EuRBPDB

Description

RBDs

RBPome

PRI

Literatures

Expression

Transcripts

Gene Model

Pathways

Phenotypes

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000110321 (Gene tree)
Gene ID: 1982
Gene Symbol: EIF4G2
Alias: DAP5|NAT1|p97
Full Name: eukaryotic translation initiation factor 4 gamma 2
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Minus strand
Length: 12,065 bases
Position: chr11:10,797,046-10,809,110
Accession: 3297
RBP type: canonical RBP
Summary: Translation initiation is mediated by specific recognition of the cap structure by eukaryotic translation initiation factor 4F (eIF4F), which is a cap binding protein complex that consists of three subunits: eIF4A, eIF4E and eIF4G. The protein encoded by this gene shares similarity with the C-terminal region of eIF4G that contains the binding sites for eIF4A and eIF3; eIF4G, in addition, contains a binding site for eIF4E at the N-terminus. Unlike eIF4G, which supports cap-dependent and independent translation, this gene product functions as a general repressor of translation by forming translationally inactive complexes. In vitro and in vivo studies indicate that translation of this mRNA initiates exclusively at a non-AUG (GUG) codon. Alternatively spliced transcript variants encoding different isoforms of this gene have been described. [provided by RefSeq, Jul 2008]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000433561	MA3	PF02847.17	4.6e-18	1	1
ENSP00000379778	MA3	PF02847.17	2.7e-16	1	1
ENSP00000340281	MA3	PF02847.17	2.8e-16	1	1
ENSP00000433371	MA3	PF02847.17	2.8e-16	1	1
ENSP00000433664	MA3	PF02847.17	2.8e-16	1	1
ENSP00000492820	MA3	PF02847.17	2.8e-16	1	1
ENSP00000434815	MA3	PF02847.17	7.1e-07	1	1
ENSP00000431583	MIF4G	PF02854.19	7.5e-58	1	1
ENSP00000379778	MIF4G	PF02854.19	4e-57	1	1
ENSP00000340281	MIF4G	PF02854.19	4.3e-57	1	1
ENSP00000433371	MIF4G	PF02854.19	4.3e-57	1	1
ENSP00000433664	MIF4G	PF02854.19	4.3e-57	1	1
ENSP00000492820	MIF4G	PF02854.19	4.3e-57	1	1
ENSP00000433121	MIF4G	PF02854.19	2.3e-49	1	1
ENSP00000435523	MIF4G	PF02854.19	9.5e-37	1	1
ENSP00000434940	MIF4G	PF02854.19	7.3e-18	1	1
ENSP00000431511	MIF4G	PF02854.19	4.7e-10	1	1
ENSP00000379778	W2	PF02020.18	7.5e-20	1	1
ENSP00000492820	W2	PF02020.18	8e-20	1	1
ENSP00000340281	W2	PF02020.18	8e-20	1	1
ENSP00000433371	W2	PF02020.18	8e-20	1	1
ENSP00000433664	W2	PF02020.18	8e-20	1	1
ENSP00000434815	W2	PF02020.18	8e-11	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
22681889	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts	4SURIC & HEK293	2012 May	Baltz AG	DOI: 10.1016/j.molcel.2012.05.021
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
29431736	Capturing the interactome of newly transcribed RNA	PolyT-RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	RIC & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
22658674	Insights into RNA biology from an atlas of mammalian mRNA-binding proteins	RIC & Hela	2012 May 31	Castello A	DOI: 10.1016/j.cell.2012.04.031
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
27453046	Comprehensive Identification of RNA-Binding Domains in Human Cells	RIC & Hela	2016 Aug 18	Castello A	DOI: 10.1016/j.molcel.2016.06.029
30352994	Discovery of RNA-binding proteins and characterization of their dynamic responses by enhanced RNA interactome capture	RIC & Jurkat	2018 Oct 23	Perez-Perri JI	DOI:10.1038/s41467-018-06557-8

Protein-RNA interaction（RNA-Binding Site）

Click here to download all RNA binding sites

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
31010886	eIF4G2 balances its own mRNA translation via a PCBP2-based feedback loop.	RNA	2019 Jul	Smirnova VV	doi: 10.1261/rna.065623.118

