EuRBPDB

Basic Information
Cancer Related Information

Description

RBDs

Expression

Transcripts

Gene Model

Phenotypes

GWAS

PPI

Paralogs

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000105865 (Gene tree)
Gene ID: 11062
Gene Symbol: DUS4L
Alias: PP35|DUS4
Full Name: dihydrouridine synthase 4 like
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Plus strand
Length: 15,040 bases
Position: chr7:107,563,484-107,578,523
Accession: 21517
RBP type: canonical RBP
Summary: (Dihydrouridine Synthase 4 Like) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include oxidoreductase activity and FMN binding. An important paralog of this gene is DUS1L.

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000265720	Dus	PF01207.17	9.9e-74	1	1

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000467916	DUS4L-207	744	-	-	- (aa)	-	-
ENST00000422290	DUS4L-202	1610	-	ENSP00000402887	90 (aa)	-	F2Z2E4
ENST00000497798	DUS4L-210	583	-	-	- (aa)	-	-
ENST00000485825	DUS4L-209	989	-	-	- (aa)	-	-
ENST00000265720	DUS4L-201	2220	XM_005250125	ENSP00000265720	317 (aa)	XP_005250182	O95620
ENST00000431839	DUS4L-203	1375	-	ENSP00000388904	90 (aa)	-	F2Z2E4
ENST00000436411	DUS4L-204	2280	-	ENSP00000412739	90 (aa)	-	F2Z2E4
ENST00000443233	DUS4L-205	1676	-	ENSP00000388061	119 (aa)	-	F8WEL2
ENST00000471763	DUS4L-208	2148	-	-	- (aa)	-	-
ENST00000498786	DUS4L-211	491	-	-	- (aa)	-	-
ENST00000458611	DUS4L-206	857	-	ENSP00000399375	48 (aa)	-	F8WFE3

Gene Model

Click here to download ENSG00000105865's gene model file

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000105865	Osteoarthritis	6E-8	21068099

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000105865	rs4730250	7	107567250	G	Osteoarthritis	21068099	[1.10-1.22]	1.15	EFO_0002506

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000105865's network

* RBP PPI network refers to all genes directly bind to RBP

Paralogs

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy
ENSG00000105865	DUS4L	76	44.565	ENSG00000169718	DUS1L	91	36.179

