EuRBPDB

Description

RBDs

RBPome

Literatures

Expression

Transcripts

Gene Model

Pathways

Phenotypes

GWAS

PPI

Paralogs

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000112339 (Gene tree)
Gene ID: 10767
Gene Symbol: HBS1L
Alias: ERFS|HBS1|HSPC276|KIAA1038|DKFZp434g247|EF-1a|eRF3c
Full Name: HBS1 like translational GTPase
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Minus strand
Length: 142,679 bases
Position: chr6:134,960,378-135,103,056
Accession: 4834
RBP type: canonical RBP
Summary: This gene encodes a member of the GTP-binding elongation factor family. It is expressed in multiple tissues with the highest expression in heart and skeletal muscle. The intergenic region of this gene and the MYB gene has been identified to be a quantitative trait locus (QTL) controlling fetal hemoglobin level, and this region influnces erythrocyte, platelet, and monocyte counts as well as erythrocyte volume and hemoglobin content. DNA polymorphisms at this region associate with fetal hemoglobin levels and pain crises in sickle cell disease. A single nucleotide polymorphism in exon 1 of this gene is significantly associated with severity in beta-thalassemia/Hemoglobin E. Multiple alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq, May 2009]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000436256	GTP_EFTU	PF00009.27	9.6e-47	1	1
ENSP00000434533	GTP_EFTU	PF00009.27	1.1e-46	1	1
ENSP00000356800	GTP_EFTU	PF00009.27	1.2e-46	1	1
ENSP00000389826	GTP_EFTU	PF00009.27	1.3e-46	1	1
ENSP00000356811	GTP_EFTU	PF00009.27	1.4e-46	1	1
ENSP00000436620	GTP_EFTU	PF00009.27	1.6e-38	1	1
ENSP00000432092	GTP_EFTU	PF00009.27	2.6e-09	1	1
ENSP00000436472	GTP_EFTU	PF00009.27	9.2e-08	1	1
ENSP00000356800	GTP_EFTU_D2	PF03144.25	9.7e-08	1	1
ENSP00000356811	GTP_EFTU_D2	PF03144.25	1.1e-07	1	1
ENSP00000436256	GTP_EFTU_D2	PF03144.25	1.5e-07	1	1
ENSP00000434533	GTP_EFTU_D2	PF03144.25	1.6e-07	1	1
ENSP00000389826	GTP_EFTU_D2	PF03144.25	2e-07	1	1
ENSP00000436256	GTP_EFTU_D3	PF03143.17	3.5e-31	1	1
ENSP00000389826	GTP_EFTU_D3	PF03143.17	3.9e-31	1	1
ENSP00000434533	GTP_EFTU_D3	PF03143.17	3.9e-31	1	1
ENSP00000356800	GTP_EFTU_D3	PF03143.17	5.3e-31	1	1
ENSP00000356811	GTP_EFTU_D3	PF03143.17	5.6e-31	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
24278036	Translation initiation factors eIF3 and HCR1 control translation termination and stop codon read-through in yeast cells.	PLoS Genet	2013 Nov	Beznoskova P	doi: 10.1371/journal.pgen.1003962

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000526100	HBS1L-209	1600	-	ENSP00000433161	74 (aa)	-	H0YD85
ENST00000415177	HBS1L-206	2636	-	ENSP00000389826	619 (aa)	-	J3QT46
ENST00000527578	HBS1L-212	2618	XM_024446308	ENSP00000436256	520 (aa)	XP_024302076	B7Z524
ENST00000367826	HBS1L-204	2703	-	ENSP00000356800	642 (aa)	-	Q9Y450
ENST00000367837	HBS1L-205	7163	-	ENSP00000356811	684 (aa)	-	Q9Y450
ENST00000525067	HBS1L-208	582	-	ENSP00000435608	118 (aa)	-	E9PJ90
ENST00000533274	HBS1L-216	2102	-	ENSP00000434533	554 (aa)	-	H0YDX7
ENST00000529169	HBS1L-213	633	-	ENSP00000436472	170 (aa)	-	H0YES5
ENST00000367822	HBS1L-203	2793	XM_017010192	ENSP00000356796	632 (aa)	XP_016865681	Q9Y450
ENST00000529882	HBS1L-215	544	-	ENSP00000433030	167 (aa)	-	E9PMN1
ENST00000527005	HBS1L-210	2224	-	-	- (aa)	-	-
ENST00000527507	HBS1L-211	629	-	ENSP00000432092	142 (aa)	-	E9PS53
ENST00000529641	HBS1L-214	881	-	ENSP00000436620	243 (aa)	-	E9PHZ9
ENST00000367820	HBS1L-202	638	-	ENSP00000356794	147 (aa)	-	G5E991
ENST00000314674	HBS1L-201	980	-	ENSP00000323566	215 (aa)	-	E9PLR4
ENST00000524715	HBS1L-207	551	-	ENSP00000434855	141 (aa)	-	E9PN23

Gene Model

Click here to download ENSG00000112339's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa03015	mRNA surveillance pathway	KEGG
hsa05134	Legionellosis	KEGG

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000112339	Fetal Hemoglobin	5.65e-005	-

