EuRBPDB

Basic Information
Cancer Related Information

Description

RBDs

Expression

Transcripts

Gene Model

Pathways

Phenotypes

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000106397 (Gene tree)
Gene ID: 8985
Gene Symbol: PLOD3
Alias: LH3
Full Name: procollagen-lysine,2-oxoglutarate 5-dioxygenase 3
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Minus strand
Length: 12,444 bases
Position: chr7:101,205,977-101,218,420
Accession: 9083
RBP type: canonical RBP
Summary: The protein encoded by this gene is a membrane-bound homodimeric enzyme that is localized to the cisternae of the rough endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VIB have deficiencies in lysyl hydroxylase activity. [provided by RefSeq, Jul 2008]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000407555	2OG-FeII_Oxy	PF03171.20	8.9e-06	1	1
ENSP00000223127	2OG-FeII_Oxy	PF03171.20	4.7e-05	1	1

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000414785	PLOD3-202	539	-	ENSP00000407551	171 (aa)	-	C9JU11
ENST00000478264	PLOD3-213	663	-	-	- (aa)	-	-
ENST00000466881	PLOD3-211	661	-	-	- (aa)	-	-
ENST00000421736	PLOD3-203	809	-	ENSP00000407908	270 (aa)	-	H7C2V1
ENST00000223127	PLOD3-201	2920	-	ENSP00000223127	738 (aa)	-	O60568
ENST00000460475	PLOD3-209	746	-	-	- (aa)	-	-
ENST00000454310	PLOD3-206	1098	-	ENSP00000407555	264 (aa)	-	H7C2S8
ENST00000460132	PLOD3-208	578	-	-	- (aa)	-	-
ENST00000463479	PLOD3-210	505	-	-	- (aa)	-	-
ENST00000456079	PLOD3-207	563	-	ENSP00000416070	75 (aa)	-	C9JIX5
ENST00000440925	PLOD3-205	536	-	ENSP00000394045	66 (aa)	-	H7C0B8
ENST00000487563	PLOD3-215	712	-	-	- (aa)	-	-
ENST00000424135	PLOD3-204	565	-	ENSP00000404799	125 (aa)	-	H7C2A8
ENST00000478082	PLOD3-212	1585	-	-	- (aa)	-	-
ENST00000489927	PLOD3-216	562	-	-	- (aa)	-	-
ENST00000481461	PLOD3-214	564	-	-	- (aa)	-	-

Gene Model

Click here to download ENSG00000106397's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa00310	Lysine degradation	KEGG
hsa00514	Other types of O-glycan biosynthesis	KEGG

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000106397	Platelet Function Tests	6.7100000E-006	-
ENSG00000106397	Platelet Function Tests	9.1000000E-007	-
ENSG00000106397	Platelet Function Tests	6.4300000E-006	-
ENSG00000106397	Platelet Function Tests	7.8400000E-006	-
ENSG00000106397	Platelet Function Tests	9.0100000E-006	-
ENSG00000106397	Platelet Function Tests	5.1800000E-007	-
ENSG00000106397	Platelet Function Tests	1.9000000E-007	-