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000105865	DUS4L	94	71.812	ENSAPOG00000015063	dus4l	95	71.812	Acanthochromis_polyacanthus
ENSG00000105865	DUS4L	100	95.798	ENSAMEG00000013535	DUS4L	98	94.322	Ailuropoda_melanoleuca
ENSG00000105865	DUS4L	94	71.477	ENSACIG00000017392	dus4l	95	71.477	Amphilophus_citrinellus
ENSG00000105865	DUS4L	94	72.148	ENSAOCG00000007191	dus4l	95	72.148	Amphiprion_ocellaris
ENSG00000105865	DUS4L	94	72.148	ENSAPEG00000015296	dus4l	95	72.148	Amphiprion_percula
ENSG00000105865	DUS4L	94	71.812	ENSATEG00000009040	dus4l	95	71.812	Anabas_testudineus
ENSG00000105865	DUS4L	95	80.921	ENSAPLG00000007641	DUS4L	99	80.921	Anas_platyrhynchos
ENSG00000105865	DUS4L	98	77.492	ENSACAG00000015202	DUS4L	96	77.492	Anolis_carolinensis
ENSG00000105865	DUS4L	96	96.382	ENSANAG00000037839	DUS4L	99	96.382	Aotus_nancymaae
ENSG00000105865	DUS4L	94	71.477	ENSACLG00000021844	dus4l	95	71.477	Astatotilapia_calliptera
ENSG00000105865	DUS4L	94	70.470	ENSAMXG00000032924	dus4l	99	70.470	Astyanax_mexicanus
ENSG00000105865	DUS4L	100	92.437	ENSBTAG00000021849	DUS4L	99	91.798	Bos_taurus
ENSG00000105865	DUS4L	88	49.286	WBGene00016674	C45G9.2	99	49.286	Caenorhabditis_elegans
ENSG00000105865	DUS4L	100	96.667	ENSCJAG00000016323	DUS4L	100	96.667	Callithrix_jacchus
ENSG00000105865	DUS4L	100	95.798	ENSCAFG00000003919	DUS4L	100	93.691	Canis_familiaris
ENSG00000105865	DUS4L	100	94.958	ENSCAFG00020023124	DUS4L	100	93.375	Canis_lupus_dingo
ENSG00000105865	DUS4L	100	94.958	ENSCHIG00000010888	DUS4L	99	93.060	Capra_hircus
ENSG00000105865	DUS4L	100	94.118	ENSTSYG00000010065	DUS4L	100	92.429	Carlito_syrichta
ENSG00000105865	DUS4L	67	97.500	ENSCAPG00000007215	DUS4L	100	74.820	Cavia_aperea
ENSG00000105865	DUS4L	100	94.118	ENSCPOG00000002384	DUS4L	100	93.060	Cavia_porcellus
ENSG00000105865	DUS4L	100	97.778	ENSCCAG00000027960	DUS4L	100	97.778	Cebus_capucinus
ENSG00000105865	DUS4L	100	99.160	ENSCATG00000031611	DUS4L	100	98.889	Cercocebus_atys
ENSG00000105865	DUS4L	100	94.958	ENSCLAG00000012135	DUS4L	100	93.060	Chinchilla_lanigera
ENSG00000105865	DUS4L	100	100.000	ENSCSAG00000011370	DUS4L	100	98.738	Chlorocebus_sabaeus
ENSG00000105865	DUS4L	100	93.277	ENSCHOG00000006848	DUS4L	99	89.224	Choloepus_hoffmanni
ENSG00000105865	DUS4L	100	81.388	ENSCPBG00000000863	DUS4L	100	81.388	Chrysemys_picta_bellii
ENSG00000105865	DUS4L	94	53.535	ENSCING00000001869	-	96	53.535	Ciona_intestinalis
ENSG00000105865	DUS4L	95	56.333	ENSCSAVG00000005308	-	99	56.333	Ciona_savignyi
ENSG00000105865	DUS4L	100	99.160	ENSCANG00000024456	DUS4L	100	98.889	Colobus_angolensis_palliatus
