EuRBPDB

Basic Information
Cancer Related Information

Description

RBDs

RBPome

Expression

Transcripts

Gene Model

Phenotypes

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000112996 (Gene tree)
Gene ID: 10884
Gene Symbol: MRPS30
Alias: PAP|PDCD9
Full Name: mitochondrial ribosomal protein S30
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Plus strand
Length: 11,504 bases
Position: chr5:44,808,925-44,820,428
Accession: 8769
RBP type: canonical RBP
Summary: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that is similar to the chicken pro-apoptotic protein p52. Transcript variants using alternative promoters or polyA sites have been mentioned in the literature but the complete description of these sequences is not available. [provided by RefSeq, Jul 2008]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000424328	PDCD9	PF07147.12	3e-185	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
22658674	Insights into RNA biology from an atlas of mammalian mRNA-binding proteins	RIC & Hela	2012 May 31	Castello A	DOI: 10.1016/j.cell.2012.04.031
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000230914	MRPS30-201	4331	-	-	- (aa)	-	-
ENST00000508129	MRPS30-203	560	-	-	- (aa)	-	-
ENST00000515647	MRPS30-204	733	-	-	- (aa)	-	-
ENST00000507110	MRPS30-202	1678	-	ENSP00000424328	439 (aa)	-	Q9NP92

Gene Model

Click here to download ENSG00000112996's gene model file

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000112996	Reproductive Behavior	4E-8	27798627
ENSG00000112996	Reproductive Behavior	2E-10	27798627
ENSG00000112996	Schizophrenia	1E-6	26198764
ENSG00000112996	Renal Insufficiency, Chronic	9E-6	20686651
ENSG00000112996	Breast Neoplasms	7E-7	20872241
ENSG00000112996	Education	2E-10	27225129

