EuRBPDB

Description

RBDs

Literatures

Expression

Transcripts

Gene Model

Pathways

GWAS

PPI

Paralogs

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000108771 (Gene tree)
Gene ID: 79132
Gene Symbol: DHX58
Alias: LGP2|D11LGP2
Full Name: DExH-box helicase 58
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Minus strand
Length: 11,330 bases
Position: chr17:42,101,404-42,112,733
Accession: 29517
RBP type: canonical RBP
Summary: (DExH-Box Helicase 58) is a Protein Coding gene. Diseases associated with DHX58 include Measles and Noonan Syndrome 1. Among its related pathways are RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways and NF-kappaB Signaling. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and helicase activity. An important paralog of this gene is IFIH1.

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000416389	ResIII	PF04851.15	3.5e-18	1	1
ENSP00000251642	ResIII	PF04851.15	8.8e-18	1	1
ENSP00000404639	ResIII	PF04851.15	1.3e-17	1	1
ENSP00000251642	RIG-I_C-RD	PF11648.8	2.4e-35	1	1
ENSP00000416389	DEAD	PF00270.29	1.3e-15	1	1
ENSP00000251642	DEAD	PF00270.29	5.9e-15	1	1
ENSP00000404639	DEAD	PF00270.29	6.9e-15	1	1

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
27825296	Resurrecting ancestral structural dynamics of an antiviral immune receptor: adaptive binding pocket reorganization repeatedly shifts RNA preference.	BMC Evol Biol	2016 Nov 8	Pugh C	-
19380577	Solution structures of cytosolic RNA sensor MDA5 and LGP2 C-terminal domains: identification of the RNA recognition loop in RIG-I-like receptors.	J Biol Chem	2009 Jun 26	Takahasi K	doi: 10.1074/jbc.M109.007179
30347765	Virus Sensor RIG-I Represses RNA Interference by Interacting with TRBP through LGP2 in Mammalian Cells.	Genes (Basel)	2018 Oct 19	Takahashi T	doi: 10.3390/genes9100511.
29321042	Type I IFN signature in childhood-onset systemic lupus erythematosus: a conspiracy of DNA- and RNA-sensing receptors?	Arthritis Res Ther	2018 Jan 10	Wahadat MJ	doi: 10.1186/s13075-017-1501-z.
19531363	Structural basis of double-stranded RNA recognition by the RIG-I like receptor MDA5.	Arch Biochem Biophys	2009 Aug 1	Li X	doi: 10.1016/j.abb.2009.06.008
19211564	Regulation of signal transduction by enzymatically inactive antiviral RNA helicase proteins MDA5, RIG-I, and LGP2.	J Biol Chem	2009 Apr 10	Bamming D	doi: 10.1074/jbc.M807365200
25340845	A novel function of human Pumilio proteins in cytoplasmic sensing of viral infection.	PLoS Pathog	2014 Oct 23	Narita R	doi: 10.1371/journal.ppat.1004417
24109602	Ancient origins of vertebrate-specific innate antiviral immunity.	Mol Biol Evol	2014 Jan	Mukherjee K	doi: 10.1093/molbev/mst184
29939295	LGP2 virus sensor regulates gene expression network mediated by TRBP-bound microRNAs.	Nucleic Acids Res	2018 Sep 28	Takahashi T	doi: 10.1093/nar/gky575.
27203181	Structural Analysis of dsRNA Binding to Anti-viral Pattern Recognition Receptors LGP2 and MDA5.	Mol Cell	2016 May 19	Uchikawa E	doi: 10.1016/j.molcel.2016.04.021.
29661858	RNA sensor LGP2 inhibits TRAF ubiquitin ligase to negatively regulate innate immune signaling.	EMBO Rep	2018 Jun	Parisien JP	doi: 10.15252/embr.201745176
29678949	Hu Antigen R Regulates Antiviral Innate Immune Responses through the Stabilization of mRNA for Polo-like Kinase 2.	J Immunol	2018 Jun 1	Sueyoshi T	doi: 10.4049/jimmunol.1701282
31237466	RNA Helicase LGP2 Negatively Regulates RIG-I Signaling by Preventing TRIM25-Mediated Caspase Activation and Recruitment Domain Ubiquitination.	J Interferon Cytokine Res	2019 Jun 25	Quicke KM	doi: 10.1089/jir.2019.0059
19208642	The regulatory domain of the RIG-I family ATPase LGP2 senses double-stranded RNA.	Nucleic Acids Res	2009 Apr	Pippig DA	doi: 10.1093/nar/gkp059
21865300	The selective footprints of viral pressures at the human RIG-I-like receptor family.	Hum Mol Genet	2011 Nov 15	Vasseur E	doi: 10.1093/hmg/ddr377
27034163	Cancer therapies activate RIG-I-like receptor pathway through endogenous non-coding RNAs.	Oncotarget	2016 May 3	Ranoa DR	doi: 10.18632/oncotarget.8420.
28768856	Nonencapsidated 5' Copy-Back Defective Interfering Genomes Produced by Recombinant Measles Viruses Are Recognized by RIG-I and LGP2 but Not MDA5.	J Virol	2017 Sep 27	Mura M	doi: 10.1128/JVI.00643-17
29769346	Porcine Deltacoronavirus Accessory Protein NS6 Antagonizes Interferon Beta Production by Interfering with the Binding of RIG-I/MDA5 to Double-Stranded RNA.	J Virol	2018 Jul 17	Fang P	doi: 10.1128/JVI.00712-18

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000592024	DHX58-208	941	-	-	- (aa)	-	-
ENST00000591220	DHX58-207	540	-	ENSP00000466721	99 (aa)	-	K7EMZ5
ENST00000430773	DHX58-203	730	-	ENSP00000404639	156 (aa)	-	C9JE76
ENST00000413196	DHX58-202	1283	-	ENSP00000416389	302 (aa)	-	C9JG98
ENST00000589979	DHX58-205	782	-	ENSP00000467470	51 (aa)	-	K7EPP0
ENST00000586522	DHX58-204	2331	-	-	- (aa)	-	-
ENST00000251642	DHX58-201	2617	XM_017025059	ENSP00000251642	678 (aa)	XP_016880548	Q96C10
ENST00000590637	DHX58-206	748	-	-	- (aa)	-	-

Gene Model

Click here to download ENSG00000108771's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa04622	RIG-I-like receptor signaling pathway	KEGG

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000108771	rs34891485	17	42111440	T	Coronary artery disease	29212778	[0.047-0.101] unit decrease	0.074	EFO_0000378
ENSG00000108771	rs2074158	17	42105145	T	Coronary artery disease	29212778	[0.037-0.071] unit decrease	0.0543	EFO_0000378

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000108771's network

* RBP PPI network refers to all genes directly bind to RBP

Paralogs

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy
ENSG00000108771	DHX58	95	37.755	ENSG00000107201	DDX58	94	32.184
ENSG00000108771	DHX58	100	49.080	ENSG00000115267	IFIH1	70	40.865

