EuRBPDB

Description

RBDs

RBPome

Expression

Transcripts

Gene Model

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000111639 (Gene tree)
Gene ID: 51258
Gene Symbol: MRPL51
Alias: CDA09|HSPC241|bMRP64|MRP64
Full Name: mitochondrial ribosomal protein L51
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Minus strand
Length: 1,956 bases
Position: chr12:6,491,886-6,493,841
Accession: 14044
RBP type: canonical RBP
Summary: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Pseudogenes corresponding to this gene are found on chromosomes 4p and 21q. [provided by RefSeq, Jul 2008]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000229238	MRP-L51	PF10244.9	1.9e-35	1	1
ENSP00000477598	MRP-L51	PF10244.9	8.3e-29	1	1
ENSP00000478132	MRP-L51	PF10244.9	8.3e-29	1	1
ENSP00000480329	MRP-L51	PF10244.9	8.3e-29	1	1
ENSP00000482353	MRP-L51	PF10244.9	8.3e-29	1	1
ENSP00000478326	MRP-L51	PF10244.9	1.5e-28	1	1
ENSP00000471687	MRP-L51	PF10244.9	1.5e-05	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
27453046	Comprehensive Identification of RNA-Binding Domains in Human Cells	RIC & Hela	2016 Aug 18	Castello A	DOI: 10.1016/j.molcel.2016.06.029

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000540949	MRPL51-204	343	-	ENSP00000478326	73 (aa)	-	A0A087WU28
ENST00000538814	MRPL51-203	501	-	ENSP00000478132	76 (aa)	-	A0A0B4J2C1
ENST00000543703	MRPL51-206	441	-	ENSP00000471687	32 (aa)	-	M0R176
ENST00000543164	MRPL51-205	814	-	ENSP00000482353	76 (aa)	-	A0A0B4J2C1
ENST00000543959	MRPL51-207	472	-	ENSP00000477598	76 (aa)	-	A0A0B4J2C1
ENST00000537701	MRPL51-202	601	-	ENSP00000480329	76 (aa)	-	A0A0B4J2C1
ENST00000229238	MRPL51-201	1234	-	ENSP00000229238	128 (aa)	-	Q4U2R6

