EuRBPDB

Description

RBDs

RBPome

Literatures

Expression

Transcripts

Gene Model

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000108256 (Gene tree)
Gene ID: 57532
Gene Symbol: NUFIP2
Alias: KIAA1321|MGC117262|PIG1|182-FIP|FIP-82|82-FIP
Full Name: nuclear FMR1 interacting protein 2
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Minus strand
Length: 38,313 bases
Position: chr17:29,255,836-29,294,148
Accession: 17634
RBP type: canonical RBP
Summary: (Nuclear FMR1 Interacting Protein 2) is a Protein Coding gene. Diseases associated with NUFIP2 include Chromosome 17Q11.2 Deletion Syndrome, 1.4-Mb. Gene Ontology (GO) annotations related to this gene include RNA binding.

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000225388	NUFIP2	PF15293.6	5.4e-297	1	1
ENSP00000463450	NUFIP2	PF15293.6	3e-08	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
22681889	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts	4SURIC & HEK293	2012 May	Baltz AG	DOI: 10.1016/j.molcel.2012.05.021
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
29431736	Capturing the interactome of newly transcribed RNA	PolyT-RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	RIC & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
22658674	Insights into RNA biology from an atlas of mammalian mRNA-binding proteins	RIC & Hela	2012 May 31	Castello A	DOI: 10.1016/j.cell.2012.04.031
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
27453046	Comprehensive Identification of RNA-Binding Domains in Human Cells	RIC & Hela	2016 Aug 18	Castello A	DOI: 10.1016/j.molcel.2016.06.029
30352994	Discovery of RNA-binding proteins and characterization of their dynamic responses by enhanced RNA interactome capture	RIC & Jurkat	2018 Oct 23	Perez-Perri JI	DOI:10.1038/s41467-018-06557-8

