EuRBPDB

Basic Information
Cancer Related Information

Description

RBDs

RBPome

Expression

Transcripts

Gene Model

Pathways

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000108107 (Gene tree)
Gene ID: 6158
Gene Symbol: RPL28
Alias: FLJ43307|L28
Full Name: ribosomal protein L28
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Plus strand
Length: 18,150 bases
Position: chr19:55,385,101-55,403,250
Accession: 10330
RBP type: canonical RBP
Summary: Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L28E family of ribosomal proteins. It is located in the cytoplasm. Variable expression of this gene in colorectal cancers compared to adjacent normal tissues has been observed, although no correlation between the level of expression and the severity of the disease has been found. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Oct 2008]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000342787	Ribosomal_L28e	PF01778.17	3.1e-35	1	1
ENSP00000453319	Ribosomal_L28e	PF01778.17	3.1e-35	1	1
ENSP00000452909	Ribosomal_L28e	PF01778.17	1.3e-30	1	1
ENSP00000452763	Ribosomal_L28e	PF01778.17	1.4e-30	1	1
ENSP00000453029	Ribosomal_L28e	PF01778.17	6.1e-30	1	1
ENSP00000391665	Ribosomal_L28e	PF01778.17	2.4e-19	1	1
ENSP00000400596	Ribosomal_L28e	PF01778.17	3.4e-19	1	1
ENSP00000453584	Ribosomal_L28e	PF01778.17	3.4e-19	1	1
ENSP00000453285	Ribosomal_L28e	PF01778.17	2.3e-17	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
29431736	Capturing the interactome of newly transcribed RNA	RIC & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
22658674	Insights into RNA biology from an atlas of mammalian mRNA-binding proteins	RIC & Hela	2012 May 31	Castello A	DOI: 10.1016/j.cell.2012.04.031
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
27453046	Comprehensive Identification of RNA-Binding Domains in Human Cells	RIC & Hela	2016 Aug 18	Castello A	DOI: 10.1016/j.molcel.2016.06.029

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000431533	RPL28-204	590	-	ENSP00000400596	87 (aa)	-	P46779
ENST00000558752	RPL28-206	671	-	ENSP00000453584	112 (aa)	-	H0YMF4
ENST00000558815	RPL28-207	616	-	ENSP00000452909	169 (aa)	-	P46779
ENST00000428193	RPL28-203	573	-	ENSP00000391665	69 (aa)	-	P46779
ENST00000426763	RPL28-202	5620	-	-	- (aa)	-	-
ENST00000344063	RPL28-201	4796	-	ENSP00000342787	137 (aa)	-	P46779
ENST00000560881	RPL28-211	1692	-	-	- (aa)	-	-
ENST00000560583	RPL28-210	1204	-	ENSP00000453029	163 (aa)	-	P46779
ENST00000558131	RPL28-205	444	-	ENSP00000453285	89 (aa)	-	H0YLP6
ENST00000559463	RPL28-208	852	-	ENSP00000453319	137 (aa)	-	P46779
ENST00000560055	RPL28-209	670	XM_024451636	ENSP00000452763	170 (aa)	XP_024307404	H0YKD8

Gene Model

Click here to download ENSG00000108107's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa03010	Ribosome	KEGG