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000106397's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000106397	PLOD3	98	64.615	ENSAPOG00000013081	plod1a	99	55.050	Acanthochromis_polyacanthus
ENSG00000106397	PLOD3	98	75.385	ENSAPOG00000013652	plod3	97	66.525	Acanthochromis_polyacanthus
ENSG00000106397	PLOD3	98	96.923	ENSAMEG00000002732	PLOD3	100	93.514	Ailuropoda_melanoleuca
ENSG00000106397	PLOD3	98	69.231	ENSAMEG00000009887	PLOD1	97	59.097	Ailuropoda_melanoleuca
ENSG00000106397	PLOD3	98	76.923	ENSAMEG00000013650	PLOD2	95	58.436	Ailuropoda_melanoleuca
ENSG00000106397	PLOD3	98	76.923	ENSACIG00000009256	plod3	96	65.915	Amphilophus_citrinellus
ENSG00000106397	PLOD3	97	62.500	ENSACIG00000007846	plod1a	96	50.282	Amphilophus_citrinellus
ENSG00000106397	PLOD3	98	70.769	ENSACIG00000018677	plod2	100	60.844	Amphilophus_citrinellus
ENSG00000106397	PLOD3	98	64.615	ENSAOCG00000018734	plod1a	99	55.945	Amphiprion_ocellaris
ENSG00000106397	PLOD3	98	75.385	ENSAOCG00000009132	plod3	97	66.102	Amphiprion_ocellaris
ENSG00000106397	PLOD3	98	61.538	ENSAPEG00000006235	plod1a	99	55.761	Amphiprion_percula
ENSG00000106397	PLOD3	98	75.385	ENSAPEG00000020103	plod3	97	66.102	Amphiprion_percula
ENSG00000106397	PLOD3	97	68.750	ENSATEG00000022077	plod1a	96	57.284	Anabas_testudineus
ENSG00000106397	PLOD3	98	76.923	ENSAPLG00000011324	PLOD1	96	60.795	Anas_platyrhynchos
ENSG00000106397	PLOD3	98	78.462	ENSAPLG00000011127	PLOD2	99	59.889	Anas_platyrhynchos
ENSG00000106397	PLOD3	98	83.077	ENSACAG00000003968	PLOD3	97	74.202	Anolis_carolinensis
ENSG00000106397	PLOD3	98	73.846	ENSACAG00000006657	PLOD2	96	57.613	Anolis_carolinensis
ENSG00000106397	PLOD3	98	98.462	ENSANAG00000036204	PLOD3	100	92.141	Aotus_nancymaae
ENSG00000106397	PLOD3	98	66.154	ENSANAG00000026221	PLOD1	100	59.175	Aotus_nancymaae
ENSG00000106397	PLOD3	98	75.385	ENSANAG00000030377	PLOD2	95	59.829	Aotus_nancymaae
ENSG00000106397	PLOD3	98	66.154	ENSACLG00000002498	plod1a	96	56.818	Astatotilapia_calliptera
ENSG00000106397	PLOD3	98	73.846	ENSACLG00000027422	plod2	97	59.918	Astatotilapia_calliptera
ENSG00000106397	PLOD3	98	61.538	ENSAMXG00000014065	plod1a	97	57.644	Astyanax_mexicanus
ENSG00000106397	PLOD3	98	76.923	ENSAMXG00000016685	plod3	98	61.204	Astyanax_mexicanus
ENSG00000106397	PLOD3	98	67.692	ENSBTAG00000002052	PLOD1	99	60.369	Bos_taurus
ENSG00000106397	PLOD3	98	93.846	ENSBTAG00000000342	PLOD3	96	94.708	Bos_taurus
ENSG00000106397	PLOD3	98	76.923	ENSBTAG00000007331	PLOD2	95	59.972	Bos_taurus
ENSG00000106397	PLOD3	98	98.462	ENSCJAG00000016006	PLOD3	100	97.207	Callithrix_jacchus
ENSG00000106397	PLOD3	98	64.615	ENSCJAG00000013459	PLOD1	97	59.375	Callithrix_jacchus
ENSG00000106397	PLOD3	98	76.923	ENSCJAG00000001578	PLOD2	98	58.127	Callithrix_jacchus
ENSG00000106397	PLOD3	98	96.923	ENSCAFG00000013860	PLOD3	100	94.324	Canis_familiaris
ENSG00000106397	PLOD3	98	69.231	ENSCAFG00000016522	PLOD1	97	59.801	Canis_familiaris
ENSG00000106397	PLOD3	98	76.923	ENSCAFG00000008101	PLOD2	94	58.506	Canis_familiaris
ENSG00000106397	PLOD3	98	69.231	ENSCAFG00020009101	PLOD1	97	59.801	Canis_lupus_dingo
ENSG00000106397	PLOD3	98	96.923	ENSCAFG00020013249	PLOD3	100	94.459	Canis_lupus_dingo
ENSG00000106397	PLOD3	98	76.923	ENSCAFG00020011739	PLOD2	99	58.939	Canis_lupus_dingo
ENSG00000106397	PLOD3	97	94.951	ENSCHIG00000015476	PLOD3	98	93.902	Capra_hircus
ENSG00000106397	PLOD3	98	76.923	ENSCHIG00000018266	PLOD2	97	59.716	Capra_hircus
ENSG00000106397	PLOD3	98	67.692	ENSCHIG00000025580	PLOD1	97	60.369	Capra_hircus
ENSG00000106397	PLOD3	98	67.692	ENSTSYG00000035536	PLOD1	100	59.733	Carlito_syrichta
ENSG00000106397	PLOD3	98	76.923	ENSTSYG00000007171	PLOD2	100	59.486	Carlito_syrichta
ENSG00000106397	PLOD3	97	78.125	ENSCAPG00000010686	PLOD2	88	65.939	Cavia_aperea
ENSG00000106397	PLOD3	98	78.462	ENSCPOG00000014514	PLOD2	99	55.289	Cavia_porcellus
ENSG00000106397	PLOD3	98	66.154	ENSCCAG00000024821	PLOD1	97	59.375	Cebus_capucinus
ENSG00000106397	PLOD3	98	76.923	ENSCCAG00000025733	PLOD2	97	58.856	Cebus_capucinus
ENSG00000106397	PLOD3	98	98.462	ENSCCAG00000031443	PLOD3	100	96.361	Cebus_capucinus
ENSG00000106397	PLOD3	100	98.238	ENSCATG00000038394	PLOD3	100	98.238	Cercocebus_atys
ENSG00000106397	PLOD3	98	76.923	ENSCATG00000041420	PLOD2	97	58.264	Cercocebus_atys
ENSG00000106397	PLOD3	98	64.615	ENSCATG00000017580	PLOD1	98	57.610	Cercocebus_atys
ENSG00000106397	PLOD3	98	93.846	ENSCLAG00000006817	PLOD3	97	93.036	Chinchilla_lanigera
ENSG00000106397	PLOD3	98	78.462	ENSCLAG00000008696	PLOD2	97	60.028	Chinchilla_lanigera
ENSG00000106397	PLOD3	98	67.692	ENSCLAG00000013276	PLOD1	97	60.057	Chinchilla_lanigera
ENSG00000106397	PLOD3	98	76.923	ENSCSAG00000011365	PLOD2	95	58.368	Chlorocebus_sabaeus
ENSG00000106397	PLOD3	100	98.238	ENSCSAG00000018025	PLOD3	100	98.238	Chlorocebus_sabaeus
ENSG00000106397	PLOD3	98	76.923	ENSCPBG00000010409	PLOD3	98	72.152	Chrysemys_picta_bellii
ENSG00000106397	PLOD3	98	72.308	ENSCPBG00000021958	PLOD1	96	60.938	Chrysemys_picta_bellii
ENSG00000106397	PLOD3	98	76.923	ENSCANG00000032726	PLOD2	95	59.972	Colobus_angolensis_palliatus
ENSG00000106397	PLOD3	100	98.509	ENSCANG00000042030	PLOD3	100	98.509	Colobus_angolensis_palliatus
ENSG00000106397	PLOD3	98	66.154	ENSCANG00000000277	PLOD1	97	59.233	Colobus_angolensis_palliatus
ENSG00000106397	PLOD3	98	76.923	ENSCGRG00001022906	Plod2	96	59.021	Cricetulus_griseus_chok1gshd
ENSG00000106397	PLOD3	98	95.385	ENSCGRG00001017088	Plod3	100	88.005	Cricetulus_griseus_chok1gshd
ENSG00000106397	PLOD3	98	93.846	ENSCGRG00000009240	Plod3	100	87.874	Cricetulus_griseus_crigri
ENSG00000106397	PLOD3	98	76.923	ENSCGRG00000001261	Plod2	99	59.021	Cricetulus_griseus_crigri
ENSG00000106397	PLOD3	98	73.846	ENSCVAG00000015237	plod3	99	64.771	Cyprinodon_variegatus
ENSG00000106397	PLOD3	98	66.154	ENSCVAG00000020899	plod1a	96	57.386	Cyprinodon_variegatus
ENSG00000106397	PLOD3	98	72.308	ENSDARG00000011821	plod2	96	60.684	Danio_rerio
ENSG00000106397	PLOD3	98	66.154	ENSDARG00000059746	plod1a	96	58.974	Danio_rerio
ENSG00000106397	PLOD3	98	75.385	ENSDARG00000076317	plod3	97	66.056	Danio_rerio
ENSG00000106397	PLOD3	98	76.923	ENSDNOG00000005149	PLOD2	96	56.071	Dasypus_novemcinctus
ENSG00000106397	PLOD3	97	67.188	ENSDNOG00000030750	PLOD1	97	60.085	Dasypus_novemcinctus
ENSG00000106397	PLOD3	98	78.462	ENSDORG00000003217	Plod2	100	59.629	Dipodomys_ordii
ENSG00000106397	PLOD3	98	69.231	ENSDORG00000008737	Plod1	99	57.223	Dipodomys_ordii
ENSG00000106397	PLOD3	98	50.769	FBgn0036147	Plod	96	46.034	Drosophila_melanogaster
ENSG00000106397	PLOD3	98	69.231	ENSEASG00005016643	PLOD1	97	54.495	Equus_asinus_asinus
ENSG00000106397	PLOD3	98	76.923	ENSEASG00005000164	PLOD2	95	60.114	Equus_asinus_asinus
ENSG00000106397	PLOD3	98	96.923	ENSEASG00005016919	PLOD3	100	93.531	Equus_asinus_asinus
ENSG00000106397	PLOD3	98	67.692	ENSECAG00000022842	PLOD1	97	60.085	Equus_caballus