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
15805463	Kissing complex RNAs mediate interaction between the Fragile-X mental retardation protein KH2 domain and brain polyribosomes.	Genes Dev	2005 Apr 15	Darnell JC	-
31289466	Role of caprin-1 in carcinogenesis.	Oncol Lett	2019 Jul	Yang ZS	doi: 10.3892/ol.2019.10295
19166269	A novel function for fragile X mental retardation protein in translational activation.	PLoS Biol	2009 Jan 20	Bechara EG	doi: 10.1371/journal.pbio.1000016.
17170008	Fragile X related protein 1 isoforms differentially modulate the affinity of fragile X mental retardation protein for G-quartet RNA structure.	Nucleic Acids Res	2007	Bechara E	-
20570707	The role of G-quadruplex in RNA metabolism: involvement of FMRP and FMR2P.	Biochimie	2010 Aug	Melko M	doi: 10.1016/j.biochi.2010.05.018
24462888	Fragile X Syndrome: from molecular pathology to therapy.	Neurosci Biobehav Rev	2014 Oct	Maurin T	doi: 10.1016/j.neubiorev.2014.01.006
29352114	Binding of NUFIP2 to Roquin promotes recognition and regulation of ICOS mRNA.	Nat Commun	2018 Jan 19	Rehage N	doi: 10.1038/s41467-017-02582-1.
16418001	RNA binding proteins and the regulation of neuronal synaptic plasticity.	Curr Opin Neurobiol	2006 Feb	Ule J	-
17923234	Analysis of mRNA translation in cultured hippocampal neurons.	Methods Enzymol	2007	Huang YS	-
26851502	Neuron class-specific requirements for Fragile X Mental Retardation Protein in critical period development of calcium signaling in learning and memory circuitry.	Neurobiol Dis	2016 May	Doll CA	doi: 10.1016/j.nbd.2016.02.006
10546896	Biology of the fragile X mental retardation protein, an RNA-binding protein.	Biochem Cell Biol	1999	Khandjian EW	-
10556305	A novel RNA-binding nuclear protein that interacts with the fragile X mental retardation (FMR1) protein.	Hum Mol Genet	1999 Dec	Bardoni B	-
9624140	Purified recombinant Fmrp exhibits selective RNA binding as an intrinsic property of the fragile X mental retardation protein.	J Biol Chem	1998 Jun 19	Brown V	-
9030614	Fragile X mental retardation protein: nucleocytoplasmic shuttling and association with somatodendritic ribosomes.	J Neurosci	1997 Mar 1	Feng Y	-
8895584	A nuclear role for the Fragile X mental retardation protein.	EMBO J	1996 Oct 1	Fridell RA	-
16636078	Methylation regulates the intracellular protein-protein and protein-RNA interactions of FMRP.	J Cell Sci	2006 May 1	Dolzhanskaya N	-
16571602	The nuclear microspherule protein 58 is a novel RNA-binding protein that interacts with fragile X mental retardation protein in polyribosomal mRNPs from neurons.	Hum Mol Genet	2006 May 1	Davidovic L	-
12950170	The N-terminus of the fragile X mental retardation protein contains a novel domain involved in dimerization and RNA binding.	Biochemistry	2003 Sep 9	Adinolfi S	-
12594214	The fragile X mental retardation protein FMRP binds elongation factor 1A mRNA and negatively regulates its translation in vivo.	J Biol Chem	2003 May 2	Sung YJ	-
16510718	Fragile X mental retardation protein shifts between polyribosomes and stress granules after neuronal injury by arsenite stress or in vivo hippocampal electrode insertion.	J Neurosci	2006 Mar 1	Kim SH	-
12417522	Trapping of messenger RNA by Fragile X Mental Retardation protein into cytoplasmic granules induces translation repression.	Hum Mol Genet	2002 Nov 15	Mazroui R	-
12378270	Methylation of the arginine-glycine-rich region in the fragile X mental retardation protein FMRP differentially affects RNA binding.	Cell Mol Biol Lett	2002	Denman RB	-
11440196	Subcellular localization of fragile X mental retardation protein with the I304N mutation in the RNA-binding domain in cultured hippocampal neurons.	Cell Mol Neurobiol	2001 Feb	Castren M	-
11039725	Sensory stimulation increases cortical expression of the fragile X mental retardation protein in vivo.	Brain Res Mol Brain Res	2000 Aug 14	Todd PK	-
16006558	Fragile X mental retardation protein (FMRP) binds specifically to the brain cytoplasmic RNAs BC1/BC200 via a novel RNA-binding motif.	J Biol Chem	2005 Sep 30	Zalfa F	-
15548614	Fragile X mental retardation protein is necessary for neurotransmitter-activated protein translation at synapses.	Proc Natl Acad Sci U S A	2004 Dec 14	Weiler IJ	-
15516998	RNA and microRNAs in fragile X mental retardation.	Nat Cell Biol	2004 Nov	Jin P	-
16809002	The RNA binding and transport proteins staufen and fragile X mental retardation protein are expressed by rat primary afferent neurons and localize to peripheral and central axons.	Neuroscience	2006 Sep 15	Price TJ	-
15317853	Fragile X mental retardation protein is associated with translating polyribosomes in neuronal cells.	J Neurosci	2004 Aug 18	Stefani G	-
15183715	The Drosophila fragile X-related gene regulates axoneme differentiation during spermatogenesis.	Dev Biol	2004 Jun 15	Zhang YQ	-