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000108107's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000108107	RPL28	97	85.075	ENSAPOG00000023913	rpl28	100	78.832	Acanthochromis_polyacanthus
ENSG00000108107	RPL28	100	98.540	ENSAMEG00000003764	RPL28	100	98.540	Ailuropoda_melanoleuca
ENSG00000108107	RPL28	99	83.824	ENSACIG00000014369	rpl28	100	79.562	Amphilophus_citrinellus
ENSG00000108107	RPL28	97	83.582	ENSAOCG00000019874	rpl28	94	78.102	Amphiprion_ocellaris
ENSG00000108107	RPL28	97	83.582	ENSAPEG00000020972	rpl28	100	78.102	Amphiprion_percula
ENSG00000108107	RPL28	99	83.824	ENSATEG00000013839	rpl28	100	78.832	Anabas_testudineus
ENSG00000108107	RPL28	96	66.667	ENSACAG00000006100	-	100	61.314	Anolis_carolinensis
ENSG00000108107	RPL28	99	91.176	ENSACAG00000015980	-	100	86.131	Anolis_carolinensis
ENSG00000108107	RPL28	100	99.270	ENSANAG00000034536	RPL28	100	99.270	Aotus_nancymaae
ENSG00000108107	RPL28	99	85.294	ENSACLG00000027917	rpl28	98	80.292	Astatotilapia_calliptera
ENSG00000108107	RPL28	99	79.412	ENSAMXG00000042541	rpl28	100	73.723	Astyanax_mexicanus
ENSG00000108107	RPL28	100	97.810	ENSBTAG00000023343	RPL28	66	97.810	Bos_taurus
ENSG00000108107	RPL28	94	44.776	WBGene00004442	rpl-28	91	38.211	Caenorhabditis_elegans
ENSG00000108107	RPL28	100	99.270	ENSCJAG00000000869	RPL28	100	99.270	Callithrix_jacchus
ENSG00000108107	RPL28	100	98.540	ENSCAFG00000002585	RPL28	100	98.540	Canis_familiaris
ENSG00000108107	RPL28	100	97.810	ENSCAFG00020024049	-	100	97.810	Canis_lupus_dingo
ENSG00000108107	RPL28	90	95.161	ENSCAFG00020007821	-	54	89.706	Canis_lupus_dingo
ENSG00000108107	RPL28	100	98.540	ENSCAFG00020015496	-	100	98.540	Canis_lupus_dingo
ENSG00000108107	RPL28	93	71.654	ENSCHIG00000010485	-	89	71.654	Capra_hircus
ENSG00000108107	RPL28	100	97.080	ENSCHIG00000025540	-	100	97.080	Capra_hircus
ENSG00000108107	RPL28	100	67.153	ENSTSYG00000035503	-	100	67.153	Carlito_syrichta
ENSG00000108107	RPL28	84	86.957	ENSTSYG00000032922	-	98	86.957	Carlito_syrichta
ENSG00000108107	RPL28	100	70.073	ENSTSYG00000036697	-	90	70.073	Carlito_syrichta
ENSG00000108107	RPL28	100	99.270	ENSTSYG00000033853	RPL28	100	99.270	Carlito_syrichta
ENSG00000108107	RPL28	100	97.080	ENSCAPG00000007161	-	100	97.080	Cavia_aperea
ENSG00000108107	RPL28	100	98.540	ENSCPOG00000012833	-	100	98.540	Cavia_porcellus
ENSG00000108107	RPL28	100	96.350	ENSCPOG00000023112	-	100	96.350	Cavia_porcellus
ENSG00000108107	RPL28	100	86.131	ENSCCAG00000018730	-	100	86.131	Cebus_capucinus
ENSG00000108107	RPL28	100	99.270	ENSCCAG00000025765	RPL28	100	99.270	Cebus_capucinus
ENSG00000108107	RPL28	100	73.723	ENSCCAG00000003452	-	100	73.723	Cebus_capucinus
ENSG00000108107	RPL28	99	77.941	ENSCCAG00000012793	-	100	75.912	Cebus_capucinus
ENSG00000108107	RPL28	96	80.303	ENSCCAG00000034537	-	99	82.927	Cebus_capucinus
ENSG00000108107	RPL28	99	73.529	ENSCATG00000039353	-	99	73.529	Cercocebus_atys
ENSG00000108107	RPL28	100	100.000	ENSCATG00000031417	RPL28	100	100.000	Cercocebus_atys
ENSG00000108107	RPL28	100	98.540	ENSCLAG00000000684	RPL28	100	98.540	Chinchilla_lanigera
ENSG00000108107	RPL28	99	98.529	ENSCSAG00000018419	-	100	94.891	Chlorocebus_sabaeus
ENSG00000108107	RPL28	100	99.270	ENSCSAG00000001738	-	100	99.270	Chlorocebus_sabaeus
ENSG00000108107	RPL28	80	84.545	ENSCPBG00000008298	RPL28	67	84.545	Chrysemys_picta_bellii
ENSG00000108107	RPL28	96	68.182	ENSCSAVG00000008832	-	98	62.295	Ciona_savignyi
ENSG00000108107	RPL28	99	71.324	ENSCANG00000008828	-	99	71.324	Colobus_angolensis_palliatus
ENSG00000108107	RPL28	100	97.080	ENSCANG00000002437	-	100	97.080	Colobus_angolensis_palliatus
