EuRBPDB

Description

Ensembl ID: ENSG00000106244 (Gene tree)
Gene ID: 11333
Gene Symbol: PDAP1
Alias: PAP1|PAP|HASPP28
Full Name: PDGFA associated protein 1
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Minus strand
Length: 16,782 bases
Position: chr7:99,392,048-99,408,829
Accession: 14634
RBP type: non-canonical RBP
Summary: The protein encoded by this gene is a phosphoprotein that may upregulate the PDGFA-stimulated growth of fibroblasts and also downregulate the mitogenicity of PDGFB. The encoded protein in rodents has been shown to bind PDGFA with a low affinity. [provided by RefSeq, Dec 2010]

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
22681889	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts	4SURIC & HEK293	2012 May	Baltz AG	DOI: 10.1016/j.molcel.2012.05.021
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
27453046	Comprehensive Identification of RNA-Binding Domains in Human Cells	RIC & Hela	2016 Aug 18	Castello A	DOI: 10.1016/j.molcel.2016.06.029

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000350498	PDAP1-201	2546	-	ENSP00000222968	181 (aa)	-	Q13442
ENST00000426447	PDAP1-202	767	-	ENSP00000411287	39 (aa)	-	F8WBW6
ENST00000626285	PDAP1-205	120	-	ENSP00000486021	39 (aa)	-	F8WBW6
ENST00000488214	PDAP1-203	274	-	-	- (aa)	-	-
ENST00000496335	PDAP1-204	302	-	-	- (aa)	-	-

Gene Model

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000106244	rs140429100	7	99397842	?	Mean corpuscular hemoglobin	30595370			EFO_0004527
ENSG00000106244	rs140429100	7	99397842	?	Red blood cell count	30595370			EFO_0004305

Protein-Protein Interaction (PPI)

Orthologs identified by RBPome

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000106244	PDAP1	100	96.685	ENSMUSG00000029623	Pdap1	100	96.685	Mus_musculus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0003723	RNA binding	22681889.	HDA	Function
GO:0005576	extracellular region	-	TAS	Component
GO:0005829	cytosol	-	IDA	Component
GO:0005886	plasma membrane	-	IDA	Component
GO:0007165	signal transduction	8780057.	TAS	Process
GO:0008283	cell proliferation	8780057.	TAS	Process
GO:0043312	neutrophil degranulation	-	TAS	Process
GO:1904813	ficolin-1-rich granule lumen	-	TAS	Component