14532325	Fragile X Mental Retardation protein determinants required for its association with polyribosomal mRNPs.	Hum Mol Genet	2003 Dec 1	Mazroui R	-
23401597	Expression of fragile X mental retardation protein and Fmr1 mRNA during folliculogenesis in the rat.	Reproduction	2013 Apr 15	Ferder I	doi: 10.1530/REP-12-0305
23115170	Regulation of neuronal excitability by interaction of fragile X mental retardation protein with slack potassium channels.	J Neurosci	2012 Oct 31	Zhang Y	doi: 10.1523/JNEUROSCI.2162-12.2012.
20122915	Proteomic analysis reveals CCT is a target of Fragile X mental retardation protein regulation in Drosophila.	Dev Biol	2010 Apr 15	Monzo K	doi: 10.1016/j.ydbio.2010.01.028
19837168	Fragile X mental retardation protein control of neuronal mRNA metabolism: Insights into mRNA stability.	Mol Cell Neurosci	2010 Jan	De Rubeis S	doi: 10.1016/j.mcn.2009.09.013
19487368	Discrimination of common and unique RNA-binding activities among Fragile X mental retardation protein paralogs.	Hum Mol Genet	2009 Sep 1	Darnell JC	doi: 10.1093/hmg/ddp255
19214804	The fragile X mental retardation protein in circadian rhythmicity and memory consolidation.	Mol Neurobiol	2009 Apr	Gatto CL	doi: 10.1007/s12035-009-8057-0
19005212	Cells lacking the fragile X mental retardation protein (FMRP) have normal RISC activity but exhibit altered stress granule assembly.	Mol Biol Cell	2009 Jan	Didiot MC	doi: 10.1091/mbc.E08-07-0737
18936162	Fragile X mental retardation protein FMRP binds mRNAs in the nucleus.	Mol Cell Biol	2009 Jan	Kim M	doi: 10.1128/MCB.01377-08
22993428	Learning and memory deficits consequent to reduction of the fragile X mental retardation protein result from metabotropic glutamate receptor-mediated inhibition of cAMP signaling in Drosophila.	J Neurosci	2012 Sep 19	Kanellopoulos AK	-
18638539	Modest alterations in patterns of motor neuron dendrite morphology in the Fmr1 knockout mouse model for fragile X.	Int J Dev Neurosci	2008 Nov	Thomas CC	doi: 10.1016/j.ijdevneu.2008.06.003
22961479	Expression of microRNA machinery proteins in different types of chronic rhinosinusitis.	Laryngoscope	2012 Dec	Zhang YN	doi: 10.1002/lary.23517
18474609	S6K1 phosphorylates and regulates fragile X mental retardation protein (FMRP) with the neuronal protein synthesis-dependent mammalian target of rapamycin (mTOR) signaling cascade.	J Biol Chem	2008 Jul 4	Narayanan U	doi: 10.1074/jbc.C800055200
18272470	Metabotropic glutamate receptors and fragile x mental retardation protein: partners in translational regulation at the synapse.	Sci Signal	2008 Feb 5	Ronesi JA	doi: 10.1126/stke.15pe6.
18184799	On BC1 RNA and the fragile X mental retardation protein.	Proc Natl Acad Sci U S A	2008 Jan 15	Iacoangeli A	doi: 10.1073/pnas.0710991105
17978095	Dynamic association of the fragile X mental retardation protein as a messenger ribonucleoprotein between microtubules and polyribosomes.	Mol Biol Cell	2008 Jan	Wang H	-
17881561	Fragile X mental retardation protein deficiency leads to excessive mGluR5-dependent internalization of AMPA receptors.	Proc Natl Acad Sci U S A	2007 Sep 25	Nakamoto M	-
17417632	A new function for the fragile X mental retardation protein in regulation of PSD-95 mRNA stability.	Nat Neurosci	2007 May	Zalfa F	-
17376973	Fragile X mental retardation protein induces synapse loss through acute postsynaptic translational regulation.	J Neurosci	2007 Mar 21	Pfeiffer BE	-
17132937	Lost once, the Fragile X Mental Retardation protein is now back onto brain polyribosomes.	RNA Biol	2005 Jan	Davidovic L	-
22737234	Fragile X mental retardation protein interacts with the RNA-binding protein Caprin1 in neuronal RiboNucleoProtein complexes [corrected].	PLoS One	2012	El Fatimy R	doi: 10.1371/journal.pone.0039338
22539853	Evidence for a fragile X mental retardation protein-mediated translational switch in metabotropic glutamate receptor-triggered Arc translation and long-term depression.	J Neurosci	2012 Apr 25	Niere F	doi: 10.1523/JNEUROSCI.4650-11.2012.
23313071	Linking the Fragile X mental retardation protein to the lipoxygenase pathway.	Med Hypotheses	2013 Mar	Beaulieu MA	doi: 10.1016/j.mehy.2012.11.046
21772992	Conformational-dependent and independent RNA binding to the fragile x mental retardation protein.	J Nucleic Acids	2011	Yan X	doi: 10.4061/2011/246127
21404421	Heads-up: new roles for the fragile X mental retardation protein in neural stem and progenitor cells.	Genesis	2011 Jun	Callan MA	doi: 10.1002/dvg.20745
21307257	Fragile X mental retardation protein regulates new neuron differentiation in the adult olfactory bulb.	J Neurosci	2011 Feb 9	Scotto-Lomassese S	doi: 10.1523/JNEUROSCI.5514-10.2011.
20713728	Altered mRNA transport, docking, and protein translation in neurons lacking fragile X mental retardation protein.	Proc Natl Acad Sci U S A	2010 Aug 31	Kao DI	doi: 10.1073/pnas.1010564107