ENSG00000108107	RPL28	99	100.000	ENSCANG00000038322	RPL28	99	100.000	Colobus_angolensis_palliatus
ENSG00000108107	RPL28	100	97.080	ENSCANG00000021622	-	100	97.080	Colobus_angolensis_palliatus
ENSG00000108107	RPL28	100	81.022	ENSCGRG00001019521	-	100	81.022	Cricetulus_griseus_chok1gshd
ENSG00000108107	RPL28	100	98.540	ENSCGRG00001023644	Rpl28	100	98.540	Cricetulus_griseus_chok1gshd
ENSG00000108107	RPL28	83	78.070	ENSCGRG00000006958	-	86	78.070	Cricetulus_griseus_crigri
ENSG00000108107	RPL28	80	98.182	ENSCGRG00000004471	Rpl28	100	98.182	Cricetulus_griseus_crigri
ENSG00000108107	RPL28	97	85.075	ENSCSEG00000001312	rpl28	100	78.832	Cynoglossus_semilaevis
ENSG00000108107	RPL28	99	85.294	ENSCVAG00000022473	rpl28	100	79.562	Cyprinodon_variegatus
ENSG00000108107	RPL28	97	86.567	ENSDARG00000005791	rpl28	99	79.412	Danio_rerio
ENSG00000108107	RPL28	100	97.810	ENSDNOG00000044172	-	100	97.810	Dasypus_novemcinctus
ENSG00000108107	RPL28	99	67.677	ENSDNOG00000046131	RPL28	99	72.327	Dasypus_novemcinctus
ENSG00000108107	RPL28	100	97.810	ENSDORG00000012809	Rpl28	100	97.810	Dipodomys_ordii
ENSG00000108107	RPL28	94	50.746	FBgn0035422	RpL28	92	45.865	Drosophila_melanogaster
ENSG00000108107	RPL28	97	67.164	ENSEBUG00000009129	rpl28	84	67.593	Eptatretus_burgeri
ENSG00000108107	RPL28	100	98.540	ENSEASG00005020779	RPL28	100	98.540	Equus_asinus_asinus
ENSG00000108107	RPL28	100	100.000	ENSECAG00000026938	-	68	98.540	Equus_caballus
ENSG00000108107	RPL28	99	80.882	ENSELUG00000001730	rpl28	100	76.642	Esox_lucius
ENSG00000108107	RPL28	99	66.176	ENSFCAG00000040593	-	74	69.531	Felis_catus
ENSG00000108107	RPL28	100	97.810	ENSFCAG00000005639	-	100	97.810	Felis_catus
ENSG00000108107	RPL28	100	98.540	ENSFDAG00000021448	RPL28	100	98.540	Fukomys_damarensis
ENSG00000108107	RPL28	99	88.235	ENSFHEG00000007732	rpl28	81	81.022	Fundulus_heteroclitus
ENSG00000108107	RPL28	99	80.882	ENSGMOG00000015325	rpl28	100	74.453	Gadus_morhua
ENSG00000108107	RPL28	99	85.294	ENSGAFG00000012973	rpl28	100	79.562	Gambusia_affinis
ENSG00000108107	RPL28	97	85.075	ENSGACG00000016089	rpl28	100	77.372	Gasterosteus_aculeatus
ENSG00000108107	RPL28	99	91.176	ENSGAGG00000016908	RPL28	100	87.591	Gopherus_agassizii
ENSG00000108107	RPL28	100	100.000	ENSGGOG00000022653	-	100	100.000	Gorilla_gorilla
ENSG00000108107	RPL28	100	78.102	ENSGGOG00000027685	-	73	78.102	Gorilla_gorilla
ENSG00000108107	RPL28	99	85.294	ENSHBUG00000007390	rpl28	98	80.292	Haplochromis_burtoni
ENSG00000108107	RPL28	100	97.810	ENSHGLG00000009865	RPL28	100	97.810	Heterocephalus_glaber_female
ENSG00000108107	RPL28	100	97.810	ENSHGLG00100005407	RPL28	100	97.810	Heterocephalus_glaber_male
ENSG00000108107	RPL28	99	86.765	ENSHCOG00000003134	rpl28	100	80.292	Hippocampus_comes
ENSG00000108107	RPL28	99	83.824	ENSIPUG00000004935	rpl28	100	76.642	Ictalurus_punctatus
ENSG00000108107	RPL28	100	98.540	ENSSTOG00000008006	RPL28	100	98.540	Ictidomys_tridecemlineatus
ENSG00000108107	RPL28	100	98.540	ENSJJAG00000019841	Rpl28	100	98.540	Jaculus_jaculus
ENSG00000108107	RPL28	99	85.294	ENSKMAG00000011412	rpl28	100	79.562	Kryptolebias_marmoratus
ENSG00000108107	RPL28	99	82.353	ENSLBEG00000027857	rpl28	100	78.102	Labrus_bergylta
ENSG00000108107	RPL28	75	78.846	ENSLACG00000011783	RPL28	100	64.865	Latimeria_chalumnae
ENSG00000108107	RPL28	99	85.294	ENSLOCG00000003073	rpl28	93	81.022	Lepisosteus_oculatus
ENSG00000108107	RPL28	100	99.270	ENSLAFG00000022257	RPL28	100	99.270	Loxodonta_africana
ENSG00000108107	RPL28	100	100.000	ENSMFAG00000043131	RPL28	100	100.000	Macaca_fascicularis
ENSG00000108107	RPL28	100	100.000	ENSMMUG00000015901	RPL28	100	100.000	Macaca_mulatta
ENSG00000108107	RPL28	100	100.000	ENSMNEG00000032714	RPL28	100	100.000	Macaca_nemestrina
