EuRBPDB

Basic Information
Cancer Related Information

Description

RBPome

Literatures

Expression

Transcripts

Gene Model

Phenotypes

GWAS

PPI

Gene Ontology

Description

Ensembl ID: ENSG00000107554 (Gene tree)
Gene ID: 23268
Gene Symbol: DNMBP
Alias: KIAA1010|Tuba|ARHGEF36
Full Name: dynamin binding protein
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Minus strand
Length: 134,373 bases
Position: chr10:99,875,576-100,009,948
Accession: 30373
RBP type: non-canonical RBP
Summary: This gene encodes a protein belonging to the guanine nucleotide exchange factor family, and which regulates the configuration of cell junctions. It contains multiple binding sites for dynamin and thus links dynamin to actin regulatory proteins. Polymorphisms in this gene have been linked to Alzheimer's disease in some populations, though there are conflicting reports of such linkages in other populations. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
21232816	Dynamin binding protein gene expression and memory performance in aged rats.	Neurobiol Aging	2012 Mar	Casoli T	doi: 10.1016/j.neurobiolaging.2010.11.012

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000324109	DNMBP-201	6400	XM_006717735	ENSP00000315659	1577 (aa)	XP_006717798	Q6XZF7
ENST00000543621	DNMBP-203	4178	-	ENSP00000443657	865 (aa)	-	A0A1C7CYY6
ENST00000636706	DNMBP-204	5437	-	ENSP00000489875	1209 (aa)	-	A0A1B0GTX1
ENST00000472036	DNMBP-202	900	-	-	- (aa)	-	-

Gene Model

Click here to download ENSG00000107554's gene model file

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000107554	Platelet Function Tests	2.1891700E-005	-

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000107554	rs2805495	10	99934728	?	Adolescent idiopathic scoliosis	30019117			EFO_0005423

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000107554's network

* RBP PPI network refers to all genes directly bind to RBP

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0005089	Rho guanyl-nucleotide exchange factor activity	21873635.	IBA	Function
GO:0005089	Rho guanyl-nucleotide exchange factor activity	17015620.	IDA	Function
GO:0005515	protein binding	16413298.17015620.18654987.	IPI	Function
GO:0005794	Golgi apparatus	-	ISS	Component
GO:0005795	Golgi stack	-	IEA	Component
GO:0005856	cytoskeleton	-	IEA	Component
GO:0005911	cell-cell junction	17015620.	IDA	Component
GO:0007568	aging	-	IEA	Process
GO:0008360	regulation of cell shape	17015620.	IMP	Process
GO:0035023	regulation of Rho protein signal transduction	-	IEA	Process
GO:0035556	intracellular signal transduction	-	IEA	Process
GO:0045202	synapse	-	ISS	Component
GO:0098793	presynapse	-	ISS	Component