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000112339	rs9376090	6	135090090	?	Platelet count	29066854	[4.76-9.83] unit increase	7.296	EFO_0004309
ENSG00000112339	rs9389248	6	134961518	C	High light scatter reticulocyte percentage of red cells	27863252	[0.031-0.045] unit increase	0.03820925	EFO_0007986
ENSG00000112339	rs7776054	6	135097778	G	Monocyte count	27863252	[0.032-0.048] unit decrease	0.04041738	EFO_0005091
ENSG00000112339	rs9402673	6	135001482	T	Reticulocyte count	27863252	[0.028-0.042] unit increase	0.03463692	EFO_0007986
ENSG00000112339	rs6904897	6	135061842	G	Mean corpuscular hemoglobin	27863252	[0.056-0.07] unit increase	0.06313863	EFO_0004527
ENSG00000112339	rs567333455	6	135094331	CA	Mean corpuscular hemoglobin	27863252	[0.12-0.14] unit decrease	0.1291719	EFO_0004527
ENSG00000112339	rs7776054	6	135097778	G	Mean corpuscular hemoglobin	27863252	[0.21-0.22] unit increase	0.2159334	EFO_0004527
ENSG00000112339	rs9399135	6	135047176	A	Red blood cell count	27863252	[0.028-0.042] unit decrease	0.03472818	EFO_0004305
ENSG00000112339	rs41294858	6	135091498	C	Red blood cell count	27863252	[0.12-0.15] unit increase	0.1341788	EFO_0004305
ENSG00000112339	rs7776054	6	135097778	G	Red blood cell count	27863252	[0.18-0.2] unit decrease	0.1877004	EFO_0004305
ENSG00000112339	rs6904897	6	135061842	G	Mean corpuscular volume	27863252	[0.05-0.064] unit increase	0.05672822	EFO_0004526
ENSG00000112339	rs2210366	6	135094070	A	Mean corpuscular volume	27863252	[0.12-0.13] unit decrease	0.125015	EFO_0004526
ENSG00000112339	rs7776054	6	135097778	G	Mean corpuscular volume	27863252	[0.2-0.21] unit increase	0.2032018	EFO_0004526
ENSG00000112339	rs7775698	6	135097497	T	Hematological and biochemical traits	20139978	[0.056-0.104] unit decrease	0.08	EFO_0004348
ENSG00000112339	rs7775698	6	135097497	T	Mean corpuscular hemoglobin	20139978	[0.19-0.23] unit increase	0.211	EFO_0004509\|EFO_0004527
ENSG00000112339	rs7775698	6	135097497	T	Mean corpuscular volume	20139978	[0.17-0.22] unit increase	0.194	EFO_0004526
ENSG00000112339	rs7775698	6	135097497	T	Platelet count	20139978	[0.069-0.117] unit increase	0.093	EFO_0004309
ENSG00000112339	rs7775698	6	135097497	T	Mean corpuscular hemoglobin concentration	20139978	[0.061-0.109] unit increase	0.085	EFO_0004509\|EFO_0004528
ENSG00000112339	rs7775698	6	135097497	T	Red blood cell count	20139978	[0.16-0.20] unit decrease	0.179	EFO_0004305
ENSG00000112339	rs7776054	6	135097778	?	Hematocrit	28017375			EFO_0004348
ENSG00000112339	rs7776054	6	135097778	?	Mean corpuscular volume	28017375			EFO_0004526
ENSG00000112339	rs9376090	6	135090090	T	Mean corpuscular hemoglobin concentration	28017375	[0.0013-0.0025] unit decrease	0.0019	EFO_0004528
ENSG00000112339	rs7776054	6	135097778	?	Mean corpuscular hemoglobin concentration	28017375			EFO_0004528
ENSG00000112339	rs7776054	6	135097778	G	Hemoglobin levels	26366553	[0.14-0.22] percentage increase	0.1762	EFO_0004509\|EFO_0005845
ENSG00000112339	rs9399137	6	135097880	C	Hemoglobin levels	26366553	[0.38-0.46] g/dl increase	0.4202	EFO_0004509\|EFO_0004576
ENSG00000112339	rs9399137	6	135097880	C	HbA2 levels	23043469			EFO_0005845
ENSG00000112339	rs9399137	6	135097880	T	Hematology traits	23263863	[0.021-0.051] unit increase	0.0361	EFO_0004305
ENSG00000112339	rs7775698	6	135097497	T	Mean corpuscular volume	23263863	[0.37-0.72] unit increase	0.5411	EFO_0004526
ENSG00000112339	rs9399137	6	135097880	T	Mean corpuscular volume	23263863	[0.39-0.71] unit decrease	0.5546	EFO_0004526
ENSG00000112339	rs7775698	6	135097497	T	Mean corpuscular hemoglobin	23263863	[0.19-0.32] unit increase	0.2534	EFO_0004527
ENSG00000112339	rs9399137	6	135097880	T	Mean corpuscular hemoglobin	23263863	[0.19-0.31] unit decrease	0.2519	EFO_0004527
ENSG00000112339	rs9399137	6	135097880	C	Platelet count	22139419	[5.1-6.7] 10^9/l increase	5.901	EFO_0004309
ENSG00000112339	rs9399137	6	135097880	T	Glycated hemoglobin levels	24647736	[0.050-0.090] unit increase	0.07	EFO_0004541
ENSG00000112339	rs7776054	6	135097778	G	Red blood cell traits	23935956	[0.0060-0.0146] unit increase	0.0103	EFO_0004527
ENSG00000112339	rs9399137	6	135097880	T	Platelet count	24026423	[NR] unit decrease	5.51	EFO_0004309
ENSG00000112339	rs7745098	6	135093866	G	Hodgkin's lymphoma	24149102	[1.14-1.29]	1.21	EFO_0000183
ENSG00000112339	rs9373124	6	135102071	C	Other erythrocyte phenotypes	19862010	[0.002-0.003] g/dl decrease	0	EFO_0004528