ENSG00000106397	PLOD3	98	76.923	ENSECAG00000009297	PLOD2	95	60.114	Equus_caballus
ENSG00000106397	PLOD3	98	96.923	ENSECAG00000021913	PLOD3	100	93.405	Equus_caballus
ENSG00000106397	PLOD3	89	49.020	ENSEEUG00000015012	PLOD2	85	48.980	Erinaceus_europaeus
ENSG00000106397	PLOD3	98	69.231	ENSFCAG00000000074	PLOD1	97	60.085	Felis_catus
ENSG00000106397	PLOD3	98	76.923	ENSFCAG00000023549	PLOD2	96	59.384	Felis_catus
ENSG00000106397	PLOD3	98	96.923	ENSFCAG00000005798	PLOD3	100	92.973	Felis_catus
ENSG00000106397	PLOD3	98	75.385	ENSFALG00000010022	PLOD1	97	60.197	Ficedula_albicollis
ENSG00000106397	PLOD3	98	76.923	ENSFALG00000007086	PLOD2	93	59.557	Ficedula_albicollis
ENSG00000106397	PLOD3	98	64.615	ENSFDAG00000013861	PLOD1	100	60.284	Fukomys_damarensis
ENSG00000106397	PLOD3	98	95.385	ENSFDAG00000007784	PLOD3	97	92.340	Fukomys_damarensis
ENSG00000106397	PLOD3	98	76.923	ENSFDAG00000011434	PLOD2	100	57.721	Fukomys_damarensis
ENSG00000106397	PLOD3	98	61.538	ENSFHEG00000021014	plod1a	99	56.601	Fundulus_heteroclitus
ENSG00000106397	PLOD3	89	58.246	ENSFHEG00000019833	plod3	79	69.825	Fundulus_heteroclitus
ENSG00000106397	PLOD3	98	63.077	ENSGMOG00000003290	plod1a	99	58.723	Gadus_morhua
ENSG00000106397	PLOD3	98	75.385	ENSGALG00000006783	PLOD2	100	59.091	Gallus_gallus
ENSG00000106397	PLOD3	98	76.923	ENSGALG00000004531	PLOD1	96	60.227	Gallus_gallus
ENSG00000106397	PLOD3	98	73.846	ENSGAFG00000020388	plod3	99	67.033	Gambusia_affinis
ENSG00000106397	PLOD3	98	63.077	ENSGAFG00000014860	plod1a	97	56.583	Gambusia_affinis
ENSG00000106397	PLOD3	98	63.077	ENSGACG00000013243	plod1a	96	56.108	Gasterosteus_aculeatus
ENSG00000106397	PLOD3	98	73.846	ENSGAGG00000016382	PLOD1	97	56.676	Gopherus_agassizii
ENSG00000106397	PLOD3	98	76.923	ENSGGOG00000014284	PLOD2	95	59.829	Gorilla_gorilla
ENSG00000106397	PLOD3	100	100.000	ENSGGOG00000016700	PLOD3	100	99.593	Gorilla_gorilla
ENSG00000106397	PLOD3	98	66.154	ENSGGOG00000013645	PLOD1	97	59.517	Gorilla_gorilla
ENSG00000106397	PLOD3	98	66.154	ENSHBUG00000020042	plod1a	99	52.063	Haplochromis_burtoni
ENSG00000106397	PLOD3	98	73.846	ENSHBUG00000015944	plod2	98	61.722	Haplochromis_burtoni
ENSG00000106397	PLOD3	98	64.615	ENSHGLG00000011999	PLOD1	97	59.233	Heterocephalus_glaber_female
ENSG00000106397	PLOD3	98	95.385	ENSHGLG00000016800	PLOD3	97	91.922	Heterocephalus_glaber_female
ENSG00000106397	PLOD3	98	78.462	ENSHGLG00000019219	PLOD2	95	60.399	Heterocephalus_glaber_female
ENSG00000106397	PLOD3	98	78.462	ENSHGLG00100003295	PLOD2	95	60.399	Heterocephalus_glaber_male
ENSG00000106397	PLOD3	98	95.385	ENSHGLG00100008805	PLOD3	97	91.922	Heterocephalus_glaber_male
ENSG00000106397	PLOD3	98	64.615	ENSHGLG00100012433	PLOD1	97	59.233	Heterocephalus_glaber_male
ENSG00000106397	PLOD3	98	70.769	ENSHCOG00000009023	plod3	92	63.701	Hippocampus_comes
ENSG00000106397	PLOD3	98	70.769	ENSIPUG00000001033	plod2	97	61.072	Ictalurus_punctatus
ENSG00000106397	PLOD3	98	76.923	ENSSTOG00000025550	PLOD2	97	58.996	Ictidomys_tridecemlineatus
ENSG00000106397	PLOD3	98	64.615	ENSSTOG00000009927	PLOD1	96	59.916	Ictidomys_tridecemlineatus
ENSG00000106397	PLOD3	100	94.189	ENSSTOG00000022109	PLOD3	100	94.189	Ictidomys_tridecemlineatus
ENSG00000106397	PLOD3	98	76.923	ENSJJAG00000013305	Plod2	100	57.895	Jaculus_jaculus
ENSG00000106397	PLOD3	98	67.692	ENSJJAG00000013988	Plod1	98	60.449	Jaculus_jaculus
ENSG00000106397	PLOD3	97	93.324	ENSJJAG00000017235	Plod3	97	93.315	Jaculus_jaculus
ENSG00000106397	PLOD3	98	64.615	ENSLBEG00000015540	plod1a	98	57.812	Labrus_bergylta
ENSG00000106397	PLOD3	98	75.385	ENSLOCG00000014098	plod3	96	66.525	Lepisosteus_oculatus
ENSG00000106397	PLOD3	98	73.846	ENSLOCG00000007750	plod2	92	59.890	Lepisosteus_oculatus
ENSG00000106397	PLOD3	98	67.692	ENSLAFG00000000373	PLOD1	97	59.659	Loxodonta_africana
ENSG00000106397	PLOD3	98	75.385	ENSLAFG00000001931	PLOD2	100	60.284	Loxodonta_africana
ENSG00000106397	PLOD3	98	95.385	ENSLAFG00000021710	PLOD3	100	92.173	Loxodonta_africana
ENSG00000106397	PLOD3	98	100.000	ENSMFAG00000033241	PLOD3	100	97.967	Macaca_fascicularis
ENSG00000106397	PLOD3	98	64.615	ENSMFAG00000037610	PLOD1	98	59.459	Macaca_fascicularis
ENSG00000106397	PLOD3	98	76.923	ENSMFAG00000038516	PLOD2	98	58.009	Macaca_fascicularis
ENSG00000106397	PLOD3	98	76.923	ENSMMUG00000011577	PLOD2	100	58.097	Macaca_mulatta
ENSG00000106397	PLOD3	98	64.615	ENSMMUG00000032249	PLOD1	83	59.375	Macaca_mulatta
ENSG00000106397	PLOD3	98	100.000	ENSMMUG00000006949	PLOD3	100	97.967	Macaca_mulatta
ENSG00000106397	PLOD3	100	98.103	ENSMNEG00000036923	PLOD3	100	98.103	Macaca_nemestrina
ENSG00000106397	PLOD3	98	76.923	ENSMNEG00000029275	PLOD2	98	57.864	Macaca_nemestrina
ENSG00000106397	PLOD3	98	64.615	ENSMNEG00000038691	PLOD1	97	59.375	Macaca_nemestrina
ENSG00000106397	PLOD3	100	98.238	ENSMLEG00000036735	PLOD3	100	98.238	Mandrillus_leucophaeus
ENSG00000106397	PLOD3	98	76.923	ENSMLEG00000032487	PLOD2	95	59.972	Mandrillus_leucophaeus
ENSG00000106397	PLOD3	97	64.062	ENSMAMG00000014686	plod1a	96	56.860	Mastacembelus_armatus
ENSG00000106397	PLOD3	98	73.846	ENSMZEG00005017645	plod2	97	61.538	Maylandia_zebra
ENSG00000106397	PLOD3	99	47.302	ENSMZEG00005019823	plod2	100	54.076	Maylandia_zebra
ENSG00000106397	PLOD3	98	66.154	ENSMZEG00005006985	plod1a	96	56.960	Maylandia_zebra
ENSG00000106397	PLOD3	98	76.923	ENSMGAG00000006085	PLOD1	96	60.369	Meleagris_gallopavo
ENSG00000106397	PLOD3	98	75.385	ENSMGAG00000006583	PLOD2	96	59.972	Meleagris_gallopavo
ENSG00000106397	PLOD3	71	91.011	ENSMAUG00000014281	Plod3	100	93.689	Mesocricetus_auratus
ENSG00000106397	PLOD3	98	76.923	ENSMAUG00000003215	Plod2	95	59.402	Mesocricetus_auratus
ENSG00000106397	PLOD3	98	95.385	ENSMICG00000033937	-	97	90.403	Microcebus_murinus
ENSG00000106397	PLOD3	98	76.923	ENSMICG00000049252	PLOD2	97	59.414	Microcebus_murinus
ENSG00000106397	PLOD3	89	75.789	ENSMICG00000005429	-	91	92.982	Microcebus_murinus
ENSG00000106397	PLOD3	98	67.692	ENSMICG00000002720	PLOD1	97	59.801	Microcebus_murinus
ENSG00000106397	PLOD3	98	76.923	ENSMOCG00000014848	Plod2	96	59.402	Microtus_ochrogaster
ENSG00000106397	PLOD3	98	95.385	ENSMOCG00000001131	Plod3	100	93.252	Microtus_ochrogaster
ENSG00000106397	PLOD3	98	67.692	ENSMOCG00000012299	Plod1	97	60.085	Microtus_ochrogaster
ENSG00000106397	PLOD3	98	64.615	ENSMMOG00000013171	plod1a	99	56.657	Mola_mola
ENSG00000106397	PLOD3	98	75.385	ENSMMOG00000011128	plod3	94	62.953	Mola_mola
ENSG00000106397	PLOD3	98	92.308	ENSMODG00000005017	PLOD3	99	85.896	Monodelphis_domestica
ENSG00000106397	PLOD3	97	65.625	ENSMODG00000010880	PLOD1	96	60.227	Monodelphis_domestica
ENSG00000106397	PLOD3	98	78.462	ENSMODG00000021246	PLOD2	97	61.560	Monodelphis_domestica
ENSG00000106397	PLOD3	97	65.625	ENSMALG00000016161	plod1a	99	57.709	Monopterus_albus
ENSG00000106397	PLOD3	98	66.154	MGP_CAROLIEiJ_G0026786	Plod1	97	60.227	Mus_caroli
ENSG00000106397	PLOD3	98	66.154	ENSMUSG00000019055	Plod1	97	59.943	Mus_musculus
