EuRBPDB

Description

RBDs

RBPome

Literatures

Expression

Transcripts

Gene Model

Phenotypes

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000115816 (Gene tree)
Gene ID: 10153
Gene Symbol: CEBPZ
Alias: CBF2|CTF2
Full Name: CCAAT enhancer binding protein zeta
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Minus strand
Length: 30,102 bases
Position: chr2:37,201,612-37,231,713
Accession: 24218
RBP type: canonical RBP
Summary: This gene belongs to the CEBP family. The encoded protein plays a role in cellular response to environmental stimuli through a transcriptional process that involves heat shock factors, conserved DNA elements (heat shock elements or HSEs) and CCAAT boxes. The protein acts as a DNA-binding transcriptional activator and regulates the heat-shock protein 70 (HSP70) promoter in a CCAAT-dependent manner. The protein is also involved in cell growth and differentiation, particularly, hematopoietic differentiation. Methylation of the promoter of this gene or mutations within the gene may be correlated with occurance of acute myeloid leukemia (AML). [provided by RefSeq, Jun 2016]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000234170	CBF	PF03914.17	5.7e-56	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
22681889	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts	4SURIC & HEK293	2012 May	Baltz AG	DOI: 10.1016/j.molcel.2012.05.021
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
29431736	Capturing the interactome of newly transcribed RNA	PolyT-RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	RIC & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
22658674	Insights into RNA biology from an atlas of mammalian mRNA-binding proteins	RIC & Hela	2012 May 31	Castello A	DOI: 10.1016/j.cell.2012.04.031
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30352994	Discovery of RNA-binding proteins and characterization of their dynamic responses by enhanced RNA interactome capture	RIC & Jurkat	2018 Oct 23	Perez-Perri JI	DOI:10.1038/s41467-018-06557-8

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
31217256	Rrp5 Establishes a Checkpoint for 60S Assembly During 40S Maturation.	RNA	2019 Jun 19	Khoshnevis S	doi: 10.1261/rna.071225.119

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000489306	CEBPZ-203	611	-	-	- (aa)	-	-
ENST00000234170	CEBPZ-201	3463	-	ENSP00000234170	1054 (aa)	-	Q03701
ENST00000446769	CEBPZ-202	526	-	ENSP00000391881	146 (aa)	-	C9J9W7

Gene Model

Click here to download ENSG00000115816's gene model file

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000115816	Child Development Disorders, Pervasive	1.9444000E-005	-

