EuRBPDB

Description

RBDs

Literatures

Expression

Transcripts

Gene Model

Pathways

Phenotypes

GWAS

PPI

Paralogs

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000113300 (Gene tree)
Gene ID: 57472
Gene Symbol: CNOT6
Alias: CCR4|KIAA1194|Ccr4a
Full Name: CCR4-NOT transcription complex subunit 6
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Plus strand
Length: 84,033 bases
Position: chr5:180,494,373-180,578,405
Accession: 14099
RBP type: canonical RBP
Summary: This gene encodes the catalytic component of the CCR4-NOT core transcriptional regulation complex. The encoded protein has a 3'-5' RNase activity and prefers polyadenylated substrates. The CCR4-NOT complex plays a role in many cellular processes, including miRNA-mediated repression, mRNA degradation, and transcriptional regulation. [provided by RefSeq, Dec 2014]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000261951	Exo_endo_phos	PF03372.23	1.8e-21	1	1
ENSP00000377024	Exo_endo_phos	PF03372.23	1.8e-21	1	1
ENSP00000481893	Exo_endo_phos	PF03372.23	1.8e-21	1	1
ENSP00000422087	Exo_endo_phos	PF03372.23	3.4e-11	1	1

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
28954224	Alterations in mRNA 3' UTR Isoform Abundance Accompany Gene Expression Changes in Human Huntington's Disease Brains.	Cell Rep	2017 Sep 26	Romo L	doi: 10.1016/j.celrep.2017.09.009.
25100654	Deadenylase depletion protects inherited mRNAs in primordial germ cells.	Development	2014 Aug	Swartz SZ	doi: 10.1242/dev.110395.
21873511	RNA-binding protein Khd1 and Ccr4 deadenylase play overlapping roles in the cell wall integrity pathway in Saccharomyces cerevisiae.	Eukaryot Cell	2011 Oct	Ito W	doi: 10.1128/EC.05181-11
20953170	Maternal mRNA deadenylation and decay by the piRNA pathway in the early Drosophila embryo.	Nature	2010 Oct 28	Rouget C	doi: 10.1038/nature09465
23563484	Pbp1 is involved in Ccr4- and Khd1-mediated regulation of cell growth through association with ribosomal proteins Rpl12a and Rpl12b.	Eukaryot Cell	2013 Jun	Kimura Y	doi: 10.1128/EC.00370-12
25944446	The enzyme activities of Caf1 and Ccr4 are both required for deadenylation by the human Ccr4-Not nuclease module.	Biochem J	2015 Jul 1	Maryati M	doi: 10.1042/BJ20150304
29158339	Genome-Wide Mapping of Decay Factor-mRNA Interactions in Yeast Identifies Nutrient-Responsive Transcripts as Targets of the Deadenylase Ccr4.	G3 (Bethesda)	2018 Jan 4	Miller JE	doi: 10.1534/g3.117.300415.
30309886	The central region of CNOT1 and CNOT9 stimulates deadenylation by the Ccr4-Not nuclease module.	Biochem J	2018 Nov 9	Pavanello L	doi: 10.1042/BCJ20180456.
31093672	Identification of Arabidopsis CCR4-NOT complexes with Pumilio RNA binding proteins, APUM5 and APUM2.	Plant Cell Physiol	2019 May 15	Arae T	doi: 10.1093/pcp/pcz089
19716330	Mammalian miRNA RISC recruits CAF1 and PABP to affect PABP-dependent deadenylation.	Mol Cell	2009 Sep 24	Fabian MR	doi: 10.1016/j.molcel.2009.08.004
18180299	Components of the CCR4-NOT complex function as nuclear hormone receptor coactivators via association with the NRC-interacting Factor NIF-1.	J Biol Chem	2008 Mar 14	Garapaty S	doi: 10.1074/jbc.M706986200
24142921	Identification and characterization of FGF2-dependent mRNA: microRNA networks during lens fiber cell differentiation.	G3 (Bethesda)	2013 Dec 9	Wolf L	doi: 10.1534/g3.113.008698.

