EuRBPDB

Description

RBDs

Expression

Transcripts

Gene Model

Pathways

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000111737 (Gene tree)
Gene ID: 11021
Gene Symbol: RAB35
Alias: H-ray
Full Name: RAB35, member RAS oncogene family
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Minus strand
Length: 22,409 bases
Position: chr12:120,095,094-120,117,502
Accession: 9774
RBP type: canonical RBP
Summary: RAB35 (RAB35, Member RAS Oncogene Family) is a Protein Coding gene. Diseases associated with RAB35 include Hypotrichosis 3 and Charcot-Marie-Tooth Disease, Axonal, Type 2L. Among its related pathways are RAB geranylgeranylation and Vesicle-mediated transport. Gene Ontology (GO) annotations related to this gene include GTP binding and GDP binding. An important paralog of this gene is RAB1A.

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000441883	MMR_HSR1	PF01926.23	2.3e-05	1	1
ENSP00000229340	MMR_HSR1	PF01926.23	2.3e-05	1	1
ENSP00000443994	MMR_HSR1	PF01926.23	0.00011	1	1

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000534951	RAB35-202	939	-	ENSP00000441883	152 (aa)	-	Q15286
ENST00000229340	RAB35-201	2945	XM_011537779	ENSP00000229340	201 (aa)	XP_011536081	Q15286
ENST00000538903	RAB35-203	643	-	ENSP00000443994	185 (aa)	-	F5H157
ENST00000544304	RAB35-206	2449	-	ENSP00000442555	147 (aa)	-	F5H7F8
ENST00000540803	RAB35-204	551	-	-	- (aa)	-	-
ENST00000543364	RAB35-205	578	-	-	- (aa)	-	-

Gene Model

Click here to download ENSG00000111737's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa04144	Endocytosis	KEGG

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000111737	Aspartate Aminotransferases	4E-6	23251661

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000111737	rs2239200	12	120100847	T	Heel bone mineral density	30598549	[0.013-0.026] unit increase	0.0198994	EFO_0009270

