EuRBPDB

Description

RBDs

RBPome

Expression

Transcripts

Gene Model

GWAS

PPI

Paralogs

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000104859 (Gene tree)
Gene ID: 11129
Gene Symbol: CLASRP
Alias: SWAP2|CLASP|SFRS16
Full Name: CLK4 associating serine/arginine rich protein
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Plus strand
Length: 31,917 bases
Position: chr19:45,039,040-45,070,956
Accession: 17731
RBP type: canonical RBP
Summary: (CLK4 Associating Serine/Arginine Rich Protein) is a Protein Coding gene. Among its related pathways are mRNA Splicing - Major Pathway. An important paralog of this gene is SFSWAP.

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000438702	DRY_EERY	PF09750.9	6.3e-42	1	1
ENSP00000221455	DRY_EERY	PF09750.9	6.6e-42	1	1
ENSP00000465562	DRY_EERY	PF09750.9	4.9e-20	1	1
ENSP00000375815	DRY_EERY	PF09750.9	9.6e-13	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000592876	CLASRP-216	751	-	-	- (aa)	-	-
ENST00000591410	CLASRP-213	572	-	ENSP00000465750	81 (aa)	-	K7EKR8
ENST00000544944	CLASRP-204	2769	-	ENSP00000438702	655 (aa)	-	F5H0Q6
ENST00000588936	CLASRP-212	590	-	ENSP00000465562	86 (aa)	-	K7EKC9
ENST00000585615	CLASRP-206	633	-	-	- (aa)	-	-
ENST00000391952	CLASRP-202	2213	-	ENSP00000375814	594 (aa)	-	Q8N2M8
ENST00000391953	CLASRP-203	1941	XM_011526397	ENSP00000375815	612 (aa)	XP_011524699	Q8N2M8
ENST00000585432	CLASRP-205	290	-	-	- (aa)	-	-
ENST00000587472	CLASRP-208	345	-	-	- (aa)	-	-
ENST00000591904	CLASRP-214	506	-	ENSP00000467177	131 (aa)	-	K7EP11
ENST00000592056	CLASRP-215	582	-	-	- (aa)	-	-
ENST00000588247	CLASRP-211	599	-	-	- (aa)	-	-
ENST00000588016	CLASRP-209	967	-	-	- (aa)	-	-
ENST00000221455	CLASRP-201	2234	XM_011526396	ENSP00000221455	674 (aa)	XP_011524698	A0A0A0MQS2
ENST00000588070	CLASRP-210	445	-	-	- (aa)	-	-
ENST00000587112	CLASRP-207	867	-	ENSP00000466371	188 (aa)	-	K7EM61

Gene Model

Click here to download ENSG00000104859's gene model file

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000104859	rs76856627	19	45040497	?	Family history of Alzheimer's disease	29777097			EFO_0009268
ENSG00000104859	rs112481437	19	45045877	?	Family history of Alzheimer's disease	29777097			EFO_0009268
ENSG00000104859	rs147188206	19	45049329	?	Family history of Alzheimer's disease	29777097			EFO_0009268
ENSG00000104859	rs147188206	19	45049329	?	Alzheimer's disease or family history of Alzheimer's disease	29777097			EFO_0000249\|EFO_0009268
ENSG00000104859	rs76856627	19	45040497	?	Alzheimer's disease or family history of Alzheimer's disease	29777097			EFO_0000249\|EFO_0009268
ENSG00000104859	rs112481437	19	45045877	?	Alzheimer's disease or family history of Alzheimer's disease	29777097			EFO_0000249\|EFO_0009268
ENSG00000104859	rs112481437	19	45045877	A	Alzheimer's disease or family history of Alzheimer's disease	30617256	NR z-unit increase	8.578216	EFO_0000249\|EFO_0009268
ENSG00000104859	rs76856627	19	45040497	G	Alzheimer's disease or family history of Alzheimer's disease	30617256	NR z-unit increase	8.306043	EFO_0000249\|EFO_0009268
ENSG00000104859	rs147188206	19	45049329	C	Alzheimer's disease or family history of Alzheimer's disease	30617256	NR z-unit increase	7.5976734	EFO_0000249\|EFO_0009268