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq
BLCA	chr10	99880175	Missense_Mutation	novel	T1395I	0.31
BLCA	chr10	99885851	Missense_Mutation	novel	G1212S	0.75
BLCA	chr10	99957096	Silent	novel	L126L	0.13
BLCA	chr10	99957237	Intron	novel		0.5
BLCA	chr10	99955791	Silent	novel	K561K	0.18
BLCA	chr10	99898097	Missense_Mutation	rs755577741	R970Q	0.27
BLCA	chr10	99888857	Missense_Mutation	rs770100956	R1085C	0.44
BLCA	chr10	99956135	Missense_Mutation	novel	L447F	0.44
BLCA	chr10	99879892	Silent	NA	L1489L	0.24
BLCA	chr10	99955436	Missense_Mutation	novel	H680D	0.3
BLCA	chr10	99956026	Missense_Mutation	novel	S483Y	0.39
BLCA	chr10	99877256	Silent	novel	L1543L	0.26
BLCA	chr10	99955345	Missense_Mutation	novel	R710T	0.15
BRCA	chr10	99888932	Missense_Mutation	NA	V1060M	0.38
BRCA	chr10	99909006	Missense_Mutation	rs746675281	R801W	0.4
BRCA	chr10	99886549	In_Frame_Del	novel	T1115_K1123del	0.05
BRCA	chr10	99884054	Missense_Mutation	NA	K1318N	0.3
BRCA	chr10	99879892	Silent	novel	L1489L	0.06
BRCA	chr10	99955996	Missense_Mutation	NA	R493K	0.39
BRCA	chr10	99888867	Silent	novel	E1081E	0.13
BRCA	chr10	99877281	Nonsense_Mutation	NA	S1535*	0.12
BRCA	chr10	99955488	Silent	NA	L662L	0.13
BRCA	chr10	99899980	Missense_Mutation	NA	E881K	0.57
BRCA	chr10	99877281	Nonsense_Mutation	NA	S1535*	0.05
BRCA	chr10	99884120	Missense_Mutation	NA	F1296L	0.31
BRCA	chr10	99884170	Missense_Mutation	NA	L1280I	0.41
BRCA	chr10	99880133	Missense_Mutation	novel	P1409Q	0.03
BRCA	chr10	99955709	Missense_Mutation	novel	V589I	0.09
BRCA	chr10	99969117	Missense_Mutation	rs777394328	R89Q	0.26
BRCA	chr10	99886534	Silent	NA	L1128L	0.21
BRCA	chr10	99957264	Intron	NA		0.32
CESC	chr10	99955905	Missense_Mutation	NA	M523I	0.22
CESC	chr10	99956435	Missense_Mutation	rs766585897	E347K	0.23
CESC	chr10	99957111	Silent	novel	V121V	0.39
CESC	chr10	99972004	Missense_Mutation	novel	L41V	0.15
CESC	chr10	99930741	Intron	novel		0.43
CESC	chr10	99877255	Missense_Mutation	rs780955774	E1544K	0.41
CESC	chr10	99955634	Missense_Mutation	rs759618419	R614C	0.19
CESC	chr10	99885830	Missense_Mutation	novel	A1219T	0.13
CESC	chr10	99894986	Missense_Mutation	novel	S1039Y	0.37
CESC	chr10	99955683	Silent	rs752389732	T597T	0.46
CESC	chr10	99885758	Missense_Mutation	NA	P1243A	0.24
COAD	chr10	99955535	Missense_Mutation	NA	L647M	0.38
COAD	chr10	99884179	Missense_Mutation	rs745738512	R1277W	0.37
COAD	chr10	99957154	Missense_Mutation	NA	R107Q	0.41
COAD	chr10	99956973	Silent	NA	R167R	0.18
COAD	chr10	99886395	Missense_Mutation	rs770587503	A1175T	0.36
COAD	chr10	99956343	Silent	novel	D377D	0.22
COAD	chr10	99956663	Silent	novel	R271R	0.38
COAD	chr10	99886547	Missense_Mutation	NA	R1124H	0.46
COAD	chr10	99956325	Silent	NA	G383G	0.19
COAD	chr10	99956892	Frame_Shift_Del	NA	*P195Qfs5**	0.21
COAD	chr10	99877065	3'UTR	novel		0.32
COAD	chr10	99956833	Missense_Mutation	rs373777411	S214F	0.25
