EuRBPDB

Description

RBDs

RBPome

PRI

Literatures

Expression

Transcripts

Gene Model

Pathways

Phenotypes

GWAS

PPI

Paralogs

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000111605 (Gene tree)
Gene ID: 11052
Gene Symbol: CPSF6
Alias: CFIM|HPBRII-4|HPBRII-7|CFIM68|CFIM72
Full Name: cleavage and polyadenylation specific factor 6
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Plus strand
Length: 34,822 bases
Position: chr12:69,239,537-69,274,358
Accession: 13871
RBP type: canonical RBP
Summary: The protein encoded by this gene is one subunit of a cleavage factor required for 3' RNA cleavage and polyadenylation processing. The interaction of the protein with the RNA is one of the earliest steps in the assembly of the 3' end processing complex and facilitates the recruitment of other processing factors. The cleavage factor complex is composed of four polypeptides. This gene encodes the 68kD subunit. It has a domain organization reminiscent of spliceosomal proteins. [provided by RefSeq, Jul 2008]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000391437	RRM_1	PF00076.22	2.6e-06	1	1
ENSP00000391774	RRM_1	PF00076.22	3.3e-06	1	1
ENSP00000266679	RRM_1	PF00076.22	3.6e-06	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
22681889	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts	4SURIC & HEK293	2012 May	Baltz AG	DOI: 10.1016/j.molcel.2012.05.021
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
29431736	Capturing the interactome of newly transcribed RNA	PolyT-RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	RIC & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
22658674	Insights into RNA biology from an atlas of mammalian mRNA-binding proteins	RIC & Hela	2012 May 31	Castello A	DOI: 10.1016/j.cell.2012.04.031
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30352994	Discovery of RNA-binding proteins and characterization of their dynamic responses by enhanced RNA interactome capture	RIC & Jurkat	2018 Oct 23	Perez-Perri JI	DOI:10.1038/s41467-018-06557-8

Protein-RNA interaction（RNA-Binding Site）

Click here to download all RNA binding sites

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
29606597	The TORC1-Regulated CPA Complex Rewires an RNA Processing Network to Drive Autophagy and Metabolic Reprogramming.	Cell Metab	2018 May 1	Tang HW	doi: 10.1016/j.cmet.2018.02.023
28053162	POSTAR: a platform for exploring post-transcriptional regulation coordinated by RNA-binding proteins.	Nucleic Acids Res	2017 Jan 4	Hu B	doi: 10.1093/nar/gkw888
22956906	CPSF6 defines a conserved capsid interface that modulates HIV-1 replication.	PLoS Pathog	2012	Price AJ	doi: 10.1371/journal.ppat.1002896
24142921	Identification and characterization of FGF2-dependent mRNA: microRNA networks during lens fiber cell differentiation.	G3 (Bethesda)	2013 Dec 9	Wolf L	doi: 10.1534/g3.113.008698.

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000547486	CPSF6-204	872	-	-	- (aa)	-	-
ENST00000551516	CPSF6-207	234	-	ENSP00000450206	56 (aa)	-	F8VNP8
ENST00000650046	CPSF6-208	7525	-	ENSP00000497420	165 (aa)	-	-
ENST00000550987	CPSF6-206	560	-	-	- (aa)	-	-
ENST00000266679	CPSF6-201	2229	XM_005268588	ENSP00000266679	588 (aa)	XP_005268645	Q16630
ENST00000456847	CPSF6-203	1915	-	ENSP00000391437	478 (aa)	-	F8WJN3
ENST00000550075	CPSF6-205	540	-	ENSP00000446670	107 (aa)	-	F8W084
ENST00000435070	CPSF6-202	6616	XM_005268590	ENSP00000391774	551 (aa)	XP_005268647	Q16630

Gene Model

Click here to download ENSG00000111605's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa03015	mRNA surveillance pathway	KEGG

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000111605	Neuroticism	8.459e-005	-

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000111605	rs7969559	12	69261387	?	Smoking status	30595370			EFO_0006527
ENSG00000111605	rs317630	12	69244067	T	Osteoarthritis	30664745	[1.02-1.05]	1.04	EFO_0002506
ENSG00000111605	rs7969559	12	69261387	G	Smoking initiation (ever regular vs never regular) (MTAG)	30643251	[0.0057-0.0104] unit decrease	0.00803583	EFO_0006527
ENSG00000111605	rs7969559	12	69261387	G	Smoking initiation (ever regular vs never regular)	30643251	[0.011-0.023] unit decrease	0.017015876	EFO_0006527

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000111605's network

* RBP PPI network refers to all genes directly bind to RBP

Paralogs

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy
ENSG00000111605	CPSF6	95	46.234	ENSG00000149532	CPSF7	100	54.598

