EuRBPDB

Description

RBDs

RBPome

Expression

Transcripts

Gene Model

Pathways

Phenotypes

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000108651 (Gene tree)
Gene ID: 55813
Gene Symbol: UTP6
Alias: HCA66|C17orf40
Full Name: UTP6 small subunit processome component
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Minus strand
Length: 40,867 bases
Position: chr17:31,860,899-31,901,765
Accession: 18279
RBP type: canonical RBP
Summary: (UTP6 Small Subunit Processome Component) is a Protein Coding gene. Diseases associated with UTP6 include Chromosome 17Q11.2 Deletion Syndrome, 1.4-Mb and Interstitial Keratitis. Among its related pathways are rRNA processing in the nucleus and cytosol and Gene Expression. Gene Ontology (GO) annotations related to this gene include snoRNA binding.

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000261708	U3_assoc_6	PF08640.11	1.4e-24	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
29431736	Capturing the interactome of newly transcribed RNA	PolyT-RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30352994	Discovery of RNA-binding proteins and characterization of their dynamic responses by enhanced RNA interactome capture	RIC & Jurkat	2018 Oct 23	Perez-Perri JI	DOI:10.1038/s41467-018-06557-8

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000579878	UTP6-207	582	-	-	- (aa)	-	-
ENST00000477128	UTP6-202	2344	-	-	- (aa)	-	-
ENST00000583408	UTP6-209	1440	-	-	- (aa)	-	-
ENST00000261708	UTP6-201	4392	XM_005258012	ENSP00000261708	597 (aa)	XP_005258069	Q9NYH9
ENST00000477860	UTP6-203	476	-	-	- (aa)	-	-
ENST00000484661	UTP6-204	694	-	-	- (aa)	-	-
ENST00000579459	UTP6-206	410	-	ENSP00000464599	29 (aa)	-	J3QSA7
ENST00000581012	UTP6-208	563	-	ENSP00000462135	61 (aa)	-	J3KRR8
ENST00000490218	UTP6-205	807	-	-	- (aa)	-	-

Gene Model

Click here to download ENSG00000108651's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa03008	Ribosome biogenesis in eukaryotes	KEGG

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000108651	Fibrinogen	1.9190000E-005	-