COAD	chr10	99900039	Missense_Mutation	NA	E861G	0.26
COAD	chr10	99898097	Missense_Mutation	rs755577741	R970Q	0.22
COAD	chr10	99880168	Frame_Shift_Del	novel	*S1398Lfs25**	0.16
COAD	chr10	99955420	Missense_Mutation	novel	L685R	0.08
COAD	chr10	99898139	Missense_Mutation	rs752522080	A956V	0.14
COAD	chr10	99956066	Frame_Shift_Del	NA	*T470Lfs20**	0.31
COAD	chr10	99956140	Missense_Mutation	novel	D445G	0.44
COAD	chr10	99879970	Silent	rs769113426	P1463P	0.1
COAD	chr10	99886301	Missense_Mutation	rs770552124	S1206L	0.37
COAD	chr10	99956682	Silent	rs139271365	F264F	0.31
COAD	chr10	99956170	Missense_Mutation	NA	G435V	0.17
COAD	chr10	99955606	Missense_Mutation	novel	P623H	0.33
COAD	chr10	99955504	Missense_Mutation	rs115222765	A657V	0.19
ESCA	chr10	99894951	Missense_Mutation	novel	I1051V	0.16
ESCA	chr10	99898742	Splice_Site	novel	X907_splice	0.15
ESCA	chr10	99957094	Missense_Mutation	novel	S127F	0.15
ESCA	chr10	99956438	Missense_Mutation	novel	A346S	1
ESCA	chr10	99877281	Nonsense_Mutation	NA	S1535*	0.07
GBM	chr10	99895037	Missense_Mutation	NA	V1022A	0.45
GBM	chr10	99957022	Missense_Mutation	rs138795130	R151Q	0.37
GBM	chr10	99909084	Missense_Mutation	rs762082328	E775K	0.46
GBM	chr10	99955480	Missense_Mutation	rs760771243	R665Q	0.52
GBM	chr10	99877301	Missense_Mutation	novel	N1528K	0.05
GBM	chr10	99969188	Frame_Shift_Del	novel	*E66Rfs28**	0.2
GBM	chr10	99879949	Silent	novel	R1470R	0.63
GBM	chr10	99956160	Silent	rs746197175	P438P	0.1
GBM	chr10	99880088	Frame_Shift_Del	novel	*P1424Rfs29**	0.05
GBM	chr10	99971989	Missense_Mutation	novel	D46N	0.71
HNSC	chr10	99877110	3'UTR	novel		0.22
HNSC	chr10	99880107	Missense_Mutation	novel	L1418V	0.15
HNSC	chr10	99955463	Missense_Mutation	NA	E671Q	0.24
HNSC	chr10	99955676	Missense_Mutation	novel	E600Q	0.21
HNSC	chr10	99955323	Silent	novel	L717L	0.31
HNSC	chr10	99957132	Silent	novel	G114G	0.2
HNSC	chr10	99880172	Missense_Mutation	rs148968752	S1396L	0.19
HNSC	chr10	99888897	Silent	novel	E1071E	0.22
HNSC	chr10	99972037	Missense_Mutation	novel	E30K	0.24
HNSC	chr10	99956112	Missense_Mutation	novel	R454S	0.61
HNSC	chr10	99956342	Nonsense_Mutation	novel	E378*	0.22
HNSC	chr10	99898762	Splice_Site	novel	X901_splice	0.25
HNSC	chr10	99898193	Missense_Mutation	novel	N938I	0.15
HNSC	chr10	99957046	Missense_Mutation	rs371156348	P143L	0.21
HNSC	chr10	99886537	Missense_Mutation	novel	K1127N	0.25
HNSC	chr10	99972102	Missense_Mutation	NA	R8Q	0.36
KICH	chr10	99957155	Nonsense_Mutation	rs771715835	R107*	0.38
KIRP	chr10	99955746	Missense_Mutation	NA	H576Q	0.14
LAML	chr10	99884113	Missense_Mutation	novel	A1299T	0.15
LGG	chr10	99955897	Missense_Mutation	novel	G526V	0.15
LGG	chr10	99972124	Translation_Start_Site	NA	M1?	0.37
LGG	chr10	99972076	Missense_Mutation	rs373271192	V17I	0.15
LGG	chr10	99886476	Nonsense_Mutation	novel	E1148*	0.39
LIHC	chr10	99955621	Missense_Mutation	rs777776503	P618L	0.06
LIHC	chr10	99877063	3'UTR	novel		0.35