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000111605	CPSF6	100	99.830	ENSAMEG00000011781	CPSF6	100	99.830	Ailuropoda_melanoleuca
ENSG00000111605	CPSF6	95	43.920	ENSAMEG00000016595	CPSF7	67	55.814	Ailuropoda_melanoleuca
ENSG00000111605	CPSF6	88	80.851	ENSAOCG00000017865	cpsf6	94	82.792	Amphiprion_ocellaris
ENSG00000111605	CPSF6	88	93.617	ENSACAG00000004381	CPSF6	53	95.775	Anolis_carolinensis
ENSG00000111605	CPSF6	97	100.000	ENSANAG00000019240	CPSF6	99	100.000	Aotus_nancymaae
ENSG00000111605	CPSF6	93	41.770	ENSANAG00000024635	CPSF7	69	50.276	Aotus_nancymaae
ENSG00000111605	CPSF6	93	85.271	ENSACLG00000026325	cpsf6	77	85.441	Astatotilapia_calliptera
ENSG00000111605	CPSF6	88	75.532	ENSAMXG00000016745	CPSF6	75	89.091	Astyanax_mexicanus
ENSG00000111605	CPSF6	100	100.000	ENSBTAG00000007323	CPSF6	100	100.000	Bos_taurus
ENSG00000111605	CPSF6	95	45.585	ENSBTAG00000015263	CPSF7	71	55.429	Bos_taurus
ENSG00000111605	CPSF6	95	46.234	ENSCJAG00000019282	CPSF7	84	54.857	Callithrix_jacchus
ENSG00000111605	CPSF6	100	100.000	ENSCJAG00000001798	CPSF6	100	100.000	Callithrix_jacchus
ENSG00000111605	CPSF6	97	100.000	ENSCAFG00000000424	CPSF6	100	100.000	Canis_familiaris
ENSG00000111605	CPSF6	95	45.585	ENSCAFG00000016152	CPSF7	71	56.000	Canis_familiaris
ENSG00000111605	CPSF6	100	100.000	ENSCAFG00020016950	CPSF6	100	100.000	Canis_lupus_dingo
ENSG00000111605	CPSF6	95	45.585	ENSCAFG00020012753	CPSF7	71	56.000	Canis_lupus_dingo
ENSG00000111605	CPSF6	100	100.000	ENSCHIG00000010792	CPSF6	100	100.000	Capra_hircus
ENSG00000111605	CPSF6	95	45.585	ENSCHIG00000014655	CPSF7	71	55.429	Capra_hircus
ENSG00000111605	CPSF6	95	45.585	ENSTSYG00000010138	-	71	56.000	Carlito_syrichta
ENSG00000111605	CPSF6	97	100.000	ENSTSYG00000008591	CPSF6	100	100.000	Carlito_syrichta
ENSG00000111605	CPSF6	90	44.516	ENSCAPG00000006384	CPSF7	70	56.000	Cavia_aperea
ENSG00000111605	CPSF6	95	45.585	ENSCPOG00000009980	CPSF7	71	56.000	Cavia_porcellus
ENSG00000111605	CPSF6	100	99.819	ENSCPOG00000015201	CPSF6	100	99.819	Cavia_porcellus
ENSG00000111605	CPSF6	100	100.000	ENSCCAG00000028149	CPSF6	100	100.000	Cebus_capucinus
ENSG00000111605	CPSF6	95	45.380	ENSCCAG00000032367	CPSF7	71	55.429	Cebus_capucinus
ENSG00000111605	CPSF6	100	100.000	ENSCATG00000039288	CPSF6	100	100.000	Cercocebus_atys
ENSG00000111605	CPSF6	95	46.234	ENSCATG00000042801	CPSF7	77	55.429	Cercocebus_atys
ENSG00000111605	CPSF6	97	99.648	ENSCLAG00000010149	CPSF6	100	99.812	Chinchilla_lanigera
ENSG00000111605	CPSF6	95	45.585	ENSCLAG00000003174	CPSF7	71	55.429	Chinchilla_lanigera
ENSG00000111605	CPSF6	95	46.234	ENSCSAG00000006414	CPSF7	77	55.429	Chlorocebus_sabaeus
ENSG00000111605	CPSF6	100	100.000	ENSCSAG00000004232	CPSF6	100	100.000	Chlorocebus_sabaeus
ENSG00000111605	CPSF6	100	98.004	ENSCPBG00000013322	CPSF6	100	98.004	Chrysemys_picta_bellii
ENSG00000111605	CPSF6	88	37.234	ENSCSAVG00000000161	-	70	52.023	Ciona_savignyi
ENSG00000111605	CPSF6	97	100.000	ENSCANG00000037294	CPSF6	100	100.000	Colobus_angolensis_palliatus
