EuRBPDB

Basic Information
Cancer Related Information

Description

RBDs

RBPome

Literatures

Expression

Transcripts

Gene Model

Pathways

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000115268 (Gene tree)
Gene ID: 6209
Gene Symbol: RPS15
Alias: RIG|MGC111130|S15
Full Name: ribosomal protein S15
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Plus strand
Length: 2,137 bases
Position: chr19:1,438,358-1,440,494
Accession: 10388
RBP type: canonical RBP
Summary: Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S19P family of ribosomal proteins. It is located in the cytoplasm. This gene has been found to be activated in various tumors, such as insulinomas, esophageal cancers, and colon cancers. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000466366	Ribosomal_S19	PF00203.21	1.4e-39	1	1
ENSP00000467676	Ribosomal_S19	PF00203.21	1.4e-39	1	1
ENSP00000474543	Ribosomal_S19	PF00203.21	1.4e-39	1	1
ENSP00000473953	Ribosomal_S19	PF00203.21	1.7e-39	1	1
ENSP00000474433	Ribosomal_S19	PF00203.21	1.7e-39	1	1
ENSP00000474970	Ribosomal_S19	PF00203.21	2.4e-39	1	1
ENSP00000467466	Ribosomal_S19	PF00203.21	2.8e-39	1	1
ENSP00000466010	Ribosomal_S19	PF00203.21	3.1e-39	1	1
ENSP00000467855	Ribosomal_S19	PF00203.21	5.6e-33	1	1
ENSP00000465055	Ribosomal_S19	PF00203.21	3.7e-24	1	1
ENSP00000475096	Ribosomal_S19	PF00203.21	4.3e-20	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
22681889	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts	4SURIC & HEK293	2012 May	Baltz AG	DOI: 10.1016/j.molcel.2012.05.021
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
29431736	Capturing the interactome of newly transcribed RNA	RIC & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
22658674	Insights into RNA biology from an atlas of mammalian mRNA-binding proteins	RIC & Hela	2012 May 31	Castello A	DOI: 10.1016/j.cell.2012.04.031
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30352994	Discovery of RNA-binding proteins and characterization of their dynamic responses by enhanced RNA interactome capture	RIC & Jurkat	2018 Oct 23	Perez-Perri JI	DOI:10.1038/s41467-018-06557-8

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
8794875	Interaction of the Bacillus stearothermophilus ribosomal protein S15 with 16 S rRNA: I. Defining the minimal RNA site.	J Mol Biol	1996 Aug 30	Batey RT	-
1329024	Conformity of RNAs that interact with tetranucleotide loop binding proteins.	Nucleic Acids Res	1992 Sep 11	Zwieb C	-
9562554	Conformational variability of the N-terminal helix in the structure of ribosomal protein S15.	Structure	1998 Apr 15	Clemons WM Jr	-
9208917	Ribosomal protein S15 from Thermus thermophilus--cloning, sequencing, overexpression of the gene and RNA-binding properties of the protein.	Eur J Biochem	1997 Jun 1	Serganov A	-
26675164	Co-evolution of Bacterial Ribosomal Protein S15 with Diverse mRNA Regulatory Structures.	PLoS Genet	2015 Dec 16	Slinger BL	doi: 10.1371/journal.pgen.1005720
10430898	Ligand-induced conformational changes observed in single RNA molecules.	Proc Natl Acad Sci U S A	1999 Aug 3	Ha T	-
8955900	Pseudoknot and translational control in the expression of the S15 ribosomal protein.	Biochimie	1996	Benard L	-
16682557	30S ribosomal subunits can be assembled in vivo without primary binding ribosomal protein S15.	RNA	2006 Jul	Bubunenko M	-
17259282	The conformational landscape of the ribosomal protein S15 and its influence on the protein interaction with 16S RNA.	Biophys J	2007 Apr 15	Crety T	-
30504830	Real-time assembly of ribonucleoprotein complexes on nascent RNA transcripts.	Nat Commun	2018 Nov 30	Duss O	doi: 10.1038/s41467-018-07423-3.

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000592623	RPS15-210	873	-	ENSP00000474433	118 (aa)	-	A0A0B4J2B4
ENST00000591032	RPS15-207	550	-	ENSP00000474970	135 (aa)	-	S4R417
ENST00000589656	RPS15-206	473	-	ENSP00000467855	141 (aa)	-	K7EQJ5
ENST00000591804	RPS15-208	711	-	ENSP00000474543	112 (aa)	-	K7EM56
ENST00000592588	RPS15-209	510	-	ENSP00000467466	145 (aa)	-	P62841
ENST00000586686	RPS15-205	562	-	ENSP00000467676	112 (aa)	-	K7EM56
ENST00000586656	RPS15-204	436	-	ENSP00000475096	68 (aa)	-	S4R456
ENST00000233609	RPS15-201	534	-	ENSP00000473953	118 (aa)	-	A0A0B4J2B4
ENST00000585665	RPS15-202	467	-	ENSP00000466366	112 (aa)	-	K7EM56
ENST00000592700	RPS15-211	1602	-	-	- (aa)	-	-
ENST00000617694	RPS15-213	338	-	ENSP00000483399	7 (aa)	-	A0A1Y8EIB3
ENST00000586096	RPS15-203	570	-	ENSP00000465055	129 (aa)	-	K7EJ78
ENST00000593052	RPS15-212	629	-	ENSP00000466010	152 (aa)	-	K7ELC2

Gene Model

Click here to download ENSG00000115268's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa03010	Ribosome	KEGG

