EuRBPDB

Description

RBDs

RBPome

Literatures

Expression

Transcripts

Gene Model

Pathways

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000105618 (Gene tree)
Gene ID: 26121
Gene Symbol: PRPF31
Alias: NY-BR-99|PRP31|hPrp31|SNRNP61|RP11
Full Name: pre-mRNA processing factor 31
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Plus strand
Length: 16,344 bases
Position: chr19:54,115,376-54,131,719
Accession: 15446
RBP type: canonical RBP
Summary: This gene encodes a component of the spliceosome complex and is one of several retinitis pigmentosa-causing genes. When the gene product is added to the spliceosome complex, activation occurs.[provided by RefSeq, Jan 2009]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000324122	Prp31_C	PF09785.9	3.6e-45	1	1
ENSP00000375635	Prp31_C	PF09785.9	3.6e-45	1	1
ENSP00000405166	Prp31_C	PF09785.9	2.3e-33	1	1
ENSP00000405166	Nop	PF01798.18	2.2e-83	1	1
ENSP00000324122	Nop	PF01798.18	2.3e-83	1	1
ENSP00000375635	Nop	PF01798.18	1.9e-79	1	1
ENSP00000395894	Nop	PF01798.18	1.4e-64	1	1
ENSP00000408980	Nop	PF01798.18	3.7e-61	1	1
ENSP00000395089	Nop	PF01798.18	2.6e-57	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
22681889	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts	4SURIC & HEK293	2012 May	Baltz AG	DOI: 10.1016/j.molcel.2012.05.021
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
29431736	Capturing the interactome of newly transcribed RNA	PolyT-RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
22658674	Insights into RNA biology from an atlas of mammalian mRNA-binding proteins	RIC & Hela	2012 May 31	Castello A	DOI: 10.1016/j.cell.2012.04.031
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30352994	Discovery of RNA-binding proteins and characterization of their dynamic responses by enhanced RNA interactome capture	RIC & Jurkat	2018 Oct 23	Perez-Perri JI	DOI:10.1038/s41467-018-06557-8

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
12374753	Hierarchical, clustered protein interactions with U4/U6 snRNA: a biochemical role for U4/U6 proteins.	EMBO J	2002 Oct 15	Nottrott S	-
26161500	A composite double-/single-stranded RNA-binding region in protein Prp3 supports tri-snRNP stability and splicing.	Elife	2015 Jul 10	Liu S	doi: 10.7554/eLife.07320.
30099644	A novel mutation in the PRPF31 in a North Indian adRP family with incomplete penetrance.	Doc Ophthalmol	2018 Oct	Bhatia S	doi: 10.1007/s10633-018-9654-x
26503251	Assembly and dynamics of the U4/U6 di-snRNP by single-molecule FRET.	Nucleic Acids Res	2015 Dec 15	Hardin JW	doi: 10.1093/nar/gkv1011
16857676	RNA structural requirements for the association of the spliceosomal hPrp31 protein with the U4 and U4atac small nuclear ribonucleoproteins.	J Biol Chem	2006 Sep 22	Schultz A	-
17412961	Binding of the human Prp31 Nop domain to a composite RNA-protein platform in U4 snRNP.	Science	2007 Apr 6	Liu S	-
21784869	Structural basis for the dual U4 and U4atac snRNA-binding specificity of spliceosomal protein hPrp31.	RNA	2011 Sep	Liu S	doi: 10.1261/rna.2690611
21385873	CTNNBL1 is a novel nuclear localization sequence-binding protein that recognizes RNA-splicing factors CDC5L and Prp31.	J Biol Chem	2011 May 13	Ganesh K	doi: 10.1074/jbc.M110.208769

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000466404	PRPF31-207	1837	-	-	- (aa)	-	-
ENST00000419967	PRPF31-203	2269	-	ENSP00000405166	491 (aa)	-	Q8WWY3
ENST00000498612	PRPF31-209	881	-	-	- (aa)	-	-
ENST00000321030	PRPF31-201	2126	XM_006723137	ENSP00000324122	499 (aa)	XP_006723200	Q8WWY3
ENST00000447810	PRPF31-206	854	-	ENSP00000395089	260 (aa)	-	E7EU94
ENST00000445811	PRPF31-205	928	-	ENSP00000395894	284 (aa)	-	E7EN72
ENST00000391755	PRPF31-202	1767	-	ENSP00000375635	493 (aa)	-	E7EVX8
ENST00000467851	PRPF31-208	289	-	-	- (aa)	-	-
ENST00000445124	PRPF31-204	886	-	ENSP00000408980	276 (aa)	-	E7ESX0