ENSG00000108107	RPL28	100	100.000	ENSMLEG00000039619	RPL28	100	100.000	Mandrillus_leucophaeus
ENSG00000108107	RPL28	100	78.652	ENSMLEG00000039498	-	100	78.652	Mandrillus_leucophaeus
ENSG00000108107	RPL28	99	85.294	ENSMAMG00000017519	rpl28	100	80.292	Mastacembelus_armatus
ENSG00000108107	RPL28	99	85.294	ENSMZEG00005002151	rpl28	98	80.292	Maylandia_zebra
ENSG00000108107	RPL28	99	92.647	ENSMAUG00000004738	-	100	83.212	Mesocricetus_auratus
ENSG00000108107	RPL28	100	98.540	ENSMAUG00000021147	-	100	98.540	Mesocricetus_auratus
ENSG00000108107	RPL28	97	69.173	ENSMAUG00000016592	-	80	69.173	Mesocricetus_auratus
ENSG00000108107	RPL28	100	75.912	ENSMAUG00000017070	-	100	75.912	Mesocricetus_auratus
ENSG00000108107	RPL28	100	98.540	ENSMAUG00000000783	-	100	98.540	Mesocricetus_auratus
ENSG00000108107	RPL28	100	98.540	ENSMICG00000000996	RPL28	100	98.540	Microcebus_murinus
ENSG00000108107	RPL28	100	80.292	ENSMICG00000033709	-	100	80.292	Microcebus_murinus
ENSG00000108107	RPL28	100	98.540	ENSMOCG00000006245	-	100	98.540	Microtus_ochrogaster
ENSG00000108107	RPL28	100	94.928	ENSMOCG00000006881	-	100	94.928	Microtus_ochrogaster
ENSG00000108107	RPL28	99	97.059	ENSMOCG00000008075	-	100	95.620	Microtus_ochrogaster
ENSG00000108107	RPL28	97	82.090	ENSMMOG00000004489	rpl28	100	75.182	Mola_mola
ENSG00000108107	RPL28	99	92.647	ENSMODG00000000275	RPL28	100	89.781	Monodelphis_domestica
ENSG00000108107	RPL28	99	82.353	ENSMALG00000004571	rpl28	100	77.372	Monopterus_albus
ENSG00000108107	RPL28	100	98.540	MGP_CAROLIEiJ_G0029130	Rpl28	100	98.540	Mus_caroli
ENSG00000108107	RPL28	100	98.540	ENSMUSG00000030432	Rpl28	100	98.540	Mus_musculus
ENSG00000108107	RPL28	100	97.810	MGP_PahariEiJ_G0020999	Rpl28	100	97.810	Mus_pahari
ENSG00000108107	RPL28	100	98.540	MGP_SPRETEiJ_G0030183	Rpl28	100	98.540	Mus_spretus
ENSG00000108107	RPL28	100	97.810	ENSMPUG00000007450	RPL28	100	97.810	Mustela_putorius_furo
ENSG00000108107	RPL28	100	94.891	ENSMLUG00000023198	-	100	94.891	Myotis_lucifugus
ENSG00000108107	RPL28	100	96.350	ENSMLUG00000023789	-	100	96.350	Myotis_lucifugus
ENSG00000108107	RPL28	94	69.767	ENSNGAG00000001032	-	100	69.767	Nannospalax_galili
ENSG00000108107	RPL28	100	98.540	ENSNGAG00000016459	Rpl28	84	98.540	Nannospalax_galili
ENSG00000108107	RPL28	99	85.294	ENSNBRG00000006729	rpl28	84	80.292	Neolamprologus_brichardi
ENSG00000108107	RPL28	100	100.000	ENSNLEG00000010503	-	100	100.000	Nomascus_leucogenys
ENSG00000108107	RPL28	100	71.533	ENSNLEG00000029689	-	100	71.533	Nomascus_leucogenys
ENSG00000108107	RPL28	50	97.059	ENSOPRG00000013428	-	100	97.059	Ochotona_princeps
ENSG00000108107	RPL28	100	97.080	ENSOPRG00000000463	-	100	97.080	Ochotona_princeps
ENSG00000108107	RPL28	100	98.540	ENSODEG00000010391	-	100	98.540	Octodon_degus
ENSG00000108107	RPL28	100	97.810	ENSODEG00000019864	-	100	97.810	Octodon_degus
ENSG00000108107	RPL28	100	95.620	ENSODEG00000020377	-	100	95.620	Octodon_degus
ENSG00000108107	RPL28	100	94.891	ENSODEG00000019117	-	100	94.891	Octodon_degus
ENSG00000108107	RPL28	99	85.294	ENSONIG00000007486	rpl28	100	80.292	Oreochromis_niloticus
ENSG00000108107	RPL28	100	98.540	ENSOCUG00000027112	-	100	98.540	Oryctolagus_cuniculus
ENSG00000108107	RPL28	99	92.647	ENSOCUG00000027875	-	100	90.580	Oryctolagus_cuniculus
ENSG00000108107	RPL28	99	85.294	ENSORLG00000005108	rpl28	100	79.562	Oryzias_latipes
ENSG00000108107	RPL28	99	85.294	ENSORLG00020007182	rpl28	100	79.562	Oryzias_latipes_hni
ENSG00000108107	RPL28	99	85.294	ENSORLG00015013944	rpl28	100	79.562	Oryzias_latipes_hsok
ENSG00000108107	RPL28	99	85.294	ENSOMEG00000009716	rpl28	100	79.562	Oryzias_melastigma