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000510148	CNOT6-206	456	-	-	- (aa)	-	-
ENST00000261951	CNOT6-201	6176	XM_005265953	ENSP00000261951	557 (aa)	XP_005266010	Q9ULM6
ENST00000507016	CNOT6-205	382	-	-	- (aa)	-	-
ENST00000393356	CNOT6-202	6303	-	ENSP00000377024	557 (aa)	-	Q9ULM6
ENST00000502447	CNOT6-203	552	-	-	- (aa)	-	-
ENST00000618123	CNOT6-207	6250	-	ENSP00000481893	557 (aa)	-	Q9ULM6
ENST00000504343	CNOT6-204	706	-	ENSP00000422087	234 (aa)	-	D6R9H6

Gene Model

Click here to download ENSG00000113300's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa03018	RNA degradation	KEGG

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000113300	Osteoporosis	4.42670305775827E-5	17903296
ENSG00000113300	Bone Density	2.57640866827558E-5	17903296

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000113300	rs78183295	5	180547479	C	Blood protein levels	30072576	[0.15-0.26] unit increase	0.204	EFO_0007937

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000113300's network

* RBP PPI network refers to all genes directly bind to RBP

Paralogs

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy
ENSG00000113300	CNOT6	100	89.474	ENSG00000138767	CNOT6L	100	87.975