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000108651's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000108651	UTP6	100	56.281	ENSAPOG00000000435	utp6	100	56.281	Acanthochromis_polyacanthus
ENSG00000108651	UTP6	99	87.919	ENSAMEG00000005443	UTP6	99	87.919	Ailuropoda_melanoleuca
ENSG00000108651	UTP6	100	54.439	ENSACIG00000004124	utp6	100	54.439	Amphilophus_citrinellus
ENSG00000108651	UTP6	100	55.946	ENSAOCG00000016812	utp6	100	55.946	Amphiprion_ocellaris
ENSG00000108651	UTP6	100	55.946	ENSAPEG00000023565	utp6	100	55.946	Amphiprion_percula
ENSG00000108651	UTP6	100	56.616	ENSATEG00000003401	utp6	100	56.616	Anabas_testudineus
ENSG00000108651	UTP6	99	65.365	ENSAPLG00000005821	UTP6	99	65.365	Anas_platyrhynchos
ENSG00000108651	UTP6	100	64.657	ENSACAG00000009472	UTP6	100	64.657	Anolis_carolinensis
ENSG00000108651	UTP6	100	95.645	ENSANAG00000034603	UTP6	100	95.645	Aotus_nancymaae
ENSG00000108651	UTP6	100	57.119	ENSACLG00000006728	utp6	100	57.119	Astatotilapia_calliptera
ENSG00000108651	UTP6	100	56.281	ENSAMXG00000009478	utp6	100	56.281	Astyanax_mexicanus
ENSG00000108651	UTP6	100	73.411	ENSBTAG00000003769	-	98	73.658	Bos_taurus
ENSG00000108651	UTP6	100	74.749	ENSBTAG00000015612	UTP6	100	74.749	Bos_taurus
ENSG00000108651	UTP6	100	95.645	ENSCJAG00000014115	UTP6	100	95.645	Callithrix_jacchus
ENSG00000108651	UTP6	100	89.465	ENSCAFG00000018507	UTP6	100	89.465	Canis_familiaris
ENSG00000108651	UTP6	100	89.465	ENSCAFG00020014678	UTP6	100	89.465	Canis_lupus_dingo
ENSG00000108651	UTP6	100	75.084	ENSCHIG00000017954	-	100	75.084	Capra_hircus
ENSG00000108651	UTP6	100	74.916	ENSCHIG00000009726	-	100	74.916	Capra_hircus
ENSG00000108651	UTP6	99	80.402	ENSTSYG00000002202	UTP6	99	80.402	Carlito_syrichta
ENSG00000108651	UTP6	69	95.000	ENSCAPG00000017595	UTP6	98	73.432	Cavia_aperea
ENSG00000108651	UTP6	99	86.409	ENSCPOG00000014294	UTP6	100	86.409	Cavia_porcellus
ENSG00000108651	UTP6	100	88.945	ENSCCAG00000033318	-	100	88.945	Cebus_capucinus
ENSG00000108651	UTP6	100	97.492	ENSCATG00000034868	UTP6	100	97.492	Cercocebus_atys
ENSG00000108651	UTP6	99	87.584	ENSCLAG00000007274	UTP6	99	87.584	Chinchilla_lanigera
ENSG00000108651	UTP6	100	96.990	ENSCSAG00000006595	UTP6	100	96.990	Chlorocebus_sabaeus
ENSG00000108651	UTP6	76	100.000	ENSCHOG00000010940	-	88	67.754	Choloepus_hoffmanni
ENSG00000108651	UTP6	100	69.682	ENSCPBG00000004652	UTP6	100	69.682	Chrysemys_picta_bellii
ENSG00000108651	UTP6	99	32.680	ENSCING00000022947	-	99	32.680	Ciona_intestinalis
ENSG00000108651	UTP6	79	95.652	ENSCANG00000031141	UTP6	90	73.954	Colobus_angolensis_palliatus
ENSG00000108651	UTP6	99	86.265	ENSCGRG00001000046	Utp6	100	86.265	Cricetulus_griseus_chok1gshd
ENSG00000108651	UTP6	95	86.219	ENSCGRG00000011543	Utp6	100	86.219	Cricetulus_griseus_crigri
ENSG00000108651	UTP6	100	53.923	ENSCSEG00000013422	utp6	100	63.934	Cynoglossus_semilaevis
ENSG00000108651	UTP6	100	55.444	ENSCVAG00000020322	utp6	100	55.444	Cyprinodon_variegatus
ENSG00000108651	UTP6	100	53.099	ENSDARG00000098433	utp6	100	63.536	Danio_rerio
ENSG00000108651	UTP6	100	90.803	ENSDNOG00000037018	UTP6	100	90.803	Dasypus_novemcinctus
ENSG00000108651	UTP6	91	84.587	ENSDORG00000003843	Utp6	100	84.587	Dipodomys_ordii