ENSG00000108107	RPL28	100	98.540	ENSOGAG00000025533	RPL28	100	98.540	Otolemur_garnettii
ENSG00000108107	RPL28	100	97.810	ENSOARG00000001428	RPL28	100	97.810	Ovis_aries
ENSG00000108107	RPL28	100	72.263	ENSPPAG00000032901	-	100	72.263	Pan_paniscus
ENSG00000108107	RPL28	100	100.000	ENSPPAG00000038000	-	100	100.000	Pan_paniscus
ENSG00000108107	RPL28	100	77.372	ENSPPAG00000034138	-	100	77.372	Pan_paniscus
ENSG00000108107	RPL28	100	68.613	ENSPPRG00000012498	-	100	68.613	Panthera_pardus
ENSG00000108107	RPL28	100	97.810	ENSPPRG00000012962	-	100	97.810	Panthera_pardus
ENSG00000108107	RPL28	97	70.000	ENSPPRG00000013998	-	85	65.942	Panthera_pardus
ENSG00000108107	RPL28	100	97.810	ENSPTIG00000011191	-	100	97.810	Panthera_tigris_altaica
ENSG00000108107	RPL28	100	100.000	ENSPTRG00000011505	RPL28	100	100.000	Pan_troglodytes
ENSG00000108107	RPL28	100	77.372	ENSPTRG00000043492	-	100	77.372	Pan_troglodytes
ENSG00000108107	RPL28	100	75.912	ENSPTRG00000043676	-	100	75.912	Pan_troglodytes
ENSG00000108107	RPL28	100	100.000	ENSPANG00000029716	RPL28	100	100.000	Papio_anubis
ENSG00000108107	RPL28	99	86.765	ENSPKIG00000014698	rpl28	99	81.618	Paramormyrops_kingsleyae
ENSG00000108107	RPL28	80	81.651	ENSPSIG00000015206	RPL28	84	81.651	Pelodiscus_sinensis
ENSG00000108107	RPL28	99	82.353	ENSPMGG00000004586	rpl28	100	76.642	Periophthalmus_magnuspinnatus
ENSG00000108107	RPL28	100	89.781	ENSPEMG00000013352	-	100	89.781	Peromyscus_maniculatus_bairdii
ENSG00000108107	RPL28	100	98.540	ENSPEMG00000011755	Rpl28	100	98.540	Peromyscus_maniculatus_bairdii
ENSG00000108107	RPL28	99	80.882	ENSPMAG00000008617	rpl28	96	79.104	Petromyzon_marinus
ENSG00000108107	RPL28	99	76.471	ENSPCIG00000019415	-	86	67.416	Phascolarctos_cinereus
ENSG00000108107	RPL28	94	83.077	ENSPCIG00000018601	-	95	79.365	Phascolarctos_cinereus
ENSG00000108107	RPL28	99	85.294	ENSPFOG00000002206	rpl28	100	80.292	Poecilia_formosa
ENSG00000108107	RPL28	99	85.294	ENSPLAG00000003206	rpl28	100	80.292	Poecilia_latipinna
ENSG00000108107	RPL28	99	85.294	ENSPMEG00000000595	rpl28	100	80.292	Poecilia_mexicana
ENSG00000108107	RPL28	99	85.294	ENSPREG00000002015	rpl28	100	80.292	Poecilia_reticulata
ENSG00000108107	RPL28	100	99.270	ENSPPYG00000010417	-	100	99.270	Pongo_abelii
ENSG00000108107	RPL28	84	81.034	ENSPPYG00000029517	-	76	82.353	Pongo_abelii
ENSG00000108107	RPL28	50	100.000	ENSPCAG00000012768	-	100	100.000	Procavia_capensis
ENSG00000108107	RPL28	100	88.321	ENSPCOG00000025957	-	100	88.321	Propithecus_coquereli
ENSG00000108107	RPL28	100	98.551	ENSPCOG00000017000	RPL28	100	98.551	Propithecus_coquereli
ENSG00000108107	RPL28	99	94.118	ENSPCOG00000014236	-	89	95.763	Propithecus_coquereli
ENSG00000108107	RPL28	100	95.620	ENSPCOG00000007456	-	100	95.620	Propithecus_coquereli
ENSG00000108107	RPL28	100	96.350	ENSPVAG00000007315	RPL28	100	96.350	Pteropus_vampyrus
ENSG00000108107	RPL28	99	85.294	ENSPNYG00000004757	rpl28	100	79.562	Pundamilia_nyererei
ENSG00000108107	RPL28	99	82.353	ENSPNAG00000003547	rpl28	92	75.912	Pygocentrus_nattereri
ENSG00000108107	RPL28	99	94.118	ENSRNOG00000061441	AABR07071935.1	100	92.701	Rattus_norvegicus
ENSG00000108107	RPL28	100	98.540	ENSRNOG00000017127	Rpl28	100	98.540	Rattus_norvegicus
ENSG00000108107	RPL28	100	97.080	ENSRNOG00000037673	AABR07071891.2	100	97.080	Rattus_norvegicus
ENSG00000108107	RPL28	99	97.059	ENSRNOG00000009240	AABR07016623.1	97	87.770	Rattus_norvegicus
ENSG00000108107	RPL28	100	98.540	ENSRBIG00000003677	-	100	98.540	Rhinopithecus_bieti
ENSG00000108107	RPL28	100	100.000	ENSRBIG00000034637	RPL28	100	100.000	Rhinopithecus_bieti
ENSG00000108107	RPL28	100	75.362	ENSRROG00000030502	-	100	67.153	Rhinopithecus_roxellana