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000113300	CNOT6	100	94.737	ENSAPOG00000009994	cnot6b	100	86.762	Acanthochromis_polyacanthus
ENSG00000113300	CNOT6	100	100.000	ENSAMEG00000000949	CNOT6	99	97.674	Ailuropoda_melanoleuca
ENSG00000113300	CNOT6	100	94.737	ENSACIG00000016566	cnot6b	100	85.689	Amphilophus_citrinellus
ENSG00000113300	CNOT6	100	94.737	ENSAOCG00000006893	cnot6b	100	86.762	Amphiprion_ocellaris
ENSG00000113300	CNOT6	100	94.737	ENSAPEG00000016949	cnot6b	100	86.762	Amphiprion_percula
ENSG00000113300	CNOT6	100	94.737	ENSATEG00000007862	cnot6b	100	84.615	Anabas_testudineus
ENSG00000113300	CNOT6	100	97.368	ENSAPLG00000012715	CNOT6	99	95.691	Anas_platyrhynchos
ENSG00000113300	CNOT6	100	97.368	ENSACAG00000016548	CNOT6	100	92.998	Anolis_carolinensis
ENSG00000113300	CNOT6	100	100.000	ENSANAG00000030436	CNOT6	96	98.923	Aotus_nancymaae
ENSG00000113300	CNOT6	100	94.737	ENSACLG00000008279	cnot6b	100	85.689	Astatotilapia_calliptera
ENSG00000113300	CNOT6	100	89.474	ENSAMXG00000034694	cnot6b	100	84.946	Astyanax_mexicanus
ENSG00000113300	CNOT6	100	92.105	ENSAMXG00000019140	cnot6a	100	86.380	Astyanax_mexicanus
ENSG00000113300	CNOT6	100	97.487	ENSBTAG00000017362	CNOT6	100	97.487	Bos_taurus
ENSG00000113300	CNOT6	100	98.743	ENSCJAG00000009795	CNOT6	100	98.743	Callithrix_jacchus
ENSG00000113300	CNOT6	100	98.025	ENSCAFG00000000464	CNOT6	100	98.025	Canis_familiaris
ENSG00000113300	CNOT6	100	98.025	ENSCAFG00020002441	CNOT6	100	98.025	Canis_lupus_dingo
ENSG00000113300	CNOT6	100	97.368	ENSCHIG00000019100	CNOT6	100	96.948	Capra_hircus
ENSG00000113300	CNOT6	100	96.230	ENSTSYG00000003982	CNOT6	100	96.230	Carlito_syrichta
ENSG00000113300	CNOT6	100	100.000	ENSCPOG00000035657	CNOT6	100	92.101	Cavia_porcellus
ENSG00000113300	CNOT6	100	94.255	ENSCCAG00000033670	CNOT6	100	94.255	Cebus_capucinus
ENSG00000113300	CNOT6	100	99.641	ENSCATG00000042014	CNOT6	100	99.641	Cercocebus_atys
ENSG00000113300	CNOT6	100	100.000	ENSCLAG00000010489	CNOT6	100	95.691	Chinchilla_lanigera
ENSG00000113300	CNOT6	100	99.641	ENSCSAG00000008165	CNOT6	100	99.641	Chlorocebus_sabaeus
ENSG00000113300	CNOT6	100	97.222	ENSCHOG00000009680	CNOT6	100	95.691	Choloepus_hoffmanni
ENSG00000113300	CNOT6	100	95.153	ENSCPBG00000008908	CNOT6	100	95.153	Chrysemys_picta_bellii
ENSG00000113300	CNOT6	100	99.461	ENSCANG00000026756	CNOT6	100	99.461	Colobus_angolensis_palliatus
ENSG00000113300	CNOT6	100	100.000	ENSCGRG00001011452	Cnot6	100	94.973	Cricetulus_griseus_chok1gshd
ENSG00000113300	CNOT6	100	100.000	ENSCGRG00000010407	Cnot6	100	93.357	Cricetulus_griseus_crigri
ENSG00000113300	CNOT6	100	94.737	ENSCSEG00000010939	cnot6b	100	85.868	Cynoglossus_semilaevis
ENSG00000113300	CNOT6	100	94.737	ENSCVAG00000010538	cnot6b	100	85.484	Cyprinodon_variegatus
ENSG00000113300	CNOT6	100	92.105	ENSDARG00000008255	cnot6a	100	85.842	Danio_rerio