Gene Model

Click here to download ENSG00000105618's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa03040	Spliceosome	KEGG

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000105618	Triglycerides	7.3930000E-005	-

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000105618	rs254271	19	54127382	?	Change in HbA1c levels in response to metformin treatment in type 2 diabetes	29650774			EFO_0004541\|EFO_0001360\|GO_1901558

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000105618's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000105618	PRPF31	93	85.745	ENSAPOG00000020310	prpf31	97	85.745	Acanthochromis_polyacanthus
ENSG00000105618	PRPF31	100	99.648	ENSAMEG00000004502	PRPF31	100	99.399	Ailuropoda_melanoleuca
ENSG00000105618	PRPF31	99	83.168	ENSACIG00000006591	prpf31	91	86.177	Amphilophus_citrinellus
ENSG00000105618	PRPF31	99	83.773	ENSAOCG00000021333	prpf31	93	85.652	Amphiprion_ocellaris
ENSG00000105618	PRPF31	99	83.773	ENSAPEG00000008035	prpf31	93	85.652	Amphiprion_percula
ENSG00000105618	PRPF31	99	82.970	ENSATEG00000022705	prpf31	91	85.745	Anabas_testudineus
ENSG00000105618	PRPF31	96	94.990	ENSACAG00000016061	PRPF31	94	95.745	Anolis_carolinensis
ENSG00000105618	PRPF31	84	99.761	ENSANAG00000020822	PRPF31	100	99.761	Aotus_nancymaae
ENSG00000105618	PRPF31	99	83.532	ENSACLG00000021238	prpf31	91	85.961	Astatotilapia_calliptera
ENSG00000105618	PRPF31	99	82.961	ENSAMXG00000012329	prpf31	93	84.017	Astyanax_mexicanus
ENSG00000105618	PRPF31	100	99.648	ENSBTAG00000007757	PRPF31	100	99.399	Bos_taurus
ENSG00000105618	PRPF31	100	41.980	WBGene00022458	prp-31	91	47.174	Caenorhabditis_elegans
ENSG00000105618	PRPF31	100	100.000	ENSCJAG00000018525	PRPF31	100	100.000	Callithrix_jacchus
ENSG00000105618	PRPF31	100	99.648	ENSCAFG00000002700	PRPF31	100	99.599	Canis_familiaris
ENSG00000105618	PRPF31	100	99.648	ENSCAFG00020018376	PRPF31	100	99.599	Canis_lupus_dingo
ENSG00000105618	PRPF31	100	99.648	ENSCHIG00000021020	PRPF31	94	95.532	Capra_hircus
ENSG00000105618	PRPF31	100	98.998	ENSTSYG00000013569	PRPF31	100	98.998	Carlito_syrichta
ENSG00000105618	PRPF31	100	99.296	ENSCAPG00000013797	PRPF31	100	98.597	Cavia_aperea
ENSG00000105618	PRPF31	100	99.296	ENSCPOG00000011507	PRPF31	100	98.597	Cavia_porcellus
ENSG00000105618	PRPF31	100	100.000	ENSCCAG00000020552	-	100	100.000	Cebus_capucinus
ENSG00000105618	PRPF31	92	89.107	ENSCCAG00000022236	-	98	89.107	Cebus_capucinus
ENSG00000105618	PRPF31	100	99.800	ENSCATG00000006020	PRPF31	100	99.800	Cercocebus_atys
ENSG00000105618	PRPF31	100	98.944	ENSCLAG00000001700	PRPF31	100	98.397	Chinchilla_lanigera
ENSG00000105618	PRPF31	100	100.000	ENSCSAG00000001903	PRPF31	100	100.000	Chlorocebus_sabaeus
ENSG00000105618	PRPF31	54	99.286	ENSCHOG00000008394	-	54	99.286	Choloepus_hoffmanni
ENSG00000105618	PRPF31	89	95.711	ENSCPBG00000011670	PRPF31	92	95.711	Chrysemys_picta_bellii
ENSG00000105618	PRPF31	83	56.561	ENSCING00000002806	-	85	57.979	Ciona_intestinalis
