EuRBPDB

Description

RBDs

Expression

Transcripts

Gene Model

Phenotypes

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000110060 (Gene tree)
Gene ID: 83480
Gene Symbol: PUS3
Alias: FKSG32
Full Name: pseudouridine synthase 3
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Minus strand
Length: 9,885 bases
Position: chr11:125,893,485-125,903,369
Accession: 25461
RBP type: canonical RBP
Summary: The protein encoded by this gene catalyzes the formation of tRNA pseudouridine from tRNA uridine at position 39 in the anticodon stem and loop of transfer RNAs. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2012]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000227474	PseudoU_synth_1	PF01416.20	2e-32	1	1
ENSP00000432386	PseudoU_synth_1	PF01416.20	2e-32	1	1
ENSP00000481536	PseudoU_synth_1	PF01416.20	1.6e-31	1	1

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000529801	PUS3-202	579	-	ENSP00000437077	105 (aa)	-	E9PNY6
ENST00000613398	PUS3-205	1419	XM_024448706	ENSP00000481536	273 (aa)	XP_024304474	A0A087WY59
ENST00000534158	PUS3-204	605	XM_005271688	ENSP00000432272	169 (aa)	XP_005271745	E9PRI9
ENST00000530811	PUS3-203	1792	-	ENSP00000432386	481 (aa)	-	Q9BZE2
ENST00000227474	PUS3-201	1843	-	ENSP00000227474	481 (aa)	-	Q9BZE2

Gene Model

Click here to download ENSG00000110060's gene model file

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000110060	Aspartate Aminotransferases	6.673e-005	-