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000104859's network

* RBP PPI network refers to all genes directly bind to RBP

Paralogs

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy
ENSG00000104859	CLASRP	53	47.826	ENSG00000061936	SFSWAP	68	37.805

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000104859	CLASRP	100	91.860	ENSAPOG00000016578	clasrp	59	82.840	Acanthochromis_polyacanthus
ENSG00000104859	CLASRP	100	100.000	ENSAMEG00000012638	CLASRP	52	97.458	Ailuropoda_melanoleuca
ENSG00000104859	CLASRP	53	45.652	ENSACIG00000009240	-	64	37.805	Amphilophus_citrinellus
ENSG00000104859	CLASRP	100	90.698	ENSACIG00000014149	clasrp	53	83.136	Amphilophus_citrinellus
ENSG00000104859	CLASRP	100	91.860	ENSAOCG00000005893	clasrp	58	82.840	Amphiprion_ocellaris
ENSG00000104859	CLASRP	100	91.860	ENSAPEG00000024441	clasrp	59	82.840	Amphiprion_percula
ENSG00000104859	CLASRP	100	90.698	ENSATEG00000013691	clasrp	59	83.728	Anabas_testudineus
ENSG00000104859	CLASRP	100	100.000	ENSACAG00000004151	CLASRP	52	92.012	Anolis_carolinensis
ENSG00000104859	CLASRP	100	100.000	ENSANAG00000023127	CLASRP	100	98.817	Aotus_nancymaae
ENSG00000104859	CLASRP	100	90.698	ENSACLG00000016357	clasrp	58	82.544	Astatotilapia_calliptera
ENSG00000104859	CLASRP	100	100.000	ENSBTAG00000013697	CLASRP	100	97.033	Bos_taurus
ENSG00000104859	CLASRP	100	100.000	ENSCJAG00000012926	CLASRP	100	99.112	Callithrix_jacchus
ENSG00000104859	CLASRP	100	100.000	ENSCAFG00000004587	CLASRP	79	98.930	Canis_familiaris
ENSG00000104859	CLASRP	100	100.000	ENSCAFG00020012303	-	96	98.492	Canis_lupus_dingo
ENSG00000104859	CLASRP	100	100.000	ENSCHIG00000024252	CLASRP	50	91.247	Capra_hircus
ENSG00000104859	CLASRP	100	100.000	ENSTSYG00000012066	CLASRP	100	97.781	Carlito_syrichta
ENSG00000104859	CLASRP	100	98.837	ENSCAPG00000014238	CLASRP	55	97.740	Cavia_aperea
ENSG00000104859	CLASRP	100	98.837	ENSCPOG00000010282	CLASRP	53	97.746	Cavia_porcellus
ENSG00000104859	CLASRP	100	100.000	ENSCCAG00000029385	CLASRP	100	98.373	Cebus_capucinus
ENSG00000104859	CLASRP	100	100.000	ENSCATG00000040827	CLASRP	100	99.260	Cercocebus_atys
ENSG00000104859	CLASRP	100	98.837	ENSCLAG00000002206	CLASRP	53	97.465	Chinchilla_lanigera
ENSG00000104859	CLASRP	100	100.000	ENSCSAG00000003231	CLASRP	79	99.733	Chlorocebus_sabaeus
ENSG00000104859	CLASRP	100	100.000	ENSCPBG00000014391	CLASRP	70	92.308	Chrysemys_picta_bellii
ENSG00000104859	CLASRP	100	56.977	ENSCING00000005087	-	65	55.102	Ciona_intestinalis
ENSG00000104859	CLASRP	100	58.140	ENSCSAVG00000002630	-	73	64.286	Ciona_savignyi