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000108771	DHX58	97	48.101	ENSAPOG00000024529	ifih1	70	39.451	Acanthochromis_polyacanthus
ENSG00000108771	DHX58	99	55.128	ENSAPOG00000017013	dhx58	99	48.023	Acanthochromis_polyacanthus
ENSG00000108771	DHX58	99	34.139	ENSAMEG00000003766	DDX58	73	32.143	Ailuropoda_melanoleuca
ENSG00000108771	DHX58	100	88.462	ENSAMEG00000005941	DHX58	100	81.938	Ailuropoda_melanoleuca
ENSG00000108771	DHX58	100	45.283	ENSAMEG00000005698	IFIH1	69	40.725	Ailuropoda_melanoleuca
ENSG00000108771	DHX58	88	44.444	ENSACIG00000010684	dhx58	90	42.529	Amphilophus_citrinellus
ENSG00000108771	DHX58	97	49.367	ENSACIG00000021179	ifih1	71	40.199	Amphilophus_citrinellus
ENSG00000108771	DHX58	99	53.205	ENSACIG00000010643	dhx58	99	47.445	Amphilophus_citrinellus
ENSG00000108771	DHX58	99	53.205	ENSAOCG00000016713	dhx58	99	47.145	Amphiprion_ocellaris
ENSG00000108771	DHX58	98	47.500	ENSAOCG00000014773	ifih1	71	39.712	Amphiprion_ocellaris
ENSG00000108771	DHX58	98	47.500	ENSAPEG00000018872	ifih1	71	39.712	Amphiprion_percula
ENSG00000108771	DHX58	99	53.205	ENSAPEG00000004817	dhx58	99	47.145	Amphiprion_percula
ENSG00000108771	DHX58	98	54.545	ENSATEG00000001847	dhx58	99	48.401	Anabas_testudineus
ENSG00000108771	DHX58	97	49.367	ENSATEG00000018364	ifih1	70	40.714	Anabas_testudineus
ENSG00000108771	DHX58	98	48.447	ENSAPLG00000010913	IFIH1	69	40.625	Anas_platyrhynchos
ENSG00000108771	DHX58	99	32.399	ENSAPLG00000015091	DDX58	79	30.970	Anas_platyrhynchos
ENSG00000108771	DHX58	99	54.545	ENSAPLG00000013187	DHX58	100	47.214	Anas_platyrhynchos
ENSG00000108771	DHX58	98	51.250	ENSACAG00000014017	IFIH1	69	40.603	Anolis_carolinensis
ENSG00000108771	DHX58	99	61.290	ENSACAG00000012501	DHX58	99	54.911	Anolis_carolinensis
ENSG00000108771	DHX58	99	50.000	ENSANAG00000028163	IFIH1	70	41.562	Aotus_nancymaae
ENSG00000108771	DHX58	95	38.776	ENSANAG00000031893	DDX58	76	30.999	Aotus_nancymaae
ENSG00000108771	DHX58	100	94.949	ENSANAG00000029056	DHX58	100	91.003	Aotus_nancymaae
ENSG00000108771	DHX58	98	52.597	ENSACLG00000002574	dhx58	99	46.176	Astatotilapia_calliptera
ENSG00000108771	DHX58	98	47.500	ENSACLG00000012934	ifih1	70	39.062	Astatotilapia_calliptera
ENSG00000108771	DHX58	98	53.896	ENSACLG00000002582	dhx58	99	47.198	Astatotilapia_calliptera
ENSG00000108771	DHX58	99	55.128	ENSAMXG00000030658	dhx58	98	50.220	Astyanax_mexicanus
ENSG00000108771	DHX58	97	48.734	ENSAMXG00000010023	ifih1	67	41.534	Astyanax_mexicanus
ENSG00000108771	DHX58	99	34.259	ENSAMXG00000015795	-	72	32.230	Astyanax_mexicanus
ENSG00000108771	DHX58	100	89.103	ENSBTAG00000046580	DHX58	100	83.407	Bos_taurus
ENSG00000108771	DHX58	99	32.622	ENSBTAG00000003366	DDX58	67	30.758	Bos_taurus
ENSG00000108771	DHX58	96	50.323	ENSBTAG00000008142	IFIH1	70	40.954	Bos_taurus
ENSG00000108771	DHX58	99	34.049	ENSCJAG00000007741	DDX58	73	31.609	Callithrix_jacchus
ENSG00000108771	DHX58	100	94.949	ENSCJAG00000014852	DHX58	100	90.708	Callithrix_jacchus
ENSG00000108771	DHX58	100	48.466	ENSCJAG00000005956	IFIH1	70	41.283	Callithrix_jacchus
ENSG00000108771	DHX58	96	48.077	ENSCAFG00000010438	IFIH1	70	40.690	Canis_familiaris
ENSG00000108771	DHX58	100	87.821	ENSCAFG00000015720	DHX58	99	84.661	Canis_familiaris
ENSG00000108771	DHX58	99	33.837	ENSCAFG00000001807	DDX58	74	31.586	Canis_familiaris
ENSG00000108771	DHX58	100	34.043	ENSCAFG00020014567	DDX58	80	31.624	Canis_lupus_dingo
ENSG00000108771	DHX58	96	48.077	ENSCAFG00020004329	IFIH1	73	40.690	Canis_lupus_dingo
ENSG00000108771	DHX58	100	87.821	ENSCAFG00020013642	DHX58	100	85.965	Canis_lupus_dingo
ENSG00000108771	DHX58	96	51.282	ENSCHIG00000019848	IFIH1	70	40.979	Capra_hircus
ENSG00000108771	DHX58	100	89.103	ENSCHIG00000017011	DHX58	100	80.058	Capra_hircus
ENSG00000108771	DHX58	99	32.012	ENSCHIG00000025883	DDX58	72	30.372	Capra_hircus
ENSG00000108771	DHX58	99	47.531	ENSTSYG00000005900	IFIH1	70	40.586	Carlito_syrichta
ENSG00000108771	DHX58	95	37.755	ENSTSYG00000004200	DDX58	73	31.178	Carlito_syrichta
ENSG00000108771	DHX58	90	82.609	ENSTSYG00000032842	-	99	85.366	Carlito_syrichta
ENSG00000108771	DHX58	99	89.032	ENSCAPG00000016521	DHX58	100	81.336	Cavia_aperea
ENSG00000108771	DHX58	99	50.617	ENSCAPG00000009502	IFIH1	89	40.028	Cavia_aperea
ENSG00000108771	DHX58	99	34.783	ENSCPOG00000001598	DDX58	73	30.627	Cavia_porcellus
ENSG00000108771	DHX58	99	89.032	ENSCPOG00000023721	DHX58	100	81.416	Cavia_porcellus
ENSG00000108771	DHX58	99	50.617	ENSCPOG00000007154	IFIH1	70	41.036	Cavia_porcellus
ENSG00000108771	DHX58	100	33.131	ENSCCAG00000036752	DDX58	77	31.760	Cebus_capucinus
ENSG00000108771	DHX58	100	93.939	ENSCCAG00000022542	DHX58	100	90.265	Cebus_capucinus
ENSG00000108771	DHX58	99	48.765	ENSCCAG00000027248	IFIH1	70	41.423	Cebus_capucinus
ENSG00000108771	DHX58	100	98.077	ENSCATG00000043180	DHX58	100	96.165	Cercocebus_atys
