EuRBPDB

Description

RBDs

RBPome

Literatures

Expression

Transcripts

Gene Model

Phenotypes

GWAS

PPI

Paralogs

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000112249 (Gene tree)
Gene ID: 10973
Gene Symbol: ASCC3
Alias: RNAH|ASC1p200|dJ121G13.4|dJ467N11.1|HELIC1
Full Name: activating signal cointegrator 1 complex subunit 3
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Minus strand
Length: 373,179 bases
Position: chr6:100,508,194-100,881,372
Accession: 18697
RBP type: canonical RBP
Summary: This gene encodes a protein that belongs to a family of helicases that are involved in the ATP-dependent unwinding of nucleic acid duplexes. The encoded protein is the largest subunit of the activating signal cointegrator 1 complex that is involved in DNA repair and resistance to alkylation damage. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000358159	ResIII	PF04851.15	1e-25	1	2
ENSP00000358159	ResIII	PF04851.15	1e-25	2	2
ENSP00000430769	ResIII	PF04851.15	2.3e-12	1	1
ENSP00000358159	DEAD	PF00270.29	3.2e-52	1	2
ENSP00000358159	DEAD	PF00270.29	3.2e-52	2	2
ENSP00000430769	DEAD	PF00270.29	1.5e-26	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
22681889	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts	4SURIC & HEK293	2012 May	Baltz AG	DOI: 10.1016/j.molcel.2012.05.021
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
29431736	Capturing the interactome of newly transcribed RNA	PolyT-RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	RIC & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30352994	Discovery of RNA-binding proteins and characterization of their dynamic responses by enhanced RNA interactome capture	RIC & Jurkat	2018 Oct 23	Perez-Perri JI	DOI:10.1038/s41467-018-06557-8

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
11087862	Crystal structure of yeast initiation factor 4A, a DEAD-box RNA helicase.	Proc Natl Acad Sci U S A	2000 Nov 21	Caruthers JM	-
15528191	Interaction between the NH2-terminal domain of eIF4A and the central domain of eIF4G modulates RNA-stimulated ATPase activity.	J Biol Chem	2005 Jan 21	Korneeva NL	-
24450646	The diverse roles of the eIF4A family: you are the company you keep.	Biochem Soc Trans	2014 Feb	Lu WT	doi: 10.1042/BST20130161.
12649492	RNA aptamers to initiation factor 4A helicase hinder cap-dependent translation by blocking ATP hydrolysis.	RNA	2003 Apr	Oguro A	-
27586307	DDX3X promotes the biogenesis of a subset of miRNAs and the potential roles they played in cancer development.	Sci Rep	2016 Sep 2	Zhao L	doi: 10.1038/srep32739.
15375644	Random transposon mutagenesis of Lactobacillus plantarum by using the pGh9:IS S1 vector to clone genes involved in the regulation of phenolic acid metabolism.	Arch Microbiol	2004 Nov	Gury J	-
28757607	Ubiquitination of stalled ribosome triggers ribosome-associated quality control.	Nat Commun	2017 Jul 31	Matsuo Y	doi: 10.1038/s41467-017-00188-1.
17971306	Mouse nucleolin binds to 4.5S RNAh, a small noncoding RNA.	Biochem Biophys Res Commun	2008 Jan 4	Hirose Y	-

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000522650	ASCC3-207	2828	-	ENSP00000430769	731 (aa)	-	Q8N3C0
ENST00000369162	ASCC3-204	8146	XM_011535394	ENSP00000358159	2202 (aa)	XP_011533696	Q8N3C0
ENST00000518006	ASCC3-206	693	-	-	- (aa)	-	-
ENST00000324696	ASCC3-201	3618	-	ENSP00000320252	48 (aa)	-	J3KNJ4
ENST00000324723	ASCC3-202	852	-	ENSP00000320777	176 (aa)	-	E5RFZ0
ENST00000369143	ASCC3-203	3433	-	ENSP00000358139	111 (aa)	-	Q8N3C0
ENST00000468245	ASCC3-205	1227	-	-	- (aa)	-	-

