EuRBPDB

Description

RBDs

RBPome

Literatures

Expression

Transcripts

Gene Model

Pathways

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000110107 (Gene tree)
Gene ID: 27339
Gene Symbol: PRPF19
Alias: UBOX4|NMP200|PSO4|hPSO4|SNEV|PRP19
Full Name: pre-mRNA processing factor 19
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Minus strand
Length: 16,043 bases
Position: chr11:60,890,547-60,906,589
Accession: 17896
RBP type: canonical RBP
Summary: PSO4 is the human homolog of yeast Pso4, a gene essential for cell survival and DNA repair (Beck et al., 2008 [PubMed 18263876]).[supplied by OMIM, Sep 2008]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000440266	Prp19	PF08606.11	6.9e-33	1	1
ENSP00000227524	Prp19	PF08606.11	2.1e-32	1	1
ENSP00000446259	Prp19	PF08606.11	6.8e-21	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
29431736	Capturing the interactome of newly transcribed RNA	NascentRICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	PolyT-RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
7680101	The yeast PRP19 protein is not tightly associated with small nuclear RNAs, but appears to associate with the spliceosome after binding of U2 to the pre-mRNA and prior to formation of the functional spliceosome.	Mol Cell Biol	1993 Mar	Tarn WY	-

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000535326	PRPF19-202	779	-	ENSP00000445435	119 (aa)	-	H0YGZ5
ENST00000539180	PRPF19-203	441	-	-	- (aa)	-	-
ENST00000539960	PRPF19-204	796	-	-	- (aa)	-	-
ENST00000541371	PRPF19-206	943	-	ENSP00000440266	252 (aa)	-	F5GY56
ENST00000546152	PRPF19-207	814	-	ENSP00000446259	104 (aa)	-	F5H2I0
ENST00000227524	PRPF19-201	2157	-	ENSP00000227524	504 (aa)	-	Q9UMS4
ENST00000540473	PRPF19-205	169	-	ENSP00000443031	45 (aa)	-	H0YGF3

Gene Model

Click here to download ENSG00000110107's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa03040	Spliceosome	KEGG
hsa04120	Ubiquitin mediated proteolysis	KEGG