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000110060's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000110060	PUS3	93	56.173	ENSAPOG00000019483	pus3	93	53.596	Acanthochromis_polyacanthus
ENSG00000110060	PUS3	99	91.544	ENSAMEG00000000144	PUS3	99	90.625	Ailuropoda_melanoleuca
ENSG00000110060	PUS3	98	55.556	ENSACIG00000024479	pus3	99	57.278	Amphilophus_citrinellus
ENSG00000110060	PUS3	94	49.198	ENSAOCG00000006589	pus3	91	50.549	Amphiprion_ocellaris
ENSG00000110060	PUS3	94	50.000	ENSAPEG00000014617	pus3	91	50.885	Amphiprion_percula
ENSG00000110060	PUS3	94	54.598	ENSATEG00000022731	pus3	90	53.244	Anabas_testudineus
ENSG00000110060	PUS3	97	62.286	ENSAPLG00000013285	PUS3	98	69.794	Anas_platyrhynchos
ENSG00000110060	PUS3	96	65.868	ENSACAG00000000186	PUS3	99	66.958	Anolis_carolinensis
ENSG00000110060	PUS3	100	95.604	ENSANAG00000035614	PUS3	100	94.802	Aotus_nancymaae
ENSG00000110060	PUS3	95	49.462	ENSACLG00000007356	pus3	92	50.442	Astatotilapia_calliptera
ENSG00000110060	PUS3	93	51.955	ENSAMXG00000019534	pus3	93	51.282	Astyanax_mexicanus
ENSG00000110060	PUS3	100	90.476	ENSBTAG00000014339	PUS3	100	88.797	Bos_taurus
ENSG00000110060	PUS3	75	39.695	WBGene00006473	tag-124	95	33.831	Caenorhabditis_elegans
ENSG00000110060	PUS3	100	95.238	ENSCJAG00000046645	PUS3	100	94.387	Callithrix_jacchus
ENSG00000110060	PUS3	99	89.706	ENSCAFG00000010534	PUS3	99	88.542	Canis_familiaris
ENSG00000110060	PUS3	99	89.706	ENSCAFG00020010659	PUS3	99	88.542	Canis_lupus_dingo
ENSG00000110060	PUS3	99	88.971	ENSCHIG00000012260	PUS3	99	87.318	Capra_hircus
ENSG00000110060	PUS3	100	90.476	ENSTSYG00000014744	PUS3	99	90.021	Carlito_syrichta
ENSG00000110060	PUS3	100	83.883	ENSCAPG00000012231	PUS3	100	83.576	Cavia_aperea
ENSG00000110060	PUS3	100	83.883	ENSCPOG00000032587	PUS3	100	83.576	Cavia_porcellus
ENSG00000110060	PUS3	100	95.238	ENSCCAG00000035999	PUS3	99	94.351	Cebus_capucinus
ENSG00000110060	PUS3	100	97.802	ENSCATG00000043123	PUS3	100	97.297	Cercocebus_atys
ENSG00000110060	PUS3	100	87.912	ENSCLAG00000014947	PUS3	100	86.279	Chinchilla_lanigera
ENSG00000110060	PUS3	100	97.802	ENSCSAG00000002281	PUS3	100	97.297	Chlorocebus_sabaeus
ENSG00000110060	PUS3	100	81.905	ENSCHOG00000008442	PUS3	99	87.533	Choloepus_hoffmanni
ENSG00000110060	PUS3	99	71.223	ENSCPBG00000011173	PUS3	98	71.223	Chrysemys_picta_bellii
ENSG00000110060	PUS3	61	36.391	ENSCING00000009062	-	63	35.780	Ciona_intestinalis
ENSG00000110060	PUS3	85	40.789	ENSCSAVG00000002211	-	95	34.813	Ciona_savignyi
ENSG00000110060	PUS3	100	97.041	ENSCANG00000038729	PUS3	100	96.258	Colobus_angolensis_palliatus
ENSG00000110060	PUS3	100	86.861	ENSCGRG00001019842	Pus3	100	86.307	Cricetulus_griseus_chok1gshd
ENSG00000110060	PUS3	100	86.131	ENSCGRG00000010155	Pus3	100	85.892	Cricetulus_griseus_crigri
ENSG00000110060	PUS3	92	54.658	ENSCSEG00000007948	pus3	89	52.681	Cynoglossus_semilaevis
