EuRBPDB

Description

RBDs

RBPome

Literatures

Expression

Transcripts

Gene Model

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000115677 (Gene tree)
Gene ID: 3069
Gene Symbol: HDLBP
Alias: HBP|VGL
Full Name: high density lipoprotein binding protein
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Minus strand
Length: 89,798 bases
Position: chr2:241,227,264-241,317,061
Accession: 4857
RBP type: canonical RBP
Summary: The protein encoded by this gene binds high density lipoprotein (HDL) and may function to regulate excess cholesterol levels in cells. The encoded protein also binds RNA and can induce heterochromatin formation. [provided by RefSeq, Mar 2016]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000312042	KH_1	PF00013.29	7.5e-186	1	14
ENSP00000312042	KH_1	PF00013.29	7.5e-186	2	14
ENSP00000312042	KH_1	PF00013.29	7.5e-186	3	14
ENSP00000312042	KH_1	PF00013.29	7.5e-186	4	14
ENSP00000312042	KH_1	PF00013.29	7.5e-186	5	14
ENSP00000312042	KH_1	PF00013.29	7.5e-186	6	14
ENSP00000312042	KH_1	PF00013.29	7.5e-186	7	14
ENSP00000312042	KH_1	PF00013.29	7.5e-186	8	14
ENSP00000312042	KH_1	PF00013.29	7.5e-186	9	14
ENSP00000312042	KH_1	PF00013.29	7.5e-186	10	14
ENSP00000312042	KH_1	PF00013.29	7.5e-186	11	14
ENSP00000312042	KH_1	PF00013.29	7.5e-186	12	14
ENSP00000312042	KH_1	PF00013.29	7.5e-186	13	14
ENSP00000312042	KH_1	PF00013.29	7.5e-186	14	14
ENSP00000375836	KH_1	PF00013.29	7.5e-186	1	14
ENSP00000375836	KH_1	PF00013.29	7.5e-186	2	14
ENSP00000375836	KH_1	PF00013.29	7.5e-186	3	14
ENSP00000375836	KH_1	PF00013.29	7.5e-186	4	14
ENSP00000375836	KH_1	PF00013.29	7.5e-186	5	14
ENSP00000375836	KH_1	PF00013.29	7.5e-186	6	14
ENSP00000375836	KH_1	PF00013.29	7.5e-186	7	14
ENSP00000375836	KH_1	PF00013.29	7.5e-186	8	14
ENSP00000375836	KH_1	PF00013.29	7.5e-186	9	14
ENSP00000375836	KH_1	PF00013.29	7.5e-186	10	14
ENSP00000375836	KH_1	PF00013.29	7.5e-186	11	14
ENSP00000375836	KH_1	PF00013.29	7.5e-186	12	14
ENSP00000375836	KH_1	PF00013.29	7.5e-186	13	14
ENSP00000375836	KH_1	PF00013.29	7.5e-186	14	14
ENSP00000375837	KH_1	PF00013.29	7.5e-186	1	14
ENSP00000375837	KH_1	PF00013.29	7.5e-186	2	14
ENSP00000375837	KH_1	PF00013.29	7.5e-186	3	14
ENSP00000375837	KH_1	PF00013.29	7.5e-186	4	14
ENSP00000375837	KH_1	PF00013.29	7.5e-186	5	14
ENSP00000375837	KH_1	PF00013.29	7.5e-186	6	14
ENSP00000375837	KH_1	PF00013.29	7.5e-186	7	14
ENSP00000375837	KH_1	PF00013.29	7.5e-186	8	14
ENSP00000375837	KH_1	PF00013.29	7.5e-186	9	14
ENSP00000375837	KH_1	PF00013.29	7.5e-186	10	14
ENSP00000375837	KH_1	PF00013.29	7.5e-186	11	14
ENSP00000375837	KH_1	PF00013.29	7.5e-186	12	14
ENSP00000375837	KH_1	PF00013.29	7.5e-186	13	14
ENSP00000375837	KH_1	PF00013.29	7.5e-186	14	14
ENSP00000399139	KH_1	PF00013.29	3e-174	1	13
ENSP00000399139	KH_1	PF00013.29	3e-174	2	13
ENSP00000399139	KH_1	PF00013.29	3e-174	3	13
ENSP00000399139	KH_1	PF00013.29	3e-174	4	13
ENSP00000399139	KH_1	PF00013.29	3e-174	5	13
ENSP00000399139	KH_1	PF00013.29	3e-174	6	13
ENSP00000399139	KH_1	PF00013.29	3e-174	7	13
ENSP00000399139	KH_1	PF00013.29	3e-174	8	13
ENSP00000399139	KH_1	PF00013.29	3e-174	9	13
ENSP00000399139	KH_1	PF00013.29	3e-174	10	13
ENSP00000399139	KH_1	PF00013.29	3e-174	11	13
ENSP00000399139	KH_1	PF00013.29	3e-174	12	13
ENSP00000399139	KH_1	PF00013.29	3e-174	13	13
ENSP00000362389	KH_1	PF00013.29	3.2e-151	1	11
ENSP00000362389	KH_1	PF00013.29	3.2e-151	2	11
ENSP00000362389	KH_1	PF00013.29	3.2e-151	3	11
ENSP00000362389	KH_1	PF00013.29	3.2e-151	4	11
ENSP00000362389	KH_1	PF00013.29	3.2e-151	5	11
ENSP00000362389	KH_1	PF00013.29	3.2e-151	6	11
ENSP00000362389	KH_1	PF00013.29	3.2e-151	7	11
ENSP00000362389	KH_1	PF00013.29	3.2e-151	8	11
ENSP00000362389	KH_1	PF00013.29	3.2e-151	9	11
ENSP00000362389	KH_1	PF00013.29	3.2e-151	10	11
ENSP00000362389	KH_1	PF00013.29	3.2e-151	11	11
ENSP00000405180	KH_1	PF00013.29	5.8e-52	1	3
ENSP00000405180	KH_1	PF00013.29	5.8e-52	2	3
ENSP00000405180	KH_1	PF00013.29	5.8e-52	3	3
ENSP00000388876	KH_1	PF00013.29	8.5e-51	1	3
ENSP00000388876	KH_1	PF00013.29	8.5e-51	2	3
ENSP00000388876	KH_1	PF00013.29	8.5e-51	3	3
ENSP00000393766	KH_1	PF00013.29	6.3e-49	1	3
ENSP00000393766	KH_1	PF00013.29	6.3e-49	2	3
ENSP00000393766	KH_1	PF00013.29	6.3e-49	3	3
ENSP00000405109	KH_1	PF00013.29	1.1e-17	1	1
ENSP00000403807	KH_1	PF00013.29	1.1e-17	1	1
ENSP00000411211	KH_1	PF00013.29	1.8e-12	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
22681889	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts	4SURIC & HEK293	2012 May	Baltz AG	DOI: 10.1016/j.molcel.2012.05.021
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
29431736	Capturing the interactome of newly transcribed RNA	PolyT-RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	RIC & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
22658674	Insights into RNA biology from an atlas of mammalian mRNA-binding proteins	RIC & Hela	2012 May 31	Castello A	DOI: 10.1016/j.cell.2012.04.031
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
27453046	Comprehensive Identification of RNA-Binding Domains in Human Cells	RIC & Hela	2016 Aug 18	Castello A	DOI: 10.1016/j.molcel.2016.06.029
30352994	Discovery of RNA-binding proteins and characterization of their dynamic responses by enhanced RNA interactome capture	RIC & Jurkat	2018 Oct 23	Perez-Perri JI	DOI:10.1038/s41467-018-06557-8