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000112996's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000112996	MRPS30	97	49.345	ENSAPOG00000005833	mrps30	81	51.629	Acanthochromis_polyacanthus
ENSG00000112996	MRPS30	100	79.499	ENSAMEG00000000569	MRPS30	100	79.271	Ailuropoda_melanoleuca
ENSG00000112996	MRPS30	88	52.806	ENSACIG00000024177	mrps30	92	52.972	Amphilophus_citrinellus
ENSG00000112996	MRPS30	95	50.583	ENSAOCG00000018917	mrps30	92	51.500	Amphiprion_ocellaris
ENSG00000112996	MRPS30	95	50.583	ENSAPEG00000012822	mrps30	85	51.500	Amphiprion_percula
ENSG00000112996	MRPS30	95	49.299	ENSATEG00000001216	mrps30	92	50.627	Anabas_testudineus
ENSG00000112996	MRPS30	98	63.510	ENSACAG00000011165	MRPS30	96	62.989	Anolis_carolinensis
ENSG00000112996	MRPS30	100	89.749	ENSANAG00000036508	MRPS30	100	89.522	Aotus_nancymaae
ENSG00000112996	MRPS30	88	52.956	ENSACLG00000020138	mrps30	92	52.320	Astatotilapia_calliptera
ENSG00000112996	MRPS30	88	55.128	ENSAMXG00000016126	mrps30	91	54.660	Astyanax_mexicanus
ENSG00000112996	MRPS30	100	80.410	ENSBTAG00000000084	MRPS30	100	80.410	Bos_taurus
ENSG00000112996	MRPS30	100	90.661	ENSCJAG00000040653	MRPS30	100	89.749	Callithrix_jacchus
ENSG00000112996	MRPS30	99	80.600	ENSCAFG00000018516	MRPS30	100	79.908	Canis_familiaris
ENSG00000112996	MRPS30	99	81.062	ENSCAFG00020023088	MRPS30	100	80.139	Canis_lupus_dingo
ENSG00000112996	MRPS30	100	81.549	ENSCHIG00000018591	MRPS30	100	81.549	Capra_hircus
ENSG00000112996	MRPS30	100	82.045	ENSTSYG00000009384	MRPS30	100	82.500	Carlito_syrichta
ENSG00000112996	MRPS30	100	79.043	ENSCPOG00000002067	MRPS30	100	79.043	Cavia_porcellus
ENSG00000112996	MRPS30	100	91.344	ENSCCAG00000019340	MRPS30	100	90.433	Cebus_capucinus
ENSG00000112996	MRPS30	100	96.128	ENSCATG00000044059	MRPS30	100	96.128	Cercocebus_atys
ENSG00000112996	MRPS30	100	72.665	ENSCLAG00000007412	MRPS30	100	71.202	Chinchilla_lanigera
ENSG00000112996	MRPS30	100	95.672	ENSCSAG00000016737	MRPS30	100	95.672	Chlorocebus_sabaeus
ENSG00000112996	MRPS30	100	66.743	ENSCHOG00000005579	MRPS30	100	66.743	Choloepus_hoffmanni
ENSG00000112996	MRPS30	98	63.573	ENSCPBG00000007637	MRPS30	99	64.037	Chrysemys_picta_bellii
ENSG00000112996	MRPS30	66	31.269	ENSCSAVG00000002974	-	78	31.269	Ciona_savignyi
ENSG00000112996	MRPS30	100	94.305	ENSCANG00000034816	MRPS30	100	94.761	Colobus_angolensis_palliatus
ENSG00000112996	MRPS30	99	75.744	ENSCGRG00001003133	Mrps30	97	75.744	Cricetulus_griseus_chok1gshd
ENSG00000112996	MRPS30	82	76.667	ENSCGRG00000012001	Mrps30	94	74.536	Cricetulus_griseus_crigri
ENSG00000112996	MRPS30	95	48.372	ENSCSEG00000018816	mrps30	93	49.127	Cynoglossus_semilaevis