20685971	Fragile X mental retardation protein is required for rapid experience-dependent regulation of the potassium channel Kv3.1b.	J Neurosci	2010 Aug 4	Strumbos JG	doi: 10.1523/JNEUROSCI.1125-10.2010.
20691595	Bicaudal-D regulates fragile X mental retardation protein levels, motility, and function during neuronal morphogenesis.	Curr Biol	2010 Aug 24	Bianco A	doi: 10.1016/j.cub.2010.07.016
20512134	Fragile X mental retardation protein controls gating of the sodium-activated potassium channel Slack.	Nat Neurosci	2010 Jul	Brown MR	doi: 10.1038/nn.2563
20457613	Roles of fragile X mental retardation protein in dopaminergic stimulation-induced synapse-associated protein synthesis and subsequent alpha-amino-3-hydroxyl-5-methyl-4-isoxazole-4-propionate (AMPA) receptor internalization.	J Biol Chem	2010 Jul 9	Wang H	doi: 10.1074/jbc.M110.116293
20463240	Short- and long-term memory are modulated by multiple isoforms of the fragile X mental retardation protein.	J Neurosci	2010 May 12	Banerjee P	doi: 10.1523/JNEUROSCI.6369-09.2010.
20434996	Fragile X mental retardation protein is required for synapse elimination by the activity-dependent transcription factor MEF2.	Neuron	2010 Apr 29	Pfeiffer BE	doi: 10.1016/j.neuron.2010.03.017.
28257890	A novel role of fragile X mental retardation protein in pre-mRNA alternative splicing through RNA-binding protein 14.	Neuroscience	2017 May 4	Zhou LT	doi: 10.1016/j.neuroscience.2017.02.044
25681562	Fragile X mental retardation protein (FMRP) interacting proteins exhibit different expression patterns during development.	Int J Dev Neurosci	2015 May	Bonaccorso CM	doi: 10.1016/j.ijdevneu.2015.02.004
25701550	Fragile X mental retardation protein: A paradigm for translational control by RNA-binding proteins.	Biochimie	2015 Jul	Chen E	doi: 10.1016/j.biochi.2015.02.005
25250047	Low-normal FMR1 CGG repeat length: phenotypic associations.	Front Genet	2014 Sep 9	Mailick MR	doi: 10.3389/fgene.2014.00309
25215498	SnapShot: FMRP mRNA targets and diseases.	Cell	2014 Sep 11	Pasciuto E	doi: 10.1016/j.cell.2014.08.035.
24811383	Fragile X mental retardation protein regulates synaptic and behavioral plasticity to repeated cocaine administration.	Neuron	2014 May 7	Smith LN	doi: 10.1016/j.neuron.2014.03.028.
24175909	Myosin Va is required for the transport of fragile X mental retardation protein (FMRP) granules.	Biol Cell	2014 Feb	Lindsay AJ	doi: 10.1111/boc.201200076
27462983	Tracking the Fragile X Mental Retardation Protein in a Highly Ordered Neuronal RiboNucleoParticles Population: A Link between Stalled Polyribosomes and RNA Granules.	PLoS Genet	2016 Jul 27	El Fatimy R	doi: 10.1371/journal.pgen.1006192
26719241	Fragile X Mental Retardation Protein expression in the retina is regulated by light.	Exp Eye Res	2016 May	Guimaraes-Souza EM	doi: 10.1016/j.exer.2015.11.025
26020477	GABAB receptor upregulates fragile X mental retardation protein expression in neurons.	Sci Rep	2015 May 28	Zhang W	doi: 10.1038/srep10468.
25908854	The Drosophila fragile X mental retardation protein participates in the piRNA pathway.	J Cell Sci	2015 Jun 1	Bozzetti MP	doi: 10.1242/jcs.161810
25917509	Fragile X mental retardation protein regulates olfactory sensitivity but not odorant discrimination.	Chem Senses	2015 Jun	Schilit Nitenson A	doi: 10.1093/chemse/bjv019
27829268	Altered Translational Control of Fragile X Mental Retardation Protein on Myelin Proteins in Neuropsychiatric Disorders.	Biomol Ther (Seoul)	2017 May 1	Jeon SJ	doi: 10.4062/biomolther.2016.042.
28685837	Proteomic analyses of nucleus laminaris identified candidate targets of the fragile X mental retardation protein.	J Comp Neurol	2017 Oct 15	Sakano H	doi: 10.1002/cne.24281
29668986	HITS-CLIP in various brain areas reveals new targets and new modalities of RNA binding by fragile X mental retardation protein.	Nucleic Acids Res	2018 Jul 6	Maurin T	doi: 10.1093/nar/gky267.
30107516	Fragile X mental retardation protein modulates the stability of its m6A-marked messenger RNA targets.	Hum Mol Genet	2018 Nov 15	Zhang F	doi: 10.1093/hmg/ddy292.
30240639	Fragile X mental retardation protein regulates accumulation of the active zone protein Munc18-1 in presynapses via local translation in axons during synaptogenesis.	Neurosci Res	2019 Sep	Parvin S	doi: 10.1016/j.neures.2018.09.013
30893603	Widespread Alterations in Translation Elongation in the Brain of Juvenile Fmr1 Knockout Mice.	Cell Rep	2019 Mar 19	Das Sharma S	doi: 10.1016/j.celrep.2019.02.086.
31118285	Kinase pathway inhibition restores PSD95 induction in neurons lacking fragile X mental retardation protein.	Proc Natl Acad Sci U S A	2019 Jun 11	Yang Y	doi: 10.1073/pnas.1812056116
15659339	Mechanisms of translational control by the 3' UTR in development and differentiation.	Semin Cell Dev Biol	2005 Feb	de Moor CH	-
19396385	Fragile X mental retardation protein recognition of G quadruplex structure per se is sufficient for high affinity binding to RNA.	Mol Biosyst	2008 Dec	Bole M	doi: 10.1039/b812537f