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
28356383	Vigilin Regulates the Expression of the Stress-Induced Ligand MICB by Interacting with Its 5' Untranslated Region.	J Immunol	2017 May 1	Berhani O	doi: 10.4049/jimmunol.1601589
9632784	In vitro genetic analysis of the RNA binding site of vigilin, a multi-KH-domain protein.	Mol Cell Biol	1998 Jul	Kanamori H	-
8681952	Two additional 5' exons in the human Vigilin gene distinguish it from the chicken gene and provide the structural basis for differential routes of gene expression.	Eur J Biochem	1996 Jun 1	Kugler S	-
8605996	Vigilin contains a functional nuclear localisation sequence and is present in both the cytoplasm and the nucleus.	FEBS Lett	1996 Mar 18	Kugler S	-
11713986	A family of IGF-II mRNA binding proteins (IMP) involved in RNA trafficking.	Scand J Clin Lab Invest Suppl	2001	Nielsen FC	-
11050168	Vigilin binding selectively inhibits cleavage of the vitellogenin mRNA 3'-untranslated region by the mRNA endonuclease polysomal ribonuclease 1.	Proc Natl Acad Sci U S A	2000 Nov 7	Cunningham KS	-
18648073	On the mechanism of induction of heterochromatin by the RNA-binding protein vigilin.	RNA	2008 Sep	Zhou J	doi: 10.1261/rna.1036308
22607704	Vigilin interacts with signal peptide peptidase.	Proteome Sci	2012 May 18	Lu SH	doi: 10.1186/1477-5956-10-33.
25129143	Human somatic cell mutagenesis creates genetically tractable sarcomas.	Nat Genet	2014 Sep	Molyneux SD	doi: 10.1038/ng.3065
24676454	Vigilin is overexpressed in hepatocellular carcinoma and is required for HCC cell proliferation and tumor growth.	Oncol Rep	2014 May	Yang WL	doi: 10.3892/or.2014.3111
27665711	The RNA-binding protein vigilin regulates VLDL secretion through modulation of Apob mRNA translation.	Nat Commun	2016 Sep 26	Mobin MB	doi: 10.1038/ncomms12848.
28576776	RNA Binding Protein Vigilin Collaborates with miRNAs To Regulate Gene Expression for Caenorhabditis elegans Larval Development.	G3 (Bethesda)	2017 Aug 7	Zabinsky RA	doi: 10.1534/g3.117.043414.
28975734	A jack of all trades: the RNA-binding protein vigilin.	Wiley Interdiscip Rev RNA	2017 Nov	Cheng MH	doi: 10.1002/wrna.1448
29972781	The RNA-Binding Protein Scp160p Facilitates Aggregation of Many Endogenous Q/N-Rich Proteins.	Cell Rep	2018 Jul 3	Cheng MHK	doi: 10.1016/j.celrep.2018.06.015.
16448619	Analysis of RNA-protein interactions by a microplate-based fluorescence anisotropy assay.	Anal Biochem	2006 Mar 15	Mao C	-
14618268	The multi-KH protein vigilin associates with free and membrane-bound ribosomes.	Cell Mol Life Sci	2003 Oct	Kruse C	-
14500828	RNAi-mediated depletion of the 15 KH domain protein, vigilin, induces death of dividing and non-dividing human cells but does not initially inhibit protein synthesis.	Nucleic Acids Res	2003 Oct 1	Goolsby KM	-