ENSG00000113300	CNOT6	100	83.513	ENSDARG00000101072	cnot6b	100	83.513	Danio_rerio
ENSG00000113300	CNOT6	100	100.000	ENSDNOG00000041644	CNOT6	100	96.768	Dasypus_novemcinctus
ENSG00000113300	CNOT6	100	100.000	ENSDORG00000001708	Cnot6	100	86.535	Dipodomys_ordii
ENSG00000113300	CNOT6	100	100.000	ENSETEG00000006975	CNOT6	100	77.639	Echinops_telfairi
ENSG00000113300	CNOT6	100	100.000	ENSEASG00005012794	-	100	97.127	Equus_asinus_asinus
ENSG00000113300	CNOT6	90	91.400	ENSEASG00005012957	-	99	91.400	Equus_asinus_asinus
ENSG00000113300	CNOT6	100	100.000	ENSECAG00000019325	CNOT6	100	97.846	Equus_caballus
ENSG00000113300	CNOT6	100	92.105	ENSECAG00000012704	-	99	90.844	Equus_caballus
ENSG00000113300	CNOT6	98	100.000	ENSEEUG00000015382	CNOT6	100	96.589	Erinaceus_europaeus
ENSG00000113300	CNOT6	100	89.744	ENSELUG00000015981	cnot6b	99	83.245	Esox_lucius
ENSG00000113300	CNOT6	99	92.105	ENSELUG00000024580	cnot6a	100	81.900	Esox_lucius
ENSG00000113300	CNOT6	100	100.000	ENSFCAG00000001881	CNOT6	100	98.025	Felis_catus
ENSG00000113300	CNOT6	100	97.368	ENSFALG00000007699	CNOT6	100	95.691	Ficedula_albicollis
ENSG00000113300	CNOT6	100	100.000	ENSFDAG00000001999	CNOT6	100	95.512	Fukomys_damarensis
ENSG00000113300	CNOT6	65	88.095	ENSFHEG00000013756	cnot6b	96	88.095	Fundulus_heteroclitus
ENSG00000113300	CNOT6	100	89.474	ENSGMOG00000009767	cnot6b	99	84.877	Gadus_morhua
ENSG00000113300	CNOT6	100	97.368	ENSGALG00000034316	CNOT6	100	95.691	Gallus_gallus
ENSG00000113300	CNOT6	100	94.737	ENSGAFG00000008525	cnot6b	100	85.663	Gambusia_affinis
ENSG00000113300	CNOT6	100	80.841	ENSGACG00000018046	cnot6b	99	82.987	Gasterosteus_aculeatus
ENSG00000113300	CNOT6	100	94.737	ENSGAGG00000012176	CNOT6	100	79.174	Gopherus_agassizii
ENSG00000113300	CNOT6	100	100.000	ENSGGOG00000003675	CNOT6	100	100.000	Gorilla_gorilla
ENSG00000113300	CNOT6	100	94.737	ENSHBUG00000002819	cnot6b	100	85.868	Haplochromis_burtoni
ENSG00000113300	CNOT6	100	100.000	ENSHGLG00000017756	CNOT6	100	95.871	Heterocephalus_glaber_female
ENSG00000113300	CNOT6	100	100.000	ENSHGLG00100005747	CNOT6	100	95.871	Heterocephalus_glaber_male
ENSG00000113300	CNOT6	100	94.737	ENSHCOG00000016176	cnot6b	100	84.615	Hippocampus_comes
ENSG00000113300	CNOT6	100	94.737	ENSIPUG00000017482	cnot6b	100	84.409	Ictalurus_punctatus
ENSG00000113300	CNOT6	100	92.105	ENSIPUG00000019831	cnot6a	100	85.484	Ictalurus_punctatus
ENSG00000113300	CNOT6	100	97.127	ENSSTOG00000002803	CNOT6	100	97.127	Ictidomys_tridecemlineatus
ENSG00000113300	CNOT6	100	95.512	ENSJJAG00000012296	Cnot6	100	95.512	Jaculus_jaculus
ENSG00000113300	CNOT6	100	94.737	ENSKMAG00000004640	cnot6b	100	86.559	Kryptolebias_marmoratus
ENSG00000113300	CNOT6	100	92.105	ENSLBEG00000027917	cnot6b	100	84.794	Labrus_bergylta
ENSG00000113300	CNOT6	100	92.308	ENSLOCG00000010102	cnot6b	99	89.964	Lepisosteus_oculatus
ENSG00000113300	CNOT6	100	100.000	ENSLAFG00000016742	CNOT6	100	97.487	Loxodonta_africana