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000115816's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000115816	CEBPZ	98	56.744	ENSAPOG00000010013	cebpz	92	58.664	Acanthochromis_polyacanthus
ENSG00000115816	CEBPZ	100	87.336	ENSAMEG00000017580	CEBPZ	100	87.336	Ailuropoda_melanoleuca
ENSG00000115816	CEBPZ	89	58.809	ENSACIG00000014854	cebpz	92	54.925	Amphilophus_citrinellus
ENSG00000115816	CEBPZ	95	58.229	ENSAOCG00000007301	cebpz	92	59.223	Amphiprion_ocellaris
ENSG00000115816	CEBPZ	95	58.037	ENSAPEG00000014644	cebpz	92	58.932	Amphiprion_percula
ENSG00000115816	CEBPZ	97	54.728	ENSATEG00000001538	cebpz	92	56.324	Anabas_testudineus
ENSG00000115816	CEBPZ	94	62.963	ENSAPLG00000014239	CEBPZ	97	63.454	Anas_platyrhynchos
ENSG00000115816	CEBPZ	96	63.865	ENSACAG00000001411	CEBPZ	96	65.059	Anolis_carolinensis
ENSG00000115816	CEBPZ	100	95.161	ENSANAG00000030775	CEBPZ	100	95.161	Aotus_nancymaae
ENSG00000115816	CEBPZ	93	57.283	ENSACLG00000006896	cebpz	93	58.171	Astatotilapia_calliptera
ENSG00000115816	CEBPZ	96	57.309	ENSAMXG00000018270	cebpz	93	58.974	Astyanax_mexicanus
ENSG00000115816	CEBPZ	100	84.354	ENSBTAG00000039770	CEBPZ	99	84.166	Bos_taurus
ENSG00000115816	CEBPZ	64	34.335	WBGene00009084	F23B12.7	81	34.518	Caenorhabditis_elegans
ENSG00000115816	CEBPZ	98	93.706	ENSCJAG00000003858	CEBPZ	99	94.308	Callithrix_jacchus
ENSG00000115816	CEBPZ	100	87.054	ENSCAFG00000006085	CEBPZ	100	87.054	Canis_familiaris
ENSG00000115816	CEBPZ	100	87.488	ENSCAFG00020022832	CEBPZ	100	87.488	Canis_lupus_dingo
ENSG00000115816	CEBPZ	100	84.449	ENSCHIG00000020789	CEBPZ	100	84.166	Capra_hircus
ENSG00000115816	CEBPZ	100	87.913	ENSTSYG00000005691	CEBPZ	100	87.913	Carlito_syrichta
ENSG00000115816	CEBPZ	95	78.020	ENSCAPG00000017127	CEBPZ	100	78.020	Cavia_aperea
ENSG00000115816	CEBPZ	100	82.109	ENSCPOG00000020778	CEBPZ	100	82.015	Cavia_porcellus
ENSG00000115816	CEBPZ	100	94.402	ENSCCAG00000036968	CEBPZ	100	94.402	Cebus_capucinus
ENSG00000115816	CEBPZ	100	96.300	ENSCATG00000030450	CEBPZ	100	96.300	Cercocebus_atys
ENSG00000115816	CEBPZ	100	84.731	ENSCLAG00000009453	CEBPZ	100	84.637	Chinchilla_lanigera
ENSG00000115816	CEBPZ	100	96.300	ENSCSAG00000012188	CEBPZ	100	96.300	Chlorocebus_sabaeus
ENSG00000115816	CEBPZ	62	79.175	ENSCHOG00000013012	-	61	79.175	Choloepus_hoffmanni
ENSG00000115816	CEBPZ	97	68.169	ENSCPBG00000023684	CEBPZ	97	68.648	Chrysemys_picta_bellii
ENSG00000115816	CEBPZ	58	37.049	ENSCING00000021688	-	98	37.049	Ciona_intestinalis
ENSG00000115816	CEBPZ	100	96.584	ENSCANG00000033300	CEBPZ	100	96.584	Colobus_angolensis_palliatus
ENSG00000115816	CEBPZ	100	81.244	ENSCGRG00001024288	Cebpz	100	80.867	Cricetulus_griseus_chok1gshd
ENSG00000115816	CEBPZ	100	81.244	ENSCGRG00000014269	Cebpz	100	80.867	Cricetulus_griseus_crigri
ENSG00000115816	CEBPZ	99	52.881	ENSCSEG00000005661	cebpz	91	55.888	Cynoglossus_semilaevis
ENSG00000115816	CEBPZ	84	57.368	ENSCVAG00000018541	cebpz	93	59.274	Cyprinodon_variegatus
ENSG00000115816	CEBPZ	98	55.832	ENSDARG00000045857	cebpz	93	57.371	Danio_rerio
ENSG00000115816	CEBPZ	100	86.239	ENSDNOG00000002209	CEBPZ	100	86.239	Dasypus_novemcinctus
ENSG00000115816	CEBPZ	99	83.145	ENSDORG00000027348	Cebpz	97	83.687	Dipodomys_ordii