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000449864	HDLBP-223	529	-	ENSP00000396202	36 (aa)	-	C9JE93
ENST00000420451	HDLBP-207	559	-	ENSP00000403693	69 (aa)	-	C9JBS3
ENST00000452931	HDLBP-225	801	-	ENSP00000388876	267 (aa)	-	H7BZC3
ENST00000373292	HDLBP-202	3297	-	ENSP00000362389	973 (aa)	-	H0Y394
ENST00000442714	HDLBP-219	569	-	ENSP00000413891	128 (aa)	-	C9JK79
ENST00000422080	HDLBP-208	578	-	ENSP00000409868	53 (aa)	-	C9JQ82
ENST00000488013	HDLBP-242	651	-	-	- (aa)	-	-
ENST00000460826	HDLBP-229	442	-	-	- (aa)	-	-
ENST00000442730	HDLBP-220	683	-	ENSP00000411211	126 (aa)	-	H7C3D0
ENST00000470482	HDLBP-232	624	-	-	- (aa)	-	-
ENST00000494862	HDLBP-245	356	-	-	- (aa)	-	-
ENST00000471294	HDLBP-234	490	-	-	- (aa)	-	-
ENST00000452065	HDLBP-224	996	-	ENSP00000387782	164 (aa)	-	C9JZI8
ENST00000470710	HDLBP-233	578	-	-	- (aa)	-	-
ENST00000496569	HDLBP-246	374	-	-	- (aa)	-	-
ENST00000467435	HDLBP-231	639	-	-	- (aa)	-	-
ENST00000430918	HDLBP-217	612	-	ENSP00000403913	141 (aa)	-	C9JHZ8
ENST00000459788	HDLBP-228	563	-	-	- (aa)	-	-
ENST00000427183	HDLBP-214	6238	-	ENSP00000399139	1235 (aa)	-	Q00341
ENST00000422933	HDLBP-209	929	-	ENSP00000403807	224 (aa)	-	C9JIZ1
ENST00000453141	HDLBP-226	997	-	ENSP00000393766	332 (aa)	-	H7C0A4
ENST00000462130	HDLBP-230	464	-	-	- (aa)	-	-
ENST00000487169	HDLBP-241	4339	-	-	- (aa)	-	-
ENST00000476807	HDLBP-235	1070	-	-	- (aa)	-	-
ENST00000310931	HDLBP-201	4571	XM_005247002	ENSP00000312042	1268 (aa)	XP_005247059	A0A024R4E5
ENST00000427007	HDLBP-213	459	-	ENSP00000397799	19 (aa)	-	C9J739
ENST00000483086	HDLBP-239	620	-	-	- (aa)	-	-
ENST00000423693	HDLBP-210	544	-	ENSP00000413805	81 (aa)	-	C9JHN6
ENST00000477477	HDLBP-236	340	-	-	- (aa)	-	-
ENST00000498595	HDLBP-247	595	-	-	- (aa)	-	-
ENST00000425989	HDLBP-211	530	-	ENSP00000390942	79 (aa)	-	C9JEJ8
ENST00000391975	HDLBP-203	6372	XM_006712475	ENSP00000375836	1268 (aa)	XP_006712538	A0A024R4E5
ENST00000391976	HDLBP-204	4489	XM_017003942	ENSP00000375837	1268 (aa)	XP_016859431	A0A024R4E5
ENST00000413241	HDLBP-205	581	-	ENSP00000390290	81 (aa)	-	C9JHN6
ENST00000428482	HDLBP-216	1096	-	ENSP00000405109	221 (aa)	-	C9J5E5
ENST00000479169	HDLBP-237	1017	-	-	- (aa)	-	-
ENST00000449504	HDLBP-222	566	-	ENSP00000396959	17 (aa)	-	C9JHS9
ENST00000417540	HDLBP-206	525	-	ENSP00000391773	14 (aa)	-	C9JB08
ENST00000488923	HDLBP-243	582	-	-	- (aa)	-	-
ENST00000441124	HDLBP-218	708	-	ENSP00000396964	126 (aa)	-	C9JHS7
ENST00000479894	HDLBP-238	840	-	-	- (aa)	-	-
ENST00000484412	HDLBP-240	669	-	-	- (aa)	-	-
ENST00000427487	HDLBP-215	924	-	ENSP00000405180	308 (aa)	-	H7C2D1
ENST00000458564	HDLBP-227	420	-	ENSP00000408582	46 (aa)	-	C9JMQ6
ENST00000426343	HDLBP-212	594	-	ENSP00000394205	96 (aa)	-	C9JT62
ENST00000490697	HDLBP-244	581	-	-	- (aa)	-	-
ENST00000444092	HDLBP-221	598	-	ENSP00000416559	147 (aa)	-	C9JES8