ENSG00000104859	CLASRP	100	100.000	ENSCANG00000028388	CLASRP	100	99.115	Colobus_angolensis_palliatus
ENSG00000104859	CLASRP	100	100.000	ENSCGRG00001015861	Clasrp	56	97.761	Cricetulus_griseus_chok1gshd
ENSG00000104859	CLASRP	100	90.698	ENSCSEG00000016914	clasrp	59	80.769	Cynoglossus_semilaevis
ENSG00000104859	CLASRP	79	35.616	ENSCVAG00000001208	-	71	38.750	Cyprinodon_variegatus
ENSG00000104859	CLASRP	100	88.372	ENSCVAG00000004010	clasrp	59	79.882	Cyprinodon_variegatus
ENSG00000104859	CLASRP	100	93.023	ENSDARG00000061742	clasrp	52	81.416	Danio_rerio
ENSG00000104859	CLASRP	100	100.000	ENSDNOG00000039537	CLASRP	73	94.737	Dasypus_novemcinctus
ENSG00000104859	CLASRP	100	100.000	ENSDORG00000003450	Clasrp	54	98.310	Dipodomys_ordii
ENSG00000104859	CLASRP	60	40.385	FBgn0003638	su(w[a])	59	35.789	Drosophila_melanogaster
ENSG00000104859	CLASRP	100	87.209	ENSEBUG00000013993	clasrp	69	70.732	Eptatretus_burgeri
ENSG00000104859	CLASRP	100	100.000	ENSEASG00005013755	CLASRP	53	85.714	Equus_asinus_asinus
ENSG00000104859	CLASRP	100	100.000	ENSECAG00000009232	CLASRP	76	99.652	Equus_caballus
ENSG00000104859	CLASRP	100	93.023	ENSELUG00000014585	clasrp	67	66.279	Esox_lucius
ENSG00000104859	CLASRP	100	100.000	ENSFCAG00000033941	CLASRP	100	96.755	Felis_catus
ENSG00000104859	CLASRP	100	98.837	ENSFDAG00000018622	CLASRP	60	97.740	Fukomys_damarensis
ENSG00000104859	CLASRP	100	89.535	ENSFHEG00000006269	clasrp	91	78.994	Fundulus_heteroclitus
ENSG00000104859	CLASRP	83	90.141	ENSGMOG00000007125	clasrp	67	82.555	Gadus_morhua
ENSG00000104859	CLASRP	100	89.535	ENSGAFG00000012489	clasrp	82	85.057	Gambusia_affinis
ENSG00000104859	CLASRP	83	90.141	ENSGACG00000009826	clasrp	50	80.805	Gasterosteus_aculeatus
ENSG00000104859	CLASRP	100	100.000	ENSGGOG00000003384	CLASRP	100	100.000	Gorilla_gorilla
ENSG00000104859	CLASRP	100	90.698	ENSHBUG00000002053	clasrp	70	82.544	Haplochromis_burtoni
ENSG00000104859	CLASRP	100	98.837	ENSHGLG00000019534	CLASRP	54	98.592	Heterocephalus_glaber_female
ENSG00000104859	CLASRP	100	98.837	ENSHGLG00100012344	CLASRP	52	93.239	Heterocephalus_glaber_male
ENSG00000104859	CLASRP	100	89.535	ENSHCOG00000007529	clasrp	59	79.882	Hippocampus_comes
ENSG00000104859	CLASRP	100	91.860	ENSIPUG00000011928	clasrp	52	79.882	Ictalurus_punctatus
ENSG00000104859	CLASRP	100	100.000	ENSSTOG00000009069	CLASRP	100	96.633	Ictidomys_tridecemlineatus
ENSG00000104859	CLASRP	100	100.000	ENSJJAG00000016124	-	96	99.510	Jaculus_jaculus
ENSG00000104859	CLASRP	100	90.698	ENSKMAG00000020973	clasrp	67	73.810	Kryptolebias_marmoratus
