EuRBPDB

Description

RBDs

RBPome

Expression

Transcripts

Gene Model

Pathways

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000112110 (Gene tree)
Gene ID: 29074
Gene Symbol: MRPL18
Alias: HSPC071
Full Name: mitochondrial ribosomal protein L18
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Plus strand
Length: 8,625 bases
Position: chr6:159,789,812-159,798,436
Accession: 14477
RBP type: canonical RBP
Summary: This nuclear gene encodes a protein component of the larger 39S subunit of mitochondrial ribosome. This protein may also aid in the import of nuclear-encoded 5S rRNA into mitochondria. Alternative splicing results in multiple transcript variants, most of which are not predicted to encode a protein. A pseudogene of this gene is found on chromosome 16. [provided by RefSeq, Jan 2016]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000356001	Ribosomal_L18p	PF00861.22	5.4e-08	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000479638	MRPL18-203	600	-	-	- (aa)	-	-
ENST00000480842	MRPL18-204	1075	NR_134861	-	- (aa)	-	-
ENST00000476826	MRPL18-202	758	NR_134864	-	- (aa)	-	-
ENST00000367034	MRPL18-201	978	-	ENSP00000356001	180 (aa)	-	Q9H0U6

Gene Model

Click here to download ENSG00000112110's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa03010	Ribosome	KEGG