ENSG00000105618	PRPF31	98	62.772	ENSCSAVG00000010862	-	87	63.812	Ciona_savignyi
ENSG00000105618	PRPF31	100	99.800	ENSCANG00000029967	PRPF31	100	99.800	Colobus_angolensis_palliatus
ENSG00000105618	PRPF31	100	99.399	ENSCGRG00001004873	Prpf31	100	99.399	Cricetulus_griseus_chok1gshd
ENSG00000105618	PRPF31	94	98.929	ENSCGRG00000012910	Prpf31	100	98.929	Cricetulus_griseus_crigri
ENSG00000105618	PRPF31	98	82.400	ENSCSEG00000018961	prpf31	91	85.033	Cynoglossus_semilaevis
ENSG00000105618	PRPF31	99	84.990	ENSCVAG00000000226	prpf31	93	85.931	Cyprinodon_variegatus
ENSG00000105618	PRPF31	99	82.213	ENSDARG00000095904	prpf31	91	85.345	Danio_rerio
ENSG00000105618	PRPF31	100	99.399	ENSDNOG00000032884	PRPF31	99	99.399	Dasypus_novemcinctus
ENSG00000105618	PRPF31	100	99.198	ENSDORG00000008022	Prpf31	100	99.198	Dipodomys_ordii
ENSG00000105618	PRPF31	98	60.239	FBgn0036487	Prp31	89	63.252	Drosophila_melanogaster
ENSG00000105618	PRPF31	83	98.291	ENSETEG00000017891	PRPF31	82	98.291	Echinops_telfairi
ENSG00000105618	PRPF31	62	75.141	ENSEBUG00000004819	prpf31	90	55.820	Eptatretus_burgeri
ENSG00000105618	PRPF31	100	99.648	ENSEASG00005021593	PRPF31	100	99.599	Equus_asinus_asinus
ENSG00000105618	PRPF31	100	99.648	ENSECAG00000020667	PRPF31	100	99.599	Equus_caballus
ENSG00000105618	PRPF31	77	90.885	ENSEEUG00000006128	PRPF31	100	90.885	Erinaceus_europaeus
ENSG00000105618	PRPF31	99	82.271	ENSELUG00000014820	prpf31	94	83.051	Esox_lucius
ENSG00000105618	PRPF31	100	99.648	ENSFCAG00000014037	PRPF31	100	99.599	Felis_catus
ENSG00000105618	PRPF31	100	99.296	ENSFDAG00000011961	PRPF31	100	98.798	Fukomys_damarensis
ENSG00000105618	PRPF31	82	89.944	ENSFHEG00000003642	prpf31	66	88.268	Fundulus_heteroclitus
ENSG00000105618	PRPF31	99	81.386	ENSGMOG00000005345	prpf31	89	83.766	Gadus_morhua
ENSG00000105618	PRPF31	99	84.584	ENSGAFG00000013128	prpf31	94	85.714	Gambusia_affinis
ENSG00000105618	PRPF31	99	81.584	ENSGACG00000011464	prpf31	91	84.449	Gasterosteus_aculeatus
ENSG00000105618	PRPF31	96	94.979	ENSGAGG00000000670	PRPF31	94	95.957	Gopherus_agassizii
ENSG00000105618	PRPF31	100	100.000	ENSGGOG00000016516	PRPF31	100	100.000	Gorilla_gorilla
ENSG00000105618	PRPF31	99	83.333	ENSHBUG00000005311	prpf31	91	85.745	Haplochromis_burtoni
ENSG00000105618	PRPF31	100	98.592	ENSHGLG00000010504	PRPF31	100	98.196	Heterocephalus_glaber_female
ENSG00000105618	PRPF31	100	98.592	ENSHGLG00100005911	PRPF31	100	87.221	Heterocephalus_glaber_male
ENSG00000105618	PRPF31	99	81.386	ENSHCOG00000020890	prpf31	91	84.233	Hippocampus_comes
ENSG00000105618	PRPF31	99	81.782	ENSIPUG00000000171	prpf31	91	84.449	Ictalurus_punctatus
ENSG00000105618	PRPF31	100	99.296	ENSSTOG00000001287	PRPF31	100	99.198	Ictidomys_tridecemlineatus
ENSG00000105618	PRPF31	100	99.648	ENSJJAG00000015594	Prpf31	100	99.599	Jaculus_jaculus
ENSG00000105618	PRPF31	99	82.376	ENSKMAG00000004967	prpf31	91	85.313	Kryptolebias_marmoratus