ENSG00000112996	MRPS30	95	48.104	ENSCVAG00000015707	mrps30	93	49.000	Cyprinodon_variegatus
ENSG00000112996	MRPS30	90	51.759	ENSDARG00000104111	mrps30	94	51.759	Danio_rerio
ENSG00000112996	MRPS30	100	81.549	ENSDNOG00000006691	MRPS30	100	81.549	Dasypus_novemcinctus
ENSG00000112996	MRPS30	100	79.954	ENSDORG00000014828	Mrps30	98	79.954	Dipodomys_ordii
ENSG00000112996	MRPS30	100	80.182	ENSETEG00000006266	MRPS30	100	80.182	Echinops_telfairi
ENSG00000112996	MRPS30	98	47.166	ENSEBUG00000016559	mrps30	89	48.615	Eptatretus_burgeri
ENSG00000112996	MRPS30	100	82.916	ENSEASG00005013467	MRPS30	100	83.144	Equus_asinus_asinus
ENSG00000112996	MRPS30	100	82.688	ENSECAG00000009350	MRPS30	100	83.371	Equus_caballus
ENSG00000112996	MRPS30	84	80.000	ENSEEUG00000013893	MRPS30	99	79.447	Erinaceus_europaeus
ENSG00000112996	MRPS30	94	51.179	ENSELUG00000014642	mrps30	93	52.500	Esox_lucius
ENSG00000112996	MRPS30	100	83.827	ENSFCAG00000028632	MRPS30	100	83.599	Felis_catus
ENSG00000112996	MRPS30	100	82.005	ENSFDAG00000019454	MRPS30	100	82.005	Fukomys_damarensis
ENSG00000112996	MRPS30	91	50.617	ENSFHEG00000004052	mrps30	93	50.505	Fundulus_heteroclitus
ENSG00000112996	MRPS30	94	47.268	ENSGMOG00000012960	mrps30	99	47.268	Gadus_morhua
ENSG00000112996	MRPS30	93	63.729	ENSGALG00000014874	MRPS30	99	53.222	Gallus_gallus
ENSG00000112996	MRPS30	90	53.750	ENSGAFG00000016889	mrps30	93	53.000	Gambusia_affinis
ENSG00000112996	MRPS30	88	48.756	ENSGACG00000013789	mrps30	93	49.268	Gasterosteus_aculeatus
ENSG00000112996	MRPS30	98	62.645	ENSGAGG00000014136	MRPS30	99	63.109	Gopherus_agassizii
ENSG00000112996	MRPS30	100	99.317	ENSGGOG00000016095	MRPS30	100	99.317	Gorilla_gorilla
ENSG00000112996	MRPS30	97	51.163	ENSHBUG00000000852	mrps30	92	52.835	Haplochromis_burtoni
ENSG00000112996	MRPS30	100	81.321	ENSHGLG00000007915	MRPS30	100	81.321	Heterocephalus_glaber_female
ENSG00000112996	MRPS30	100	81.093	ENSHGLG00100015140	MRPS30	100	81.093	Heterocephalus_glaber_male
ENSG00000112996	MRPS30	89	48.775	ENSHCOG00000008085	mrps30	93	49.275	Hippocampus_comes
ENSG00000112996	MRPS30	88	55.440	ENSIPUG00000015530	mrps30	91	54.177	Ictalurus_punctatus
ENSG00000112996	MRPS30	100	80.866	ENSSTOG00000015844	MRPS30	100	80.410	Ictidomys_tridecemlineatus
ENSG00000112996	MRPS30	99	64.612	ENSJJAG00000007272	Mrps30	99	64.840	Jaculus_jaculus
ENSG00000112996	MRPS30	88	54.242	ENSKMAG00000007615	mrps30	94	53.283	Kryptolebias_marmoratus
ENSG00000112996	MRPS30	90	53.202	ENSLBEG00000026237	mrps30	94	52.709	Labrus_bergylta
ENSG00000112996	MRPS30	94	52.804	ENSLACG00000000083	MRPS30	93	52.195	Latimeria_chalumnae