ENSG00000113300	CNOT6	100	99.641	ENSMFAG00000030867	CNOT6	100	99.641	Macaca_fascicularis
ENSG00000113300	CNOT6	100	99.641	ENSMMUG00000018690	CNOT6	100	99.641	Macaca_mulatta
ENSG00000113300	CNOT6	100	99.641	ENSMNEG00000038565	CNOT6	100	99.641	Macaca_nemestrina
ENSG00000113300	CNOT6	100	99.641	ENSMLEG00000010555	CNOT6	100	99.641	Mandrillus_leucophaeus
ENSG00000113300	CNOT6	100	94.737	ENSMAMG00000007515	cnot6b	100	86.941	Mastacembelus_armatus
ENSG00000113300	CNOT6	100	94.737	ENSMZEG00005012899	cnot6b	100	85.689	Maylandia_zebra
ENSG00000113300	CNOT6	100	100.000	ENSMAUG00000019798	Cnot6	100	96.050	Mesocricetus_auratus
ENSG00000113300	CNOT6	94	96.000	ENSMICG00000028378	-	99	87.500	Microcebus_murinus
ENSG00000113300	CNOT6	100	100.000	ENSMICG00000013018	-	100	96.050	Microcebus_murinus
ENSG00000113300	CNOT6	100	100.000	ENSMOCG00000021662	Cnot6	100	96.050	Microtus_ochrogaster
ENSG00000113300	CNOT6	100	92.105	ENSMMOG00000003227	cnot6b	100	84.050	Mola_mola
ENSG00000113300	CNOT6	100	97.368	ENSMODG00000003979	CNOT6	100	95.871	Monodelphis_domestica
ENSG00000113300	CNOT6	100	94.737	ENSMALG00000014251	cnot6b	100	86.583	Monopterus_albus
ENSG00000113300	CNOT6	100	100.000	MGP_CAROLIEiJ_G0016277	Cnot6	100	96.230	Mus_caroli
ENSG00000113300	CNOT6	100	100.000	ENSMUSG00000020362	Cnot6	100	96.230	Mus_musculus
ENSG00000113300	CNOT6	100	100.000	MGP_PahariEiJ_G0017413	Cnot6	100	96.230	Mus_pahari
ENSG00000113300	CNOT6	100	100.000	MGP_SPRETEiJ_G0017122	Cnot6	100	95.871	Mus_spretus
ENSG00000113300	CNOT6	100	100.000	ENSMPUG00000000587	CNOT6	96	97.846	Mustela_putorius_furo
ENSG00000113300	CNOT6	100	95.196	ENSMLUG00000010257	CNOT6	100	95.196	Myotis_lucifugus
ENSG00000113300	CNOT6	100	100.000	ENSNGAG00000008269	Cnot6	100	94.973	Nannospalax_galili
ENSG00000113300	CNOT6	100	94.737	ENSNBRG00000010798	cnot6b	100	85.868	Neolamprologus_brichardi
ENSG00000113300	CNOT6	100	100.000	ENSNLEG00000002322	CNOT6	100	98.564	Nomascus_leucogenys
ENSG00000113300	CNOT6	81	96.262	ENSMEUG00000000025	CNOT6	81	96.262	Notamacropus_eugenii
ENSG00000113300	CNOT6	100	91.589	ENSOPRG00000008244	-	88	95.943	Ochotona_princeps
ENSG00000113300	CNOT6	100	97.368	ENSODEG00000007041	CNOT6	100	94.794	Octodon_degus
ENSG00000113300	CNOT6	100	94.737	ENSONIG00000013027	cnot6b	99	85.343	Oreochromis_niloticus
ENSG00000113300	CNOT6	100	94.973	ENSOANG00000010226	CNOT6	100	94.973	Ornithorhynchus_anatinus
ENSG00000113300	CNOT6	100	100.000	ENSOCUG00000011083	CNOT6	100	96.243	Oryctolagus_cuniculus
ENSG00000113300	CNOT6	100	94.737	ENSORLG00000005059	cnot6b	100	85.152	Oryzias_latipes
ENSG00000113300	CNOT6	100	94.737	ENSORLG00020012784	cnot6b	100	85.152	Oryzias_latipes_hni
ENSG00000113300	CNOT6	100	94.737	ENSORLG00015022658	cnot6b	98	84.321	Oryzias_latipes_hsok
ENSG00000113300	CNOT6	100	94.737	ENSOMEG00000005295	cnot6b	100	85.331	Oryzias_melastigma