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000225388	NUFIP2-201	10850	XM_017024896	ENSP00000225388	695 (aa)	XP_016880385	Q7Z417
ENST00000579665	NUFIP2-202	559	-	ENSP00000463450	120 (aa)	-	Q7Z417

Gene Model

Click here to download ENSG00000108256's gene model file

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000108256	Body Mass Index	7.65346517690446E-5	17903300
ENSG00000108256	Cholesterol, HDL	4.75951132718611E-7	17903299

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000108256	rs8614	17	29261788	A	Headache	29397368	[0.007-0.014] unit increase	0.0105	HP_0002315
ENSG00000108256	rs8614	17	29261788	A	Self-reported math ability (MTAG)	30038396	[0.0085-0.0175] unit decrease	0.013	EFO_0004875
ENSG00000108256	rs8614	17	29261788	A	Highest math class taken (MTAG)	30038396	[0.0093-0.0175] unit decrease	0.0134	EFO_0004875
ENSG00000108256	rs3785961	17	29264307	?	Adolescent idiopathic scoliosis	30019117			EFO_0005423
ENSG00000108256	rs62065197	17	29266624	?	Red cell distribution width	30595370			EFO_0005192
ENSG00000108256	rs8614	17	29261788	A	Smoking initiation (ever regular vs never regular) (MTAG)	30643251	[0.0063-0.0117] unit increase	0.00898031	EFO_0006527