ENSG00000104859	CLASRP	100	90.698	ENSLBEG00000021054	clasrp	52	81.657	Labrus_bergylta
ENSG00000104859	CLASRP	100	91.860	ENSLACG00000000893	CLASRP	53	86.391	Latimeria_chalumnae
ENSG00000104859	CLASRP	100	95.349	ENSLOCG00000014647	clasrp	51	85.799	Lepisosteus_oculatus
ENSG00000104859	CLASRP	100	100.000	ENSLAFG00000008075	CLASRP	53	98.873	Loxodonta_africana
ENSG00000104859	CLASRP	100	100.000	ENSMFAG00000032121	CLASRP	100	99.260	Macaca_fascicularis
ENSG00000104859	CLASRP	100	100.000	ENSMMUG00000014155	CLASRP	100	99.408	Macaca_mulatta
ENSG00000104859	CLASRP	100	100.000	ENSMNEG00000000043	CLASRP	100	99.112	Macaca_nemestrina
ENSG00000104859	CLASRP	100	100.000	ENSMLEG00000034161	CLASRP	100	99.391	Mandrillus_leucophaeus
ENSG00000104859	CLASRP	100	90.698	ENSMAMG00000011689	clasrp	51	82.840	Mastacembelus_armatus
ENSG00000104859	CLASRP	100	90.698	ENSMZEG00005016696	clasrp	54	82.544	Maylandia_zebra
ENSG00000104859	CLASRP	53	45.652	ENSMZEG00005009699	-	67	37.975	Maylandia_zebra
ENSG00000104859	CLASRP	100	100.000	ENSMAUG00000000378	Clasrp	53	98.028	Mesocricetus_auratus
ENSG00000104859	CLASRP	100	100.000	ENSMICG00000006996	CLASRP	100	98.071	Microcebus_murinus
ENSG00000104859	CLASRP	100	100.000	ENSMOCG00000007548	Clasrp	53	98.310	Microtus_ochrogaster
ENSG00000104859	CLASRP	100	90.698	ENSMMOG00000012523	clasrp	72	85.000	Mola_mola
ENSG00000104859	CLASRP	100	98.837	ENSMODG00000020854	CLASRP	52	95.044	Monodelphis_domestica
ENSG00000104859	CLASRP	100	89.535	ENSMALG00000012365	clasrp	71	82.544	Monopterus_albus
ENSG00000104859	CLASRP	100	100.000	MGP_CAROLIEiJ_G0029299	Clasrp	53	98.310	Mus_caroli
ENSG00000104859	CLASRP	53	47.826	MGP_CAROLIEiJ_G0027780	Sfswap	68	37.805	Mus_caroli
ENSG00000104859	CLASRP	100	100.000	ENSMUSG00000061028	Clasrp	96	98.995	Mus_musculus
ENSG00000104859	CLASRP	53	47.826	ENSMUSG00000029439	Sfswap	68	37.805	Mus_musculus
ENSG00000104859	CLASRP	53	47.826	MGP_PahariEiJ_G0024360	Sfswap	68	37.805	Mus_pahari
ENSG00000104859	CLASRP	100	100.000	MGP_PahariEiJ_G0021159	Clasrp	53	98.310	Mus_pahari
ENSG00000104859	CLASRP	53	47.826	MGP_SPRETEiJ_G0028779	Sfswap	68	37.805	Mus_spretus
ENSG00000104859	CLASRP	100	100.000	MGP_SPRETEiJ_G0030383	Clasrp	53	98.310	Mus_spretus
ENSG00000104859	CLASRP	100	95.441	ENSMLUG00000002165	CLASRP	100	92.353	Myotis_lucifugus
ENSG00000104859	CLASRP	100	100.000	ENSNGAG00000016249	Clasrp	52	98.817	Nannospalax_galili
ENSG00000104859	CLASRP	100	90.698	ENSNBRG00000004382	clasrp	68	82.544	Neolamprologus_brichardi