Gene Model

Click here to download ENSG00000115677's gene model file

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000115677	Fibrinogen	2E-14	28107422
ENSG00000115677	Leukemia, Lymphocytic, Chronic, B-Cell	8E-8	26956414
ENSG00000115677	Fibrinogen	8E-19	26561523

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000115677	rs113492892	2	241236980	G	Intraocular pressure	29617998	[0.059-0.122] unit increase	0.0906	EFO_0004695
ENSG00000115677	rs7578199	2	241253433	T	Chronic lymphocytic leukemia	26956414	[1.11-1.25]	1.1764705	EFO_0000095
ENSG00000115677	rs59104589	2	241298487	T	Fibrinogen levels	26561523	NR unit decrease	0.0083	EFO_0004623
ENSG00000115677	rs59104589	2	241298487	?	Fibrinogen levels	28107422	unit increase	0.0081	EFO_0004623
ENSG00000115677	rs6743226	2	241297557	C	Waist circumference adjusted for BMI (adjusted for smoking behaviour)	28443625	[0.012-0.024] unit increase	0.018	EFO_0004318\|EFO_0007789
ENSG00000115677	rs6743226	2	241297557	C	Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction)	28443625			EFO_0004318\|EFO_0007789
ENSG00000115677	rs6743226	2	241297557	C	Waist circumference adjusted for BMI in non-smokers	28443625	[0.013-0.025] unit increase	0.019	EFO_0007789
ENSG00000115677	rs1134941	2	241315963	?	Balding type 1	30595370			EFO_0007825
ENSG00000115677	rs1134941	2	241315963	A	Male-pattern baldness	30573740	[0.02-0.032] unit increase	0.0260636	EFO_0007825
ENSG00000115677	rs75590598	2	241246239	?	Eosinophil counts	30595370			EFO_0004842

