EuRBPDB

Description

Ensembl ID: ENSG00000108588 (Gene tree)
Gene ID: 57003
Gene Symbol: CCDC47
Alias: GK001
Full Name: coiled-coil domain containing 47
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Minus strand
Length: 31,102 bases
Position: chr17:63,745,250-63,776,351
Accession: 24856
RBP type: non-canonical RBP
Summary: (Coiled-Coil Domain Containing 47) is a Protein Coding gene. Diseases associated with CCDC47 include Trichohepatoneurodevelopmental Syndrome. Gene Ontology (GO) annotations related to this gene include calcium ion binding.

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
22658674	Insights into RNA biology from an atlas of mammalian mRNA-binding proteins	RIC & Hela	2012 May 31	Castello A	DOI: 10.1016/j.cell.2012.04.031
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000403162	CCDC47-202	2195	XM_005257527	ENSP00000384888	483 (aa)	XP_005257584	Q96A33
ENST00000582331	CCDC47-205	693	-	-	- (aa)	-	-
ENST00000225726	CCDC47-201	3466	-	ENSP00000225726	483 (aa)	-	Q96A33
ENST00000582252	CCDC47-204	1719	-	ENSP00000463577	480 (aa)	-	Q96A33
ENST00000612558	CCDC47-207	1586	-	ENSP00000482148	190 (aa)	-	A0A087WYW6
ENST00000580986	CCDC47-203	552	-	ENSP00000462202	19 (aa)	-	J3KRX4
ENST00000584112	CCDC47-206	588	-	-	- (aa)	-	-

Gene Model

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000108588	rs7212196	17	63757621	T	Self-reported math ability (MTAG)	30038396	[0.0068-0.0138] unit decrease	0.0103	EFO_0004875

Protein-Protein Interaction (PPI)

Orthologs identified by RBPome

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000108588	CCDC47	100	97.930	ENSMUSG00000078622	Ccdc47	100	99.401	Mus_musculus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0001649	osteoblast differentiation	16210410.	HDA	Process
GO:0003723	RNA binding	22658674.	HDA	Function
GO:0005509	calcium ion binding	21873635.	IBA	Function
GO:0005515	protein binding	21903422.	IPI	Function
GO:0005783	endoplasmic reticulum	21873635.	IBA	Component
GO:0005783	endoplasmic reticulum	-	IDA	Component
GO:0005791	rough endoplasmic reticulum	-	IEA	Component
GO:0006983	ER overload response	-	IEA	Process
GO:0007029	endoplasmic reticulum organization	-	IEA	Process
GO:0009791	post-embryonic development	-	IEA	Process
GO:0016020	membrane	16210410.19946888.	HDA	Component
GO:0016021	integral component of membrane	-	IEA	Component
GO:0030433	ubiquitin-dependent ERAD pathway	-	IEA	Process
GO:0055074	calcium ion homeostasis	-	IEA	Process