EuRBPDB

Description

RBDs

RBPome

Expression

Transcripts

Gene Model

Pathways

PPI

Paralogs

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000114784 (Gene tree)
Gene ID: 10289
Gene Symbol: EIF1B
Alias: GC20
Full Name: eukaryotic translation initiation factor 1B
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Plus strand
Length: 2,743 bases
Position: chr3:40,309,682-40,312,424
Accession: 30792
RBP type: canonical RBP
Summary: (Eukaryotic Translation Initiation Factor 1B) is a Protein Coding gene. Diseases associated with EIF1B include Acquired Thrombocytopenia. Among its related pathways are RNA transport. Gene Ontology (GO) annotations related to this gene include translation initiation factor activity. An important paralog of this gene is EIF1.

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000232905	SUI1	PF01253.22	1.4e-28	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
22681889	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts	4SURIC & HEK293	2012 May	Baltz AG	DOI: 10.1016/j.molcel.2012.05.021

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000232905	EIF1B-201	1010	-	ENSP00000232905	113 (aa)	-	O60739
ENST00000488260	EIF1B-204	637	-	-	- (aa)	-	-
ENST00000487151	EIF1B-203	632	-	-	- (aa)	-	-
ENST00000462088	EIF1B-202	873	-	-	- (aa)	-	-

Gene Model

Click here to download ENSG00000114784's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa03013	RNA transport	KEGG

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000114784's network

* RBP PPI network refers to all genes directly bind to RBP

Paralogs

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy
ENSG00000114784	EIF1B	100	92.035	ENSG00000173812	EIF1	100	92.035