ENSG00000112996	MRPS30	88	58.098	ENSLOCG00000011976	mrps30	91	57.990	Lepisosteus_oculatus
ENSG00000112996	MRPS30	99	80.499	ENSLAFG00000005809	MRPS30	100	80.045	Loxodonta_africana
ENSG00000112996	MRPS30	100	95.900	ENSMFAG00000037068	MRPS30	100	95.900	Macaca_fascicularis
ENSG00000112996	MRPS30	100	96.128	ENSMMUG00000016180	MRPS30	100	96.128	Macaca_mulatta
ENSG00000112996	MRPS30	100	95.672	ENSMNEG00000040760	MRPS30	100	95.672	Macaca_nemestrina
ENSG00000112996	MRPS30	100	96.355	ENSMLEG00000029243	MRPS30	100	96.355	Mandrillus_leucophaeus
ENSG00000112996	MRPS30	95	50.957	ENSMAMG00000006544	mrps30	94	52.417	Mastacembelus_armatus
ENSG00000112996	MRPS30	88	52.956	ENSMZEG00005013678	mrps30	92	52.320	Maylandia_zebra
ENSG00000112996	MRPS30	100	72.437	ENSMAUG00000013462	Mrps30	98	73.864	Mesocricetus_auratus
ENSG00000112996	MRPS30	100	82.460	ENSMICG00000008017	MRPS30	100	83.371	Microcebus_murinus
ENSG00000112996	MRPS30	99	75.917	ENSMOCG00000019175	Mrps30	97	76.606	Microtus_ochrogaster
ENSG00000112996	MRPS30	97	49.657	ENSMMOG00000017960	mrps30	92	51.263	Mola_mola
ENSG00000112996	MRPS30	97	70.353	ENSMODG00000020268	MRPS30	94	72.818	Monodelphis_domestica
ENSG00000112996	MRPS30	90	52.956	ENSMALG00000005101	mrps30	94	51.724	Monopterus_albus
ENSG00000112996	MRPS30	99	73.516	MGP_CAROLIEiJ_G0018921	Mrps30	98	73.121	Mus_caroli
ENSG00000112996	MRPS30	99	72.998	ENSMUSG00000021731	Mrps30	98	73.576	Mus_musculus
ENSG00000112996	MRPS30	99	72.998	MGP_PahariEiJ_G0015991	Mrps30	98	73.804	Mus_pahari
ENSG00000112996	MRPS30	99	72.769	MGP_SPRETEiJ_G0019800	Mrps30	98	73.684	Mus_spretus
ENSG00000112996	MRPS30	99	81.524	ENSMPUG00000014405	MRPS30	100	81.755	Mustela_putorius_furo
ENSG00000112996	MRPS30	99	77.803	ENSMLUG00000006240	MRPS30	100	77.629	Myotis_lucifugus
ENSG00000112996	MRPS30	99	78.311	ENSNGAG00000016518	Mrps30	98	78.767	Nannospalax_galili
ENSG00000112996	MRPS30	97	51.163	ENSNBRG00000022896	mrps30	92	52.835	Neolamprologus_brichardi
ENSG00000112996	MRPS30	100	95.485	ENSNLEG00000010605	MRPS30	100	95.485	Nomascus_leucogenys
ENSG00000112996	MRPS30	63	54.787	ENSMEUG00000016135	-	56	61.111	Notamacropus_eugenii
ENSG00000112996	MRPS30	100	67.198	ENSOPRG00000013365	-	100	67.198	Ochotona_princeps
ENSG00000112996	MRPS30	97	50.930	ENSONIG00000016926	mrps30	92	52.835	Oreochromis_niloticus
ENSG00000112996	MRPS30	55	76.667	ENSOANG00000001659	-	100	76.667	Ornithorhynchus_anatinus
ENSG00000112996	MRPS30	90	79.345	ENSOCUG00000004207	MRPS30	95	80.101	Oryctolagus_cuniculus
ENSG00000112996	MRPS30	97	49.886	ENSORLG00000001227	mrps30	94	51.244	Oryzias_latipes
ENSG00000112996	MRPS30	97	49.083	ENSORLG00020009592	mrps30	94	50.498	Oryzias_latipes_hni