ENSG00000110060	PUS3	94	46.703	ENSCVAG00000022150	pus3	91	50.885	Cyprinodon_variegatus
ENSG00000110060	PUS3	94	56.024	ENSDARG00000028976	pus3	93	54.241	Danio_rerio
ENSG00000110060	PUS3	99	88.561	ENSDNOG00000040719	PUS3	100	86.128	Dasypus_novemcinctus
ENSG00000110060	PUS3	100	84.762	ENSDORG00000001819	Pus3	99	85.000	Dipodomys_ordii
ENSG00000110060	PUS3	99	48.214	FBgn0034703	CG3045	90	39.368	Drosophila_melanogaster
ENSG00000110060	PUS3	100	86.813	ENSETEG00000013067	PUS3	99	80.249	Echinops_telfairi
ENSG00000110060	PUS3	91	48.408	ENSEBUG00000002154	pus3	65	48.571	Eptatretus_burgeri
ENSG00000110060	PUS3	100	89.011	ENSEASG00005023003	PUS3	100	88.981	Equus_asinus_asinus
ENSG00000110060	PUS3	100	89.189	ENSECAG00000007581	PUS3	100	89.189	Equus_caballus
ENSG00000110060	PUS3	100	86.081	ENSEEUG00000010543	PUS3	100	83.992	Erinaceus_europaeus
ENSG00000110060	PUS3	94	59.302	ENSELUG00000004425	pus3	92	55.125	Esox_lucius
ENSG00000110060	PUS3	99	91.176	ENSFCAG00000005340	PUS3	99	89.375	Felis_catus
ENSG00000110060	PUS3	97	64.842	ENSFALG00000005159	PUS3	98	64.211	Ficedula_albicollis
ENSG00000110060	PUS3	100	86.447	ENSFDAG00000020745	PUS3	100	85.447	Fukomys_damarensis
ENSG00000110060	PUS3	97	48.352	ENSFHEG00000010984	pus3	85	50.985	Fundulus_heteroclitus
ENSG00000110060	PUS3	94	52.976	ENSGMOG00000004534	pus3	95	52.403	Gadus_morhua
ENSG00000110060	PUS3	97	64.000	ENSGALG00000000962	PUS3	97	67.174	Gallus_gallus
ENSG00000110060	PUS3	92	48.603	ENSGAFG00000005615	pus3	92	50.435	Gambusia_affinis
ENSG00000110060	PUS3	95	51.765	ENSGACG00000002125	pus3	90	52.294	Gasterosteus_aculeatus
ENSG00000110060	PUS3	99	70.863	ENSGAGG00000000160	PUS3	99	69.715	Gopherus_agassizii
ENSG00000110060	PUS3	100	98.901	ENSGGOG00000015047	PUS3	100	98.545	Gorilla_gorilla
ENSG00000110060	PUS3	94	49.457	ENSHBUG00000016532	pus3	92	50.221	Haplochromis_burtoni
ENSG00000110060	PUS3	99	80.515	ENSHGLG00000006599	-	97	78.958	Heterocephalus_glaber_female
ENSG00000110060	PUS3	100	72.527	ENSHGLG00000016285	-	100	72.527	Heterocephalus_glaber_female
ENSG00000110060	PUS3	100	77.289	ENSHGLG00000018861	-	100	74.012	Heterocephalus_glaber_female
ENSG00000110060	PUS3	100	67.456	ENSHGLG00000015753	-	82	76.012	Heterocephalus_glaber_female
ENSG00000110060	PUS3	100	88.278	ENSHGLG00000000565	PUS3	100	86.279	Heterocephalus_glaber_female
ENSG00000110060	PUS3	100	75.238	ENSHGLG00100008656	-	99	82.484	Heterocephalus_glaber_male
ENSG00000110060	PUS3	100	73.993	ENSHGLG00100002139	-	100	74.359	Heterocephalus_glaber_male
ENSG00000110060	PUS3	100	75.148	ENSHGLG00100007519	-	96	70.625	Heterocephalus_glaber_male
ENSG00000110060	PUS3	100	83.883	ENSHGLG00100014825	-	100	80.665	Heterocephalus_glaber_male
ENSG00000110060	PUS3	100	77.289	ENSHGLG00100011339	-	100	70.894	Heterocephalus_glaber_male
ENSG00000110060	PUS3	100	72.189	ENSHGLG00100002435	-	100	76.552	Heterocephalus_glaber_male
ENSG00000110060	PUS3	93	54.819	ENSHCOG00000015705	pus3	92	51.501	Hippocampus_comes