ENSG00000113300	CNOT6	94	97.328	ENSOGAG00000032470	CNOT6	100	97.328	Otolemur_garnettii
ENSG00000113300	CNOT6	97	96.679	ENSOARG00000001003	CNOT6	100	96.679	Ovis_aries
ENSG00000113300	CNOT6	100	100.000	ENSPPAG00000032253	CNOT6	100	100.000	Pan_paniscus
ENSG00000113300	CNOT6	100	100.000	ENSPPRG00000011912	CNOT6	100	97.846	Panthera_pardus
ENSG00000113300	CNOT6	100	100.000	ENSPTIG00000016794	CNOT6	100	97.846	Panthera_tigris_altaica
ENSG00000113300	CNOT6	100	100.000	ENSPTRG00000017636	CNOT6	100	100.000	Pan_troglodytes
ENSG00000113300	CNOT6	100	99.641	ENSPANG00000016191	CNOT6	100	99.641	Papio_anubis
ENSG00000113300	CNOT6	100	94.737	ENSPKIG00000021368	cnot6b	100	86.559	Paramormyrops_kingsleyae
ENSG00000113300	CNOT6	98	95.588	ENSPSIG00000017307	CNOT6	100	95.588	Pelodiscus_sinensis
ENSG00000113300	CNOT6	100	94.737	ENSPMGG00000011238	cnot6b	100	85.510	Periophthalmus_magnuspinnatus
ENSG00000113300	CNOT6	100	97.368	ENSPEMG00000000627	Cnot6	100	95.512	Peromyscus_maniculatus_bairdii
ENSG00000113300	CNOT6	100	97.368	ENSPCIG00000020319	CNOT6	99	95.691	Phascolarctos_cinereus
ENSG00000113300	CNOT6	100	94.737	ENSPFOG00000006291	cnot6b	100	85.484	Poecilia_formosa
ENSG00000113300	CNOT6	100	94.737	ENSPLAG00000008266	cnot6b	100	81.900	Poecilia_latipinna
ENSG00000113300	CNOT6	100	94.737	ENSPMEG00000009091	cnot6b	100	85.663	Poecilia_mexicana
ENSG00000113300	CNOT6	100	94.737	ENSPREG00000003713	cnot6b	100	84.409	Poecilia_reticulata
ENSG00000113300	CNOT6	100	100.000	ENSPPYG00000016137	CNOT6	100	100.000	Pongo_abelii
ENSG00000113300	CNOT6	71	96.617	ENSPCAG00000005599	-	71	96.617	Procavia_capensis
ENSG00000113300	CNOT6	100	92.101	ENSPCOG00000017359	CNOT6	100	92.819	Propithecus_coquereli
ENSG00000113300	CNOT6	100	92.101	ENSPVAG00000003069	CNOT6	100	92.101	Pteropus_vampyrus
ENSG00000113300	CNOT6	100	94.737	ENSPNYG00000000321	cnot6b	100	85.510	Pundamilia_nyererei
ENSG00000113300	CNOT6	100	92.105	ENSPNAG00000029586	cnot6a	100	86.559	Pygocentrus_nattereri
ENSG00000113300	CNOT6	100	86.842	ENSPNAG00000028816	cnot6b	100	85.305	Pygocentrus_nattereri
ENSG00000113300	CNOT6	100	100.000	ENSRNOG00000054891	Cnot6	100	95.332	Rattus_norvegicus
ENSG00000113300	CNOT6	100	99.461	ENSRBIG00000004309	CNOT6	100	99.461	Rhinopithecus_bieti
ENSG00000113300	CNOT6	100	99.461	ENSRROG00000035378	CNOT6	100	99.567	Rhinopithecus_roxellana
ENSG00000113300	CNOT6	100	100.000	ENSSBOG00000030494	CNOT6	100	98.743	Saimiri_boliviensis_boliviensis
ENSG00000113300	CNOT6	100	97.368	ENSSHAG00000017436	CNOT6	100	95.691	Sarcophilus_harrisii
ENSG00000113300	CNOT6	100	97.368	ENSSFOG00015015133	CNOT6	100	87.993	Scleropages_formosus
ENSG00000113300	CNOT6	100	94.737	ENSSFOG00015022383	cnot6a	96	85.663	Scleropages_formosus
ENSG00000113300	CNOT6	100	92.105	ENSSMAG00000003084	cnot6b	100	84.615	Scophthalmus_maximus
ENSG00000113300	CNOT6	100	94.737	ENSSDUG00000004151	cnot6b	100	86.404	Seriola_dumerili