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000112110's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000112110	MRPL18	84	53.595	ENSAPOG00000017712	mrpl18	81	53.595	Acanthochromis_polyacanthus
ENSG00000112110	MRPL18	100	87.778	ENSAMEG00000015398	MRPL18	100	87.778	Ailuropoda_melanoleuca
ENSG00000112110	MRPL18	84	50.327	ENSACIG00000015656	mrpl18	81	50.327	Amphilophus_citrinellus
ENSG00000112110	MRPL18	84	52.941	ENSAOCG00000001512	mrpl18	81	52.941	Amphiprion_ocellaris
ENSG00000112110	MRPL18	84	52.941	ENSAPEG00000016043	mrpl18	81	52.941	Amphiprion_percula
ENSG00000112110	MRPL18	95	48.256	ENSATEG00000008920	mrpl18	91	49.419	Anabas_testudineus
ENSG00000112110	MRPL18	99	59.358	ENSACAG00000004244	MRPL18	99	59.358	Anolis_carolinensis
ENSG00000112110	MRPL18	100	93.333	ENSANAG00000033398	MRPL18	100	93.333	Aotus_nancymaae
ENSG00000112110	MRPL18	89	50.898	ENSACLG00000009463	mrpl18	88	50.898	Astatotilapia_calliptera
ENSG00000112110	MRPL18	98	46.328	ENSAMXG00000015697	mrpl18	98	44.505	Astyanax_mexicanus
ENSG00000112110	MRPL18	100	85.000	ENSBTAG00000001289	MRPL18	100	85.000	Bos_taurus
ENSG00000112110	MRPL18	100	95.000	ENSCJAG00000011859	MRPL18	100	95.000	Callithrix_jacchus
ENSG00000112110	MRPL18	100	84.021	ENSCAFG00000031434	MRPL18	100	84.021	Canis_familiaris
ENSG00000112110	MRPL18	100	87.778	ENSCAFG00020017736	MRPL18	100	87.778	Canis_lupus_dingo
ENSG00000112110	MRPL18	100	85.556	ENSCHIG00000023286	-	100	85.556	Capra_hircus
ENSG00000112110	MRPL18	90	84.568	ENSCHIG00000025460	-	92	84.568	Capra_hircus
ENSG00000112110	MRPL18	99	87.709	ENSTSYG00000005598	MRPL18	99	87.709	Carlito_syrichta
ENSG00000112110	MRPL18	90	67.284	ENSCAPG00000013467	MRPL18	100	67.284	Cavia_aperea
ENSG00000112110	MRPL18	100	74.146	ENSCPOG00000040103	MRPL18	100	74.146	Cavia_porcellus
ENSG00000112110	MRPL18	100	92.778	ENSCCAG00000027672	MRPL18	100	92.778	Cebus_capucinus
ENSG00000112110	MRPL18	100	95.556	ENSCATG00000039405	MRPL18	100	95.556	Cercocebus_atys
ENSG00000112110	MRPL18	100	76.531	ENSCLAG00000012045	MRPL18	100	76.531	Chinchilla_lanigera
ENSG00000112110	MRPL18	100	96.667	ENSCSAG00000012516	MRPL18	100	96.667	Chlorocebus_sabaeus
ENSG00000112110	MRPL18	100	96.111	ENSCANG00000042891	-	100	96.111	Colobus_angolensis_palliatus
ENSG00000112110	MRPL18	100	91.667	ENSCANG00000029771	-	100	91.667	Colobus_angolensis_palliatus
ENSG00000112110	MRPL18	100	81.111	ENSCGRG00001010667	Mrpl18	100	81.111	Cricetulus_griseus_chok1gshd
ENSG00000112110	MRPL18	100	81.111	ENSCGRG00000008991	Mrpl18	100	81.111	Cricetulus_griseus_crigri
ENSG00000112110	MRPL18	84	52.632	ENSCSEG00000010233	mrpl18	86	52.632	Cynoglossus_semilaevis
ENSG00000112110	MRPL18	84	53.595	ENSCVAG00000011944	mrpl18	81	53.595	Cyprinodon_variegatus
ENSG00000112110	MRPL18	100	87.222	ENSDNOG00000036148	MRPL18	100	87.222	Dasypus_novemcinctus
ENSG00000112110	MRPL18	100	81.667	ENSETEG00000007591	MRPL18	100	81.667	Echinops_telfairi
ENSG00000112110	MRPL18	89	83.851	ENSEASG00005019027	MRPL18	100	83.851	Equus_asinus_asinus
ENSG00000112110	MRPL18	100	85.000	ENSECAG00000012515	MRPL18	94	85.000	Equus_caballus