LIHC	chr10	99956778	Silent	novel	E232E	0.05
LUAD	chr10	99900040	Nonsense_Mutation	novel	E861*	0.41
LUAD	chr10	99877226	Missense_Mutation	novel	E1553D	0.25
LUAD	chr10	99886615	Silent	NA	R1101R	0.17
LUAD	chr10	99896326	Missense_Mutation	NA	I998V	0.17
LUAD	chr10	99956332	Missense_Mutation	NA	A381V	0.51
LUAD	chr10	99888924	Silent	novel	A1062A	0.23
LUAD	chr10	99955721	Missense_Mutation	novel	E585Q	0.08
LUAD	chr10	99956153	Missense_Mutation	novel	E441K	0.08
LUAD	chr10	99956885	Missense_Mutation	novel	G197C	0.12
LUAD	chr10	99879825	Missense_Mutation	NA	A1512S	0.32
LUAD	chr10	99956517	Missense_Mutation	NA	R319S	0.17
LUAD	chr10	99957022	Missense_Mutation	NA	R151L	0.2
LUAD	chr10	99886525	Missense_Mutation	NA	F1131L	0.51
LUAD	chr10	99888953	Nonsense_Mutation	novel	E1053*	0.46
LUSC	chr10	99896367	Missense_Mutation	rs753661989	S984N	0.09
LUSC	chr10	99955893	Silent	novel	P527P	0.06
LUSC	chr10	99955355	Missense_Mutation	NA	M707L	0.04
LUSC	chr10	99909142	Missense_Mutation	rs751240225	M755I	0.36
LUSC	chr10	99896269	Nonsense_Mutation	NA	Q1017*	0.5
LUSC	chr10	99956303	Nonsense_Mutation	novel	E391*	0.32
LUSC	chr10	99957081	Silent	NA	R131R	0.45
LUSC	chr10	99877184	Silent	NA	P1567P	0.42
LUSC	chr10	99955439	Missense_Mutation	novel	G679C	0.14
LUSC	chr10	99884127	Missense_Mutation	NA	R1294Q	0.38
LUSC	chr10	99880299	Missense_Mutation	novel	D1354Y	0.25
LUSC	chr10	99884045	Missense_Mutation	novel	M1321I	0.69
LUSC	chr10	99884046	Missense_Mutation	novel	M1321K	0.7
LUSC	chr10	99955980	Missense_Mutation	NA	Q498H	0.36
LUSC	chr10	99896388	Missense_Mutation	NA	Y977C	0.37
LUSC	chr10	99972119	Silent	novel	E2E	0.44
OV	chr10	99957264	Intron	novel		0.09
OV	chr10	99955748	Missense_Mutation	novel	H576Y	0.08
OV	chr10	99880188	Missense_Mutation	rs772574320	A1391T	0.42
OV	chr10	99957098	Missense_Mutation	novel	L126F	0.12
OV	chr10	99957264	Intron	novel		0.11
OV	chr10	99957162	Silent	novel	L104L	0.05
OV	chr10	99877102	3'UTR	rs371790735		0.52
OV	chr10	99886457	Missense_Mutation	rs547189728	R1154Q	0.4
OV	chr10	99955950	Missense_Mutation	novel	K508N	0.05
OV	chr10	99955951	Frame_Shift_Ins	novel	*K508Tfs24**	0.05
OV	chr10	99956091	Silent	NA	P461P	0.38
OV	chr10	99972076	Missense_Mutation	rs373271192	V17I	0.15
OV	chr10	99884157	Missense_Mutation	NA	Y1284C	0.37
OV	chr10	99879899	Frame_Shift_Ins	novel	*Q1487Lfs25**	0.04
OV	chr10	99877299	Missense_Mutation	novel	P1529L	0.08
OV	chr10	99877301	Silent	novel	N1528N	0.08
OV	chr10	99900004	Missense_Mutation	NA	H873N	0.09
PAAD	chr10	99957070	Missense_Mutation	novel	S135Y	0.11
PAAD	chr10	99877049	3'UTR	novel		0.11
PAAD	chr10	99886450	Missense_Mutation	novel	N1156K	0.19
PAAD	chr10	99894984	Missense_Mutation	rs763772923	F1040L	0.16
PAAD	chr10	99900000	Missense_Mutation	novel	D874G	0.15
PRAD	chr10	99880132	Silent	rs750532651	P1409P	0.15
PRAD	chr10	99972028	Missense_Mutation	novel	A33T	0.38