ENSG00000113300	CNOT6	100	94.737	ENSSLDG00000004448	cnot6b	100	86.583	Seriola_lalandi_dorsalis
ENSG00000113300	CNOT6	67	88.199	ENSSARG00000012650	-	100	75.978	Sorex_araneus
ENSG00000113300	CNOT6	100	97.368	ENSSPUG00000007893	CNOT6	100	94.434	Sphenodon_punctatus
ENSG00000113300	CNOT6	100	94.737	ENSSPAG00000000149	cnot6b	100	86.583	Stegastes_partitus
ENSG00000113300	CNOT6	100	100.000	ENSSSCG00000014009	CNOT6	100	97.186	Sus_scrofa
ENSG00000113300	CNOT6	100	97.368	ENSTGUG00000001119	CNOT6	100	95.332	Taeniopygia_guttata
ENSG00000113300	CNOT6	100	94.737	ENSTRUG00000002818	cnot6b	100	84.022	Takifugu_rubripes
ENSG00000113300	CNOT6	100	94.737	ENSTNIG00000004443	cnot6b	99	84.381	Tetraodon_nigroviridis
ENSG00000113300	CNOT6	77	93.007	ENSTBEG00000017094	-	100	67.351	Tupaia_belangeri
ENSG00000113300	CNOT6	100	97.368	ENSTTRG00000009363	CNOT6	100	97.307	Tursiops_truncatus
ENSG00000113300	CNOT6	84	95.050	ENSUAMG00000004579	CNOT6	88	97.669	Ursus_americanus
ENSG00000113300	CNOT6	100	100.000	ENSUMAG00000024577	CNOT6	100	93.322	Ursus_maritimus
ENSG00000113300	CNOT6	99	94.595	ENSVPAG00000003593	CNOT6	83	96.028	Vicugna_pacos
ENSG00000113300	CNOT6	100	98.025	ENSVVUG00000026940	CNOT6	100	98.025	Vulpes_vulpes
ENSG00000113300	CNOT6	100	94.737	ENSXCOG00000003360	cnot6b	100	82.258	Xiphophorus_couchianus
ENSG00000113300	CNOT6	100	94.737	ENSXMAG00000008730	cnot6b	100	85.663	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening	20595389.	IMP	Process
GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening	-	TAS	Process
GO:0003723	RNA binding	-	IEA	Function
GO:0004532	exoribonuclease activity	11889047.	IDA	Function
GO:0004535	poly(A)-specific ribonuclease activity	11889047.18377426.	IDA	Function
GO:0004535	poly(A)-specific ribonuclease activity	-	TAS	Function
GO:0005515	protein binding	11747467.15687258.17452450.18180299.18326031.21981923.22977175.26496610.	IPI	Function
GO:0005634	nucleus	-	IEA	Component
GO:0005829	cytosol	-	TAS	Component
GO:0006417	regulation of translation	-	IEA	Process
GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	-	TAS	Process
GO:0008284	positive regulation of cell proliferation	21233283.	IMP	Process
GO:0010606	positive regulation of cytoplasmic mRNA processing body assembly	21233283.	IMP	Process
GO:0016020	membrane	19946888.	HDA	Component
GO:0030014	CCR4-NOT complex	19558367.	IDA	Component
GO:0035195	gene silencing by miRNA	20065043.	TAS	Process
GO:0043928	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay	20065043.	IDA	Process
GO:0046872	metal ion binding	-	IEA	Function
GO:0070966	nuclear-transcribed mRNA catabolic process, no-go decay	15314026.	IMP	Process
GO:0090503	RNA phosphodiester bond hydrolysis, exonucleolytic	-	IEA	Process
GO:2000327	positive regulation of nuclear receptor transcription coactivator activity	18180299.	IDA	Process