ENSG00000110060	PUS3	95	54.144	ENSIPUG00000000105	pus3	90	52.116	Ictalurus_punctatus
ENSG00000110060	PUS3	100	87.912	ENSSTOG00000003721	PUS3	100	87.734	Ictidomys_tridecemlineatus
ENSG00000110060	PUS3	100	86.447	ENSJJAG00000011306	Pus3	99	84.823	Jaculus_jaculus
ENSG00000110060	PUS3	94	46.809	ENSKMAG00000016715	pus3	91	49.561	Kryptolebias_marmoratus
ENSG00000110060	PUS3	90	55.670	ENSLBEG00000004143	pus3	91	50.455	Labrus_bergylta
ENSG00000110060	PUS3	96	61.777	ENSLACG00000011161	PUS3	97	61.284	Latimeria_chalumnae
ENSG00000110060	PUS3	93	50.811	ENSLOCG00000011922	pus3	97	50.866	Lepisosteus_oculatus
ENSG00000110060	PUS3	100	90.842	ENSLAFG00000000535	PUS3	100	88.358	Loxodonta_africana
ENSG00000110060	PUS3	100	97.436	ENSMFAG00000041002	PUS3	99	96.653	Macaca_fascicularis
ENSG00000110060	PUS3	100	97.436	ENSMMUG00000041875	PUS3	99	96.653	Macaca_mulatta
ENSG00000110060	PUS3	100	97.802	ENSMNEG00000045347	PUS3	99	96.862	Macaca_nemestrina
ENSG00000110060	PUS3	100	97.436	ENSMLEG00000029053	PUS3	100	97.089	Mandrillus_leucophaeus
ENSG00000110060	PUS3	94	49.727	ENSMAMG00000016741	pus3	91	51.441	Mastacembelus_armatus
ENSG00000110060	PUS3	94	50.000	ENSMZEG00005015950	pus3	92	50.442	Maylandia_zebra
ENSG00000110060	PUS3	97	65.663	ENSMGAG00000000851	PUS3	99	70.153	Meleagris_gallopavo
ENSG00000110060	PUS3	100	85.766	ENSMAUG00000015873	Pus3	100	85.685	Mesocricetus_auratus
ENSG00000110060	PUS3	99	90.809	ENSMICG00000032941	PUS3	99	88.750	Microcebus_murinus
ENSG00000110060	PUS3	100	86.100	ENSMOCG00000004901	Pus3	100	86.100	Microtus_ochrogaster
ENSG00000110060	PUS3	94	57.055	ENSMMOG00000013909	pus3	90	54.273	Mola_mola
ENSG00000110060	PUS3	100	72.989	ENSMODG00000004222	PUS3	99	77.405	Monodelphis_domestica
ENSG00000110060	PUS3	94	56.627	ENSMALG00000022420	pus3	90	54.378	Monopterus_albus
ENSG00000110060	PUS3	100	86.861	MGP_CAROLIEiJ_G0031957	Pus3	99	88.924	Mus_caroli
ENSG00000110060	PUS3	100	84.211	ENSMUSG00000032103	Pus3	99	88.291	Mus_musculus
ENSG00000110060	PUS3	100	86.496	MGP_PahariEiJ_G0014822	Pus3	99	88.608	Mus_pahari
ENSG00000110060	PUS3	100	85.036	MGP_SPRETEiJ_G0033081	Pus3	99	87.975	Mus_spretus
ENSG00000110060	PUS3	99	90.809	ENSMPUG00000006568	PUS3	99	89.583	Mustela_putorius_furo
ENSG00000110060	PUS3	100	86.694	ENSMLUG00000030636	PUS3	100	86.694	Myotis_lucifugus
ENSG00000110060	PUS3	99	85.417	ENSNGAG00000013868	Pus3	100	85.417	Nannospalax_galili
ENSG00000110060	PUS3	94	48.649	ENSNBRG00000015864	pus3	93	49.890	Neolamprologus_brichardi
ENSG00000110060	PUS3	100	97.713	ENSNLEG00000007460	PUS3	100	97.713	Nomascus_leucogenys
ENSG00000110060	PUS3	98	72.515	ENSMEUG00000014040	PUS3	85	79.560	Notamacropus_eugenii
ENSG00000110060	PUS3	100	87.179	ENSOPRG00000007888	-	99	86.071	Ochotona_princeps
ENSG00000110060	PUS3	100	87.546	ENSODEG00000004280	PUS3	100	86.071	Octodon_degus
ENSG00000110060	PUS3	95	53.757	ENSONIG00000016224	pus3	98	52.632	Oreochromis_niloticus