READ	chr10	99880348	Silent	rs779422875	F1337F	0.33
READ	chr10	99956662	Missense_Mutation	NA	R271Q	0.42
READ	chr10	99896308	Missense_Mutation	NA	V1004F	0.32
READ	chr10	99908036	Missense_Mutation	novel	S838L	0.38
READ	chr10	99957211	Splice_Region	novel		0.3
READ	chr10	99955758	Missense_Mutation	novel	K572N	0.19
READ	chr10	99969230	Silent	rs746639347	F51F	0.21
SARC	chr10	99957024	Silent	novel	A150A	0.41
SARC	chr10	99929616	Intron	novel		0.73
SKCM	chr10	99884172	Missense_Mutation	NA	S1279F	0.36
SKCM	chr10	99886615	Silent	NA	R1101R	0.45
SKCM	chr10	99955359	Silent	novel	L705L	0.23
SKCM	chr10	99885778	Missense_Mutation	novel	T1236S	0.07
SKCM	chr10	99880133	Missense_Mutation	rs780193965	P1409L	0.11
SKCM	chr10	99955765	Missense_Mutation	novel	P570L	0.49
SKCM	chr10	99956825	Nonsense_Mutation	NA	Q217*	0.4
SKCM	chr10	99956890	Missense_Mutation	NA	P195L	0.28
SKCM	chr10	99956891	Missense_Mutation	novel	P195S	0.15
SKCM	chr10	99955475	Missense_Mutation	rs773314168	R667C	0.26
SKCM	chr10	99956130	Silent	NA	P448P	0.21
SKCM	chr10	99972103	Nonsense_Mutation	rs755674215	R8*	0.3
SKCM	chr10	99894960	Missense_Mutation	rs748732699	L1048F	0.28
SKCM	chr10	99896396	Splice_Region	NA	V974V	0.22
SKCM	chr10	99909130	Silent	novel	S759S	0.17
SKCM	chr10	99879926	Missense_Mutation	NA	S1478F	0.68
SKCM	chr10	99880237	Silent	NA	F1374F	0.65
SKCM	chr10	99900044	Silent	novel	R859R	0.39
SKCM	chr10	99888836	Missense_Mutation	NA	F1092L	0.41
SKCM	chr10	99956219	Missense_Mutation	NA	P419S	0.29
SKCM	chr10	99884118	Missense_Mutation	rs116046885	N1297S	0.5
SKCM	chr10	99877066	3'UTR	novel		0.19
SKCM	chr10	99956213	Missense_Mutation	NA	H421Y	0.06
SKCM	chr10	99956272	Missense_Mutation	NA	P401L	0.21
SKCM	chr10	99955631	Missense_Mutation	NA	P615S	0.44
SKCM	chr10	99877305	Missense_Mutation	NA	R1527Q	0.09
SKCM	chr10	99895011	Nonsense_Mutation	rs756073047	R1031*	0.24
SKCM	chr10	99955400	Missense_Mutation	rs148247428	P692S	1
SKCM	chr10	99955401	Silent	novel	C691C	1
SKCM	chr10	99956060	Nonsense_Mutation	NA	Q472*	0.43
SKCM	chr10	99896349	Missense_Mutation	NA	S990F	0.3
SKCM	chr10	99877259	Silent	novel	I1542I	0.17
SKCM	chr10	99956890	Missense_Mutation	NA	P195L	0.37
SKCM	chr10	99969229	Missense_Mutation	NA	P52S	0.48
STAD	chr10	99955770	Silent	NA	T568T	0.21
STAD	chr10	99956297	Missense_Mutation	NA	E393K	0.07
STAD	chr10	99898151	Missense_Mutation	NA	N952I	0.22
STAD	chr10	99896388	Missense_Mutation	NA	Y977C	0.14
STAD	chr10	99877045	3'UTR	novel		0.4
STAD	chr10	99885818	Missense_Mutation	rs374602494	E1223K	0.17
STAD	chr10	99956398	Missense_Mutation	NA	S359Y	0.4
STAD	chr10	99888871	Missense_Mutation	novel	F1080S	0.35
STAD	chr10	99969182	Silent	NA	G67G	0.11
STAD	chr10	99956076	Silent	NA	S466S	0.09
STAD	chr10	99957074	Missense_Mutation	NA	H134N	0.13
STAD	chr10	99877249	Missense_Mutation	NA	K1546E	0.05
STAD	chr10	99880139	Missense_Mutation	NA	S1407Y	0.21
STAD	chr10	99955916	Missense_Mutation	NA	R520G	0.35