ENSG00000112996	MRPS30	52	55.459	ENSORLG00015018978	mrps30	85	55.459	Oryzias_latipes_hsok
ENSG00000112996	MRPS30	52	55.895	ENSORLG00015018948	mrps30	53	55.895	Oryzias_latipes_hsok
ENSG00000112996	MRPS30	97	49.083	ENSORLG00015018671	mrps30	94	50.498	Oryzias_latipes_hsok
ENSG00000112996	MRPS30	90	51.493	ENSOMEG00000012836	mrps30	94	50.498	Oryzias_melastigma
ENSG00000112996	MRPS30	78	77.035	ENSOGAG00000001149	-	99	78.198	Otolemur_garnettii
ENSG00000112996	MRPS30	100	78.864	ENSOARG00000008516	MRPS30	100	78.864	Ovis_aries
ENSG00000112996	MRPS30	100	99.772	ENSPPAG00000030590	MRPS30	100	99.772	Pan_paniscus
ENSG00000112996	MRPS30	100	83.599	ENSPPRG00000001754	MRPS30	100	84.055	Panthera_pardus
ENSG00000112996	MRPS30	83	86.039	ENSPTIG00000016940	MRPS30	94	86.469	Panthera_tigris_altaica
ENSG00000112996	MRPS30	100	99.772	ENSPTRG00000016854	MRPS30	100	99.772	Pan_troglodytes
ENSG00000112996	MRPS30	100	96.355	ENSPANG00000004116	MRPS30	100	96.355	Papio_anubis
ENSG00000112996	MRPS30	88	51.777	ENSPKIG00000024011	mrps30	91	51.777	Paramormyrops_kingsleyae
ENSG00000112996	MRPS30	98	61.432	ENSPSIG00000004270	MRPS30	98	61.894	Pelodiscus_sinensis
ENSG00000112996	MRPS30	95	53.396	ENSPMGG00000006586	mrps30	94	55.112	Periophthalmus_magnuspinnatus
ENSG00000112996	MRPS30	54	84.322	ENSPEMG00000019509	Mrps30	96	84.322	Peromyscus_maniculatus_bairdii
ENSG00000112996	MRPS30	92	53.563	ENSPMAG00000001635	mrps30	98	53.634	Petromyzon_marinus
ENSG00000112996	MRPS30	90	72.335	ENSPCIG00000023080	-	93	72.180	Phascolarctos_cinereus
ENSG00000112996	MRPS30	88	53.807	ENSPFOG00000007213	mrps30	92	53.046	Poecilia_formosa
ENSG00000112996	MRPS30	88	53.807	ENSPLAG00000004649	mrps30	92	53.046	Poecilia_latipinna
ENSG00000112996	MRPS30	88	53.553	ENSPMEG00000017497	mrps30	92	52.792	Poecilia_mexicana
ENSG00000112996	MRPS30	90	52.750	ENSPREG00000008014	mrps30	93	52.500	Poecilia_reticulata
ENSG00000112996	MRPS30	100	90.455	ENSPPYG00000015445	MRPS30	100	90.455	Pongo_abelii
ENSG00000112996	MRPS30	100	80.317	ENSPCAG00000001587	MRPS30	100	80.090	Procavia_capensis
ENSG00000112996	MRPS30	100	83.599	ENSPCOG00000018431	MRPS30	100	84.282	Propithecus_coquereli
ENSG00000112996	MRPS30	100	82.916	ENSPVAG00000002302	MRPS30	100	83.371	Pteropus_vampyrus
ENSG00000112996	MRPS30	88	53.213	ENSPNYG00000016992	mrps30	92	52.577	Pundamilia_nyererei
ENSG00000112996	MRPS30	93	53.771	ENSPNAG00000029888	mrps30	83	53.117	Pygocentrus_nattereri
ENSG00000112996	MRPS30	100	72.437	ENSRNOG00000012136	Mrps30	98	73.349	Rattus_norvegicus
ENSG00000112996	MRPS30	57	93.574	ENSRBIG00000043339	MRPS30	100	93.574	Rhinopithecus_bieti