ENSG00000108651	UTP6	100	90.301	ENSEASG00005010870	UTP6	100	90.301	Equus_asinus_asinus
ENSG00000108651	UTP6	100	90.134	ENSECAG00000022217	UTP6	100	90.134	Equus_caballus
ENSG00000108651	UTP6	100	54.941	ENSELUG00000006618	utp6	100	54.941	Esox_lucius
ENSG00000108651	UTP6	100	87.312	ENSFCAG00000015795	UTP6	100	87.312	Felis_catus
ENSG00000108651	UTP6	100	65.327	ENSFALG00000002282	UTP6	100	65.327	Ficedula_albicollis
ENSG00000108651	UTP6	99	86.074	ENSFDAG00000019506	UTP6	100	86.074	Fukomys_damarensis
ENSG00000108651	UTP6	100	56.616	ENSFHEG00000010373	utp6	100	56.616	Fundulus_heteroclitus
ENSG00000108651	UTP6	100	54.941	ENSGMOG00000011958	utp6	100	54.941	Gadus_morhua
ENSG00000108651	UTP6	100	66.332	ENSGALG00000003260	UTP6	100	66.332	Gallus_gallus
ENSG00000108651	UTP6	100	56.449	ENSGAFG00000008505	utp6	100	56.449	Gambusia_affinis
ENSG00000108651	UTP6	100	55.946	ENSGACG00000019424	utp6	100	55.946	Gasterosteus_aculeatus
ENSG00000108651	UTP6	100	68.007	ENSGAGG00000004820	UTP6	100	68.007	Gopherus_agassizii
ENSG00000108651	UTP6	100	74.204	ENSGGOG00000026003	-	100	74.204	Gorilla_gorilla
ENSG00000108651	UTP6	100	99.497	ENSGGOG00000013569	UTP6	100	99.497	Gorilla_gorilla
ENSG00000108651	UTP6	100	57.119	ENSHBUG00000018668	utp6	100	57.119	Haplochromis_burtoni
ENSG00000108651	UTP6	99	79.258	ENSHGLG00000008642	-	99	79.258	Heterocephalus_glaber_female
ENSG00000108651	UTP6	99	85.570	ENSHGLG00000010332	UTP6	100	85.570	Heterocephalus_glaber_female
ENSG00000108651	UTP6	99	82.215	ENSHGLG00100014271	-	100	82.215	Heterocephalus_glaber_male
ENSG00000108651	UTP6	95	80.458	ENSHGLG00100006047	-	99	80.458	Heterocephalus_glaber_male
ENSG00000108651	UTP6	100	54.774	ENSHCOG00000017277	utp6	100	54.774	Hippocampus_comes
ENSG00000108651	UTP6	100	54.849	ENSIPUG00000022587	Utp6	100	54.849	Ictalurus_punctatus
ENSG00000108651	UTP6	99	86.935	ENSSTOG00000015875	UTP6	100	86.935	Ictidomys_tridecemlineatus
ENSG00000108651	UTP6	100	56.114	ENSKMAG00000021631	utp6	100	56.114	Kryptolebias_marmoratus
ENSG00000108651	UTP6	100	56.784	ENSLBEG00000002115	utp6	100	56.784	Labrus_bergylta
ENSG00000108651	UTP6	100	65.327	ENSLACG00000017158	UTP6	100	65.327	Latimeria_chalumnae
ENSG00000108651	UTP6	91	58.824	ENSLOCG00000013797	utp6	90	58.824	Lepisosteus_oculatus
ENSG00000108651	UTP6	100	88.462	ENSLAFG00000013008	UTP6	100	88.462	Loxodonta_africana
ENSG00000108651	UTP6	100	97.492	ENSMFAG00000038842	UTP6	100	97.492	Macaca_fascicularis
ENSG00000108651	UTP6	97	71.429	ENSMFAG00000041904	-	99	65.936	Macaca_fascicularis
ENSG00000108651	UTP6	100	97.492	ENSMMUG00000020403	UTP6	100	97.492	Macaca_mulatta
ENSG00000108651	UTP6	100	97.492	ENSMNEG00000039480	UTP6	100	97.492	Macaca_nemestrina
ENSG00000108651	UTP6	100	73.833	ENSMLEG00000039364	-	100	73.833	Mandrillus_leucophaeus
ENSG00000108651	UTP6	100	78.763	ENSMLEG00000032174	UTP6	100	78.763	Mandrillus_leucophaeus
ENSG00000108651	UTP6	100	55.779	ENSMAMG00000002228	utp6	99	55.779	Mastacembelus_armatus
ENSG00000108651	UTP6	100	57.119	ENSMZEG00005023895	utp6	100	57.119	Maylandia_zebra
ENSG00000108651	UTP6	95	66.901	ENSMGAG00000008111	UTP6	100	66.901	Meleagris_gallopavo
ENSG00000108651	UTP6	99	86.432	ENSMAUG00000021895	Utp6	100	86.432	Mesocricetus_auratus