ENSG00000111605	CPSF6	95	45.791	ENSCGRG00001020382	Cpsf7	71	57.714	Cricetulus_griseus_chok1gshd
ENSG00000111605	CPSF6	100	100.000	ENSCGRG00001018082	Cpsf6	100	100.000	Cricetulus_griseus_chok1gshd
ENSG00000111605	CPSF6	95	47.083	ENSCGRG00000017954	Cpsf7	77	57.714	Cricetulus_griseus_crigri
ENSG00000111605	CPSF6	97	100.000	ENSCGRG00000016909	Cpsf6	100	100.000	Cricetulus_griseus_crigri
ENSG00000111605	CPSF6	69	34.337	ENSCSEG00000001956	CPSF7	57	46.154	Cynoglossus_semilaevis
ENSG00000111605	CPSF6	93	84.375	ENSCSEG00000008967	cpsf6	94	82.792	Cynoglossus_semilaevis
ENSG00000111605	CPSF6	94	77.438	ENSCVAG00000014857	cpsf6	94	79.541	Cyprinodon_variegatus
ENSG00000111605	CPSF6	87	32.037	ENSCVAG00000007392	CPSF7	52	45.745	Cyprinodon_variegatus
ENSG00000111605	CPSF6	88	78.723	ENSDARG00000018618	cpsf6	69	89.091	Danio_rerio
ENSG00000111605	CPSF6	95	45.585	ENSDNOG00000018517	CPSF7	84	55.429	Dasypus_novemcinctus
ENSG00000111605	CPSF6	100	99.457	ENSDNOG00000015292	CPSF6	100	99.457	Dasypus_novemcinctus
ENSG00000111605	CPSF6	97	100.000	ENSDORG00000002950	Cpsf6	100	100.000	Dipodomys_ordii
ENSG00000111605	CPSF6	76	39.310	FBgn0035872	CG7185	57	53.049	Drosophila_melanogaster
ENSG00000111605	CPSF6	95	45.248	ENSETEG00000003765	CPSF7	71	56.725	Echinops_telfairi
ENSG00000111605	CPSF6	100	92.857	ENSETEG00000002097	CPSF6	100	92.857	Echinops_telfairi
ENSG00000111605	CPSF6	100	100.000	ENSEASG00005008066	CPSF6	100	100.000	Equus_asinus_asinus
ENSG00000111605	CPSF6	95	45.585	ENSEASG00005008196	CPSF7	71	56.000	Equus_asinus_asinus
ENSG00000111605	CPSF6	100	100.000	ENSECAG00000015988	CPSF6	100	100.000	Equus_caballus
ENSG00000111605	CPSF6	83	53.297	ENSECAG00000018521	CPSF7	95	55.429	Equus_caballus
ENSG00000111605	CPSF6	55	62.069	ENSEEUG00000005966	-	66	61.017	Erinaceus_europaeus
ENSG00000111605	CPSF6	97	99.296	ENSEEUG00000015039	CPSF6	100	99.296	Erinaceus_europaeus
ENSG00000111605	CPSF6	95	45.585	ENSFCAG00000013677	CPSF7	95	55.429	Felis_catus
ENSG00000111605	CPSF6	100	99.830	ENSFCAG00000002855	CPSF6	100	99.830	Felis_catus
ENSG00000111605	CPSF6	97	98.124	ENSFALG00000010157	CPSF6	100	98.124	Ficedula_albicollis
ENSG00000111605	CPSF6	95	42.283	ENSFALG00000011927	CPSF7	76	56.395	Ficedula_albicollis
ENSG00000111605	CPSF6	95	45.399	ENSFDAG00000003919	CPSF7	71	56.000	Fukomys_damarensis
ENSG00000111605	CPSF6	99	97.268	ENSFDAG00000002281	CPSF6	99	97.268	Fukomys_damarensis
ENSG00000111605	CPSF6	94	74.410	ENSFHEG00000019693	cpsf6	95	77.314	Fundulus_heteroclitus
ENSG00000111605	CPSF6	88	78.723	ENSGMOG00000012951	cpsf6	53	92.500	Gadus_morhua
ENSG00000111605	CPSF6	95	47.170	ENSGALG00000040962	CPSF7	63	56.647	Gallus_gallus
ENSG00000111605	CPSF6	100	98.004	ENSGAGG00000010228	CPSF6	100	98.004	Gopherus_agassizii
ENSG00000111605	CPSF6	100	99.830	ENSGGOG00000008211	CPSF6	100	99.830	Gorilla_gorilla
ENSG00000111605	CPSF6	93	85.271	ENSHBUG00000005998	cpsf6	94	81.453	Haplochromis_burtoni