ENSG00000112110	MRPL18	82	51.351	ENSELUG00000004634	mrpl18	75	51.351	Esox_lucius
ENSG00000112110	MRPL18	100	87.778	ENSFCAG00000002847	MRPL18	100	87.778	Felis_catus
ENSG00000112110	MRPL18	94	70.391	ENSFDAG00000008643	-	99	70.391	Fukomys_damarensis
ENSG00000112110	MRPL18	100	85.000	ENSFDAG00000020747	-	100	85.000	Fukomys_damarensis
ENSG00000112110	MRPL18	73	53.788	ENSFHEG00000018829	mrpl18	71	53.788	Fundulus_heteroclitus
ENSG00000112110	MRPL18	83	52.318	ENSGMOG00000014691	mrpl18	95	52.318	Gadus_morhua
ENSG00000112110	MRPL18	84	50.980	ENSGAFG00000008982	mrpl18	81	50.980	Gambusia_affinis
ENSG00000112110	MRPL18	85	53.247	ENSGACG00000017971	mrpl18	90	53.896	Gasterosteus_aculeatus
ENSG00000112110	MRPL18	100	99.444	ENSGGOG00000014075	MRPL18	100	99.444	Gorilla_gorilla
ENSG00000112110	MRPL18	89	50.898	ENSHBUG00000008534	mrpl18	88	50.898	Haplochromis_burtoni
ENSG00000112110	MRPL18	100	87.222	ENSHGLG00000007214	-	100	87.222	Heterocephalus_glaber_female
ENSG00000112110	MRPL18	100	87.222	ENSHGLG00100017521	-	100	87.222	Heterocephalus_glaber_male
ENSG00000112110	MRPL18	84	48.366	ENSHCOG00000016737	mrpl18	80	48.366	Hippocampus_comes
ENSG00000112110	MRPL18	87	50.000	ENSIPUG00000003341	mrpl18	84	50.000	Ictalurus_punctatus
ENSG00000112110	MRPL18	100	83.333	ENSSTOG00000005583	MRPL18	100	83.333	Ictidomys_tridecemlineatus
ENSG00000112110	MRPL18	77	50.000	ENSKMAG00000010162	mrpl18	88	49.020	Kryptolebias_marmoratus
ENSG00000112110	MRPL18	84	52.941	ENSLBEG00000004268	mrpl18	81	52.941	Labrus_bergylta
ENSG00000112110	MRPL18	78	55.862	ENSLOCG00000008109	mrpl18	81	53.416	Lepisosteus_oculatus
ENSG00000112110	MRPL18	100	84.444	ENSLAFG00000002501	MRPL18	100	84.444	Loxodonta_africana
ENSG00000112110	MRPL18	100	97.222	ENSMFAG00000043173	MRPL18	100	97.222	Macaca_fascicularis
ENSG00000112110	MRPL18	100	95.000	ENSMFAG00000017689	-	100	95.000	Macaca_fascicularis
ENSG00000112110	MRPL18	99	94.972	ENSMMUG00000015343	-	99	94.972	Macaca_mulatta
ENSG00000112110	MRPL18	100	96.667	ENSMNEG00000045344	-	100	96.667	Macaca_nemestrina
ENSG00000112110	MRPL18	85	95.425	ENSMNEG00000044843	-	97	95.425	Macaca_nemestrina
ENSG00000112110	MRPL18	100	96.111	ENSMLEG00000009952	MRPL18	100	96.111	Mandrillus_leucophaeus
ENSG00000112110	MRPL18	84	50.980	ENSMAMG00000006824	mrpl18	81	51.634	Mastacembelus_armatus
ENSG00000112110	MRPL18	89	50.898	ENSMZEG00005013407	mrpl18	88	50.898	Maylandia_zebra
ENSG00000112110	MRPL18	87	79.618	ENSMAUG00000007294	Mrpl18	100	79.618	Mesocricetus_auratus
ENSG00000112110	MRPL18	100	89.444	ENSMICG00000044845	MRPL18	100	89.444	Microcebus_murinus
ENSG00000112110	MRPL18	100	84.444	ENSMOCG00000016680	Mrpl18	100	84.444	Microtus_ochrogaster
ENSG00000112110	MRPL18	90	50.000	ENSMMOG00000003126	mrpl18	88	50.000	Mola_mola
ENSG00000112110	MRPL18	87	73.885	ENSMODG00000007428	MRPL18	92	73.885	Monodelphis_domestica
ENSG00000112110	MRPL18	84	52.258	ENSMALG00000011096	mrpl18	83	52.258	Monopterus_albus
ENSG00000112110	MRPL18	100	82.778	MGP_CAROLIEiJ_G0021044	Mrpl18	100	82.778	Mus_caroli
ENSG00000112110	MRPL18	100	83.333	ENSMUSG00000057388	Mrpl18	100	83.333	Mus_musculus