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000525681	EIF4G2-205	3654	-	ENSP00000433371	907 (aa)	-	D3DQV9
ENST00000531416	EIF4G2-218	1969	-	ENSP00000431583	444 (aa)	-	H0YCH5
ENST00000339995	EIF4G2-201	3978	-	ENSP00000340281	907 (aa)	-	D3DQV9
ENST00000396525	EIF4G2-202	3346	-	ENSP00000379778	869 (aa)	-	H0Y3P2
ENST00000530702	EIF4G2-216	563	-	ENSP00000435912	84 (aa)	-	H0YEI7
ENST00000525995	EIF4G2-207	592	-	-	- (aa)	-	-
ENST00000534246	EIF4G2-228	523	-	-	- (aa)	-	-
ENST00000526148	EIF4G2-208	4001	-	ENSP00000433664	907 (aa)	-	D3DQV9
ENST00000528839	EIF4G2-213	702	-	ENSP00000434815	234 (aa)	-	H0YE22
ENST00000525972	EIF4G2-206	584	-	-	- (aa)	-	-
ENST00000534470	EIF4G2-230	520	-	-	- (aa)	-	-
ENST00000528562	EIF4G2-212	601	-	ENSP00000435220	46 (aa)	-	H0YE87
ENST00000527526	EIF4G2-211	555	-	ENSP00000436235	112 (aa)	-	H0YEN8
ENST00000640650	EIF4G2-232	2724	-	ENSP00000492820	907 (aa)	-	P78344
ENST00000527015	EIF4G2-209	582	-	-	- (aa)	-	-
ENST00000532349	EIF4G2-224	550	-	-	- (aa)	-	-
ENST00000532570	EIF4G2-226	573	-	ENSP00000431511	129 (aa)	-	H0YCF8
ENST00000530564	EIF4G2-215	849	-	-	- (aa)	-	-
ENST00000530211	EIF4G2-214	591	-	ENSP00000433335	116 (aa)	-	H0YDC0
ENST00000532383	EIF4G2-225	6769	-	-	- (aa)	-	-
ENST00000532152	EIF4G2-223	587	-	-	- (aa)	-	-
ENST00000531507	EIF4G2-219	591	-	-	- (aa)	-	-
ENST00000533485	EIF4G2-227	806	-	-	- (aa)	-	-
ENST00000524932	EIF4G2-203	1286	-	ENSP00000435523	244 (aa)	-	H0YEC5
ENST00000534272	EIF4G2-229	591	-	-	- (aa)	-	-
ENST00000534605	EIF4G2-231	198	-	ENSP00000436680	20 (aa)	-	H0YEW3
ENST00000525606	EIF4G2-204	690	-	-	- (aa)	-	-
ENST00000532082	EIF4G2-221	1069	-	ENSP00000433121	282 (aa)	-	H0YD77
ENST00000531180	EIF4G2-217	557	-	ENSP00000433561	185 (aa)	-	E9PKF8
ENST00000531647	EIF4G2-220	579	-	ENSP00000433217	84 (aa)	-	H0YD99
ENST00000532120	EIF4G2-222	223	-	-	- (aa)	-	-
ENST00000527419	EIF4G2-210	571	-	ENSP00000434940	88 (aa)	-	H0YE44

Gene Model

Click here to download ENSG00000110321's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa03013	RNA transport	KEGG
hsa05416	Viral myocarditis	KEGG

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000110321	Blood Vessels	1.296e-005	-