ENSG00000111605	CPSF6	100	99.819	ENSHGLG00000000792	CPSF6	100	99.819	Heterocephalus_glaber_female
ENSG00000111605	CPSF6	95	46.653	ENSHGLG00000019090	-	77	56.000	Heterocephalus_glaber_female
ENSG00000111605	CPSF6	87	55.897	ENSHGLG00100013933	-	78	56.000	Heterocephalus_glaber_male
ENSG00000111605	CPSF6	97	99.472	ENSHGLG00100013861	CPSF6	100	99.812	Heterocephalus_glaber_male
ENSG00000111605	CPSF6	92	82.447	ENSHCOG00000014555	cpsf6	81	82.564	Hippocampus_comes
ENSG00000111605	CPSF6	95	45.585	ENSSTOG00000007708	CPSF7	71	56.000	Ictidomys_tridecemlineatus
ENSG00000111605	CPSF6	98	98.621	ENSSTOG00000014133	CPSF6	100	100.000	Ictidomys_tridecemlineatus
ENSG00000111605	CPSF6	95	46.444	ENSJJAG00000019390	Cpsf7	77	56.000	Jaculus_jaculus
ENSG00000111605	CPSF6	97	100.000	ENSJJAG00000014647	Cpsf6	100	100.000	Jaculus_jaculus
ENSG00000111605	CPSF6	88	79.787	ENSKMAG00000014794	cpsf6	61	86.667	Kryptolebias_marmoratus
ENSG00000111605	CPSF6	82	40.341	ENSLBEG00000000947	CPSF7	85	33.010	Labrus_bergylta
ENSG00000111605	CPSF6	88	80.851	ENSLBEG00000015762	cpsf6	77	81.992	Labrus_bergylta
ENSG00000111605	CPSF6	94	93.090	ENSLACG00000008625	CPSF6	94	93.282	Latimeria_chalumnae
ENSG00000111605	CPSF6	93	37.901	ENSLACG00000005542	CPSF7	70	44.304	Latimeria_chalumnae
ENSG00000111605	CPSF6	88	86.170	ENSLOCG00000016190	cpsf6	66	92.353	Lepisosteus_oculatus
ENSG00000111605	CPSF6	88	55.897	ENSLAFG00000032084	CPSF7	71	56.571	Loxodonta_africana
ENSG00000111605	CPSF6	100	100.000	ENSLAFG00000030413	CPSF6	100	100.000	Loxodonta_africana
ENSG00000111605	CPSF6	100	100.000	ENSMFAG00000045318	CPSF6	100	100.000	Macaca_fascicularis
ENSG00000111605	CPSF6	95	45.380	ENSMFAG00000001401	CPSF7	71	55.429	Macaca_fascicularis
ENSG00000111605	CPSF6	95	46.234	ENSMMUG00000015280	CPSF7	77	55.429	Macaca_mulatta
ENSG00000111605	CPSF6	100	99.830	ENSMMUG00000002921	CPSF6	100	99.830	Macaca_mulatta
ENSG00000111605	CPSF6	95	46.234	ENSMNEG00000029585	CPSF7	77	55.429	Macaca_nemestrina
ENSG00000111605	CPSF6	100	100.000	ENSMNEG00000036311	CPSF6	100	100.000	Macaca_nemestrina
ENSG00000111605	CPSF6	97	100.000	ENSMLEG00000003957	CPSF6	100	100.000	Mandrillus_leucophaeus
ENSG00000111605	CPSF6	95	45.380	ENSMLEG00000031269	CPSF7	69	55.429	Mandrillus_leucophaeus
ENSG00000111605	CPSF6	88	80.851	ENSMAMG00000010385	cpsf6	94	81.644	Mastacembelus_armatus
ENSG00000111605	CPSF6	93	85.271	ENSMZEG00005007975	cpsf6	94	81.453	Maylandia_zebra
ENSG00000111605	CPSF6	99	93.028	ENSMGAG00000010552	CPSF6	99	93.028	Meleagris_gallopavo
ENSG00000111605	CPSF6	95	45.370	ENSMGAG00000004876	CPSF7	64	61.446	Meleagris_gallopavo
ENSG00000111605	CPSF6	95	45.585	ENSMAUG00000013020	Cpsf7	71	56.000	Mesocricetus_auratus
ENSG00000111605	CPSF6	100	100.000	ENSMAUG00000013240	Cpsf6	100	100.000	Mesocricetus_auratus
ENSG00000111605	CPSF6	100	100.000	ENSMICG00000007385	-	100	100.000	Microcebus_murinus
ENSG00000111605	CPSF6	95	45.585	ENSMICG00000013788	CPSF7	71	56.000	Microcebus_murinus