Gene Model

Click here to download ENSG00000111639's gene model file

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000111639's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000111639	MRPL51	100	71.233	ENSAPOG00000010274	mrpl51	70	68.478	Acanthochromis_polyacanthus
ENSG00000111639	MRPL51	100	90.411	ENSAMEG00000014426	MRPL51	100	85.938	Ailuropoda_melanoleuca
ENSG00000111639	MRPL51	100	67.123	ENSACIG00000012151	mrpl51	99	54.545	Amphilophus_citrinellus
ENSG00000111639	MRPL51	100	69.863	ENSAOCG00000009160	mrpl51	70	67.391	Amphiprion_ocellaris
ENSG00000111639	MRPL51	100	69.863	ENSAPEG00000011818	mrpl51	70	67.391	Amphiprion_percula
ENSG00000111639	MRPL51	100	68.493	ENSATEG00000021472	mrpl51	58	59.813	Anabas_testudineus
ENSG00000111639	MRPL51	100	78.082	ENSACAG00000006677	MRPL51	57	77.778	Anolis_carolinensis
ENSG00000111639	MRPL51	100	94.521	ENSANAG00000021671	MRPL51	100	92.969	Aotus_nancymaae
ENSG00000111639	MRPL51	100	93.151	ENSANAG00000022989	-	98	80.159	Aotus_nancymaae
ENSG00000111639	MRPL51	100	68.493	ENSACLG00000024277	mrpl51	81	62.037	Astatotilapia_calliptera
ENSG00000111639	MRPL51	100	65.625	ENSAMXG00000032697	mrpl51	68	56.410	Astyanax_mexicanus
ENSG00000111639	MRPL51	100	87.671	ENSBTAG00000014729	MRPL51	100	82.031	Bos_taurus
ENSG00000111639	MRPL51	91	36.364	WBGene00011740	mrpl-51	53	34.286	Caenorhabditis_elegans
ENSG00000111639	MRPL51	100	95.890	ENSCJAG00000046530	MRPL51	100	92.188	Callithrix_jacchus
ENSG00000111639	MRPL51	100	86.301	ENSCAFG00000030812	MRPL51	100	80.469	Canis_familiaris
ENSG00000111639	MRPL51	100	86.301	ENSCAFG00020002857	MRPL51	100	80.469	Canis_lupus_dingo
ENSG00000111639	MRPL51	100	87.671	ENSCHIG00000011385	MRPL51	100	82.031	Capra_hircus
ENSG00000111639	MRPL51	100	87.671	ENSCPOG00000008478	MRPL51	100	81.250	Cavia_porcellus
ENSG00000111639	MRPL51	100	94.521	ENSCCAG00000030846	MRPL51	100	92.969	Cebus_capucinus
ENSG00000111639	MRPL51	100	97.368	ENSCATG00000035810	MRPL51	100	96.875	Cercocebus_atys
ENSG00000111639	MRPL51	100	90.625	ENSCLAG00000011881	MRPL51	100	84.375	Chinchilla_lanigera
ENSG00000111639	MRPL51	100	98.630	ENSCSAG00000010565	MRPL51	100	96.875	Chlorocebus_sabaeus
ENSG00000111639	MRPL51	100	91.781	ENSCHOG00000001069	MRPL51	100	84.375	Choloepus_hoffmanni
ENSG00000111639	MRPL51	100	95.890	ENSCANG00000033038	MRPL51	100	95.312	Colobus_angolensis_palliatus
ENSG00000111639	MRPL51	100	87.500	ENSCGRG00001004726	-	100	85.526	Cricetulus_griseus_chok1gshd
ENSG00000111639	MRPL51	100	93.750	ENSCGRG00001010566	-	100	80.620	Cricetulus_griseus_chok1gshd
ENSG00000111639	MRPL51	100	93.750	ENSCGRG00000016012	Mrpl51	100	79.845	Cricetulus_griseus_crigri
ENSG00000111639	MRPL51	100	69.863	ENSCSEG00000019976	mrpl51	82	65.138	Cynoglossus_semilaevis
ENSG00000111639	MRPL51	100	71.233	ENSCVAG00000001138	mrpl51	84	63.063	Cyprinodon_variegatus
ENSG00000111639	MRPL51	100	69.863	ENSDARG00000041340	mrpl51	95	58.824	Danio_rerio
ENSG00000111639	MRPL51	100	91.781	ENSDNOG00000001127	MRPL51	100	85.156	Dasypus_novemcinctus
ENSG00000111639	MRPL51	100	89.041	ENSDORG00000028160	Mrpl51	100	88.158	Dipodomys_ordii
ENSG00000111639	MRPL51	97	44.737	FBgn0032053	mRpL51	57	42.424	Drosophila_melanogaster
ENSG00000111639	MRPL51	100	68.750	ENSETEG00000013743	-	100	68.750	Echinops_telfairi
ENSG00000111639	MRPL51	100	68.421	ENSEBUG00000011397	MRPL51	71	68.478	Eptatretus_burgeri