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000110321's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000110321	EIF4G2	99	88.506	ENSAPOG00000016586	eif4g2b	96	85.492	Acanthochromis_polyacanthus
ENSG00000110321	EIF4G2	97	84.706	ENSAPOG00000014976	eif4g2a	97	75.145	Acanthochromis_polyacanthus
ENSG00000110321	EIF4G2	100	100.000	ENSAMEG00000014576	EIF4G2	95	99.779	Ailuropoda_melanoleuca
ENSG00000110321	EIF4G2	97	83.529	ENSACIG00000000178	eif4g2a	97	73.410	Amphilophus_citrinellus
ENSG00000110321	EIF4G2	99	87.356	ENSACIG00000007752	eif4g2b	96	85.132	Amphilophus_citrinellus
ENSG00000110321	EIF4G2	82	86.111	ENSAOCG00000002148	eif4g2a	96	75.430	Amphiprion_ocellaris
ENSG00000110321	EIF4G2	99	88.506	ENSAOCG00000013778	eif4g2b	96	85.492	Amphiprion_ocellaris
ENSG00000110321	EIF4G2	99	88.506	ENSAPEG00000014252	eif4g2b	96	85.372	Amphiprion_percula
ENSG00000110321	EIF4G2	100	63.251	ENSAPEG00000010403	eif4g2a	97	75.366	Amphiprion_percula
ENSG00000110321	EIF4G2	99	88.506	ENSATEG00000002419	eif4g2b	98	85.366	Anabas_testudineus
ENSG00000110321	EIF4G2	97	82.353	ENSATEG00000006003	eif4g2a	98	77.163	Anabas_testudineus
ENSG00000110321	EIF4G2	99	94.855	ENSAPLG00000005642	EIF4G2	95	94.855	Anas_platyrhynchos
ENSG00000110321	EIF4G2	100	93.033	ENSACAG00000008398	EIF4G2	95	93.289	Anolis_carolinensis
ENSG00000110321	EIF4G2	100	100.000	ENSANAG00000036301	-	100	99.779	Aotus_nancymaae
ENSG00000110321	EIF4G2	99	89.062	ENSANAG00000021255	-	100	86.766	Aotus_nancymaae
ENSG00000110321	EIF4G2	97	83.529	ENSACLG00000000429	eif4g2a	95	72.976	Astatotilapia_calliptera
ENSG00000110321	EIF4G2	99	86.207	ENSACLG00000021001	eif4g2b	95	84.951	Astatotilapia_calliptera
ENSG00000110321	EIF4G2	90	92.405	ENSAMXG00000003883	eif4g2b	96	83.673	Astyanax_mexicanus
ENSG00000110321	EIF4G2	99	88.506	ENSAMXG00000010137	eif4g2a	95	83.293	Astyanax_mexicanus
ENSG00000110321	EIF4G2	100	100.000	ENSBTAG00000020308	EIF4G2	100	100.000	Bos_taurus
ENSG00000110321	EIF4G2	100	100.000	ENSCJAG00000010633	EIF4G2	100	99.890	Callithrix_jacchus
ENSG00000110321	EIF4G2	100	100.000	ENSCAFG00000007666	EIF4G2	97	99.890	Canis_familiaris
ENSG00000110321	EIF4G2	100	100.000	ENSCAFG00020015650	EIF4G2	100	99.857	Canis_lupus_dingo
ENSG00000110321	EIF4G2	99	99.888	ENSCHIG00000017894	EIF4G2	99	99.888	Capra_hircus
ENSG00000110321	EIF4G2	99	95.402	ENSTSYG00000028832	-	97	85.749	Carlito_syrichta
ENSG00000110321	EIF4G2	100	100.000	ENSTSYG00000000600	-	100	99.765	Carlito_syrichta
ENSG00000110321	EIF4G2	83	100.000	ENSCAPG00000012057	EIF4G2	95	85.294	Cavia_aperea
ENSG00000110321	EIF4G2	100	100.000	ENSCPOG00000009036	EIF4G2	100	99.885	Cavia_porcellus
ENSG00000110321	EIF4G2	100	100.000	ENSCCAG00000020617	EIF4G2	99	98.585	Cebus_capucinus
ENSG00000110321	EIF4G2	100	100.000	ENSCATG00000040907	EIF4G2	100	99.885	Cercocebus_atys
ENSG00000110321	EIF4G2	100	100.000	ENSCLAG00000016511	EIF4G2	100	99.655	Chinchilla_lanigera
ENSG00000110321	EIF4G2	100	100.000	ENSCSAG00000004613	EIF4G2	93	99.890	Chlorocebus_sabaeus
ENSG00000110321	EIF4G2	99	97.701	ENSCHOG00000011414	EIF4G2	86	87.436	Choloepus_hoffmanni
ENSG00000110321	EIF4G2	100	93.443	ENSCPBG00000005181	EIF4G2	97	90.705	Chrysemys_picta_bellii
ENSG00000110321	EIF4G2	83	65.753	ENSCING00000008855	-	73	45.368	Ciona_intestinalis