ENSG00000112339	rs7776054	6	135097778	G	Mean corpuscular hemoglobin	19862010	[0.009-0.0111] pg decrease	0.01	EFO_0004527
ENSG00000112339	rs7776054	6	135097778	?	Hemoglobin A1c levels	29403010	[0.049-0.077] unit decrease novel	0.06296	EFO_0004541
ENSG00000112339	rs9389268	6	135098493	?	Aspartate aminotransferase levels	29403010	[0.016-0.031] unit decrease novel	0.02333	EFO_0004736
ENSG00000112339	rs9399136	6	135081201	?	White blood cell count	29403010	[0.034-0.051] unit decrease novel	0.04238	EFO_0004308
ENSG00000112339	rs2210366	6	135094070	?	Eosinophil counts	29403010	[0.046-0.069] unit increase novel	0.05751	EFO_0004842
ENSG00000112339	rs9376090	6	135090090	?	Red blood cell count	29403010	[0.13-0.15] unit decrease novel	0.1404	EFO_0004305
ENSG00000112339	rs35367489	6	135023317	?	Red blood cell count	29403010	[0.033-0.051] unit increase novel	0.042022318	EFO_0004305
ENSG00000112339	rs9399136	6	135081201	?	Hemoglobin	29403010	[0.029-0.047] unit decrease novel	0.03809	EFO_0004509
ENSG00000112339	rs1331309	6	135085040	?	Hematocrit	29403010	[0.055-0.072] unit decrease novel	0.06368	EFO_0004348
ENSG00000112339	rs9399137	6	135097880	?	Mean corpuscular volume	29403010	[0.16-0.18] unit increase novel	0.1718	EFO_0004526
ENSG00000112339	rs12664956	6	135063050	?	Mean corpuscular volume	29403010	[0.042-0.06] unit decrease novel	0.050826687	EFO_0004526
ENSG00000112339	rs7776054	6	135097778	?	Mean corpuscular hemoglobin	29403010	[0.18-0.19] unit increase novel	0.1861	EFO_0004527
ENSG00000112339	rs12664956	6	135063050	?	Mean corpuscular hemoglobin	29403010	[0.044-0.062] unit decrease novel	0.052767143	EFO_0004527
ENSG00000112339	rs7776054	6	135097778	?	Mean corpuscular hemoglobin concentration	29403010	[0.071-0.089] unit increase novel	0.07997	EFO_0004528
ENSG00000112339	rs4896131	6	135070962	?	Mean corpuscular hemoglobin concentration	29403010	[0.016-0.034] unit decrease novel	0.02504868	EFO_0004528
ENSG00000112339	rs9399137	6	135097880	?	Platelet count	29403010	[0.096-0.114] unit increase novel	0.1049	EFO_0004309
ENSG00000112339	rs11757577	6	135070327	?	Platelet count	29403010	[0.015-0.032] unit increase novel	0.02309	EFO_0004309
ENSG00000112339	rs9389268	6	135098493	A	Mean corpuscular hemoglobin	28453575	[0.14-0.30] pg decrease	0.22	EFO_0004527
ENSG00000112339	rs9376090	6	135090090	C	Hematocrit	27863252	[0.072-0.088] unit decrease	0.0803522	EFO_0004348
ENSG00000112339	rs9376090	6	135090090	C	Hemoglobin concentration	27863252	[0.042-0.058] unit decrease	0.04957227	EFO_0004509
ENSG00000112339	rs34208856	6	135099930	C	Myeloid white cell count	27863252	[0.031-0.047] unit decrease	0.0386862	EFO_0007988
ENSG00000112339	rs34164109	6	135100038	T	Reticulocyte fraction of red cells	27863252	[0.041-0.058] unit increase	0.04989433	EFO_0007986
ENSG00000112339	rs1331308	6	135083984	C	Platelet count	27863252	[0.026-0.04] unit increase	0.0330161	EFO_0004309
ENSG00000112339	rs7776054	6	135097778	G	Platelet count	27863252	[0.11-0.13] unit increase	0.1191713	EFO_0004309
ENSG00000112339	rs530424960	6	135028265	TA	Red cell distribution width	27863252	[0.025-0.039] unit decrease	0.03181189	EFO_0005192
ENSG00000112339	rs7776054	6	135097778	G	Red cell distribution width	27863252	[0.087-0.103] unit decrease	0.09491537	EFO_0005192
ENSG00000112339	rs34208856	6	135099930	C	White blood cell count	27863252	[0.04-0.056] unit decrease	0.04813201	EFO_0004308
ENSG00000112339	rs9402673	6	135001482	T	High light scatter reticulocyte count	27863252	[0.026-0.04] unit increase	0.03313665	EFO_0007986
ENSG00000112339	rs4896131	6	135070962	A	Mean corpuscular hemoglobin concentration	27863252	[0.014-0.028] unit increase	0.02082222	EFO_0004528
ENSG00000112339	rs7776054	6	135097778	G	Mean corpuscular hemoglobin concentration	27863252	[0.084-0.099] unit increase	0.09130758	EFO_0004528
ENSG00000112339	rs34208856	6	135099930	C	Neutrophil count	27863252	[0.026-0.042] unit decrease	0.03393884	EFO_0004833
ENSG00000112339	rs9402682	6	135085045	T	Neutrophil percentage of granulocytes	27863252	[0.028-0.045] unit decrease	0.03658366	EFO_0007994
ENSG00000112339	rs4580893	6	134976524	A	Plateletcrit	27863252	[0.033-0.048] unit increase	0.04043883	EFO_0007985
ENSG00000112339	rs1331308	6	135083984	C	Plateletcrit	27863252	[0.03-0.044] unit increase	0.03678186	EFO_0007985