ENSG00000111639	MRPL51	100	93.151	ENSEASG00005016160	MRPL51	100	85.156	Equus_asinus_asinus
ENSG00000111639	MRPL51	100	93.151	ENSECAG00000017430	MRPL51	100	85.156	Equus_caballus
ENSG00000111639	MRPL51	100	90.411	ENSEEUG00000003243	MRPL51	100	84.375	Erinaceus_europaeus
ENSG00000111639	MRPL51	100	68.493	ENSELUG00000017748	mrpl51	93	59.504	Esox_lucius
ENSG00000111639	MRPL51	100	90.411	ENSFCAG00000043270	MRPL51	100	83.594	Felis_catus
ENSG00000111639	MRPL51	100	75.342	ENSFALG00000004836	MRPL51	92	59.398	Ficedula_albicollis
ENSG00000111639	MRPL51	100	93.151	ENSFDAG00000018319	MRPL51	100	83.594	Fukomys_damarensis
ENSG00000111639	MRPL51	100	69.863	ENSFHEG00000012964	mrpl51	97	55.118	Fundulus_heteroclitus
ENSG00000111639	MRPL51	100	69.863	ENSGMOG00000010300	mrpl51	92	67.391	Gadus_morhua
ENSG00000111639	MRPL51	100	75.342	ENSGALG00000014435	MRPL51	85	63.415	Gallus_gallus
ENSG00000111639	MRPL51	100	69.863	ENSGAFG00000014285	mrpl51	83	63.063	Gambusia_affinis
ENSG00000111639	MRPL51	100	67.123	ENSGACG00000010193	mrpl51	82	59.633	Gasterosteus_aculeatus
ENSG00000111639	MRPL51	100	72.603	ENSGAGG00000015360	MRPL51	84	65.138	Gopherus_agassizii
ENSG00000111639	MRPL51	100	100.000	ENSGGOG00000016199	MRPL51	100	100.000	Gorilla_gorilla
ENSG00000111639	MRPL51	100	68.493	ENSHBUG00000015507	mrpl51	81	62.037	Haplochromis_burtoni
ENSG00000111639	MRPL51	100	90.411	ENSHGLG00000001887	MRPL51	100	82.812	Heterocephalus_glaber_female
ENSG00000111639	MRPL51	100	90.411	ENSHGLG00100010169	MRPL51	100	82.812	Heterocephalus_glaber_male
ENSG00000111639	MRPL51	100	65.789	ENSHCOG00000017637	mrpl51	82	61.468	Hippocampus_comes
ENSG00000111639	MRPL51	100	65.789	ENSIPUG00000000149	mrpl51	97	54.331	Ictalurus_punctatus
ENSG00000111639	MRPL51	100	90.411	ENSSTOG00000007484	MRPL51	100	85.271	Ictidomys_tridecemlineatus
ENSG00000111639	MRPL51	100	89.041	ENSJJAG00000018962	Mrpl51	100	76.119	Jaculus_jaculus
ENSG00000111639	MRPL51	100	68.493	ENSKMAG00000007684	mrpl51	69	70.330	Kryptolebias_marmoratus
ENSG00000111639	MRPL51	100	67.123	ENSLBEG00000006744	mrpl51	97	54.331	Labrus_bergylta
ENSG00000111639	MRPL51	100	78.125	ENSLACG00000002154	MRPL51	90	76.087	Latimeria_chalumnae
ENSG00000111639	MRPL51	100	72.603	ENSLOCG00000007108	mrpl51	97	58.730	Lepisosteus_oculatus
ENSG00000111639	MRPL51	100	91.781	ENSLAFG00000002106	MRPL51	100	85.938	Loxodonta_africana
ENSG00000111639	MRPL51	100	95.890	ENSMFAG00000041444	MRPL51	100	95.312	Macaca_fascicularis
ENSG00000111639	MRPL51	100	95.890	ENSMNEG00000032063	MRPL51	100	95.312	Macaca_nemestrina
ENSG00000111639	MRPL51	100	97.368	ENSMLEG00000033346	MRPL51	100	96.875	Mandrillus_leucophaeus
ENSG00000111639	MRPL51	100	67.123	ENSMAMG00000002286	mrpl51	70	66.304	Mastacembelus_armatus
ENSG00000111639	MRPL51	100	68.493	ENSMZEG00005017651	mrpl51	81	62.037	Maylandia_zebra
ENSG00000111639	MRPL51	100	75.342	ENSMGAG00000014092	MRPL51	99	75.000	Meleagris_gallopavo
ENSG00000111639	MRPL51	100	89.041	ENSMAUG00000010740	Mrpl51	100	79.688	Mesocricetus_auratus
ENSG00000111639	MRPL51	100	90.411	ENSMICG00000027914	MRPL51	100	84.375	Microcebus_murinus
ENSG00000111639	MRPL51	100	93.750	ENSMOCG00000013685	Mrpl51	100	83.594	Microtus_ochrogaster
ENSG00000111639	MRPL51	100	65.789	ENSMMOG00000016030	mrpl51	97	53.846	Mola_mola
ENSG00000111639	MRPL51	100	86.301	ENSMODG00000018063	MRPL51	100	74.219	Monodelphis_domestica
ENSG00000111639	MRPL51	100	69.863	ENSMALG00000022486	mrpl51	81	63.889	Monopterus_albus