ENSG00000111605	CPSF6	100	100.000	ENSMOCG00000013982	Cpsf6	100	100.000	Microtus_ochrogaster
ENSG00000111605	CPSF6	95	45.585	ENSMOCG00000000072	Cpsf7	71	56.000	Microtus_ochrogaster
ENSG00000111605	CPSF6	88	43.000	ENSMODG00000020364	CPSF7	72	56.250	Monodelphis_domestica
ENSG00000111605	CPSF6	100	99.274	ENSMODG00000007123	CPSF6	100	99.274	Monodelphis_domestica
ENSG00000111605	CPSF6	83	90.155	ENSMALG00000014908	cpsf6	79	91.525	Monopterus_albus
ENSG00000111605	CPSF6	100	100.000	MGP_CAROLIEiJ_G0015834	Cpsf6	100	100.000	Mus_caroli
ENSG00000111605	CPSF6	95	45.585	MGP_CAROLIEiJ_G0022690	Cpsf7	71	56.000	Mus_caroli
ENSG00000111605	CPSF6	100	99.660	ENSMUSG00000055531	Cpsf6	100	99.660	Mus_musculus
ENSG00000111605	CPSF6	95	45.585	ENSMUSG00000034820	Cpsf7	71	56.000	Mus_musculus
ENSG00000111605	CPSF6	95	45.585	MGP_PahariEiJ_G0014184	Cpsf7	71	56.000	Mus_pahari
ENSG00000111605	CPSF6	94	99.474	MGP_PahariEiJ_G0031253	Cpsf6	95	91.382	Mus_pahari
ENSG00000111605	CPSF6	95	45.585	MGP_SPRETEiJ_G0023604	Cpsf7	71	56.000	Mus_spretus
ENSG00000111605	CPSF6	100	99.660	MGP_SPRETEiJ_G0016657	Cpsf6	100	99.660	Mus_spretus
ENSG00000111605	CPSF6	100	95.109	ENSMPUG00000017502	CPSF6	100	95.109	Mustela_putorius_furo
ENSG00000111605	CPSF6	90	44.086	ENSMPUG00000014163	CPSF7	66	54.857	Mustela_putorius_furo
ENSG00000111605	CPSF6	99	95.628	ENSMLUG00000004172	-	100	95.628	Myotis_lucifugus
ENSG00000111605	CPSF6	87	84.946	ENSMLUG00000023960	-	81	84.324	Myotis_lucifugus
ENSG00000111605	CPSF6	88	91.489	ENSMLUG00000028728	-	92	94.907	Myotis_lucifugus
ENSG00000111605	CPSF6	95	46.444	ENSMLUG00000013278	CPSF7	77	56.000	Myotis_lucifugus
ENSG00000111605	CPSF6	95	45.585	ENSNGAG00000005031	Cpsf7	71	56.000	Nannospalax_galili
ENSG00000111605	CPSF6	100	100.000	ENSNGAG00000015901	Cpsf6	100	100.000	Nannospalax_galili
ENSG00000111605	CPSF6	84	83.333	ENSNBRG00000004089	cpsf6	94	81.644	Neolamprologus_brichardi
ENSG00000111605	CPSF6	95	45.380	ENSNLEG00000002529	CPSF7	65	55.429	Nomascus_leucogenys
ENSG00000111605	CPSF6	100	100.000	ENSNLEG00000003798	CPSF6	100	100.000	Nomascus_leucogenys
ENSG00000111605	CPSF6	100	96.599	ENSMEUG00000015041	CPSF6	99	96.599	Notamacropus_eugenii
ENSG00000111605	CPSF6	88	43.000	ENSMEUG00000002261	CPSF7	71	55.814	Notamacropus_eugenii
ENSG00000111605	CPSF6	97	99.472	ENSOPRG00000005199	CPSF6	100	99.472	Ochotona_princeps
ENSG00000111605	CPSF6	75	99.197	ENSODEG00000004418	-	90	98.800	Octodon_degus
ENSG00000111605	CPSF6	95	44.490	ENSODEG00000002610	CPSF7	71	55.618	Octodon_degus
ENSG00000111605	CPSF6	100	66.109	ENSODEG00000007109	-	66	76.101	Octodon_degus
ENSG00000111605	CPSF6	100	97.826	ENSODEG00000018399	-	100	97.826	Octodon_degus
ENSG00000111605	CPSF6	92	84.884	ENSONIG00000011702	cpsf6	95	72.982	Oreochromis_niloticus
ENSG00000111605	CPSF6	90	94.186	ENSOANG00000005944	CPSF6	57	95.266	Ornithorhynchus_anatinus
ENSG00000111605	CPSF6	99	42.059	ENSOCUG00000024726	CPSF7	71	55.429	Oryctolagus_cuniculus