ENSG00000112339	rs7776054	6	135097778	G	Plateletcrit	27863252	[0.13-0.14] unit increase	0.1357089	EFO_0007985
ENSG00000112339	rs34164109	6	135100038	C	Red blood cell count	28453575	[0.034-0.074] cells x E9 increase	0.054	EFO_0004305
ENSG00000112339	rs9389268	6	135098493	A	Mean corpuscular volume	28453575	[0.38-0.78] fL decrease	0.58	EFO_0004526
ENSG00000112339	rs7775698	6	135097497	C	Hematology traits	19853236	[0.15-0.23] s.d. decrease	0.19	EFO_0004526
ENSG00000112339	rs7775698	6	135097497	C	Hematology traits	19853236	[0.13-0.25] s.d. decrease	0.19	EFO_0004527
ENSG00000112339	rs9399137	6	135097880	T	Hematology traits	19853236	[0.10-0.22] s.d. decrease	0.16	EFO_0004309
ENSG00000112339	rs7775698	6	135097497	T	Red blood cell traits	20927387	[0.07-0.11] unit decrease	0.09	EFO_0004305
ENSG00000112339	rs7775698	6	135097497	T	Red blood cell traits	20927387	[0.29-0.47] unit increase	0.38	EFO_0004527
ENSG00000112339	rs9399137	6	135097880	?	F-cell distribution	17767159	[NR] % variance	15.8	EFO_0004576
ENSG00000112339	rs9373124	6	135102071	T	White blood cell types	21738478	[0.06-0.10] unit increase	0.08	EFO_0004842
ENSG00000112339	rs9402682	6	135085045	T	Eosinophil percentage of granulocytes	27863252	[0.027-0.043] unit increase	0.03517155	EFO_0007996
ENSG00000112339	rs34208856	6	135099930	C	Granulocyte count	27863252	[0.028-0.044] unit decrease	0.03593464	EFO_0007987
ENSG00000112339	rs1331309	6	135085040	G	Mean corpuscular hemoglobin	28548082	[0.14-0.27] unit increase	0.201	EFO_0004527
ENSG00000112339	rs9402682	6	135085045	T	Sum eosinophil basophil counts	27863252	[0.032-0.049] unit increase	0.04025881	EFO_0005090\|EFO_0004842
ENSG00000112339	rs34208856	6	135099930	C	Sum neutrophil eosinophil counts	27863252	[0.028-0.044] unit decrease	0.03624577	EFO_0004833\|EFO_0004842
ENSG00000112339	rs34208856	6	135099930	C	Sum basophil neutrophil counts	27863252	[0.026-0.042] unit decrease	0.03364815	EFO_0004833\|EFO_0005090
ENSG00000112339	rs9402682	6	135085045	T	Eosinophil percentage of white cells	27863252	[0.027-0.043] unit increase	0.03514971	EFO_0007991
ENSG00000112339	rs9402682	6	135085045	T	Eosinophil counts	27863252	[0.03-0.047] unit increase	0.03827879	EFO_0004842
ENSG00000112339	rs35959442	6	135103041	G	Eosinophil counts	27863252	[0.029-0.044] unit decrease	0.0366371	EFO_0004842
ENSG00000112339	rs7775698	6	135097497	T	LDL cholesterol levels	28334899	[0.042-0.086] unit decrease	0.064	EFO_0004611
ENSG00000112339	rs7776054	6	135097778	A	LDL cholesterol levels	28334899	[0.033-0.069] unit increase	0.051	EFO_0004611
ENSG00000112339	rs7775698	6	135097497	T	Total cholesterol levels	28334899	[0.055-0.099] unit decrease	0.077	EFO_0004574
ENSG00000112339	rs9376090	6	135090090	T	Total cholesterol levels	28334899	[0.018-0.033] unit increase (EA Beta values)	0.0254	EFO_0004574
ENSG00000112339	rs7775698	6	135097497	T	Total cholesterol levels	28334899	[0.055-0.099] unit decrease	0.077	EFO_0004574
ENSG00000112339	rs7775698	6	135097497	T	Red cell distribution width	28957414	[0.088-0.105] unit decrease	0.0966506	EFO_0005192
ENSG00000112339	rs9376090	6	135090090	T	Low density lipoprotein cholesterol levels	29507422	unit increase	0.041	EFO_0004611
ENSG00000112339	rs9376090	6	135090090	T	Low density lipoprotein cholesterol levels	29507422	unit increase	0.038	EFO_0004611
ENSG00000112339	rs35786788	6	135097904	G	Low density lipoprotein cholesterol levels	29507422	unit increase	0.041	EFO_0004611
ENSG00000112339	rs35786788	6	135097904	G	Low density lipoprotein cholesterol levels	29507422	unit increase	0.038	EFO_0004611
ENSG00000112339	rs9376090	6	135090090	T	Total cholesterol levels	29507422	unit increase	0.043	EFO_0004574
ENSG00000112339	rs9376090	6	135090090	T	Total cholesterol levels	29507422	unit increase	0.04	EFO_0004574
ENSG00000112339	rs35786788	6	135097904	G	Total cholesterol levels	29507422	unit increase	0.043	EFO_0004574
ENSG00000112339	rs35786788	6	135097904	G	Total cholesterol levels	29507422	unit increase	0.041	EFO_0004574
ENSG00000112339	rs9399136	6	135081201	?	Red cell distribution width	30595370			EFO_0005192
ENSG00000112339	rs9376091	6	135098498	?	White blood cell count	30595370			EFO_0004308
ENSG00000112339	rs1547247	6	135069698	?	Red blood cell count	30595370			EFO_0004305
ENSG00000112339	rs56131511	6	135068381	?	Eosinophil counts	30595370			EFO_0004842
ENSG00000112339	rs148394396	6	135022389	?	Mean corpuscular hemoglobin	30595370			EFO_0004527