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000115677's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000115677	HDLBP	98	82.625	ENSAPOG00000012609	hdlbpa	99	79.405	Acanthochromis_polyacanthus
ENSG00000115677	HDLBP	100	100.000	ENSAMEG00000016552	HDLBP	100	97.089	Ailuropoda_melanoleuca
ENSG00000115677	HDLBP	98	84.170	ENSACIG00000006015	hdlbpa	99	77.788	Amphilophus_citrinellus
ENSG00000115677	HDLBP	98	83.012	ENSAOCG00000000300	hdlbpa	99	79.405	Amphiprion_ocellaris
ENSG00000115677	HDLBP	98	82.625	ENSAPEG00000000522	hdlbpa	99	80.268	Amphiprion_percula
ENSG00000115677	HDLBP	100	81.498	ENSATEG00000009748	hdlbpa	99	79.248	Anabas_testudineus
ENSG00000115677	HDLBP	100	100.000	ENSACAG00000001556	HDLBP	100	89.117	Anolis_carolinensis
ENSG00000115677	HDLBP	100	100.000	ENSANAG00000020545	HDLBP	100	98.738	Aotus_nancymaae
ENSG00000115677	HDLBP	98	83.784	ENSACLG00000025965	hdlbpa	99	79.248	Astatotilapia_calliptera
ENSG00000115677	HDLBP	97	84.556	ENSAMXG00000004221	hdlbpa	99	80.236	Astyanax_mexicanus
ENSG00000115677	HDLBP	100	100.000	ENSBTAG00000004315	HDLBP	100	95.899	Bos_taurus
ENSG00000115677	HDLBP	100	100.000	ENSCJAG00000006152	HDLBP	100	98.583	Callithrix_jacchus
ENSG00000115677	HDLBP	100	100.000	ENSCAFG00000012913	HDLBP	100	97.451	Canis_familiaris
ENSG00000115677	HDLBP	100	100.000	ENSCAFG00020025089	HDLBP	100	97.397	Canis_lupus_dingo
ENSG00000115677	HDLBP	100	100.000	ENSCHIG00000022364	HDLBP	100	95.899	Capra_hircus
ENSG00000115677	HDLBP	100	100.000	ENSTSYG00000002379	HDLBP	100	98.028	Carlito_syrichta
ENSG00000115677	HDLBP	100	100.000	ENSCAPG00000008584	HDLBP	100	92.587	Cavia_aperea
ENSG00000115677	HDLBP	100	100.000	ENSCPOG00000006297	HDLBP	100	97.003	Cavia_porcellus
ENSG00000115677	HDLBP	99	80.782	ENSCCAG00000037920	-	95	80.782	Cebus_capucinus
ENSG00000115677	HDLBP	100	100.000	ENSCCAG00000023361	-	100	98.896	Cebus_capucinus
ENSG00000115677	HDLBP	100	100.000	ENSCATG00000039363	HDLBP	100	99.685	Cercocebus_atys
ENSG00000115677	HDLBP	100	100.000	ENSCLAG00000002365	HDLBP	100	97.161	Chinchilla_lanigera
ENSG00000115677	HDLBP	100	100.000	ENSCSAG00000005781	HDLBP	100	98.212	Chlorocebus_sabaeus
ENSG00000115677	HDLBP	88	96.465	ENSCHOG00000003882	-	100	66.382	Choloepus_hoffmanni
ENSG00000115677	HDLBP	100	100.000	ENSCPBG00000002442	HDLBP	100	88.880	Chrysemys_picta_bellii
ENSG00000115677	HDLBP	100	100.000	ENSCANG00000033571	HDLBP	100	99.448	Colobus_angolensis_palliatus
ENSG00000115677	HDLBP	100	100.000	ENSCGRG00001006086	Hdlbp	100	97.792	Cricetulus_griseus_chok1gshd
ENSG00000115677	HDLBP	99	51.327	ENSCGRG00001010570	4921511C20Rik	100	50.171	Cricetulus_griseus_chok1gshd
ENSG00000115677	HDLBP	99	55.906	ENSCGRG00000015720	Gm382	98	53.281	Cricetulus_griseus_crigri
ENSG00000115677	HDLBP	100	100.000	ENSCGRG00000014444	Hdlbp	100	97.792	Cricetulus_griseus_crigri
ENSG00000115677	HDLBP	96	84.556	ENSCSEG00000008853	hdlbpa	99	78.650	Cynoglossus_semilaevis
ENSG00000115677	HDLBP	100	82.667	ENSCVAG00000017892	hdlbpa	99	78.650	Cyprinodon_variegatus
ENSG00000115677	HDLBP	97	84.942	ENSDARG00000009830	hdlbpa	100	79.954	Danio_rerio
ENSG00000115677	HDLBP	100	100.000	ENSDNOG00000006753	HDLBP	100	94.187	Dasypus_novemcinctus
ENSG00000115677	HDLBP	100	100.000	ENSDORG00000028840	-	100	96.629	Dipodomys_ordii
ENSG00000115677	HDLBP	99	97.297	ENSETEG00000005416	-	79	92.793	Echinops_telfairi
ENSG00000115677	HDLBP	100	100.000	ENSEASG00005008249	HDLBP	100	97.792	Equus_asinus_asinus
ENSG00000115677	HDLBP	99	57.942	ENSECAG00000028723	-	99	55.490	Equus_caballus
ENSG00000115677	HDLBP	100	100.000	ENSECAG00000012829	HDLBP	100	97.792	Equus_caballus
ENSG00000115677	HDLBP	98	59.843	ENSECAG00000030885	-	99	56.300	Equus_caballus
ENSG00000115677	HDLBP	96	96.850	ENSEEUG00000014648	HDLBP	90	96.850	Erinaceus_europaeus