ENSG00000105865	DUS4L	100	89.916	ENSCGRG00001014181	Dus4l	100	89.905	Cricetulus_griseus_chok1gshd
ENSG00000105865	DUS4L	100	89.916	ENSCGRG00000000384	Dus4l	100	89.905	Cricetulus_griseus_crigri
ENSG00000105865	DUS4L	94	71.477	ENSCSEG00000018179	dus4l	94	71.477	Cynoglossus_semilaevis
ENSG00000105865	DUS4L	85	69.307	ENSCVAG00000018366	-	89	69.307	Cyprinodon_variegatus
ENSG00000105865	DUS4L	94	71.812	ENSCVAG00000010487	dus4l	94	71.812	Cyprinodon_variegatus
ENSG00000105865	DUS4L	94	70.470	ENSDARG00000006567	dus4l	97	70.470	Danio_rerio
ENSG00000105865	DUS4L	100	94.118	ENSDNOG00000030725	DUS4L	100	93.691	Dasypus_novemcinctus
ENSG00000105865	DUS4L	100	90.221	ENSDORG00000010587	Dus4l	100	90.221	Dipodomys_ordii
ENSG00000105865	DUS4L	97	42.812	FBgn0032750	CG10495	80	42.812	Drosophila_melanogaster
ENSG00000105865	DUS4L	99	90.678	ENSETEG00000004577	-	99	66.222	Echinops_telfairi
ENSG00000105865	DUS4L	85	74.257	ENSEBUG00000008924	dus4l	95	62.207	Eptatretus_burgeri
ENSG00000105865	DUS4L	100	97.479	ENSEASG00005017480	DUS4L	100	93.375	Equus_asinus_asinus
ENSG00000105865	DUS4L	100	95.798	ENSECAG00000014852	DUS4L	100	93.060	Equus_caballus
ENSG00000105865	DUS4L	88	87.342	ENSEEUG00000001308	-	100	67.500	Erinaceus_europaeus
ENSG00000105865	DUS4L	94	69.900	ENSELUG00000017740	dus4l	94	69.900	Esox_lucius
ENSG00000105865	DUS4L	100	96.639	ENSFCAG00000041439	DUS4L	100	94.953	Felis_catus
ENSG00000105865	DUS4L	100	77.743	ENSFALG00000010246	DUS4L	99	77.743	Ficedula_albicollis
ENSG00000105865	DUS4L	100	91.167	ENSFDAG00000010206	DUS4L	100	91.167	Fukomys_damarensis
ENSG00000105865	DUS4L	94	71.141	ENSFHEG00000020124	dus4l	95	71.141	Fundulus_heteroclitus
ENSG00000105865	DUS4L	94	69.128	ENSGMOG00000001452	dus4l	96	69.128	Gadus_morhua
ENSG00000105865	DUS4L	100	75.710	ENSGALG00000023661	DUS4L	99	75.710	Gallus_gallus
ENSG00000105865	DUS4L	94	70.134	ENSGAFG00000010054	dus4l	95	70.134	Gambusia_affinis
ENSG00000105865	DUS4L	94	70.470	ENSGACG00000008772	dus4l	94	70.470	Gasterosteus_aculeatus
ENSG00000105865	DUS4L	100	78.992	ENSGAGG00000015768	DUS4L	100	78.992	Gopherus_agassizii
ENSG00000105865	DUS4L	100	99.685	ENSGGOG00000003821	DUS4L	100	99.685	Gorilla_gorilla
ENSG00000105865	DUS4L	94	71.477	ENSHBUG00000015255	dus4l	95	71.477	Haplochromis_burtoni
ENSG00000105865	DUS4L	100	91.597	ENSHGLG00000018976	DUS4L	100	89.590	Heterocephalus_glaber_female
ENSG00000105865	DUS4L	100	91.597	ENSHGLG00100002604	DUS4L	100	89.590	Heterocephalus_glaber_male
ENSG00000105865	DUS4L	98	67.846	ENSHCOG00000015919	dus4l	98	67.846	Hippocampus_comes
ENSG00000105865	DUS4L	97	68.627	ENSIPUG00000014454	dus4l	99	70.134	Ictalurus_punctatus