Gene Model

Click here to download ENSG00000112249's gene model file

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000112249	Body Mass Index	3.781050115391E-7	17903300
ENSG00000112249	Body Weight	7.63194051628506E-10	17903300
ENSG00000112249	Triglycerides	6.09764165679927E-5	17903299
ENSG00000112249	Carotid Arteries	1.04744036656547E-5	17903303
ENSG00000112249	Hip	5.63873950742033E-7	17903296
ENSG00000112249	Memory	1.16719398144423E-6	17903297
ENSG00000112249	Stroke	6.6811877E-006	19369658
ENSG00000112249	Iron	7.802e-005	-
ENSG00000112249	Creatinine	5.2970000E-005	-
ENSG00000112249	Menarche	3E-8	25231870
ENSG00000112249	Biomarkers	1E-7	22797727
ENSG00000112249	coenzyme Q10	5E-6	27149984
ENSG00000112249	Surveys and Questionnaires	2E-6	22566634

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000112249	rs17672112	6	100826813	?	Putamen volume	29147026	[18.87-48.28] mm3 decrease	33.573	EFO_0006932
ENSG00000112249	rs239198	6	100686201	T	Menarche (age at onset)	25231870	[0.02-0.04] unit increase	0.03	EFO_0004703
ENSG00000112249	rs240768	6	100509468	T	Economic and political preferences (immigration/crime)	22566634	[0.16-0.38] unit increase	0.267	EFO_0004827
ENSG00000112249	rs240110	6	100611753	T	Neuroticism	29255261	z score increase	5.245	EFO_0007660
ENSG00000112249	rs240769	6	100564311	A	Neurociticism	29500382	z score decrease	5.84	EFO_0007660
ENSG00000112249	rs240769	6	100564311	A	Neuroticism	29942085	z score decrease	5.635	EFO_0007660
ENSG00000112249	rs12206564	6	100539133	?	Menarche (age at onset)	30595370			EFO_0004703
ENSG00000112249	rs180963	6	100679337	?	Body mass index	30595370			EFO_0004340
ENSG00000112249	rs239245	6	100642501	A	Smoking status (ever vs never smokers)	30643258	[0.0073-0.0152] unit decrease	0.01124458	EFO_0004318
ENSG00000112249	rs6932158	6	100798134	?	Smoking status	30595370			EFO_0006527
ENSG00000112249	rs6932158	6	100798134	C	Insomnia symptoms (never/rarely vs. usually)	30804566	[1.01-1.04]	1.03	EFO_0007876
ENSG00000112249	rs6932158	6	100798134	C	Insomnia symptoms (never/rarely vs. sometimes/usually)	30804566	[1.01-1.04]	1.03	EFO_0007876
ENSG00000112249	rs4461738	6	100530064	C	Neuroticism	30643256	[0.006-0.0118] unit increase	0.008925479	EFO_0007660
ENSG00000112249	rs4461738	6	100530064	C	Depressive symptoms	30643256	[0.0039-0.0075] unit increase	0.005709739	EFO_0007006
ENSG00000112249	rs240788	6	100536230	?	Neuroticism	30595370			EFO_0007660
ENSG00000112249	rs4461738	6	100530064	C	Well-being spectrum (multivariate analysis)	30643256	[0.0038-0.0074] unit increase	0.005637865	EFO_0007869
ENSG00000112249	rs4461738	6	100530064	C	Life satisfaction	30643256	[0.0049-0.0097] unit increase	0.007290558	EFO_0007869
ENSG00000112249	rs4461738	6	100530064	C	Positive affect	30643256	[0.0046-0.0091] unit increase	0.006865592	EFO_0007869
ENSG00000112249	rs12530388	6	100881297	C	Smoking initiation (ever regular vs never regular)	30643251	[0.013-0.023] unit decrease	0.01836168	EFO_0006527

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000112249's network

* RBP PPI network refers to all genes directly bind to RBP

Paralogs

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy
ENSG00000112249	ASCC3	80	44.463	ENSG00000144028	SNRNP200	84	47.189

