EuRBPDB

Description

Ensembl ID: ENSG00000112305 (Gene tree)
Gene ID: 60682
Gene Symbol: SMAP1
Alias: FLJ13159|SMAP-1
Full Name: small ArfGAP 1
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Plus strand
Length: 194,245 bases
Position: chr6:70,667,771-70,862,015
Accession: 19651
RBP type: non-canonical RBP
Summary: The protein encoded by this gene is similar to the mouse stromal membrane-associated protein-1. This similarity suggests that this human gene product is also a type II membrane glycoprotein involved in the erythropoietic stimulatory activity of stromal cells. Alternate splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000439432	SMAP1-204	419	-	ENSP00000398306	125 (aa)	-	H0Y5G0
ENST00000316999	SMAP1-201	2403	-	ENSP00000313382	440 (aa)	-	Q8IYB5
ENST00000445046	SMAP1-205	578	-	ENSP00000415426	62 (aa)	-	Q5T6I8
ENST00000619054	SMAP1-206	3150	-	ENSP00000484538	457 (aa)	-	A0A087X1X9
ENST00000370452	SMAP1-202	2491	XM_011536047	ENSP00000359481	436 (aa)	XP_011534349	Q8IYB5
ENST00000370455	SMAP1-203	3333	XM_011536045	ENSP00000359484	467 (aa)	XP_011534347	Q8IYB5

Gene Model

Pathways

Pathway ID	Pathway Name	Source
hsa04144	Endocytosis	KEGG

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000112305	CD40 Ligand	7.18726318057076E-5	17903293
ENSG00000112305	CD40 Ligand	3.47305821472081E-5	17903293
ENSG00000112305	CD40 Ligand	4.0256947895001E-5	17903293
ENSG00000112305	CD40 Ligand	5.91942553778022E-5	17903293
ENSG00000112305	CD40 Ligand	2.63400588703351E-5	17903293
ENSG00000112305	CD40 Ligand	3.14093367663748E-5	17903293

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000112305	rs61400090	6	70819329	G	Blood protein levels	29875488	[0.14-0.22] unit increase	0.18	EFO_0007937

Protein-Protein Interaction (PPI)

* RBP PPI network refers to all genes directly bind to RBP

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0005096	GTPase activator activity	-	IEA	Function
GO:0005737	cytoplasm	-	IEA	Component
GO:0005886	plasma membrane	-	IEA	Component
GO:0030276	clathrin binding	-	IEA	Function
GO:0043547	positive regulation of GTPase activity	-	IEA	Process
GO:0045648	positive regulation of erythrocyte differentiation	-	IEA	Process
GO:0046872	metal ion binding	-	IEA	Function
GO:2000369	regulation of clathrin-dependent endocytosis	21873635.	IBA	Process