ENSG00000105618	PRPF31	99	82.574	ENSLBEG00000017225	prpf31	91	85.097	Labrus_bergylta
ENSG00000105618	PRPF31	93	81.385	ENSLACG00000009449	PRPF31	93	81.385	Latimeria_chalumnae
ENSG00000105618	PRPF31	99	76.699	ENSLOCG00000000007	prpf31	90	79.574	Lepisosteus_oculatus
ENSG00000105618	PRPF31	100	99.648	ENSLAFG00000004559	PRPF31	100	99.399	Loxodonta_africana
ENSG00000105618	PRPF31	100	100.000	ENSMFAG00000001108	PRPF31	100	100.000	Macaca_fascicularis
ENSG00000105618	PRPF31	100	100.000	ENSMMUG00000022297	PRPF31	100	100.000	Macaca_mulatta
ENSG00000105618	PRPF31	100	100.000	ENSMNEG00000035943	PRPF31	100	100.000	Macaca_nemestrina
ENSG00000105618	PRPF31	100	100.000	ENSMLEG00000031953	PRPF31	100	100.000	Mandrillus_leucophaeus
ENSG00000105618	PRPF31	99	83.168	ENSMAMG00000019433	prpf31	91	85.714	Mastacembelus_armatus
ENSG00000105618	PRPF31	99	83.532	ENSMZEG00005016314	prpf31	91	85.961	Maylandia_zebra
ENSG00000105618	PRPF31	100	99.296	ENSMAUG00000011581	Prpf31	100	99.198	Mesocricetus_auratus
ENSG00000105618	PRPF31	100	99.648	ENSMICG00000002355	PRPF31	100	99.399	Microcebus_murinus
ENSG00000105618	PRPF31	100	99.399	ENSMOCG00000002128	Prpf31	100	99.399	Microtus_ochrogaster
ENSG00000105618	PRPF31	99	81.386	ENSMMOG00000016451	prpf31	91	84.881	Mola_mola
ENSG00000105618	PRPF31	100	97.194	ENSMODG00000004098	PRPF31	100	97.194	Monodelphis_domestica
ENSG00000105618	PRPF31	99	82.591	ENSMALG00000009251	prpf31	93	83.948	Monopterus_albus
ENSG00000105618	PRPF31	100	99.399	MGP_CAROLIEiJ_G0029094	Prpf31	100	99.399	Mus_caroli
ENSG00000105618	PRPF31	100	98.998	ENSMUSG00000008373	Prpf31	100	98.998	Mus_musculus
ENSG00000105618	PRPF31	100	98.998	MGP_PahariEiJ_G0020963	Prpf31	100	98.998	Mus_pahari
ENSG00000105618	PRPF31	100	99.296	MGP_SPRETEiJ_G0030147	Prpf31	99	99.595	Mus_spretus
ENSG00000105618	PRPF31	100	99.648	ENSMPUG00000010341	PRPF31	100	99.599	Mustela_putorius_furo
ENSG00000105618	PRPF31	100	97.101	ENSMLUG00000016862	PRPF31	99	96.787	Myotis_lucifugus
ENSG00000105618	PRPF31	100	98.798	ENSNGAG00000024131	Prpf31	100	98.798	Nannospalax_galili
ENSG00000105618	PRPF31	99	83.333	ENSNBRG00000002354	prpf31	91	85.745	Neolamprologus_brichardi
ENSG00000105618	PRPF31	100	89.409	ENSNLEG00000006261	-	100	89.409	Nomascus_leucogenys
ENSG00000105618	PRPF31	98	96.063	ENSMEUG00000002943	PRPF31	93	89.141	Notamacropus_eugenii
ENSG00000105618	PRPF31	58	99.298	ENSOPRG00000000055	PRPF31	100	98.962	Ochotona_princeps
ENSG00000105618	PRPF31	100	99.648	ENSODEG00000000855	PRPF31	100	98.798	Octodon_degus
ENSG00000105618	PRPF31	99	83.532	ENSONIG00000006574	prpf31	91	85.961	Oreochromis_niloticus
ENSG00000105618	PRPF31	93	95.437	ENSOANG00000009386	-	93	78.517	Ornithorhynchus_anatinus
ENSG00000105618	PRPF31	94	90.234	ENSOCUG00000002027	PRPF31	94	90.234	Oryctolagus_cuniculus
ENSG00000105618	PRPF31	99	84.211	ENSORLG00000011189	prpf31	93	85.498	Oryzias_latipes
ENSG00000105618	PRPF31	99	83.976	ENSORLG00020007965	prpf31	93	85.435	Oryzias_latipes_hni