ENSG00000115816	CEBPZ	95	79.683	ENSETEG00000002400	CEBPZ	100	79.187	Echinops_telfairi
ENSG00000115816	CEBPZ	93	47.018	ENSEBUG00000015764	cebpz	93	48.387	Eptatretus_burgeri
ENSG00000115816	CEBPZ	100	87.112	ENSEASG00005007345	CEBPZ	100	87.112	Equus_asinus_asinus
ENSG00000115816	CEBPZ	100	87.300	ENSECAG00000018957	CEBPZ	100	87.300	Equus_caballus
ENSG00000115816	CEBPZ	97	69.863	ENSEEUG00000013490	CEBPZ	89	77.507	Erinaceus_europaeus
ENSG00000115816	CEBPZ	96	57.364	ENSELUG00000015123	cebpz	94	57.620	Esox_lucius
ENSG00000115816	CEBPZ	99	84.703	ENSFCAG00000015764	CEBPZ	99	85.364	Felis_catus
ENSG00000115816	CEBPZ	97	64.767	ENSFALG00000011758	CEBPZ	97	66.341	Ficedula_albicollis
ENSG00000115816	CEBPZ	100	84.087	ENSFDAG00000002926	CEBPZ	100	83.427	Fukomys_damarensis
ENSG00000115816	CEBPZ	83	55.231	ENSFHEG00000012867	cebpz	97	53.702	Fundulus_heteroclitus
ENSG00000115816	CEBPZ	93	54.374	ENSGMOG00000017880	cebpz	97	55.634	Gadus_morhua
ENSG00000115816	CEBPZ	83	68.367	ENSGALG00000040335	CEBPZ	94	64.902	Gallus_gallus
ENSG00000115816	CEBPZ	96	52.166	ENSGAFG00000014306	cebpz	93	54.264	Gambusia_affinis
ENSG00000115816	CEBPZ	94	57.086	ENSGACG00000011855	cebpz	97	57.762	Gasterosteus_aculeatus
ENSG00000115816	CEBPZ	98	67.173	ENSGAGG00000024100	CEBPZ	97	68.142	Gopherus_agassizii
ENSG00000115816	CEBPZ	100	99.241	ENSGGOG00000011349	CEBPZ	100	99.241	Gorilla_gorilla
ENSG00000115816	CEBPZ	95	57.143	ENSHBUG00000004917	cebpz	93	58.772	Haplochromis_burtoni
ENSG00000115816	CEBPZ	100	83.051	ENSHGLG00000012838	CEBPZ	100	82.486	Heterocephalus_glaber_female
ENSG00000115816	CEBPZ	100	84.463	ENSHGLG00100005398	CEBPZ	100	83.898	Heterocephalus_glaber_male
ENSG00000115816	CEBPZ	98	49.477	ENSHCOG00000012132	cebpz	92	50.510	Hippocampus_comes
ENSG00000115816	CEBPZ	97	56.978	ENSIPUG00000006584	cebpz	93	58.300	Ictalurus_punctatus
ENSG00000115816	CEBPZ	100	87.194	ENSSTOG00000026177	CEBPZ	100	87.194	Ictidomys_tridecemlineatus
ENSG00000115816	CEBPZ	100	84.652	ENSJJAG00000011428	Cebpz	100	84.652	Jaculus_jaculus
ENSG00000115816	CEBPZ	96	52.236	ENSKMAG00000001280	cebpz	95	53.854	Kryptolebias_marmoratus
ENSG00000115816	CEBPZ	84	59.489	ENSLBEG00000023442	CEBPZ	93	60.509	Labrus_bergylta
ENSG00000115816	CEBPZ	93	62.805	ENSLACG00000012928	CEBPZ	96	63.110	Latimeria_chalumnae
ENSG00000115816	CEBPZ	97	60.762	ENSLOCG00000016867	cebpz	93	62.266	Lepisosteus_oculatus
ENSG00000115816	CEBPZ	100	87.665	ENSLAFG00000000953	CEBPZ	100	87.665	Loxodonta_africana
ENSG00000115816	CEBPZ	100	96.015	ENSMFAG00000042567	CEBPZ	100	95.541	Macaca_fascicularis
ENSG00000115816	CEBPZ	100	95.920	ENSMMUG00000016433	CEBPZ	100	95.446	Macaca_mulatta
ENSG00000115816	CEBPZ	100	95.731	ENSMNEG00000039414	CEBPZ	100	95.256	Macaca_nemestrina
ENSG00000115816	CEBPZ	98	96.318	ENSMLEG00000031611	CEBPZ	100	96.300	Mandrillus_leucophaeus
ENSG00000115816	CEBPZ	97	55.764	ENSMAMG00000019826	cebpz	91	56.936	Mastacembelus_armatus
ENSG00000115816	CEBPZ	93	57.367	ENSMZEG00005013159	cebpz	93	58.074	Maylandia_zebra
ENSG00000115816	CEBPZ	83	67.571	ENSMGAG00000011280	CEBPZ	94	64.244	Meleagris_gallopavo
ENSG00000115816	CEBPZ	100	80.548	ENSMAUG00000008610	Cebpz	100	80.170	Mesocricetus_auratus
ENSG00000115816	CEBPZ	100	88.113	ENSMICG00000003324	CEBPZ	100	88.941	Microcebus_murinus