ENSG00000110321	EIF4G2	93	60.714	ENSCSAVG00000007466	-	99	41.417	Ciona_savignyi
ENSG00000110321	EIF4G2	100	100.000	ENSCANG00000038118	EIF4G2	100	99.770	Colobus_angolensis_palliatus
ENSG00000110321	EIF4G2	100	100.000	ENSCGRG00001000464	Eif4g2	100	99.008	Cricetulus_griseus_chok1gshd
ENSG00000110321	EIF4G2	100	100.000	ENSCGRG00000010654	Eif4g2	100	99.008	Cricetulus_griseus_crigri
ENSG00000110321	EIF4G2	100	88.115	ENSCSEG00000021334	eif4g2b	98	85.389	Cynoglossus_semilaevis
ENSG00000110321	EIF4G2	99	79.004	ENSCSEG00000019490	eif4g2a	98	74.142	Cynoglossus_semilaevis
ENSG00000110321	EIF4G2	99	88.506	ENSCVAG00000008364	eif4g2b	96	84.892	Cyprinodon_variegatus
ENSG00000110321	EIF4G2	93	85.366	ENSCVAG00000018612	eif4g2a	96	74.670	Cyprinodon_variegatus
ENSG00000110321	EIF4G2	99	88.506	ENSDARG00000020377	eif4g2a	99	81.920	Danio_rerio
ENSG00000110321	EIF4G2	99	87.356	ENSDARG00000057167	eif4g2b	99	82.739	Danio_rerio
ENSG00000110321	EIF4G2	100	87.143	ENSDNOG00000002222	EIF4G2	100	99.715	Dasypus_novemcinctus
ENSG00000110321	EIF4G2	100	100.000	ENSDORG00000014967	Eif4g2	100	99.669	Dipodomys_ordii
ENSG00000110321	EIF4G2	86	69.737	FBgn0010488	NAT1	82	42.470	Drosophila_melanogaster
ENSG00000110321	EIF4G2	99	97.701	ENSETEG00000018088	EIF4G2	92	99.242	Echinops_telfairi
ENSG00000110321	EIF4G2	94	48.821	ENSEBUG00000012926	eif4g2a	93	60.219	Eptatretus_burgeri
ENSG00000110321	EIF4G2	99	99.776	ENSEASG00005005881	EIF4G2	99	99.776	Equus_asinus_asinus
ENSG00000110321	EIF4G2	100	99.462	ENSECAG00000014700	EIF4G2	99	99.776	Equus_caballus
ENSG00000110321	EIF4G2	91	100.000	ENSEEUG00000000375	EIF4G2	100	99.753	Erinaceus_europaeus
ENSG00000110321	EIF4G2	99	86.207	ENSELUG00000011497	eif4g2b	96	82.562	Esox_lucius
ENSG00000110321	EIF4G2	99	88.506	ENSELUG00000015787	eif4g2a	95	83.914	Esox_lucius
ENSG00000110321	EIF4G2	100	100.000	ENSFCAG00000022269	EIF4G2	100	99.890	Felis_catus
ENSG00000110321	EIF4G2	99	94.253	ENSFALG00000001022	EIF4G2	97	94.246	Ficedula_albicollis
ENSG00000110321	EIF4G2	100	100.000	ENSFDAG00000000106	EIF4G2	100	99.559	Fukomys_damarensis
ENSG00000110321	EIF4G2	94	87.952	ENSFHEG00000006981	eif4g2a	99	71.061	Fundulus_heteroclitus
ENSG00000110321	EIF4G2	99	88.506	ENSFHEG00000010488	eif4g2b	98	84.994	Fundulus_heteroclitus
ENSG00000110321	EIF4G2	99	94.276	ENSGALG00000005587	EIF4G2	99	94.183	Gallus_gallus
ENSG00000110321	EIF4G2	94	86.747	ENSGAFG00000017112	eif4g2a	98	72.293	Gambusia_affinis
ENSG00000110321	EIF4G2	100	88.115	ENSGAFG00000007084	eif4g2b	95	82.163	Gambusia_affinis
ENSG00000110321	EIF4G2	99	85.053	ENSGACG00000009454	eif4g2b	99	81.362	Gasterosteus_aculeatus
ENSG00000110321	EIF4G2	97	64.621	ENSGACG00000015701	eif4g2a	98	73.806	Gasterosteus_aculeatus
ENSG00000110321	EIF4G2	100	93.468	ENSGAGG00000000987	EIF4G2	98	94.276	Gopherus_agassizii
ENSG00000110321	EIF4G2	100	100.000	ENSGGOG00000012972	EIF4G2	100	100.000	Gorilla_gorilla
ENSG00000110321	EIF4G2	99	86.207	ENSHBUG00000004770	eif4g2b	98	85.149	Haplochromis_burtoni
ENSG00000110321	EIF4G2	97	83.529	ENSHBUG00000018065	eif4g2a	98	73.804	Haplochromis_burtoni
ENSG00000110321	EIF4G2	100	100.000	ENSHGLG00000007052	-	100	99.655	Heterocephalus_glaber_female
ENSG00000110321	EIF4G2	97	88.482	ENSHGLG00000010266	-	98	73.043	Heterocephalus_glaber_female