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000112249	ASCC3	100	92.688	ENSAMEG00000014749	ASCC3	100	92.688	Ailuropoda_melanoleuca
ENSG00000112249	ASCC3	98	71.501	ENSACIG00000004551	ascc3	99	71.501	Amphilophus_citrinellus
ENSG00000112249	ASCC3	99	73.399	ENSAOCG00000005106	ascc3	99	73.823	Amphiprion_ocellaris
ENSG00000112249	ASCC3	96	74.361	ENSAPEG00000006181	ascc3	99	74.409	Amphiprion_percula
ENSG00000112249	ASCC3	99	72.871	ENSATEG00000024950	ascc3	99	72.871	Anabas_testudineus
ENSG00000112249	ASCC3	88	85.537	ENSAPLG00000012589	-	99	85.537	Anas_platyrhynchos
ENSG00000112249	ASCC3	100	81.946	ENSACAG00000010080	ASCC3	100	81.946	Anolis_carolinensis
ENSG00000112249	ASCC3	100	97.866	ENSANAG00000021476	ASCC3	100	97.866	Aotus_nancymaae
ENSG00000112249	ASCC3	87	77.007	ENSACLG00000006736	ascc3	98	77.059	Astatotilapia_calliptera
ENSG00000112249	ASCC3	100	71.783	ENSAMXG00000001395	ascc3	100	71.944	Astyanax_mexicanus
ENSG00000112249	ASCC3	100	91.780	ENSBTAG00000020482	ASCC3	100	91.780	Bos_taurus
ENSG00000112249	ASCC3	88	47.170	WBGene00013189	Y54E2A.4	99	45.310	Caenorhabditis_elegans
ENSG00000112249	ASCC3	100	97.593	ENSCJAG00000001507	ASCC3	100	98.162	Callithrix_jacchus
ENSG00000112249	ASCC3	100	92.371	ENSCAFG00000003554	ASCC3	100	92.371	Canis_familiaris
ENSG00000112249	ASCC3	100	92.325	ENSCAFG00020016899	ASCC3	100	92.325	Canis_lupus_dingo
ENSG00000112249	ASCC3	100	91.916	ENSCHIG00000023605	ASCC3	100	91.916	Capra_hircus
ENSG00000112249	ASCC3	100	96.591	ENSTSYG00000006324	ASCC3	100	96.378	Carlito_syrichta
ENSG00000112249	ASCC3	92	88.644	ENSCAPG00000010888	ASCC3	99	88.644	Cavia_aperea
ENSG00000112249	ASCC3	99	92.601	ENSCPOG00000013989	ASCC3	100	92.601	Cavia_porcellus
ENSG00000112249	ASCC3	100	98.093	ENSCCAG00000024230	ASCC3	100	98.093	Cebus_capucinus
ENSG00000112249	ASCC3	100	98.910	ENSCATG00000011281	ASCC3	100	98.910	Cercocebus_atys
ENSG00000112249	ASCC3	100	93.872	ENSCLAG00000009794	ASCC3	100	93.872	Chinchilla_lanigera
ENSG00000112249	ASCC3	100	98.819	ENSCSAG00000014674	ASCC3	100	98.819	Chlorocebus_sabaeus
ENSG00000112249	ASCC3	100	82.955	ENSCHOG00000002063	ASCC3	85	84.551	Choloepus_hoffmanni
ENSG00000112249	ASCC3	100	83.529	ENSCPBG00000003881	ASCC3	100	83.529	Chrysemys_picta_bellii
ENSG00000112249	ASCC3	82	60.166	ENSCSAVG00000007670	-	100	68.545	Ciona_savignyi
ENSG00000112249	ASCC3	100	99.092	ENSCANG00000004215	ASCC3	100	99.092	Colobus_angolensis_palliatus
ENSG00000112249	ASCC3	99	92.598	ENSCGRG00001000918	Ascc3	100	92.598	Cricetulus_griseus_chok1gshd
ENSG00000112249	ASCC3	99	92.779	ENSCGRG00000012933	Ascc3	100	92.779	Cricetulus_griseus_crigri
ENSG00000112249	ASCC3	99	73.230	ENSCSEG00000012811	ascc3	99	73.068	Cynoglossus_semilaevis
