EuRBPDB

Description

Ensembl ID: ENSG00000110172 (Gene tree)
Gene ID: 26973
Gene Symbol: CHORDC1
Alias: CHP1|CHP-1
Full Name: cysteine and histidine rich domain containing 1
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Minus strand
Length: 29,418 bases
Position: chr11:90,193,947-90,223,364
Accession: 14525
RBP type: non-canonical RBP
Summary: (Cysteine And Histidine Rich Domain Containing 1) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include Hsp90 protein binding. An important paralog of this gene is ITGB1BP2.

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000529726	CHORDC1-205	4805	-	ENSP00000436632	144 (aa)	-	E9PHZ2
ENST00000533724	CHORDC1-209	5361	-	-	- (aa)	-	-
ENST00000533062	CHORDC1-208	575	-	ENSP00000433440	39 (aa)	-	E9PL00
ENST00000533739	CHORDC1-210	582	-	-	- (aa)	-	-
ENST00000525317	CHORDC1-203	1136	-	ENSP00000436945	184 (aa)	-	E9PPQ5
ENST00000457199	CHORDC1-202	2003	XM_017017540	ENSP00000401080	313 (aa)	XP_016873029	Q9UHD1
ENST00000530765	CHORDC1-207	564	-	ENSP00000431929	116 (aa)	-	E9PIZ4
ENST00000529402	CHORDC1-204	809	-	ENSP00000432019	117 (aa)	-	E9PIF7
ENST00000320585	CHORDC1-201	2654	-	ENSP00000319255	332 (aa)	-	Q9UHD1
ENST00000533772	CHORDC1-211	566	-	ENSP00000434040	120 (aa)	-	E9PSD5
ENST00000529987	CHORDC1-206	1698	-	ENSP00000433719	144 (aa)	-	E9PHZ2

Gene Model

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000110172	Stroke	1.6616655E-004	19369658

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000110172	rs34787918	11	90218200	G	Basophil percentage of white cells	27863252	[0.015-0.029] unit decrease	0.0223271	EFO_0007992

Protein-Protein Interaction (PPI)

* RBP PPI network refers to all genes directly bind to RBP

Orthologs identified by RBPome

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000110172	CHORDC1	100	96.196	ENSMUSG00000001774	Chordc1	100	96.196	Mus_musculus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0005515	protein binding	19875381.20230755.23414517.25036637.26496610.	IPI	Function
GO:0005524	ATP binding	-	IEA	Function
GO:0005575	cellular_component	-	ND	Component
GO:0008270	zinc ion binding	-	IEA	Function
GO:0010824	regulation of centrosome duplication	-	IEA	Process
GO:0043531	ADP binding	-	IEA	Function
GO:0051879	Hsp90 protein binding	19875381.	IPI	Function
GO:0061077	chaperone-mediated protein folding	-	ISS	Process
GO:1900034	regulation of cellular response to heat	-	ISS	Process
GO:2000299	negative regulation of Rho-dependent protein serine/threonine kinase activity	-	IEA	Process