Description
Ensembl ID
ENSG00000110871 (Gene tree)
Gene ID
84274
Gene Symbol
COQ5
Alias
MGC4767
Full Name
coenzyme Q5, methyltransferase
Gene Type
protein_coding
Species
Homo_sapiens
Status
putative
Strand
Minus strand
Length
31,161 bases
Position
chr12:120,503,274-120,534,434
Accession
28722
RBP type
canonical RBP
Summary
COQ5 (Coenzyme Q5, Methyltransferase) is a Protein Coding gene. Diseases associated with COQ5 include Coenzyme Q10 Deficiency, Primary, 4 and Coenzyme Q10 Deficiency Disease. Among its related pathways are Metabolism and Ubiquinol biosynthesis. Gene Ontology (GO) annotations related to this gene include methyltransferase activity and S-adenosylmethionine-dependent methyltransferase activity. An important paralog of this gene is AS3MT.
RNA binding domains(RBDs)
Protein ID
Domain
Pfam ID
E-value
Domain number
Total number
ENSP00000449863Methyltransf_31PF13847.67.4e-1311
ENSP00000288532Methyltransf_31PF13847.61.8e-1211
ENSP00000401798Methyltransf_31PF13847.62.5e-0611
Expression
Adipose_TissueAdrenal_GlandBladderBloodBlood_VesselBrainBreastCervix_UteriColonEsophagusFallopian_TubeHeartKidneyLiverLungMuscleNerveOvaryPancreasPituitaryProstateSalivary_GlandSkinSmall_IntestineSpleenStomachTestisThyroidUterusVagina020406080
Adipose_TissueAdrenal_GlandBladderBloodBlood_VesselBrainBreastCervix_UteriColonEsophagusFallopian_TubeHeartKidneyLiverLungMuscleNerveOvaryPancreasPituitaryProstateSalivary_GlandSkinSmall_IntestineSpleenStomachTestisThyroidUterusVaginaTPM
Transcripts
Transcript ID
Name
Length
RefSeq ID
Protein ID
Length
RefSeq ID
UniportKB ID
ENST00000547448COQ5-204701--- (aa)--
ENST00000551769COQ5-207560-ENSP00000450001130 (aa)-F8VP53
ENST00000547736COQ5-205574-ENSP0000044993391 (aa)-F8VVD5
ENST00000546838COQ5-203391--- (aa)--
ENST00000445328COQ5-202992-ENSP00000401798253 (aa)-B4DP72
ENST00000288532COQ5-2011535-ENSP00000288532327 (aa)-Q5HYK3
ENST00000552443COQ5-208972XM_006719639ENSP00000449863213 (aa)XP_006719702F8VVX6
ENST00000547943COQ5-206552-ENSP00000449874176 (aa)-F8VVW7
Pathways
Pathway ID
Pathway Name
Source
hsa00130Ubiquinone and other terpenoid-quinone biosynthesisKEGG
hsa01100Metabolic pathwaysKEGG
GWAS
ensgID
SNP
Chromosome
Position
SNP-risk
Trait
PubmedID
95% CI
Or or BEAT
EFO ID
ENSG00000110871rs167177012120508765AEducational attainment (years of education)30038396[0.009-0.016] unit increase0.0125EFO_0004784
Protein-Protein Interaction (PPI)


CanvasJS.com
* RBP PPI network refers to all genes directly bind to RBP
Orthologs
Ensembl ID
Gene Symbol
Coverage
Identiy
Ortholog
Gene Symbol
Coverage
Identiy
Species
ENSG00000110871COQ510074.178ENSAPOG00000023210coq58971.379Acanthochromis_polyacanthus
ENSG00000110871COQ510093.897ENSAMEG00000013273COQ510089.908Ailuropoda_melanoleuca
ENSG00000110871COQ510076.168ENSACIG00000002411coq59072.664Amphilophus_citrinellus