ENSG00000110060	PUS3	100	66.860	ENSOANG00000000406	PUS3	98	67.653	Ornithorhynchus_anatinus
ENSG00000110060	PUS3	100	86.667	ENSOCUG00000004468	PUS3	93	86.837	Oryctolagus_cuniculus
ENSG00000110060	PUS3	94	48.370	ENSORLG00000008445	pus3	91	49.115	Oryzias_latipes
ENSG00000110060	PUS3	94	46.196	ENSORLG00020008847	pus3	98	46.680	Oryzias_latipes_hni
ENSG00000110060	PUS3	94	47.826	ENSORLG00015007438	pus3	98	47.510	Oryzias_latipes_hsok
ENSG00000110060	PUS3	94	51.724	ENSOMEG00000014321	pus3	93	51.106	Oryzias_melastigma
ENSG00000110060	PUS3	100	89.011	ENSOGAG00000008913	PUS3	100	88.981	Otolemur_garnettii
ENSG00000110060	PUS3	100	90.110	ENSOARG00000011870	PUS3	100	88.382	Ovis_aries
ENSG00000110060	PUS3	100	99.267	ENSPPAG00000025809	PUS3	100	98.960	Pan_paniscus
ENSG00000110060	PUS3	99	91.176	ENSPPRG00000005662	PUS3	99	89.167	Panthera_pardus
ENSG00000110060	PUS3	99	90.809	ENSPTIG00000001192	PUS3	99	88.958	Panthera_tigris_altaica
ENSG00000110060	PUS3	100	99.634	ENSPTRG00000004449	PUS3	100	99.168	Pan_troglodytes
ENSG00000110060	PUS3	100	97.436	ENSPANG00000013782	PUS3	100	97.089	Papio_anubis
ENSG00000110060	PUS3	94	48.045	ENSPKIG00000000646	pus3	93	50.985	Paramormyrops_kingsleyae
ENSG00000110060	PUS3	99	68.345	ENSPSIG00000013961	PUS3	99	67.886	Pelodiscus_sinensis
ENSG00000110060	PUS3	81	58.741	ENSPMGG00000000911	pus3	97	50.227	Periophthalmus_magnuspinnatus
ENSG00000110060	PUS3	100	86.861	ENSPEMG00000009602	Pus3	100	86.128	Peromyscus_maniculatus_bairdii
ENSG00000110060	PUS3	98	75.891	ENSPCIG00000010225	PUS3	97	78.104	Phascolarctos_cinereus
ENSG00000110060	PUS3	92	53.049	ENSPFOG00000009447	pus3	94	52.995	Poecilia_formosa
ENSG00000110060	PUS3	92	50.000	ENSPLAG00000023343	pus3	90	51.778	Poecilia_latipinna
ENSG00000110060	PUS3	92	50.000	ENSPMEG00000009870	pus3	90	51.778	Poecilia_mexicana
ENSG00000110060	PUS3	78	58.088	ENSPREG00000003179	pus3	56	61.149	Poecilia_reticulata
ENSG00000110060	PUS3	100	98.168	ENSPPYG00000004039	PUS3	100	97.921	Pongo_abelii
ENSG00000110060	PUS3	99	88.235	ENSPCAG00000000441	PUS3	100	86.667	Procavia_capensis
ENSG00000110060	PUS3	99	92.279	ENSPCOG00000019330	PUS3	99	90.625	Propithecus_coquereli
ENSG00000110060	PUS3	100	86.486	ENSPVAG00000002606	PUS3	100	86.486	Pteropus_vampyrus
ENSG00000110060	PUS3	94	49.457	ENSPNYG00000019615	pus3	92	50.221	Pundamilia_nyererei
ENSG00000110060	PUS3	93	52.514	ENSPNAG00000014541	pus3	89	52.796	Pygocentrus_nattereri
ENSG00000110060	PUS3	100	83.577	ENSRNOG00000012994	Pus3	99	83.857	Rattus_norvegicus
ENSG00000110060	PUS3	100	96.703	ENSRBIG00000044456	PUS3	100	95.634	Rhinopithecus_bieti
ENSG00000110060	PUS3	100	97.089	ENSRROG00000035245	PUS3	100	97.089	Rhinopithecus_roxellana
ENSG00000110060	PUS3	93	39.881	YFL001W	DEG1	71	43.284	Saccharomyces_cerevisiae
ENSG00000110060	PUS3	100	95.604	ENSSBOG00000022433	PUS3	100	94.595	Saimiri_boliviensis_boliviensis