ENSG00000108107	RPL28	100	100.000	ENSRROG00000028904	RPL28	100	100.000	Rhinopithecus_roxellana
ENSG00000108107	RPL28	100	67.883	ENSSBOG00000034324	-	100	67.883	Saimiri_boliviensis_boliviensis
ENSG00000108107	RPL28	100	99.270	ENSSBOG00000028286	RPL28	100	99.270	Saimiri_boliviensis_boliviensis
ENSG00000108107	RPL28	100	81.111	ENSSBOG00000022635	-	100	81.111	Saimiri_boliviensis_boliviensis
ENSG00000108107	RPL28	99	86.765	ENSSFOG00015012801	-	100	81.022	Scleropages_formosus
ENSG00000108107	RPL28	99	86.765	ENSSFOG00015001292	rpl28	100	81.022	Scleropages_formosus
ENSG00000108107	RPL28	99	83.824	ENSSMAG00000008756	rpl28	100	78.832	Scophthalmus_maximus
ENSG00000108107	RPL28	99	85.294	ENSSDUG00000015127	rpl28	100	78.832	Seriola_dumerili
ENSG00000108107	RPL28	71	39.394	ENSSLDG00000009395	-	79	39.394	Seriola_lalandi_dorsalis
ENSG00000108107	RPL28	99	83.824	ENSSLDG00000006440	-	86	74.390	Seriola_lalandi_dorsalis
ENSG00000108107	RPL28	99	83.824	ENSSLDG00000000414	rpl28	100	78.102	Seriola_lalandi_dorsalis
ENSG00000108107	RPL28	100	83.212	ENSSARG00000009741	RPL28	100	83.212	Sorex_araneus
ENSG00000108107	RPL28	97	92.537	ENSSPUG00000010390	RPL28	100	84.672	Sphenodon_punctatus
ENSG00000108107	RPL28	97	85.075	ENSSPAG00000015122	rpl28	72	79.562	Stegastes_partitus
ENSG00000108107	RPL28	84	75.862	ENSSSCG00000030430	-	87	66.942	Sus_scrofa
ENSG00000108107	RPL28	75	90.385	ENSSSCG00000039543	-	88	67.176	Sus_scrofa
ENSG00000108107	RPL28	100	97.810	ENSSSCG00000039460	-	100	97.810	Sus_scrofa
ENSG00000108107	RPL28	100	63.121	ENSSSCG00000040515	-	79	63.121	Sus_scrofa
ENSG00000108107	RPL28	99	89.706	ENSSSCG00000038865	-	84	74.194	Sus_scrofa
ENSG00000108107	RPL28	97	86.567	ENSTRUG00000025383	rpl28	100	79.562	Takifugu_rubripes
ENSG00000108107	RPL28	97	85.075	ENSTNIG00000002577	rpl28	100	79.562	Tetraodon_nigroviridis
ENSG00000108107	RPL28	100	99.270	ENSTTRG00000002428	RPL28	100	99.270	Tursiops_truncatus
ENSG00000108107	RPL28	88	73.333	ENSUAMG00000003339	-	94	73.333	Ursus_americanus
ENSG00000108107	RPL28	100	98.540	ENSUAMG00000017635	RPL28	100	98.540	Ursus_americanus
ENSG00000108107	RPL28	95	68.462	ENSUAMG00000002452	-	97	68.462	Ursus_americanus
ENSG00000108107	RPL28	98	61.194	ENSUAMG00000023977	-	81	61.194	Ursus_americanus
ENSG00000108107	RPL28	80	98.182	ENSUMAG00000024630	-	87	98.182	Ursus_maritimus
ENSG00000108107	RPL28	88	73.333	ENSUMAG00000006441	-	75	73.333	Ursus_maritimus
ENSG00000108107	RPL28	50	100.000	ENSVPAG00000004586	-	100	100.000	Vicugna_pacos
ENSG00000108107	RPL28	99	83.824	ENSXETG00000000132	rpl28	99	79.562	Xenopus_tropicalis
ENSG00000108107	RPL28	99	83.824	ENSXCOG00000001554	rpl28	100	77.372	Xiphophorus_couchianus
ENSG00000108107	RPL28	99	83.824	ENSXMAG00000005190	rpl28	100	78.102	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	-	TAS	Process
GO:0003723	RNA binding	22658674.	HDA	Function
GO:0003735	structural constituent of ribosome	12962325.	NAS	Function
GO:0005515	protein binding	20434207.21516116.25416956.26402096.	IPI	Function
GO:0005829	cytosol	-	TAS	Component
GO:0006412	translation	12962325.	NAS	Process
GO:0006413	translational initiation	-	TAS	Process
GO:0006614	SRP-dependent cotranslational protein targeting to membrane	-	TAS	Process
GO:0016020	membrane	19946888.	HDA	Component
GO:0019083	viral transcription	-	TAS	Process
GO:0022625	cytosolic large ribosomal subunit	12962325.	HDA	Component
GO:0022625	cytosolic large ribosomal subunit	21873635.	IBA	Component
GO:0030425	dendrite	15121898.	IDA	Component
GO:0036464	cytoplasmic ribonucleoprotein granule	15121898.	IDA	Component
GO:0044297	cell body	15121898.	IDA	Component
GO:0070062	extracellular exosome	20458337.	HDA	Component

