EuRBPDB

Description

Ensembl ID: ENSG00000108528 (Gene tree)
Gene ID: 8402
Gene Symbol: SLC25A11
Alias: OGC|SLC20A4
Full Name: solute carrier family 25 member 11
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Minus strand
Length: 3,122 bases
Position: chr17:4,937,130-4,940,251
Accession: 10981
RBP type: non-canonical RBP
Summary: The oxoglutarate/malate carrier transports 2-oxoglutarate across the inner membranes of mitochondria in an electroneutral exchange for malate or other dicarboxylic acids (summary by Iacobazzi et al., 1992 [PubMed 1457818]).[supplied by OMIM, Jan 2011]

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
22681889	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts	4SURIC & HEK293	2012 May	Baltz AG	DOI: 10.1016/j.molcel.2012.05.021
29431736	Capturing the interactome of newly transcribed RNA	RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000544061	SLC25A11-202	952	-	ENSP00000440804	263 (aa)	-	Q02978
ENST00000574710	SLC25A11-204	2176	-	-	- (aa)	-	-
ENST00000225665	SLC25A11-201	1897	XM_024450994	ENSP00000225665	314 (aa)	XP_024306762	Q02978
ENST00000576951	SLC25A11-205	893	-	ENSP00000458993	296 (aa)	-	I3L1P8
ENST00000570543	SLC25A11-203	322	-	-	- (aa)	-	-

Gene Model

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000108528	Platelet Function Tests	3.6051800E-005	-

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000108528	rs1060431	17	4937573	A	Platelet count	27863252	[0.05-0.077] unit increase	0.0636259	EFO_0004309
ENSG00000108528	rs1060431	17	4937573	A	Platelet distribution width	27863252	[0.06-0.087] unit decrease	0.07337288	EFO_0007984
ENSG00000108528	rs1060431	17	4937573	A	Plateletcrit	27863252	[0.036-0.064] unit increase	0.04995122	EFO_0007985

Protein-Protein Interaction (PPI)

* RBP PPI network refers to all genes directly bind to RBP

Orthologs identified by RBPome

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000108528	SLC25A11	100	96.497	ENSMUSG00000014606	Slc25a11	100	97.368	Mus_musculus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0003723	RNA binding	22681889.	HDA	Function
GO:0005634	nucleus	21630459.	HDA	Component
GO:0005739	mitochondrion	20833797.	HDA	Component
GO:0005743	mitochondrial inner membrane	-	TAS	Component
GO:0005887	integral component of plasma membrane	1457818.	TAS	Component
GO:0006094	gluconeogenesis	-	TAS	Process
GO:0015367	oxoglutarate:malate antiporter activity	21873635.	IBA	Function
GO:0015742	alpha-ketoglutarate transport	-	IEA	Process
GO:0055085	transmembrane transport	-	IEA	Process