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000112339's network

* RBP PPI network refers to all genes directly bind to RBP

Paralogs

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy
ENSG00000112339	HBS1L	99	36.313	ENSG00000101210	EEF1A2	97	60.811
ENSG00000112339	HBS1L	94	42.945	ENSG00000189369	GSPT2	75	40.292
ENSG00000112339	HBS1L	95	42.683	ENSG00000103342	GSPT1	85	42.991
ENSG00000112339	HBS1L	99	36.872	ENSG00000156508	EEF1A1	97	59.574

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000112339	HBS1L	95	82.609	ENSAPOG00000013169	hbs1l	91	84.718	Acanthochromis_polyacanthus
ENSG00000112339	HBS1L	99	94.220	ENSAMEG00000009749	HBS1L	99	92.690	Ailuropoda_melanoleuca
ENSG00000112339	HBS1L	95	85.093	ENSACIG00000017087	hbs1l	91	77.778	Amphilophus_citrinellus
ENSG00000112339	HBS1L	100	78.654	ENSAPEG00000008320	hbs1l	100	71.286	Amphiprion_percula
ENSG00000112339	HBS1L	100	79.808	ENSATEG00000004459	hbs1l	100	71.791	Anabas_testudineus
ENSG00000112339	HBS1L	100	86.538	ENSAPLG00000007791	HBS1L	100	80.650	Anas_platyrhynchos
ENSG00000112339	HBS1L	100	85.962	ENSACAG00000010120	HBS1L	100	81.395	Anolis_carolinensis
ENSG00000112339	HBS1L	100	97.500	ENSANAG00000038076	HBS1L	100	96.642	Aotus_nancymaae
ENSG00000112339	HBS1L	95	86.335	ENSACLG00000010469	hbs1l	100	71.994	Astatotilapia_calliptera
ENSG00000112339	HBS1L	95	86.957	ENSAMXG00000004260	hbs1l	97	77.321	Astyanax_mexicanus
ENSG00000112339	HBS1L	100	94.242	ENSBTAG00000020174	HBS1L	100	92.566	Bos_taurus
ENSG00000112339	HBS1L	91	51.613	WBGene00010622	K07A12.4	99	40.845	Caenorhabditis_elegans
ENSG00000112339	HBS1L	100	97.500	ENSCJAG00000007678	HBS1L	100	96.934	Callithrix_jacchus
ENSG00000112339	HBS1L	100	94.050	ENSCAFG00000000226	HBS1L	100	91.691	Canis_familiaris
ENSG00000112339	HBS1L	100	94.050	ENSCAFG00020021904	HBS1L	100	91.691	Canis_lupus_dingo
ENSG00000112339	HBS1L	100	93.474	ENSCHIG00000010299	HBS1L	100	91.691	Capra_hircus
ENSG00000112339	HBS1L	100	95.202	ENSTSYG00000007089	HBS1L	100	93.720	Carlito_syrichta
ENSG00000112339	HBS1L	95	93.789	ENSCPOG00000007015	HBS1L	99	78.655	Cavia_porcellus
ENSG00000112339	HBS1L	100	97.121	ENSCCAG00000033863	HBS1L	100	96.321	Cebus_capucinus
ENSG00000112339	HBS1L	100	98.269	ENSCATG00000043042	HBS1L	100	97.953	Cercocebus_atys
ENSG00000112339	HBS1L	100	92.706	ENSCLAG00000004937	HBS1L	100	90.816	Chinchilla_lanigera
ENSG00000112339	HBS1L	100	97.942	ENSCSAG00000016791	HBS1L	100	97.664	Chlorocebus_sabaeus
ENSG00000112339	HBS1L	97	91.304	ENSCHOG00000001852	HBS1L	97	91.304	Choloepus_hoffmanni
ENSG00000112339	HBS1L	100	88.462	ENSCPBG00000017635	HBS1L	100	84.425	Chrysemys_picta_bellii
ENSG00000112339	HBS1L	96	56.707	ENSCING00000005592	-	99	48.527	Ciona_intestinalis
ENSG00000112339	HBS1L	95	59.627	ENSCSAVG00000002297	-	99	60.741	Ciona_savignyi
ENSG00000112339	HBS1L	100	97.885	ENSCANG00000031208	HBS1L	100	97.664	Colobus_angolensis_palliatus
ENSG00000112339	HBS1L	100	93.295	ENSCGRG00001024531	Hbs1l	100	90.525	Cricetulus_griseus_chok1gshd
ENSG00000112339	HBS1L	100	93.295	ENSCGRG00000017361	Hbs1l	100	90.525	Cricetulus_griseus_crigri
ENSG00000112339	HBS1L	95	86.957	ENSCSEG00000002794	hbs1l	94	75.975	Cynoglossus_semilaevis
ENSG00000112339	HBS1L	95	86.335	ENSCVAG00000001462	hbs1l	100	71.489	Cyprinodon_variegatus
ENSG00000112339	HBS1L	100	91.304	ENSDARG00000036778	hbs1l	100	72.150	Danio_rerio
ENSG00000112339	HBS1L	100	93.090	ENSDORG00000005958	Hbs1l	100	90.949	Dipodomys_ordii