ENSG00000108771	DHX58	95	37.755	ENSCATG00000040246	DDX58	73	32.328	Cercocebus_atys
ENSG00000108771	DHX58	99	49.383	ENSCATG00000032062	IFIH1	70	41.004	Cercocebus_atys
ENSG00000108771	DHX58	99	47.531	ENSCLAG00000008509	IFIH1	70	39.609	Chinchilla_lanigera
ENSG00000108771	DHX58	100	85.897	ENSCLAG00000013960	DHX58	100	81.416	Chinchilla_lanigera
ENSG00000108771	DHX58	99	36.025	ENSCLAG00000002351	DDX58	77	32.092	Chinchilla_lanigera
ENSG00000108771	DHX58	99	49.383	ENSCSAG00000015614	IFIH1	70	41.004	Chlorocebus_sabaeus
ENSG00000108771	DHX58	95	38.776	ENSCSAG00000009834	DDX58	73	32.662	Chlorocebus_sabaeus
ENSG00000108771	DHX58	100	96.154	ENSCSAG00000003082	DHX58	100	94.985	Chlorocebus_sabaeus
ENSG00000108771	DHX58	99	51.235	ENSCHOG00000013845	IFIH1	68	35.474	Choloepus_hoffmanni
ENSG00000108771	DHX58	90	84.783	ENSCHOG00000010562	-	100	78.218	Choloepus_hoffmanni
ENSG00000108771	DHX58	99	64.935	ENSCPBG00000006804	DHX58	99	54.963	Chrysemys_picta_bellii
ENSG00000108771	DHX58	99	34.049	ENSCPBG00000008101	DDX58	73	31.948	Chrysemys_picta_bellii
ENSG00000108771	DHX58	98	49.689	ENSCPBG00000026441	IFIH1	70	40.426	Chrysemys_picta_bellii
ENSG00000108771	DHX58	100	96.154	ENSCANG00000031041	DHX58	100	95.280	Colobus_angolensis_palliatus
ENSG00000108771	DHX58	99	34.049	ENSCANG00000031971	DDX58	73	32.328	Colobus_angolensis_palliatus
ENSG00000108771	DHX58	99	49.383	ENSCANG00000031775	IFIH1	70	41.004	Colobus_angolensis_palliatus
ENSG00000108771	DHX58	95	39.796	ENSCGRG00001024123	Ddx58	73	31.609	Cricetulus_griseus_chok1gshd
ENSG00000108771	DHX58	100	86.538	ENSCGRG00001010336	Dhx58	100	78.940	Cricetulus_griseus_chok1gshd
ENSG00000108771	DHX58	100	43.711	ENSCGRG00001024740	Ifih1	73	40.503	Cricetulus_griseus_chok1gshd
ENSG00000108771	DHX58	100	43.711	ENSCGRG00000010637	Ifih1	73	40.503	Cricetulus_griseus_crigri
ENSG00000108771	DHX58	100	86.538	ENSCGRG00000008364	Dhx58	100	78.940	Cricetulus_griseus_crigri
ENSG00000108771	DHX58	98	47.500	ENSCSEG00000010056	ifih1	76	38.506	Cynoglossus_semilaevis
ENSG00000108771	DHX58	98	52.941	ENSCSEG00000021382	dhx58	99	45.827	Cynoglossus_semilaevis
ENSG00000108771	DHX58	99	51.282	ENSCVAG00000009503	dhx58	99	46.912	Cyprinodon_variegatus
ENSG00000108771	DHX58	98	46.250	ENSCVAG00000002089	ifih1	73	38.968	Cyprinodon_variegatus
ENSG00000108771	DHX58	100	44.969	ENSDARG00000018553	ifih1	99	40.453	Danio_rerio
ENSG00000108771	DHX58	100	54.140	ENSDARG00000089463	dhx58	99	50.755	Danio_rerio
ENSG00000108771	DHX58	99	31.212	ENSDNOG00000003968	DDX58	73	30.516	Dasypus_novemcinctus
ENSG00000108771	DHX58	99	51.852	ENSDNOG00000012100	IFIH1	70	41.061	Dasypus_novemcinctus
ENSG00000108771	DHX58	100	84.848	ENSDNOG00000043127	DHX58	100	77.729	Dasypus_novemcinctus
ENSG00000108771	DHX58	99	48.765	ENSDORG00000001907	Ifih1	74	40.756	Dipodomys_ordii
ENSG00000108771	DHX58	100	88.462	ENSDORG00000006815	Dhx58	99	82.570	Dipodomys_ordii
ENSG00000108771	DHX58	77	63.333	ENSETEG00000011268	IFIH1	55	63.333	Echinops_telfairi
ENSG00000108771	DHX58	100	89.103	ENSETEG00000019618	-	62	81.873	Echinops_telfairi
ENSG00000108771	DHX58	99	44.156	ENSEBUG00000007527	dhx58	99	41.838	Eptatretus_burgeri
ENSG00000108771	DHX58	95	45.333	ENSEBUG00000012092	IFIH1	94	38.512	Eptatretus_burgeri
ENSG00000108771	DHX58	97	38.217	ENSEBUG00000014150	DDX58	96	31.354	Eptatretus_burgeri
ENSG00000108771	DHX58	100	34.441	ENSEASG00005004589	DDX58	67	31.812	Equus_asinus_asinus
ENSG00000108771	DHX58	100	91.026	ENSEASG00005009112	DHX58	100	84.366	Equus_asinus_asinus
ENSG00000108771	DHX58	99	50.000	ENSEASG00005022976	IFIH1	67	42.743	Equus_asinus_asinus
ENSG00000108771	DHX58	99	50.000	ENSECAG00000007881	IFIH1	69	42.020	Equus_caballus
ENSG00000108771	DHX58	100	34.731	ENSECAG00000021989	DDX58	77	31.818	Equus_caballus
ENSG00000108771	DHX58	100	90.385	ENSECAG00000011439	DHX58	100	84.218	Equus_caballus
ENSG00000108771	DHX58	91	31.438	ENSEEUG00000015254	DDX58	55	31.670	Erinaceus_europaeus
ENSG00000108771	DHX58	99	49.383	ENSEEUG00000005153	IFIH1	70	41.061	Erinaceus_europaeus
ENSG00000108771	DHX58	90	73.913	ENSEEUG00000002712	DHX58	63	77.545	Erinaceus_europaeus
ENSG00000108771	DHX58	98	52.597	ENSELUG00000018439	dhx58	99	46.266	Esox_lucius
ENSG00000108771	DHX58	97	47.468	ENSELUG00000019690	ifih1	75	39.943	Esox_lucius
ENSG00000108771	DHX58	99	89.677	ENSFCAG00000002145	DHX58	99	84.490	Felis_catus
ENSG00000108771	DHX58	100	45.597	ENSFCAG00000023951	IFIH1	70	40.725	Felis_catus
ENSG00000108771	DHX58	99	33.837	ENSFCAG00000001294	DDX58	73	31.624	Felis_catus
ENSG00000108771	DHX58	99	50.617	ENSFALG00000000721	IFIH1	69	41.453	Ficedula_albicollis
ENSG00000108771	DHX58	97	33.548	ENSFALG00000001146	DDX58	83	30.202	Ficedula_albicollis
ENSG00000108771	DHX58	95	56.383	ENSFALG00000000653	DHX58	99	51.420	Ficedula_albicollis
ENSG00000108771	DHX58	100	85.897	ENSFDAG00000018042	DHX58	98	81.232	Fukomys_damarensis