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000115268's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000115268	RPS15	100	96.610	ENSAPOG00000015085	rps15	100	95.172	Acanthochromis_polyacanthus
ENSG00000115268	RPS15	100	96.610	ENSACIG00000020520	rps15	97	94.406	Amphilophus_citrinellus
ENSG00000115268	RPS15	100	96.610	ENSAOCG00000001359	rps15	100	95.172	Amphiprion_ocellaris
ENSG00000115268	RPS15	100	96.610	ENSAPEG00000015950	rps15	100	95.172	Amphiprion_percula
ENSG00000115268	RPS15	100	95.588	ENSATEG00000018167	rps15	96	95.105	Anabas_testudineus
ENSG00000115268	RPS15	63	81.429	ENSACAG00000001992	-	100	81.429	Anolis_carolinensis
ENSG00000115268	RPS15	100	67.376	ENSANAG00000033171	-	100	67.376	Aotus_nancymaae
ENSG00000115268	RPS15	100	100.000	ENSANAG00000034317	RPS15	100	100.000	Aotus_nancymaae
ENSG00000115268	RPS15	100	95.588	ENSANAG00000019826	-	91	95.041	Aotus_nancymaae
ENSG00000115268	RPS15	100	91.071	ENSANAG00000019706	-	100	90.265	Aotus_nancymaae
ENSG00000115268	RPS15	100	82.609	ENSANAG00000021425	-	99	77.483	Aotus_nancymaae
ENSG00000115268	RPS15	100	96.610	ENSACLG00000008029	rps15	100	95.172	Astatotilapia_calliptera
ENSG00000115268	RPS15	100	97.321	ENSAMXG00000019062	rps15	99	96.528	Astyanax_mexicanus
ENSG00000115268	RPS15	100	99.310	ENSBTAG00000019718	RPS15	100	99.310	Bos_taurus
ENSG00000115268	RPS15	98	73.944	WBGene00004484	rps-15	96	73.469	Caenorhabditis_elegans
ENSG00000115268	RPS15	100	100.000	ENSCJAG00000005632	RPS15	100	100.000	Callithrix_jacchus
ENSG00000115268	RPS15	100	100.000	ENSCAFG00000023247	RPS15	100	100.000	Canis_familiaris
ENSG00000115268	RPS15	99	71.642	ENSCAFG00020009275	-	88	72.662	Canis_lupus_dingo
ENSG00000115268	RPS15	100	100.000	ENSCAFG00020017177	-	100	100.000	Canis_lupus_dingo
ENSG00000115268	RPS15	100	99.153	ENSCHIG00000023211	-	100	99.306	Capra_hircus
ENSG00000115268	RPS15	88	57.480	ENSCHIG00000027190	-	83	55.118	Capra_hircus
ENSG00000115268	RPS15	100	97.458	ENSCHIG00000003203	-	100	96.552	Capra_hircus
ENSG00000115268	RPS15	100	87.586	ENSCHIG00000008793	-	100	84.138	Capra_hircus
ENSG00000115268	RPS15	100	71.429	ENSTSYG00000036980	-	99	71.053	Carlito_syrichta
ENSG00000115268	RPS15	84	80.851	ENSTSYG00000035184	-	98	80.851	Carlito_syrichta
ENSG00000115268	RPS15	100	100.000	ENSCAPG00000014667	-	100	100.000	Cavia_aperea
ENSG00000115268	RPS15	91	60.150	ENSCAPG00000012901	-	95	60.150	Cavia_aperea
ENSG00000115268	RPS15	91	61.654	ENSCPOG00000019542	-	95	61.654	Cavia_porcellus
ENSG00000115268	RPS15	100	100.000	ENSCPOG00000003968	-	100	100.000	Cavia_porcellus
ENSG00000115268	RPS15	96	90.654	ENSCCAG00000030113	-	100	80.392	Cebus_capucinus
ENSG00000115268	RPS15	100	83.824	ENSCCAG00000028837	-	91	84.112	Cebus_capucinus
ENSG00000115268	RPS15	100	100.000	ENSCCAG00000037411	RPS15	100	99.310	Cebus_capucinus
ENSG00000115268	RPS15	100	94.068	ENSCCAG00000025695	-	99	91.216	Cebus_capucinus
ENSG00000115268	RPS15	97	72.727	ENSCCAG00000038094	-	94	73.874	Cebus_capucinus
ENSG00000115268	RPS15	100	91.176	ENSCCAG00000026305	-	100	80.000	Cebus_capucinus
ENSG00000115268	RPS15	90	86.885	ENSCATG00000041691	-	94	76.978	Cercocebus_atys
ENSG00000115268	RPS15	100	100.000	ENSCATG00000042597	RPS15	100	99.342	Cercocebus_atys
ENSG00000115268	RPS15	84	83.158	ENSCLAG00000006341	-	96	67.123	Chinchilla_lanigera
ENSG00000115268	RPS15	100	100.000	ENSCLAG00000007248	-	100	100.000	Chinchilla_lanigera
ENSG00000115268	RPS15	100	100.000	ENSCSAG00000012113	RPS15	100	98.684	Chlorocebus_sabaeus
ENSG00000115268	RPS15	100	100.000	ENSCPBG00000022955	-	99	92.623	Chrysemys_picta_bellii
ENSG00000115268	RPS15	100	98.305	ENSCPBG00000014732	RPS15	98	95.946	Chrysemys_picta_bellii
ENSG00000115268	RPS15	100	82.203	ENSCING00000005083	-	90	83.333	Ciona_intestinalis
ENSG00000115268	RPS15	100	81.250	ENSCSAVG00000008262	-	96	82.609	Ciona_savignyi
ENSG00000115268	RPS15	100	100.000	ENSCANG00000038192	RPS15	100	100.000	Colobus_angolensis_palliatus
ENSG00000115268	RPS15	100	98.529	ENSCANG00000035729	-	96	93.860	Colobus_angolensis_palliatus
ENSG00000115268	RPS15	100	79.464	ENSCANG00000029459	-	100	74.510	Colobus_angolensis_palliatus
ENSG00000115268	RPS15	100	86.607	ENSCANG00000021659	-	99	86.957	Colobus_angolensis_palliatus
ENSG00000115268	RPS15	100	94.326	ENSCANG00000029975	-	100	94.326	Colobus_angolensis_palliatus
ENSG00000115268	RPS15	100	61.702	ENSCGRG00001017911	-	100	60.993	Cricetulus_griseus_chok1gshd
ENSG00000115268	RPS15	97	79.825	ENSCGRG00001016563	-	100	75.758	Cricetulus_griseus_chok1gshd
ENSG00000115268	RPS15	74	92.000	ENSCGRG00001016655	-	68	91.935	Cricetulus_griseus_chok1gshd
ENSG00000115268	RPS15	100	87.586	ENSCGRG00001000783	-	100	87.586	Cricetulus_griseus_chok1gshd
ENSG00000115268	RPS15	100	100.000	ENSCGRG00001000902	-	100	100.000	Cricetulus_griseus_chok1gshd