ENSG00000112339	HBS1L	97	55.138	FBgn0042712	HBS1	100	48.080	Drosophila_melanogaster
ENSG00000112339	HBS1L	95	93.789	ENSETEG00000000913	HBS1L	100	86.277	Echinops_telfairi
ENSG00000112339	HBS1L	100	70.518	ENSEBUG00000010759	hbs1l	100	66.007	Eptatretus_burgeri
ENSG00000112339	HBS1L	100	92.912	ENSEASG00005011148	HBS1L	100	90.975	Equus_asinus_asinus
ENSG00000112339	HBS1L	100	93.487	ENSECAG00000004470	HBS1L	100	91.925	Equus_caballus
ENSG00000112339	HBS1L	100	93.295	ENSEEUG00000013582	HBS1L	100	86.006	Erinaceus_europaeus
ENSG00000112339	HBS1L	92	87.821	ENSELUG00000006444	hbs1l	99	66.003	Esox_lucius
ENSG00000112339	HBS1L	100	94.818	ENSFCAG00000001810	HBS1L	100	94.818	Felis_catus
ENSG00000112339	HBS1L	100	86.731	ENSFALG00000011898	HBS1L	100	82.245	Ficedula_albicollis
ENSG00000112339	HBS1L	100	93.090	ENSFDAG00000011841	HBS1L	100	90.816	Fukomys_damarensis
ENSG00000112339	HBS1L	95	86.957	ENSFHEG00000006942	hbs1l	100	71.773	Fundulus_heteroclitus
ENSG00000112339	HBS1L	95	86.957	ENSGMOG00000011843	hbs1l	100	72.555	Gadus_morhua
ENSG00000112339	HBS1L	100	86.923	ENSGALG00000013962	HBS1L	100	81.831	Gallus_gallus
ENSG00000112339	HBS1L	95	86.335	ENSGAFG00000004157	hbs1l	100	72.624	Gambusia_affinis
ENSG00000112339	HBS1L	95	84.472	ENSGACG00000011035	hbs1l	100	71.698	Gasterosteus_aculeatus
ENSG00000112339	HBS1L	100	88.077	ENSGAGG00000002033	HBS1L	100	83.721	Gopherus_agassizii
ENSG00000112339	HBS1L	100	100.000	ENSGGOG00000034956	-	98	94.649	Gorilla_gorilla
ENSG00000112339	HBS1L	95	86.335	ENSHBUG00000013424	hbs1l	100	72.136	Haplochromis_burtoni
ENSG00000112339	HBS1L	100	92.500	ENSHGLG00000000516	HBS1L	100	90.511	Heterocephalus_glaber_female
ENSG00000112339	HBS1L	100	92.500	ENSHGLG00100003550	HBS1L	100	90.511	Heterocephalus_glaber_male
ENSG00000112339	HBS1L	100	89.362	ENSHCOG00000007581	hbs1l	94	71.676	Hippocampus_comes
ENSG00000112339	HBS1L	95	84.472	ENSIPUG00000010748	hbs1l	100	72.384	Ictalurus_punctatus
ENSG00000112339	HBS1L	100	95.010	ENSSTOG00000007551	HBS1L	100	93.157	Ictidomys_tridecemlineatus
ENSG00000112339	HBS1L	99	90.559	ENSJJAG00000017024	-	97	86.384	Jaculus_jaculus
ENSG00000112339	HBS1L	99	81.743	ENSJJAG00000012660	-	100	74.684	Jaculus_jaculus
ENSG00000112339	HBS1L	100	80.192	ENSKMAG00000012130	hbs1l	99	77.615	Kryptolebias_marmoratus
ENSG00000112339	HBS1L	95	85.714	ENSLBEG00000002784	hbs1l	100	77.258	Labrus_bergylta
ENSG00000112339	HBS1L	100	79.098	ENSLACG00000004528	HBS1L	100	79.150	Latimeria_chalumnae
ENSG00000112339	HBS1L	100	81.766	ENSLOCG00000016221	hbs1l	100	73.315	Lepisosteus_oculatus
ENSG00000112339	HBS1L	100	92.529	ENSLAFG00000007835	HBS1L	100	90.830	Loxodonta_africana
ENSG00000112339	HBS1L	100	98.384	ENSMFAG00000003766	HBS1L	100	98.384	Macaca_fascicularis
ENSG00000112339	HBS1L	100	98.384	ENSMMUG00000004802	HBS1L	100	98.384	Macaca_mulatta
ENSG00000112339	HBS1L	100	98.384	ENSMNEG00000043942	HBS1L	100	98.384	Macaca_nemestrina
ENSG00000112339	HBS1L	100	98.077	ENSMLEG00000043218	HBS1L	100	97.508	Mandrillus_leucophaeus
ENSG00000112339	HBS1L	95	85.093	ENSMAMG00000016498	hbs1l	98	78.333	Mastacembelus_armatus
ENSG00000112339	HBS1L	95	86.335	ENSMZEG00005024018	-	91	77.697	Maylandia_zebra
ENSG00000112339	HBS1L	95	86.335	ENSMZEG00005015575	hbs1l	100	71.994	Maylandia_zebra
ENSG00000112339	HBS1L	100	86.346	ENSMGAG00000013065	HBS1L	99	80.234	Meleagris_gallopavo
ENSG00000112339	HBS1L	100	93.282	ENSMAUG00000001077	Hbs1l	100	90.657	Mesocricetus_auratus
ENSG00000112339	HBS1L	99	94.027	ENSMICG00000001533	-	99	93.136	Microcebus_murinus