ENSG00000110060	PUS3	100	75.273	ENSSHAG00000001382	PUS3	99	75.620	Sarcophilus_harrisii
ENSG00000110060	PUS3	91	61.146	ENSSFOG00015004850	pus3	92	53.812	Scleropages_formosus
ENSG00000110060	PUS3	94	48.421	ENSSMAG00000020340	pus3	91	50.435	Scophthalmus_maximus
ENSG00000110060	PUS3	92	51.366	ENSSDUG00000020825	pus3	90	51.220	Seriola_dumerili
ENSG00000110060	PUS3	92	50.273	ENSSLDG00000019932	pus3	90	50.998	Seriola_lalandi_dorsalis
ENSG00000110060	PUS3	100	79.048	ENSSARG00000013826	PUS3	100	83.758	Sorex_araneus
ENSG00000110060	PUS3	97	69.023	ENSSPUG00000001412	PUS3	98	69.023	Sphenodon_punctatus
ENSG00000110060	PUS3	94	54.601	ENSSPAG00000019221	pus3	92	53.364	Stegastes_partitus
ENSG00000110060	PUS3	99	88.971	ENSSSCG00000015222	PUS3	100	86.875	Sus_scrofa
ENSG00000110060	PUS3	93	66.049	ENSTGUG00000000778	-	98	68.287	Taeniopygia_guttata
ENSG00000110060	PUS3	94	50.000	ENSTRUG00000013050	pus3	95	49.778	Takifugu_rubripes
ENSG00000110060	PUS3	95	51.176	ENSTNIG00000004929	PUS3	90	49.771	Tetraodon_nigroviridis
ENSG00000110060	PUS3	95	48.108	ENSTNIG00000010307	pus3	93	50.773	Tetraodon_nigroviridis
ENSG00000110060	PUS3	100	78.107	ENSTBEG00000004382	PUS3	100	78.166	Tupaia_belangeri
ENSG00000110060	PUS3	100	91.941	ENSTTRG00000012167	PUS3	100	90.437	Tursiops_truncatus
ENSG00000110060	PUS3	99	91.912	ENSUAMG00000009297	PUS3	99	90.625	Ursus_americanus
ENSG00000110060	PUS3	99	92.279	ENSUMAG00000001795	PUS3	99	91.042	Ursus_maritimus
ENSG00000110060	PUS3	99	88.235	ENSVPAG00000001495	PUS3	99	87.500	Vicugna_pacos
ENSG00000110060	PUS3	99	89.706	ENSVVUG00000020152	PUS3	99	88.542	Vulpes_vulpes
ENSG00000110060	PUS3	95	56.886	ENSXETG00000024532	pus3	82	57.208	Xenopus_tropicalis
ENSG00000110060	PUS3	75	51.908	ENSXMAG00000025659	PUS3	52	57.372	Xiphophorus_maculatus
ENSG00000110060	PUS3	75	51.908	ENSXMAG00000025077	pus3	77	54.790	Xiphophorus_maculatus
ENSG00000110060	PUS3	75	51.908	ENSXMAG00000029934	pus3	77	54.627	Xiphophorus_maculatus
ENSG00000110060	PUS3	62	59.259	ENSXMAG00000025146	pus3	78	59.843	Xiphophorus_maculatus
ENSG00000110060	PUS3	92	53.750	ENSXMAG00000028016	pus3	95	51.106	Xiphophorus_maculatus
ENSG00000110060	PUS3	62	59.259	ENSXMAG00000028945	pus3	84	59.843	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0003723	RNA binding	-	IEA	Function
GO:0005634	nucleus	21873635.	IBA	Component
GO:0005737	cytoplasm	21873635.	IBA	Component
GO:0005829	cytosol	-	TAS	Component
GO:0006400	tRNA modification	-	TAS	Process
GO:0009982	pseudouridine synthase activity	27055666.	EXP	Function
GO:0009982	pseudouridine synthase activity	21873635.	IBA	Function
GO:0009982	pseudouridine synthase activity	27055666.	IMP	Function
GO:0031119	tRNA pseudouridine synthesis	21873635.	IBA	Process
GO:0031119	tRNA pseudouridine synthesis	27055666.	IMP	Process
GO:0106029	tRNA pseudouridine synthase activity	-	IEA	Function
GO:1990481	mRNA pseudouridine synthesis	21873635.	IBA	Process