ENSG00000110321	EIF4G2	89	92.121	ENSHGLG00000000461	-	98	75.687	Heterocephalus_glaber_female
ENSG00000110321	EIF4G2	100	100.000	ENSHGLG00100008407	-	100	99.669	Heterocephalus_glaber_male
ENSG00000110321	EIF4G2	100	87.069	ENSHGLG00100001472	-	98	77.035	Heterocephalus_glaber_male
ENSG00000110321	EIF4G2	97	88.482	ENSHGLG00100016127	-	96	93.137	Heterocephalus_glaber_male
ENSG00000110321	EIF4G2	98	81.707	ENSHGLG00100014723	-	99	79.375	Heterocephalus_glaber_male
ENSG00000110321	EIF4G2	92	88.889	ENSHCOG00000002542	eif4g2a	96	72.998	Hippocampus_comes
ENSG00000110321	EIF4G2	99	87.356	ENSHCOG00000016406	eif4g2b	96	82.874	Hippocampus_comes
ENSG00000110321	EIF4G2	95	88.095	ENSIPUG00000018469	eif4g2b	95	77.911	Ictalurus_punctatus
ENSG00000110321	EIF4G2	99	83.908	ENSIPUG00000010253	eif4g2a	98	81.655	Ictalurus_punctatus
ENSG00000110321	EIF4G2	99	99.664	ENSSTOG00000013612	EIF4G2	98	99.664	Ictidomys_tridecemlineatus
ENSG00000110321	EIF4G2	100	100.000	ENSJJAG00000021142	-	100	99.449	Jaculus_jaculus
ENSG00000110321	EIF4G2	100	86.190	ENSJJAG00000022275	-	100	94.601	Jaculus_jaculus
ENSG00000110321	EIF4G2	99	88.506	ENSKMAG00000006260	eif4g2b	96	85.114	Kryptolebias_marmoratus
ENSG00000110321	EIF4G2	88	89.610	ENSKMAG00000005641	eif4g2a	98	73.117	Kryptolebias_marmoratus
ENSG00000110321	EIF4G2	99	88.506	ENSLBEG00000002302	eif4g2b	96	81.609	Labrus_bergylta
ENSG00000110321	EIF4G2	97	82.353	ENSLBEG00000026992	eif4g2a	98	74.880	Labrus_bergylta
ENSG00000110321	EIF4G2	99	89.655	ENSLACG00000018374	EIF4G2	98	89.115	Latimeria_chalumnae
ENSG00000110321	EIF4G2	99	89.655	ENSLOCG00000003911	eif4g2a	95	87.179	Lepisosteus_oculatus
ENSG00000110321	EIF4G2	100	99.669	ENSLAFG00000012814	EIF4G2	100	99.669	Loxodonta_africana
ENSG00000110321	EIF4G2	100	100.000	ENSMFAG00000036500	EIF4G2	100	99.890	Macaca_fascicularis
ENSG00000110321	EIF4G2	100	100.000	ENSMMUG00000011436	EIF4G2	100	99.885	Macaca_mulatta
ENSG00000110321	EIF4G2	100	100.000	ENSMNEG00000038132	EIF4G2	100	99.885	Macaca_nemestrina
ENSG00000110321	EIF4G2	100	100.000	ENSMLEG00000037531	EIF4G2	100	99.885	Mandrillus_leucophaeus
ENSG00000110321	EIF4G2	100	88.115	ENSMAMG00000022916	eif4g2b	94	85.372	Mastacembelus_armatus
ENSG00000110321	EIF4G2	97	84.706	ENSMAMG00000021721	eif4g2a	98	75.058	Mastacembelus_armatus
ENSG00000110321	EIF4G2	97	83.529	ENSMZEG00005014732	eif4g2a	91	73.103	Maylandia_zebra
ENSG00000110321	EIF4G2	99	86.207	ENSMZEG00005013091	eif4g2b	95	84.951	Maylandia_zebra
ENSG00000110321	EIF4G2	99	94.253	ENSMGAG00000005834	EIF4G2	99	94.072	Meleagris_gallopavo
ENSG00000110321	EIF4G2	100	100.000	ENSMAUG00000012197	Eif4g2	100	99.228	Mesocricetus_auratus
ENSG00000110321	EIF4G2	100	100.000	ENSMICG00000017460	EIF4G2	100	99.885	Microcebus_murinus
ENSG00000110321	EIF4G2	100	100.000	ENSMOCG00000020486	Eif4g2	100	99.008	Microtus_ochrogaster
ENSG00000110321	EIF4G2	99	87.356	ENSMMOG00000009007	eif4g2b	96	80.120	Mola_mola
ENSG00000110321	EIF4G2	93	79.268	ENSMMOG00000017008	eif4g2a	98	74.310	Mola_mola
ENSG00000110321	EIF4G2	100	85.238	ENSMODG00000008364	EIF4G2	100	98.288	Monodelphis_domestica
ENSG00000110321	EIF4G2	99	88.506	ENSMALG00000012881	eif4g2b	96	83.914	Monopterus_albus
ENSG00000110321	EIF4G2	97	84.706	ENSMALG00000020494	eif4g2a	99	74.427	Monopterus_albus
ENSG00000110321	EIF4G2	100	100.000	ENSMUSG00000005610	Eif4g2	100	100.000	Mus_musculus