ENSG00000115677	HDLBP	99	83.012	ENSELUG00000010700	hdlbpa	99	77.434	Esox_lucius
ENSG00000115677	HDLBP	100	100.000	ENSFCAG00000010455	HDLBP	100	97.476	Felis_catus
ENSG00000115677	HDLBP	100	100.000	ENSFALG00000003437	HDLBP	100	91.009	Ficedula_albicollis
ENSG00000115677	HDLBP	100	100.000	ENSFDAG00000000456	HDLBP	100	96.924	Fukomys_damarensis
ENSG00000115677	HDLBP	99	82.625	ENSFHEG00000004848	hdlbpa	99	78.370	Fundulus_heteroclitus
ENSG00000115677	HDLBP	99	81.853	ENSGMOG00000009932	hdlbpa	99	77.308	Gadus_morhua
ENSG00000115677	HDLBP	100	100.000	ENSGALG00000005823	HDLBP	100	90.852	Gallus_gallus
ENSG00000115677	HDLBP	100	83.036	ENSGAFG00000016766	hdlbpa	84	78.470	Gambusia_affinis
ENSG00000115677	HDLBP	100	81.057	ENSGACG00000004648	hdlbpa	99	77.508	Gasterosteus_aculeatus
ENSG00000115677	HDLBP	100	100.000	ENSGAGG00000004256	HDLBP	100	91.404	Gopherus_agassizii
ENSG00000115677	HDLBP	100	100.000	ENSGGOG00000004392	HDLBP	100	99.921	Gorilla_gorilla
ENSG00000115677	HDLBP	98	83.784	ENSHBUG00000001136	hdlbpa	99	79.248	Haplochromis_burtoni
ENSG00000115677	HDLBP	100	100.000	ENSHGLG00000004910	HDLBP	100	96.215	Heterocephalus_glaber_female
ENSG00000115677	HDLBP	100	100.000	ENSHGLG00100013326	HDLBP	100	98.315	Heterocephalus_glaber_male
ENSG00000115677	HDLBP	99	82.625	ENSHCOG00000014837	hdlbpa	99	78.410	Hippocampus_comes
ENSG00000115677	HDLBP	97	84.942	ENSIPUG00000013088	hdlbp	99	78.866	Ictalurus_punctatus
ENSG00000115677	HDLBP	92	76.000	ENSIPUG00000013177	-	91	76.000	Ictalurus_punctatus
ENSG00000115677	HDLBP	100	100.000	ENSSTOG00000013331	HDLBP	100	96.688	Ictidomys_tridecemlineatus
ENSG00000115677	HDLBP	100	100.000	ENSJJAG00000003596	Hdlbp	100	98.028	Jaculus_jaculus
ENSG00000115677	HDLBP	96	48.235	ENSJJAG00000013712	-	96	45.598	Jaculus_jaculus
ENSG00000115677	HDLBP	98	83.784	ENSKMAG00000007571	hdlbpa	99	78.980	Kryptolebias_marmoratus
ENSG00000115677	HDLBP	99	82.239	ENSLBEG00000027461	hdlbpa	99	78.894	Labrus_bergylta
ENSG00000115677	HDLBP	100	100.000	ENSLACG00000003592	HDLBP	99	84.301	Latimeria_chalumnae
ENSG00000115677	HDLBP	97	86.486	ENSLOCG00000006278	hdlbpa	99	80.627	Lepisosteus_oculatus
ENSG00000115677	HDLBP	100	100.000	ENSLAFG00000014826	HDLBP	100	96.451	Loxodonta_africana
ENSG00000115677	HDLBP	100	100.000	ENSMFAG00000033641	HDLBP	100	99.685	Macaca_fascicularis
ENSG00000115677	HDLBP	100	100.000	ENSMMUG00000004730	HDLBP	100	99.290	Macaca_mulatta
ENSG00000115677	HDLBP	100	100.000	ENSMNEG00000024260	HDLBP	100	99.685	Macaca_nemestrina
ENSG00000115677	HDLBP	100	100.000	ENSMLEG00000042734	HDLBP	100	99.685	Mandrillus_leucophaeus
ENSG00000115677	HDLBP	98	83.398	ENSMAMG00000008611	hdlbpa	99	79.170	Mastacembelus_armatus
ENSG00000115677	HDLBP	98	83.784	ENSMZEG00005009513	hdlbpa	99	79.248	Maylandia_zebra
ENSG00000115677	HDLBP	100	100.000	ENSMGAG00000003686	HDLBP	100	91.078	Meleagris_gallopavo
ENSG00000115677	HDLBP	100	100.000	ENSMAUG00000017743	Hdlbp	100	97.792	Mesocricetus_auratus
ENSG00000115677	HDLBP	100	100.000	ENSMICG00000004569	HDLBP	100	97.319	Microcebus_murinus
ENSG00000115677	HDLBP	100	100.000	ENSMOCG00000006679	Hdlbp	100	97.950	Microtus_ochrogaster
ENSG00000115677	HDLBP	100	82.222	ENSMMOG00000006880	hdlbpa	99	74.879	Mola_mola
ENSG00000115677	HDLBP	100	100.000	ENSMODG00000016033	HDLBP	100	92.019	Monodelphis_domestica
ENSG00000115677	HDLBP	97	84.170	ENSMALG00000015095	hdlbpa	99	78.638	Monopterus_albus
ENSG00000115677	HDLBP	99	53.097	MGP_CAROLIEiJ_G0033374	4921511C20Rik	100	50.512	Mus_caroli
ENSG00000115677	HDLBP	99	54.724	MGP_CAROLIEiJ_G0033373	Gm382	96	50.939	Mus_caroli
ENSG00000115677	HDLBP	100	100.000	MGP_CAROLIEiJ_G0014456	Hdlbp	100	98.315	Mus_caroli
ENSG00000115677	HDLBP	99	53.097	ENSMUSG00000049815	4921511C20Rik	100	50.512	Mus_musculus
