EuRBPDB

Description

Ensembl ID: ENSG00000114857 (Gene tree)
Gene ID: 4820
Gene Symbol: NKTR
Alias: p104
Full Name: natural killer cell triggering receptor
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Plus strand
Length: 48,128 bases
Position: chr3:42,600,614-42,648,741
Accession: 7833
RBP type: non-canonical RBP
Summary: This gene encodes a membrane-anchored protein with a hydrophobic amino terminal domain and a cyclophilin-like PPIase domain. It is present on the surface of natural killer cells and facilitates their binding to targets. Its expression is regulated by IL2 activation of the cells. [provided by RefSeq, Jul 2008]

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
7961969	Association of yeast viral 23 S RNA with its putative RNA-dependent RNA polymerase.	J Biol Chem	1994 Nov 25	Esteban LM	-
15308662	The bipartite 3'-cis-acting signal for replication is required for formation of a ribonucleoprotein complex in vivo between the viral genome and its RNA polymerase in yeast 23 S RNA virus.	J Biol Chem	2004 Oct 15	Fujimura T	-

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000429888	NKTR-202	7325	-	ENSP00000404802	105 (aa)	-	A8K7K2
ENST00000459950	NKTR-205	2134	-	-	- (aa)	-	-
ENST00000478488	NKTR-214	698	-	-	- (aa)	-	-
ENST00000466553	NKTR-210	716	-	-	- (aa)	-	-
ENST00000472258	NKTR-213	576	-	-	- (aa)	-	-
ENST00000445842	NKTR-204	560	-	ENSP00000408660	104 (aa)	-	C9JMM5
ENST00000460910	NKTR-207	282	-	-	- (aa)	-	-
ENST00000232978	NKTR-201	7343	XM_006713171	ENSP00000232978	1462 (aa)	XP_006713234	P30414
ENST00000472127	NKTR-212	796	-	-	- (aa)	-	-
ENST00000460807	NKTR-206	894	-	-	- (aa)	-	-
ENST00000508351	NKTR-218	876	-	-	- (aa)	-	-
ENST00000468735	NKTR-211	7964	-	-	- (aa)	-	-
ENST00000465584	NKTR-209	3839	-	-	- (aa)	-	-
ENST00000498730	NKTR-217	4912	-	-	- (aa)	-	-
ENST00000442970	NKTR-203	646	-	ENSP00000390259	105 (aa)	-	A8K7K2
ENST00000617821	NKTR-219	7319	XM_011533747	ENSP00000482143	1162 (aa)	XP_011532049	A0A087WYW3
ENST00000464315	NKTR-208	544	-	-	- (aa)	-	-
ENST00000490189	NKTR-216	581	-	-	- (aa)	-	-
ENST00000487466	NKTR-215	2335	-	-	- (aa)	-	-

Gene Model

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000114857	Personality	9.227e-005	-
ENSG00000114857	Personality	6.485e-005	-
ENSG00000114857	Personality	6.485e-005	-
ENSG00000114857	Platelet Function Tests	4.7600000E-006	-
ENSG00000114857	Platelet Function Tests	4.7600000E-006	-
ENSG00000114857	Platelet Function Tests	4.7600000E-006	-

Protein-Protein Interaction (PPI)

* RBP PPI network refers to all genes directly bind to RBP

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000413	protein peptidyl-prolyl isomerization	20676357.	IDA	Process
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	21873635.	IBA	Function
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	20676357.	IDA	Function
GO:0005654	nucleoplasm	-	IDA	Component
GO:0005739	mitochondrion	-	IDA	Component
GO:0005829	cytosol	-	IDA	Component
GO:0005886	plasma membrane	-	IDA	Component
GO:0016018	cyclosporin A binding	21873635.	IBA	Function
GO:0016018	cyclosporin A binding	20676357.	IDA	Function
GO:0042026	protein refolding	21873635.	IBA	Process
GO:0051082	unfolded protein binding	21873635.	IBA	Function