ENSG00000112249	ASCC3	99	71.616	ENSCVAG00000013014	ascc3	99	71.661	Cyprinodon_variegatus
ENSG00000112249	ASCC3	92	72.718	ENSDARG00000086678	ascc3	100	85.522	Danio_rerio
ENSG00000112249	ASCC3	100	84.091	ENSDNOG00000010279	ASCC3	99	95.789	Dasypus_novemcinctus
ENSG00000112249	ASCC3	100	93.827	ENSDORG00000008572	Ascc3	100	93.827	Dipodomys_ordii
ENSG00000112249	ASCC3	89	54.209	FBgn0038344	obe	89	54.342	Drosophila_melanogaster
ENSG00000112249	ASCC3	86	97.516	ENSETEG00000010694	-	75	97.068	Echinops_telfairi
ENSG00000112249	ASCC3	54	78.522	ENSEBUG00000007355	-	99	78.522	Eptatretus_burgeri
ENSG00000112249	ASCC3	100	92.461	ENSEASG00005006324	ASCC3	100	92.461	Equus_asinus_asinus
ENSG00000112249	ASCC3	100	92.507	ENSECAG00000012013	ASCC3	100	92.507	Equus_caballus
ENSG00000112249	ASCC3	87	82.622	ENSEEUG00000009748	ASCC3	99	82.622	Erinaceus_europaeus
ENSG00000112249	ASCC3	100	72.805	ENSELUG00000023441	ascc3	100	72.805	Esox_lucius
ENSG00000112249	ASCC3	100	92.825	ENSFCAG00000031266	ASCC3	100	92.825	Felis_catus
ENSG00000112249	ASCC3	100	82.776	ENSFALG00000005260	ASCC3	100	82.776	Ficedula_albicollis
ENSG00000112249	ASCC3	100	93.055	ENSFDAG00000011358	ASCC3	100	93.055	Fukomys_damarensis
ENSG00000112249	ASCC3	99	72.982	ENSFHEG00000019247	ascc3	99	79.873	Fundulus_heteroclitus
ENSG00000112249	ASCC3	98	71.192	ENSGMOG00000018158	ascc3	99	71.238	Gadus_morhua
ENSG00000112249	ASCC3	100	83.047	ENSGALG00000015465	ASCC3	100	83.047	Gallus_gallus
ENSG00000112249	ASCC3	100	72.468	ENSGACG00000014141	ascc3	100	72.514	Gasterosteus_aculeatus
ENSG00000112249	ASCC3	99	78.356	ENSGAGG00000020794	ASCC3	99	85.783	Gopherus_agassizii
ENSG00000112249	ASCC3	100	99.637	ENSGGOG00000002790	ASCC3	100	99.637	Gorilla_gorilla
ENSG00000112249	ASCC3	99	63.611	ENSHBUG00000015110	ascc3	98	73.556	Haplochromis_burtoni
ENSG00000112249	ASCC3	100	93.645	ENSHGLG00000002093	ASCC3	100	93.645	Heterocephalus_glaber_female
ENSG00000112249	ASCC3	99	91.460	ENSHGLG00100005896	ASCC3	100	91.460	Heterocephalus_glaber_male
ENSG00000112249	ASCC3	99	72.904	ENSHCOG00000021142	ascc3	100	72.904	Hippocampus_comes
ENSG00000112249	ASCC3	100	74.243	ENSIPUG00000013863	ascc3	100	74.288	Ictalurus_punctatus
ENSG00000112249	ASCC3	99	92.798	ENSSTOG00000006645	ASCC3	100	92.779	Ictidomys_tridecemlineatus
ENSG00000112249	ASCC3	100	92.556	ENSJJAG00000022570	Ascc3	100	92.556	Jaculus_jaculus
ENSG00000112249	ASCC3	99	73.192	ENSKMAG00000003953	ascc3	99	73.237	Kryptolebias_marmoratus
ENSG00000112249	ASCC3	85	77.861	ENSLBEG00000009623	ascc3	99	77.914	Labrus_bergylta
ENSG00000112249	ASCC3	75	81.942	ENSLACG00000015253	ascc3	100	81.942	Latimeria_chalumnae