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000108256's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000108256	NUFIP2	97	96.429	ENSAMEG00000004332	NUFIP2	95	95.606	Ailuropoda_melanoleuca
ENSG00000108256	NUFIP2	88	56.474	ENSACAG00000012887	NUFIP2	87	56.563	Anolis_carolinensis
ENSG00000108256	NUFIP2	100	100.000	ENSANAG00000037766	NUFIP2	100	100.000	Aotus_nancymaae
ENSG00000108256	NUFIP2	91	95.411	ENSBTAG00000033077	NUFIP2	91	95.411	Bos_taurus
ENSG00000108256	NUFIP2	100	100.000	ENSCJAG00000013508	NUFIP2	100	100.000	Callithrix_jacchus
ENSG00000108256	NUFIP2	100	96.429	ENSCAFG00000018888	NUFIP2	94	94.545	Canis_familiaris
ENSG00000108256	NUFIP2	100	96.429	ENSCAFG00020011598	NUFIP2	94	94.545	Canis_lupus_dingo
ENSG00000108256	NUFIP2	100	97.826	ENSCHIG00000015671	NUFIP2	100	95.252	Capra_hircus
ENSG00000108256	NUFIP2	100	100.000	ENSTSYG00000030053	NUFIP2	100	100.000	Carlito_syrichta
ENSG00000108256	NUFIP2	61	93.333	ENSCAPG00000012965	NUFIP2	100	93.333	Cavia_aperea
ENSG00000108256	NUFIP2	100	89.353	ENSCPOG00000002815	NUFIP2	100	89.353	Cavia_porcellus
ENSG00000108256	NUFIP2	100	100.000	ENSCCAG00000024630	NUFIP2	100	100.000	Cebus_capucinus
ENSG00000108256	NUFIP2	100	100.000	ENSCATG00000031290	NUFIP2	100	100.000	Cercocebus_atys
ENSG00000108256	NUFIP2	100	100.000	ENSCLAG00000007711	NUFIP2	100	95.108	Chinchilla_lanigera
ENSG00000108256	NUFIP2	100	100.000	ENSCSAG00000007009	NUFIP2	100	99.137	Chlorocebus_sabaeus
ENSG00000108256	NUFIP2	100	96.429	ENSCHOG00000002740	-	64	95.270	Choloepus_hoffmanni
ENSG00000108256	NUFIP2	100	100.000	ENSCHOG00000003393	-	95	93.333	Choloepus_hoffmanni
ENSG00000108256	NUFIP2	89	81.059	ENSCPBG00000020115	NUFIP2	97	78.733	Chrysemys_picta_bellii
ENSG00000108256	NUFIP2	100	100.000	ENSCANG00000019856	NUFIP2	100	100.000	Colobus_angolensis_palliatus
ENSG00000108256	NUFIP2	100	100.000	ENSCGRG00001019451	Nufip2	94	93.636	Cricetulus_griseus_chok1gshd
ENSG00000108256	NUFIP2	86	89.465	ENSCGRG00000011209	-	96	89.465	Cricetulus_griseus_crigri
ENSG00000108256	NUFIP2	91	90.032	ENSCGRG00000001173	-	93	90.032	Cricetulus_griseus_crigri
ENSG00000108256	NUFIP2	93	94.574	ENSDNOG00000014525	NUFIP2	92	94.242	Dasypus_novemcinctus
ENSG00000108256	NUFIP2	92	94.237	ENSDORG00000023937	Nufip2	95	94.246	Dipodomys_ordii
ENSG00000108256	NUFIP2	93	90.358	ENSETEG00000003312	NUFIP2	94	90.202	Echinops_telfairi
ENSG00000108256	NUFIP2	100	98.913	ENSEASG00005009801	NUFIP2	100	96.403	Equus_asinus_asinus
ENSG00000108256	NUFIP2	100	97.849	ENSECAG00000004975	NUFIP2	100	96.408	Equus_caballus
ENSG00000108256	NUFIP2	87	88.704	ENSEEUG00000008482	NUFIP2	100	88.704	Erinaceus_europaeus
ENSG00000108256	NUFIP2	98	82.143	ENSFCAG00000039498	-	95	73.282	Felis_catus
ENSG00000108256	NUFIP2	100	97.826	ENSFCAG00000007193	-	100	97.826	Felis_catus
ENSG00000108256	NUFIP2	87	79.174	ENSFALG00000006268	NUFIP2	92	79.008	Ficedula_albicollis
ENSG00000108256	NUFIP2	100	100.000	ENSFDAG00000010640	NUFIP2	100	94.388	Fukomys_damarensis
ENSG00000108256	NUFIP2	90	67.727	ENSGALG00000004042	NUFIP2	94	68.045	Gallus_gallus
ENSG00000108256	NUFIP2	100	100.000	ENSGGOG00000008590	NUFIP2	100	100.000	Gorilla_gorilla