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000114784	EIF1B	100	100.000	ENSAMEG00000001679	EIF1B	100	100.000	Ailuropoda_melanoleuca
ENSG00000114784	EIF1B	100	61.947	ENSACIG00000009618	zgc:56676	100	53.982	Amphilophus_citrinellus
ENSG00000114784	EIF1B	100	97.368	ENSAPLG00000001143	EIF1B	100	97.368	Anas_platyrhynchos
ENSG00000114784	EIF1B	91	100.000	ENSACAG00000017884	EIF1B	95	100.000	Anolis_carolinensis
ENSG00000114784	EIF1B	100	100.000	ENSANAG00000026979	EIF1B	100	100.000	Aotus_nancymaae
ENSG00000114784	EIF1B	100	95.575	ENSAMXG00000033877	zgc:56676	100	95.575	Astyanax_mexicanus
ENSG00000114784	EIF1B	100	100.000	ENSBTAG00000019106	EIF1B	100	100.000	Bos_taurus
ENSG00000114784	EIF1B	73	65.854	WBGene00020868	eif-1	75	65.854	Caenorhabditis_elegans
ENSG00000114784	EIF1B	100	100.000	ENSCJAG00000046513	EIF1B	100	100.000	Callithrix_jacchus
ENSG00000114784	EIF1B	60	91.176	ENSCAFG00000029183	EIF1B	80	100.000	Canis_familiaris
ENSG00000114784	EIF1B	100	100.000	ENSCAFG00020025518	EIF1B	100	100.000	Canis_lupus_dingo
ENSG00000114784	EIF1B	58	100.000	ENSCHIG00000022430	EIF1B	79	100.000	Capra_hircus
ENSG00000114784	EIF1B	100	100.000	ENSTSYG00000006338	EIF1B	100	100.000	Carlito_syrichta
ENSG00000114784	EIF1B	100	100.000	ENSCPOG00000035400	EIF1B	100	100.000	Cavia_porcellus
ENSG00000114784	EIF1B	100	100.000	ENSCCAG00000031083	EIF1B	100	100.000	Cebus_capucinus
ENSG00000114784	EIF1B	100	100.000	ENSCATG00000016704	EIF1B	100	100.000	Cercocebus_atys
ENSG00000114784	EIF1B	90	100.000	ENSCLAG00000016040	EIF1B	100	100.000	Chinchilla_lanigera
ENSG00000114784	EIF1B	100	100.000	ENSCSAG00000016916	EIF1B	100	100.000	Chlorocebus_sabaeus
ENSG00000114784	EIF1B	90	98.039	ENSCHOG00000009555	EIF1B	100	98.039	Choloepus_hoffmanni
ENSG00000114784	EIF1B	100	100.000	ENSCPBG00000000106	EIF1B	100	100.000	Chrysemys_picta_bellii
ENSG00000114784	EIF1B	100	100.000	ENSCANG00000043425	EIF1B	100	100.000	Colobus_angolensis_palliatus
ENSG00000114784	EIF1B	100	100.000	ENSCGRG00001004908	Eif1b	100	100.000	Cricetulus_griseus_chok1gshd
ENSG00000114784	EIF1B	90	100.000	ENSCGRG00000013833	Eif1b	100	100.000	Cricetulus_griseus_crigri
ENSG00000114784	EIF1B	100	96.460	ENSDARG00000029445	zgc:56676	100	96.460	Danio_rerio
ENSG00000114784	EIF1B	91	100.000	ENSDORG00000025252	Eif1b	100	100.000	Dipodomys_ordii
ENSG00000114784	EIF1B	100	100.000	ENSETEG00000017295	EIF1B	100	100.000	Echinops_telfairi
ENSG00000114784	EIF1B	100	100.000	ENSEASG00005007609	EIF1B	100	100.000	Equus_asinus_asinus
ENSG00000114784	EIF1B	100	100.000	ENSECAG00000005758	EIF1B	100	100.000	Equus_caballus
ENSG00000114784	EIF1B	100	92.920	ENSELUG00000002720	zgc:56676	100	93.137	Esox_lucius
ENSG00000114784	EIF1B	100	100.000	ENSFCAG00000003255	EIF1B	100	100.000	Felis_catus
ENSG00000114784	EIF1B	90	99.020	ENSFALG00000012290	EIF1B	91	99.020	Ficedula_albicollis
ENSG00000114784	EIF1B	100	100.000	ENSFDAG00000007219	EIF1B	100	100.000	Fukomys_damarensis
ENSG00000114784	EIF1B	100	89.381	ENSGMOG00000009623	-	100	89.381	Gadus_morhua
ENSG00000114784	EIF1B	100	98.230	ENSGALG00000038646	EIF1B	100	98.230	Gallus_gallus
ENSG00000114784	EIF1B	100	100.000	ENSGAGG00000011376	EIF1B	100	100.000	Gopherus_agassizii
ENSG00000114784	EIF1B	100	100.000	ENSGGOG00000008312	EIF1B	100	100.000	Gorilla_gorilla
