EuRBPDB

Description

Ensembl ID: ENSG00000111615 (Gene tree)
Gene ID: 11103
Gene Symbol: KRR1
Alias: RIP-1|HRB2
Full Name: KRR1 small subunit processome component homolog
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Minus strand
Length: 20,778 bases
Position: chr12:75,490,861-75,511,638
Accession: 5176
RBP type: non-canonical RBP
Summary: (KRR1 Small Subunit Processome Component Homolog) is a Protein Coding gene. Among its related pathways are rRNA processing in the nucleus and cytosol and Gene Expression. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and RNA binding.

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
22681889	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts	4SURIC & HEK293	2012 May	Baltz AG	DOI: 10.1016/j.molcel.2012.05.021
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
29431736	Capturing the interactome of newly transcribed RNA	PolyT-RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	RIC & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
22658674	Insights into RNA biology from an atlas of mammalian mRNA-binding proteins	RIC & Hela	2012 May 31	Castello A	DOI: 10.1016/j.cell.2012.04.031
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30352994	Discovery of RNA-binding proteins and characterization of their dynamic responses by enhanced RNA interactome capture	RIC & Jurkat	2018 Oct 23	Perez-Perri JI	DOI:10.1038/s41467-018-06557-8

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
19159951	Malignant fibrous histiocytoma--pleomorphic sarcoma, NOS gene expression, histology, and clinical course. A pilot study.	Langenbecks Arch Surg	2010 Mar	Daigeler A	doi: 10.1007/s00423-009-0465-0

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000550898	KRR1-204	694	-	-	- (aa)	-	-
ENST00000551070	KRR1-205	673	-	-	- (aa)	-	-
ENST00000550023	KRR1-203	855	-	-	- (aa)	-	-
ENST00000229214	KRR1-201	10118	-	ENSP00000229214	381 (aa)	-	Q13601
ENST00000438169	KRR1-202	975	-	ENSP00000411740	324 (aa)	-	Q13601

Gene Model

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000111615	monocyte chemoattractant protein 1 (66-77)	5.0280000E-005	-
ENSG00000111615	Polycystic Ovary Syndrome	2E-8	26416764
ENSG00000111615	Rest	8E-6	27126917

Protein-Protein Interaction (PPI)

* RBP PPI network refers to all genes directly bind to RBP

Orthologs identified by RBPome

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000111615	KRR1	100	92.126	ENSMUSG00000063334	Krr1	98	92.513	Mus_musculus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0003723	RNA binding	22658674.22681889.	HDA	Function
GO:0005515	protein binding	19590578.	IPI	Function
GO:0005634	nucleus	-	IDA	Component
GO:0005654	nucleoplasm	-	TAS	Component
GO:0005730	nucleolus	21873635.	IBA	Component
GO:0005730	nucleolus	-	IDA	Component
GO:0005737	cytoplasm	-	IEA	Component
GO:0006364	rRNA processing	-	TAS	Process
GO:0016020	membrane	19946888.	HDA	Component
GO:0032040	small-subunit processome	21873635.	IBA	Component
GO:0045171	intercellular bridge	-	IDA	Component