ENSG00000115677	HDLBP	99	53.937	ENSMUSG00000062791	Gm382	94	50.496	Mus_musculus
ENSG00000115677	HDLBP	100	100.000	ENSMUSG00000034088	Hdlbp	100	98.315	Mus_musculus
ENSG00000115677	HDLBP	99	51.327	MGP_PahariEiJ_G0031914	4921511C20Rik	100	49.829	Mus_pahari
ENSG00000115677	HDLBP	99	54.331	MGP_PahariEiJ_G0031913	Gm382	94	51.378	Mus_pahari
ENSG00000115677	HDLBP	100	100.000	MGP_PahariEiJ_G0027692	Hdlbp	100	98.315	Mus_pahari
ENSG00000115677	HDLBP	100	100.000	MGP_SPRETEiJ_G0015260	Hdlbp	100	98.315	Mus_spretus
ENSG00000115677	HDLBP	99	53.543	MGP_SPRETEiJ_G0034538	Gm382	95	50.055	Mus_spretus
ENSG00000115677	HDLBP	99	52.212	MGP_SPRETEiJ_G0034539	4921511C20Rik	100	50.512	Mus_spretus
ENSG00000115677	HDLBP	100	100.000	ENSMPUG00000000163	HDLBP	100	96.845	Mustela_putorius_furo
ENSG00000115677	HDLBP	100	100.000	ENSMLUG00000005628	HDLBP	100	97.319	Myotis_lucifugus
ENSG00000115677	HDLBP	100	100.000	ENSNGAG00000014873	Hdlbp	100	97.792	Nannospalax_galili
ENSG00000115677	HDLBP	98	83.784	ENSNBRG00000000051	hdlbpa	98	79.887	Neolamprologus_brichardi
ENSG00000115677	HDLBP	100	100.000	ENSNLEG00000031018	-	99	93.238	Nomascus_leucogenys
ENSG00000115677	HDLBP	100	100.000	ENSNLEG00000013818	HDLBP	100	99.685	Nomascus_leucogenys
ENSG00000115677	HDLBP	100	100.000	ENSMEUG00000008427	HDLBP	88	92.491	Notamacropus_eugenii
ENSG00000115677	HDLBP	100	100.000	ENSOPRG00000011965	-	100	91.246	Ochotona_princeps
ENSG00000115677	HDLBP	100	100.000	ENSODEG00000012313	-	100	96.688	Octodon_degus
ENSG00000115677	HDLBP	100	100.000	ENSODEG00000017391	-	100	90.773	Octodon_degus
ENSG00000115677	HDLBP	98	83.398	ENSONIG00000019272	hdlbpa	99	79.092	Oreochromis_niloticus
ENSG00000115677	HDLBP	100	100.000	ENSOANG00000011759	-	100	92.435	Ornithorhynchus_anatinus
ENSG00000115677	HDLBP	62	93.662	ENSOANG00000021864	-	99	93.525	Ornithorhynchus_anatinus
ENSG00000115677	HDLBP	100	100.000	ENSOCUG00000012667	HDLBP	100	96.609	Oryctolagus_cuniculus
ENSG00000115677	HDLBP	100	81.057	ENSORLG00000002226	hdlbpa	99	78.072	Oryzias_latipes
ENSG00000115677	HDLBP	100	81.057	ENSORLG00020007905	hdlbpa	97	81.311	Oryzias_latipes_hni
ENSG00000115677	HDLBP	98	83.071	ENSORLG00015004126	hdlbpa	99	78.227	Oryzias_latipes_hsok
ENSG00000115677	HDLBP	100	81.778	ENSOMEG00000000247	hdlbpa	99	78.933	Oryzias_melastigma
ENSG00000115677	HDLBP	100	100.000	ENSOGAG00000000738	HDLBP	100	97.082	Otolemur_garnettii
ENSG00000115677	HDLBP	100	100.000	ENSOARG00000017870	HDLBP	100	93.961	Ovis_aries
ENSG00000115677	HDLBP	100	100.000	ENSPPAG00000023318	HDLBP	100	99.763	Pan_paniscus
ENSG00000115677	HDLBP	100	100.000	ENSPPRG00000010215	HDLBP	100	97.555	Panthera_pardus
ENSG00000115677	HDLBP	100	100.000	ENSPTIG00000009328	HDLBP	97	98.489	Panthera_tigris_altaica
ENSG00000115677	HDLBP	100	100.000	ENSPTRG00000013121	HDLBP	100	99.842	Pan_troglodytes
ENSG00000115677	HDLBP	100	100.000	ENSPANG00000011832	HDLBP	100	99.527	Papio_anubis
ENSG00000115677	HDLBP	99	84.942	ENSPKIG00000002392	hdlbpa	99	78.795	Paramormyrops_kingsleyae
ENSG00000115677	HDLBP	100	100.000	ENSPSIG00000010068	HDLBP	100	90.259	Pelodiscus_sinensis
ENSG00000115677	HDLBP	98	83.784	ENSPMGG00000002102	hdlbpa	99	78.488	Periophthalmus_magnuspinnatus
ENSG00000115677	HDLBP	100	100.000	ENSPEMG00000017704	Hdlbp	100	98.107	Peromyscus_maniculatus_bairdii
ENSG00000115677	HDLBP	100	100.000	ENSPCIG00000015375	HDLBP	94	92.789	Phascolarctos_cinereus
ENSG00000115677	HDLBP	100	82.379	ENSPFOG00000000236	hdlbpa	99	78.292	Poecilia_formosa
ENSG00000115677	HDLBP	100	82.743	ENSPLAG00000006033	hdlbpa	100	79.370	Poecilia_latipinna
ENSG00000115677	HDLBP	100	83.036	ENSPMEG00000006627	hdlbpa	99	78.448	Poecilia_mexicana
ENSG00000115677	HDLBP	100	83.036	ENSPREG00000014450	hdlbpa	82	79.828	Poecilia_reticulata