ENSG00000110871COQ510074.648ENSAOCG00000010810coq58872.222Amphiprion_ocellaris
ENSG00000110871COQ510075.117ENSAPEG00000011317coq58872.569Amphiprion_percula
ENSG00000110871COQ510072.897ENSATEG00000005524coq59169.000Anabas_testudineus
ENSG00000110871COQ510077.570ENSAPLG00000015103COQ510078.161Anas_platyrhynchos
ENSG00000110871COQ510078.505ENSACAG00000002934COQ59974.920Anolis_carolinensis
ENSG00000110871COQ510097.653ENSANAG00000038352COQ510095.107Aotus_nancymaae
ENSG00000110871COQ510074.766ENSACLG00000023616coq59071.724Astatotilapia_calliptera
ENSG00000110871COQ510070.423ENSAMXG00000001845coq58969.178Astyanax_mexicanus
ENSG00000110871COQ510092.488ENSBTAG00000015761COQ59989.602Bos_taurus
ENSG00000110871COQ510044.240WBGene00000765coq-58945.862Caenorhabditis_elegans
ENSG00000110871COQ510098.122ENSCJAG00000001205COQ510094.495Callithrix_jacchus
ENSG00000110871COQ510093.427ENSCAFG00000010338COQ510089.297Canis_familiaris
ENSG00000110871COQ510093.427ENSCAFG00020020629COQ510089.297Canis_lupus_dingo
ENSG00000110871COQ510093.427ENSCHIG00000019366COQ510090.214Capra_hircus
ENSG00000110871COQ510092.019ENSTSYG00000007068COQ510090.514Carlito_syrichta
ENSG00000110871COQ510085.385ENSCAPG00000015454-10086.170Cavia_aperea
ENSG00000110871COQ510089.671ENSCPOG00000031239COQ510086.544Cavia_porcellus
ENSG00000110871COQ510097.653ENSCCAG00000010621COQ510095.413Cebus_capucinus
ENSG00000110871COQ510098.122ENSCATG00000031184COQ510095.719Cercocebus_atys
ENSG00000110871COQ510091.549ENSCLAG00000011645COQ510087.768Chinchilla_lanigera
ENSG00000110871COQ510098.122ENSCSAG00000002254COQ510096.636Chlorocebus_sabaeus
ENSG00000110871COQ59388.971ENSCPBG00000011334COQ59775.161Chrysemys_picta_bellii
ENSG00000110871COQ510053.521ENSCING00000023156-9850.825Ciona_intestinalis
ENSG00000110871COQ510089.671ENSCGRG00001009849COQ510086.544Cricetulus_griseus_chok1gshd
ENSG00000110871COQ510089.671ENSCGRG00000014128COQ510086.544Cricetulus_griseus_crigri
ENSG00000110871COQ510073.709ENSCVAG00000017359coq58970.000Cyprinodon_variegatus
ENSG00000110871COQ510071.362ENSDARG00000035618coq58970.103Danio_rerio
ENSG00000110871COQ510094.161ENSDNOG00000012631COQ59988.379Dasypus_novemcinctus
ENSG00000110871COQ510092.019ENSDORG00000006156Coq510087.462Dipodomys_ordii
ENSG00000110871COQ510050.228FBgn0030460CG24538554.255Drosophila_melanogaster
ENSG00000110871COQ510089.671ENSETEG00000009271COQ59886.120Echinops_telfairi
ENSG00000110871COQ510063.889ENSEBUG00000013346coq59763.889Eptatretus_burgeri
ENSG00000110871COQ510094.366ENSEASG00005004720COQ59391.743Equus_asinus_asinus
ENSG00000110871COQ510094.836ENSECAG00000006182COQ59391.437Equus_caballus
ENSG00000110871COQ59477.703ENSELUG00000005161coq59265.831Esox_lucius
ENSG00000110871COQ510092.488ENSFCAG00000011014COQ510091.304Felis_catus
ENSG00000110871COQ510078.037ENSFALG00000007553COQ59773.267Ficedula_albicollis