ENSG00000106397	PLOD3	98	75.385	ENSMUSG00000032374	Plod2	96	59.803	Mus_musculus
ENSG00000106397	PLOD3	100	91.228	ENSMUSG00000004846	Plod3	100	91.228	Mus_musculus
ENSG00000106397	PLOD3	98	76.923	MGP_PahariEiJ_G0015394	Plod2	95	60.399	Mus_pahari
ENSG00000106397	PLOD3	98	93.846	MGP_PahariEiJ_G0024447	Plod3	100	91.375	Mus_pahari
ENSG00000106397	PLOD3	98	66.154	MGP_PahariEiJ_G0029134	Plod1	97	59.801	Mus_pahari
ENSG00000106397	PLOD3	100	91.363	MGP_SPRETEiJ_G0028866	Plod3	100	91.363	Mus_spretus
ENSG00000106397	PLOD3	98	66.154	MGP_SPRETEiJ_G0027779	Plod1	97	59.943	Mus_spretus
ENSG00000106397	PLOD3	98	76.923	MGP_SPRETEiJ_G0033668	Plod2	96	59.803	Mus_spretus
ENSG00000106397	PLOD3	98	76.923	ENSMPUG00000011826	PLOD2	96	58.127	Mustela_putorius_furo
ENSG00000106397	PLOD3	98	98.462	ENSMPUG00000015891	PLOD3	100	84.636	Mustela_putorius_furo
ENSG00000106397	PLOD3	98	69.231	ENSMPUG00000016393	PLOD1	92	59.718	Mustela_putorius_furo
ENSG00000106397	PLOD3	98	69.231	ENSMLUG00000007292	PLOD1	94	59.943	Myotis_lucifugus
ENSG00000106397	PLOD3	99	51.051	ENSMLUG00000023471	-	100	60.172	Myotis_lucifugus
ENSG00000106397	PLOD3	98	78.462	ENSNGAG00000000687	Plod2	100	58.704	Nannospalax_galili
ENSG00000106397	PLOD3	98	67.692	ENSNGAG00000008701	-	99	65.385	Nannospalax_galili
ENSG00000106397	PLOD3	98	93.846	ENSNGAG00000018568	Plod3	100	90.786	Nannospalax_galili
ENSG00000106397	PLOD3	98	73.846	ENSNBRG00000017408	plod2	99	61.898	Neolamprologus_brichardi
ENSG00000106397	PLOD3	98	66.154	ENSNBRG00000005025	plod1a	96	57.102	Neolamprologus_brichardi
ENSG00000106397	PLOD3	100	98.667	ENSNLEG00000008234	PLOD3	100	94.118	Nomascus_leucogenys
ENSG00000106397	PLOD3	98	76.923	ENSNLEG00000005034	PLOD2	95	59.687	Nomascus_leucogenys
ENSG00000106397	PLOD3	98	76.923	ENSMEUG00000012969	PLOD2	88	61.088	Notamacropus_eugenii
ENSG00000106397	PLOD3	98	66.154	ENSMEUG00000008093	PLOD1	99	59.972	Notamacropus_eugenii
ENSG00000106397	PLOD3	98	93.846	ENSMEUG00000015654	PLOD3	85	92.473	Notamacropus_eugenii
ENSG00000106397	PLOD3	98	64.615	ENSOPRG00000006783	PLOD1	99	59.544	Ochotona_princeps
ENSG00000106397	PLOD3	94	72.581	ENSOPRG00000006945	PLOD2	91	40.480	Ochotona_princeps
ENSG00000106397	PLOD3	98	78.462	ENSODEG00000009443	PLOD2	97	59.610	Octodon_degus
ENSG00000106397	PLOD3	98	95.385	ENSODEG00000016528	PLOD3	96	92.201	Octodon_degus
ENSG00000106397	PLOD3	98	67.692	ENSODEG00000013340	PLOD1	97	56.901	Octodon_degus
ENSG00000106397	PLOD3	98	66.154	ENSONIG00000017978	-	96	56.818	Oreochromis_niloticus
ENSG00000106397	PLOD3	98	73.846	ENSONIG00000005883	plod2	98	59.784	Oreochromis_niloticus
ENSG00000106397	PLOD3	98	69.231	ENSOANG00000004585	-	97	59.662	Ornithorhynchus_anatinus
ENSG00000106397	PLOD3	98	80.000	ENSOCUG00000001461	PLOD2	97	57.375	Oryctolagus_cuniculus
ENSG00000106397	PLOD3	82	90.972	ENSOCUG00000021812	PLOD3	90	93.772	Oryctolagus_cuniculus
ENSG00000106397	PLOD3	98	66.154	ENSOCUG00000007960	PLOD1	92	59.155	Oryctolagus_cuniculus
ENSG00000106397	PLOD3	98	63.077	ENSORLG00000018904	plod1a	96	55.304	Oryzias_latipes
ENSG00000106397	PLOD3	98	75.385	ENSORLG00000029631	plod3	100	69.505	Oryzias_latipes
ENSG00000106397	PLOD3	98	75.385	ENSORLG00015001924	plod3	98	67.222	Oryzias_latipes_hsok
ENSG00000106397	PLOD3	98	73.846	ENSOMEG00000006893	plod3	97	65.590	Oryzias_melastigma
ENSG00000106397	PLOD3	98	64.615	ENSOMEG00000022732	plod1a	98	56.727	Oryzias_melastigma
ENSG00000106397	PLOD3	95	54.772	ENSOGAG00000009905	PLOD2	100	54.772	Otolemur_garnettii
ENSG00000106397	PLOD3	99	56.731	ENSOGAG00000005351	PLOD1	98	57.203	Otolemur_garnettii
ENSG00000106397	PLOD3	98	98.462	ENSOGAG00000031724	PLOD3	100	92.742	Otolemur_garnettii
ENSG00000106397	PLOD3	98	67.692	ENSOARG00000017960	PLOD1	100	60.369	Ovis_aries
ENSG00000106397	PLOD3	98	76.923	ENSOARG00000005685	PLOD2	86	58.230	Ovis_aries
ENSG00000106397	PLOD3	98	93.846	ENSOARG00000015057	PLOD3	98	92.453	Ovis_aries
ENSG00000106397	PLOD3	100	99.593	ENSPPAG00000038349	PLOD3	100	99.593	Pan_paniscus
ENSG00000106397	PLOD3	98	66.154	ENSPPAG00000034724	PLOD1	97	59.517	Pan_paniscus
ENSG00000106397	PLOD3	98	76.923	ENSPPAG00000039540	PLOD2	95	59.829	Pan_paniscus
ENSG00000106397	PLOD3	98	69.231	ENSPPRG00000007588	PLOD1	97	59.659	Panthera_pardus
ENSG00000106397	PLOD3	98	76.923	ENSPPRG00000012277	PLOD2	96	59.524	Panthera_pardus
ENSG00000106397	PLOD3	98	76.923	ENSPTIG00000018891	PLOD2	100	58.097	Panthera_tigris_altaica
ENSG00000106397	PLOD3	98	69.231	ENSPTIG00000020156	PLOD1	96	60.028	Panthera_tigris_altaica
ENSG00000106397	PLOD3	100	99.593	ENSPTRG00000019524	PLOD3	100	99.593	Pan_troglodytes
ENSG00000106397	PLOD3	100	99.593	ENSPTRG00000051360	-	100	99.593	Pan_troglodytes
ENSG00000106397	PLOD3	98	76.923	ENSPTRG00000015494	PLOD2	95	59.829	Pan_troglodytes
ENSG00000106397	PLOD3	98	66.154	ENSPTRG00000000158	PLOD1	97	59.517	Pan_troglodytes
ENSG00000106397	PLOD3	100	98.238	ENSPANG00000021830	PLOD3	100	98.238	Papio_anubis
ENSG00000106397	PLOD3	98	64.615	ENSPANG00000009766	PLOD1	97	57.670	Papio_anubis
ENSG00000106397	PLOD3	98	76.923	ENSPANG00000020900	PLOD2	98	58.009	Papio_anubis
ENSG00000106397	PLOD3	98	72.308	ENSPKIG00000009566	plod2	100	61.054	Paramormyrops_kingsleyae
ENSG00000106397	PLOD3	98	64.615	ENSPKIG00000013959	plod1a	97	58.087	Paramormyrops_kingsleyae
ENSG00000106397	PLOD3	98	70.769	ENSPSIG00000011107	PLOD1	96	60.369	Pelodiscus_sinensis
ENSG00000106397	PLOD3	98	95.385	ENSPEMG00000000016	Plod3	100	91.903	Peromyscus_maniculatus_bairdii
ENSG00000106397	PLOD3	98	67.692	ENSPEMG00000000181	Plod1	97	60.369	Peromyscus_maniculatus_bairdii
ENSG00000106397	PLOD3	98	73.846	ENSPEMG00000023460	Plod2	100	57.341	Peromyscus_maniculatus_bairdii
ENSG00000106397	PLOD3	97	70.312	ENSPMAG00000003203	-	96	61.932	Petromyzon_marinus
ENSG00000106397	PLOD3	97	75.000	ENSPMAG00000008153	plod2	97	67.500	Petromyzon_marinus
ENSG00000106397	PLOD3	98	93.846	ENSPCIG00000019207	PLOD3	93	86.338	Phascolarctos_cinereus
ENSG00000106397	PLOD3	98	78.462	ENSPCIG00000018522	PLOD2	97	61.281	Phascolarctos_cinereus
ENSG00000106397	PLOD3	97	64.062	ENSPCIG00000030260	PLOD1	97	59.551	Phascolarctos_cinereus
ENSG00000106397	PLOD3	98	63.077	ENSPFOG00000017414	plod1a	96	57.850	Poecilia_formosa
ENSG00000106397	PLOD3	98	63.077	ENSPLAG00000018953	plod1a	99	57.511	Poecilia_latipinna
ENSG00000106397	PLOD3	98	76.923	ENSPLAG00000004494	plod3	97	64.124	Poecilia_latipinna
ENSG00000106397	PLOD3	98	63.077	ENSPMEG00000021855	plod1a	96	57.850	Poecilia_mexicana
ENSG00000106397	PLOD3	98	76.923	ENSPMEG00000001542	plod3	97	64.124	Poecilia_mexicana
ENSG00000106397	PLOD3	98	63.077	ENSPREG00000008836	plod1a	95	57.041	Poecilia_reticulata
ENSG00000106397	PLOD3	98	66.154	ENSPPYG00000001874	PLOD1	97	59.659	Pongo_abelii
ENSG00000106397	PLOD3	98	76.923	ENSPPYG00000029800	-	100	61.658	Pongo_abelii
ENSG00000106397	PLOD3	100	100.000	ENSPPYG00000017444	PLOD3	100	99.322	Pongo_abelii