ENSG00000105618	PRPF31	99	81.854	ENSORLG00015013676	prpf31	91	85.498	Oryzias_latipes_hsok
ENSG00000105618	PRPF31	99	81.657	ENSOMEG00000010384	prpf31	91	85.097	Oryzias_melastigma
ENSG00000105618	PRPF31	62	99.674	ENSOGAG00000006936	PRPF31	100	99.674	Otolemur_garnettii
ENSG00000105618	PRPF31	95	99.262	ENSOARG00000003033	PRPF31	95	86.638	Ovis_aries
ENSG00000105618	PRPF31	100	100.000	ENSPPAG00000032209	PRPF31	100	100.000	Pan_paniscus
ENSG00000105618	PRPF31	100	99.648	ENSPPRG00000011686	PRPF31	100	99.599	Panthera_pardus
ENSG00000105618	PRPF31	100	99.648	ENSPTIG00000008467	PRPF31	100	99.599	Panthera_tigris_altaica
ENSG00000105618	PRPF31	100	100.000	ENSPTRG00000045480	-	100	100.000	Pan_troglodytes
ENSG00000105618	PRPF31	100	100.000	ENSPTRG00000011443	PRPF31	100	100.000	Pan_troglodytes
ENSG00000105618	PRPF31	100	100.000	ENSPANG00000025402	PRPF31	100	100.000	Papio_anubis
ENSG00000105618	PRPF31	99	82.122	ENSPKIG00000011812	prpf31	91	85.622	Paramormyrops_kingsleyae
ENSG00000105618	PRPF31	65	95.356	ENSPSIG00000003405	PRPF31	95	95.806	Pelodiscus_sinensis
ENSG00000105618	PRPF31	88	71.605	ENSPMGG00000012045	prpf31	83	76.238	Periophthalmus_magnuspinnatus
ENSG00000105618	PRPF31	100	94.188	ENSPEMG00000011678	Prpf31	100	94.188	Peromyscus_maniculatus_bairdii
ENSG00000105618	PRPF31	100	97.194	ENSPCIG00000014820	PRPF31	100	97.194	Phascolarctos_cinereus
ENSG00000105618	PRPF31	99	83.168	ENSPFOG00000008822	prpf31	91	85.961	Poecilia_formosa
ENSG00000105618	PRPF31	99	82.574	ENSPLAG00000013314	prpf31	91	85.313	Poecilia_latipinna
ENSG00000105618	PRPF31	99	84.990	ENSPMEG00000017707	prpf31	93	86.147	Poecilia_mexicana
ENSG00000105618	PRPF31	99	82.574	ENSPREG00000007764	prpf31	91	85.313	Poecilia_reticulata
ENSG00000105618	PRPF31	100	100.000	ENSPPYG00000010371	PRPF31	100	100.000	Pongo_abelii
ENSG00000105618	PRPF31	100	75.150	ENSPCAG00000011872	PRPF31	100	75.150	Procavia_capensis
ENSG00000105618	PRPF31	100	99.648	ENSPCOG00000020393	PRPF31	100	99.399	Propithecus_coquereli
ENSG00000105618	PRPF31	100	99.648	ENSPVAG00000015562	PRPF31	100	98.798	Pteropus_vampyrus
ENSG00000105618	PRPF31	99	83.135	ENSPNYG00000002232	prpf31	91	85.529	Pundamilia_nyererei
ENSG00000105618	PRPF31	99	81.693	ENSPNAG00000003485	prpf31	91	84.979	Pygocentrus_nattereri
ENSG00000105618	PRPF31	100	99.399	ENSRNOG00000061039	Prpf31	100	99.399	Rattus_norvegicus
ENSG00000105618	PRPF31	100	99.800	ENSRBIG00000034963	PRPF31	100	99.800	Rhinopithecus_bieti
ENSG00000105618	PRPF31	100	99.800	ENSRROG00000038740	PRPF31	100	99.800	Rhinopithecus_roxellana
ENSG00000105618	PRPF31	66	31.700	YGR091W	-	71	31.073	Saccharomyces_cerevisiae
ENSG00000105618	PRPF31	100	100.000	ENSSBOG00000028915	PRPF31	100	100.000	Saimiri_boliviensis_boliviensis
ENSG00000105618	PRPF31	100	97.194	ENSSHAG00000009065	PRPF31	100	97.194	Sarcophilus_harrisii
ENSG00000105618	PRPF31	99	82.583	ENSSFOG00015000288	prpf31	92	85.684	Scleropages_formosus