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000110107's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000110107	PRPF19	100	88.571	ENSAPOG00000017823	prpf19	100	85.941	Acanthochromis_polyacanthus
ENSG00000110107	PRPF19	100	99.396	ENSAMEG00000007375	PRPF19	99	99.396	Ailuropoda_melanoleuca
ENSG00000110107	PRPF19	100	88.462	ENSACIG00000015876	prpf19	99	84.692	Amphilophus_citrinellus
ENSG00000110107	PRPF19	100	88.571	ENSAOCG00000020444	prpf19	100	85.941	Amphiprion_ocellaris
ENSG00000110107	PRPF19	100	88.571	ENSAPEG00000016076	prpf19	100	85.941	Amphiprion_percula
ENSG00000110107	PRPF19	100	88.571	ENSATEG00000008840	prpf19	100	85.941	Anabas_testudineus
ENSG00000110107	PRPF19	100	97.421	ENSACAG00000017797	PRPF19	100	97.421	Anolis_carolinensis
ENSG00000110107	PRPF19	100	100.000	ENSANAG00000021762	PRPF19	100	99.603	Aotus_nancymaae
ENSG00000110107	PRPF19	100	88.571	ENSACLG00000009416	prpf19	100	84.950	Astatotilapia_calliptera
ENSG00000110107	PRPF19	100	89.524	ENSAMXG00000011547	prpf19	100	85.743	Astyanax_mexicanus
ENSG00000110107	PRPF19	100	100.000	ENSBTAG00000014366	PRPF19	100	99.802	Bos_taurus
ENSG00000110107	PRPF19	100	51.923	WBGene00020423	prp-19	100	51.581	Caenorhabditis_elegans
ENSG00000110107	PRPF19	100	100.000	ENSCJAG00000016509	PRPF19	100	99.802	Callithrix_jacchus
ENSG00000110107	PRPF19	100	99.405	ENSCAFG00000016438	PRPF19	98	99.405	Canis_familiaris
ENSG00000110107	PRPF19	100	99.405	ENSCAFG00020012565	PRPF19	100	99.405	Canis_lupus_dingo
ENSG00000110107	PRPF19	100	100.000	ENSCHIG00000018281	PRPF19	100	99.802	Capra_hircus
ENSG00000110107	PRPF19	99	99.197	ENSTSYG00000006860	PRPF19	99	99.197	Carlito_syrichta
ENSG00000110107	PRPF19	100	100.000	ENSCAPG00000016225	PRPF19	100	98.998	Cavia_aperea
ENSG00000110107	PRPF19	100	100.000	ENSCPOG00000020688	PRPF19	100	99.405	Cavia_porcellus
ENSG00000110107	PRPF19	100	100.000	ENSCCAG00000025839	PRPF19	100	99.802	Cebus_capucinus
ENSG00000110107	PRPF19	100	100.000	ENSCATG00000041921	PRPF19	100	100.000	Cercocebus_atys
ENSG00000110107	PRPF19	100	100.000	ENSCLAG00000003338	PRPF19	100	99.396	Chinchilla_lanigera
ENSG00000110107	PRPF19	100	100.000	ENSCSAG00000006254	PRPF19	100	100.000	Chlorocebus_sabaeus
ENSG00000110107	PRPF19	100	100.000	ENSCHOG00000005840	PRPF19	100	88.103	Choloepus_hoffmanni
ENSG00000110107	PRPF19	100	97.619	ENSCPBG00000027061	PRPF19	100	97.619	Chrysemys_picta_bellii
ENSG00000110107	PRPF19	100	69.231	ENSCING00000016625	-	99	68.349	Ciona_intestinalis
ENSG00000110107	PRPF19	100	68.452	ENSCSAVG00000002027	-	99	68.452	Ciona_savignyi
ENSG00000110107	PRPF19	99	99.346	ENSCANG00000027155	PRPF19	99	46.257	Colobus_angolensis_palliatus
ENSG00000110107	PRPF19	100	100.000	ENSCGRG00001002699	Prpf19	100	99.405	Cricetulus_griseus_chok1gshd
ENSG00000110107	PRPF19	100	100.000	ENSCGRG00000008964	Prpf19	100	98.413	Cricetulus_griseus_crigri
ENSG00000110107	PRPF19	100	88.571	ENSCSEG00000010411	prpf19	100	84.950	Cynoglossus_semilaevis
ENSG00000110107	PRPF19	100	84.762	ENSCVAG00000012011	prpf19	100	84.752	Cyprinodon_variegatus