ENSG00000108256	NUFIP2	100	100.000	ENSHGLG00000006811	-	100	94.532	Heterocephalus_glaber_female
ENSG00000108256	NUFIP2	98	86.283	ENSHGLG00000005730	-	96	86.187	Heterocephalus_glaber_female
ENSG00000108256	NUFIP2	98	86.136	ENSHGLG00100009259	-	96	86.043	Heterocephalus_glaber_male
ENSG00000108256	NUFIP2	100	100.000	ENSHGLG00100018426	-	95	94.545	Heterocephalus_glaber_male
ENSG00000108256	NUFIP2	92	85.826	ENSSTOG00000022663	-	98	83.036	Ictidomys_tridecemlineatus
ENSG00000108256	NUFIP2	100	100.000	ENSSTOG00000003701	-	95	95.909	Ictidomys_tridecemlineatus
ENSG00000108256	NUFIP2	91	91.139	ENSJJAG00000020851	-	92	90.506	Jaculus_jaculus
ENSG00000108256	NUFIP2	95	80.152	ENSJJAG00000022944	-	94	79.576	Jaculus_jaculus
ENSG00000108256	NUFIP2	90	64.297	ENSLACG00000012838	NUFIP2	97	63.020	Latimeria_chalumnae
ENSG00000108256	NUFIP2	93	94.401	ENSLAFG00000012294	NUFIP2	99	94.182	Loxodonta_africana
ENSG00000108256	NUFIP2	100	100.000	ENSMFAG00000040845	NUFIP2	100	100.000	Macaca_fascicularis
ENSG00000108256	NUFIP2	100	100.000	ENSMMUG00000012856	NUFIP2	100	100.000	Macaca_mulatta
ENSG00000108256	NUFIP2	100	100.000	ENSMNEG00000038891	NUFIP2	100	100.000	Macaca_nemestrina
ENSG00000108256	NUFIP2	100	100.000	ENSMLEG00000036478	NUFIP2	100	100.000	Mandrillus_leucophaeus
ENSG00000108256	NUFIP2	87	71.782	ENSMGAG00000005925	NUFIP2	100	72.442	Meleagris_gallopavo
ENSG00000108256	NUFIP2	87	92.359	ENSMAUG00000005650	Nufip2	100	92.359	Mesocricetus_auratus
ENSG00000108256	NUFIP2	100	100.000	ENSMICG00000016380	NUFIP2	100	100.000	Microcebus_murinus
ENSG00000108256	NUFIP2	100	100.000	ENSMOCG00000022086	Nufip2	95	93.788	Microtus_ochrogaster
ENSG00000108256	NUFIP2	89	83.037	ENSMODG00000019327	NUFIP2	84	83.333	Monodelphis_domestica
ENSG00000108256	NUFIP2	100	100.000	ENSMUSG00000037857	Nufip2	95	93.333	Mus_musculus
ENSG00000108256	NUFIP2	100	100.000	MGP_SPRETEiJ_G0017622	Nufip2	95	88.252	Mus_spretus
ENSG00000108256	NUFIP2	92	80.835	ENSMPUG00000014002	NUFIP2	94	80.835	Mustela_putorius_furo
ENSG00000108256	NUFIP2	100	96.774	ENSMLUG00000016685	NUFIP2	100	96.774	Myotis_lucifugus
ENSG00000108256	NUFIP2	90	73.642	ENSNGAG00000018948	-	94	73.642	Nannospalax_galili
ENSG00000108256	NUFIP2	100	96.429	ENSNGAG00000016940	-	94	93.636	Nannospalax_galili
ENSG00000108256	NUFIP2	100	100.000	ENSNLEG00000003299	NUFIP2	100	100.000	Nomascus_leucogenys
ENSG00000108256	NUFIP2	91	86.772	ENSNLEG00000006740	-	91	86.820	Nomascus_leucogenys
ENSG00000108256	NUFIP2	59	80.630	ENSMEUG00000016377	-	59	79.903	Notamacropus_eugenii
ENSG00000108256	NUFIP2	100	100.000	ENSOPRG00000011583	NUFIP2	95	95.159	Ochotona_princeps
ENSG00000108256	NUFIP2	100	100.000	ENSODEG00000009679	NUFIP2	100	94.245	Octodon_degus
ENSG00000108256	NUFIP2	100	96.429	ENSOANG00000012647	NUFIP2	94	78.614	Ornithorhynchus_anatinus
ENSG00000108256	NUFIP2	100	100.000	ENSOCUG00000016483	NUFIP2	95	95.909	Oryctolagus_cuniculus
ENSG00000108256	NUFIP2	100	96.809	ENSOGAG00000007400	NUFIP2	95	95.000	Otolemur_garnettii
ENSG00000108256	NUFIP2	100	96.429	ENSOARG00000006644	NUFIP2	96	95.303	Ovis_aries
ENSG00000108256	NUFIP2	100	100.000	ENSPPAG00000030125	NUFIP2	100	100.000	Pan_paniscus