ENSG00000115816	CEBPZ	100	80.961	ENSMOCG00000018640	Cebpz	100	80.584	Microtus_ochrogaster
ENSG00000115816	CEBPZ	97	52.510	ENSMMOG00000017553	cebpz	91	54.636	Mola_mola
ENSG00000115816	CEBPZ	100	72.600	ENSMODG00000023074	CEBPZ	97	72.658	Monodelphis_domestica
ENSG00000115816	CEBPZ	97	53.448	ENSMALG00000010892	cebpz	89	61.849	Monopterus_albus
ENSG00000115816	CEBPZ	97	69.655	MGP_CAROLIEiJ_G0021891	-	77	83.187	Mus_caroli
ENSG00000115816	CEBPZ	100	81.338	ENSMUSG00000024081	Cebpz	100	80.961	Mus_musculus
ENSG00000115816	CEBPZ	100	81.904	MGP_SPRETEiJ_G0022806	Cebpz	100	81.527	Mus_spretus
ENSG00000115816	CEBPZ	100	87.747	ENSMPUG00000010216	CEBPZ	96	87.747	Mustela_putorius_furo
ENSG00000115816	CEBPZ	100	85.768	ENSMLUG00000008929	CEBPZ	100	85.957	Myotis_lucifugus
ENSG00000115816	CEBPZ	100	84.290	ENSNGAG00000015241	Cebpz	100	82.879	Nannospalax_galili
ENSG00000115816	CEBPZ	87	60.000	ENSNBRG00000008466	cebpz	95	53.974	Neolamprologus_brichardi
ENSG00000115816	CEBPZ	100	97.818	ENSNLEG00000016237	CEBPZ	100	97.818	Nomascus_leucogenys
ENSG00000115816	CEBPZ	83	81.215	ENSMEUG00000011839	-	84	81.215	Notamacropus_eugenii
ENSG00000115816	CEBPZ	90	77.341	ENSOPRG00000008189	CEBPZ	92	77.341	Ochotona_princeps
ENSG00000115816	CEBPZ	58	83.764	ENSODEG00000011002	-	99	83.764	Octodon_degus
ENSG00000115816	CEBPZ	95	57.310	ENSONIG00000018713	cebpz	93	58.946	Oreochromis_niloticus
ENSG00000115816	CEBPZ	99	67.202	ENSOANG00000005120	CEBPZ	98	68.380	Ornithorhynchus_anatinus
ENSG00000115816	CEBPZ	100	86.441	ENSOCUG00000007230	CEBPZ	100	86.441	Oryctolagus_cuniculus
ENSG00000115816	CEBPZ	98	55.251	ENSORLG00000017177	cebpz	93	57.101	Oryzias_latipes
ENSG00000115816	CEBPZ	98	55.345	ENSORLG00020001900	cebpz	94	56.811	Oryzias_latipes_hni
ENSG00000115816	CEBPZ	98	55.198	ENSORLG00015019923	cebpz	93	57.129	Oryzias_latipes_hsok
ENSG00000115816	CEBPZ	99	55.432	ENSOMEG00000019691	cebpz	93	57.988	Oryzias_melastigma
ENSG00000115816	CEBPZ	100	88.258	ENSOGAG00000002565	CEBPZ	100	88.258	Otolemur_garnettii
ENSG00000115816	CEBPZ	100	84.102	ENSOARG00000009540	CEBPZ	99	84.008	Ovis_aries
ENSG00000115816	CEBPZ	100	98.672	ENSPPAG00000043370	CEBPZ	100	98.672	Pan_paniscus
ENSG00000115816	CEBPZ	99	86.282	ENSPPRG00000003326	CEBPZ	99	86.944	Panthera_pardus
ENSG00000115816	CEBPZ	99	86.566	ENSPTIG00000014858	CEBPZ	99	87.228	Panthera_tigris_altaica
ENSG00000115816	CEBPZ	100	98.767	ENSPTRG00000011836	CEBPZ	100	98.767	Pan_troglodytes
ENSG00000115816	CEBPZ	100	96.300	ENSPANG00000015853	CEBPZ	100	96.300	Papio_anubis
ENSG00000115816	CEBPZ	98	58.168	ENSPKIG00000023192	cebpz	93	59.369	Paramormyrops_kingsleyae
ENSG00000115816	CEBPZ	99	67.901	ENSPSIG00000006455	CEBPZ	96	68.812	Pelodiscus_sinensis
ENSG00000115816	CEBPZ	84	54.167	ENSPMGG00000017825	cebpz	92	50.442	Periophthalmus_magnuspinnatus
ENSG00000115816	CEBPZ	100	81.810	ENSPEMG00000017978	Cebpz	98	82.319	Peromyscus_maniculatus_bairdii
ENSG00000115816	CEBPZ	100	71.508	ENSPCIG00000007283	CEBPZ	98	72.901	Phascolarctos_cinereus
ENSG00000115816	CEBPZ	96	53.372	ENSPFOG00000003831	cebpz	95	55.413	Poecilia_formosa
ENSG00000115816	CEBPZ	96	53.455	ENSPLAG00000016264	cebpz	95	55.336	Poecilia_latipinna
ENSG00000115816	CEBPZ	96	53.616	ENSPMEG00000013419	cebpz	95	55.206	Poecilia_mexicana