ENSG00000112249	ASCC3	100	61.582	ENSLACG00000012281	-	100	67.282	Latimeria_chalumnae
ENSG00000112249	ASCC3	100	77.142	ENSLOCG00000016550	ascc3	100	77.142	Lepisosteus_oculatus
ENSG00000112249	ASCC3	100	77.273	ENSLAFG00000011363	ASCC3	100	79.279	Loxodonta_africana
ENSG00000112249	ASCC3	100	98.910	ENSMFAG00000002081	ASCC3	100	98.910	Macaca_fascicularis
ENSG00000112249	ASCC3	100	98.955	ENSMMUG00000022287	ASCC3	100	98.955	Macaca_mulatta
ENSG00000112249	ASCC3	100	98.865	ENSMNEG00000032760	ASCC3	100	98.865	Macaca_nemestrina
ENSG00000112249	ASCC3	100	98.864	ENSMLEG00000035241	ASCC3	100	97.601	Mandrillus_leucophaeus
ENSG00000112249	ASCC3	99	73.249	ENSMAMG00000005917	ascc3	99	73.249	Mastacembelus_armatus
ENSG00000112249	ASCC3	76	80.791	ENSMZEG00005002710	ascc3	74	80.855	Maylandia_zebra
ENSG00000112249	ASCC3	100	82.023	ENSMGAG00000013551	ASCC3	100	82.023	Meleagris_gallopavo
ENSG00000112249	ASCC3	99	93.188	ENSMAUG00000018304	Ascc3	100	93.188	Mesocricetus_auratus
ENSG00000112249	ASCC3	100	97.159	ENSMICG00000008861	ASCC3	100	96.549	Microcebus_murinus
ENSG00000112249	ASCC3	100	92.510	ENSMOCG00000004549	Ascc3	100	92.510	Microtus_ochrogaster
ENSG00000112249	ASCC3	96	70.199	ENSMMOG00000003198	ascc3	99	70.199	Mola_mola
ENSG00000112249	ASCC3	100	86.691	ENSMODG00000018082	ASCC3	99	86.691	Monodelphis_domestica
ENSG00000112249	ASCC3	96	70.771	ENSMALG00000015536	ascc3	99	70.878	Monopterus_albus
ENSG00000112249	ASCC3	99	92.598	MGP_CAROLIEiJ_G0015302	Ascc3	100	92.598	Mus_caroli
ENSG00000112249	ASCC3	99	92.144	ENSMUSG00000038774	Ascc3	100	92.144	Mus_musculus
ENSG00000112249	ASCC3	99	92.234	MGP_SPRETEiJ_G0016111	Ascc3	100	92.234	Mus_spretus
ENSG00000112249	ASCC3	100	92.461	ENSMPUG00000001675	ASCC3	100	92.461	Mustela_putorius_furo
ENSG00000112249	ASCC3	100	91.466	ENSMLUG00000002886	ASCC3	100	91.466	Myotis_lucifugus
ENSG00000112249	ASCC3	100	93.327	ENSNGAG00000000702	Ascc3	100	93.327	Nannospalax_galili
ENSG00000112249	ASCC3	84	67.378	ENSNBRG00000022083	ascc3	92	67.378	Neolamprologus_brichardi
ENSG00000112249	ASCC3	100	100.000	ENSNLEG00000013890	ASCC3	100	99.410	Nomascus_leucogenys
ENSG00000112249	ASCC3	97	94.737	ENSMEUG00000003061	ASCC3	83	94.737	Notamacropus_eugenii
ENSG00000112249	ASCC3	100	88.636	ENSOPRG00000010249	-	79	96.000	Ochotona_princeps
ENSG00000112249	ASCC3	100	93.463	ENSODEG00000000069	ASCC3	100	93.463	Octodon_degus
ENSG00000112249	ASCC3	99	72.863	ENSONIG00000016540	ascc3	99	72.908	Oreochromis_niloticus
ENSG00000112249	ASCC3	100	84.608	ENSOANG00000008944	ASCC3	100	84.608	Ornithorhynchus_anatinus
ENSG00000112249	ASCC3	99	94.270	ENSOCUG00000002766	ASCC3	100	94.361	Oryctolagus_cuniculus