ENSG00000108651	UTP6	100	84.114	ENSMICG00000002632	UTP6	100	84.114	Microcebus_murinus
ENSG00000108651	UTP6	99	85.762	ENSMOCG00000014163	Utp6	100	85.762	Microtus_ochrogaster
ENSG00000108651	UTP6	100	54.439	ENSMMOG00000008653	utp6	100	64.407	Mola_mola
ENSG00000108651	UTP6	100	67.726	ENSMODG00000019206	UTP6	100	67.726	Monodelphis_domestica
ENSG00000108651	UTP6	100	54.774	ENSMALG00000021112	utp6	100	54.774	Monopterus_albus
ENSG00000108651	UTP6	99	85.762	MGP_CAROLIEiJ_G0016828	Utp6	100	85.762	Mus_caroli
ENSG00000108651	UTP6	99	86.097	ENSMUSG00000035575	Utp6	100	86.097	Mus_musculus
ENSG00000108651	UTP6	99	72.027	MGP_PahariEiJ_G0017965	Utp6	100	72.027	Mus_pahari
ENSG00000108651	UTP6	99	85.595	MGP_SPRETEiJ_G0017672	Utp6	100	85.595	Mus_spretus
ENSG00000108651	UTP6	100	87.625	ENSMPUG00000014581	UTP6	100	87.625	Mustela_putorius_furo
ENSG00000108651	UTP6	100	86.455	ENSMLUG00000016422	UTP6	100	86.455	Myotis_lucifugus
ENSG00000108651	UTP6	99	85.762	ENSNGAG00000015482	Utp6	100	85.762	Nannospalax_galili
ENSG00000108651	UTP6	100	57.286	ENSNBRG00000019714	utp6	100	57.286	Neolamprologus_brichardi
ENSG00000108651	UTP6	100	97.152	ENSNLEG00000011009	UTP6	100	97.152	Nomascus_leucogenys
ENSG00000108651	UTP6	88	73.759	ENSOPRG00000008446	-	88	73.759	Ochotona_princeps
ENSG00000108651	UTP6	76	86.364	ENSODEG00000011971	UTP6	100	84.810	Octodon_degus
ENSG00000108651	UTP6	100	57.454	ENSONIG00000018090	utp6	100	57.454	Oreochromis_niloticus
ENSG00000108651	UTP6	98	66.327	ENSOANG00000004279	UTP6	99	66.327	Ornithorhynchus_anatinus
ENSG00000108651	UTP6	99	86.097	ENSOCUG00000016980	UTP6	99	86.097	Oryctolagus_cuniculus
ENSG00000108651	UTP6	99	56.544	ENSORLG00000003546	utp6	64	56.544	Oryzias_latipes
ENSG00000108651	UTP6	99	56.544	ENSORLG00020010377	utp6	99	56.544	Oryzias_latipes_hni
ENSG00000108651	UTP6	99	56.040	ENSORLG00015008893	utp6	99	56.040	Oryzias_latipes_hsok
ENSG00000108651	UTP6	100	56.951	ENSOMEG00000017487	utp6	100	56.951	Oryzias_melastigma
ENSG00000108651	UTP6	76	95.455	ENSOGAG00000004511	UTP6	100	78.967	Otolemur_garnettii
ENSG00000108651	UTP6	100	75.418	ENSOARG00000013474	UTP6	100	75.418	Ovis_aries
ENSG00000108651	UTP6	100	99.665	ENSPPAG00000038089	UTP6	100	99.665	Pan_paniscus
ENSG00000108651	UTP6	100	75.377	ENSPPAG00000016895	-	100	75.377	Pan_paniscus
ENSG00000108651	UTP6	100	90.468	ENSPPRG00000001010	UTP6	100	90.468	Panthera_pardus
ENSG00000108651	UTP6	100	90.301	ENSPTIG00000013913	UTP6	100	90.301	Panthera_tigris_altaica
ENSG00000108651	UTP6	100	75.042	ENSPTRG00000044798	-	100	75.042	Pan_troglodytes
ENSG00000108651	UTP6	100	99.665	ENSPTRG00000008977	UTP6	100	99.665	Pan_troglodytes
ENSG00000108651	UTP6	100	94.658	ENSPANG00000023113	UTP6	100	94.658	Papio_anubis
ENSG00000108651	UTP6	99	73.790	ENSPANG00000034274	-	100	73.790	Papio_anubis
ENSG00000108651	UTP6	100	55.927	ENSPKIG00000004653	utp6	100	55.927	Paramormyrops_kingsleyae
ENSG00000108651	UTP6	100	67.672	ENSPSIG00000012435	UTP6	100	67.672	Pelodiscus_sinensis
ENSG00000108651	UTP6	100	56.449	ENSPMGG00000009548	utp6	100	56.449	Periophthalmus_magnuspinnatus
ENSG00000108651	UTP6	99	86.265	ENSPEMG00000014081	Utp6	100	86.265	Peromyscus_maniculatus_bairdii
ENSG00000108651	UTP6	93	45.789	ENSPMAG00000009561	utp6	100	45.789	Petromyzon_marinus