ENSG00000106397	PLOD3	98	67.692	ENSPCOG00000013522	PLOD1	97	59.943	Propithecus_coquereli
ENSG00000106397	PLOD3	98	98.462	ENSPCOG00000015483	PLOD3	100	93.657	Propithecus_coquereli
ENSG00000106397	PLOD3	98	95.385	ENSPVAG00000001241	PLOD3	100	88.160	Pteropus_vampyrus
ENSG00000106397	PLOD3	98	66.154	ENSPNYG00000000578	plod1a	99	53.814	Pundamilia_nyererei
ENSG00000106397	PLOD3	98	73.846	ENSPNYG00000006024	plod2	100	61.718	Pundamilia_nyererei
ENSG00000106397	PLOD3	98	64.615	ENSPNAG00000004781	plod1a	97	57.644	Pygocentrus_nattereri
ENSG00000106397	PLOD3	98	72.308	ENSPNAG00000021984	plod3	97	65.674	Pygocentrus_nattereri
ENSG00000106397	PLOD3	98	67.692	ENSRNOG00000007763	Plod1	97	60.085	Rattus_norvegicus
ENSG00000106397	PLOD3	98	76.923	ENSRNOG00000030183	Plod2	95	59.829	Rattus_norvegicus
ENSG00000106397	PLOD3	99	66.540	ENSRBIG00000035926	PLOD1	96	55.256	Rhinopithecus_bieti
ENSG00000106397	PLOD3	98	76.923	ENSRBIG00000042963	PLOD2	100	57.721	Rhinopithecus_bieti
ENSG00000106397	PLOD3	98	76.923	ENSRROG00000031649	PLOD2	95	58.368	Rhinopithecus_roxellana
ENSG00000106397	PLOD3	100	98.374	ENSRROG00000038379	PLOD3	100	98.374	Rhinopithecus_roxellana
ENSG00000106397	PLOD3	98	98.462	ENSSBOG00000020136	PLOD3	100	96.070	Saimiri_boliviensis_boliviensis
ENSG00000106397	PLOD3	99	52.866	ENSSBOG00000021276	PLOD1	98	51.549	Saimiri_boliviensis_boliviensis
ENSG00000106397	PLOD3	98	76.923	ENSSBOG00000030460	PLOD2	100	58.097	Saimiri_boliviensis_boliviensis
ENSG00000106397	PLOD3	97	64.062	ENSSHAG00000007375	PLOD1	95	60.169	Sarcophilus_harrisii
ENSG00000106397	PLOD3	98	93.846	ENSSHAG00000001739	PLOD3	95	85.437	Sarcophilus_harrisii
ENSG00000106397	PLOD3	98	78.462	ENSSHAG00000017470	PLOD2	98	60.166	Sarcophilus_harrisii
ENSG00000106397	PLOD3	98	78.462	ENSSFOG00015017276	plod3	96	67.327	Scleropages_formosus
ENSG00000106397	PLOD3	98	76.923	ENSSFOG00015022468	plod3	96	65.816	Scleropages_formosus
ENSG00000106397	PLOD3	98	72.308	ENSSFOG00015014512	plod2	96	61.259	Scleropages_formosus
ENSG00000106397	PLOD3	98	72.308	ENSSFOG00015010374	plod1a	99	58.725	Scleropages_formosus
ENSG00000106397	PLOD3	98	66.154	ENSSMAG00000011129	plod1a	97	56.056	Scophthalmus_maximus
ENSG00000106397	PLOD3	98	73.846	ENSSDUG00000002200	plod3	97	66.525	Seriola_dumerili
ENSG00000106397	PLOD3	98	64.615	ENSSDUG00000002187	plod1a	96	57.143	Seriola_dumerili
ENSG00000106397	PLOD3	98	64.615	ENSSLDG00000016960	plod1a	90	55.540	Seriola_lalandi_dorsalis
ENSG00000106397	PLOD3	90	64.615	ENSSLDG00000007569	plod3	92	59.722	Seriola_lalandi_dorsalis
ENSG00000106397	PLOD3	89	49.346	ENSSARG00000003690	PLOD2	79	55.556	Sorex_araneus
ENSG00000106397	PLOD3	98	95.385	ENSSSCG00000028879	PLOD3	99	93.902	Sus_scrofa
ENSG00000106397	PLOD3	98	67.692	ENSSSCG00000003433	PLOD1	97	60.085	Sus_scrofa
ENSG00000106397	PLOD3	98	76.923	ENSSSCG00000011689	PLOD2	100	58.807	Sus_scrofa
ENSG00000106397	PLOD3	98	75.385	ENSTGUG00000008767	PLOD2	99	60.795	Taeniopygia_guttata
ENSG00000106397	PLOD3	98	76.923	ENSTGUG00000002406	-	97	60.338	Taeniopygia_guttata
ENSG00000106397	PLOD3	98	67.692	ENSTRUG00000008466	plod1	98	55.050	Takifugu_rubripes
ENSG00000106397	PLOD3	98	76.923	ENSTBEG00000015790	PLOD2	92	65.500	Tupaia_belangeri
ENSG00000106397	PLOD3	98	95.385	ENSTBEG00000014615	PLOD3	100	94.716	Tupaia_belangeri
ENSG00000106397	PLOD3	98	95.385	ENSTTRG00000004781	PLOD3	99	93.360	Tursiops_truncatus
ENSG00000106397	PLOD3	98	67.692	ENSTTRG00000003503	PLOD1	97	59.659	Tursiops_truncatus
ENSG00000106397	PLOD3	98	69.231	ENSUAMG00000010387	PLOD1	97	60.085	Ursus_americanus
ENSG00000106397	PLOD3	98	96.923	ENSUAMG00000013690	PLOD3	100	90.000	Ursus_americanus
ENSG00000106397	PLOD3	98	76.923	ENSUAMG00000020858	PLOD2	98	57.163	Ursus_americanus
ENSG00000106397	PLOD3	98	69.231	ENSUMAG00000022265	PLOD1	99	59.110	Ursus_maritimus
ENSG00000106397	PLOD3	98	76.923	ENSUMAG00000012593	PLOD2	100	58.665	Ursus_maritimus
ENSG00000106397	PLOD3	98	83.077	ENSVPAG00000001811	-	69	77.495	Vicugna_pacos
ENSG00000106397	PLOD3	98	96.923	ENSVVUG00000023620	PLOD3	100	94.452	Vulpes_vulpes
ENSG00000106397	PLOD3	98	76.923	ENSVVUG00000008510	PLOD2	99	60.284	Vulpes_vulpes
ENSG00000106397	PLOD3	98	69.231	ENSVVUG00000028568	PLOD1	96	59.406	Vulpes_vulpes
ENSG00000106397	PLOD3	98	63.077	ENSXCOG00000002023	plod1a	98	56.061	Xiphophorus_couchianus
ENSG00000106397	PLOD3	98	75.385	ENSXMAG00000002047	plod3	98	67.967	Xiphophorus_maculatus
ENSG00000106397	PLOD3	98	63.077	ENSXMAG00000004495	plod1a	97	56.162	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0001701	in utero embryonic development	-	IEA	Process
GO:0001886	endothelial cell morphogenesis	-	IEA	Process
GO:0005506	iron ion binding	-	IEA	Function
GO:0005515	protein binding	16189514.25416956.25910212.26028330.	IPI	Function
GO:0005615	extracellular space	-	ISS	Component
GO:0005783	endoplasmic reticulum	10934207.	IDA	Component
GO:0005783	endoplasmic reticulum	9724729.	TAS	Component
GO:0005788	endoplasmic reticulum lumen	-	IEA	Component
GO:0005789	endoplasmic reticulum membrane	-	TAS	Component
GO:0005791	rough endoplasmic reticulum	-	IEA	Component
GO:0005794	Golgi apparatus	10934207.27435297.	IDA	Component
GO:0005802	trans-Golgi network	-	IEA	Component
GO:0006493	protein O-linked glycosylation	10934207.	IMP	Process
GO:0008104	protein localization	-	IEA	Process
GO:0008475	procollagen-lysine 5-dioxygenase activity	21873635.	IBA	Function
GO:0008475	procollagen-lysine 5-dioxygenase activity	9582318.9724729.	IDA	Function
GO:0008475	procollagen-lysine 5-dioxygenase activity	10934207.18298658.	IMP	Function
GO:0017185	peptidyl-lysine hydroxylation	21873635.	IBA	Process
GO:0017185	peptidyl-lysine hydroxylation	9582318.9724729.	IDA	Process
GO:0017185	peptidyl-lysine hydroxylation	10934207.18298658.	IMP	Process
GO:0021915	neural tube development	-	IEA	Process
GO:0030199	collagen fibril organization	21873635.	IBA	Process
GO:0031418	L-ascorbic acid binding	-	IEA	Function
GO:0032870	cellular response to hormone stimulus	-	IEA	Process
GO:0032963	collagen metabolic process	21873635.	IBA	Process
GO:0033823	procollagen glucosyltransferase activity	10934207.18298658.	IMP	Function
GO:0042311	vasodilation	-	IEA	Process
GO:0046947	hydroxylysine biosynthetic process	21873635.	IBA	Process
GO:0046947	hydroxylysine biosynthetic process	9582318.9724729.	IDA	Process
GO:0046947	hydroxylysine biosynthetic process	10934207.18298658.	IMP	Process
GO:0048730	epidermis morphogenesis	-	IEA	Process
GO:0050211	procollagen galactosyltransferase activity	18298658.	IMP	Function
GO:0050211	procollagen galactosyltransferase activity	-	TAS	Function
GO:0055114	oxidation-reduction process	-	IEA	Process
GO:0060425	lung morphogenesis	-	IEA	Process
GO:0062023	collagen-containing extracellular matrix	-	IEA	Component
GO:0070062	extracellular exosome	19056867.19199708.	HDA	Component
GO:0070831	basement membrane assembly	-	IEA	Process