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
BLCA	chr19	55386654	Missense_Mutation	novel	D56N	0.07	Ribosomal_L28e
BLCA	chr19	55386370	Missense_Mutation	NA	L5V	0.24	Ribosomal_L28e
BLCA	chr19	55387900	Intron	novel		0.35
BLCA	chr19	55388100	Intron	novel		0.25
BRCA	chr19	55386799	Intron	novel		0.57
BRCA	chr19	55387907	Intron	NA		0.12
CESC	chr19	55387890	Intron	novel		0.18
CESC	chr19	55391659	3'UTR	novel		0.38
CESC	chr19	55388341	3'UTR	novel		0.67
CESC	chr19	55388296	Silent	NA	V126V	0.26
CESC	chr19	55387210	Intron	novel		0.58
CESC	chr19	55386718	Intron	NA		0.32
CHOL	chr19	55388188	Intron	NA		0.35
COAD	chr19	55388037	Missense_Mutation	NA	D105N	0.43
COAD	chr19	55388087	Intron	novel		0.05
COAD	chr19	55387555	Intron	novel		0.4
COAD	chr19	55387086	Intron	novel		0.31
COAD	chr19	55388253	Missense_Mutation	NA	R112H	0.27
COAD	chr19	55387963	Missense_Mutation	NA	T80N	0.27
COAD	chr19	55386397	Missense_Mutation	NA	S14P	0.23	Ribosomal_L28e
COAD	chr19	55388327	Missense_Mutation	novel	S137P	0.19
ESCA	chr19	55387689	Intron	novel		0.5
ESCA	chr19	55388047	Missense_Mutation	novel	M108T	0.54
KIRP	chr19	55391389	3'UTR	novel		0.8
KIRP	chr19	55391818	3'UTR	novel		0.27
KIRP	chr19	55386568	Splice_Site	novel	X28_splice	0.28
LIHC	chr19	55387956	Missense_Mutation	novel	V78M	0.4
LIHC	chr19	55387048	Intron	novel		1
LIHC	chr19	55386910	Intron	novel		0.17
LUAD	chr19	55387961	Silent	NA	R79R	0.54
LUAD	chr19	55386658	Missense_Mutation	novel	G57D	0.14	Ribosomal_L28e
LUAD	chr19	55386411	Missense_Mutation	NA	I18M	0.14	Ribosomal_L28e
LUAD	chr19	55386714	Intron	novel		0.38
LUSC	chr19	55386614	Silent	novel	G42G	0.34
LUSC	chr19	55387960	Missense_Mutation	NA	R79L	0.37
LUSC	chr19	55387968	Missense_Mutation	rs750708696	I82V	0.24
OV	chr19	55388076	Intron	novel		0.32
PAAD	chr19	55387990	Missense_Mutation	rs150642428	T89M	0.04
PAAD	chr19	55388253	Missense_Mutation	NA	R112H	0.16
PRAD	chr19	55386682	Missense_Mutation	NA	K65M	0.29
PRAD	chr19	55388178	Intron	novel		0.63
READ	chr19	55391767	3'UTR	novel		0.24
READ	chr19	55388264	Missense_Mutation	rs745789187	A116T	0.21
READ	chr19	55387822	Intron	novel		0.33
READ	chr19	55386645	Missense_Mutation	NA	P53S	0.39	Ribosomal_L28e
SARC	chr19	55387862	Intron	novel		0.08
SARC	chr19	55386665	Silent	novel	G59G	0.38
SKCM	chr19	55386598	Missense_Mutation	novel	S37F	0.31	Ribosomal_L28e
SKCM	chr19	55387889	Intron	novel		0.42
SKCM	chr19	55387897	Intron	novel		0.26
STAD	chr19	55388032	Missense_Mutation	rs755058781	R103H	0.1
STAD	chr19	55387983	Missense_Mutation	rs755535252	R87C	0.14
UCEC	chr19	55391626	3'UTR	novel		0.49
UCEC	chr19	55388307	Missense_Mutation	rs762203967	R130Q	0.35
UCEC	chr19	55391527	3'UTR	rs147422393		0.21
UCEC	chr19	55387381	Intron	novel		0.08
UCEC	chr19	55387984	Missense_Mutation	novel	R87H	0.25
UCEC	chr19	55387943	Silent	NA	P73P	0.52
UCEC	chr19	55387460	Intron	novel		0.21
UCEC	chr19	55391522	3'UTR	novel		0.11
UCEC	chr19	55386421	Missense_Mutation	NA	K22E	0.29	Ribosomal_L28e
UCEC	chr19	55387288	Intron	novel		0.44
UCEC	chr19	55387915	Intron	novel		0.24
UCEC	chr19	55386688	Missense_Mutation	novel	R67K	0.58
UCEC	chr19	55391664	3'UTR	rs373129041		0.52
UCEC	chr19	55391597	3'UTR	NA		0.35
UCEC	chr19	55387679	Intron	novel		0.25
UCEC	chr19	55391564	3'UTR	NA		0.28
UCEC	chr19	55391752	3'UTR	novel		0.25
UCEC	chr19	55391560	3'UTR	novel		0.24
UCEC	chr19	55391665	3'UTR	novel		0.4
UCEC	chr19	55386692	Splice_Region	novel	S68S	0.3
UCEC	chr19	55388172	Intron	novel		0.19
UCEC	chr19	55387187	Intron	novel		0.34
UCEC	chr19	55388306	Missense_Mutation	rs773763514	R130W	0.36
UCEC	chr19	55386907	Intron	novel		0.22
UCEC	chr19	55387460	Intron	novel		0.43
UCEC	chr19	55387957	Missense_Mutation	novel	V78A	0.48
UCEC	chr19	55391700	3'UTR	novel		0.46