ENSG00000110321	EIF4G2	100	100.000	MGP_PahariEiJ_G0013542	Eif4g2	100	100.000	Mus_pahari
ENSG00000110321	EIF4G2	100	100.000	MGP_SPRETEiJ_G0031445	Eif4g2	100	100.000	Mus_spretus
ENSG00000110321	EIF4G2	100	100.000	ENSMPUG00000012886	EIF4G2	93	100.000	Mustela_putorius_furo
ENSG00000110321	EIF4G2	100	100.000	ENSMLUG00000016149	EIF4G2	97	99.779	Myotis_lucifugus
ENSG00000110321	EIF4G2	100	100.000	ENSNGAG00000024067	Eif4g2	100	99.118	Nannospalax_galili
ENSG00000110321	EIF4G2	99	86.207	ENSNBRG00000014520	eif4g2b	95	84.951	Neolamprologus_brichardi
ENSG00000110321	EIF4G2	97	83.529	ENSNBRG00000011756	eif4g2a	98	75.211	Neolamprologus_brichardi
ENSG00000110321	EIF4G2	100	100.000	ENSNLEG00000017628	EIF4G2	100	100.000	Nomascus_leucogenys
ENSG00000110321	EIF4G2	82	100.000	ENSMEUG00000004185	EIF4G2	73	100.000	Notamacropus_eugenii
ENSG00000110321	EIF4G2	100	100.000	ENSOPRG00000006302	-	100	94.512	Ochotona_princeps
ENSG00000110321	EIF4G2	99	81.609	ENSODEG00000001749	-	98	68.805	Octodon_degus
ENSG00000110321	EIF4G2	100	81.897	ENSODEG00000007261	-	93	80.992	Octodon_degus
ENSG00000110321	EIF4G2	100	77.305	ENSODEG00000013796	-	98	77.855	Octodon_degus
ENSG00000110321	EIF4G2	100	100.000	ENSODEG00000008998	-	100	98.137	Octodon_degus
ENSG00000110321	EIF4G2	97	84.706	ENSONIG00000006008	eif4g2a	95	74.833	Oreochromis_niloticus
ENSG00000110321	EIF4G2	100	87.295	ENSONIG00000003851	eif4g2b	96	84.281	Oreochromis_niloticus
ENSG00000110321	EIF4G2	100	100.000	ENSOANG00000015252	EIF4G2	96	96.082	Ornithorhynchus_anatinus
ENSG00000110321	EIF4G2	100	85.714	ENSOANG00000000254	-	98	97.712	Ornithorhynchus_anatinus
ENSG00000110321	EIF4G2	100	100.000	ENSOCUG00000013326	EIF4G2	96	99.560	Oryctolagus_cuniculus
ENSG00000110321	EIF4G2	99	89.655	ENSORLG00000018274	eif4g2b	97	83.527	Oryzias_latipes
ENSG00000110321	EIF4G2	95	84.524	ENSORLG00000007305	eif4g2a	98	75.150	Oryzias_latipes
ENSG00000110321	EIF4G2	95	84.524	ENSORLG00020010776	eif4g2a	99	69.194	Oryzias_latipes_hni
ENSG00000110321	EIF4G2	100	68.095	ENSORLG00020008223	eif4g2b	98	82.609	Oryzias_latipes_hni
ENSG00000110321	EIF4G2	98	58.065	ENSORLG00015008877	eif4g2a	98	71.429	Oryzias_latipes_hsok
ENSG00000110321	EIF4G2	99	89.655	ENSORLG00015002298	eif4g2b	95	83.835	Oryzias_latipes_hsok
ENSG00000110321	EIF4G2	100	62.544	ENSOMEG00000001540	eif4g2a	97	69.169	Oryzias_melastigma
ENSG00000110321	EIF4G2	99	86.207	ENSOMEG00000022918	-	94	80.846	Oryzias_melastigma
ENSG00000110321	EIF4G2	100	100.000	ENSOGAG00000027912	-	76	100.000	Otolemur_garnettii
ENSG00000110321	EIF4G2	100	100.000	ENSOARG00000010243	EIF4G2	96	99.780	Ovis_aries
ENSG00000110321	EIF4G2	100	100.000	ENSPPAG00000028909	EIF4G2	100	100.000	Pan_paniscus
ENSG00000110321	EIF4G2	100	100.000	ENSPPRG00000012435	EIF4G2	100	99.890	Panthera_pardus
ENSG00000110321	EIF4G2	100	100.000	ENSPTIG00000012255	EIF4G2	100	99.885	Panthera_tigris_altaica
ENSG00000110321	EIF4G2	100	100.000	ENSPTRG00000003362	EIF4G2	100	99.890	Pan_troglodytes
ENSG00000110321	EIF4G2	100	100.000	ENSPANG00000005223	EIF4G2	100	99.890	Papio_anubis
ENSG00000110321	EIF4G2	99	89.655	ENSPKIG00000022719	eif4g2b	95	84.034	Paramormyrops_kingsleyae
ENSG00000110321	EIF4G2	99	87.356	ENSPKIG00000011136	-	98	83.433	Paramormyrops_kingsleyae