ENSG00000104859	CLASRP	100	85.513	ENSNLEG00000001811	CLASRP	100	85.513	Nomascus_leucogenys
ENSG00000104859	CLASRP	100	80.153	ENSMEUG00000009998	CLASRP	54	86.761	Notamacropus_eugenii
ENSG00000104859	CLASRP	100	98.837	ENSOPRG00000008066	CLASRP	100	95.556	Ochotona_princeps
ENSG00000104859	CLASRP	100	98.837	ENSODEG00000008407	CLASRP	53	97.183	Octodon_degus
ENSG00000104859	CLASRP	100	90.698	ENSONIG00000003756	clasrp	51	82.249	Oreochromis_niloticus
ENSG00000104859	CLASRP	100	100.000	ENSOCUG00000004711	CLASRP	78	96.884	Oryctolagus_cuniculus
ENSG00000104859	CLASRP	100	90.698	ENSORLG00000006568	clasrp	53	79.882	Oryzias_latipes
ENSG00000104859	CLASRP	100	90.698	ENSORLG00020003213	clasrp	54	79.472	Oryzias_latipes_hni
ENSG00000104859	CLASRP	100	90.698	ENSORLG00015005655	clasrp	54	79.179	Oryzias_latipes_hsok
ENSG00000104859	CLASRP	100	90.698	ENSOMEG00000013102	clasrp	51	80.178	Oryzias_melastigma
ENSG00000104859	CLASRP	100	100.000	ENSOGAG00000034160	CLASRP	100	97.059	Otolemur_garnettii
ENSG00000104859	CLASRP	100	100.000	ENSOARG00000009616	CLASRP	51	99.112	Ovis_aries
ENSG00000104859	CLASRP	100	100.000	ENSPPAG00000040215	CLASRP	100	99.852	Pan_paniscus
ENSG00000104859	CLASRP	100	100.000	ENSPPRG00000017479	CLASRP	100	97.037	Panthera_pardus
ENSG00000104859	CLASRP	100	100.000	ENSPTIG00000006698	-	96	98.492	Panthera_tigris_altaica
ENSG00000104859	CLASRP	100	100.000	ENSPTRG00000022583	CLASRP	100	99.704	Pan_troglodytes
ENSG00000104859	CLASRP	100	100.000	ENSPANG00000012804	CLASRP	100	99.408	Papio_anubis
ENSG00000104859	CLASRP	100	94.186	ENSPKIG00000011266	clasrp	71	81.065	Paramormyrops_kingsleyae
ENSG00000104859	CLASRP	100	98.837	ENSPSIG00000013177	CLASRP	52	89.941	Pelodiscus_sinensis
ENSG00000104859	CLASRP	53	47.826	ENSPMGG00000008093	-	68	38.462	Periophthalmus_magnuspinnatus
ENSG00000104859	CLASRP	100	89.535	ENSPMGG00000014094	clasrp	77	78.022	Periophthalmus_magnuspinnatus
ENSG00000104859	CLASRP	100	100.000	ENSPEMG00000017845	Clasrp	53	98.028	Peromyscus_maniculatus_bairdii
ENSG00000104859	CLASRP	100	60.622	ENSPMAG00000000177	-	98	60.622	Petromyzon_marinus
ENSG00000104859	CLASRP	100	98.837	ENSPCIG00000022909	CLASRP	60	95.211	Phascolarctos_cinereus
ENSG00000104859	CLASRP	100	89.535	ENSPFOG00000010596	clasrp	51	78.761	Poecilia_formosa
ENSG00000104859	CLASRP	100	89.535	ENSPLAG00000019619	clasrp	86	78.994	Poecilia_latipinna
ENSG00000104859	CLASRP	100	89.535	ENSPMEG00000016136	clasrp	50	78.994	Poecilia_mexicana
ENSG00000104859	CLASRP	100	89.535	ENSPREG00000001075	clasrp	56	75.652	Poecilia_reticulata
