9	99	93.130	Taeniopygia_guttata
ENSG00000104299	INTS9	99	86.424	ENSTRUG00000006014	ints9	100	80.699	Takifugu_rubripes
ENSG00000104299	INTS9	99	85.551	ENSTNIG00000009717	ints9	100	80.484	Tetraodon_nigroviridis
ENSG00000104299	INTS9	100	100.000	ENSTBEG00000016188	INTS9	91	91.833	Tupaia_belangeri
ENSG00000104299	INTS9	100	94.377	ENSTTRG00000009079	INTS9	100	94.377	Tursiops_truncatus
ENSG00000104299	INTS9	100	100.000	ENSUMAG00000022190	INTS9	99	94.656	Ursus_maritimus
ENSG00000104299	INTS9	100	100.000	ENSVVUG00000003168	INTS9	100	98.024	Vulpes_vulpes
ENSG00000104299	INTS9	99	86.616	ENSXMAG00000010715	ints9	100	81.307	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0005515	protein binding	16239144.28396433.	IPI	Function
GO:0005634	nucleus	23904267.	IDA	Component
GO:0005654	nucleoplasm	-	IDA	Component
GO:0005654	nucleoplasm	-	TAS	Component
GO:0005829	cytosol	-	IDA	Component
GO:0016180	snRNA processing	16239144.	IDA	Process
GO:0032039	integrator complex	16239144.	IDA	Component
GO:0042795	snRNA transcription by RNA polymerase II	-	TAS	Process