ENSG00000105618	PRPF31	99	82.376	ENSSMAG00000013211	prpf31	91	85.097	Scophthalmus_maximus
ENSG00000105618	PRPF31	99	84.040	ENSSDUG00000008360	prpf31	93	84.017	Seriola_dumerili
ENSG00000105618	PRPF31	99	74.749	ENSSLDG00000002851	prpf31	91	77.243	Seriola_lalandi_dorsalis
ENSG00000105618	PRPF31	96	94.154	ENSSPUG00000008622	PRPF31	94	94.894	Sphenodon_punctatus
ENSG00000105618	PRPF31	99	78.571	ENSSPAG00000022547	prpf31	92	81.224	Stegastes_partitus
ENSG00000105618	PRPF31	100	98.597	ENSSSCG00000003263	PRPF31	100	98.597	Sus_scrofa
ENSG00000105618	PRPF31	99	81.151	ENSTRUG00000015769	prpf31	91	84.416	Takifugu_rubripes
ENSG00000105618	PRPF31	99	81.102	ENSTNIG00000008083	prpf31	91	84.120	Tetraodon_nigroviridis
ENSG00000105618	PRPF31	94	86.200	ENSTTRG00000006566	PRPF31	94	84.926	Tursiops_truncatus
ENSG00000105618	PRPF31	100	99.648	ENSUAMG00000005241	PRPF31	100	99.599	Ursus_americanus
ENSG00000105618	PRPF31	100	99.648	ENSUMAG00000011212	PRPF31	100	99.599	Ursus_maritimus
ENSG00000105618	PRPF31	100	99.648	ENSVVUG00000008257	PRPF31	100	99.599	Vulpes_vulpes
ENSG00000105618	PRPF31	95	91.139	ENSXETG00000010916	prpf31	94	92.291	Xenopus_tropicalis
ENSG00000105618	PRPF31	99	84.381	ENSXCOG00000019456	prpf31	94	85.281	Xiphophorus_couchianus
ENSG00000105618	PRPF31	99	84.584	ENSXMAG00000012272	prpf31	94	85.498	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000244	spliceosomal tri-snRNP complex assembly	11867543.	IDA	Process
GO:0000244	spliceosomal tri-snRNP complex assembly	15257298.	IMP	Process
GO:0000398	mRNA splicing, via spliceosome	21873635.	IBA	Process
GO:0000398	mRNA splicing, via spliceosome	15257298.	IC	Process
GO:0000398	mRNA splicing, via spliceosome	11867543.28781166.	IDA	Process
GO:0000398	mRNA splicing, via spliceosome	-	TAS	Process
GO:0003723	RNA binding	22658674.22681889.	HDA	Function
GO:0005515	protein binding	21385873.22365833.23793891.25416956.25910212.27107012.	IPI	Function
GO:0005634	nucleus	26912367.28781166.	IDA	Component
GO:0005654	nucleoplasm	-	TAS	Component
GO:0005684	U2-type spliceosomal complex	17412961.	IC	Component
GO:0005687	U4 snRNP	21873635.	IBA	Component
GO:0005687	U4 snRNP	17412961.	IDA	Component
GO:0005690	U4atac snRNP	21784869.	IDA	Component
GO:0005690	U4atac snRNP	17412961.	TAS	Component
GO:0015030	Cajal body	11867543.	IDA	Component
GO:0016607	nuclear speck	11867543.	IDA	Component
GO:0030621	U4 snRNA binding	16857676.	IDA	Function
GO:0030622	U4atac snRNA binding	16857676.21784869.	IDA	Function
GO:0043021	ribonucleoprotein complex binding	11867543.	IDA	Function
GO:0046540	U4/U6 x U5 tri-snRNP complex	11867543.23793891.26912367.	IDA	Component
GO:0048254	snoRNA localization	17636026.	IMP	Process
GO:0070990	snRNP binding	17412961.	IPI	Function
GO:0071005	U2-type precatalytic spliceosome	28781166.	IDA	Component
GO:0071166	ribonucleoprotein complex localization	17636026.	IMP	Process
GO:0071339	MLL1 complex	15960975.	IDA	Component