ENSG00000112996	MRPS30	100	94.305	ENSRROG00000033687	MRPS30	100	94.989	Rhinopithecus_roxellana
ENSG00000112996	MRPS30	100	88.838	ENSSBOG00000034220	MRPS30	100	88.610	Saimiri_boliviensis_boliviensis
ENSG00000112996	MRPS30	97	69.484	ENSSHAG00000005755	MRPS30	92	71.750	Sarcophilus_harrisii
ENSG00000112996	MRPS30	59	57.471	ENSSFOG00015001570	mrps30	95	57.471	Scleropages_formosus
ENSG00000112996	MRPS30	90	51.084	ENSSMAG00000008392	mrps30	94	50.120	Scophthalmus_maximus
ENSG00000112996	MRPS30	88	51.852	ENSSDUG00000022416	mrps30	91	50.990	Seriola_dumerili
ENSG00000112996	MRPS30	90	52.826	ENSSLDG00000004595	mrps30	94	51.463	Seriola_lalandi_dorsalis
ENSG00000112996	MRPS30	81	91.558	ENSSARG00000009420	MRPS30	80	91.558	Sorex_araneus
ENSG00000112996	MRPS30	98	59.629	ENSSPUG00000014071	MRPS30	99	59.397	Sphenodon_punctatus
ENSG00000112996	MRPS30	88	51.646	ENSSPAG00000013705	mrps30	86	51.139	Stegastes_partitus
ENSG00000112996	MRPS30	92	79.259	ENSSSCG00000032275	MRPS30	99	79.259	Sus_scrofa
ENSG00000112996	MRPS30	88	63.402	ENSTGUG00000002337	MRPS30	100	63.402	Taeniopygia_guttata
ENSG00000112996	MRPS30	97	51.152	ENSTRUG00000025594	mrps30	92	53.181	Takifugu_rubripes
ENSG00000112996	MRPS30	97	50.820	ENSTNIG00000015579	mrps30	94	52.405	Tetraodon_nigroviridis
ENSG00000112996	MRPS30	100	82.232	ENSTBEG00000005825	MRPS30	99	82.688	Tupaia_belangeri
ENSG00000112996	MRPS30	100	82.232	ENSTTRG00000008025	MRPS30	100	81.549	Tursiops_truncatus
ENSG00000112996	MRPS30	100	73.469	ENSUAMG00000007035	MRPS30	100	73.469	Ursus_americanus
ENSG00000112996	MRPS30	61	86.466	ENSUMAG00000005883	MRPS30	99	86.466	Ursus_maritimus
ENSG00000112996	MRPS30	100	81.321	ENSVPAG00000007070	MRPS30	100	81.321	Vicugna_pacos
ENSG00000112996	MRPS30	79	76.522	ENSVVUG00000025454	MRPS30	100	76.163	Vulpes_vulpes
ENSG00000112996	MRPS30	88	53.747	ENSXETG00000017716	mrps30	92	53.488	Xenopus_tropicalis
ENSG00000112996	MRPS30	90	53.500	ENSXCOG00000009616	mrps30	93	52.750	Xiphophorus_couchianus
ENSG00000112996	MRPS30	90	53.500	ENSXMAG00000003123	mrps30	93	52.750	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0003723	RNA binding	22658674.	HDA	Function
GO:0003735	structural constituent of ribosome	-	IEA	Function
GO:0005739	mitochondrion	21873635.	IBA	Component
GO:0005739	mitochondrion	28892042.	IDA	Component
GO:0005743	mitochondrial inner membrane	-	TAS	Component
GO:0005762	mitochondrial large ribosomal subunit	21873635.	IBA	Component
GO:0005762	mitochondrial large ribosomal subunit	28892042.	IDA	Component
GO:0006915	apoptotic process	10640817.	TAS	Process
GO:0070125	mitochondrial translational elongation	-	TAS	Process
GO:0070126	mitochondrial translational termination	-	TAS	Process