ENSG00000111605	CPSF6	100	100.000	ENSOCUG00000013505	CPSF6	100	100.000	Oryctolagus_cuniculus
ENSG00000111605	CPSF6	76	35.931	ENSORLG00000006495	CPSF7	63	43.939	Oryzias_latipes
ENSG00000111605	CPSF6	94	82.857	ENSORLG00000013893	cpsf6	94	73.481	Oryzias_latipes
ENSG00000111605	CPSF6	94	82.857	ENSORLG00020016593	cpsf6	94	73.481	Oryzias_latipes_hni
ENSG00000111605	CPSF6	75	36.087	ENSORLG00020012657	CPSF7	66	41.667	Oryzias_latipes_hni
ENSG00000111605	CPSF6	76	35.931	ENSORLG00015011091	CPSF7	63	43.939	Oryzias_latipes_hsok
ENSG00000111605	CPSF6	94	82.857	ENSORLG00015015558	cpsf6	94	73.481	Oryzias_latipes_hsok
ENSG00000111605	CPSF6	94	78.137	ENSOMEG00000009425	cpsf6	81	84.896	Oryzias_melastigma
ENSG00000111605	CPSF6	72	36.797	ENSOMEG00000000539	CPSF7	78	38.235	Oryzias_melastigma
ENSG00000111605	CPSF6	95	45.585	ENSOGAG00000027958	CPSF7	66	56.000	Otolemur_garnettii
ENSG00000111605	CPSF6	97	97.373	ENSOGAG00000031988	CPSF6	100	97.373	Otolemur_garnettii
ENSG00000111605	CPSF6	97	99.475	ENSOARG00000020532	CPSF6	100	99.813	Ovis_aries
ENSG00000111605	CPSF6	75	55.385	ENSOARG00000012937	CPSF7	64	55.429	Ovis_aries
ENSG00000111605	CPSF6	97	96.853	ENSPPAG00000005301	CPSF6	98	96.853	Pan_paniscus
ENSG00000111605	CPSF6	95	45.380	ENSPPAG00000028232	CPSF7	70	55.429	Pan_paniscus
ENSG00000111605	CPSF6	100	99.830	ENSPPRG00000021620	CPSF6	100	99.830	Panthera_pardus
ENSG00000111605	CPSF6	95	46.012	ENSPPRG00000008538	CPSF7	71	56.000	Panthera_pardus
ENSG00000111605	CPSF6	91	99.813	ENSPTIG00000004079	CPSF6	100	99.813	Panthera_tigris_altaica
ENSG00000111605	CPSF6	95	45.585	ENSPTIG00000021699	CPSF7	71	56.000	Panthera_tigris_altaica
ENSG00000111605	CPSF6	95	45.380	ENSPTRG00000003742	CPSF7	71	55.429	Pan_troglodytes
ENSG00000111605	CPSF6	100	99.830	ENSPTRG00000005205	CPSF6	100	99.830	Pan_troglodytes
ENSG00000111605	CPSF6	95	45.380	ENSPANG00000006037	CPSF7	68	55.429	Papio_anubis
ENSG00000111605	CPSF6	100	100.000	ENSPANG00000011641	CPSF6	100	100.000	Papio_anubis
ENSG00000111605	CPSF6	88	84.211	ENSPKIG00000022613	CPSF6	94	81.453	Paramormyrops_kingsleyae
ENSG00000111605	CPSF6	95	82.375	ENSPKIG00000003081	-	94	82.726	Paramormyrops_kingsleyae
ENSG00000111605	CPSF6	85	33.981	ENSPKIG00000018054	CPSF7	72	47.205	Paramormyrops_kingsleyae
ENSG00000111605	CPSF6	58	40.404	ENSPSIG00000015092	-	92	43.537	Pelodiscus_sinensis
ENSG00000111605	CPSF6	56	94.512	ENSPSIG00000016360	CPSF6	76	94.512	Pelodiscus_sinensis
ENSG00000111605	CPSF6	95	46.444	ENSPEMG00000012648	Cpsf7	77	56.000	Peromyscus_maniculatus_bairdii
ENSG00000111605	CPSF6	97	99.824	ENSPEMG00000007973	Cpsf6	100	99.824	Peromyscus_maniculatus_bairdii
ENSG00000111605	CPSF6	88	36.842	ENSPMAG00000008077	-	68	51.323	Petromyzon_marinus
ENSG00000111605	CPSF6	64	60.000	ENSPMAG00000000657	cpsf6	57	84.615	Petromyzon_marinus
ENSG00000111605	CPSF6	100	99.320	ENSPCIG00000019063	CPSF6	100	99.320	Phascolarctos_cinereus
ENSG00000111605	CPSF6	95	42.094	ENSPCIG00000002551	CPSF7	95	55.191	Phascolarctos_cinereus