ENSG00000110107	PRPF19	100	88.571	ENSDARG00000015239	prpf19	100	85.347	Danio_rerio
ENSG00000110107	PRPF19	100	100.000	ENSDNOG00000005797	PRPF19	100	99.802	Dasypus_novemcinctus
ENSG00000110107	PRPF19	100	100.000	ENSDORG00000006906	Prpf19	100	99.405	Dipodomys_ordii
ENSG00000110107	PRPF19	100	70.909	FBgn0261119	Prp19	99	65.882	Drosophila_melanogaster
ENSG00000110107	PRPF19	100	99.038	ENSETEG00000012295	PRPF19	100	86.905	Echinops_telfairi
ENSG00000110107	PRPF19	100	86.538	ENSEBUG00000013075	prpf19	100	77.143	Eptatretus_burgeri
ENSG00000110107	PRPF19	100	100.000	ENSEASG00005008056	PRPF19	98	99.160	Equus_asinus_asinus
ENSG00000110107	PRPF19	100	100.000	ENSECAG00000007322	PRPF19	100	99.603	Equus_caballus
ENSG00000110107	PRPF19	100	84.762	ENSELUG00000020276	-	100	84.554	Esox_lucius
ENSG00000110107	PRPF19	100	86.538	ENSELUG00000004578	prpf19	100	78.571	Esox_lucius
ENSG00000110107	PRPF19	100	99.405	ENSFCAG00000013668	PRPF19	100	99.405	Felis_catus
ENSG00000110107	PRPF19	100	97.222	ENSFALG00000012084	PRPF19	100	97.222	Ficedula_albicollis
ENSG00000110107	PRPF19	100	100.000	ENSFDAG00000009420	PRPF19	96	99.052	Fukomys_damarensis
ENSG00000110107	PRPF19	100	87.619	ENSFHEG00000022135	prpf19	100	84.752	Fundulus_heteroclitus
ENSG00000110107	PRPF19	100	90.476	ENSGMOG00000014756	prpf19	100	86.337	Gadus_morhua
ENSG00000110107	PRPF19	100	97.619	ENSGALG00000036530	PRPF19	100	97.619	Gallus_gallus
ENSG00000110107	PRPF19	100	85.714	ENSGAFG00000008931	prpf19	100	84.158	Gambusia_affinis
ENSG00000110107	PRPF19	100	87.619	ENSGACG00000017976	prpf19	100	84.950	Gasterosteus_aculeatus
ENSG00000110107	PRPF19	100	97.817	ENSGAGG00000013328	PRPF19	100	97.817	Gopherus_agassizii
ENSG00000110107	PRPF19	100	100.000	ENSGGOG00000008648	PRPF19	100	100.000	Gorilla_gorilla
ENSG00000110107	PRPF19	100	88.571	ENSHBUG00000008394	prpf19	100	84.950	Haplochromis_burtoni
ENSG00000110107	PRPF19	100	99.038	ENSHGLG00000003934	PRPF19	100	99.008	Heterocephalus_glaber_female
ENSG00000110107	PRPF19	100	99.038	ENSHGLG00100010649	PRPF19	100	80.282	Heterocephalus_glaber_male
ENSG00000110107	PRPF19	100	87.619	ENSHCOG00000016720	prpf19	100	83.762	Hippocampus_comes
ENSG00000110107	PRPF19	100	88.571	ENSIPUG00000013084	prpf19	100	85.743	Ictalurus_punctatus
ENSG00000110107	PRPF19	100	99.405	ENSSTOG00000001598	PRPF19	100	99.405	Ictidomys_tridecemlineatus
ENSG00000110107	PRPF19	100	100.000	ENSJJAG00000020609	Prpf19	100	99.405	Jaculus_jaculus
ENSG00000110107	PRPF19	100	87.619	ENSKMAG00000010257	prpf19	100	85.149	Kryptolebias_marmoratus
ENSG00000110107	PRPF19	100	87.619	ENSLBEG00000027436	prpf19	100	85.347	Labrus_bergylta
ENSG00000110107	PRPF19	100	90.385	ENSLACG00000003434	PRPF19	100	90.079	Latimeria_chalumnae
ENSG00000110107	PRPF19	100	91.346	ENSLOCG00000008123	prpf19	100	74.200	Lepisosteus_oculatus
ENSG00000110107	PRPF19	100	99.038	ENSLAFG00000002644	PRPF19	100	96.353	Loxodonta_africana
ENSG00000110107	PRPF19	100	100.000	ENSMFAG00000036743	PRPF19	100	100.000	Macaca_fascicularis
ENSG00000110107	PRPF19	100	100.000	ENSMMUG00000014530	PRPF19	100	100.000	Macaca_mulatta
ENSG00000110107	PRPF19	100	100.000	ENSMNEG00000044485	PRPF19	100	100.000	Macaca_nemestrina