ENSG00000105865	DUS4L	100	93.277	ENSSTOG00000000212	DUS4L	100	93.060	Ictidomys_tridecemlineatus
ENSG00000105865	DUS4L	98	91.935	ENSJJAG00000013626	Dus4l	100	92.208	Jaculus_jaculus
ENSG00000105865	DUS4L	94	70.707	ENSKMAG00000013719	dus4l	94	70.707	Kryptolebias_marmoratus
ENSG00000105865	DUS4L	94	71.477	ENSLBEG00000018142	dus4l	95	71.477	Labrus_bergylta
ENSG00000105865	DUS4L	94	66.964	ENSLACG00000000451	DUS4L	96	73.778	Latimeria_chalumnae
ENSG00000105865	DUS4L	94	74.503	ENSLOCG00000015815	dus4l	93	74.503	Lepisosteus_oculatus
ENSG00000105865	DUS4L	100	92.437	ENSLAFG00000000968	DUS4L	100	91.772	Loxodonta_africana
ENSG00000105865	DUS4L	100	100.000	ENSMFAG00000003759	DUS4L	100	100.000	Macaca_fascicularis
ENSG00000105865	DUS4L	100	100.000	ENSMNEG00000040594	DUS4L	100	100.000	Macaca_nemestrina
ENSG00000105865	DUS4L	100	100.000	ENSMLEG00000037658	DUS4L	100	100.000	Mandrillus_leucophaeus
ENSG00000105865	DUS4L	94	71.812	ENSMAMG00000007717	dus4l	85	71.812	Mastacembelus_armatus
ENSG00000105865	DUS4L	88	71.583	ENSMZEG00005014697	dus4l	94	71.583	Maylandia_zebra
ENSG00000105865	DUS4L	75	80.169	ENSMGAG00000009714	DUS4L	96	80.169	Meleagris_gallopavo
ENSG00000105865	DUS4L	100	90.756	ENSMAUG00000016651	Dus4l	100	89.905	Mesocricetus_auratus
ENSG00000105865	DUS4L	100	96.667	ENSMICG00000042944	-	100	96.667	Microcebus_murinus
ENSG00000105865	DUS4L	88	93.671	ENSMICG00000027213	-	100	70.662	Microcebus_murinus
ENSG00000105865	DUS4L	100	90.756	ENSMOCG00000019344	Dus4l	100	89.905	Microtus_ochrogaster
ENSG00000105865	DUS4L	94	66.330	ENSMMOG00000011517	dus4l	94	66.330	Mola_mola
ENSG00000105865	DUS4L	100	86.555	ENSMODG00000016361	DUS4L	100	84.543	Monodelphis_domestica
ENSG00000105865	DUS4L	94	71.141	ENSMALG00000002457	dus4l	94	71.141	Monopterus_albus
ENSG00000105865	DUS4L	100	94.118	MGP_CAROLIEiJ_G0017680	Dus4l	98	90.823	Mus_caroli
ENSG00000105865	DUS4L	100	93.277	ENSMUSG00000020648	Dus4l	98	90.506	Mus_musculus
ENSG00000105865	DUS4L	100	91.597	MGP_PahariEiJ_G0029438	Dus4l	98	89.873	Mus_pahari
ENSG00000105865	DUS4L	100	92.437	MGP_SPRETEiJ_G0018522	Dus4l	98	90.506	Mus_spretus
ENSG00000105865	DUS4L	96	94.737	ENSMPUG00000018247	DUS4L	99	94.737	Mustela_putorius_furo
ENSG00000105865	DUS4L	100	93.277	ENSMLUG00000002731	DUS4L	99	91.525	Myotis_lucifugus
ENSG00000105865	DUS4L	100	90.756	ENSNGAG00000022335	Dus4l	100	90.536	Nannospalax_galili
ENSG00000105865	DUS4L	94	71.141	ENSNBRG00000013582	dus4l	95	71.141	Neolamprologus_brichardi
ENSG00000105865	DUS4L	100	99.160	ENSNLEG00000008716	DUS4L	100	99.054	Nomascus_leucogenys
ENSG00000105865	DUS4L	66	93.671	ENSMEUG00000000187	-	100	70.408	Notamacropus_eugenii