ENSG00000111605	CPSF6	88	79.787	ENSPFOG00000006990	cpsf6	53	81.853	Poecilia_formosa
ENSG00000111605	CPSF6	94	79.350	ENSPLAG00000005715	cpsf6	94	81.369	Poecilia_latipinna
ENSG00000111605	CPSF6	94	79.350	ENSPMEG00000001353	cpsf6	94	81.369	Poecilia_mexicana
ENSG00000111605	CPSF6	88	79.787	ENSPREG00000004417	cpsf6	52	78.873	Poecilia_reticulata
ENSG00000111605	CPSF6	95	45.380	ENSPPYG00000003188	CPSF7	71	55.429	Pongo_abelii
ENSG00000111605	CPSF6	100	99.819	ENSPPYG00000004756	CPSF6	100	99.819	Pongo_abelii
ENSG00000111605	CPSF6	100	100.000	ENSPCAG00000011574	CPSF6	100	100.000	Procavia_capensis
ENSG00000111605	CPSF6	95	45.585	ENSPCOG00000011976	CPSF7	71	56.000	Propithecus_coquereli
ENSG00000111605	CPSF6	100	99.660	ENSPCOG00000024384	CPSF6	100	99.660	Propithecus_coquereli
ENSG00000111605	CPSF6	95	45.380	ENSPVAG00000010675	CPSF7	71	56.000	Pteropus_vampyrus
ENSG00000111605	CPSF6	100	99.490	ENSPVAG00000015753	CPSF6	100	99.490	Pteropus_vampyrus
ENSG00000111605	CPSF6	93	85.271	ENSPNYG00000020315	cpsf6	77	85.441	Pundamilia_nyererei
ENSG00000111605	CPSF6	88	78.723	ENSPNAG00000024098	CPSF6	82	83.420	Pygocentrus_nattereri
ENSG00000111605	CPSF6	54	46.497	ENSPNAG00000015073	CPSF7	69	46.061	Pygocentrus_nattereri
ENSG00000111605	CPSF6	100	99.819	ENSRNOG00000005927	Cpsf6	100	99.819	Rattus_norvegicus
ENSG00000111605	CPSF6	87	54.872	ENSRNOG00000020668	Cpsf7	77	55.814	Rattus_norvegicus
ENSG00000111605	CPSF6	100	99.660	ENSRBIG00000042827	CPSF6	100	99.660	Rhinopithecus_bieti
ENSG00000111605	CPSF6	95	46.234	ENSRBIG00000031429	CPSF7	95	54.857	Rhinopithecus_bieti
ENSG00000111605	CPSF6	95	45.380	ENSRROG00000045009	CPSF7	71	55.429	Rhinopithecus_roxellana
ENSG00000111605	CPSF6	100	99.830	ENSRROG00000042758	CPSF6	100	99.830	Rhinopithecus_roxellana
ENSG00000111605	CPSF6	97	99.476	ENSSBOG00000010652	CPSF6	100	100.000	Saimiri_boliviensis_boliviensis
ENSG00000111605	CPSF6	95	45.380	ENSSBOG00000018431	CPSF7	71	55.429	Saimiri_boliviensis_boliviensis
ENSG00000111605	CPSF6	62	54.822	ENSSHAG00000011964	CPSF7	69	56.395	Sarcophilus_harrisii
ENSG00000111605	CPSF6	70	90.667	ENSSHAG00000006635	CPSF6	94	95.059	Sarcophilus_harrisii
ENSG00000111605	CPSF6	95	79.732	ENSSFOG00015001688	CPSF6	82	82.184	Scleropages_formosus
ENSG00000111605	CPSF6	95	83.397	ENSSFOG00015015803	CPSF6	94	80.880	Scleropages_formosus
ENSG00000111605	CPSF6	98	38.525	ENSSFOG00015010288	cpsf7	78	40.000	Scleropages_formosus
ENSG00000111605	CPSF6	88	80.851	ENSSMAG00000000471	cpsf6	92	83.525	Scophthalmus_maximus
ENSG00000111605	CPSF6	88	81.915	ENSSDUG00000005024	cpsf6	94	82.409	Seriola_dumerili
ENSG00000111605	CPSF6	88	81.915	ENSSLDG00000009042	cpsf6	94	82.409	Seriola_lalandi_dorsalis
ENSG00000111605	CPSF6	99	98.947	ENSSARG00000006743	CPSF6	95	92.101	Sorex_araneus
ENSG00000111605	CPSF6	94	92.559	ENSSPUG00000001238	CPSF6	100	92.955	Sphenodon_punctatus
ENSG00000111605	CPSF6	95	47.122	ENSSPUG00000019344	CPSF7	73	56.977	Sphenodon_punctatus