ENSG00000112249	ASCC3	95	73.387	ENSORLG00000004221	ascc3	99	73.340	Oryzias_latipes
ENSG00000112249	ASCC3	86	78.613	ENSORLG00020022595	ascc3	97	78.613	Oryzias_latipes_hni
ENSG00000112249	ASCC3	95	73.435	ENSORLG00015009231	ascc3	99	73.387	Oryzias_latipes_hsok
ENSG00000112249	ASCC3	99	72.240	ENSOMEG00000019630	ascc3	100	72.240	Oryzias_melastigma
ENSG00000112249	ASCC3	99	91.828	ENSOGAG00000009875	ASCC3	100	93.996	Otolemur_garnettii
ENSG00000112249	ASCC3	100	91.871	ENSOARG00000011627	ASCC3	100	91.871	Ovis_aries
ENSG00000112249	ASCC3	100	99.728	ENSPPAG00000030772	ASCC3	100	99.728	Pan_paniscus
ENSG00000112249	ASCC3	100	92.688	ENSPPRG00000011358	ASCC3	100	92.688	Panthera_pardus
ENSG00000112249	ASCC3	100	92.552	ENSPTIG00000006331	ASCC3	100	92.552	Panthera_tigris_altaica
ENSG00000112249	ASCC3	100	100.000	ENSPTRG00000018448	ASCC3	100	99.728	Pan_troglodytes
ENSG00000112249	ASCC3	100	98.819	ENSPANG00000006307	ASCC3	100	98.819	Papio_anubis
ENSG00000112249	ASCC3	99	73.613	ENSPKIG00000013639	ascc3	100	73.670	Paramormyrops_kingsleyae
ENSG00000112249	ASCC3	98	78.464	ENSPSIG00000002623	-	100	78.464	Pelodiscus_sinensis
ENSG00000112249	ASCC3	78	85.684	ENSPSIG00000002620	-	96	85.684	Pelodiscus_sinensis
ENSG00000112249	ASCC3	100	93.182	ENSPEMG00000015319	Ascc3	100	93.233	Peromyscus_maniculatus_bairdii
ENSG00000112249	ASCC3	69	79.543	ENSPMAG00000002163	-	100	79.543	Petromyzon_marinus
ENSG00000112249	ASCC3	100	86.827	ENSPCIG00000017288	ASCC3	99	86.997	Phascolarctos_cinereus
ENSG00000112249	ASCC3	89	74.477	ENSPFOG00000001462	ascc3	99	74.528	Poecilia_formosa
ENSG00000112249	ASCC3	99	72.995	ENSPREG00000017616	ascc3	99	73.040	Poecilia_reticulata
ENSG00000112249	ASCC3	100	100.000	ENSPPYG00000016869	ASCC3	100	97.775	Pongo_abelii
ENSG00000112249	ASCC3	100	81.162	ENSPCAG00000008834	ASCC3	100	81.162	Procavia_capensis
ENSG00000112249	ASCC3	100	85.014	ENSPVAG00000012827	ASCC3	100	85.014	Pteropus_vampyrus
ENSG00000112249	ASCC3	88	76.205	ENSPNYG00000018913	ascc3	99	76.256	Pundamilia_nyererei
ENSG00000112249	ASCC3	86	79.407	ENSPNAG00000016413	ascc3	98	79.376	Pygocentrus_nattereri
ENSG00000112249	ASCC3	99	92.640	ENSRNOG00000037604	Ascc3	100	92.640	Rattus_norvegicus
ENSG00000112249	ASCC3	99	95.724	ENSRBIG00000038415	-	100	95.724	Rhinopithecus_bieti
ENSG00000112249	ASCC3	100	99.046	ENSRROG00000045402	ASCC3	100	99.046	Rhinopithecus_roxellana
ENSG00000112249	ASCC3	72	48.327	YGR271W	-	81	48.327	Saccharomyces_cerevisiae
ENSG00000112249	ASCC3	100	97.866	ENSSBOG00000025142	ASCC3	100	97.866	Saimiri_boliviensis_boliviensis
ENSG00000112249	ASCC3	100	86.458	ENSSHAG00000016496	ASCC3	100	86.549	Sarcophilus_harrisii
ENSG00000112249	ASCC3	99	73.385	ENSSFOG00015010273	ascc3	99	73.385	Scleropages_formosus