ENSG00000105865	DUS4L	100	89.076	ENSOPRG00000005394	DUS4L	100	87.234	Ochotona_princeps
ENSG00000105865	DUS4L	100	92.114	ENSODEG00000001582	DUS4L	100	92.114	Octodon_degus
ENSG00000105865	DUS4L	94	71.812	ENSONIG00000004993	dus4l	95	71.812	Oreochromis_niloticus
ENSG00000105865	DUS4L	96	82.237	ENSOANG00000003179	DUS4L	99	82.237	Ornithorhynchus_anatinus
ENSG00000105865	DUS4L	100	93.277	ENSOCUG00000012784	DUS4L	100	93.060	Oryctolagus_cuniculus
ENSG00000105865	DUS4L	94	71.141	ENSORLG00000008306	dus4l	93	71.141	Oryzias_latipes
ENSG00000105865	DUS4L	94	71.477	ENSORLG00020020542	dus4l	93	71.477	Oryzias_latipes_hni
ENSG00000105865	DUS4L	94	71.141	ENSORLG00015001648	dus4l	93	71.141	Oryzias_latipes_hsok
ENSG00000105865	DUS4L	94	71.141	ENSOMEG00000017582	dus4l	95	71.141	Oryzias_melastigma
ENSG00000105865	DUS4L	100	96.639	ENSOGAG00000013113	DUS4L	98	94.953	Otolemur_garnettii
ENSG00000105865	DUS4L	100	94.958	ENSOARG00000005713	DUS4L	98	93.060	Ovis_aries
ENSG00000105865	DUS4L	100	100.000	ENSPPAG00000031482	DUS4L	100	100.000	Pan_paniscus
ENSG00000105865	DUS4L	100	95.798	ENSPPRG00000010523	DUS4L	100	94.637	Panthera_pardus
ENSG00000105865	DUS4L	100	95.798	ENSPTIG00000005318	DUS4L	100	94.637	Panthera_tigris_altaica
ENSG00000105865	DUS4L	100	100.000	ENSPTRG00000019579	DUS4L	100	100.000	Pan_troglodytes
ENSG00000105865	DUS4L	100	99.160	ENSPANG00000007111	DUS4L	100	98.889	Papio_anubis
ENSG00000105865	DUS4L	88	72.760	ENSPKIG00000016429	dus4l	88	72.760	Paramormyrops_kingsleyae
ENSG00000105865	DUS4L	100	81.073	ENSPSIG00000013488	DUS4L	100	81.073	Pelodiscus_sinensis
ENSG00000105865	DUS4L	94	71.812	ENSPMGG00000012731	dus4l	95	71.812	Periophthalmus_magnuspinnatus
ENSG00000105865	DUS4L	100	91.597	ENSPEMG00000022807	Dus4l	100	89.905	Peromyscus_maniculatus_bairdii
ENSG00000105865	DUS4L	100	86.555	ENSPCIG00000005163	DUS4L	100	87.308	Phascolarctos_cinereus
ENSG00000105865	DUS4L	98	68.489	ENSPFOG00000004246	dus4l	98	68.489	Poecilia_formosa
ENSG00000105865	DUS4L	94	70.805	ENSPLAG00000021398	dus4l	94	70.805	Poecilia_latipinna
ENSG00000105865	DUS4L	98	68.489	ENSPMEG00000010911	dus4l	98	68.489	Poecilia_mexicana
ENSG00000105865	DUS4L	94	70.805	ENSPREG00000021419	dus4l	94	70.805	Poecilia_reticulata
ENSG00000105865	DUS4L	100	100.000	ENSPPYG00000017901	DUS4L	100	97.792	Pongo_abelii
ENSG00000105865	DUS4L	76	97.531	ENSPCAG00000012668	-	76	97.531	Procavia_capensis
ENSG00000105865	DUS4L	100	97.778	ENSPCOG00000015747	DUS4L	100	97.778	Propithecus_coquereli
ENSG00000105865	DUS4L	100	96.639	ENSPVAG00000014548	DUS4L	100	77.918	Pteropus_vampyrus