ENSG00000115268	RPS15	100	73.529	ENSCGRG00001014736	-	75	77.679	Cricetulus_griseus_chok1gshd
ENSG00000115268	RPS15	100	73.529	ENSCGRG00001015764	-	90	67.568	Cricetulus_griseus_chok1gshd
ENSG00000115268	RPS15	100	81.379	ENSCGRG00001006125	-	100	81.379	Cricetulus_griseus_chok1gshd
ENSG00000115268	RPS15	100	100.000	ENSCGRG00000014157	-	100	100.000	Cricetulus_griseus_crigri
ENSG00000115268	RPS15	100	87.586	ENSCGRG00000020049	-	100	87.586	Cricetulus_griseus_crigri
ENSG00000115268	RPS15	97	79.825	ENSCGRG00000002735	-	100	75.758	Cricetulus_griseus_crigri
ENSG00000115268	RPS15	74	94.000	ENSCGRG00000020057	-	66	95.000	Cricetulus_griseus_crigri
ENSG00000115268	RPS15	100	73.529	ENSCGRG00000019904	-	90	67.568	Cricetulus_griseus_crigri
ENSG00000115268	RPS15	100	81.379	ENSCGRG00000020030	-	100	81.379	Cricetulus_griseus_crigri
ENSG00000115268	RPS15	93	80.952	ENSCGRG00000002323	-	100	69.504	Cricetulus_griseus_crigri
ENSG00000115268	RPS15	100	83.898	ENSCGRG00000002040	-	100	82.069	Cricetulus_griseus_crigri
ENSG00000115268	RPS15	100	73.529	ENSCGRG00000008584	-	75	77.679	Cricetulus_griseus_crigri
ENSG00000115268	RPS15	100	96.610	ENSCSEG00000011691	rps15	100	93.793	Cynoglossus_semilaevis
ENSG00000115268	RPS15	100	95.763	ENSCVAG00000018000	rps15	99	96.212	Cyprinodon_variegatus
ENSG00000115268	RPS15	100	98.305	ENSDARG00000070849	rps15	100	97.241	Danio_rerio
ENSG00000115268	RPS15	97	67.164	ENSDNOG00000033783	-	76	81.538	Dasypus_novemcinctus
ENSG00000115268	RPS15	100	100.000	ENSDNOG00000048447	-	100	100.000	Dasypus_novemcinctus
ENSG00000115268	RPS15	100	82.143	ENSDNOG00000043882	-	94	81.379	Dasypus_novemcinctus
ENSG00000115268	RPS15	100	100.000	ENSDORG00000029404	-	100	100.000	Dipodomys_ordii
ENSG00000115268	RPS15	100	68.142	ENSDORG00000028647	-	100	66.438	Dipodomys_ordii
ENSG00000115268	RPS15	100	76.786	FBgn0034138	RpS15	100	75.510	Drosophila_melanogaster
ENSG00000115268	RPS15	100	99.310	ENSETEG00000000837	-	100	99.310	Echinops_telfairi
ENSG00000115268	RPS15	100	100.000	ENSETEG00000008645	-	100	99.310	Echinops_telfairi
ENSG00000115268	RPS15	100	92.857	ENSEBUG00000012933	rps15	97	92.958	Eptatretus_burgeri
ENSG00000115268	RPS15	100	100.000	ENSEASG00005021721	-	100	100.000	Equus_asinus_asinus
ENSG00000115268	RPS15	85	77.586	ENSEASG00005012648	-	64	74.118	Equus_asinus_asinus
ENSG00000115268	RPS15	91	76.471	ENSECAG00000020876	-	78	74.468	Equus_caballus
ENSG00000115268	RPS15	97	55.752	ENSECAG00000039303	-	75	62.500	Equus_caballus
ENSG00000115268	RPS15	100	96.610	ENSELUG00000020275	rps15	100	95.862	Esox_lucius
ENSG00000115268	RPS15	100	69.643	ENSFCAG00000027526	-	96	69.565	Felis_catus
ENSG00000115268	RPS15	100	100.000	ENSFCAG00000038889	-	100	100.000	Felis_catus
ENSG00000115268	RPS15	100	100.000	ENSFALG00000014013	RPS15	100	100.000	Ficedula_albicollis
ENSG00000115268	RPS15	100	100.000	ENSFDAG00000018218	RPS15	100	100.000	Fukomys_damarensis
ENSG00000115268	RPS15	100	95.763	ENSFHEG00000005934	rps15	100	94.483	Fundulus_heteroclitus
ENSG00000115268	RPS15	100	95.588	ENSGMOG00000020370	-	100	95.283	Gadus_morhua
ENSG00000115268	RPS15	100	96.610	ENSGMOG00000010247	rps15	100	95.833	Gadus_morhua
ENSG00000115268	RPS15	100	100.000	ENSGALG00000015195	RPS15	100	100.000	Gallus_gallus
ENSG00000115268	RPS15	100	95.763	ENSGAFG00000012907	rps15	100	94.483	Gambusia_affinis
ENSG00000115268	RPS15	100	96.610	ENSGACG00000015549	rps15	100	96.610	Gasterosteus_aculeatus
ENSG00000115268	RPS15	100	100.000	ENSGAGG00000014288	-	91	96.078	Gopherus_agassizii
ENSG00000115268	RPS15	100	85.593	ENSGAGG00000006142	-	100	83.051	Gopherus_agassizii
ENSG00000115268	RPS15	100	92.857	ENSGAGG00000021543	-	97	92.308	Gopherus_agassizii
ENSG00000115268	RPS15	100	93.750	ENSGGOG00000024722	-	100	93.750	Gorilla_gorilla
ENSG00000115268	RPS15	100	89.706	ENSGGOG00000026153	-	97	87.387	Gorilla_gorilla
ENSG00000115268	RPS15	100	100.000	ENSGGOG00000002818	RPS15	100	100.000	Gorilla_gorilla
ENSG00000115268	RPS15	100	96.610	ENSHBUG00000011425	rps15	100	95.172	Haplochromis_burtoni
ENSG00000115268	RPS15	100	74.483	ENSHGLG00000005138	-	100	72.414	Heterocephalus_glaber_female
ENSG00000115268	RPS15	100	100.000	ENSHGLG00000017342	RPS15	100	100.000	Heterocephalus_glaber_female
ENSG00000115268	RPS15	100	100.000	ENSHGLG00100002001	RPS15	100	100.000	Heterocephalus_glaber_male
ENSG00000115268	RPS15	100	74.483	ENSHGLG00100002573	-	100	72.414	Heterocephalus_glaber_male
ENSG00000115268	RPS15	100	96.610	ENSHCOG00000005948	rps15	100	95.172	Hippocampus_comes
ENSG00000115268	RPS15	100	97.458	ENSIPUG00000006958	rps15	100	97.241	Ictalurus_punctatus
ENSG00000115268	RPS15	100	99.310	ENSSTOG00000006423	RPS15	100	99.310	Ictidomys_tridecemlineatus
ENSG00000115268	RPS15	100	100.000	ENSJJAG00000010009	-	100	100.000	Jaculus_jaculus
ENSG00000115268	RPS15	100	67.586	ENSJJAG00000023733	-	100	66.897	Jaculus_jaculus