ENSG00000110107	PRPF19	100	100.000	ENSMLEG00000043312	PRPF19	100	100.000	Mandrillus_leucophaeus
ENSG00000110107	PRPF19	100	88.571	ENSMAMG00000006843	prpf19	100	85.347	Mastacembelus_armatus
ENSG00000110107	PRPF19	100	88.571	ENSMZEG00005013356	prpf19	100	84.950	Maylandia_zebra
ENSG00000110107	PRPF19	100	96.154	ENSMGAG00000003180	PRPF19	100	90.782	Meleagris_gallopavo
ENSG00000110107	PRPF19	100	100.000	ENSMAUG00000012585	Prpf19	100	98.611	Mesocricetus_auratus
ENSG00000110107	PRPF19	100	100.000	ENSMICG00000011236	PRPF19	100	100.000	Microcebus_murinus
ENSG00000110107	PRPF19	100	100.000	ENSMOCG00000010383	Prpf19	100	99.405	Microtus_ochrogaster
ENSG00000110107	PRPF19	100	86.538	ENSMMOG00000003138	prpf19	100	84.921	Mola_mola
ENSG00000110107	PRPF19	100	100.000	ENSMODG00000020338	PRPF19	100	99.603	Monodelphis_domestica
ENSG00000110107	PRPF19	100	86.538	ENSMALG00000010981	prpf19	99	76.803	Monopterus_albus
ENSG00000110107	PRPF19	100	100.000	MGP_CAROLIEiJ_G0022704	Prpf19	100	99.405	Mus_caroli
ENSG00000110107	PRPF19	100	100.000	ENSMUSG00000024735	Prpf19	100	99.405	Mus_musculus
ENSG00000110107	PRPF19	100	100.000	MGP_PahariEiJ_G0014198	Prpf19	100	99.405	Mus_pahari
ENSG00000110107	PRPF19	100	100.000	MGP_SPRETEiJ_G0023618	Prpf19	100	99.405	Mus_spretus
ENSG00000110107	PRPF19	100	99.405	ENSMPUG00000014432	PRPF19	100	99.405	Mustela_putorius_furo
ENSG00000110107	PRPF19	100	99.038	ENSMLUG00000017597	PRPF19	100	94.990	Myotis_lucifugus
ENSG00000110107	PRPF19	100	100.000	ENSNGAG00000012671	Prpf19	100	98.810	Nannospalax_galili
ENSG00000110107	PRPF19	100	88.571	ENSNBRG00000000055	prpf19	100	84.950	Neolamprologus_brichardi
ENSG00000110107	PRPF19	100	100.000	ENSNLEG00000013618	PRPF19	100	100.000	Nomascus_leucogenys
ENSG00000110107	PRPF19	100	100.000	ENSOPRG00000008630	PRPF19	100	95.775	Ochotona_princeps
ENSG00000110107	PRPF19	100	100.000	ENSODEG00000004043	PRPF19	100	98.810	Octodon_degus
ENSG00000110107	PRPF19	100	88.571	ENSONIG00000004880	prpf19	100	84.950	Oreochromis_niloticus
ENSG00000110107	PRPF19	100	100.000	ENSOCUG00000015689	PRPF19	100	96.000	Oryctolagus_cuniculus
ENSG00000110107	PRPF19	100	87.619	ENSORLG00000004666	prpf19	100	84.950	Oryzias_latipes
ENSG00000110107	PRPF19	100	87.619	ENSORLG00020013561	prpf19	100	84.950	Oryzias_latipes_hni
ENSG00000110107	PRPF19	100	87.619	ENSORLG00015022196	prpf19	100	84.950	Oryzias_latipes_hsok
ENSG00000110107	PRPF19	100	86.667	ENSOMEG00000004424	prpf19	100	84.158	Oryzias_melastigma
ENSG00000110107	PRPF19	100	100.000	ENSOGAG00000016756	PRPF19	100	99.802	Otolemur_garnettii
ENSG00000110107	PRPF19	100	100.000	ENSOARG00000015596	PRPF19	100	99.802	Ovis_aries
ENSG00000110107	PRPF19	99	97.446	ENSPPAG00000030246	PRPF19	100	97.446	Pan_paniscus
ENSG00000110107	PRPF19	100	99.405	ENSPPRG00000002470	PRPF19	100	99.405	Panthera_pardus
ENSG00000110107	PRPF19	100	99.038	ENSPTIG00000006541	PRPF19	99	99.396	Panthera_tigris_altaica
ENSG00000110107	PRPF19	100	100.000	ENSPTRG00000003724	PRPF19	100	100.000	Pan_troglodytes
ENSG00000110107	PRPF19	100	100.000	ENSPANG00000002762	PRPF19	100	100.000	Papio_anubis