ENSG00000111639	MRPL51	100	84.932	ENSMUSG00000030335	Mrpl51	100	82.031	Mus_musculus
ENSG00000111639	MRPL51	100	86.301	MGP_PahariEiJ_G0022634	Mrpl51	100	80.469	Mus_pahari
ENSG00000111639	MRPL51	100	84.932	MGP_SPRETEiJ_G0029916	Mrpl51	100	81.250	Mus_spretus
ENSG00000111639	MRPL51	100	87.671	ENSMPUG00000016904	MRPL51	100	82.812	Mustela_putorius_furo
ENSG00000111639	MRPL51	100	89.041	ENSNGAG00000022754	Mrpl51	100	81.250	Nannospalax_galili
ENSG00000111639	MRPL51	100	67.123	ENSNBRG00000000391	mrpl51	81	61.111	Neolamprologus_brichardi
ENSG00000111639	MRPL51	96	84.286	ENSNLEG00000033479	-	100	77.869	Nomascus_leucogenys
ENSG00000111639	MRPL51	100	98.684	ENSNLEG00000033120	MRPL51	100	98.438	Nomascus_leucogenys
ENSG00000111639	MRPL51	100	84.932	ENSMEUG00000015252	MRPL51	100	75.000	Notamacropus_eugenii
ENSG00000111639	MRPL51	100	86.301	ENSODEG00000004435	MRPL51	100	81.250	Octodon_degus
ENSG00000111639	MRPL51	100	68.493	ENSONIG00000012928	mrpl51	81	62.037	Oreochromis_niloticus
ENSG00000111639	MRPL51	100	69.863	ENSOANG00000003012	-	87	65.138	Ornithorhynchus_anatinus
ENSG00000111639	MRPL51	100	93.151	ENSOCUG00000008170	MRPL51	100	85.156	Oryctolagus_cuniculus
ENSG00000111639	MRPL51	100	67.123	ENSORLG00000026054	MRPL51	92	55.469	Oryzias_latipes
ENSG00000111639	MRPL51	100	67.123	ENSORLG00020005100	mrpl51	82	60.000	Oryzias_latipes_hni
ENSG00000111639	MRPL51	100	68.493	ENSORLG00015010985	mrpl51	92	56.250	Oryzias_latipes_hsok
ENSG00000111639	MRPL51	100	68.493	ENSOMEG00000013053	mrpl51	82	61.818	Oryzias_melastigma
ENSG00000111639	MRPL51	100	94.521	ENSOGAG00000031255	MRPL51	100	85.938	Otolemur_garnettii
ENSG00000111639	MRPL51	100	87.671	ENSOARG00000008170	MRPL51	100	82.031	Ovis_aries
ENSG00000111639	MRPL51	100	100.000	ENSPPAG00000040001	MRPL51	100	100.000	Pan_paniscus
ENSG00000111639	MRPL51	100	90.411	ENSPPRG00000000742	MRPL51	100	82.812	Panthera_pardus
ENSG00000111639	MRPL51	100	90.411	ENSPTIG00000016877	MRPL51	100	82.812	Panthera_tigris_altaica
ENSG00000111639	MRPL51	100	100.000	ENSPTRG00000004575	MRPL51	100	99.219	Pan_troglodytes
ENSG00000111639	MRPL51	100	97.368	ENSPANG00000030836	MRPL51	100	96.875	Papio_anubis
ENSG00000111639	MRPL51	99	66.667	ENSPKIG00000007188	mrpl51	98	53.906	Paramormyrops_kingsleyae
ENSG00000111639	MRPL51	100	73.973	ENSPSIG00000016487	MRPL51	65	75.000	Pelodiscus_sinensis
ENSG00000111639	MRPL51	100	65.789	ENSPMGG00000004465	mrpl51	84	59.091	Periophthalmus_magnuspinnatus
ENSG00000111639	MRPL51	100	87.671	ENSPEMG00000008667	Mrpl51	99	80.833	Peromyscus_maniculatus_bairdii
ENSG00000111639	MRPL51	100	72.603	ENSPMAG00000002833	MRPL51	92	63.248	Petromyzon_marinus
ENSG00000111639	MRPL51	100	86.301	ENSPCIG00000013024	MRPL51	100	85.526	Phascolarctos_cinereus
ENSG00000111639	MRPL51	100	69.863	ENSPFOG00000013680	mrpl51	87	58.594	Poecilia_formosa
ENSG00000111639	MRPL51	100	69.863	ENSPLAG00000000112	mrpl51	87	58.594	Poecilia_latipinna
ENSG00000111639	MRPL51	100	69.863	ENSPMEG00000016529	mrpl51	87	58.594	Poecilia_mexicana
ENSG00000111639	MRPL51	100	68.493	ENSPREG00000011034	mrpl51	99	57.812	Poecilia_reticulata
ENSG00000111639	MRPL51	100	100.000	ENSPPYG00000025846	MRPL51	100	99.219	Pongo_abelii
ENSG00000111639	MRPL51	100	94.521	ENSPCOG00000024470	-	100	86.719	Propithecus_coquereli
ENSG00000111639	MRPL51	100	91.781	ENSPCOG00000024091	-	99	84.906	Propithecus_coquereli