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000111737's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000111737	RAB35	100	94.030	ENSAPOG00000007363	rab35b	100	94.030	Acanthochromis_polyacanthus
ENSG00000111737	RAB35	100	94.030	ENSAOCG00000005934	rab35b	100	94.030	Amphiprion_ocellaris
ENSG00000111737	RAB35	100	94.030	ENSAPEG00000001130	rab35b	100	94.030	Amphiprion_percula
ENSG00000111737	RAB35	100	93.532	ENSATEG00000013281	rab35b	100	93.532	Anabas_testudineus
ENSG00000111737	RAB35	100	99.502	ENSACAG00000003643	RAB35	100	99.502	Anolis_carolinensis
ENSG00000111737	RAB35	100	100.000	ENSANAG00000036954	RAB35	100	100.000	Aotus_nancymaae
ENSG00000111737	RAB35	100	93.532	ENSAMXG00000039865	rab35b	100	93.532	Astyanax_mexicanus
ENSG00000111737	RAB35	100	90.547	ENSAMXG00000040604	-	100	90.547	Astyanax_mexicanus
ENSG00000111737	RAB35	100	100.000	ENSBTAG00000022044	RAB35	100	100.000	Bos_taurus
ENSG00000111737	RAB35	100	100.000	ENSCJAG00000008955	RAB35	100	100.000	Callithrix_jacchus
ENSG00000111737	RAB35	100	100.000	ENSCAFG00020018913	RAB35	100	100.000	Canis_lupus_dingo
ENSG00000111737	RAB35	100	100.000	ENSCCAG00000031720	RAB35	100	100.000	Cebus_capucinus
ENSG00000111737	RAB35	100	100.000	ENSCATG00000037465	RAB35	100	100.000	Cercocebus_atys
ENSG00000111737	RAB35	100	100.000	ENSCLAG00000013339	RAB35	100	100.000	Chinchilla_lanigera
ENSG00000111737	RAB35	100	100.000	ENSCSAG00000002276	RAB35	100	100.000	Chlorocebus_sabaeus
ENSG00000111737	RAB35	100	99.005	ENSCPBG00000012631	RAB35	100	99.005	Chrysemys_picta_bellii
ENSG00000111737	RAB35	100	92.537	ENSCGRG00001023636	Rab35	100	92.537	Cricetulus_griseus_chok1gshd
ENSG00000111737	RAB35	100	94.030	ENSCSEG00000013400	rab35b	100	94.030	Cynoglossus_semilaevis
ENSG00000111737	RAB35	100	93.532	ENSCVAG00000012806	rab35b	100	93.532	Cyprinodon_variegatus
ENSG00000111737	RAB35	77	99.145	ENSDARG00000102078	CABZ01072548.1	82	93.750	Danio_rerio
ENSG00000111737	RAB35	100	93.035	ENSDARG00000058425	rab35b	100	93.035	Danio_rerio
ENSG00000111737	RAB35	100	100.000	ENSDORG00000000972	Rab35	100	100.000	Dipodomys_ordii
ENSG00000111737	RAB35	100	94.527	ENSELUG00000023972	rab35	100	94.527	Esox_lucius
ENSG00000111737	RAB35	100	100.000	ENSFCAG00000032566	RAB35	100	100.000	Felis_catus
ENSG00000111737	RAB35	92	97.826	ENSFALG00000007652	RAB35	92	93.878	Ficedula_albicollis
ENSG00000111737	RAB35	100	93.035	ENSFHEG00000004891	rab35b	100	93.035	Fundulus_heteroclitus
ENSG00000111737	RAB35	95	94.211	ENSGMOG00000017688	rab35b	100	93.035	Gadus_morhua
ENSG00000111737	RAB35	100	98.507	ENSGALG00000007308	RAB35	100	98.507	Gallus_gallus
ENSG00000111737	RAB35	100	94.030	ENSGACG00000013548	rab35b	100	94.030	Gasterosteus_aculeatus
ENSG00000111737	RAB35	100	99.005	ENSGAGG00000017207	RAB35	100	99.005	Gopherus_agassizii
ENSG00000111737	RAB35	100	94.030	ENSHBUG00000001416	rab35b	100	94.030	Haplochromis_burtoni
ENSG00000111737	RAB35	100	100.000	ENSHGLG00000012703	RAB35	100	100.000	Heterocephalus_glaber_female
ENSG00000111737	RAB35	100	91.045	ENSIPUG00000011489	Rab35	100	91.045	Ictalurus_punctatus
ENSG00000111737	RAB35	100	91.045	ENSIPUG00000024622	rab35	100	91.045	Ictalurus_punctatus
ENSG00000111737	RAB35	100	100.000	ENSJJAG00000010646	Rab35	100	100.000	Jaculus_jaculus
ENSG00000111737	RAB35	100	93.532	ENSKMAG00000006854	rab35b	100	93.532	Kryptolebias_marmoratus
ENSG00000111737	RAB35	100	94.030	ENSLBEG00000001618	rab35b	100	94.030	Labrus_bergylta
ENSG00000111737	RAB35	100	81.373	ENSLACG00000018444	RAB35	100	81.373	Latimeria_chalumnae
ENSG00000111737	RAB35	100	93.035	ENSLOCG00000001637	rab35b	98	93.035	Lepisosteus_oculatus
ENSG00000111737	RAB35	100	100.000	ENSMFAG00000038261	RAB35	100	100.000	Macaca_fascicularis
ENSG00000111737	RAB35	100	100.000	ENSMMUG00000046831	RAB35	100	100.000	Macaca_mulatta
ENSG00000111737	RAB35	100	100.000	ENSMNEG00000043655	RAB35	100	100.000	Macaca_nemestrina
ENSG00000111737	RAB35	100	93.035	ENSMZEG00005002918	rab35b	100	93.035	Maylandia_zebra
ENSG00000111737	RAB35	92	98.370	ENSMGAG00000008922	RAB35	100	98.370	Meleagris_gallopavo
ENSG00000111737	RAB35	100	100.000	ENSMAUG00000009328	Rab35	100	100.000	Mesocricetus_auratus
ENSG00000111737	RAB35	100	99.005	ENSMICG00000047356	RAB35	100	99.005	Microcebus_murinus
ENSG00000111737	RAB35	98	95.408	ENSMOCG00000019999	Rab35	98	95.408	Microtus_ochrogaster
ENSG00000111737	RAB35	77	99.145	ENSMALG00000003479	rab35b	75	99.145	Monopterus_albus
ENSG00000111737	RAB35	100	100.000	MGP_CAROLIEiJ_G0027632	Rab35	100	100.000	Mus_caroli
ENSG00000111737	RAB35	100	100.000	ENSMUSG00000029518	Rab35	100	100.000	Mus_musculus
ENSG00000111737	RAB35	100	100.000	MGP_PahariEiJ_G0024212	Rab35	100	100.000	Mus_pahari
ENSG00000111737	RAB35	100	100.000	MGP_SPRETEiJ_G0028630	Rab35	100	100.000	Mus_spretus
ENSG00000111737	RAB35	100	100.000	ENSODEG00000007219	RAB35	100	100.000	Octodon_degus
ENSG00000111737	RAB35	100	94.030	ENSONIG00000015990	rab35b	100	94.030	Oreochromis_niloticus
ENSG00000111737	RAB35	100	94.527	ENSORLG00000028885	rab35b	100	94.527	Oryzias_latipes
ENSG00000111737	RAB35	100	94.527	ENSORLG00015010042	rab35b	100	94.527	Oryzias_latipes_hsok
ENSG00000111737	RAB35	100	100.000	ENSPPRG00000013225	RAB35	100	100.000	Panthera_pardus
ENSG00000111737	RAB35	100	100.000	ENSPTRG00000005524	RAB35	100	100.000	Pan_troglodytes
ENSG00000111737	RAB35	100	94.030	ENSPKIG00000025079	rab35b	100	94.030	Paramormyrops_kingsleyae
ENSG00000111737	RAB35	100	90.594	ENSPKIG00000016213	-	100	90.594	Paramormyrops_kingsleyae
ENSG00000111737	RAB35	100	93.532	ENSPFOG00000006655	rab35b	100	93.532	Poecilia_formosa
ENSG00000111737	RAB35	100	93.532	ENSPLAG00000020989	rab35b	100	93.532	Poecilia_latipinna
ENSG00000111737	RAB35	100	93.532	ENSPMEG00000021947	rab35b	100	93.532	Poecilia_mexicana
ENSG00000111737	RAB35	100	99.502	ENSPPYG00000005021	RAB35	100	99.502	Pongo_abelii
ENSG00000111737	RAB35	100	99.502	ENSPCOG00000026153	RAB35	100	99.502	Propithecus_coquereli
ENSG00000111737	RAB35	100	99.005	ENSPVAG00000003103	RAB35	100	99.005	Pteropus_vampyrus
ENSG00000111737	RAB35	100	93.532	ENSPNYG00000007156	rab35b	100	93.532	Pundamilia_nyererei
ENSG00000111737	RAB35	100	90.547	ENSPNAG00000014046	-	100	90.547	Pygocentrus_nattereri
ENSG00000111737	RAB35	100	100.000	ENSRNOG00000022014	Rab35	100	100.000	Rattus_norvegicus
ENSG00000111737	RAB35	100	93.532	ENSSFOG00015006076	rab35	100	93.532	Scleropages_formosus
ENSG00000111737	RAB35	100	94.030	ENSSMAG00000000660	rab35b	100	94.030	Scophthalmus_maximus
ENSG00000111737	RAB35	100	94.030	ENSSDUG00000004950	rab35b	100	94.030	Seriola_dumerili
ENSG00000111737	RAB35	100	99.502	ENSSPUG00000016258	RAB35	100	99.502	Sphenodon_punctatus
ENSG00000111737	RAB35	100	94.030	ENSSPAG00000008400	rab35b	100	94.030	Stegastes_partitus
ENSG00000111737	RAB35	100	100.000	ENSSSCG00000033876	RAB35	100	100.000	Sus_scrofa
ENSG00000111737	RAB35	100	97.512	ENSTGUG00000009359	RAB35	100	97.512	Taeniopygia_guttata
ENSG00000111737	RAB35	100	94.030	ENSTRUG00000020633	rab35b	100	94.030	Takifugu_rubripes
ENSG00000111737	RAB35	100	98.010	ENSXETG00000026943	rab35	100	98.010	Xenopus_tropicalis