ENSG00000108771	DHX58	74	30.263	ENSFDAG00000011958	-	99	30.263	Fukomys_damarensis
ENSG00000108771	DHX58	99	47.531	ENSFDAG00000013122	IFIH1	70	40.000	Fukomys_damarensis
ENSG00000108771	DHX58	98	53.896	ENSFHEG00000012195	dhx58	99	47.794	Fundulus_heteroclitus
ENSG00000108771	DHX58	97	47.468	ENSFHEG00000022714	ifih1	71	40.341	Fundulus_heteroclitus
ENSG00000108771	DHX58	98	47.500	ENSGMOG00000014790	ifih1	70	39.062	Gadus_morhua
ENSG00000108771	DHX58	97	54.605	ENSGMOG00000015145	dhx58	99	45.685	Gadus_morhua
ENSG00000108771	DHX58	100	58.609	ENSGALG00000023821	DHX58	99	52.985	Gallus_gallus
ENSG00000108771	DHX58	99	48.447	ENSGALG00000041192	IFIH1	64	41.218	Gallus_gallus
ENSG00000108771	DHX58	99	53.846	ENSGAFG00000000986	dhx58	97	47.590	Gambusia_affinis
ENSG00000108771	DHX58	98	46.541	ENSGAFG00000007593	ifih1	72	39.511	Gambusia_affinis
ENSG00000108771	DHX58	100	54.777	ENSGACG00000008740	dhx58	99	47.430	Gasterosteus_aculeatus
ENSG00000108771	DHX58	97	50.633	ENSGACG00000005518	ifih1	68	39.538	Gasterosteus_aculeatus
ENSG00000108771	DHX58	99	33.333	ENSGAGG00000018278	DDX58	73	30.491	Gopherus_agassizii
ENSG00000108771	DHX58	98	49.689	ENSGAGG00000007126	IFIH1	68	40.974	Gopherus_agassizii
ENSG00000108771	DHX58	99	64.516	ENSGAGG00000023270	DHX58	99	54.978	Gopherus_agassizii
ENSG00000108771	DHX58	100	98.378	ENSGGOG00000005458	DHX58	100	98.378	Gorilla_gorilla
ENSG00000108771	DHX58	95	37.755	ENSGGOG00000016335	DDX58	73	32.184	Gorilla_gorilla
ENSG00000108771	DHX58	99	49.383	ENSGGOG00000015893	IFIH1	70	41.004	Gorilla_gorilla
ENSG00000108771	DHX58	98	51.299	ENSHBUG00000001953	dhx58	99	45.974	Haplochromis_burtoni
ENSG00000108771	DHX58	98	54.545	ENSHBUG00000001963	dhx58	99	47.493	Haplochromis_burtoni
ENSG00000108771	DHX58	98	47.500	ENSHBUG00000004855	ifih1	71	39.062	Haplochromis_burtoni
ENSG00000108771	DHX58	100	85.897	ENSHGLG00000011529	DHX58	87	82.743	Heterocephalus_glaber_female
ENSG00000108771	DHX58	97	36.129	ENSHGLG00000016504	DDX58	73	31.655	Heterocephalus_glaber_female
ENSG00000108771	DHX58	99	49.383	ENSHGLG00000008772	IFIH1	70	39.833	Heterocephalus_glaber_female
ENSG00000108771	DHX58	100	85.897	ENSHGLG00100009705	DHX58	100	81.268	Heterocephalus_glaber_male
ENSG00000108771	DHX58	97	36.129	ENSHGLG00100000205	DDX58	73	31.655	Heterocephalus_glaber_male
ENSG00000108771	DHX58	99	49.383	ENSHGLG00100002141	IFIH1	70	39.833	Heterocephalus_glaber_male
ENSG00000108771	DHX58	97	46.835	ENSHCOG00000016423	ifih1	75	39.174	Hippocampus_comes
ENSG00000108771	DHX58	98	57.792	ENSHCOG00000004788	dhx58	99	46.765	Hippocampus_comes
ENSG00000108771	DHX58	99	33.951	ENSIPUG00000003114	ddx58	76	31.519	Ictalurus_punctatus
ENSG00000108771	DHX58	97	48.734	ENSIPUG00000013367	ifih1	69	40.831	Ictalurus_punctatus
ENSG00000108771	DHX58	100	55.414	ENSIPUG00000019893	dhx58	99	48.766	Ictalurus_punctatus
ENSG00000108771	DHX58	99	48.148	ENSSTOG00000004953	IFIH1	73	40.808	Ictidomys_tridecemlineatus
ENSG00000108771	DHX58	100	89.103	ENSSTOG00000006524	DHX58	100	84.071	Ictidomys_tridecemlineatus
ENSG00000108771	DHX58	95	36.735	ENSSTOG00000006994	DDX58	73	30.647	Ictidomys_tridecemlineatus
ENSG00000108771	DHX58	95	37.755	ENSJJAG00000004582	Ddx58	66	33.468	Jaculus_jaculus
ENSG00000108771	DHX58	99	87.662	ENSJJAG00000000855	Dhx58	100	79.499	Jaculus_jaculus
ENSG00000108771	DHX58	99	48.765	ENSJJAG00000018669	Ifih1	73	40.111	Jaculus_jaculus
ENSG00000108771	DHX58	99	51.923	ENSKMAG00000020096	dhx58	99	46.784	Kryptolebias_marmoratus
ENSG00000108771	DHX58	98	48.125	ENSKMAG00000014309	ifih1	72	38.701	Kryptolebias_marmoratus
ENSG00000108771	DHX58	99	53.205	ENSLBEG00000004224	dhx58	99	48.018	Labrus_bergylta
ENSG00000108771	DHX58	97	48.101	ENSLBEG00000005389	ifih1	70	38.440	Labrus_bergylta
ENSG00000108771	DHX58	100	31.804	ENSLACG00000000411	DDX58	73	30.603	Latimeria_chalumnae
ENSG00000108771	DHX58	99	47.785	ENSLACG00000011448	IFIH1	95	43.777	Latimeria_chalumnae
ENSG00000108771	DHX58	100	56.051	ENSLACG00000011208	DHX58	99	47.710	Latimeria_chalumnae
ENSG00000108771	DHX58	99	33.742	ENSLOCG00000013422	DDX58	74	31.453	Lepisosteus_oculatus
ENSG00000108771	DHX58	99	34.049	ENSLOCG00000006504	-	71	31.079	Lepisosteus_oculatus
ENSG00000108771	DHX58	98	47.500	ENSLOCG00000008460	ifih1	69	40.736	Lepisosteus_oculatus
ENSG00000108771	DHX58	100	57.325	ENSLOCG00000012582	dhx58	99	51.775	Lepisosteus_oculatus
ENSG00000108771	DHX58	100	87.179	ENSLAFG00000027301	DHX58	100	81.552	Loxodonta_africana
ENSG00000108771	DHX58	95	35.789	ENSLAFG00000005416	DDX58	73	30.659	Loxodonta_africana
ENSG00000108771	DHX58	99	50.000	ENSLAFG00000009997	IFIH1	69	42.878	Loxodonta_africana
ENSG00000108771	DHX58	100	34.347	ENSMFAG00000045674	DDX58	94	32.475	Macaca_fascicularis
ENSG00000108771	DHX58	100	97.436	ENSMFAG00000034530	DHX58	100	95.723	Macaca_fascicularis