ENSG00000115268	RPS15	100	95.763	ENSKMAG00000015898	rps15	100	94.483	Kryptolebias_marmoratus
ENSG00000115268	RPS15	100	96.610	ENSLBEG00000013668	rps15	100	95.172	Labrus_bergylta
ENSG00000115268	RPS15	100	97.931	ENSLACG00000009571	RPS15	100	97.931	Latimeria_chalumnae
ENSG00000115268	RPS15	100	97.321	ENSLOCG00000002230	rps15	99	88.889	Lepisosteus_oculatus
ENSG00000115268	RPS15	100	100.000	ENSLAFG00000008738	-	99	97.931	Loxodonta_africana
ENSG00000115268	RPS15	100	59.322	ENSLAFG00000026076	-	100	57.143	Loxodonta_africana
ENSG00000115268	RPS15	100	71.429	ENSMFAG00000035793	-	100	71.034	Macaca_fascicularis
ENSG00000115268	RPS15	100	82.143	ENSMFAG00000034057	-	99	79.333	Macaca_fascicularis
ENSG00000115268	RPS15	100	100.000	ENSMFAG00000031749	RPS15	100	99.342	Macaca_fascicularis
ENSG00000115268	RPS15	90	88.525	ENSMFAG00000033965	-	94	78.417	Macaca_fascicularis
ENSG00000115268	RPS15	100	100.000	ENSMMUG00000003050	RPS15	100	99.342	Macaca_mulatta
ENSG00000115268	RPS15	100	82.143	ENSMMUG00000046996	-	100	80.000	Macaca_mulatta
ENSG00000115268	RPS15	100	76.786	ENSMMUG00000037595	-	100	73.103	Macaca_mulatta
ENSG00000115268	RPS15	100	71.429	ENSMNEG00000030988	-	100	71.034	Macaca_nemestrina
ENSG00000115268	RPS15	100	100.000	ENSMNEG00000028419	RPS15	100	99.342	Macaca_nemestrina
ENSG00000115268	RPS15	90	88.525	ENSMNEG00000035375	-	94	78.417	Macaca_nemestrina
ENSG00000115268	RPS15	100	78.571	ENSMLEG00000031740	-	100	75.172	Mandrillus_leucophaeus
ENSG00000115268	RPS15	100	82.353	ENSMLEG00000041559	-	90	83.721	Mandrillus_leucophaeus
ENSG00000115268	RPS15	100	100.000	ENSMLEG00000016828	RPS15	100	100.000	Mandrillus_leucophaeus
ENSG00000115268	RPS15	90	86.885	ENSMLEG00000037440	-	94	77.698	Mandrillus_leucophaeus
ENSG00000115268	RPS15	100	97.458	ENSMAMG00000005870	rps15	100	95.862	Mastacembelus_armatus
ENSG00000115268	RPS15	100	96.610	ENSMZEG00005003902	rps15	100	95.172	Maylandia_zebra
ENSG00000115268	RPS15	100	100.000	ENSMGAG00000004229	RPS15	99	100.000	Meleagris_gallopavo
ENSG00000115268	RPS15	94	72.464	ENSMAUG00000017616	-	74	69.504	Mesocricetus_auratus
ENSG00000115268	RPS15	100	100.000	ENSMAUG00000004679	Rps15	100	100.000	Mesocricetus_auratus
ENSG00000115268	RPS15	100	84.058	ENSMICG00000032959	-	96	83.582	Microcebus_murinus
ENSG00000115268	RPS15	100	97.241	ENSMICG00000027162	-	97	97.241	Microcebus_murinus
ENSG00000115268	RPS15	100	100.000	ENSMICG00000003586	RPS15	100	100.000	Microcebus_murinus
ENSG00000115268	RPS15	100	95.588	ENSMICG00000046256	-	98	87.736	Microcebus_murinus
ENSG00000115268	RPS15	100	93.103	ENSMOCG00000017900	-	97	91.216	Microtus_ochrogaster
ENSG00000115268	RPS15	100	94.915	ENSMOCG00000008827	-	100	93.793	Microtus_ochrogaster
ENSG00000115268	RPS15	100	86.441	ENSMOCG00000019947	-	100	84.138	Microtus_ochrogaster
ENSG00000115268	RPS15	100	98.529	ENSMOCG00000012010	-	100	85.106	Microtus_ochrogaster
ENSG00000115268	RPS15	100	100.000	ENSMOCG00000019754	-	100	100.000	Microtus_ochrogaster
ENSG00000115268	RPS15	100	98.305	ENSMOCG00000002622	-	99	98.611	Microtus_ochrogaster
ENSG00000115268	RPS15	82	96.739	ENSMMOG00000006249	rps15	100	71.250	Mola_mola
ENSG00000115268	RPS15	100	100.000	ENSMODG00000005119	-	73	100.000	Monodelphis_domestica
ENSG00000115268	RPS15	100	96.610	ENSMALG00000000645	rps15	99	87.218	Monopterus_albus
ENSG00000115268	RPS15	100	100.000	MGP_CAROLIEiJ_G0015575	-	100	100.000	Mus_caroli
ENSG00000115268	RPS15	100	100.000	ENSMUSG00000063457	Rps15	100	100.000	Mus_musculus
ENSG00000115268	RPS15	100	100.000	MGP_PahariEiJ_G0030988	-	100	100.000	Mus_pahari
ENSG00000115268	RPS15	100	100.000	MGP_SPRETEiJ_G0016393	-	100	100.000	Mus_spretus
ENSG00000115268	RPS15	100	80.882	MGP_SPRETEiJ_G0020479	-	100	82.734	Mus_spretus
ENSG00000115268	RPS15	100	70.588	ENSMPUG00000004876	-	100	70.345	Mustela_putorius_furo
ENSG00000115268	RPS15	100	79.487	ENSMLUG00000016413	-	100	75.817	Myotis_lucifugus
ENSG00000115268	RPS15	100	100.000	ENSNGAG00000023415	Rps15	100	100.000	Nannospalax_galili
ENSG00000115268	RPS15	100	96.610	ENSNBRG00000001176	rps15	97	95.139	Neolamprologus_brichardi
ENSG00000115268	RPS15	99	93.694	ENSNLEG00000018931	-	99	93.636	Nomascus_leucogenys
ENSG00000115268	RPS15	100	91.071	ENSNLEG00000030108	-	94	84.733	Nomascus_leucogenys
ENSG00000115268	RPS15	100	100.000	ENSNLEG00000034934	RPS15	100	100.000	Nomascus_leucogenys
ENSG00000115268	RPS15	96	97.196	ENSNLEG00000031244	-	98	97.196	Nomascus_leucogenys
ENSG00000115268	RPS15	100	91.525	ENSNLEG00000030813	-	97	90.909	Nomascus_leucogenys
ENSG00000115268	RPS15	97	100.000	ENSMEUG00000014053	RPS15	100	93.793	Notamacropus_eugenii
ENSG00000115268	RPS15	99	84.615	ENSODEG00000006504	-	86	84.615	Octodon_degus
ENSG00000115268	RPS15	100	79.661	ENSODEG00000013320	-	99	79.070	Octodon_degus
ENSG00000115268	RPS15	99	86.806	ENSODEG00000013410	-	99	86.806	Octodon_degus