ENSG00000105865	DUS4L	87	71.841	ENSPNYG00000015730	dus4l	93	71.841	Pundamilia_nyererei
ENSG00000105865	DUS4L	94	71.141	ENSPNAG00000021961	dus4l	99	71.141	Pygocentrus_nattereri
ENSG00000105865	DUS4L	100	92.437	ENSRNOG00000008155	Dus4l	98	90.190	Rattus_norvegicus
ENSG00000105865	DUS4L	100	100.000	ENSRBIG00000025544	DUS4L	100	100.000	Rhinopithecus_bieti
ENSG00000105865	DUS4L	100	100.000	ENSRROG00000000241	DUS4L	100	100.000	Rhinopithecus_roxellana
ENSG00000105865	DUS4L	94	41.479	YLR405W	-	84	41.479	Saccharomyces_cerevisiae
ENSG00000105865	DUS4L	96	97.368	ENSSBOG00000025576	DUS4L	99	97.368	Saimiri_boliviensis_boliviensis
ENSG00000105865	DUS4L	100	86.555	ENSSHAG00000012813	DUS4L	98	85.174	Sarcophilus_harrisii
ENSG00000105865	DUS4L	95	71.761	ENSSFOG00015005943	dus4l	99	71.761	Scleropages_formosus
ENSG00000105865	DUS4L	94	70.134	ENSSMAG00000018502	dus4l	94	70.134	Scophthalmus_maximus
ENSG00000105865	DUS4L	85	70.297	ENSSDUG00000002389	dus4l	50	73.228	Seriola_dumerili
ENSG00000105865	DUS4L	94	71.477	ENSSLDG00000008740	dus4l	96	71.477	Seriola_lalandi_dorsalis
ENSG00000105865	DUS4L	79	86.842	ENSSARG00000008057	-	66	87.931	Sorex_araneus
ENSG00000105865	DUS4L	100	78.233	ENSSPUG00000019140	DUS4L	99	78.233	Sphenodon_punctatus
ENSG00000105865	DUS4L	94	71.812	ENSSPAG00000020826	dus4l	95	71.812	Stegastes_partitus
ENSG00000105865	DUS4L	96	93.750	ENSSSCG00000028433	DUS4L	99	94.265	Sus_scrofa
ENSG00000105865	DUS4L	100	79.180	ENSTGUG00000003124	DUS4L	100	79.180	Taeniopygia_guttata
ENSG00000105865	DUS4L	94	71.812	ENSTRUG00000016285	dus4l	98	71.812	Takifugu_rubripes
ENSG00000105865	DUS4L	99	74.051	ENSTBEG00000001401	DUS4L	99	74.051	Tupaia_belangeri
ENSG00000105865	DUS4L	87	79.422	ENSTTRG00000006833	DUS4L	100	79.422	Tursiops_truncatus
ENSG00000105865	DUS4L	90	93.827	ENSUAMG00000005960	-	91	95.000	Ursus_americanus
ENSG00000105865	DUS4L	100	96.639	ENSUMAG00000018230	DUS4L	99	94.620	Ursus_maritimus
ENSG00000105865	DUS4L	100	95.798	ENSVPAG00000008640	DUS4L	100	92.722	Vicugna_pacos
ENSG00000105865	DUS4L	100	94.958	ENSVVUG00000021846	DUS4L	100	93.060	Vulpes_vulpes
ENSG00000105865	DUS4L	89	78.445	ENSXETG00000005925	dus4l	99	78.445	Xenopus_tropicalis
ENSG00000105865	DUS4L	85	69.307	ENSXCOG00000012786	dus4l	90	67.308	Xiphophorus_couchianus
ENSG00000105865	DUS4L	94	69.799	ENSXMAG00000008454	dus4l	96	69.799	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0002943	tRNA dihydrouridine synthesis	-	IEA	Process
GO:0017150	tRNA dihydrouridine synthase activity	21873635.	IBA	Function
GO:0050660	flavin adenine dinucleotide binding	-	IEA	Function
GO:0055114	oxidation-reduction process	-	IEA	Process