ENSG00000108771	DHX58	99	49.383	ENSMFAG00000003848	IFIH1	70	41.004	Macaca_fascicularis
ENSG00000108771	DHX58	100	98.077	ENSMMUG00000014755	DHX58	100	95.870	Macaca_mulatta
ENSG00000108771	DHX58	99	49.383	ENSMMUG00000003202	IFIH1	70	41.004	Macaca_mulatta
ENSG00000108771	DHX58	95	38.776	ENSMMUG00000012442	DDX58	73	32.475	Macaca_mulatta
ENSG00000108771	DHX58	99	49.383	ENSMNEG00000032734	IFIH1	70	41.004	Macaca_nemestrina
ENSG00000108771	DHX58	100	97.436	ENSMNEG00000043994	DHX58	100	95.870	Macaca_nemestrina
ENSG00000108771	DHX58	95	38.776	ENSMNEG00000041909	DDX58	73	32.332	Macaca_nemestrina
ENSG00000108771	DHX58	100	98.077	ENSMLEG00000042616	DHX58	100	96.165	Mandrillus_leucophaeus
ENSG00000108771	DHX58	99	49.383	ENSMLEG00000000107	IFIH1	70	41.004	Mandrillus_leucophaeus
ENSG00000108771	DHX58	95	38.776	ENSMLEG00000029982	DDX58	73	32.189	Mandrillus_leucophaeus
ENSG00000108771	DHX58	99	53.205	ENSMAMG00000022316	dhx58	99	47.299	Mastacembelus_armatus
ENSG00000108771	DHX58	100	45.912	ENSMAMG00000003380	ifih1	71	39.943	Mastacembelus_armatus
ENSG00000108771	DHX58	98	47.500	ENSMZEG00005007158	ifih1	71	39.062	Maylandia_zebra
ENSG00000108771	DHX58	98	53.896	ENSMZEG00005022739	dhx58	99	47.493	Maylandia_zebra
ENSG00000108771	DHX58	98	52.597	ENSMZEG00005022742	dhx58	99	46.029	Maylandia_zebra
ENSG00000108771	DHX58	93	59.783	ENSMGAG00000006752	DHX58	99	51.591	Meleagris_gallopavo
ENSG00000108771	DHX58	98	49.057	ENSMGAG00000010882	IFIH1	70	40.767	Meleagris_gallopavo
ENSG00000108771	DHX58	100	87.179	ENSMAUG00000019934	Dhx58	100	81.121	Mesocricetus_auratus
ENSG00000108771	DHX58	95	39.796	ENSMAUG00000021814	Ddx58	74	31.948	Mesocricetus_auratus
ENSG00000108771	DHX58	100	91.026	ENSMICG00000011933	DHX58	100	86.431	Microcebus_murinus
ENSG00000108771	DHX58	96	49.359	ENSMICG00000005405	IFIH1	66	41.630	Microcebus_murinus
ENSG00000108771	DHX58	99	34.969	ENSMICG00000006555	DDX58	94	32.615	Microcebus_murinus
ENSG00000108771	DHX58	95	37.755	ENSMOCG00000006173	Ddx58	81	30.186	Microtus_ochrogaster
ENSG00000108771	DHX58	100	83.974	ENSMOCG00000019066	Dhx58	100	80.531	Microtus_ochrogaster
ENSG00000108771	DHX58	99	46.914	ENSMOCG00000011565	Ifih1	73	40.928	Microtus_ochrogaster
ENSG00000108771	DHX58	97	48.734	ENSMMOG00000003652	ifih1	73	39.511	Mola_mola
ENSG00000108771	DHX58	98	54.545	ENSMMOG00000020631	dhx58	99	47.291	Mola_mola
ENSG00000108771	DHX58	99	76.774	ENSMODG00000014782	DHX58	98	67.211	Monodelphis_domestica
ENSG00000108771	DHX58	98	48.750	ENSMODG00000005628	IFIH1	70	41.193	Monodelphis_domestica
ENSG00000108771	DHX58	98	55.844	ENSMALG00000006556	dhx58	99	47.291	Monopterus_albus
ENSG00000108771	DHX58	100	43.849	ENSMALG00000015489	ifih1	72	38.561	Monopterus_albus
ENSG00000108771	DHX58	99	46.296	MGP_CAROLIEiJ_G0023594	Ifih1	73	40.865	Mus_caroli
ENSG00000108771	DHX58	99	33.129	MGP_CAROLIEiJ_G0025893	Ddx58	73	30.603	Mus_caroli
ENSG00000108771	DHX58	100	83.974	MGP_CAROLIEiJ_G0017181	Dhx58	100	78.909	Mus_caroli
ENSG00000108771	DHX58	99	33.129	ENSMUSG00000040296	Ddx58	72	33.140	Mus_musculus
ENSG00000108771	DHX58	100	83.974	ENSMUSG00000017830	Dhx58	100	78.614	Mus_musculus
ENSG00000108771	DHX58	99	45.679	ENSMUSG00000026896	Ifih1	73	40.865	Mus_musculus
ENSG00000108771	DHX58	100	83.974	MGP_PahariEiJ_G0018311	Dhx58	100	77.876	Mus_pahari
ENSG00000108771	DHX58	99	45.679	MGP_PahariEiJ_G0025045	Ifih1	73	40.865	Mus_pahari
ENSG00000108771	DHX58	99	33.129	MGP_PahariEiJ_G0024016	Ddx58	61	32.090	Mus_pahari
ENSG00000108771	DHX58	100	83.974	MGP_SPRETEiJ_G0018024	Dhx58	100	78.909	Mus_spretus
ENSG00000108771	DHX58	99	45.679	MGP_SPRETEiJ_G0024516	Ifih1	73	40.865	Mus_spretus
ENSG00000108771	DHX58	100	32.822	MGP_SPRETEiJ_G0026842	Ddx58	72	32.755	Mus_spretus
ENSG00000108771	DHX58	99	34.139	ENSMPUG00000004319	DDX58	68	32.322	Mustela_putorius_furo
ENSG00000108771	DHX58	100	89.103	ENSMPUG00000010568	DHX58	100	82.769	Mustela_putorius_furo
ENSG00000108771	DHX58	96	48.718	ENSMPUG00000000564	IFIH1	70	40.802	Mustela_putorius_furo
ENSG00000108771	DHX58	95	37.755	ENSMLUG00000003041	DDX58	73	31.152	Myotis_lucifugus
ENSG00000108771	DHX58	99	89.677	ENSMLUG00000012001	DHX58	100	82.966	Myotis_lucifugus
ENSG00000108771	DHX58	99	48.765	ENSMLUG00000009505	IFIH1	70	40.699	Myotis_lucifugus
ENSG00000108771	DHX58	99	85.806	ENSNGAG00000017107	Dhx58	100	78.909	Nannospalax_galili
ENSG00000108771	DHX58	95	39.796	ENSNGAG00000003642	Ddx58	73	31.178	Nannospalax_galili
ENSG00000108771	DHX58	99	47.531	ENSNGAG00000012752	Ifih1	74	40.166	Nannospalax_galili
ENSG00000108771	DHX58	98	53.247	ENSNBRG00000018263	dhx58	99	47.198	Neolamprologus_brichardi
ENSG00000108771	DHX58	98	47.500	ENSNBRG00000014585	ifih1	76	39.205	Neolamprologus_brichardi
ENSG00000108771	DHX58	98	51.948	ENSNBRG00000018515	dhx58	99	46.120	Neolamprologus_brichardi
ENSG00000108771	DHX58	100	96.970	ENSNLEG00000026691	DHX58	100	84.661	Nomascus_leucogenys