ENSG00000110107	PRPF19	100	89.524	ENSPKIG00000019715	prpf19	100	84.950	Paramormyrops_kingsleyae
ENSG00000110107	PRPF19	100	97.115	ENSPSIG00000007497	PRPF19	100	97.375	Pelodiscus_sinensis
ENSG00000110107	PRPF19	100	87.500	ENSPMGG00000017527	prpf19	100	84.921	Periophthalmus_magnuspinnatus
ENSG00000110107	PRPF19	100	100.000	ENSPEMG00000019270	Prpf19	100	98.214	Peromyscus_maniculatus_bairdii
ENSG00000110107	PRPF19	100	100.000	ENSPCIG00000003485	PRPF19	79	99.143	Phascolarctos_cinereus
ENSG00000110107	PRPF19	100	85.714	ENSPFOG00000002558	prpf19	100	84.158	Poecilia_formosa
ENSG00000110107	PRPF19	100	85.714	ENSPLAG00000017942	prpf19	100	84.158	Poecilia_latipinna
ENSG00000110107	PRPF19	100	85.714	ENSPMEG00000008638	prpf19	100	84.158	Poecilia_mexicana
ENSG00000110107	PRPF19	100	86.667	ENSPREG00000002489	prpf19	96	86.364	Poecilia_reticulata
ENSG00000110107	PRPF19	100	100.000	ENSPPYG00000003202	PRPF19	92	98.351	Pongo_abelii
ENSG00000110107	PRPF19	100	99.405	ENSPCAG00000001930	PRPF19	100	99.405	Procavia_capensis
ENSG00000110107	PRPF19	100	100.000	ENSPCOG00000014017	PRPF19	100	100.000	Propithecus_coquereli
ENSG00000110107	PRPF19	100	100.000	ENSPVAG00000014669	PRPF19	100	99.603	Pteropus_vampyrus
ENSG00000110107	PRPF19	100	88.571	ENSPNYG00000000859	prpf19	100	84.950	Pundamilia_nyererei
ENSG00000110107	PRPF19	100	90.476	ENSPNAG00000019245	prpf19	100	86.139	Pygocentrus_nattereri
ENSG00000110107	PRPF19	100	100.000	ENSRNOG00000020897	Prpf19	100	99.405	Rattus_norvegicus
ENSG00000110107	PRPF19	100	100.000	ENSRBIG00000036672	PRPF19	100	100.000	Rhinopithecus_bieti
ENSG00000110107	PRPF19	100	100.000	ENSRROG00000041572	PRPF19	100	100.000	Rhinopithecus_roxellana
ENSG00000110107	PRPF19	100	100.000	ENSSBOG00000022840	PRPF19	100	99.802	Saimiri_boliviensis_boliviensis
ENSG00000110107	PRPF19	100	100.000	ENSSHAG00000009462	PRPF19	100	99.603	Sarcophilus_harrisii
ENSG00000110107	PRPF19	100	87.500	ENSSFOG00015001236	prpf19	100	83.135	Scleropages_formosus
ENSG00000110107	PRPF19	100	88.571	ENSSMAG00000002273	prpf19	100	85.743	Scophthalmus_maximus
ENSG00000110107	PRPF19	100	88.571	ENSSDUG00000003299	prpf19	100	85.545	Seriola_dumerili
ENSG00000110107	PRPF19	100	88.571	ENSSLDG00000003019	prpf19	100	85.545	Seriola_lalandi_dorsalis
ENSG00000110107	PRPF19	100	97.024	ENSSPUG00000019328	PRPF19	100	97.024	Sphenodon_punctatus
ENSG00000110107	PRPF19	100	88.571	ENSSPAG00000008546	prpf19	100	85.743	Stegastes_partitus
ENSG00000110107	PRPF19	100	100.000	ENSSSCG00000013107	PRPF19	100	99.603	Sus_scrofa
ENSG00000110107	PRPF19	100	97.619	ENSTGUG00000006319	PRPF19	100	97.619	Taeniopygia_guttata
ENSG00000110107	PRPF19	100	87.619	ENSTRUG00000008502	prpf19	100	84.356	Takifugu_rubripes
ENSG00000110107	PRPF19	100	67.921	ENSTNIG00000014219	prpf19	100	67.921	Tetraodon_nigroviridis
ENSG00000110107	PRPF19	100	99.405	ENSTTRG00000012476	PRPF19	100	99.405	Tursiops_truncatus
ENSG00000110107	PRPF19	100	99.405	ENSUAMG00000011280	PRPF19	100	99.405	Ursus_americanus
ENSG00000110107	PRPF19	100	99.038	ENSUMAG00000011609	PRPF19	83	99.052	Ursus_maritimus