ENSG00000112339	HBS1L	99	90.780	ENSMICG00000030043	-	96	94.086	Microcebus_murinus
ENSG00000112339	HBS1L	100	93.103	ENSMOCG00000023038	Hbs1l	100	90.233	Microtus_ochrogaster
ENSG00000112339	HBS1L	95	87.578	ENSMMOG00000015507	hbs1l	100	71.742	Mola_mola
ENSG00000112339	HBS1L	100	90.595	ENSMODG00000017499	HBS1L	100	87.627	Monodelphis_domestica
ENSG00000112339	HBS1L	95	85.093	ENSMALG00000010768	hbs1l	99	76.129	Monopterus_albus
ENSG00000112339	HBS1L	100	91.571	MGP_CAROLIEiJ_G0015162	Hbs1l	100	88.630	Mus_caroli
ENSG00000112339	HBS1L	100	91.571	ENSMUSG00000019977	Hbs1l	100	100.000	Mus_musculus
ENSG00000112339	HBS1L	100	89.847	MGP_PahariEiJ_G0023782	Hbs1l	100	87.172	Mus_pahari
ENSG00000112339	HBS1L	100	91.571	MGP_SPRETEiJ_G0015970	Hbs1l	100	88.776	Mus_spretus
ENSG00000112339	HBS1L	100	94.818	ENSMPUG00000014810	HBS1L	100	92.711	Mustela_putorius_furo
ENSG00000112339	HBS1L	100	95.010	ENSMLUG00000010618	HBS1L	100	93.577	Myotis_lucifugus
ENSG00000112339	HBS1L	100	93.090	ENSNGAG00000015184	Hbs1l	100	89.635	Nannospalax_galili
ENSG00000112339	HBS1L	95	86.335	ENSNBRG00000020095	hbs1l	99	78.889	Neolamprologus_brichardi
ENSG00000112339	HBS1L	100	98.462	ENSNLEG00000014721	HBS1L	100	98.442	Nomascus_leucogenys
ENSG00000112339	HBS1L	100	76.224	ENSMEUG00000003907	HBS1L	81	93.909	Notamacropus_eugenii
ENSG00000112339	HBS1L	85	95.868	ENSOPRG00000013595	HBS1L	76	95.868	Ochotona_princeps
ENSG00000112339	HBS1L	100	92.692	ENSODEG00000008959	HBS1L	100	89.851	Octodon_degus
ENSG00000112339	HBS1L	95	86.957	ENSONIG00000000460	hbs1l	100	72.051	Oreochromis_niloticus
ENSG00000112339	HBS1L	99	86.372	ENSOANG00000002684	-	99	84.012	Ornithorhynchus_anatinus
ENSG00000112339	HBS1L	95	96.273	ENSOCUG00000011619	HBS1L	99	91.196	Oryctolagus_cuniculus
ENSG00000112339	HBS1L	95	85.714	ENSORLG00000016559	hbs1l	100	70.763	Oryzias_latipes
ENSG00000112339	HBS1L	95	85.714	ENSORLG00020003827	hbs1l	100	70.621	Oryzias_latipes_hni
ENSG00000112339	HBS1L	95	85.093	ENSORLG00015023105	hbs1l	100	70.480	Oryzias_latipes_hsok
ENSG00000112339	HBS1L	95	87.578	ENSOMEG00000016715	hbs1l	100	71.915	Oryzias_melastigma
ENSG00000112339	HBS1L	100	95.000	ENSOGAG00000012604	HBS1L	100	93.860	Otolemur_garnettii
ENSG00000112339	HBS1L	100	93.282	ENSOARG00000005671	-	100	91.545	Ovis_aries
ENSG00000112339	HBS1L	99	93.642	ENSOARG00000014798	-	99	91.959	Ovis_aries
ENSG00000112339	HBS1L	100	100.000	ENSPPAG00000029900	HBS1L	100	99.708	Pan_paniscus
ENSG00000112339	HBS1L	100	95.010	ENSPPRG00000005285	HBS1L	100	94.686	Panthera_pardus
ENSG00000112339	HBS1L	100	94.818	ENSPTIG00000015803	HBS1L	100	94.525	Panthera_tigris_altaica
ENSG00000112339	HBS1L	100	100.000	ENSPTRG00000018630	HBS1L	100	99.708	Pan_troglodytes
ENSG00000112339	HBS1L	100	97.942	ENSPANG00000007075	HBS1L	100	97.807	Papio_anubis
ENSG00000112339	HBS1L	100	77.692	ENSPKIG00000023171	hbs1l	100	71.739	Paramormyrops_kingsleyae
ENSG00000112339	HBS1L	100	83.951	ENSPSIG00000016467	HBS1L	97	80.944	Pelodiscus_sinensis
ENSG00000112339	HBS1L	95	85.093	ENSPMGG00000018051	hbs1l	96	85.106	Periophthalmus_magnuspinnatus
ENSG00000112339	HBS1L	100	92.720	ENSPEMG00000014369	Hbs1l	100	89.796	Peromyscus_maniculatus_bairdii
ENSG00000112339	HBS1L	94	82.609	ENSPMAG00000002516	hbs1l	100	66.328	Petromyzon_marinus
ENSG00000112339	HBS1L	95	85.093	ENSPFOG00000021764	hbs1l	100	71.853	Poecilia_formosa
ENSG00000112339	HBS1L	95	85.093	ENSPLAG00000006193	hbs1l	100	72.199	Poecilia_latipinna
