EuRBPDB

Description

RBDs

RBPome

Literatures

Expression

Transcripts

Gene Model

Pathways

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000116698 (Gene tree)
Gene ID: 9887
Gene Symbol: SMG7
Alias: KIAA0250|EST1C|SGA56M|SMG-7|C1orf16
Full Name: SMG7 nonsense mediated mRNA decay factor
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Plus strand
Length: 126,031 bases
Position: chr1:183,472,216-183,598,246
Accession: 16792
RBP type: canonical RBP
Summary: This gene encodes a protein that is essential for nonsense-mediated mRNA decay (NMD); a process whereby transcripts with premature termination codons are targeted for rapid degradation by a mRNA decay complex. The mRNA decay complex consists, in part, of this protein along with proteins SMG5 and UPF1. The N-terminal domain of this protein is thought to mediate its association with SMG5 or UPF1 while the C-terminal domain interacts with the mRNA decay complex. This protein may therefore couple changes in UPF1 phosphorylation state to the degradation of NMD-candidate transcripts. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Aug 2011]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000388390	EST1	PF10374.9	1.3e-24	1	1
ENSP00000421358	EST1	PF10374.9	2.6e-24	1	1
ENSP00000340766	EST1	PF10374.9	2.6e-24	1	1
ENSP00000426915	EST1	PF10374.9	2.7e-24	1	1
ENSP00000356507	EST1	PF10374.9	2.8e-24	1	1
ENSP00000425133	EST1	PF10374.9	2.8e-24	1	1
ENSP00000422742	EST1	PF10374.9	5e-13	1	1
ENSP00000388390	EST1_DNA_bind	PF10373.9	4.8e-55	1	1
ENSP00000421358	EST1_DNA_bind	PF10373.9	9.6e-55	1	1
ENSP00000340766	EST1_DNA_bind	PF10373.9	1e-54	1	1
ENSP00000426915	EST1_DNA_bind	PF10373.9	1e-54	1	1
ENSP00000356507	EST1_DNA_bind	PF10373.9	1.1e-54	1	1
ENSP00000425133	EST1_DNA_bind	PF10373.9	1.1e-54	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
29431736	Capturing the interactome of newly transcribed RNA	RIC & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
25184677	A post-translational regulatory switch on UPF1 controls targeted mRNA degradation.	Genes Dev	2014 Sep 1	Kurosaki T	doi: 10.1101/gad.245506.114.

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000444547	SMG7-206	580	-	ENSP00000400220	73 (aa)	-	E9PBK2
ENST00000367537	SMG7-202	5970	XM_005245649	ENSP00000356507	1170 (aa)	XP_005245706	E9PD50
ENST00000495321	SMG7-209	556	-	-	- (aa)	-	-
ENST00000638826	SMG7-216	219	-	ENSP00000492670	73 (aa)	-	E9PBK2
ENST00000419169	SMG7-204	2483	-	ENSP00000388390	756 (aa)	-	B1ALB4
ENST00000493609	SMG7-208	624	-	-	- (aa)	-	-
ENST00000508461	SMG7-214	3985	XM_005245653	ENSP00000426915	1145 (aa)	XP_005245710	Q92540
ENST00000507469	SMG7-212	4642	-	ENSP00000425133	1178 (aa)	-	Q92540
ENST00000493045	SMG7-207	673	-	-	- (aa)	-	-
ENST00000367538	SMG7-203	328	-	-	- (aa)	-	-
ENST00000507406	SMG7-211	582	-	-	- (aa)	-	-
ENST00000440812	SMG7-205	1190	-	ENSP00000410254	184 (aa)	-	E9PEK3
ENST00000502375	SMG7-210	566	-	ENSP00000422056	56 (aa)	-	D6R9J3
ENST00000515829	SMG7-215	5629	XM_006711678	ENSP00000421358	1091 (aa)	XP_006711741	Q92540
ENST00000347615	SMG7-201	5788	XM_005245652	ENSP00000340766	1137 (aa)	XP_005245709	Q92540
ENST00000507691	SMG7-213	760	-	ENSP00000422742	150 (aa)	-	D6RAD0