ENSG00000114784	EIF1B	100	100.000	ENSHGLG00100006444	EIF1B	100	100.000	Heterocephalus_glaber_male
ENSG00000114784	EIF1B	98	72.973	ENSIPUG00000012511	-	98	72.973	Ictalurus_punctatus
ENSG00000114784	EIF1B	100	100.000	ENSSTOG00000012168	EIF1B	100	100.000	Ictidomys_tridecemlineatus
ENSG00000114784	EIF1B	90	98.039	ENSJJAG00000020423	Eif1b	100	98.039	Jaculus_jaculus
ENSG00000114784	EIF1B	100	96.460	ENSLACG00000004014	-	100	96.460	Latimeria_chalumnae
ENSG00000114784	EIF1B	94	85.849	ENSLACG00000022678	zgc:56676	97	85.849	Latimeria_chalumnae
ENSG00000114784	EIF1B	100	97.345	ENSLOCG00000012941	EIF1B	89	97.345	Lepisosteus_oculatus
ENSG00000114784	EIF1B	100	100.000	ENSLAFG00000001140	EIF1B	100	100.000	Loxodonta_africana
ENSG00000114784	EIF1B	100	100.000	ENSMFAG00000037264	EIF1B	100	100.000	Macaca_fascicularis
ENSG00000114784	EIF1B	100	100.000	ENSMMUG00000040036	EIF1B	100	100.000	Macaca_mulatta
ENSG00000114784	EIF1B	100	100.000	ENSMNEG00000032776	EIF1B	100	100.000	Macaca_nemestrina
ENSG00000114784	EIF1B	100	100.000	ENSMLEG00000033348	EIF1B	100	100.000	Mandrillus_leucophaeus
ENSG00000114784	EIF1B	100	98.230	ENSMGAG00000011733	EIF1B	100	98.230	Meleagris_gallopavo
ENSG00000114784	EIF1B	100	100.000	ENSMAUG00000016815	Eif1b	100	100.000	Mesocricetus_auratus
ENSG00000114784	EIF1B	100	100.000	ENSMICG00000049308	EIF1B	100	100.000	Microcebus_murinus
ENSG00000114784	EIF1B	100	100.000	ENSMOCG00000000649	-	100	100.000	Microtus_ochrogaster
ENSG00000114784	EIF1B	100	98.246	ENSMOCG00000017712	-	100	98.246	Microtus_ochrogaster
ENSG00000114784	EIF1B	100	59.292	ENSMMOG00000020133	zgc:56676	100	51.327	Mola_mola
ENSG00000114784	EIF1B	100	100.000	ENSMODG00000011056	EIF1B	100	100.000	Monodelphis_domestica
ENSG00000114784	EIF1B	100	71.681	ENSMODG00000002449	-	100	71.681	Monodelphis_domestica
ENSG00000114784	EIF1B	100	100.000	MGP_CAROLIEiJ_G0032817	Eif1b	100	100.000	Mus_caroli
ENSG00000114784	EIF1B	100	100.000	ENSMUSG00000006941	Eif1b	100	100.000	Mus_musculus
ENSG00000114784	EIF1B	100	100.000	MGP_PahariEiJ_G0015684	Eif1b	100	100.000	Mus_pahari
ENSG00000114784	EIF1B	100	100.000	MGP_SPRETEiJ_G0033965	Eif1b	100	100.000	Mus_spretus
ENSG00000114784	EIF1B	100	100.000	ENSMPUG00000017958	EIF1B	100	100.000	Mustela_putorius_furo
ENSG00000114784	EIF1B	100	100.000	ENSMLUG00000014425	EIF1B	100	100.000	Myotis_lucifugus
ENSG00000114784	EIF1B	100	100.000	ENSNGAG00000006534	Eif1b	100	100.000	Nannospalax_galili
ENSG00000114784	EIF1B	100	100.000	ENSNLEG00000005660	EIF1B	100	100.000	Nomascus_leucogenys
ENSG00000114784	EIF1B	57	96.875	ENSMEUG00000007908	-	100	96.875	Notamacropus_eugenii
ENSG00000114784	EIF1B	100	96.460	ENSMEUG00000005336	-	100	96.460	Notamacropus_eugenii
ENSG00000114784	EIF1B	100	85.965	ENSOPRG00000001569	EIF1B	100	85.965	Ochotona_princeps
ENSG00000114784	EIF1B	100	100.000	ENSODEG00000010883	EIF1B	100	100.000	Octodon_degus
ENSG00000114784	EIF1B	91	100.000	ENSOANG00000003583	EIF1B	90	100.000	Ornithorhynchus_anatinus
ENSG00000114784	EIF1B	100	100.000	ENSOGAG00000025224	EIF1B	100	100.000	Otolemur_garnettii
ENSG00000114784	EIF1B	100	100.000	ENSOARG00000002622	EIF1B	100	100.000	Ovis_aries
ENSG00000114784	EIF1B	100	100.000	ENSPPAG00000028080	EIF1B	100	100.000	Pan_paniscus
ENSG00000114784	EIF1B	100	99.115	ENSPPRG00000003963	EIF1B	100	99.115	Panthera_pardus