ENSG00000108771	DHX58	99	49.383	ENSNLEG00000026782	IFIH1	73	41.004	Nomascus_leucogenys
ENSG00000108771	DHX58	98	50.000	ENSMEUG00000003310	IFIH1	69	36.606	Notamacropus_eugenii
ENSG00000108771	DHX58	99	72.258	ENSMEUG00000005569	DHX58	100	67.115	Notamacropus_eugenii
ENSG00000108771	DHX58	95	43.810	ENSOPRG00000015760	IFIH1	62	38.640	Ochotona_princeps
ENSG00000108771	DHX58	100	87.821	ENSOPRG00000000753	DHX58	100	78.761	Ochotona_princeps
ENSG00000108771	DHX58	100	85.897	ENSODEG00000017902	DHX58	100	80.236	Octodon_degus
ENSG00000108771	DHX58	97	36.076	ENSODEG00000015750	DDX58	72	30.848	Octodon_degus
ENSG00000108771	DHX58	99	50.000	ENSODEG00000013586	IFIH1	74	41.103	Octodon_degus
ENSG00000108771	DHX58	99	45.806	ENSONIG00000001090	dhx58	99	37.664	Oreochromis_niloticus
ENSG00000108771	DHX58	97	47.500	ENSONIG00000008901	ifih1	70	38.952	Oreochromis_niloticus
ENSG00000108771	DHX58	84	48.837	ENSONIG00000001101	-	99	37.931	Oreochromis_niloticus
ENSG00000108771	DHX58	97	37.888	ENSOANG00000012131	DDX58	86	32.904	Ornithorhynchus_anatinus
ENSG00000108771	DHX58	100	61.616	ENSOANG00000030614	-	91	61.607	Ornithorhynchus_anatinus
ENSG00000108771	DHX58	99	50.625	ENSOANG00000006194	IFIH1	64	43.230	Ornithorhynchus_anatinus
ENSG00000108771	DHX58	99	48.765	ENSOCUG00000002863	IFIH1	70	41.528	Oryctolagus_cuniculus
ENSG00000108771	DHX58	100	88.462	ENSOCUG00000013278	DHX58	100	83.186	Oryctolagus_cuniculus
ENSG00000108771	DHX58	99	33.742	ENSOCUG00000004710	DDX58	77	31.169	Oryctolagus_cuniculus
ENSG00000108771	DHX58	100	43.711	ENSORLG00000016902	ifih1	71	39.424	Oryzias_latipes
ENSG00000108771	DHX58	99	54.487	ENSORLG00000003825	dhx58	99	47.801	Oryzias_latipes
ENSG00000108771	DHX58	100	43.711	ENSORLG00020022369	ifih1	71	39.368	Oryzias_latipes_hni
ENSG00000108771	DHX58	99	54.487	ENSORLG00020008521	dhx58	99	47.654	Oryzias_latipes_hni
ENSG00000108771	DHX58	100	43.396	ENSORLG00015017957	ifih1	71	39.080	Oryzias_latipes_hsok
ENSG00000108771	DHX58	99	54.487	ENSORLG00015022015	dhx58	99	47.654	Oryzias_latipes_hsok
ENSG00000108771	DHX58	98	53.896	ENSOMEG00000023026	dhx58	96	47.300	Oryzias_melastigma
ENSG00000108771	DHX58	96	54.967	ENSOMEG00000023054	dhx58	99	46.210	Oryzias_melastigma
ENSG00000108771	DHX58	100	43.396	ENSOMEG00000002513	ifih1	71	38.506	Oryzias_melastigma
ENSG00000108771	DHX58	99	50.617	ENSOGAG00000012611	IFIH1	70	41.061	Otolemur_garnettii
ENSG00000108771	DHX58	99	34.049	ENSOGAG00000010536	DDX58	73	32.328	Otolemur_garnettii
ENSG00000108771	DHX58	100	91.026	ENSOGAG00000025321	DHX58	99	85.672	Otolemur_garnettii
ENSG00000108771	DHX58	96	51.282	ENSOARG00000006142	IFIH1	70	41.061	Ovis_aries
ENSG00000108771	DHX58	100	89.744	ENSOARG00000018383	DHX58	100	82.966	Ovis_aries
ENSG00000108771	DHX58	99	32.012	ENSOARG00000014731	DDX58	72	30.229	Ovis_aries
ENSG00000108771	DHX58	99	49.383	ENSPPAG00000038665	IFIH1	70	41.004	Pan_paniscus
ENSG00000108771	DHX58	100	98.820	ENSPPAG00000031118	DHX58	100	98.820	Pan_paniscus
ENSG00000108771	DHX58	95	37.755	ENSPPAG00000041750	DDX58	73	32.184	Pan_paniscus
ENSG00000108771	DHX58	99	33.837	ENSPPRG00000010161	DDX58	73	31.624	Panthera_pardus
ENSG00000108771	DHX58	100	45.597	ENSPPRG00000024685	IFIH1	70	40.725	Panthera_pardus
ENSG00000108771	DHX58	99	89.032	ENSPPRG00000004933	DHX58	99	84.490	Panthera_pardus
ENSG00000108771	DHX58	99	33.837	ENSPTIG00000015345	DDX58	73	31.624	Panthera_tigris_altaica
ENSG00000108771	DHX58	99	89.032	ENSPTIG00000007982	DHX58	99	84.786	Panthera_tigris_altaica
ENSG00000108771	DHX58	100	45.597	ENSPTIG00000019898	IFIH1	69	40.725	Panthera_tigris_altaica
ENSG00000108771	DHX58	99	49.383	ENSPTRG00000012582	IFIH1	70	41.004	Pan_troglodytes
ENSG00000108771	DHX58	95	37.755	ENSPTRG00000020844	DDX58	73	32.184	Pan_troglodytes
ENSG00000108771	DHX58	100	98.968	ENSPTRG00000009191	DHX58	100	98.968	Pan_troglodytes
ENSG00000108771	DHX58	100	98.077	ENSPANG00000021475	DHX58	100	96.165	Papio_anubis
ENSG00000108771	DHX58	99	49.383	ENSPANG00000023890	IFIH1	66	41.630	Papio_anubis
ENSG00000108771	DHX58	95	38.776	ENSPANG00000025269	DDX58	73	32.189	Papio_anubis
ENSG00000108771	DHX58	99	34.154	ENSPKIG00000017174	DDX58	73	31.609	Paramormyrops_kingsleyae
ENSG00000108771	DHX58	99	56.129	ENSPKIG00000020140	dhx58	98	49.275	Paramormyrops_kingsleyae
ENSG00000108771	DHX58	96	49.682	ENSPKIG00000001054	ifih1	71	41.159	Paramormyrops_kingsleyae
ENSG00000108771	DHX58	99	32.515	ENSPSIG00000013490	DDX58	73	30.216	Pelodiscus_sinensis
ENSG00000108771	DHX58	99	60.645	ENSPSIG00000016525	DHX58	100	51.245	Pelodiscus_sinensis
ENSG00000108771	DHX58	98	49.375	ENSPSIG00000007364	IFIH1	69	40.935	Pelodiscus_sinensis
ENSG00000108771	DHX58	97	47.468	ENSPMGG00000006236	ifih1	96	36.364	Periophthalmus_magnuspinnatus
ENSG00000108771	DHX58	99	53.205	ENSPMGG00000010442	dhx58	99	47.507	Periophthalmus_magnuspinnatus