ENSG00000112110	MRPL18	100	79.006	MGP_PahariEiJ_G0023360	Mrpl18	100	79.006	Mus_pahari
ENSG00000112110	MRPL18	100	83.333	MGP_SPRETEiJ_G0021976	Mrpl18	100	83.333	Mus_spretus
ENSG00000112110	MRPL18	100	85.556	ENSMPUG00000005009	MRPL18	100	85.556	Mustela_putorius_furo
ENSG00000112110	MRPL18	100	81.667	ENSMLUG00000000743	MRPL18	100	81.667	Myotis_lucifugus
ENSG00000112110	MRPL18	100	83.889	ENSNGAG00000020549	Mrpl18	100	83.889	Nannospalax_galili
ENSG00000112110	MRPL18	89	50.299	ENSNBRG00000009833	mrpl18	88	50.299	Neolamprologus_brichardi
ENSG00000112110	MRPL18	100	98.333	ENSNLEG00000011269	MRPL18	100	98.333	Nomascus_leucogenys
ENSG00000112110	MRPL18	100	72.778	ENSMEUG00000011861	MRPL18	100	72.778	Notamacropus_eugenii
ENSG00000112110	MRPL18	100	83.889	ENSOPRG00000003798	MRPL18	100	83.889	Ochotona_princeps
ENSG00000112110	MRPL18	100	80.769	ENSODEG00000006974	-	100	80.769	Octodon_degus
ENSG00000112110	MRPL18	100	84.444	ENSODEG00000007318	-	100	84.444	Octodon_degus
ENSG00000112110	MRPL18	90	87.037	ENSODEG00000014142	-	89	87.037	Octodon_degus
ENSG00000112110	MRPL18	89	51.497	ENSONIG00000004894	mrpl18	89	51.497	Oreochromis_niloticus
ENSG00000112110	MRPL18	100	85.556	ENSOCUG00000013858	MRPL18	100	85.556	Oryctolagus_cuniculus
ENSG00000112110	MRPL18	84	54.248	ENSORLG00000004513	mrpl18	81	54.902	Oryzias_latipes
ENSG00000112110	MRPL18	84	54.248	ENSORLG00020013680	mrpl18	81	54.902	Oryzias_latipes_hni
ENSG00000112110	MRPL18	84	54.248	ENSORLG00015022098	mrpl18	80	54.902	Oryzias_latipes_hsok
ENSG00000112110	MRPL18	84	53.595	ENSOMEG00000004283	mrpl18	81	54.248	Oryzias_melastigma
ENSG00000112110	MRPL18	100	83.889	ENSOGAG00000007327	MRPL18	100	83.889	Otolemur_garnettii
ENSG00000112110	MRPL18	100	85.000	ENSOARG00000004568	MRPL18	100	85.000	Ovis_aries
ENSG00000112110	MRPL18	100	100.000	ENSPPAG00000001652	MRPL18	100	100.000	Pan_paniscus
ENSG00000112110	MRPL18	100	87.222	ENSPPRG00000013063	MRPL18	100	87.222	Panthera_pardus
ENSG00000112110	MRPL18	100	87.222	ENSPTIG00000010107	MRPL18	100	87.222	Panthera_tigris_altaica
ENSG00000112110	MRPL18	100	100.000	ENSPTRG00000018761	MRPL18	100	100.000	Pan_troglodytes
ENSG00000112110	MRPL18	100	96.667	ENSPANG00000024959	-	100	96.667	Papio_anubis
ENSG00000112110	MRPL18	100	96.111	ENSPANG00000023667	-	100	96.111	Papio_anubis
ENSG00000112110	MRPL18	91	42.073	ENSPKIG00000019513	mrpl18	82	42.073	Paramormyrops_kingsleyae
ENSG00000112110	MRPL18	84	50.327	ENSPMGG00000017518	mrpl18	76	50.327	Periophthalmus_magnuspinnatus
ENSG00000112110	MRPL18	100	82.222	ENSPEMG00000016836	Mrpl18	100	82.222	Peromyscus_maniculatus_bairdii
ENSG00000112110	MRPL18	81	57.241	ENSPMAG00000004647	mrpl18	82	53.374	Petromyzon_marinus
ENSG00000112110	MRPL18	96	69.714	ENSPCIG00000003362	MRPL18	97	69.714	Phascolarctos_cinereus
ENSG00000112110	MRPL18	89	48.503	ENSPFOG00000002196	mrpl18	88	48.503	Poecilia_formosa
ENSG00000112110	MRPL18	84	50.327	ENSPLAG00000017970	mrpl18	81	50.327	Poecilia_latipinna
ENSG00000112110	MRPL18	84	50.980	ENSPMEG00000008791	mrpl18	81	50.980	Poecilia_mexicana
ENSG00000112110	MRPL18	84	50.980	ENSPREG00000002415	mrpl18	81	50.980	Poecilia_reticulata