ENSG00000115677	HDLBP	100	100.000	ENSPPYG00000013351	HDLBP	100	99.448	Pongo_abelii
ENSG00000115677	HDLBP	100	100.000	ENSPCAG00000011136	HDLBP	79	91.860	Procavia_capensis
ENSG00000115677	HDLBP	100	100.000	ENSPCOG00000021622	HDLBP	100	97.248	Propithecus_coquereli
ENSG00000115677	HDLBP	100	100.000	ENSPVAG00000000555	HDLBP	100	95.189	Pteropus_vampyrus
ENSG00000115677	HDLBP	98	83.784	ENSPNYG00000020753	hdlbpa	99	79.327	Pundamilia_nyererei
ENSG00000115677	HDLBP	99	85.328	ENSPNAG00000029610	hdlbpa	99	76.845	Pygocentrus_nattereri
ENSG00000115677	HDLBP	99	54.331	ENSRNOG00000031294	RGD1563104	97	52.035	Rattus_norvegicus
ENSG00000115677	HDLBP	99	46.960	ENSRNOG00000042823	RGD1561230	97	46.960	Rattus_norvegicus
ENSG00000115677	HDLBP	100	100.000	ENSRNOG00000031479	Hdlbp	100	97.871	Rattus_norvegicus
ENSG00000115677	HDLBP	96	58.025	ENSRNOG00000028847	AABR07040251.1	100	50.575	Rattus_norvegicus
ENSG00000115677	HDLBP	100	100.000	ENSRBIG00000041381	HDLBP	100	99.527	Rhinopithecus_bieti
ENSG00000115677	HDLBP	100	100.000	ENSRROG00000034263	HDLBP	100	99.527	Rhinopithecus_roxellana
ENSG00000115677	HDLBP	100	100.000	ENSSBOG00000029714	-	99	99.174	Saimiri_boliviensis_boliviensis
ENSG00000115677	HDLBP	99	88.417	ENSSBOG00000033067	-	96	85.776	Saimiri_boliviensis_boliviensis
ENSG00000115677	HDLBP	100	100.000	ENSSHAG00000012422	HDLBP	100	93.849	Sarcophilus_harrisii
ENSG00000115677	HDLBP	99	84.170	ENSSFOG00015018627	hdlbp	99	79.781	Scleropages_formosus
ENSG00000115677	HDLBP	98	83.784	ENSSMAG00000002382	hdlbpa	99	79.316	Scophthalmus_maximus
ENSG00000115677	HDLBP	100	82.222	ENSSDUG00000022258	hdlbpa	99	79.124	Seriola_dumerili
ENSG00000115677	HDLBP	100	82.222	ENSSLDG00000004437	hdlbpa	99	79.046	Seriola_lalandi_dorsalis
ENSG00000115677	HDLBP	100	100.000	ENSSARG00000012639	HDLBP	100	77.997	Sorex_araneus
ENSG00000115677	HDLBP	100	100.000	ENSSPUG00000009182	HDLBP	100	90.221	Sphenodon_punctatus
ENSG00000115677	HDLBP	100	80.263	ENSSPAG00000009145	hdlbpa	99	78.795	Stegastes_partitus
ENSG00000115677	HDLBP	100	100.000	ENSSSCG00000016379	HDLBP	100	95.582	Sus_scrofa
ENSG00000115677	HDLBP	100	100.000	ENSTGUG00000006189	HDLBP	100	90.926	Taeniopygia_guttata
ENSG00000115677	HDLBP	98	82.625	ENSTRUG00000012148	hdlbpa	99	77.690	Takifugu_rubripes
ENSG00000115677	HDLBP	98	83.398	ENSTNIG00000004185	hdlbpa	100	77.937	Tetraodon_nigroviridis
ENSG00000115677	HDLBP	100	100.000	ENSTBEG00000001860	HDLBP	95	76.010	Tupaia_belangeri
ENSG00000115677	HDLBP	100	100.000	ENSTTRG00000015251	HDLBP	77	97.227	Tursiops_truncatus
ENSG00000115677	HDLBP	100	100.000	ENSUAMG00000018383	HDLBP	100	97.476	Ursus_americanus
ENSG00000115677	HDLBP	100	100.000	ENSUMAG00000010539	HDLBP	100	97.397	Ursus_maritimus
ENSG00000115677	HDLBP	99	61.151	ENSVPAG00000003112	HDLBP	93	61.062	Vicugna_pacos
ENSG00000115677	HDLBP	100	100.000	ENSVVUG00000022797	HDLBP	99	97.498	Vulpes_vulpes
ENSG00000115677	HDLBP	96	87.645	ENSXETG00000012164	hdlbp	99	83.216	Xenopus_tropicalis
ENSG00000115677	HDLBP	100	82.589	ENSXCOG00000005943	hdlbpa	99	78.319	Xiphophorus_couchianus
ENSG00000115677	HDLBP	98	82.625	ENSXMAG00000003787	hdlbpa	99	77.925	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0003723	RNA binding	22658674.22681889.	HDA	Function
GO:0005515	protein binding	24725430.	IPI	Function
GO:0005634	nucleus	-	IEA	Component
GO:0005829	cytosol	-	IDA	Component
GO:0005886	plasma membrane	-	TAS	Component
GO:0006869	lipid transport	-	IEA	Process
GO:0008203	cholesterol metabolic process	-	IEA	Process
GO:0008289	lipid binding	1318310.	TAS	Function
GO:0034364	high-density lipoprotein particle	-	IEA	Component
GO:0034384	high-density lipoprotein particle clearance	-	TAS	Process
GO:0045296	cadherin binding	25468996.	HDA	Function