ENSG00000110321	EIF4G2	100	93.443	ENSPSIG00000017589	EIF4G2	99	92.932	Pelodiscus_sinensis
ENSG00000110321	EIF4G2	97	63.768	ENSPMGG00000002065	eif4g2a	97	73.123	Periophthalmus_magnuspinnatus
ENSG00000110321	EIF4G2	99	88.506	ENSPMGG00000019907	eif4g2b	98	83.193	Periophthalmus_magnuspinnatus
ENSG00000110321	EIF4G2	100	100.000	ENSPEMG00000014969	Eif4g2	100	99.118	Peromyscus_maniculatus_bairdii
ENSG00000110321	EIF4G2	97	84.706	ENSPMAG00000003048	eif4g2a	98	64.238	Petromyzon_marinus
ENSG00000110321	EIF4G2	100	100.000	ENSPCIG00000024888	EIF4G2	96	98.346	Phascolarctos_cinereus
ENSG00000110321	EIF4G2	92	87.654	ENSPFOG00000011759	eif4g2a	98	73.046	Poecilia_formosa
ENSG00000110321	EIF4G2	100	88.115	ENSPFOG00000015554	eif4g2b	95	84.521	Poecilia_formosa
ENSG00000110321	EIF4G2	92	87.654	ENSPLAG00000019119	eif4g2a	96	72.529	Poecilia_latipinna
ENSG00000110321	EIF4G2	99	88.506	ENSPLAG00000019338	eif4g2b	98	85.012	Poecilia_latipinna
ENSG00000110321	EIF4G2	100	68.571	ENSPMEG00000014348	-	100	81.637	Poecilia_mexicana
ENSG00000110321	EIF4G2	100	68.571	ENSPMEG00000004642	eif4g2b	98	84.839	Poecilia_mexicana
ENSG00000110321	EIF4G2	95	86.905	ENSPMEG00000021509	eif4g2a	96	72.560	Poecilia_mexicana
ENSG00000110321	EIF4G2	100	88.115	ENSPREG00000003216	eif4g2b	98	84.892	Poecilia_reticulata
ENSG00000110321	EIF4G2	97	85.882	ENSPREG00000023123	eif4g2a	96	72.009	Poecilia_reticulata
ENSG00000110321	EIF4G2	100	100.000	ENSPPYG00000003485	EIF4G2	100	99.890	Pongo_abelii
ENSG00000110321	EIF4G2	100	99.645	ENSPCAG00000014863	EIF4G2	100	94.377	Procavia_capensis
ENSG00000110321	EIF4G2	100	86.190	ENSPCOG00000024084	-	97	90.557	Propithecus_coquereli
ENSG00000110321	EIF4G2	100	100.000	ENSPCOG00000025142	-	100	99.885	Propithecus_coquereli
ENSG00000110321	EIF4G2	100	99.890	ENSPVAG00000016828	EIF4G2	100	99.890	Pteropus_vampyrus
ENSG00000110321	EIF4G2	99	86.207	ENSPNYG00000012322	eif4g2b	95	84.951	Pundamilia_nyererei
ENSG00000110321	EIF4G2	97	83.529	ENSPNYG00000009089	eif4g2a	95	72.757	Pundamilia_nyererei
ENSG00000110321	EIF4G2	90	92.405	ENSPNAG00000017735	eif4g2b	98	83.475	Pygocentrus_nattereri
ENSG00000110321	EIF4G2	99	86.207	ENSPNAG00000003194	eif4g2a	98	83.553	Pygocentrus_nattereri
ENSG00000110321	EIF4G2	100	100.000	ENSRNOG00000017158	Eif4g2	100	99.118	Rattus_norvegicus
ENSG00000110321	EIF4G2	100	100.000	ENSRBIG00000028088	-	100	99.885	Rhinopithecus_bieti
ENSG00000110321	EIF4G2	99	97.701	ENSRBIG00000030029	-	99	98.270	Rhinopithecus_bieti
ENSG00000110321	EIF4G2	99	97.701	ENSRROG00000034661	-	100	97.312	Rhinopithecus_roxellana
ENSG00000110321	EIF4G2	100	100.000	ENSRROG00000037908	-	100	99.885	Rhinopithecus_roxellana
ENSG00000110321	EIF4G2	100	100.000	ENSSBOG00000026537	EIF4G2	100	99.890	Saimiri_boliviensis_boliviensis
ENSG00000110321	EIF4G2	100	99.225	ENSSHAG00000003530	EIF4G2	98	98.346	Sarcophilus_harrisii
ENSG00000110321	EIF4G2	91	91.250	ENSSFOG00015013848	EIF4G2	98	84.088	Scleropages_formosus
ENSG00000110321	EIF4G2	99	88.506	ENSSFOG00015004640	eif4g2b	96	83.094	Scleropages_formosus
ENSG00000110321	EIF4G2	99	85.057	ENSSMAG00000000556	eif4g2b	95	83.671	Scophthalmus_maximus
ENSG00000110321	EIF4G2	97	82.353	ENSSMAG00000021426	eif4g2a	94	71.742	Scophthalmus_maximus
ENSG00000110321	EIF4G2	97	84.706	ENSSDUG00000023332	eif4g2a	96	78.177	Seriola_dumerili