ENSG00000112339	HBS1L	95	89.130	ENSPMEG00000000925	hbs1l	100	72.199	Poecilia_mexicana
ENSG00000112339	HBS1L	95	89.130	ENSPREG00000011270	hbs1l	100	71.773	Poecilia_reticulata
ENSG00000112339	HBS1L	100	99.588	ENSPPYG00000017027	HBS1L	100	98.977	Pongo_abelii
ENSG00000112339	HBS1L	100	93.666	ENSPCAG00000007002	HBS1L	90	93.161	Procavia_capensis
ENSG00000112339	HBS1L	100	94.239	ENSPVAG00000015229	HBS1L	90	91.852	Pteropus_vampyrus
ENSG00000112339	HBS1L	95	86.335	ENSPNYG00000013360	hbs1l	100	71.994	Pundamilia_nyererei
ENSG00000112339	HBS1L	93	89.130	ENSPNAG00000026721	hbs1l	100	73.631	Pygocentrus_nattereri
ENSG00000112339	HBS1L	100	91.379	ENSRNOG00000014531	Hbs1l	100	88.484	Rattus_norvegicus
ENSG00000112339	HBS1L	100	98.765	ENSRBIG00000004484	HBS1L	100	98.246	Rhinopithecus_bieti
ENSG00000112339	HBS1L	100	98.765	ENSRROG00000026176	HBS1L	100	98.099	Rhinopithecus_roxellana
ENSG00000112339	HBS1L	92	36.747	YKR084C	-	73	38.876	Saccharomyces_cerevisiae
ENSG00000112339	HBS1L	100	87.413	ENSSBOG00000016930	-	98	89.362	Saimiri_boliviensis_boliviensis
ENSG00000112339	HBS1L	100	96.545	ENSSBOG00000019696	-	100	96.204	Saimiri_boliviensis_boliviensis
ENSG00000112339	HBS1L	100	92.514	ENSSHAG00000013509	HBS1L	100	89.374	Sarcophilus_harrisii
ENSG00000112339	HBS1L	95	81.988	ENSSFOG00015017544	hbs1l	96	71.179	Scleropages_formosus
ENSG00000112339	HBS1L	95	83.851	ENSSMAG00000010621	hbs1l	100	70.822	Scophthalmus_maximus
ENSG00000112339	HBS1L	95	86.335	ENSSDUG00000012974	hbs1l	100	72.096	Seriola_dumerili
ENSG00000112339	HBS1L	95	86.335	ENSSLDG00000004960	hbs1l	99	77.716	Seriola_lalandi_dorsalis
ENSG00000112339	HBS1L	100	92.885	ENSSARG00000006747	HBS1L	100	90.135	Sorex_araneus
ENSG00000112339	HBS1L	99	84.749	ENSSPUG00000012389	HBS1L	99	81.022	Sphenodon_punctatus
ENSG00000112339	HBS1L	100	92.623	ENSSSCG00000004169	HBS1L	100	92.598	Sus_scrofa
ENSG00000112339	HBS1L	99	86.127	ENSTGUG00000011507	HBS1L	99	80.204	Taeniopygia_guttata
ENSG00000112339	HBS1L	94	85.106	ENSTRUG00000016128	hbs1l	90	86.486	Takifugu_rubripes
ENSG00000112339	HBS1L	95	85.714	ENSTNIG00000016320	hbs1l	99	73.692	Tetraodon_nigroviridis
ENSG00000112339	HBS1L	100	100.000	ENSTBEG00000009950	HBS1L	92	100.000	Tupaia_belangeri
ENSG00000112339	HBS1L	99	93.846	ENSTTRG00000003715	HBS1L	99	91.971	Tursiops_truncatus
ENSG00000112339	HBS1L	100	94.818	ENSUAMG00000001064	HBS1L	100	93.149	Ursus_americanus
ENSG00000112339	HBS1L	100	94.626	ENSUMAG00000024395	HBS1L	100	97.297	Ursus_maritimus
ENSG00000112339	HBS1L	100	93.474	ENSVPAG00000006280	HBS1L	90	92.976	Vicugna_pacos
ENSG00000112339	HBS1L	100	94.242	ENSVVUG00000000295	HBS1L	100	91.837	Vulpes_vulpes
ENSG00000112339	HBS1L	100	81.346	ENSXETG00000003726	hbs1l	100	75.620	Xenopus_tropicalis
ENSG00000112339	HBS1L	95	86.335	ENSXCOG00000005323	hbs1l	100	73.723	Xiphophorus_couchianus
ENSG00000112339	HBS1L	95	89.130	ENSXMAG00000004359	hbs1l	100	72.624	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0003746	translation elongation factor activity	-	IEA	Function
GO:0003924	GTPase activity	21873635.	IBA	Function
GO:0005525	GTP binding	-	IEA	Function
GO:0005829	cytosol	-	TAS	Component
GO:0006412	translation	21873635.	IBA	Process
GO:0006414	translational elongation	-	IEA	Process
GO:0007165	signal transduction	9872408.	TAS	Process
GO:0016020	membrane	19946888.	HDA	Component
GO:0043928	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay	-	TAS	Process
GO:0070062	extracellular exosome	19056867.	HDA	Component