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
ACC	chr7	101212263	Missense_Mutation	novel	D373Y	0.36
ACC	chr7	101212264	Silent	novel	R372R	0.35
BLCA	chr7	101206401	Silent	novel	V699V	0.54
BLCA	chr7	101212869	Missense_Mutation	novel	Q284H	0.6
BLCA	chr7	101212878	Silent	NA	F281F	0.34
BLCA	chr7	101215911	Silent	novel	L204L	0.54
BLCA	chr7	101216754	Nonsense_Mutation	novel	E48*	0.39
BLCA	chr7	101216748	Nonsense_Mutation	novel	E50*	0.3
BLCA	chr7	101210624	Missense_Mutation	novel	D470N	0.29
BLCA	chr7	101215911	Silent	novel	L204L	0.24
BRCA	chr7	101212845	Frame_Shift_Del	NA	*Q293Sfs65**	0.19
BRCA	chr7	101212882	Missense_Mutation	NA	G280A	0.23
BRCA	chr7	101212298	Missense_Mutation	novel	G361V	0.35
BRCA	chr7	101216473	Missense_Mutation	novel	W92L	0.08
BRCA	chr7	101217948	5'Flank	NA		0.63
BRCA	chr7	101210568	Silent	NA	D488D	0.23
BRCA	chr7	101216731	Silent	NA	F55F	0.47
BRCA	chr7	101206234	3'UTR	novel		0.16
CESC	chr7	101210539	Missense_Mutation	rs777238858	R498Q	0.15
CESC	chr7	101206220	3'UTR	rs182092925		0.22
CESC	chr7	101208946	Silent	rs376877769	D565D	0.41
CESC	chr7	101206268	3'UTR	novel		0.38
COAD	chr7	101212530	Splice_Region	rs763712959	N335N	0.23
COAD	chr7	101212917	Silent	rs202155755	Y268Y	0.44
COAD	chr7	101217259	Missense_Mutation	novel	P6S	0.39
COAD	chr7	101213162	Missense_Mutation	rs141948483	R241Q	0.29
COAD	chr7	101215980	Silent	novel	R181R	0.3
COAD	chr7	101215956	Silent	rs201040631	D189D	0.31
COAD	chr7	101210092	Splice_Site	NA	X561_splice	0.33
COAD	chr7	101211685	Missense_Mutation	NA	G422S	0.3
COAD	chr7	101206854	Silent	rs117761436	P662P	0.23
COAD	chr7	101216286	Missense_Mutation	NA	K127Q	0.3
COAD	chr7	101217223	Silent	NA	L18L	0.5
COAD	chr7	101212922	Missense_Mutation	novel	N267D	0.13
COAD	chr7	101211867	Missense_Mutation	novel	R404L	0.43
COAD	chr7	101210138	Silent	NA	H546H	0.26
ESCA	chr7	101211905	Silent	novel	L391L	0.71
ESCA	chr7	101211860	Silent	rs752044431	L406L	0.22
ESCA	chr7	101206314	Silent	novel	T728T	0.38
ESCA	chr7	101215981	Missense_Mutation	rs764596991	R181H	0.14
ESCA	chr7	101218356	5'Flank	novel		0.43
GBM	chr7	101210405	Missense_Mutation	novel	R514G	0.04
GBM	chr7	101216713	Missense_Mutation	novel	F61L	0.25
HNSC	chr7	101206409	Missense_Mutation	rs199647243	D697N	0.27	2OG-FeII_Oxy
HNSC	chr7	101212272	Missense_Mutation	rs772269466	E370K	0.12
HNSC	chr7	101216242	Missense_Mutation	novel	E141D	0.15
HNSC	chr7	101212839	Splice_Region	novel		0.32
HNSC	chr7	101216716	Silent	novel	E60E	0.24
HNSC	chr7	101215982	Missense_Mutation	rs761949569	R181C	0.32
KIRC	chr7	101213117	Missense_Mutation	NA	G256D	0.21
KIRC	chr7	101212562	Missense_Mutation	novel	P325S	0.07
KIRC	chr7	101216435	Missense_Mutation	NA	D105Y	0.2
KIRC	chr7	101216778	Missense_Mutation	NA	L40M	0.53
KIRC	chr7	101216779	Silent	NA	L39L	0.53
KIRP	chr7	101211865	Missense_Mutation	novel	I405V	0.51
KIRP	chr7	101217278	5'UTR	novel		0.41
LGG	chr7	101216481	Missense_Mutation	novel	K89N	0.25
LIHC	chr7	101212845	Frame_Shift_Del	NA	*Q293Sfs65**	0.37
LIHC	chr7	101211662	Missense_Mutation	novel	W429C	0.61
LUAD	chr7	101210564	Missense_Mutation	novel	D490H	0.09
LUAD	chr7	101210565	Silent	novel	P489P	0.09
LUAD	chr7	101216541	Silent	NA	L69L	0.19
LUAD	chr7	101216303	Missense_Mutation	NA	S121I	0.3
LUAD	chr7	101206326	Silent	novel	T724T	0.13
LUAD	chr7	101207603	Missense_Mutation	rs755547790	S637I	0.13
LUAD	chr7	101207604	Missense_Mutation	novel	S637G	0.13
LUAD	chr7	101216785	Splice_Region	novel	E37E	0.29
LUAD	chr7	101206214	3'UTR	novel		0.1
LUAD	chr7	101210566	Missense_Mutation	rs145508748	P489L	0.1
LUAD	chr7	101212938	Missense_Mutation	NA	Q261H	0.16
LUAD	chr7	101211868	Missense_Mutation	novel	R404S	0.12
LUAD	chr7	101212267	Silent	novel	A371A	0.22
LUAD	chr7	101216272	Missense_Mutation	novel	Q131H	0.53
LUAD	chr7	101216012	Missense_Mutation	novel	G171C	0.38
LUAD	chr7	101212649	Missense_Mutation	novel	P296T	0.3
LUAD	chr7	101207692	Silent	NA	V607V	0.15
LUAD	chr7	101213131	Silent	novel	V251V	0.18
LUSC	chr7	101216519	Missense_Mutation	novel	G77R	0.25
LUSC	chr7	101206237	3'UTR	novel		0.38
LUSC	chr7	101215985	Missense_Mutation	novel	V180L	0.19
LUSC	chr7	101208950	Missense_Mutation	rs749637576	P564L	0.27
LUSC	chr7	101211685	Missense_Mutation	novel	G422C	0.33
LUSC	chr7	101208897	Missense_Mutation	novel	A582S	0.27
LUSC	chr7	101206208	3'UTR	novel		0.23
LUSC	chr7	101210403	Silent	novel	R514R	0.21
LUSC	chr7	101208921	Nonsense_Mutation	novel	E574*	0.14
LUSC	chr7	101207661	Missense_Mutation	novel	G618W	0.39
LUSC	chr7	101212539	Silent	NA	L332L	0.51
LUSC	chr7	101212656	Splice_Site	NA	X294_splice	0.11
LUSC	chr7	101212869	Missense_Mutation	novel	Q284H	0.38
LUSC	chr7	101216251	Silent	novel	F138F	0.21
LUSC	chr7	101216322	Missense_Mutation	novel	D115H	0.09
LUSC	chr7	101211706	Missense_Mutation	rs144508814	A415S	0.43
LUSC	chr7	101208894	Missense_Mutation	NA	E583Q	0.1
LUSC	chr7	101206213	3'UTR	novel		0.4
MESO	chr7	101206887	Missense_Mutation	novel	N651K	0.17
OV	chr7	101206351	Missense_Mutation	novel	T716N	0.24	2OG-FeII_Oxy
OV	chr7	101216474	Missense_Mutation	novel	W92R	0.07
OV	chr7	101206017	3'UTR	novel		0.37
OV	chr7	101212335	Nonsense_Mutation	rs777497883	Q349*	0.29
PAAD	chr7	101212844	Frame_Shift_Ins	novel	*Q293Gfs66**	0.06
PAAD	chr7	101216227	Silent	novel	P146P	0.21
PRAD	chr7	101216455	Missense_Mutation	novel	E98G	0.2
PRAD	chr7	101215922	Missense_Mutation	novel	D201N	0.38
READ	chr7	101208884	Missense_Mutation	novel	H586L	0.09
READ	chr7	101215095	Missense_Mutation	novel	A225T	0.08
SARC	chr7	101211655	Frame_Shift_Del	novel	L432*	0.44
SKCM	chr7	101212609	Missense_Mutation	rs377166799	P309L	0.25
SKCM	chr7	101212610	Missense_Mutation	novel	P309S	0.24
SKCM	chr7	101208944	Missense_Mutation	novel	V566G	0.52
SKCM	chr7	101212651	Missense_Mutation	novel	P295L	0.29
SKCM	chr7	101216251	Silent	novel	F138F	0.21
SKCM	chr7	101212564	Missense_Mutation	NA	P324L	0.93
SKCM	chr7	101206419	Silent	novel	F693F	0.36