ENSG00000110871COQ510092.019ENSFDAG00000012097COQ510088.073Fukomys_damarensis
ENSG00000110871COQ510072.770ENSFHEG00000005200coq58270.242Fundulus_heteroclitus
ENSG00000110871COQ510069.907ENSGMOG00000009291coq59367.000Gadus_morhua
ENSG00000110871COQ510078.505ENSGALG00000007185COQ59575.338Gallus_gallus
ENSG00000110871COQ510071.362ENSGAFG00000006646coq59268.000Gambusia_affinis
ENSG00000110871COQ510072.350ENSGACG00000014667coq59069.928Gasterosteus_aculeatus
ENSG00000110871COQ510081.308ENSGAGG00000016013COQ58880.645Gopherus_agassizii
ENSG00000110871COQ510099.231ENSGGOG00000008795COQ510097.859Gorilla_gorilla
ENSG00000110871COQ510074.299ENSHBUG00000010344coq59071.379Haplochromis_burtoni
ENSG00000110871COQ510091.549ENSHGLG00000013064COQ510087.768Heterocephalus_glaber_female
ENSG00000110871COQ510091.549ENSHGLG00100017091COQ510087.768Heterocephalus_glaber_male
ENSG00000110871COQ510067.606ENSHCOG00000014865coq58865.398Hippocampus_comes
ENSG00000110871COQ510070.423ENSIPUG00000018269coq58570.652Ictalurus_punctatus
ENSG00000110871COQ510092.488ENSSTOG00000012560COQ510089.602Ictidomys_tridecemlineatus
ENSG00000110871COQ510088.732ENSJJAG00000021649Coq510084.709Jaculus_jaculus
ENSG00000110871COQ510070.892ENSKMAG00000002063coq58869.338Kryptolebias_marmoratus
ENSG00000110871COQ510072.430ENSLBEG00000008182coq58672.563Labrus_bergylta
ENSG00000110871COQ510074.766ENSLACG00000018210COQ59674.460Latimeria_chalumnae
ENSG00000110871COQ510091.080ENSLAFG00000006646COQ510088.685Loxodonta_africana
ENSG00000110871COQ510098.592ENSMFAG00000038162COQ510097.248Macaca_fascicularis
ENSG00000110871COQ510098.592ENSMMUG00000020601COQ510097.248Macaca_mulatta
ENSG00000110871COQ510097.653ENSMLEG00000021232COQ510097.233Mandrillus_leucophaeus
ENSG00000110871COQ510073.023ENSMAMG00000004052coq58870.103Mastacembelus_armatus
ENSG00000110871COQ510074.766ENSMZEG00005021784coq59071.724Maylandia_zebra
ENSG00000110871COQ510078.972ENSMGAG00000008710COQ59977.985Meleagris_gallopavo
ENSG00000110871COQ510089.202ENSMAUG00000007966Coq510086.544Mesocricetus_auratus
ENSG00000110871COQ510093.427ENSMICG00000006371-10085.321Microcebus_murinus
ENSG00000110871COQ59776.329ENSMICG00000033773-9973.313Microcebus_murinus
ENSG00000110871COQ510089.671ENSMOCG00000022159Coq510086.239Microtus_ochrogaster
ENSG00000110871COQ510073.364ENSMMOG00000000532coq59169.103Mola_mola
ENSG00000110871COQ59693.600ENSMODG00000003124COQ59577.532Monodelphis_domestica
ENSG00000110871COQ510072.685ENSMALG00000001130coq58870.205Monopterus_albus
ENSG00000110871COQ510087.324MGP_CAROLIEiJ_G0027620Coq510084.098Mus_caroli
ENSG00000110871COQ510088.732ENSMUSG00000041733Coq510083.792Mus_musculus
ENSG00000110871COQ510076.836MGP_PahariEiJ_G0024200-10069.817Mus_pahari
ENSG00000110871COQ510088.263MGP_SPRETEiJ_G0028618Coq510083.792Mus_spretus