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000139	Golgi membrane	21873635.	IBA	Component
GO:0000281	mitotic cytokinesis	16950109.	IMP	Process
GO:0003924	GTPase activity	21873635.	IBA	Function
GO:0003924	GTPase activity	17562788.	IDA	Function
GO:0005515	protein binding	17562788.21951725.28230050.	IPI	Function
GO:0005525	GTP binding	20937701.	IDA	Function
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	16950109.	IDA	Function
GO:0005829	cytosol	-	TAS	Component
GO:0005886	plasma membrane	21873635.	IBA	Component
GO:0005886	plasma membrane	16950109.	IDA	Component
GO:0005905	clathrin-coated pit	16950109.	IDA	Component
GO:0006886	intracellular protein transport	21873635.	IBA	Process
GO:0008104	protein localization	16950109.	IMP	Process
GO:0010008	endosome membrane	21873635.	IBA	Component
GO:0010008	endosome membrane	-	ISS	Component
GO:0016197	endosomal transport	16950109.21951725.	IMP	Process
GO:0019003	GDP binding	20937701.	IDA	Function
GO:0019882	antigen processing and presentation	19717423.	IMP	Process
GO:0030665	clathrin-coated vesicle membrane	-	TAS	Component
GO:0031175	neuron projection development	-	ISS	Process
GO:0031253	cell projection membrane	16950109.	IDA	Component
GO:0032456	endocytic recycling	21873635.	IBA	Process
GO:0032482	Rab protein signal transduction	21873635.	IBA	Process
GO:0036010	protein localization to endosome	21951725.	IMP	Process
GO:0042470	melanosome	-	IEA	Component
GO:0045171	intercellular bridge	16950109.	IDA	Component
GO:0045334	clathrin-coated endocytic vesicle	16950109.	IDA	Component
GO:0048227	plasma membrane to endosome transport	17562788.	IMP	Process
GO:0055038	recycling endosome membrane	-	TAS	Component
GO:0070062	extracellular exosome	19056867.20458337.	HDA	Component
GO:0098993	anchored component of synaptic vesicle membrane	-	IEA	Component
GO:1990090	cellular response to nerve growth factor stimulus	-	ISS	Process