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
28415823	Recurrent fusion RNA DUS4L-BCAP29 in non-cancer human tissues and cells.	Oncotarget	2017 May 9	Tang Y	doi: 10.18632/oncotarget.16329.

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
ACC	chr7	107577529	Missense_Mutation	novel	I308T	0.42
BLCA	chr7	107575254	Silent	rs752975974	V141V	0.53
BRCA	chr7	107576517	Frame_Shift_Del	novel	*I211Yfs3**	0.11	Dus
BRCA	chr7	107573863	Intron	novel		0.44
CESC	chr7	107573766	Missense_Mutation	rs768814850	R101C	0.31	Dus
CESC	chr7	107573863	Intron	novel		0.35
CESC	chr7	107577414	Missense_Mutation	novel	E270K	0.41	Dus
CESC	chr7	107573862	Intron	novel		0.15
COAD	chr7	107573863	Intron	novel		0.15
COAD	chr7	107573863	Intron	novel		0.3
COAD	chr7	107577374	Silent	NA	T256T	0.3
COAD	chr7	107573863	Intron	novel		0.39
COAD	chr7	107573863	Intron	novel		0.2
COAD	chr7	107575169	Intron	NA		0.23
COAD	chr7	107573863	Intron	novel		0.15
COAD	chr7	107573766	Missense_Mutation	rs768814850	R101C	0.21	Dus
COAD	chr7	107573863	Intron	novel		0.14
COAD	chr7	107575296	Silent	NA	V155V	0.36
COAD	chr7	107573786	Silent	rs773307945	A107A	0.1
ESCA	chr7	107577389	Missense_Mutation	novel	I261M	0.09	Dus
GBM	chr7	107573777	Missense_Mutation	NA	C104W	0.38	Dus
GBM	chr7	107576460	Missense_Mutation	novel	E192K	0.28	Dus
GBM	chr7	107577510	Missense_Mutation	NA	S302A	0.28
GBM	chr7	107577453	Missense_Mutation	novel	M283V	0.22	Dus
HNSC	chr7	107567119	Missense_Mutation	novel	D17Y	0.56
HNSC	chr7	107571144	Splice_Site	rs533668907	X39_splice	0.18
KIRC	chr7	107567059	5'UTR	novel		0.28
KIRP	chr7	107576427	Missense_Mutation	NA	S181T	0.27	Dus
KIRP	chr7	107576584	Missense_Mutation	novel	G233V	0.16	Dus
LGG	chr7	107575217	Missense_Mutation	novel	C129S	0.12	Dus
LIHC	chr7	107576527	Missense_Mutation	NA	I214T	0.46	Dus
LIHC	chr7	107577511	Nonsense_Mutation	novel	S302*	0.25
LIHC	chr7	107567118	Silent	NA	K16K	0.05
LUAD	chr7	107576420	Silent	NA	T178T	0.47
LUAD	chr7	107573861	Intron	novel		0.31
LUSC	chr7	107571166	Silent	novel	V46V	0.42
LUSC	chr7	107571209	Missense_Mutation	novel	A61T	0.25	Dus
LUSC	chr7	107575293	Silent	novel	S154S	0.2
LUSC	chr7	107575236	Silent	novel	E135E	0.28
OV	chr7	107577594	3'UTR	novel		0.29
PAAD	chr7	107573761	Missense_Mutation	novel	A99V	0.17	Dus
READ	chr7	107576574	Missense_Mutation	rs149644587	R230W	0.27	Dus
READ	chr7	107575286	Missense_Mutation	NA	G152A	0.31	Dus
SKCM	chr7	107571249	Missense_Mutation	novel	E74G	0.15	Dus
SKCM	chr7	107571211	Silent	NA	A61A	0.33
SKCM	chr7	107577505	Missense_Mutation	rs184033937	A300V	0.29
SKCM	chr7	107573863	Intron	novel		0.26
STAD	chr7	107573863	Intron	novel		0.17
STAD	chr7	107576436	Missense_Mutation	NA	T184A	0.09	Dus
STAD	chr7	107573863	Intron	novel		0.24