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
24388359	The 5p12 breast cancer susceptibility locus affects MRPS30 expression in estrogen-receptor positive tumors.	Mol Oncol	2014 Mar	Quigley DA	doi: 10.1016/j.molonc.2013.11.008
24528085	Breast cancer association studies in a Han Chinese population using 10 European-ancestry-associated breast cancer susceptibility SNPs.	Asian Pac J Cancer Prev	2014	Guan YP	-
27640304	Evidence that the 5p12 Variant rs10941679 Confers Susceptibility to Estrogen-Receptor-Positive Breast Cancer through FGF10 and MRPS30 Regulation.	Am J Hum Genet	2016 Oct 6	Ghoussaini M	doi: 10.1016/j.ajhg.2016.07.017

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
BLCA	chr5	44811072	Missense_Mutation	NA	R222Q	0.27	PDCD9
BLCA	chr5	44809090	Missense_Mutation	rs760640875	R43Q	0.33	PDCD9
BLCA	chr5	44809288	Missense_Mutation	NA	F109Y	0.42	PDCD9
BLCA	chr5	44815041	Missense_Mutation	novel	N387Y	0.25	PDCD9
BRCA	chr5	44813283	Splice_Site	NA	X344_splice	0.64
CESC	chr5	44809075	Missense_Mutation	novel	A38V	0.52	PDCD9
CESC	chr5	44813201	Missense_Mutation	NA	A317T	0.47	PDCD9
CESC	chr5	44808931	5'UTR	rs751700392		0.36
COAD	chr5	44809215	Missense_Mutation	NA	K85E	0.11	PDCD9
COAD	chr5	44814987	Frame_Shift_Del	NA	*F370Sfs5**	0.11	PDCD9
COAD	chr5	44815032	Missense_Mutation	NA	D384N	0.12	PDCD9
COAD	chr5	44813220	Frame_Shift_Del	rs764773638	*F324Lfs37**	0.37	PDCD9
COAD	chr5	44808931	5'UTR	rs751700392		0.56
COAD	chr5	44811096	Missense_Mutation	rs780785088	R230Q	0.34	PDCD9
COAD	chr5	44809232	Silent	novel	K90K	0.13
COAD	chr5	44809480	Missense_Mutation	NA	S173Y	0.08	PDCD9
COAD	chr5	44815064	Missense_Mutation	NA	W394C	0.19	PDCD9
ESCA	chr5	44811920	Silent	novel	V251V	0.61
GBM	chr5	44813209	Missense_Mutation	novel	Q319H	0.14	PDCD9
GBM	chr5	44809198	Missense_Mutation	novel	K79R	0.22	PDCD9
HNSC	chr5	44809359	Missense_Mutation	novel	P133S	0.12	PDCD9
HNSC	chr5	44814999	Nonsense_Mutation	rs549231581	Q373*	0.15	PDCD9
HNSC	chr5	44815294	3'UTR	novel		0.33
HNSC	chr5	44813109	Missense_Mutation	novel	S286L	0.13	PDCD9
HNSC	chr5	44811021	Missense_Mutation	novel	P205L	0.08	PDCD9
HNSC	chr5	44813190	Missense_Mutation	novel	R313K	0.08	PDCD9
HNSC	chr5	44809162	Missense_Mutation	novel	Q67L	0.22	PDCD9
KICH	chr5	44811993	Missense_Mutation	rs61753790	R276W	0.15	PDCD9
LGG	chr5	44808926	5'UTR	novel		0.42
LIHC	chr5	44809543	Missense_Mutation	novel	A194V	0.45	PDCD9
LUAD	chr5	44814944	Silent	novel	P354P	0.55
LUAD	chr5	44809562	Splice_Region	NA	L200L	0.15
LUAD	chr5	44809370	Silent	novel	A136A	0.17
LUAD	chr5	44815140	Nonsense_Mutation	NA	Q420*	0.13	PDCD9
LUAD	chr5	44809380	Missense_Mutation	NA	A140S	0.42	PDCD9
LUAD	chr5	44811149	Missense_Mutation	NA	A248S	0.13	PDCD9
LUSC	chr5	44811103	Silent	NA	Q232Q	0.13
LUSC	chr5	44815048	Missense_Mutation	rs753672352	R389H	0.2	PDCD9
LUSC	chr5	44809086	Missense_Mutation	novel	A42S	0.88	PDCD9
LUSC	chr5	44809266	Missense_Mutation	NA	A102P	0.4	PDCD9
LUSC	chr5	44809187	Silent	novel	S75S	0.07
LUSC	chr5	44811964	Missense_Mutation	novel	C266Y	0.42	PDCD9
LUSC	chr5	44815136	Silent	rs764476145	L418L	0.38
LUSC	chr5	44815082	Silent	NA	P400P	0.11
LUSC	chr5	44809196	Silent	NA	E78E	0.12
LUSC	chr5	44813153	Silent	NA	L301L	0.1
LUSC	chr5	44808926	5'UTR	novel		0.27
MESO	chr5	44809300	Missense_Mutation	novel	V113G	0.17	PDCD9
MESO	chr5	44809301	Silent	novel	V113V	0.17
OV	chr5	44815090	Missense_Mutation	novel	E403V	0.13	PDCD9