ENSG00000112110	MRPL18	100	98.333	ENSPPYG00000017147	MRPL18	100	98.333	Pongo_abelii
ENSG00000112110	MRPL18	100	89.444	ENSPCOG00000025100	MRPL18	100	89.444	Propithecus_coquereli
ENSG00000112110	MRPL18	100	83.333	ENSPVAG00000005322	MRPL18	100	83.333	Pteropus_vampyrus
ENSG00000112110	MRPL18	89	50.299	ENSPNYG00000000887	mrpl18	88	50.299	Pundamilia_nyererei
ENSG00000112110	MRPL18	84	48.366	ENSPNAG00000019789	mrpl18	86	48.366	Pygocentrus_nattereri
ENSG00000112110	MRPL18	100	81.111	ENSRNOG00000014582	Mrpl18	100	81.111	Rattus_norvegicus
ENSG00000112110	MRPL18	100	85.000	ENSRBIG00000038575	-	100	85.000	Rhinopithecus_bieti
ENSG00000112110	MRPL18	91	93.865	ENSRBIG00000039702	-	98	93.865	Rhinopithecus_bieti
ENSG00000112110	MRPL18	100	96.111	ENSRROG00000030298	MRPL18	100	96.111	Rhinopithecus_roxellana
ENSG00000112110	MRPL18	100	93.889	ENSSBOG00000017384	MRPL18	100	93.889	Saimiri_boliviensis_boliviensis
ENSG00000112110	MRPL18	84	44.444	ENSSFOG00015001208	mrpl18	76	44.444	Scleropages_formosus
ENSG00000112110	MRPL18	92	48.824	ENSSMAG00000002207	mrpl18	90	48.824	Scophthalmus_maximus
ENSG00000112110	MRPL18	84	51.634	ENSSDUG00000003242	mrpl18	81	51.634	Seriola_dumerili
ENSG00000112110	MRPL18	84	52.288	ENSSLDG00000002846	mrpl18	81	52.288	Seriola_lalandi_dorsalis
ENSG00000112110	MRPL18	84	53.595	ENSSPAG00000008506	mrpl18	81	53.595	Stegastes_partitus
ENSG00000112110	MRPL18	100	88.333	ENSSSCG00000004047	MRPL18	100	88.333	Sus_scrofa
ENSG00000112110	MRPL18	89	49.102	ENSTRUG00000024901	mrpl18	90	49.102	Takifugu_rubripes
ENSG00000112110	MRPL18	84	49.673	ENSTNIG00000014217	mrpl18	82	50.327	Tetraodon_nigroviridis
ENSG00000112110	MRPL18	100	87.222	ENSTTRG00000010404	MRPL18	100	87.222	Tursiops_truncatus
ENSG00000112110	MRPL18	100	82.474	ENSUAMG00000015786	MRPL18	100	82.474	Ursus_americanus
ENSG00000112110	MRPL18	100	82.474	ENSUMAG00000011916	MRPL18	100	82.474	Ursus_maritimus
ENSG00000112110	MRPL18	78	88.571	ENSVPAG00000008211	MRPL18	100	88.571	Vicugna_pacos
ENSG00000112110	MRPL18	100	81.959	ENSVVUG00000006607	MRPL18	100	81.959	Vulpes_vulpes
ENSG00000112110	MRPL18	89	62.112	ENSXETG00000023893	mrpl18	92	62.112	Xenopus_tropicalis
ENSG00000112110	MRPL18	84	51.634	ENSXCOG00000003125	mrpl18	81	51.634	Xiphophorus_couchianus
ENSG00000112110	MRPL18	84	50.980	ENSXMAG00000029792	MRPL18	81	50.980	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0003735	structural constituent of ribosome	11543634.	NAS	Function
GO:0005615	extracellular space	22664934.	HDA	Component
GO:0005739	mitochondrion	21873635.	IBA	Component
GO:0005739	mitochondrion	28892042.	IDA	Component
GO:0005743	mitochondrial inner membrane	-	TAS	Component
GO:0005761	mitochondrial ribosome	11543634.	NAS	Component
GO:0005762	mitochondrial large ribosomal subunit	25278503.28892042.	IDA	Component
GO:0006412	translation	11543634.	NAS	Process
GO:0008097	5S rRNA binding	21873635.	IBA	Function
GO:0008097	5S rRNA binding	21685364.	IDA	Function
GO:0035928	rRNA import into mitochondrion	21685364.	IDA	Process
GO:0070125	mitochondrial translational elongation	-	TAS	Process
GO:0070126	mitochondrial translational termination	-	TAS	Process