ENSG00000111605	CPSF6	88	80.851	ENSSPAG00000013906	cpsf6	94	82.792	Stegastes_partitus
ENSG00000111605	CPSF6	95	45.585	ENSSSCG00000013083	CPSF7	84	55.429	Sus_scrofa
ENSG00000111605	CPSF6	100	100.000	ENSSSCG00000038031	CPSF6	100	100.000	Sus_scrofa
ENSG00000111605	CPSF6	88	40.000	ENSTGUG00000006513	CPSF7	71	56.322	Taeniopygia_guttata
ENSG00000111605	CPSF6	88	77.660	ENSTRUG00000016461	cpsf6	94	79.350	Takifugu_rubripes
ENSG00000111605	CPSF6	88	75.532	ENSTNIG00000007576	cpsf6	94	79.541	Tetraodon_nigroviridis
ENSG00000111605	CPSF6	90	44.301	ENSTTRG00000011085	CPSF7	70	56.000	Tursiops_truncatus
ENSG00000111605	CPSF6	91	100.000	ENSUAMG00000023492	CPSF6	100	100.000	Ursus_americanus
ENSG00000111605	CPSF6	95	45.585	ENSUAMG00000017809	CPSF7	71	56.000	Ursus_americanus
ENSG00000111605	CPSF6	91	100.000	ENSUMAG00000020779	CPSF6	100	100.000	Ursus_maritimus
ENSG00000111605	CPSF6	95	46.444	ENSUMAG00000011825	CPSF7	77	56.000	Ursus_maritimus
ENSG00000111605	CPSF6	97	100.000	ENSVPAG00000008469	CPSF6	100	100.000	Vicugna_pacos
ENSG00000111605	CPSF6	91	100.000	ENSVVUG00000010156	-	100	100.000	Vulpes_vulpes
ENSG00000111605	CPSF6	95	45.585	ENSVVUG00000004939	CPSF7	84	55.429	Vulpes_vulpes
ENSG00000111605	CPSF6	97	41.468	ENSXETG00000006715	cpsf7	85	34.672	Xenopus_tropicalis
ENSG00000111605	CPSF6	88	79.787	ENSXCOG00000013423	cpsf6	52	78.873	Xiphophorus_couchianus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0003723	RNA binding	22658674.22681889.	HDA	Function
GO:0003723	RNA binding	15169763.	IDA	Function
GO:0003729	mRNA binding	21295486.	IDA	Function
GO:0005515	protein binding	14561889.15169763.16189514.19447967.19864460.21295486.22960638.25416956.29276085.29507755.	IPI	Function
GO:0005634	nucleus	19864460.20695905.	IDA	Component
GO:0005654	nucleoplasm	17267687.	IDA	Component
GO:0005726	perichromatin fibrils	17267687.	IDA	Component
GO:0005737	cytoplasm	19864460.	IDA	Component
GO:0005847	mRNA cleavage and polyadenylation specificity factor complex	23187700.	IDA	Component
GO:0005849	mRNA cleavage factor complex	9659921.20695905.29276085.	IDA	Component
GO:0006397	mRNA processing	14690600.	IDA	Process
GO:0016020	membrane	19946888.	HDA	Component
GO:0016607	nuclear speck	17267687.	IDA	Component
GO:0035061	interchromatin granule	17267687.	IDA	Component
GO:0042382	paraspeckles	9659921.17267687.	IDA	Component
GO:0043023	ribosomal large subunit binding	19864460.	IDA	Function
GO:0046833	positive regulation of RNA export from nucleus	19864460.	IMP	Process
GO:0051262	protein tetramerization	20695905.	IDA	Process
GO:0051290	protein heterotetramerization	23187700.	IDA	Process
GO:0098789	pre-mRNA cleavage required for polyadenylation	20695905.	IMP	Process
GO:0110104	mRNA alternative polyadenylation	20695905.23187700.29276085.	IMP	Process
GO:1990120	messenger ribonucleoprotein complex assembly	29276085.	IDA	Process
GO:1990448	exon-exon junction complex binding	19864460.	IDA	Function
GO:1990904	ribonucleoprotein complex	18809582.	IDA	Component