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
BLCA	AMP	0.3113	0.013691
BRCA	AMP	0.1889	0.0014488
CESC	DEL	0.0678	0.027508
DLBC	AMP	0.1667	0.017368
KIRP	DEL	0.0451	0.054726
LGG	DEL	0.5049	1.4433e-28
PAAD	DEL	0.0707	0.035089
PRAD	AMP	0.0325	0.17703
READ	DEL	0.103	0.23023
TGCT	DEL	0.2867	0.0046229
UCS	DEL	0.1607	0.12448

Survival Analysis

Cancer	P-value	Q-value
KIRC	0.0001	Kaplan-Meier Survival Analysis
SARC	0.015	Kaplan-Meier Survival Analysis
ACC	0.00043	Kaplan-Meier Survival Analysis
HNSC	0.043	Kaplan-Meier Survival Analysis
SKCM	0.028	Kaplan-Meier Survival Analysis
LUSC	0.037	Kaplan-Meier Survival Analysis
BRCA	0.013	Kaplan-Meier Survival Analysis
KIRP	0.011	Kaplan-Meier Survival Analysis
COAD	0.022	Kaplan-Meier Survival Analysis
BLCA	0.0051	Kaplan-Meier Survival Analysis
READ	0.043	Kaplan-Meier Survival Analysis
LIHC	0.014	Kaplan-Meier Survival Analysis
UVM	0.041	Kaplan-Meier Survival Analysis

Drugs

EuRBPDB

Description

RBDs

RBPome

Expression

Transcripts

Gene Model

Pathways

PPI

Orthologs

Gene Ontology

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742