STAD	chr7	107573863	Intron	novel		0.25
STAD	chr7	107573863	Intron	novel		0.16
STAD	chr7	107573739	Missense_Mutation	rs200901846	D92N	0.26	Dus
STAD	chr7	107577487	Frame_Shift_Del	NA	*R296Gfs13**	0.25
STAD	chr7	107573863	Intron	novel		0.17
STAD	chr7	107567148	Missense_Mutation	novel	Q26H	0.2
STAD	chr7	107575304	Missense_Mutation	novel	K158T	0.16	Dus
STAD	chr7	107573863	Intron	novel		0.17
STAD	chr7	107573863	Intron	novel		0.17
UCEC	chr7	107575159	Intron	novel		0.18
UCEC	chr7	107577652	3'UTR	novel		0.12
UCEC	chr7	107573766	Missense_Mutation	rs768814850	R101C	0.41	Dus
UCEC	chr7	107571252	Missense_Mutation	NA	F75C	0.46	Dus
UCEC	chr7	107577421	Missense_Mutation	novel	G272V	0.21	Dus
UCEC	chr7	107573786	Silent	rs773307945	A107A	0.2
UCEC	chr7	107577505	Missense_Mutation	NA	A300D	0.2
UCEC	chr7	107573863	Intron	novel		0.12
UCEC	chr7	107573863	Intron	novel		0.19
UCEC	chr7	107573863	Intron	novel		0.38
UCEC	chr7	107577494	Silent	novel	R296R	0.4
UCEC	chr7	107576397	Missense_Mutation	novel	L171I	0.1	Dus
UCEC	chr7	107573863	Intron	novel		0.23
UCEC	chr7	107573863	Intron	novel		0.21
UCEC	chr7	107575054	Intron	novel		0.14
UCEC	chr7	107573863	Intron	novel		0.51
UCEC	chr7	107576408	Missense_Mutation	NA	K174N	0.39	Dus
UCEC	chr7	107573863	Intron	novel		0.43
UCEC	chr7	107577487	Frame_Shift_Del	NA	*R296Gfs13**	0.32
UCEC	chr7	107573863	Intron	novel		0.19
UCEC	chr7	107573863	Intron	novel		0.33
UCEC	chr7	107567063	5'UTR	novel		0.11
UCEC	chr7	107577511	Missense_Mutation	novel	S302L	0.27
UCEC	chr7	107573863	Intron	novel		0.32
UCEC	chr7	107575257	Silent	novel	K142K	0.4
UCEC	chr7	107567080	Missense_Mutation	NA	D4N	0.28
UCEC	chr7	107573863	Intron	novel		0.19
UCEC	chr7	107577589	3'UTR	rs779469779		0.32
UCEC	chr7	107573863	Intron	novel		0.09
UCEC	chr7	107577684	3'UTR	novel		0.4
UCEC	chr7	107573863	Intron	novel		0.23
UCEC	chr7	107573863	Intron	novel		0.2

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
ACC	DEL	0.0778	0.12261
DLBC	AMP	0.2917	0.13215
LGG	AMP	0.3041	1.5525e-07
LIHC	DEL	0.0595	0.24831
PAAD	DEL	0.0598	0.049388
PRAD	AMP	0.1382	0.012709
TGCT	AMP	0.62	0.035574
THCA	DEL	0.002	0.27619
UCS	DEL	0.2321	0.10142

Survival Analysis

Cancer	P-value	Q-value
ACC	0.0024	Kaplan-Meier Survival Analysis
SKCM	0.03	Kaplan-Meier Survival Analysis
LUSC	0.044	Kaplan-Meier Survival Analysis
BLCA	0.0085	Kaplan-Meier Survival Analysis
LAML	0.004	Kaplan-Meier Survival Analysis
KICH	0.0025	Kaplan-Meier Survival Analysis
GBM	0.03	Kaplan-Meier Survival Analysis
LGG	0.00042	Kaplan-Meier Survival Analysis
THCA	0.019	Kaplan-Meier Survival Analysis

Drugs

EuRBPDB

Description

RBDs

Expression

Transcripts

Gene Model

Phenotypes

GWAS

PPI

Paralogs

Orthologs

Gene Ontology

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742