STAD	chr10	99956276	Missense_Mutation	NA	S400T	0.11
STAD	chr10	99908959	Missense_Mutation	novel	Q816H	0.23
STAD	chr10	99896379	Missense_Mutation	NA	G980D	0.18
STAD	chr10	99877148	3'UTR	novel		0.31
STAD	chr10	99884170	Missense_Mutation	NA	L1280I	0.1
STAD	chr10	99896284	Missense_Mutation	NA	T1012A	0.17
THYM	chr10	99877215	Missense_Mutation	novel	A1557V	0.25
UCEC	chr10	99898161	Missense_Mutation	NA	P949T	0.4
UCEC	chr10	99908096	Splice_Site	NA	X819_splice	0.26
UCEC	chr10	99929756	Intron	novel		0.13
UCEC	chr10	99895011	Nonsense_Mutation	rs756073047	R1031*	0.33
UCEC	chr10	99908005	Silent	NA	S848S	0.32
UCEC	chr10	99956141	Missense_Mutation	NA	D445N	0.29
UCEC	chr10	99957265	Intron	novel		0.27
UCEC	chr10	99969219	Missense_Mutation	NA	F55C	0.28
UCEC	chr10	99880300	Silent	rs760687146	S1353S	0.16
UCEC	chr10	99930631	Intron	novel		0.33
UCEC	chr10	99956333	Missense_Mutation	rs774163097	A381T	0.32
UCEC	chr10	99956652	Silent	rs369854167	A274A	0.35
UCEC	chr10	99880024	Silent	novel	R1445R	0.4
UCEC	chr10	99908991	Missense_Mutation	novel	C806G	0.07
UCEC	chr10	99930301	Intron	novel		0.39
UCEC	chr10	99877215	Missense_Mutation	novel	A1557D	0.42
UCEC	chr10	99896289	Missense_Mutation	NA	H1010R	0.46
UCEC	chr10	99955825	Missense_Mutation	rs114457904	S550L	0.53
UCEC	chr10	99955481	Nonsense_Mutation	NA	R665*	0.26
UCEC	chr10	99879922	Silent	novel	V1479V	0.37
UCEC	chr10	99880209	Missense_Mutation	novel	T1384S	0.4
UCEC	chr10	99898224	Missense_Mutation	rs768367286	R928C	0.39
UCEC	chr10	99955553	Missense_Mutation	novel	P641S	0.52
UCEC	chr10	99955758	Missense_Mutation	novel	K572N	0.4
UCEC	chr10	99929731	Intron	novel		0.36
UCEC	chr10	99956741	Missense_Mutation	novel	G245W	0.17
UCEC	chr10	99877215	Missense_Mutation	novel	A1557D	0.48
UCEC	chr10	99898234	Silent	novel	Q924Q	0.47
UCEC	chr10	99955305	Missense_Mutation	novel	Q723H	0.28
UCEC	chr10	99886301	Missense_Mutation	rs770552124	S1206L	0.19
UCEC	chr10	99886386	Missense_Mutation	NA	L1178I	0.24
UCEC	chr10	99879843	Nonsense_Mutation	NA	E1506*	0.15
UCEC	chr10	99955284	Missense_Mutation	novel	E730D	0.17
UCEC	chr10	99956264	Missense_Mutation	novel	D404N	0.08
UCEC	chr10	99956306	Missense_Mutation	rs201994777	V390M	0.14
UCEC	chr10	99909034	Silent	novel	E791E	0.06
UCEC	chr10	99955587	Missense_Mutation	NA	Q629H	0.47
UCEC	chr10	99956359	Missense_Mutation	NA	R372I	0.44
UCEC	chr10	99956068	Missense_Mutation	novel	K469T	0.06
UCEC	chr10	99877044	3'UTR	novel		0.37
UCEC	chr10	99898101	Missense_Mutation	rs141749735	R969W	0.3
UCEC	chr10	99929734	Intron	novel		0.41
UCEC	chr10	99877144	3'UTR	rs774391965		0.23
UCEC	chr10	99888915	Missense_Mutation	novel	M1065I	0.23
UCEC	chr10	99886547	Missense_Mutation	NA	R1124H	0.41
UCEC	chr10	99888886	Missense_Mutation	rs184810563	R1075Q	0.41
UCEC	chr10	99955950	Frame_Shift_Ins	novel	*H509Afs39**	0.31
UCEC	chr10	99956917	Frame_Shift_Ins	novel	*E186Gfs25**	0.44