ENSG00000110107	PRPF19	100	99.038	ENSVPAG00000010516	PRPF19	100	99.119	Vicugna_pacos
ENSG00000110107	PRPF19	100	99.405	ENSVVUG00000005291	PRPF19	100	99.405	Vulpes_vulpes
ENSG00000110107	PRPF19	100	85.421	ENSXETG00000011938	prpf19	100	85.421	Xenopus_tropicalis
ENSG00000110107	PRPF19	100	86.667	ENSXCOG00000003141	prpf19	100	84.158	Xiphophorus_couchianus
ENSG00000110107	PRPF19	100	86.667	ENSXMAG00000008485	prpf19	100	84.356	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000209	protein polyubiquitination	11435423.	IDA	Process
GO:0000244	spliceosomal tri-snRNP complex assembly	20595234.	IDA	Process
GO:0000245	spliceosomal complex assembly	16332694.	IMP	Process
GO:0000349	generation of catalytic spliceosome for first transesterification step	21873635.	IBA	Process
GO:0000398	mRNA splicing, via spliceosome	11991638.	IC	Process
GO:0000398	mRNA splicing, via spliceosome	20176811.	IDA	Process
GO:0000398	mRNA splicing, via spliceosome	-	TAS	Process
GO:0000974	Prp19 complex	21873635.	IBA	Component
GO:0000974	Prp19 complex	20176811.	IDA	Component
GO:0001833	inner cell mass cell proliferation	-	IEA	Process
GO:0004842	ubiquitin-protein transferase activity	21873635.	IBA	Function
GO:0005515	protein binding	19188445.19633697.19641227.20176811.20467437.20595234.21536736.22365833.22569250.22961380.	IPI	Function
GO:0005634	nucleus	11435423.19188445.	IDA	Component
GO:0005654	nucleoplasm	-	TAS	Component
GO:0005662	DNA replication factor A complex	24332808.	IDA	Component
GO:0005737	cytoplasm	11435423.	IDA	Component
GO:0005811	lipid droplet	-	IEA	Component
GO:0005819	spindle	-	IEA	Component
GO:0006283	transcription-coupled nucleotide-excision repair	-	TAS	Process
GO:0006303	double-strand break repair via nonhomologous end joining	18263876.	IMP	Process
GO:0008610	lipid biosynthetic process	-	IEA	Process
GO:0010498	proteasomal protein catabolic process	17349974.	IMP	Process
GO:0016020	membrane	19946888.	HDA	Component
GO:0016607	nuclear speck	16332694.24332808.	IDA	Component
GO:0034450	ubiquitin-ubiquitin ligase activity	11435423.	IDA	Function
GO:0034613	cellular protein localization	18263876.	IMP	Process
GO:0035861	site of double-strand break	18263876.	IDA	Component
GO:0042802	identical protein binding	16332694.	IPI	Function
GO:0045666	positive regulation of neuron differentiation	-	IEA	Process
GO:0048026	positive regulation of mRNA splicing, via spliceosome	-	IEA	Process
GO:0048711	positive regulation of astrocyte differentiation	-	IEA	Process
GO:0061630	ubiquitin protein ligase activity	11435423.	IDA	Function
GO:0061630	ubiquitin protein ligase activity	20595234.	IMP	Function
GO:0070534	protein K63-linked ubiquitination	20595234.24332808.	IMP	Process
GO:0071006	U2-type catalytic step 1 spliceosome	21873635.	IBA	Component
GO:0071007	U2-type catalytic step 2 spliceosome	28076346.	IDA	Component
GO:0071013	catalytic step 2 spliceosome	21873635.	IBA	Component
GO:0071013	catalytic step 2 spliceosome	11991638.	IDA	Component
GO:0072422	signal transduction involved in DNA damage checkpoint	24332808.	IMP	Process