ENSG00000108651	UTP6	100	69.682	ENSPCIG00000029968	UTP6	86	69.682	Phascolarctos_cinereus
ENSG00000108651	UTP6	100	56.114	ENSPFOG00000013918	utp6	100	56.114	Poecilia_formosa
ENSG00000108651	UTP6	100	56.449	ENSPLAG00000017825	utp6	100	56.449	Poecilia_latipinna
ENSG00000108651	UTP6	100	56.114	ENSPMEG00000008133	utp6	100	56.114	Poecilia_mexicana
ENSG00000108651	UTP6	100	54.941	ENSPREG00000013108	utp6	99	54.941	Poecilia_reticulata
ENSG00000108651	UTP6	100	93.635	ENSPPYG00000008154	UTP6	100	93.635	Pongo_abelii
ENSG00000108651	UTP6	67	87.500	ENSPCAG00000014878	-	69	62.834	Procavia_capensis
ENSG00000108651	UTP6	100	83.946	ENSPCOG00000010224	UTP6	100	83.946	Propithecus_coquereli
ENSG00000108651	UTP6	100	84.281	ENSPVAG00000015759	UTP6	100	84.281	Pteropus_vampyrus
ENSG00000108651	UTP6	100	56.784	ENSPNYG00000002290	utp6	100	56.784	Pundamilia_nyererei
ENSG00000108651	UTP6	100	53.936	ENSPNAG00000027370	utp6	100	53.936	Pygocentrus_nattereri
ENSG00000108651	UTP6	99	82.915	ENSRNOG00000014209	Utp6	100	82.915	Rattus_norvegicus
ENSG00000108651	UTP6	100	96.823	ENSRBIG00000020822	UTP6	100	96.823	Rhinopithecus_bieti
ENSG00000108651	UTP6	100	96.823	ENSRROG00000036838	UTP6	100	96.823	Rhinopithecus_roxellana
ENSG00000108651	UTP6	100	56.667	ENSSFOG00015005978	utp6	100	56.667	Scleropages_formosus
ENSG00000108651	UTP6	100	56.449	ENSSMAG00000014772	utp6	100	56.449	Scophthalmus_maximus
ENSG00000108651	UTP6	100	55.946	ENSSDUG00000000329	utp6	100	55.946	Seriola_dumerili
ENSG00000108651	UTP6	100	55.946	ENSSLDG00000016724	utp6	100	55.946	Seriola_lalandi_dorsalis
ENSG00000108651	UTP6	99	76.174	ENSSARG00000010778	UTP6	99	76.174	Sorex_araneus
ENSG00000108651	UTP6	100	67.504	ENSSPUG00000005273	UTP6	100	67.504	Sphenodon_punctatus
ENSG00000108651	UTP6	100	54.104	ENSSPAG00000011871	utp6	99	54.104	Stegastes_partitus
ENSG00000108651	UTP6	100	88.462	ENSSSCG00000017745	UTP6	100	88.462	Sus_scrofa
ENSG00000108651	UTP6	100	66.164	ENSTGUG00000004999	UTP6	100	66.164	Taeniopygia_guttata
ENSG00000108651	UTP6	99	55.537	ENSTRUG00000012005	utp6	100	55.537	Takifugu_rubripes
ENSG00000108651	UTP6	99	56.208	ENSTNIG00000003235	utp6	100	56.208	Tetraodon_nigroviridis
ENSG00000108651	UTP6	67	80.110	ENSTBEG00000005388	-	67	80.110	Tupaia_belangeri
ENSG00000108651	UTP6	100	88.294	ENSTTRG00000009911	UTP6	100	88.294	Tursiops_truncatus
ENSG00000108651	UTP6	99	88.758	ENSUMAG00000015139	UTP6	99	88.758	Ursus_maritimus
ENSG00000108651	UTP6	100	86.789	ENSVPAG00000005782	UTP6	100	86.789	Vicugna_pacos
ENSG00000108651	UTP6	100	89.632	ENSVVUG00000012238	UTP6	100	89.632	Vulpes_vulpes
ENSG00000108651	UTP6	100	49.246	ENSXETG00000020057	utp6	100	49.246	Xenopus_tropicalis
ENSG00000108651	UTP6	100	55.760	ENSXCOG00000013626	utp6	100	66.667	Xiphophorus_couchianus
ENSG00000108651	UTP6	100	55.779	ENSXMAG00000017414	utp6	100	55.779	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	21873635.	IBA	Process
GO:0005654	nucleoplasm	-	TAS	Component
GO:0005730	nucleolus	-	IDA	Component
GO:0006364	rRNA processing	-	TAS	Process
GO:0030515	snoRNA binding	-	IEA	Function
GO:0032040	small-subunit processome	21873635.	IBA	Component
GO:0034388	Pwp2p-containing subcomplex of 90S preribosome	21873635.	IBA	Component