ENSG00000108256	NUFIP2	87	95.349	ENSPPRG00000003571	NUFIP2	99	92.663	Panthera_pardus
ENSG00000108256	NUFIP2	87	95.349	ENSPTIG00000017161	NUFIP2	87	95.349	Panthera_tigris_altaica
ENSG00000108256	NUFIP2	100	100.000	ENSPTRG00000008947	NUFIP2	100	100.000	Pan_troglodytes
ENSG00000108256	NUFIP2	100	100.000	ENSPANG00000023299	NUFIP2	100	100.000	Papio_anubis
ENSG00000108256	NUFIP2	77	77.239	ENSPSIG00000004369	NUFIP2	100	77.425	Pelodiscus_sinensis
ENSG00000108256	NUFIP2	100	100.000	ENSPEMG00000011656	Nufip2	95	94.242	Peromyscus_maniculatus_bairdii
ENSG00000108256	NUFIP2	91	84.044	ENSPCIG00000014922	NUFIP2	90	82.175	Phascolarctos_cinereus
ENSG00000108256	NUFIP2	100	100.000	ENSPPYG00000008121	NUFIP2	100	99.424	Pongo_abelii
ENSG00000108256	NUFIP2	99	95.699	ENSPCAG00000006342	NUFIP2	79	93.117	Procavia_capensis
ENSG00000108256	NUFIP2	100	100.000	ENSPCOG00000017278	NUFIP2	100	100.000	Propithecus_coquereli
ENSG00000108256	NUFIP2	100	96.429	ENSPVAG00000012645	NUFIP2	95	95.000	Pteropus_vampyrus
ENSG00000108256	NUFIP2	95	90.332	ENSRNOG00000008382	AABR07046727.1	98	89.879	Rattus_norvegicus
ENSG00000108256	NUFIP2	100	100.000	ENSRNOG00000024964	Nufip2	100	93.525	Rattus_norvegicus
ENSG00000108256	NUFIP2	100	100.000	ENSRBIG00000032631	NUFIP2	100	100.000	Rhinopithecus_bieti
ENSG00000108256	NUFIP2	100	100.000	ENSRROG00000042054	NUFIP2	100	100.000	Rhinopithecus_roxellana
ENSG00000108256	NUFIP2	100	100.000	ENSSBOG00000036071	-	100	100.000	Saimiri_boliviensis_boliviensis
ENSG00000108256	NUFIP2	95	96.552	ENSSBOG00000031116	-	100	86.735	Saimiri_boliviensis_boliviensis
ENSG00000108256	NUFIP2	87	84.793	ENSSHAG00000016442	NUFIP2	99	84.793	Sarcophilus_harrisii
ENSG00000108256	NUFIP2	58	88.353	ENSSARG00000007216	-	57	88.353	Sorex_araneus
ENSG00000108256	NUFIP2	87	70.936	ENSSPUG00000005093	NUFIP2	100	71.100	Sphenodon_punctatus
ENSG00000108256	NUFIP2	100	96.429	ENSSSCG00000017785	NUFIP2	94	94.713	Sus_scrofa
ENSG00000108256	NUFIP2	87	79.669	ENSTGUG00000006298	NUFIP2	100	79.669	Taeniopygia_guttata
ENSG00000108256	NUFIP2	87	94.020	ENSTBEG00000008374	NUFIP2	100	94.020	Tupaia_belangeri
ENSG00000108256	NUFIP2	87	91.030	ENSTTRG00000016328	NUFIP2	87	91.030	Tursiops_truncatus
ENSG00000108256	NUFIP2	87	95.688	ENSUAMG00000014575	NUFIP2	95	95.688	Ursus_americanus
ENSG00000108256	NUFIP2	89	95.624	ENSUMAG00000010751	NUFIP2	93	95.624	Ursus_maritimus
ENSG00000108256	NUFIP2	100	96.429	ENSVVUG00000020998	NUFIP2	94	94.394	Vulpes_vulpes
ENSG00000108256	NUFIP2	80	91.667	ENSXETG00000009447	nufip2	96	55.951	Xenopus_tropicalis

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0003723	RNA binding	22658674.22681889.	HDA	Function
GO:0003723	RNA binding	12837692.	IDA	Function
GO:0005515	protein binding	12837692.16407062.25416956.26184334.	IPI	Function
GO:0005634	nucleus	12837692.26184334.	IDA	Component
GO:0005654	nucleoplasm	-	IDA	Component
GO:0005737	cytoplasm	12837692.26184334.	IDA	Component
GO:0005829	cytosol	-	IDA	Component
GO:0010494	cytoplasmic stress granule	26184334.	IDA	Component
GO:0016020	membrane	19946888.	HDA	Component
GO:0016604	nuclear body	-	IDA	Component
GO:0042788	polysomal ribosome	12837692.	IDA	Component