ENSG00000115268	RPS15	100	82.759	ENSODEG00000003845	-	89	82.759	Octodon_degus
ENSG00000115268	RPS15	100	100.000	ENSODEG00000013650	-	100	100.000	Octodon_degus
ENSG00000115268	RPS15	100	89.706	ENSODEG00000019613	-	99	86.111	Octodon_degus
ENSG00000115268	RPS15	100	83.929	ENSODEG00000019071	-	100	83.448	Octodon_degus
ENSG00000115268	RPS15	100	96.610	ENSONIG00000010495	rps15	99	95.139	Oreochromis_niloticus
ENSG00000115268	RPS15	100	100.000	ENSOANG00000014514	RPS15	89	100.000	Ornithorhynchus_anatinus
ENSG00000115268	RPS15	100	99.310	ENSOCUG00000002862	-	100	99.310	Oryctolagus_cuniculus
ENSG00000115268	RPS15	100	95.763	ENSORLG00000005592	rps15	100	95.172	Oryzias_latipes
ENSG00000115268	RPS15	100	95.763	ENSORLG00020021865	rps15	100	95.172	Oryzias_latipes_hni
ENSG00000115268	RPS15	100	95.763	ENSORLG00015021938	rps15	100	95.172	Oryzias_latipes_hsok
ENSG00000115268	RPS15	100	95.588	ENSOMEG00000018049	rps15	100	94.815	Oryzias_melastigma
ENSG00000115268	RPS15	100	94.915	ENSOGAG00000024744	-	100	94.483	Otolemur_garnettii
ENSG00000115268	RPS15	100	79.333	ENSOGAG00000029353	-	100	76.667	Otolemur_garnettii
ENSG00000115268	RPS15	100	77.703	ENSOGAG00000024805	-	100	77.703	Otolemur_garnettii
ENSG00000115268	RPS15	100	82.353	ENSOGAG00000034923	-	100	75.177	Otolemur_garnettii
ENSG00000115268	RPS15	100	100.000	ENSOGAG00000015776	-	99	100.000	Otolemur_garnettii
ENSG00000115268	RPS15	100	92.373	ENSOGAG00000026108	-	100	88.112	Otolemur_garnettii
ENSG00000115268	RPS15	100	92.414	ENSOARG00000011763	-	100	92.414	Ovis_aries
ENSG00000115268	RPS15	100	91.964	ENSPPAG00000001220	-	100	91.964	Pan_paniscus
ENSG00000115268	RPS15	100	91.964	ENSPPAG00000040314	-	98	91.034	Pan_paniscus
ENSG00000115268	RPS15	100	94.118	ENSPPAG00000038459	-	98	82.707	Pan_paniscus
ENSG00000115268	RPS15	100	100.000	ENSPPAG00000015902	-	100	100.000	Pan_paniscus
ENSG00000115268	RPS15	100	70.536	ENSPPRG00000009097	-	93	69.231	Panthera_pardus
ENSG00000115268	RPS15	100	100.000	ENSPPRG00000013868	-	100	100.000	Panthera_pardus
ENSG00000115268	RPS15	100	65.217	ENSPTIG00000014749	-	100	56.494	Panthera_tigris_altaica
ENSG00000115268	RPS15	100	89.706	ENSPTRG00000042958	-	99	81.343	Pan_troglodytes
ENSG00000115268	RPS15	100	78.621	ENSPTRG00000044787	-	100	78.621	Pan_troglodytes
ENSG00000115268	RPS15	100	100.000	ENSPTRG00000010200	RPS15	100	100.000	Pan_troglodytes
ENSG00000115268	RPS15	100	91.071	ENSPTRG00000040744	-	98	90.345	Pan_troglodytes
ENSG00000115268	RPS15	99	92.793	ENSPTRG00000048422	-	100	88.276	Pan_troglodytes
ENSG00000115268	RPS15	96	90.769	ENSPTRG00000049946	-	78	84.314	Pan_troglodytes
ENSG00000115268	RPS15	91	88.710	ENSPANG00000018874	-	94	77.698	Papio_anubis
ENSG00000115268	RPS15	100	100.000	ENSPANG00000035087	RPS15	100	100.000	Papio_anubis
ENSG00000115268	RPS15	100	82.143	ENSPANG00000036128	-	99	78.808	Papio_anubis
ENSG00000115268	RPS15	100	96.610	ENSPKIG00000007094	-	99	97.015	Paramormyrops_kingsleyae
ENSG00000115268	RPS15	100	97.458	ENSPKIG00000007804	RPS15	100	97.241	Paramormyrops_kingsleyae
ENSG00000115268	RPS15	100	100.000	ENSPSIG00000002750	RPS15	86	100.000	Pelodiscus_sinensis
ENSG00000115268	RPS15	100	96.610	ENSPMGG00000017425	rps15	97	96.454	Periophthalmus_magnuspinnatus
ENSG00000115268	RPS15	100	96.610	ENSPEMG00000015006	-	100	95.172	Peromyscus_maniculatus_bairdii
ENSG00000115268	RPS15	100	100.000	ENSPEMG00000021829	Rps15	100	100.000	Peromyscus_maniculatus_bairdii
ENSG00000115268	RPS15	100	91.964	ENSPMAG00000004838	rps15	97	91.489	Petromyzon_marinus
ENSG00000115268	RPS15	100	100.000	ENSPCIG00000011152	-	100	100.000	Phascolarctos_cinereus
ENSG00000115268	RPS15	100	91.724	ENSPCIG00000025633	-	100	91.724	Phascolarctos_cinereus
ENSG00000115268	RPS15	100	88.983	ENSPCIG00000023901	-	99	84.768	Phascolarctos_cinereus
ENSG00000115268	RPS15	100	95.763	ENSPFOG00000003106	rps15	100	94.483	Poecilia_formosa
ENSG00000115268	RPS15	100	95.763	ENSPLAG00000008992	rps15	100	94.483	Poecilia_latipinna
ENSG00000115268	RPS15	100	95.763	ENSPMEG00000003085	rps15	100	94.483	Poecilia_mexicana
ENSG00000115268	RPS15	100	95.763	ENSPREG00000008866	rps15	100	94.483	Poecilia_reticulata
ENSG00000115268	RPS15	100	100.000	ENSPPYG00000009317	RPS15	100	100.000	Pongo_abelii
ENSG00000115268	RPS15	100	94.118	ENSPPYG00000010678	-	100	92.414	Pongo_abelii
ENSG00000115268	RPS15	100	100.000	ENSPCAG00000013681	RPS15	100	100.000	Procavia_capensis
ENSG00000115268	RPS15	100	100.000	ENSPCOG00000026500	RPS15	100	100.000	Propithecus_coquereli
ENSG00000115268	RPS15	100	100.000	ENSPCOG00000023173	-	99	96.053	Propithecus_coquereli
ENSG00000115268	RPS15	100	100.000	ENSPVAG00000003168	RPS15	100	100.000	Pteropus_vampyrus
ENSG00000115268	RPS15	100	95.588	ENSPNYG00000003242	rps15	85	86.992	Pundamilia_nyererei
ENSG00000115268	RPS15	100	97.458	ENSPNAG00000011565	rps15	100	94.958	Pygocentrus_nattereri
