16378916 | Expression of the transcriptional coregulator FHL2 in human breast cancer: a clinicopathologic study. | J Soc Gynecol Investig | 2006 Jan | Gabriel B | - |
21377781 | FHL2 exhibits anti-proliferative and anti-apoptotic activities in liver cancer cells. | Cancer Lett | 2011 May 28 | Ng CF | doi: 10.1016/j.canlet.2011.02.001 |
19139564 | Human four-and-a-half LIM family members suppress tumor cell growth through a TGF-beta-like signaling pathway. | J Clin Invest | 2009 Feb | Ding L | doi: 10.1172/JCI35930 |
26973248 | Scaffold protein FHL2 facilitates MDM2-mediated degradation of IER3 to regulate proliferation of cervical cancer cells. | Oncogene | 2016 Sep 29 | Jin H | doi: 10.1038/onc.2016.54 |
27415427 | The four and a half LIM domains 2 (FHL2) regulates ovarian granulosa cell tumor progression via controlling AKT1 transcription. | Cell Death Dis | 2016 Jul 14 | Hua G | doi: 10.1038/cddis.2016.207. |
20734429 | Synergistic repression of estrogen receptor transcriptional activity by FHL2 and Smad4 in breast cancer cells. | IUBMB Life | 2010 Sep | Xiong Z | doi: 10.1002/iub.367. |
17682292 | FHL2 regulates cell cycle-dependent and doxorubicin-induced p21Cip1/Waf1 expression in breast cancer cells. | Cell Cycle | 2007 Jul 15 | Martin BT | - |
21826055 | FHL2 expression in peritumoural fibroblasts correlates with lymphatic metastasis in sporadic but not in HNPCC-associated colon cancer. | Lab Invest | 2011 Dec | Gullotti L | doi: 10.1038/labinvest.2011.109 |
25554651 | Tumoral expression of nuclear cofactor FHL2 is associated with lymphatic metastasis in sporadic but not in HNPCC-associated colorectal cancer. | Pathol Res Pract | 2015 Feb | Al-Nomani L | doi: 10.1016/j.prp.2014.12.001 |
20460358 | Four-and-a-half LIM protein 2 promotes invasive potential and epithelial-mesenchymal transition in colon cancer. | Carcinogenesis | 2010 Jul | Zhang W | doi: 10.1093/carcin/bgq094 |
27129278 | Mammalian Actin-binding Protein-1/Hip-55 Interacts with FHL2 and Negatively Regulates Cell Invasion. | J Biol Chem | 2016 Jul 1 | Boateng LR | doi: 10.1074/jbc.M116.725739 |
12466281 | Identification of the LIM protein FHL2 as a coactivator of beta-catenin. | J Biol Chem | 2003 Feb 14 | Wei Y | - |
26320172 | KLF8 promotes tumorigenesis, invasion and metastasis of colorectal cancer cells by transcriptional activation of FHL2. | Oncotarget | 2015 Sep 22 | Yan Q | doi: 10.18632/oncotarget.4517. |
17145880 | Androgen receptor coactivators lysine-specific histone demethylase 1 and four and a half LIM domain protein 2 predict risk of prostate cancer recurrence. | Cancer Res | 2006 Dec 1 | Kahl P | - |
23756870 | Epithelial expression of FHL2 is negatively associated with metastasis-free and overall survival in colorectal cancer. | Br J Cancer | 2013 Jul 9 | Verset L | doi: 10.1038/bjc.2013.290 |
14550570 | BRCA1 interacts with FHL2 and enhances FHL2 transactivation function. | FEBS Lett | 2003 Oct 9 | Yan J | - |
24008552 | A novel colon cancer gene therapy using rAAVmediated expression of human shRNA-FHL2. | Int J Oncol | 2013 Nov | Wu Y | doi: 10.3892/ijo.2013.2090 |
17975004 | Androgen induction of the androgen receptor coactivator four and a half LIM domain protein-2: evidence for a role for serum response factor in prostate cancer. | Cancer Res | 2007 Nov 1 | Heemers HV | - |
17192406 | Proline-, glutamic acid-, and leucine-rich protein-1/modulator of nongenomic activity of estrogen receptor enhances androgen receptor functions through LIM-only coactivator, four-and-a-half LIM-only protein 2. | Mol Endocrinol | 2007 Mar | Nair SS | - |
25917075 | LIM-only protein FHL2 critically determines survival and radioresistance of pancreatic cancer cells. | Cancer Lett | 2015 Aug 1 | Zienert E | doi: 10.1016/j.canlet.2015.04.019 |
15692560 | Suppression of FOXO1 activity by FHL2 through SIRT1-mediated deacetylation. | EMBO J | 2005 Mar 9 | Yang Y | - |
28349819 | ADAM-17/FHL2 colocalisation suggests interaction and role of these proteins in colorectal cancer. | Tumour Biol | 2017 Mar | Verset L | doi: 10.1177/1010428317695024. |
29800735 | Increased expression of FHL2 promotes tumorigenesis in cervical cancer and is correlated with poor prognosis. | Gene | 2018 Aug 30 | Jin X | doi: 10.1016/j.gene.2018.05.087 |