SKCM	chr7	101208862	Silent	rs775700406	G593G	0.21
SKCM	chr7	101212608	Silent	rs753031028	P309P	0.35
SKCM	chr7	101213115	Missense_Mutation	NA	P257S	0.19
SKCM	chr7	101210343	Silent	rs768164152	F534F	0.58
SKCM	chr7	101206296	Silent	NA	S734S	0.29
SKCM	chr7	101212336	Silent	rs371771865	P348P	0.11
SKCM	chr7	101212256	Missense_Mutation	rs376124107	A375V	0.31
SKCM	chr7	101207677	Silent	novel	I612I	0.44
SKCM	chr7	101213114	Missense_Mutation	NA	P257L	0.2
STAD	chr7	101210405	Missense_Mutation	rs746896780	R514W	0.5
STAD	chr7	101210405	Missense_Mutation	rs746896780	R514W	0.1
STAD	chr7	101212646	Frame_Shift_Del	rs780620804	*R297Gfs61**	0.56
STAD	chr7	101210669	Missense_Mutation	NA	V455M	0.28
STAD	chr7	101212646	Frame_Shift_Del	rs780620804	*R297Gfs61**	0.25
STAD	chr7	101216242	Silent	NA	E141E	0.22
STAD	chr7	101206312	Missense_Mutation	NA	R729H	0.42	2OG-FeII_Oxy
STAD	chr7	101212273	Silent	rs193247871	G369G	0.47
STAD	chr7	101216188	Silent	rs201433094	T159T	0.14
STAD	chr7	101215974	Nonsense_Mutation	NA	W183*	0.12
STAD	chr7	101212646	Frame_Shift_Del	rs780620804	*R297Gfs61**	0.36
STAD	chr7	101206340	Missense_Mutation	NA	E720K	0.1	2OG-FeII_Oxy
STAD	chr7	101212326	Missense_Mutation	novel	D352Y	0.07
STAD	chr7	101212845	Frame_Shift_Del	NA	*Q293Sfs65**	0.24
STAD	chr7	101212645	Frame_Shift_Ins	rs770446713	*R297Pfs44**	0.28
STAD	chr7	101216189	Missense_Mutation	rs763102265	T159M	0.2
STAD	chr7	101210615	Missense_Mutation	rs770056635	R473W	0.3
STAD	chr7	101212646	Frame_Shift_Del	rs780620804	*R297Gfs61**	0.26
STAD	chr7	101216501	Missense_Mutation	NA	T83A	0.05
STAD	chr7	101211929	Silent	rs767540894	P383P	0.36
UCEC	chr7	101206398	Silent	NA	I700I	0.19
UCEC	chr7	101210553	Silent	NA	F493F	0.3
UCEC	chr7	101213181	Missense_Mutation	rs146134980	R235W	0.41
UCEC	chr7	101217959	5'Flank	NA		0.41
UCEC	chr7	101215981	Missense_Mutation	rs764596991	R181H	0.38
UCEC	chr7	101206252	3'UTR	rs200847748		0.3
UCEC	chr7	101206879	Missense_Mutation	novel	V654A	0.25	2OG-FeII_Oxy
UCEC	chr7	101211898	Missense_Mutation	rs771549876	D394N	0.35
UCEC	chr7	101211932	Silent	novel	D382D	0.33
UCEC	chr7	101207662	Silent	novel	V617V	0.4
UCEC	chr7	101210136	Missense_Mutation	novel	E547V	0.55
UCEC	chr7	101210556	Silent	rs11546150	A492A	0.37
UCEC	chr7	101217259	Missense_Mutation	novel	P6T	0.54
UCEC	chr7	101206359	Silent	novel	G713G	0.44
UCEC	chr7	101212631	Missense_Mutation	rs181326069	V302M	0.4
UCEC	chr7	101212633	Missense_Mutation	novel	A301V	0.43
UCEC	chr7	101216447	Missense_Mutation	rs780846219	A101T	0.32
UCEC	chr7	101206237	3'UTR	novel		0.5
UCEC	chr7	101207668	Missense_Mutation	novel	K615N	0.43
UCEC	chr7	101212845	Frame_Shift_Del	NA	*Q293Sfs65**	0.16
UCEC	chr7	101210540	Nonsense_Mutation	rs762008131	R498*	0.33
UCEC	chr7	101211707	Silent	rs773283750	I414I	0.34
UCEC	chr7	101213148	Missense_Mutation	rs766261555	D246N	0.22
UCEC	chr7	101212845	Frame_Shift_Del	NA	*Q293Sfs65**	0.4
UCEC	chr7	101211686	Silent	rs569043180	H421H	0.17
UCEC	chr7	101211902	Silent	rs368065819	D392D	0.37
UCEC	chr7	101217638	5'UTR	novel		0.5
UCEC	chr7	101206428	Silent	NA	G690G	0.81
UCEC	chr7	101210346	Silent	NA	I533I	0.27
UCEC	chr7	101207655	Missense_Mutation	rs201613747	E620K	0.39
UCEC	chr7	101216418	Missense_Mutation	rs551969292	F110L	0.38
UCEC	chr7	101206800	Silent	novel	N680N	0.33
UCEC	chr7	101208862	Silent	rs775700406	G593G	0.32
UCEC	chr7	101215919	Missense_Mutation	novel	P202S	0.31
UCEC	chr7	101216757	Missense_Mutation	novel	A47T	0.16
UCEC	chr7	101216444	Missense_Mutation	novel	D102N	0.2
UCEC	chr7	101206315	Missense_Mutation	novel	T728K	0.2	2OG-FeII_Oxy
UCEC	chr7	101211868	Missense_Mutation	rs143428253	R404C	0.41
UCEC	chr7	101216309	Missense_Mutation	novel	A119V	0.4
UCEC	chr7	101217954	5'Flank	novel		0.4
UCEC	chr7	101215952	Missense_Mutation	rs143734860	D191N	0.52
UCEC	chr7	101212916	Missense_Mutation	rs377320080	V269I	0.48
UCEC	chr7	101211629	Silent	novel	R440R	0.25
UCEC	chr7	101216763	Missense_Mutation	novel	A45T	0.22
UCEC	chr7	101216723	Missense_Mutation	novel	S58F	0.45
UCEC	chr7	101216785	Missense_Mutation	novel	E37D	0.28
UCEC	chr7	101212646	Frame_Shift_Del	rs780620804	*R297Gfs61**	0.47
UCEC	chr7	101212844	Frame_Shift_Ins	rs746342377	*Q293Afs48**	0.41
UCEC	chr7	101210406	Silent	rs768117675	G513G	0.1
UCEC	chr7	101216278	Silent	novel	F129F	0.38
UCEC	chr7	101212646	Frame_Shift_Del	rs780620804	*R297Gfs61**	0.28
UCEC	chr7	101212930	Missense_Mutation	novel	Y264C	0.3
UCEC	chr7	101216713	Missense_Mutation	novel	F61L	0.27
UCEC	chr7	101208865	Silent	rs145632943	G592G	0.5
UCEC	chr7	101216448	Silent	rs142046202	Y100Y	0.36
UCEC	chr7	101216181	Missense_Mutation	rs748424624	R162C	0.4
UCEC	chr7	101216278	Silent	novel	F129F	0.35
UCEC	chr7	101207607	Missense_Mutation	rs200112480	E636K	0.13
UCEC	chr7	101206389	Silent	rs755819791	P703P	0.26
UCEC	chr7	101206871	Missense_Mutation	rs747745259	R657W	0.24	2OG-FeII_Oxy
UCEC	chr7	101206897	Missense_Mutation	rs779308242	A648V	0.43
UCEC	chr7	101212648	Missense_Mutation	rs143577626	P296L	0.48
UCEC	chr7	101210386	Missense_Mutation	NA	R520I	0.17
UCEC	chr7	101206229	3'UTR	novel		0.3
UCEC	chr7	101212844	Frame_Shift_Ins	rs746342377	*Q293Afs48**	0.5
UCEC	chr7	101206897	Missense_Mutation	rs779308242	A648V	0.16
UCEC	chr7	101216319	Missense_Mutation	rs145634314	V116M	0.18
UCEC	chr7	101212646	Frame_Shift_Del	rs780620804	*R297Gfs61**	0.26
UCEC	chr7	101210540	Nonsense_Mutation	rs762008131	R498*	0.3
UCEC	chr7	101216197	Missense_Mutation	novel	E156D	0.37
UCEC	chr7	101216278	Silent	novel	F129F	0.37
UCEC	chr7	101212646	Frame_Shift_Del	rs780620804	*R297Gfs61**	0.58
UCEC	chr7	101212845	Frame_Shift_Del	NA	*Q293Sfs65**	0.32
UCEC	chr7	101212646	Frame_Shift_Del	rs780620804	*R297Gfs61**	0.39
UCEC	chr7	101213114	Missense_Mutation	novel	P257H	0.44
UCEC	chr7	101207587	Silent	rs770545398	Y642Y	0.49
UCEC	chr7	101211648	Missense_Mutation	novel	P434L	0.43
UCEC	chr7	101216697	Missense_Mutation	rs771521329	R67W	0.45