ENSG00000108771	DHX58	95	37.755	ENSPEMG00000012372	Ddx58	73	31.322	Peromyscus_maniculatus_bairdii
ENSG00000108771	DHX58	100	83.974	ENSPEMG00000018681	Dhx58	100	79.204	Peromyscus_maniculatus_bairdii
ENSG00000108771	DHX58	99	46.914	ENSPEMG00000014586	Ifih1	73	40.782	Peromyscus_maniculatus_bairdii
ENSG00000108771	DHX58	82	35.192	ENSPMAG00000009697	DDX58	98	35.192	Petromyzon_marinus
ENSG00000108771	DHX58	72	50.000	ENSPMAG00000007346	-	99	39.431	Petromyzon_marinus
ENSG00000108771	DHX58	98	35.669	ENSPCIG00000029320	RIG-I	73	31.766	Phascolarctos_cinereus
ENSG00000108771	DHX58	98	50.000	ENSPCIG00000030338	IFIH1	76	41.069	Phascolarctos_cinereus
ENSG00000108771	DHX58	99	74.839	ENSPCIG00000020229	LGP2	100	68.045	Phascolarctos_cinereus
ENSG00000108771	DHX58	98	46.541	ENSPFOG00000017223	ifih1	71	38.649	Poecilia_formosa
ENSG00000108771	DHX58	99	55.128	ENSPFOG00000011777	dhx58	99	47.445	Poecilia_formosa
ENSG00000108771	DHX58	98	46.541	ENSPLAG00000000949	ifih1	71	38.793	Poecilia_latipinna
ENSG00000108771	DHX58	99	55.128	ENSPLAG00000021657	dhx58	99	47.445	Poecilia_latipinna
ENSG00000108771	DHX58	98	46.541	ENSPMEG00000016070	ifih1	71	38.649	Poecilia_mexicana
ENSG00000108771	DHX58	99	55.128	ENSPMEG00000011404	dhx58	99	47.445	Poecilia_mexicana
ENSG00000108771	DHX58	98	44.654	ENSPREG00000007796	ifih1	71	38.594	Poecilia_reticulata
ENSG00000108771	DHX58	99	54.487	ENSPREG00000010240	dhx58	99	47.591	Poecilia_reticulata
ENSG00000108771	DHX58	95	37.755	ENSPPYG00000019149	DDX58	77	32.323	Pongo_abelii
ENSG00000108771	DHX58	99	48.765	ENSPPYG00000012887	IFIH1	70	40.725	Pongo_abelii
ENSG00000108771	DHX58	55	34.328	ENSPCAG00000016086	-	51	34.328	Procavia_capensis
ENSG00000108771	DHX58	82	86.992	ENSPCAG00000016244	DHX58	90	86.992	Procavia_capensis
ENSG00000108771	DHX58	99	48.765	ENSPCAG00000007680	IFIH1	67	37.838	Procavia_capensis
ENSG00000108771	DHX58	100	91.026	ENSPCOG00000021497	DHX58	100	85.251	Propithecus_coquereli
ENSG00000108771	DHX58	95	37.755	ENSPCOG00000027117	DDX58	95	31.361	Propithecus_coquereli
ENSG00000108771	DHX58	99	48.765	ENSPCOG00000021673	IFIH1	70	40.865	Propithecus_coquereli
ENSG00000108771	DHX58	100	85.350	ENSPVAG00000003855	DHX58	99	83.186	Pteropus_vampyrus
ENSG00000108771	DHX58	99	33.544	ENSPVAG00000009207	DDX58	74	30.615	Pteropus_vampyrus
ENSG00000108771	DHX58	99	43.478	ENSPVAG00000002643	IFIH1	70	37.622	Pteropus_vampyrus
ENSG00000108771	DHX58	98	54.545	ENSPNYG00000010709	dhx58	99	56.085	Pundamilia_nyererei
ENSG00000108771	DHX58	98	47.500	ENSPNYG00000002971	ifih1	71	39.062	Pundamilia_nyererei
ENSG00000108771	DHX58	98	51.948	ENSPNYG00000010782	dhx58	99	45.735	Pundamilia_nyererei
ENSG00000108771	DHX58	99	34.985	ENSPNAG00000002347	-	73	33.047	Pygocentrus_nattereri
ENSG00000108771	DHX58	97	48.734	ENSPNAG00000023802	ifih1	67	41.643	Pygocentrus_nattereri
ENSG00000108771	DHX58	99	57.051	ENSPNAG00000028648	dhx58	99	49.854	Pygocentrus_nattereri
ENSG00000108771	DHX58	99	46.296	ENSRNOG00000006227	Ifih1	70	40.167	Rattus_norvegicus
ENSG00000108771	DHX58	95	37.895	ENSRNOG00000006384	Ddx58	55	32.335	Rattus_norvegicus
ENSG00000108771	DHX58	100	83.974	ENSRNOG00000018247	Dhx58	100	79.204	Rattus_norvegicus
ENSG00000108771	DHX58	95	38.776	ENSRBIG00000040257	DDX58	94	32.615	Rhinopithecus_bieti
ENSG00000108771	DHX58	99	49.383	ENSRBIG00000029188	IFIH1	68	41.485	Rhinopithecus_bieti
ENSG00000108771	DHX58	100	96.795	ENSRBIG00000028906	DHX58	100	95.723	Rhinopithecus_bieti
ENSG00000108771	DHX58	100	97.436	ENSRROG00000035891	DHX58	100	95.238	Rhinopithecus_roxellana
ENSG00000108771	DHX58	99	49.383	ENSRROG00000030959	IFIH1	70	41.004	Rhinopithecus_roxellana
ENSG00000108771	DHX58	95	38.776	ENSRROG00000029512	DDX58	73	32.615	Rhinopithecus_roxellana
ENSG00000108771	DHX58	100	45.597	ENSSBOG00000026205	IFIH1	70	41.562	Saimiri_boliviensis_boliviensis
ENSG00000108771	DHX58	95	39.796	ENSSBOG00000030627	DDX58	72	32.475	Saimiri_boliviensis_boliviensis
ENSG00000108771	DHX58	100	93.939	ENSSBOG00000020589	DHX58	100	91.003	Saimiri_boliviensis_boliviensis
ENSG00000108771	DHX58	98	50.000	ENSSHAG00000017981	IFIH1	69	41.102	Sarcophilus_harrisii
ENSG00000108771	DHX58	100	70.861	ENSSHAG00000006130	DHX58	100	67.012	Sarcophilus_harrisii
ENSG00000108771	DHX58	100	56.688	ENSSFOG00015023124	dhx58	99	50.074	Scleropages_formosus
ENSG00000108771	DHX58	97	49.367	ENSSFOG00015022705	ifih1	76	40.778	Scleropages_formosus
ENSG00000108771	DHX58	99	34.877	ENSSFOG00015017386	ddx58	72	32.281	Scleropages_formosus
ENSG00000108771	DHX58	98	55.195	ENSSMAG00000007427	dhx58	99	48.164	Scophthalmus_maximus
ENSG00000108771	DHX58	97	48.101	ENSSMAG00000012345	ifih1	67	45.357	Scophthalmus_maximus
ENSG00000108771	DHX58	97	46.835	ENSSDUG00000019000	ifih1	70	39.250	Seriola_dumerili
ENSG00000108771	DHX58	99	56.410	ENSSDUG00000022971	dhx58	99	49.048	Seriola_dumerili