ENSG00000115268	RPS15	100	100.000	ENSRNOG00000024603	Rps15	100	100.000	Rattus_norvegicus
ENSG00000115268	RPS15	100	94.118	ENSRNOG00000043026	AC128207.2	87	95.370	Rattus_norvegicus
ENSG00000115268	RPS15	99	85.075	ENSRBIG00000032312	-	100	76.596	Rhinopithecus_bieti
ENSG00000115268	RPS15	100	100.000	ENSRBIG00000041908	RPS15	100	100.000	Rhinopithecus_bieti
ENSG00000115268	RPS15	100	85.714	ENSRBIG00000036227	-	99	86.087	Rhinopithecus_bieti
ENSG00000115268	RPS15	100	100.000	ENSRROG00000038546	RPS15	100	100.000	Rhinopithecus_roxellana
ENSG00000115268	RPS15	99	85.075	ENSRROG00000026617	-	99	72.549	Rhinopithecus_roxellana
ENSG00000115268	RPS15	100	75.000	ENSRROG00000030040	-	98	63.433	Rhinopithecus_roxellana
ENSG00000115268	RPS15	100	80.357	ENSRROG00000028353	-	99	80.870	Rhinopithecus_roxellana
ENSG00000115268	RPS15	100	62.500	YOL040C	RPS15	100	59.310	Saccharomyces_cerevisiae
ENSG00000115268	RPS15	100	100.000	ENSSBOG00000024826	-	100	100.000	Saimiri_boliviensis_boliviensis
ENSG00000115268	RPS15	100	77.419	ENSSBOG00000024371	-	100	72.956	Saimiri_boliviensis_boliviensis
ENSG00000115268	RPS15	100	77.679	ENSSBOG00000035797	-	82	77.119	Saimiri_boliviensis_boliviensis
ENSG00000115268	RPS15	100	99.310	ENSSHAG00000013424	RPS15	100	99.310	Sarcophilus_harrisii
ENSG00000115268	RPS15	100	92.647	ENSSFOG00015017203	-	100	91.071	Scleropages_formosus
ENSG00000115268	RPS15	100	99.153	ENSSFOG00015020320	rps15	100	97.931	Scleropages_formosus
ENSG00000115268	RPS15	100	96.610	ENSSMAG00000005382	rps15	100	94.483	Scophthalmus_maximus
ENSG00000115268	RPS15	100	96.610	ENSSDUG00000012842	rps15	100	95.172	Seriola_dumerili
ENSG00000115268	RPS15	100	65.000	ENSSLDG00000001173	-	95	65.972	Seriola_lalandi_dorsalis
ENSG00000115268	RPS15	100	96.610	ENSSLDG00000021227	rps15	100	95.172	Seriola_lalandi_dorsalis
ENSG00000115268	RPS15	100	94.118	ENSSARG00000005198	RPS15	100	87.500	Sorex_araneus
ENSG00000115268	RPS15	100	100.000	ENSSPUG00000006712	RPS15	100	99.310	Sphenodon_punctatus
ENSG00000115268	RPS15	100	96.610	ENSSPAG00000000016	rps15	100	95.172	Stegastes_partitus
ENSG00000115268	RPS15	99	65.672	ENSSSCG00000033091	-	100	66.964	Sus_scrofa
ENSG00000115268	RPS15	94	61.468	ENSSSCG00000015429	-	96	52.055	Sus_scrofa
ENSG00000115268	RPS15	93	59.259	ENSSSCG00000038060	-	95	62.602	Sus_scrofa
ENSG00000115268	RPS15	100	100.000	ENSSSCG00000033169	RPS15	100	100.000	Sus_scrofa
ENSG00000115268	RPS15	100	100.000	ENSTGUG00000000865	RPS15	99	100.000	Taeniopygia_guttata
ENSG00000115268	RPS15	100	96.610	ENSTRUG00000009730	rps15	99	96.970	Takifugu_rubripes
ENSG00000115268	RPS15	100	96.610	ENSTNIG00000011064	rps15	100	95.172	Tetraodon_nigroviridis
ENSG00000115268	RPS15	100	100.000	ENSUAMG00000014682	-	100	100.000	Ursus_americanus
ENSG00000115268	RPS15	100	85.294	ENSUAMG00000021717	-	97	78.448	Ursus_americanus
ENSG00000115268	RPS15	100	85.294	ENSUMAG00000020674	-	97	78.448	Ursus_maritimus
ENSG00000115268	RPS15	99	73.134	ENSVVUG00000005571	-	80	73.913	Vulpes_vulpes
ENSG00000115268	RPS15	62	98.551	ENSVVUG00000011758	-	62	98.551	Vulpes_vulpes
ENSG00000115268	RPS15	100	100.000	ENSVVUG00000022875	-	93	80.147	Vulpes_vulpes
ENSG00000115268	RPS15	100	96.429	ENSXETG00000003706	rps15	100	95.862	Xenopus_tropicalis
ENSG00000115268	RPS15	100	95.763	ENSXCOG00000007143	rps15	99	96.350	Xiphophorus_couchianus
ENSG00000115268	RPS15	100	95.763	ENSXMAG00000013910	rps15	99	96.350	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000028	ribosomal small subunit assembly	21873635.	IBA	Process
GO:0000056	ribosomal small subunit export from nucleus	16037817.	IMP	Process
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	-	TAS	Process
GO:0001649	osteoblast differentiation	16210410.	HDA	Process
GO:0003677	DNA binding	2159154.2821540.	NAS	Function
GO:0003723	RNA binding	22658674.22681889.	HDA	Function
GO:0003735	structural constituent of ribosome	21873635.	IBA	Function
GO:0005515	protein binding	24725412.24947832.25416956.26824392.	IPI	Function
GO:0005634	nucleus	2159154.2821540.	NAS	Component
GO:0005654	nucleoplasm	16037817.	NAS	Component
GO:0005654	nucleoplasm	-	TAS	Component
GO:0005829	cytosol	-	TAS	Component
GO:0005925	focal adhesion	21423176.	HDA	Component
GO:0006364	rRNA processing	18697920.	IMP	Process
GO:0006412	translation	8706699.15883184.	IC	Process
GO:0006413	translational initiation	-	TAS	Process
GO:0006614	SRP-dependent cotranslational protein targeting to membrane	-	TAS	Process
GO:0016020	membrane	16210410.19946888.	HDA	Component
GO:0019083	viral transcription	-	TAS	Process
GO:0022627	cytosolic small ribosomal subunit	15883184.	HDA	Component
GO:0022627	cytosolic small ribosomal subunit	21873635.	IBA	Component
GO:0022627	cytosolic small ribosomal subunit	8706699.	IDA	Component
GO:0042274	ribosomal small subunit biogenesis	18697920.	IMP	Process