ENSG00000104859	CLASRP	100	100.000	ENSPPYG00000010104	CLASRP	100	99.556	Pongo_abelii
ENSG00000104859	CLASRP	100	100.000	ENSPCAG00000010871	CLASRP	53	87.360	Procavia_capensis
ENSG00000104859	CLASRP	100	100.000	ENSPCOG00000018016	CLASRP	100	97.640	Propithecus_coquereli
ENSG00000104859	CLASRP	100	100.000	ENSPVAG00000015954	CLASRP	100	96.471	Pteropus_vampyrus
ENSG00000104859	CLASRP	100	90.698	ENSPNYG00000006221	clasrp	60	82.544	Pundamilia_nyererei
ENSG00000104859	CLASRP	100	93.023	ENSPNAG00000019075	clasrp	52	76.627	Pygocentrus_nattereri
ENSG00000104859	CLASRP	100	100.000	ENSRNOG00000046000	Clasrp	53	98.310	Rattus_norvegicus
ENSG00000104859	CLASRP	100	74.046	ENSRBIG00000042924	CLASRP	54	69.822	Rhinopithecus_bieti
ENSG00000104859	CLASRP	100	100.000	ENSRROG00000045419	CLASRP	100	92.899	Rhinopithecus_roxellana
ENSG00000104859	CLASRP	100	100.000	ENSSBOG00000029935	-	97	99.000	Saimiri_boliviensis_boliviensis
ENSG00000104859	CLASRP	100	98.837	ENSSHAG00000004444	-	69	95.614	Sarcophilus_harrisii
ENSG00000104859	CLASRP	100	91.860	ENSSFOG00015006361	clasrp	52	82.544	Scleropages_formosus
ENSG00000104859	CLASRP	100	89.535	ENSSMAG00000013333	clasrp	53	81.953	Scophthalmus_maximus
ENSG00000104859	CLASRP	100	82.558	ENSSDUG00000018560	clasrp	57	80.286	Seriola_dumerili
ENSG00000104859	CLASRP	100	90.698	ENSSLDG00000020726	clasrp	60	82.571	Seriola_lalandi_dorsalis
ENSG00000104859	CLASRP	100	98.837	ENSSPUG00000010734	CLASRP	61	90.828	Sphenodon_punctatus
ENSG00000104859	CLASRP	100	91.860	ENSSPAG00000008665	clasrp	51	83.136	Stegastes_partitus
ENSG00000104859	CLASRP	100	100.000	ENSSSCG00000034231	-	96	99.497	Sus_scrofa
ENSG00000104859	CLASRP	100	90.698	ENSTRUG00000009842	clasrp	85	80.769	Takifugu_rubripes
ENSG00000104859	CLASRP	100	88.372	ENSTNIG00000007734	clasrp	51	80.473	Tetraodon_nigroviridis
ENSG00000104859	CLASRP	83	100.000	ENSTBEG00000001906	CLASRP	62	100.000	Tupaia_belangeri
ENSG00000104859	CLASRP	100	100.000	ENSUAMG00000023365	-	96	98.995	Ursus_americanus
ENSG00000104859	CLASRP	100	100.000	ENSUMAG00000023392	CLASRP	84	99.336	Ursus_maritimus
ENSG00000104859	CLASRP	100	100.000	ENSVVUG00000008161	CLASRP	97	93.514	Vulpes_vulpes
ENSG00000104859	CLASRP	100	96.512	ENSXETG00000019073	clasrp	50	85.207	Xenopus_tropicalis
ENSG00000104859	CLASRP	100	89.535	ENSXMAG00000018599	clasrp	51	78.698	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0005515	protein binding	27173435.	IPI	Function
GO:0005634	nucleus	-	IDA	Component
GO:0005654	nucleoplasm	-	IDA	Component
GO:0006397	mRNA processing	-	IEA	Process
GO:0008380	RNA splicing	-	IEA	Process