UCEC	chr10	99955693	Missense_Mutation	novel	K594T	0.36
UCEC	chr10	99957189	Silent	rs566667971	L95L	0.56
UCEC	chr10	99886395	Missense_Mutation	rs770587503	A1175T	0.32
UCEC	chr10	99888856	Missense_Mutation	rs759738167	R1085H	0.53
UCEC	chr10	99909140	Missense_Mutation	rs777158639	T756M	0.4
UCEC	chr10	99929847	Intron	novel		0.36
UCEC	chr10	99877262	Missense_Mutation	novel	K1541N	0.53
UCEC	chr10	99957064	Missense_Mutation	novel	S137N	0.38
UCEC	chr10	99956108	Missense_Mutation	NA	Y456H	0.44
UCEC	chr10	99956270	Frame_Shift_Ins	novel	*T402Ffs16**	0.02
UCEC	chr10	99957083	Missense_Mutation	rs772943085	R131W	0.42
UCEC	chr10	99877196	Missense_Mutation	NA	K1563N	0.12
UCEC	chr10	99969166	Missense_Mutation	novel	C73R	0.33
UCEC	chr10	99898152	Missense_Mutation	novel	N952D	0.33
UCEC	chr10	99900008	Missense_Mutation	novel	Q871H	0.34
UCEC	chr10	99957062	Missense_Mutation	novel	A138S	0.37
UCEC	chr10	99957136	Missense_Mutation	rs370012463	R113Q	0.42
UCEC	chr10	99955824	Silent	rs774498401	S550S	0.53
UCEC	chr10	99894971	Missense_Mutation	rs764742137	L1044P	0.36
UCEC	chr10	99894978	Nonsense_Mutation	NA	R1042*	0.42
UCEC	chr10	99880299	Missense_Mutation	rs772987204	D1354N	0.26
UCEC	chr10	99956503	Missense_Mutation	NA	S324Y	0.37
UCEC	chr10	99956905	Missense_Mutation	rs202042155	R190Q	0.36
UCEC	chr10	99956892	Frame_Shift_Del	NA	*P195Qfs5**	0.36
UCEC	chr10	99930218	Intron	novel		0.18
UCEC	chr10	99930330	Intron	novel		0.24
UCEC	chr10	99877310	Missense_Mutation	novel	K1525N	0.17
UCEC	chr10	99955527	Silent	novel	P649P	0.29
UCEC	chr10	99956634	Nonsense_Mutation	rs758275310	W280*	0.32
UCEC	chr10	99957264	Intron	NA		0.56
UCEC	chr10	99957022	Missense_Mutation	rs138795130	R151Q	0.43
UCEC	chr10	99957045	Silent	rs201587745	P143P	0.31
UCEC	chr10	99929628	Intron	novel		0.13
UCEC	chr10	99957045	Silent	rs201587745	P143P	0.06
UCEC	chr10	99955555	Missense_Mutation	rs771129840	R640Q	0.53
UCEC	chr10	99884100	Missense_Mutation	novel	D1303G	0.36
UCEC	chr10	99908969	Missense_Mutation	NA	P813L	0.46
UCEC	chr10	99908027	Missense_Mutation	novel	L841S	0.41
UCEC	chr10	99972067	Nonsense_Mutation	novel	E20*	0.25
UCEC	chr10	99886422	Missense_Mutation	novel	D1166Y	0.25
UCEC	chr10	99899926	Missense_Mutation	novel	D899Y	0.22
UCEC	chr10	99955504	Missense_Mutation	rs115222765	A657V	0.23
UCEC	chr10	99957253	Intron	novel		0.28
UCEC	chr10	99877281	Nonsense_Mutation	NA	S1535*	0.08
UCEC	chr10	99886330	Missense_Mutation	NA	Q1196H	0.32
UCEC	chr10	99894972	Missense_Mutation	NA	L1044M	0.14
UCEC	chr10	99955767	Missense_Mutation	NA	E569D	0.16
UCEC	chr10	99930710	Intron	novel		0.41
UCEC	chr10	99955474	Missense_Mutation	rs375606736	R667H	0.41
UCEC	chr10	99969225	Missense_Mutation	novel	S53N	0.06
UCEC	chr10	99956931	Silent	novel	G181G	0.4
UCEC	chr10	99957211	Splice_Region	novel		0.24
UCS	chr10	99955560	Silent	novel	V638V	0.12
UCS	chr10	99877314	Missense_Mutation	novel	F1524S	0.36