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
BLCA	chr19	1438452	Intron	rs757412102		0.43
BLCA	chr19	1440121	Silent	NA	K64K	0.19
BLCA	chr19	1440440	Missense_Mutation	novel	S139F	0.14
BRCA	chr19	1440093	Missense_Mutation	novel	S55C	0.4	Ribosomal_S19
COAD	chr19	1440376	Missense_Mutation	novel	E118K	0.24
COAD	chr19	1438570	Intron	novel		0.43
COAD	chr19	1438502	Intron	novel		0.34
COAD	chr19	1440148	Silent	rs753589464	P73P	0.17
GBM	chr19	1440482	3'UTR	novel		0.05
HNSC	chr19	1438476	Intron	novel		0.5
HNSC	chr19	1438393	5'UTR	novel		0.27
KIRC	chr19	1438451	Intron	novel		0.22
LGG	chr19	1438365	5'Flank	novel		0.11
LIHC	chr19	1440465	3'UTR	novel		0.46
LIHC	chr19	1438804	Splice_Region	novel		0.17
LUAD	chr19	1440454	Missense_Mutation	novel	L144V	0.21
LUSC	chr19	1438380	5'Flank	rs756348945		0.17
READ	chr19	1438538	Intron	NA		0.14
SARC	chr19	1438504	Intron	novel		0.19
SKCM	chr19	1440441	Silent	NA	S139S	0.38
SKCM	chr19	1438510	Intron	novel		0.5
SKCM	chr19	1438448	Intron	novel		0.21
SKCM	chr19	1438410	5'UTR	novel		0.29
SKCM	chr19	1440454	Missense_Mutation	NA	L144F	0.89
SKCM	chr19	1438514	Intron	novel		0.4
STAD	chr19	1440482	3'UTR	novel		0.31
STAD	chr19	1438527	Intron	novel		0.23
STAD	chr19	1440418	Missense_Mutation	novel	G132S	0.24
STAD	chr19	1438452	Intron	rs757412102		0.2
THYM	chr19	1440253	In_Frame_Ins	novel	P109dup	0.04
THYM	chr19	1440254	Splice_Site	novel	X108_splice	0.04
THYM	chr19	1440254	Splice_Site	novel	X108_splice	0.05
UCEC	chr19	1438536	Intron	rs746880057		0.4
UCEC	chr19	1438362	5'Flank	novel		0.27
UCEC	chr19	1440080	Missense_Mutation	NA	R51W	0.25	Ribosomal_S19
UCEC	chr19	1440481	3'UTR	rs770812659		0.24
UCEC	chr19	1440467	3'UTR	novel		0.39
UCEC	chr19	1440106	Silent	novel	R59R	0.12
UCEC	chr19	1440032	Nonsense_Mutation	novel	Q35*	0.12	Ribosomal_S19
UCEC	chr19	1438428	Translation_Start_Site	novel	M1?	0.06
UCEC	chr19	1440433	Missense_Mutation	novel	H137N	0.52