ENSG00000115816	CEBPZ	89	54.040	ENSPREG00000012387	cebpz	94	55.021	Poecilia_reticulata
ENSG00000115816	CEBPZ	100	98.008	ENSPPYG00000012491	CEBPZ	100	98.008	Pongo_abelii
ENSG00000115816	CEBPZ	91	82.830	ENSPCAG00000012718	CEBPZ	100	82.830	Procavia_capensis
ENSG00000115816	CEBPZ	100	89.130	ENSPCOG00000017899	CEBPZ	100	89.130	Propithecus_coquereli
ENSG00000115816	CEBPZ	87	83.963	ENSPVAG00000013834	CEBPZ	87	83.276	Pteropus_vampyrus
ENSG00000115816	CEBPZ	95	54.341	ENSPNYG00000001483	cebpz	92	55.268	Pundamilia_nyererei
ENSG00000115816	CEBPZ	98	55.379	ENSPNAG00000010829	cebpz	94	58.117	Pygocentrus_nattereri
ENSG00000115816	CEBPZ	100	81.209	ENSRNOG00000005087	Cebpz	100	80.642	Rattus_norvegicus
ENSG00000115816	CEBPZ	99	95.091	ENSRBIG00000035805	CEBPZ	99	95.428	Rhinopithecus_bieti
ENSG00000115816	CEBPZ	100	96.300	ENSRROG00000045300	CEBPZ	100	96.300	Rhinopithecus_roxellana
ENSG00000115816	CEBPZ	100	94.787	ENSSBOG00000032043	CEBPZ	100	94.787	Saimiri_boliviensis_boliviensis
ENSG00000115816	CEBPZ	100	72.346	ENSSHAG00000010396	CEBPZ	92	72.901	Sarcophilus_harrisii
ENSG00000115816	CEBPZ	96	59.309	ENSSFOG00015001353	cebpz	93	59.824	Scleropages_formosus
ENSG00000115816	CEBPZ	97	56.437	ENSSMAG00000007770	cebpz	92	57.640	Scophthalmus_maximus
ENSG00000115816	CEBPZ	97	56.226	ENSSDUG00000013019	cebpz	92	57.977	Seriola_dumerili
ENSG00000115816	CEBPZ	97	55.753	ENSSLDG00000021173	cebpz	92	58.068	Seriola_lalandi_dorsalis
ENSG00000115816	CEBPZ	97	66.986	ENSSPUG00000017394	CEBPZ	95	68.379	Sphenodon_punctatus
ENSG00000115816	CEBPZ	97	39.456	ENSSPAG00000022987	CEBPZ	89	53.089	Stegastes_partitus
ENSG00000115816	CEBPZ	100	83.097	ENSSSCG00000008493	CEBPZ	100	85.014	Sus_scrofa
ENSG00000115816	CEBPZ	96	64.513	ENSTGUG00000008585	CEBPZ	97	65.769	Taeniopygia_guttata
ENSG00000115816	CEBPZ	94	55.030	ENSTRUG00000015584	CEBPZ	94	56.754	Takifugu_rubripes
ENSG00000115816	CEBPZ	98	85.659	ENSTBEG00000012108	CEBPZ	100	85.566	Tupaia_belangeri
ENSG00000115816	CEBPZ	100	85.499	ENSTTRG00000006886	CEBPZ	100	85.782	Tursiops_truncatus
ENSG00000115816	CEBPZ	99	80.405	ENSUAMG00000006489	CEBPZ	99	85.744	Ursus_americanus
ENSG00000115816	CEBPZ	100	87.653	ENSUMAG00000014757	CEBPZ	100	87.653	Ursus_maritimus
ENSG00000115816	CEBPZ	100	85.513	ENSVPAG00000003306	CEBPZ	100	85.325	Vicugna_pacos
ENSG00000115816	CEBPZ	96	86.444	ENSVVUG00000018894	CEBPZ	95	86.837	Vulpes_vulpes
ENSG00000115816	CEBPZ	96	58.577	ENSXETG00000000654	cebpz	96	58.911	Xenopus_tropicalis
ENSG00000115816	CEBPZ	96	34.752	ENSXCOG00000000898	cebpz	94	70.000	Xiphophorus_couchianus
ENSG00000115816	CEBPZ	93	52.448	ENSXMAG00000007499	cebpz	97	54.974	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding	2247079.	IDA	Function
GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	19274049.	ISM	Function
GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	19274049.	NAS	Function
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	2247079.	IDA	Function
GO:0003677	DNA binding	2247079.	TAS	Function
GO:0003723	RNA binding	22658674.22681889.	HDA	Function
GO:0005634	nucleus	21873635.	IBA	Component
GO:0006366	transcription by RNA polymerase II	2247079.	TAS	Process
GO:0042254	ribosome biogenesis	-	IEA	Process
GO:0045944	positive regulation of transcription by RNA polymerase II	2247079.	IDA	Process