ENSG00000114784	EIF1B	90	100.000	ENSPTIG00000013646	EIF1B	90	100.000	Panthera_tigris_altaica
ENSG00000114784	EIF1B	100	100.000	ENSPTRG00000014776	EIF1B	100	100.000	Pan_troglodytes
ENSG00000114784	EIF1B	100	100.000	ENSPANG00000033825	EIF1B	100	100.000	Papio_anubis
ENSG00000114784	EIF1B	100	99.115	ENSPKIG00000004040	zgc:56676	100	99.115	Paramormyrops_kingsleyae
ENSG00000114784	EIF1B	91	99.029	ENSPSIG00000002437	EIF1B	99	99.029	Pelodiscus_sinensis
ENSG00000114784	EIF1B	100	78.761	ENSPMGG00000006863	zgc:56676	100	78.761	Periophthalmus_magnuspinnatus
ENSG00000114784	EIF1B	100	77.876	ENSPEMG00000016270	-	97	72.566	Peromyscus_maniculatus_bairdii
ENSG00000114784	EIF1B	100	100.000	ENSPCIG00000016375	EIF1B	100	100.000	Phascolarctos_cinereus
ENSG00000114784	EIF1B	100	99.115	ENSPPYG00000025897	EIF1B	100	99.115	Pongo_abelii
ENSG00000114784	EIF1B	92	99.038	ENSPCAG00000015629	EIF1B	100	99.038	Procavia_capensis
ENSG00000114784	EIF1B	100	100.000	ENSPCOG00000020355	EIF1B	100	100.000	Propithecus_coquereli
ENSG00000114784	EIF1B	100	100.000	ENSPVAG00000013911	EIF1B	100	100.000	Pteropus_vampyrus
ENSG00000114784	EIF1B	100	95.575	ENSPNAG00000023915	zgc:56676	100	95.575	Pygocentrus_nattereri
ENSG00000114784	EIF1B	100	100.000	ENSRNOG00000018848	Eif1b	100	100.000	Rattus_norvegicus
ENSG00000114784	EIF1B	100	100.000	ENSRBIG00000006994	EIF1B	100	100.000	Rhinopithecus_bieti
ENSG00000114784	EIF1B	100	100.000	ENSRROG00000040263	EIF1B	100	100.000	Rhinopithecus_roxellana
ENSG00000114784	EIF1B	91	100.000	ENSSBOG00000023951	EIF1B	77	100.000	Saimiri_boliviensis_boliviensis
ENSG00000114784	EIF1B	100	76.106	ENSSHAG00000012996	-	100	73.451	Sarcophilus_harrisii
ENSG00000114784	EIF1B	93	99.048	ENSSHAG00000013510	-	93	99.048	Sarcophilus_harrisii
ENSG00000114784	EIF1B	100	99.115	ENSSFOG00015007208	zgc:56676	100	99.115	Scleropages_formosus
ENSG00000114784	EIF1B	100	99.115	ENSSPUG00000002378	EIF1B	100	99.115	Sphenodon_punctatus
ENSG00000114784	EIF1B	100	100.000	ENSSSCG00000011270	EIF1B	100	100.000	Sus_scrofa
ENSG00000114784	EIF1B	100	97.345	ENSTGUG00000004677	EIF1B	97	97.345	Taeniopygia_guttata
ENSG00000114784	EIF1B	100	98.230	ENSTBEG00000013185	EIF1B	100	98.230	Tupaia_belangeri
ENSG00000114784	EIF1B	100	100.000	ENSTTRG00000000163	EIF1B	100	100.000	Tursiops_truncatus
ENSG00000114784	EIF1B	89	99.010	ENSUAMG00000022317	EIF1B	93	99.010	Ursus_americanus
ENSG00000114784	EIF1B	90	100.000	ENSUMAG00000004559	EIF1B	85	100.000	Ursus_maritimus
ENSG00000114784	EIF1B	100	100.000	ENSVPAG00000000967	EIF1B	100	100.000	Vicugna_pacos
ENSG00000114784	EIF1B	100	100.000	ENSVVUG00000005565	EIF1B	100	100.000	Vulpes_vulpes
ENSG00000114784	EIF1B	100	96.460	ENSXETG00000000359	eif1b	100	96.460	Xenopus_tropicalis

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0003723	RNA binding	22681889.	HDA	Function
GO:0003723	RNA binding	21873635.	IBA	Function
GO:0003743	translation initiation factor activity	21873635.	IBA	Function
GO:0005575	cellular_component	-	ND	Component
GO:0006413	translational initiation	-	IEA	Process
GO:0006446	regulation of translational initiation	7904817.	NAS	Process
GO:0016282	eukaryotic 43S preinitiation complex	21873635.	IBA	Component
GO:0043024	ribosomal small subunit binding	21873635.	IBA	Function