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
BLCA	DEL	0.223	7.2756e-08
COAD	DEL	0.1064	7.5925e-05
ESCA	DEL	0.3587	8.6035e-06
KIRP	DEL	0.0521	0.058467
LIHC	DEL	0.1865	4.7028e-08
OV	DEL	0.8584	1.3528e-139
PAAD	DEL	0.1522	0.0060878
READ	DEL	0.1273	0.23023
SKCM	DEL	0.1744	0.0059983
THCA	DEL	0.014	0.10598
UCS	DEL	0.7321	8.0449e-14

Survival Analysis

Cancer	P-value	Q-value
KIRC	0.00058	Kaplan-Meier Survival Analysis
ACC	0.00013	Kaplan-Meier Survival Analysis
BRCA	0.024	Kaplan-Meier Survival Analysis
PAAD	0.026	Kaplan-Meier Survival Analysis
BLCA	0.022	Kaplan-Meier Survival Analysis
LAML	0.02	Kaplan-Meier Survival Analysis
UCEC	0.00023	Kaplan-Meier Survival Analysis
LIHC	0.019	Kaplan-Meier Survival Analysis

Drugs

EuRBPDB

Description

RBDs

RBPome

Literatures

Expression

Transcripts

Gene Model

Pathways

PPI

Orthologs

Gene Ontology

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742