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
ACC	DEL	0.1	0.19593
CHOL	DEL	0.2222	0.048655
COAD	DEL	0.1774	9.4741e-07
MESO	DEL	0.2759	0.00015289
OV	DEL	0.399	5.3759e-12
PAAD	DEL	0.1359	0.169
READ	DEL	0.2485	0.014135
THCA	DEL	0.016	0.011063
THYM	DEL	0.0325	0.10563
UCS	DEL	0.3036	0.1218

Survival Analysis

Cancer	P-value	Q-value
KIRC	0.0001	Kaplan-Meier Survival Analysis
MESO	0.042	Kaplan-Meier Survival Analysis
SKCM	0.0069	Kaplan-Meier Survival Analysis
PRAD	0.041	Kaplan-Meier Survival Analysis
KIRP	0.00011	Kaplan-Meier Survival Analysis
PAAD	0.012	Kaplan-Meier Survival Analysis
BLCA	0.0015	Kaplan-Meier Survival Analysis
UCEC	0.0001	Kaplan-Meier Survival Analysis
LGG	0.00025	Kaplan-Meier Survival Analysis
THCA	0.041	Kaplan-Meier Survival Analysis

Drugs

EuRBPDB

Description

RBPome

Literatures

Expression

Transcripts

Gene Model

Phenotypes

GWAS

PPI

Gene Ontology

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Input Drug :

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Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742