ENSG00000112249	ASCC3	99	73.023	ENSSMAG00000012927	ascc3	99	73.204	Scophthalmus_maximus
ENSG00000112249	ASCC3	99	73.675	ENSSDUG00000010897	ascc3	99	73.675	Seriola_dumerili
ENSG00000112249	ASCC3	99	73.617	ENSSLDG00000021782	ascc3	99	73.617	Seriola_lalandi_dorsalis
ENSG00000112249	ASCC3	98	89.136	ENSSARG00000001858	ASCC3	92	87.055	Sorex_araneus
ENSG00000112249	ASCC3	100	83.183	ENSSPUG00000001842	ASCC3	100	83.183	Sphenodon_punctatus
ENSG00000112249	ASCC3	99	73.421	ENSSPAG00000007677	ascc3	99	73.466	Stegastes_partitus
ENSG00000112249	ASCC3	100	91.875	ENSSSCG00000004358	ASCC3	100	91.875	Sus_scrofa
ENSG00000112249	ASCC3	90	84.168	ENSTGUG00000012262	ASCC3	99	84.168	Taeniopygia_guttata
ENSG00000112249	ASCC3	98	67.265	ENSTNIG00000005079	ascc3	100	67.480	Tetraodon_nigroviridis
ENSG00000112249	ASCC3	91	100.000	ENSTBEG00000015236	ASCC3	86	100.000	Tupaia_belangeri
ENSG00000112249	ASCC3	100	91.077	ENSTTRG00000008255	ASCC3	96	91.077	Tursiops_truncatus
ENSG00000112249	ASCC3	69	96.933	ENSUAMG00000023340	-	98	96.933	Ursus_americanus
ENSG00000112249	ASCC3	100	91.735	ENSUMAG00000021200	ASCC3	100	91.735	Ursus_maritimus
ENSG00000112249	ASCC3	99	89.320	ENSVPAG00000001408	ASCC3	100	87.835	Vicugna_pacos
ENSG00000112249	ASCC3	100	92.461	ENSVVUG00000015397	ASCC3	100	93.287	Vulpes_vulpes
ENSG00000112249	ASCC3	80	81.410	ENSXETG00000032212	-	100	81.410	Xenopus_tropicalis
ENSG00000112249	ASCC3	100	64.305	ENSXETG00000002407	ascc3	99	64.463	Xenopus_tropicalis
ENSG00000112249	ASCC3	99	73.098	ENSXMAG00000000071	ascc3	100	73.143	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0003723	RNA binding	22681889.	HDA	Function
GO:0005515	protein binding	22055184.	IPI	Function
GO:0005524	ATP binding	-	IEA	Function
GO:0005634	nucleus	21873635.	IBA	Component
GO:0005634	nucleus	12077347.	IDA	Component
GO:0005634	nucleus	22055184.	TAS	Component
GO:0005654	nucleoplasm	-	TAS	Component
GO:0005829	cytosol	-	IDA	Component
GO:0006307	DNA dealkylation involved in DNA repair	21873635.	IBA	Process
GO:0006307	DNA dealkylation involved in DNA repair	22055184.	IDA	Process
GO:0006307	DNA dealkylation involved in DNA repair	-	TAS	Process
GO:0008026	ATP-dependent helicase activity	21873635.	IBA	Function
GO:0008283	cell proliferation	22055184.	IMP	Process
GO:0016020	membrane	19946888.	HDA	Component
GO:0016607	nuclear speck	-	IEA	Component
GO:0032508	DNA duplex unwinding	22055184.	IDA	Process
GO:0043140	ATP-dependent 3'-5' DNA helicase activity	21873635.	IBA	Function
GO:0043140	ATP-dependent 3'-5' DNA helicase activity	22055184.	IDA	Function
GO:0099053	activating signal cointegrator 1 complex	12077347.	IDA	Component