ENSG00000110871COQ510091.080ENSMPUG00000003212COQ510086.544Mustela_putorius_furo
ENSG00000110871COQ510089.831ENSMLUG00000014636COQ510088.991Myotis_lucifugus
ENSG00000110871COQ510091.538ENSNGAG00000020139Coq510085.627Nannospalax_galili
ENSG00000110871COQ510074.299ENSNBRG00000015707coq58673.563Neolamprologus_brichardi
ENSG00000110871COQ510099.231ENSNLEG00000015685COQ510097.248Nomascus_leucogenys
ENSG00000110871COQ59797.037ENSOPRG00000004269COQ57597.037Ochotona_princeps
ENSG00000110871COQ510091.080ENSODEG00000006329COQ510085.933Octodon_degus
ENSG00000110871COQ510075.234ENSONIG00000010541coq59071.875Oreochromis_niloticus
ENSG00000110871COQ510089.130ENSOANG00000001789COQ510075.758Ornithorhynchus_anatinus
ENSG00000110871COQ510092.488ENSOCUG00000014871COQ510088.073Oryctolagus_cuniculus
ENSG00000110871COQ510070.370ENSORLG00000001215coq58270.968Oryzias_latipes
ENSG00000110871COQ510044.776ENSORLG00020009529coq56450.870Oryzias_latipes_hni
ENSG00000110871COQ510048.507ENSORLG00020009446coq57553.043Oryzias_latipes_hni
ENSG00000110871COQ510070.370ENSORLG00020009640coq58270.609Oryzias_latipes_hni
ENSG00000110871COQ510069.444ENSORLG00015000685coq58170.251Oryzias_latipes_hsok
ENSG00000110871COQ58249.138ENSOMEG00000008270-7657.317Oryzias_melastigma
ENSG00000110871COQ59960.150ENSOMEG00000012618-9658.392Oryzias_melastigma
ENSG00000110871COQ510071.429ENSOMEG00000000317coq59268.814Oryzias_melastigma
ENSG00000110871COQ510092.488ENSOGAG00000008517COQ510090.826Otolemur_garnettii
ENSG00000110871COQ510093.427ENSOARG00000012543COQ510089.666Ovis_aries
ENSG00000110871COQ510099.531ENSPPAG00000029080COQ510098.777Pan_paniscus
ENSG00000110871COQ510092.958ENSPPRG00000003370COQ510091.700Panthera_pardus
ENSG00000110871COQ510092.958ENSPTIG00000010765COQ510091.700Panthera_tigris_altaica
ENSG00000110871COQ510099.531ENSPTRG00000005539COQ510098.777Pan_troglodytes
ENSG00000110871COQ510098.122ENSPANG00000005880COQ510097.233Papio_anubis
ENSG00000110871COQ510071.495ENSPKIG00000009514coq59266.212Paramormyrops_kingsleyae
ENSG00000110871COQ510077.523ENSPSIG00000013600COQ59978.491Pelodiscus_sinensis
ENSG00000110871COQ510072.430ENSPMGG00000022254coq58871.379Periophthalmus_magnuspinnatus
ENSG00000110871COQ510089.671ENSPEMG00000011721Coq510086.890Peromyscus_maniculatus_bairdii
ENSG00000110871COQ510067.593ENSPMAG00000002581coq510068.061Petromyzon_marinus
ENSG00000110871COQ510091.912ENSPCIG00000025993COQ510078.287Phascolarctos_cinereus
ENSG00000110871COQ510071.831ENSPFOG00000014445coq59268.333Poecilia_formosa
ENSG00000110871COQ510071.831ENSPLAG00000005478coq59268.333Poecilia_latipinna
ENSG00000110871COQ510071.831ENSPMEG00000016674coq59268.333Poecilia_mexicana
ENSG00000110871COQ510070.892ENSPREG00000004349coq59267.667Poecilia_reticulata
ENSG00000110871COQ510090.826ENSPPYG00000005034COQ510090.826Pongo_abelii