ENSG00000110321	EIF4G2	99	88.506	ENSSDUG00000004703	eif4g2b	96	85.971	Seriola_dumerili
ENSG00000110321	EIF4G2	97	84.706	ENSSLDG00000021890	eif4g2a	92	76.143	Seriola_lalandi_dorsalis
ENSG00000110321	EIF4G2	99	88.506	ENSSLDG00000023260	eif4g2b	96	85.971	Seriola_lalandi_dorsalis
ENSG00000110321	EIF4G2	100	87.619	ENSSARG00000010737	EIF4G2	90	99.251	Sorex_araneus
ENSG00000110321	EIF4G2	100	93.798	ENSSPUG00000013839	EIF4G2	99	94.519	Sphenodon_punctatus
ENSG00000110321	EIF4G2	99	88.506	ENSSPAG00000012058	eif4g2b	97	85.248	Stegastes_partitus
ENSG00000110321	EIF4G2	92	88.889	ENSSPAG00000012500	eif4g2a	95	71.478	Stegastes_partitus
ENSG00000110321	EIF4G2	99	66.667	ENSSSCG00000038354	-	98	61.754	Sus_scrofa
ENSG00000110321	EIF4G2	100	100.000	ENSSSCG00000013405	-	96	100.000	Sus_scrofa
ENSG00000110321	EIF4G2	99	94.253	ENSTGUG00000007840	EIF4G2	97	94.183	Taeniopygia_guttata
ENSG00000110321	EIF4G2	100	67.143	ENSTRUG00000012784	eif4g2b	97	81.884	Takifugu_rubripes
ENSG00000110321	EIF4G2	97	77.647	ENSTRUG00000017454	eif4g2a	97	72.115	Takifugu_rubripes
ENSG00000110321	EIF4G2	99	86.879	ENSTNIG00000013720	eif4g2b	99	82.739	Tetraodon_nigroviridis
ENSG00000110321	EIF4G2	100	100.000	ENSTBEG00000000475	EIF4G2	98	86.353	Tupaia_belangeri
ENSG00000110321	EIF4G2	100	88.093	ENSTTRG00000014047	EIF4G2	100	88.093	Tursiops_truncatus
ENSG00000110321	EIF4G2	100	100.000	ENSUAMG00000021122	EIF4G2	100	99.715	Ursus_americanus
ENSG00000110321	EIF4G2	100	100.000	ENSUMAG00000015347	EIF4G2	99	99.890	Ursus_maritimus
ENSG00000110321	EIF4G2	100	100.000	ENSVPAG00000010174	EIF4G2	100	99.011	Vicugna_pacos
ENSG00000110321	EIF4G2	99	100.000	ENSVVUG00000025335	EIF4G2	100	99.890	Vulpes_vulpes
ENSG00000110321	EIF4G2	99	89.655	ENSXETG00000013674	eif4g2	96	86.239	Xenopus_tropicalis
ENSG00000110321	EIF4G2	99	88.506	ENSXCOG00000003655	eif4g2b	98	84.652	Xiphophorus_couchianus
ENSG00000110321	EIF4G2	99	88.506	ENSXMAG00000013534	eif4g2b	98	84.652	Xiphophorus_maculatus
ENSG00000110321	EIF4G2	95	83.333	ENSXMAG00000009265	eif4g2a	96	71.609	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0003723	RNA binding	22658674.22681889.	HDA	Function
GO:0003729	mRNA binding	21873635.	IBA	Function
GO:0003743	translation initiation factor activity	21873635.	IBA	Function
GO:0003743	translation initiation factor activity	11943866.	IDA	Function
GO:0005515	protein binding	16166382.16932749.21911577.25277244.	IPI	Function
GO:0005829	cytosol	-	IDA	Component
GO:0005829	cytosol	-	TAS	Component
GO:0005913	cell-cell adherens junction	25468996.	HDA	Component
GO:0006413	translational initiation	-	IEA	Process
GO:0006446	regulation of translational initiation	11943866.	IDA	Process
GO:0007050	cell cycle arrest	9032289.	TAS	Process
GO:0008135	translation factor activity, RNA binding	16289705.	IDA	Function
GO:0008219	cell death	9032289.	TAS	Process
GO:0010507	negative regulation of autophagy	18426977.	IMP	Process
GO:0016020	membrane	19946888.	HDA	Component
GO:0016281	eukaryotic translation initiation factor 4F complex	21873635.	IBA	Component
GO:0016281	eukaryotic translation initiation factor 4F complex	11943866.	IDA	Component
GO:0030307	positive regulation of cell growth	18426977.	IMP	Process
GO:0034645	cellular macromolecule biosynthetic process	18426977.	IGI	Process
GO:0045296	cadherin binding	25468996.	HDA	Function