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
ACC	DEL	0.0556	0.12261
DLBC	AMP	0.2917	0.13215
LGG	AMP	0.2904	1.5525e-07
LIHC	DEL	0.0622	0.24831
PAAD	DEL	0.0435	0.049388
PRAD	AMP	0.1382	0.012709
TGCT	AMP	0.6267	0.035574
THCA	DEL	0.002	0.27619

Survival Analysis

Cancer	P-value	Q-value
THYM	0.006	Kaplan-Meier Survival Analysis
KIRC	0.026	Kaplan-Meier Survival Analysis
SARC	0.045	Kaplan-Meier Survival Analysis
MESO	0.00015	Kaplan-Meier Survival Analysis
ACC	0.0053	Kaplan-Meier Survival Analysis
HNSC	0.013	Kaplan-Meier Survival Analysis
LUSC	0.01	Kaplan-Meier Survival Analysis
COAD	0.02	Kaplan-Meier Survival Analysis
CESC	0.0031	Kaplan-Meier Survival Analysis
READ	0.034	Kaplan-Meier Survival Analysis
KICH	0.0021	Kaplan-Meier Survival Analysis
GBM	0.0012	Kaplan-Meier Survival Analysis
LIHC	0.011	Kaplan-Meier Survival Analysis
THCA	0.035	Kaplan-Meier Survival Analysis
LUAD	0.026	Kaplan-Meier Survival Analysis
UVM	0.00026	Kaplan-Meier Survival Analysis

Drugs

EuRBPDB

Description

RBDs

Expression

Transcripts

Gene Model

Pathways

Phenotypes

PPI

Orthologs

Gene Ontology

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742