ENSG00000110871COQ510090.141ENSPCAG00000004983COQ510090.734Procavia_capensis
ENSG00000110871COQ510094.595ENSPCOG00000023183COQ510093.281Propithecus_coquereli
ENSG00000110871COQ510090.141ENSPVAG00000002231COQ510089.602Pteropus_vampyrus
ENSG00000110871COQ510074.766ENSPNYG00000007613coq58673.946Pundamilia_nyererei
ENSG00000110871COQ510087.324ENSRNOG00000001171Coq510085.627Rattus_norvegicus
ENSG00000110871COQ510097.183ENSRBIG00000031157COQ59992.638Rhinopithecus_bieti
ENSG00000110871COQ510098.122ENSRROG00000038268COQ510095.413Rhinopithecus_roxellana
ENSG00000110871COQ510042.152YML110CCOQ59342.724Saccharomyces_cerevisiae
ENSG00000110871COQ57897.297ENSSBOG00000024153COQ59095.652Saimiri_boliviensis_boliviensis
ENSG00000110871COQ510093.382ENSSHAG00000004267COQ510077.676Sarcophilus_harrisii
ENSG00000110871COQ510072.300ENSSFOG00015019599coq58964.923Scleropages_formosus
ENSG00000110871COQ510071.296ENSSMAG00000012894coq58868.493Scophthalmus_maximus
ENSG00000110871COQ510075.701ENSSDUG00000017858coq58872.414Seriola_dumerili
ENSG00000110871COQ510075.234ENSSLDG00000015028coq58872.069Seriola_lalandi_dorsalis
ENSG00000110871COQ510079.439ENSSPUG00000015661COQ58979.928Sphenodon_punctatus
ENSG00000110871COQ510091.080ENSSSCG00000009903COQ59387.768Sus_scrofa
ENSG00000110871COQ510078.505ENSTGUG00000009568COQ510077.698Taeniopygia_guttata
ENSG00000110871COQ510071.028ENSTRUG00000016150coq58869.310Takifugu_rubripes
ENSG00000110871COQ510071.831ENSTNIG00000015624coq58868.858Tetraodon_nigroviridis
ENSG00000110871COQ510084.507ENSTTRG00000000147COQ510083.792Tursiops_truncatus
ENSG00000110871COQ510092.488ENSUAMG00000015538COQ510088.991Ursus_americanus
ENSG00000110871COQ510092.019ENSUMAG00000006144COQ59688.073Ursus_maritimus
ENSG00000110871COQ510093.427ENSVPAG00000010363COQ510088.685Vicugna_pacos
ENSG00000110871COQ510093.427ENSVVUG00000021074COQ510088.991Vulpes_vulpes
ENSG00000110871COQ510086.029ENSXETG00000012228coq510067.976Xenopus_tropicalis
ENSG00000110871COQ510071.362ENSXCOG00000010399coq59267.333Xiphophorus_couchianus
ENSG00000110871COQ510071.362ENSXMAG00000002674coq59066.438Xiphophorus_maculatus
Gene Ontology
Go ID
Go_term
PubmedID
Evidence
Category
GO:0005515protein binding25152161.27499296.IPIFunction
GO:0005739mitochondrion21873635.IBAComponent
GO:0005743mitochondrial inner membrane25152161.IDAComponent
GO:0005759mitochondrial matrix25152161.IDAComponent
GO:0006744ubiquinone biosynthetic process-IEAProcess
GO:0006744ubiquinone biosynthetic process25152161.IGIProcess
GO:0031314extrinsic component of mitochondrial inner membrane-IEAComponent
GO:0032259methylation25152161.IDAProcess
GO:0032991protein-containing complex25152161.IDAComponent
GO:00433332-octaprenyl-6-methoxy-1,4-benzoquinone methylase activity25152161.IDAFunction
GO:00434302-decaprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity-IEAFunction
Mpgyi