EuRBPDB

Description

Ensembl ID: ENSG00000113282 (Gene tree)
Gene ID: 9685
Gene Symbol: CLINT1
Alias: ENTH|KIAA0171|EPNR|CLINT
Full Name: clathrin interactor 1
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Minus strand
Length: 73,433 bases
Position: chr5:157,785,743-157,859,175
Accession: 23186
RBP type: non-canonical RBP
Summary: This gene encodes a protein with similarity to the epsin family of endocytic adapter proteins. The encoded protein interacts with clathrin, the adapter protein AP-1 and phosphoinositides. This protein may be involved in the formation of clathrin coated vesicles and trafficking between the trans-Golgi network and endosomes. Mutations in this gene are associated with a susceptibility to schizophrenia and psychotic disorders. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2010]

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000523094	CLINT1-206	3987	-	ENSP00000429345	625 (aa)	-	Q14677
ENST00000522381	CLINT1-205	721	-	ENSP00000434334	66 (aa)	-	H0YDU9
ENST00000523908	CLINT1-207	2346	XM_011534701	ENSP00000429824	643 (aa)	XP_011533003	Q14677
ENST00000411809	CLINT1-201	3440	XM_017010087	ENSP00000388340	625 (aa)	XP_016865576	Q14677
ENST00000530742	CLINT1-210	3344	-	ENSP00000433419	625 (aa)	-	Q14677
ENST00000518855	CLINT1-202	3394	-	-	- (aa)	-	-
ENST00000530302	CLINT1-209	668	-	-	- (aa)	-	-
ENST00000521615	CLINT1-204	399	-	ENSP00000433013	133 (aa)	-	H0YD52
ENST00000521047	CLINT1-203	733	-	ENSP00000431858	55 (aa)	-	H0YCL3
ENST00000524306	CLINT1-208	2905	-	-	- (aa)	-	-

Gene Model

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000113282	Body Weight	6.41503010230249E-5	17903300
ENSG00000113282	Body Weight	2.18593421050794E-5	17903300
ENSG00000113282	Body Weight	3.19643899537869E-5	17903300
ENSG00000113282	Osteoporosis	4.193295492905E-6	17903296

Protein-Protein Interaction (PPI)

* RBP PPI network refers to all genes directly bind to RBP

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0005515	protein binding	12429846.14675752.18033301.20562859.26871637.	IPI	Function
GO:0005654	nucleoplasm	-	IDA	Component
GO:0005794	Golgi apparatus	10942595.	IDA	Component
GO:0005829	cytosol	-	TAS	Component
GO:0006897	endocytosis	-	IEA	Process
GO:0008289	lipid binding	-	IEA	Function
GO:0016020	membrane	19946888.	HDA	Component
GO:0030136	clathrin-coated vesicle	-	IEA	Component
GO:0030276	clathrin binding	12429846.	IPI	Function
GO:0043231	intracellular membrane-bounded organelle	-	IDA	Component
GO:0045296	cadherin binding	25468996.	HDA	Function
GO:0048268	clathrin coat assembly	-	IEA	Process
GO:0048471	perinuclear region of cytoplasm	-	IEA	Component