ENSG00000108771	DHX58	99	55.769	ENSSLDG00000017659	dhx58	99	48.316	Seriola_lalandi_dorsalis
ENSG00000108771	DHX58	97	46.835	ENSSLDG00000016351	ifih1	70	39.394	Seriola_lalandi_dorsalis
ENSG00000108771	DHX58	92	72.340	ENSSARG00000002192	DHX58	78	84.426	Sorex_araneus
ENSG00000108771	DHX58	99	32.704	ENSSPUG00000002608	DDX58	73	30.029	Sphenodon_punctatus
ENSG00000108771	DHX58	99	62.987	ENSSPUG00000012993	DHX58	99	54.074	Sphenodon_punctatus
ENSG00000108771	DHX58	99	50.000	ENSSPUG00000017377	IFIH1	70	41.252	Sphenodon_punctatus
ENSG00000108771	DHX58	99	53.205	ENSSPAG00000006485	dhx58	99	47.291	Stegastes_partitus
ENSG00000108771	DHX58	97	48.734	ENSSPAG00000000528	ifih1	77	40.000	Stegastes_partitus
ENSG00000108771	DHX58	95	37.895	ENSSSCG00000030408	DDX58	86	31.089	Sus_scrofa
ENSG00000108771	DHX58	100	89.103	ENSSSCG00000017416	DHX58	100	82.379	Sus_scrofa
ENSG00000108771	DHX58	96	50.641	ENSSSCG00000015897	IFIH1	74	40.915	Sus_scrofa
ENSG00000108771	DHX58	97	30.323	ENSTGUG00000001516	DDX58	73	30.059	Taeniopygia_guttata
ENSG00000108771	DHX58	100	56.623	ENSTGUG00000002516	DHX58	100	52.537	Taeniopygia_guttata
ENSG00000108771	DHX58	99	47.826	ENSTGUG00000006914	IFIH1	71	39.310	Taeniopygia_guttata
ENSG00000108771	DHX58	98	50.000	ENSTRUG00000001413	ifih1	73	40.230	Takifugu_rubripes
ENSG00000108771	DHX58	99	55.769	ENSTRUG00000015710	dhx58	99	47.299	Takifugu_rubripes
ENSG00000108771	DHX58	100	46.708	ENSTNIG00000016500	ifih1	69	39.455	Tetraodon_nigroviridis
ENSG00000108771	DHX58	97	54.605	ENSTNIG00000011713	dhx58	98	47.731	Tetraodon_nigroviridis
ENSG00000108771	DHX58	99	49.383	ENSTBEG00000005625	IFIH1	60	39.781	Tupaia_belangeri
ENSG00000108771	DHX58	90	86.957	ENSTBEG00000005427	DHX58	81	91.057	Tupaia_belangeri
ENSG00000108771	DHX58	99	31.077	ENSTTRG00000016993	DDX58	86	30.029	Tursiops_truncatus
ENSG00000108771	DHX58	99	51.852	ENSTTRG00000013780	IFIH1	70	37.291	Tursiops_truncatus
ENSG00000108771	DHX58	100	87.179	ENSTTRG00000006650	DHX58	100	82.673	Tursiops_truncatus
ENSG00000108771	DHX58	99	34.663	ENSUAMG00000020703	DDX58	73	32.421	Ursus_americanus
ENSG00000108771	DHX58	100	45.283	ENSUAMG00000015811	IFIH1	74	41.144	Ursus_americanus
ENSG00000108771	DHX58	100	87.821	ENSUAMG00000024348	DHX58	100	82.353	Ursus_americanus
ENSG00000108771	DHX58	99	34.139	ENSUMAG00000005813	DDX58	77	32.189	Ursus_maritimus
ENSG00000108771	DHX58	100	87.821	ENSUMAG00000023000	DHX58	100	77.424	Ursus_maritimus
ENSG00000108771	DHX58	100	45.283	ENSUMAG00000012031	IFIH1	67	41.314	Ursus_maritimus
ENSG00000108771	DHX58	90	80.435	ENSVPAG00000005442	-	63	81.319	Vicugna_pacos
ENSG00000108771	DHX58	99	46.386	ENSVPAG00000010823	IFIH1	82	38.248	Vicugna_pacos
ENSG00000108771	DHX58	99	33.535	ENSVVUG00000021149	DDX58	78	31.586	Vulpes_vulpes
ENSG00000108771	DHX58	100	87.821	ENSVVUG00000020914	DHX58	100	80.378	Vulpes_vulpes
ENSG00000108771	DHX58	96	47.436	ENSVVUG00000018569	IFIH1	71	40.969	Vulpes_vulpes
ENSG00000108771	DHX58	99	50.617	ENSXETG00000013176	ifih1	69	41.954	Xenopus_tropicalis
ENSG00000108771	DHX58	99	34.810	ENSXETG00000009200	ddx58	73	30.636	Xenopus_tropicalis
ENSG00000108771	DHX58	100	60.510	ENSXETG00000002302	dhx58	98	49.701	Xenopus_tropicalis
ENSG00000108771	DHX58	98	46.541	ENSXCOG00000019338	ifih1	72	39.511	Xiphophorus_couchianus
ENSG00000108771	DHX58	99	55.128	ENSXMAG00000008899	dhx58	99	47.801	Xiphophorus_maculatus
ENSG00000108771	DHX58	98	46.541	ENSXMAG00000011536	ifih1	72	39.511	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0003677	DNA binding	-	IEA	Function
GO:0003725	double-stranded RNA binding	18411269.	IDA	Function
GO:0003727	single-stranded RNA binding	18411269.	IDA	Function
GO:0004386	helicase activity	-	IEA	Function
GO:0005515	protein binding	17190814.19403670.21791617.21903422.25340845.	IPI	Function
GO:0005524	ATP binding	-	IEA	Function
GO:0005737	cytoplasm	-	IEA	Component
GO:0008270	zinc ion binding	19278996.	IDA	Function
GO:0009615	response to virus	-	ISS	Process
GO:0009617	response to bacterium	-	IEA	Process
GO:0016032	viral process	-	IEA	Process
GO:0032480	negative regulation of type I interferon production	21525357.	IDA	Process
GO:0032481	positive regulation of type I interferon production	-	ISS	Process
GO:0039534	negative regulation of MDA-5 signaling pathway	21187438.	IMP	Process
GO:0039536	negative regulation of RIG-I signaling pathway	18411269.	IDA	Process
GO:0039536	negative regulation of RIG-I signaling pathway	21187438.	IMP	Process
GO:0045087	innate immune response	-	IEA	Process
GO:0045088	regulation of innate immune response	18411269.	IDA	Process
GO:0045824	negative regulation of innate immune response	21525357.	IDA	Process
GO:0051607	defense response to virus	-	IEA	Process
GO:1900245	positive regulation of MDA-5 signaling pathway	-	ISS	Process
GO:1900246	positive regulation of RIG-I signaling pathway	-	ISS	Process