PAAD	chr5	44815144	Frame_Shift_Del	novel	*V422Yfs2**	0.14	PDCD9
PAAD	chr5	44811921	Missense_Mutation	novel	P252S	0.2	PDCD9
PAAD	chr5	44815213	3'UTR	novel		0.21
PRAD	chr5	44815096	Frame_Shift_Ins	novel	*E406Tfs9**	0.12	PDCD9
READ	chr5	44811945	Missense_Mutation	novel	E260K	0.47	PDCD9
READ	chr5	44814974	Silent	NA	G364G	0.33
SARC	chr5	44811081	Missense_Mutation	novel	R225Q	0.3	PDCD9
SKCM	chr5	44809347	Missense_Mutation	novel	P129S	0.5	PDCD9
SKCM	chr5	44809348	Missense_Mutation	novel	P129L	0.46	PDCD9
SKCM	chr5	44811081	Missense_Mutation	NA	R225L	0.06	PDCD9
STAD	chr5	44809091	Silent	novel	R43R	0.3
STAD	chr5	44809001	Silent	NA	G13G	0.18
STAD	chr5	44811148	Silent	NA	L247L	0.32
STAD	chr5	44809171	Missense_Mutation	NA	V70A	0.14	PDCD9
STAD	chr5	44809466	Silent	NA	E168E	0.23
STAD	chr5	44815206	3'UTR	novel		0.24
STAD	chr5	44813148	Missense_Mutation	NA	F299C	0.14	PDCD9
STAD	chr5	44811062	Missense_Mutation	rs754190115	R219C	0.21	PDCD9
THCA	chr5	44809022	Silent	rs774669607	T20T	0.43
UCEC	chr5	44811131	Nonsense_Mutation	rs201364888	R242*	0.2	PDCD9
UCEC	chr5	44809106	Silent	novel	V48V	0.16
UCEC	chr5	44811939	Missense_Mutation	novel	P258S	0.54	PDCD9
UCEC	chr5	44809480	Missense_Mutation	NA	S173Y	0.37	PDCD9
UCEC	chr5	44811071	Nonsense_Mutation	NA	R222*	0.2	PDCD9
UCEC	chr5	44815081	Missense_Mutation	novel	P400L	0.34	PDCD9
UCEC	chr5	44815226	3'UTR	novel		0.33
UCEC	chr5	44815267	3'UTR	novel		0.41
UCEC	chr5	44815106	Missense_Mutation	novel	N408K	0.17	PDCD9
UCEC	chr5	44811072	Missense_Mutation	NA	R222Q	0.48	PDCD9
UCEC	chr5	44815192	Missense_Mutation	NA	L437S	0.29
UCEC	chr5	44814913	Missense_Mutation	NA	G344V	0.4	PDCD9
UCEC	chr5	44815190	Missense_Mutation	novel		0.1
UCEC	chr5	44813228	Missense_Mutation	novel	A326T	0.41	PDCD9
UCEC	chr5	44815238	3'UTR	rs775890424		0.29
UCEC	chr5	44809089	Missense_Mutation	novel	R43W	0.17	PDCD9
UCEC	chr5	44814966	Missense_Mutation	NA	T362A	0.33	PDCD9
UCEC	chr5	44809234	Missense_Mutation	novel	Y91C	0.3	PDCD9
UCEC	chr5	44814940	Missense_Mutation	NA	R353Q	0.09	PDCD9
UCEC	chr5	44811131	Nonsense_Mutation	rs201364888	R242*	0.48	PDCD9
UCEC	chr5	44811127	Missense_Mutation	rs372442166	Q240H	0.38	PDCD9
UCEC	chr5	44811063	Missense_Mutation	rs368376102	R219H	0.09	PDCD9
UCEC	chr5	44811945	Nonsense_Mutation	NA	E260*	0.21	PDCD9
UCEC	chr5	44813156	Silent	rs764673573	L302L	0.21
UCEC	chr5	44815048	Missense_Mutation	rs753672352	R389H	0.26	PDCD9
UCEC	chr5	44811041	Missense_Mutation	rs534375825	R212C	0.18	PDCD9
UCEC	chr5	44815183	Nonsense_Mutation	novel	S434*	0.09
UCEC	chr5	44811102	Missense_Mutation	novel	Q232L	0.04	PDCD9
UCEC	chr5	44815370	3'UTR	novel		0.23
UCEC	chr5	44809256	Silent	novel	F98F	0.29

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
CHOL	DEL	0.0556	0.16947
COAD	AMP	0.1574	0.030224
HNSC	AMP	0.3448	0.018866
LUAD	AMP	0.5	6.849e-09
LUSC	AMP	0.6467	3.0539e-09
MESO	DEL	0.023	0.20184
THCA	DEL	0	0.23456

Survival Analysis

Cancer	P-value	Q-value
KIRC	0.0001	Kaplan-Meier Survival Analysis
SARC	0.023	Kaplan-Meier Survival Analysis
SKCM	0.0052	Kaplan-Meier Survival Analysis
PRAD	0.045	Kaplan-Meier Survival Analysis
BLCA	0.01	Kaplan-Meier Survival Analysis
KICH	0.0029	Kaplan-Meier Survival Analysis
GBM	0.011	Kaplan-Meier Survival Analysis
LIHC	0.00025	Kaplan-Meier Survival Analysis

Drugs

EuRBPDB

Description

RBDs

RBPome

Expression

Transcripts

Gene Model

Phenotypes

PPI

Orthologs

Gene Ontology

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742