ENSG00000111639	MRPL51	100	91.781	ENSPVAG00000012566	MRPL51	100	86.719	Pteropus_vampyrus
ENSG00000111639	MRPL51	100	68.493	ENSPNYG00000023096	mrpl51	81	62.037	Pundamilia_nyererei
ENSG00000111639	MRPL51	100	68.493	ENSPNAG00000017837	mrpl51	87	60.550	Pygocentrus_nattereri
ENSG00000111639	MRPL51	100	86.301	ENSRNOG00000019165	Mrpl51	100	78.125	Rattus_norvegicus
ENSG00000111639	MRPL51	100	95.890	ENSRBIG00000029250	-	100	94.531	Rhinopithecus_bieti
ENSG00000111639	MRPL51	100	95.890	ENSRBIG00000029992	-	100	94.531	Rhinopithecus_bieti
ENSG00000111639	MRPL51	100	95.890	ENSRROG00000020883	-	100	94.531	Rhinopithecus_roxellana
ENSG00000111639	MRPL51	100	95.890	ENSRROG00000033245	-	100	94.531	Rhinopithecus_roxellana
ENSG00000111639	MRPL51	100	94.521	ENSSBOG00000028416	MRPL51	100	92.969	Saimiri_boliviensis_boliviensis
ENSG00000111639	MRPL51	100	82.192	ENSSHAG00000014803	MRPL51	100	71.094	Sarcophilus_harrisii
ENSG00000111639	MRPL51	100	71.875	ENSSFOG00015002742	mrpl51	84	64.545	Scleropages_formosus
ENSG00000111639	MRPL51	100	69.863	ENSSMAG00000011479	mrpl51	70	67.391	Scophthalmus_maximus
ENSG00000111639	MRPL51	100	68.493	ENSSDUG00000011778	mrpl51	65	55.469	Seriola_dumerili
ENSG00000111639	MRPL51	100	68.493	ENSSLDG00000023639	mrpl51	82	59.633	Seriola_lalandi_dorsalis
ENSG00000111639	MRPL51	100	75.342	ENSSPUG00000015396	MRPL51	63	75.556	Sphenodon_punctatus
ENSG00000111639	MRPL51	100	69.863	ENSSPAG00000018354	mrpl51	72	67.391	Stegastes_partitus
ENSG00000111639	MRPL51	100	91.781	ENSSSCG00000039662	MRPL51	100	82.031	Sus_scrofa
ENSG00000111639	MRPL51	100	78.125	ENSTGUG00000013340	MRPL51	74	66.372	Taeniopygia_guttata
ENSG00000111639	MRPL51	100	67.123	ENSTRUG00000025696	mrpl51	98	55.385	Takifugu_rubripes
ENSG00000111639	MRPL51	100	69.863	ENSTNIG00000008038	mrpl51	82	62.385	Tetraodon_nigroviridis
ENSG00000111639	MRPL51	100	91.781	ENSTBEG00000000936	MRPL51	100	85.156	Tupaia_belangeri
ENSG00000111639	MRPL51	100	89.041	ENSTTRG00000016086	MRPL51	100	82.812	Tursiops_truncatus
ENSG00000111639	MRPL51	100	90.411	ENSUAMG00000022539	MRPL51	100	85.938	Ursus_americanus
ENSG00000111639	MRPL51	100	90.411	ENSUMAG00000007393	MRPL51	100	85.938	Ursus_maritimus
ENSG00000111639	MRPL51	100	90.411	ENSVPAG00000008827	MRPL51	100	85.156	Vicugna_pacos
ENSG00000111639	MRPL51	100	86.301	ENSVVUG00000012022	MRPL51	100	79.688	Vulpes_vulpes
ENSG00000111639	MRPL51	100	75.342	ENSXETG00000022612	mrpl51	86	67.890	Xenopus_tropicalis
ENSG00000111639	MRPL51	100	68.493	ENSXMAG00000011410	mrpl51	73	69.231	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0003735	structural constituent of ribosome	21873635.	IBA	Function
GO:0003735	structural constituent of ribosome	11402041.	ISS	Function
GO:0005515	protein binding	20601428.	IPI	Function
GO:0005739	mitochondrion	28892042.	IDA	Component
GO:0005743	mitochondrial inner membrane	-	TAS	Component
GO:0005761	mitochondrial ribosome	20601428.	IDA	Component
GO:0005762	mitochondrial large ribosomal subunit	21873635.	IBA	Component
GO:0005762	mitochondrial large ribosomal subunit	25278503.28892042.	IDA	Component
GO:0005762	mitochondrial large ribosomal subunit	-	ISS	Component
GO:0006412	translation	21873635.	IBA	Process
GO:0006412	translation	-	ISS	Process
GO:0032543	mitochondrial translation	11402041.	ISS	Process
GO:0070125	mitochondrial translational elongation	-	TAS	Process
GO:0070126	mitochondrial translational termination	-	TAS	Process