Gene Model

Click here to download ENSG00000116698's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa03015	mRNA surveillance pathway	KEGG

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000116698	Platelet Function Tests	2.2204460E-016	-
ENSG00000116698	Child Development Disorders, Pervasive	1.4328000E-005	-
ENSG00000116698	Child Development Disorders, Pervasive	3.0323000E-005	-
ENSG00000116698	Child Development Disorders, Pervasive	5.0131000E-005	-
ENSG00000116698	Child Development Disorders, Pervasive	2.5521000E-005	-

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000116698	rs17849502	1	183563445	T	Systemic lupus erythematosus	28714469	[1.59-2.38]	1.95	EFO_0002690
ENSG00000116698	rs17849501	1	183573188	?	Systemic lupus erythematosus	27399966	[NR]	2.24	EFO_0002690
ENSG00000116698	rs17849501	1	183573188	T	Systemic lupus erythematosus	26502338	[NR]	2.01	EFO_0002690
ENSG00000116698	rs13306575	1	183563302	A	Systemic lupus erythematosus	26606652	[1.39-1.91]	1.62	EFO_0002690
ENSG00000116698	rs2794619	1	183490535	?	General cognitive ability	29844566	z-score increase	5.396	EFO_0004337
ENSG00000116698	rs789182	1	183557968	?	Reaction time	29844566	[0.0053-0.0122] unit increase	0.0087639	EFO_0008393
ENSG00000116698	rs17849502	1	183563445	T	Systemic seropositive rheumatic diseases (Systemic sclerosis or systemic lupus erythematosus or rheumatoid arthritis or idiopathic inflammatory myopathies)	30573655	[1.16-1.59]	1.36	EFO_0000717\|EFO_0000685\|EFO_0000783\|EFO_0002690

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000116698's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000116698	SMG7	85	92.994	ENSAPOG00000009611	smg7	95	74.433	Acanthochromis_polyacanthus
ENSG00000116698	SMG7	100	96.856	ENSAMEG00000002357	SMG7	100	96.856	Ailuropoda_melanoleuca
ENSG00000116698	SMG7	70	94.574	ENSACIG00000015152	smg7	100	64.884	Amphilophus_citrinellus
ENSG00000116698	SMG7	86	94.340	ENSAOCG00000013538	smg7	99	66.838	Amphiprion_ocellaris
ENSG00000116698	SMG7	86	94.340	ENSAPEG00000007851	smg7	99	66.695	Amphiprion_percula
ENSG00000116698	SMG7	86	94.340	ENSATEG00000006931	smg7	99	66.299	Anabas_testudineus
ENSG00000116698	SMG7	100	88.976	ENSAPLG00000015811	SMG7	100	88.801	Anas_platyrhynchos
ENSG00000116698	SMG7	100	87.532	ENSACAG00000014989	SMG7	96	88.052	Anolis_carolinensis
ENSG00000116698	SMG7	100	100.000	ENSANAG00000028114	SMG7	100	98.593	Aotus_nancymaae
ENSG00000116698	SMG7	86	94.340	ENSACLG00000022079	smg7	99	66.324	Astatotilapia_calliptera
ENSG00000116698	SMG7	86	93.711	ENSAMXG00000020809	smg7	99	68.028	Astyanax_mexicanus
ENSG00000116698	SMG7	100	99.333	ENSBTAG00000008003	SMG7	100	96.410	Bos_taurus
ENSG00000116698	SMG7	99	100.000	ENSCJAG00000005135	SMG7	100	98.370	Callithrix_jacchus
ENSG00000116698	SMG7	100	98.667	ENSCAFG00000013276	SMG7	100	97.265	Canis_familiaris
ENSG00000116698	SMG7	100	98.667	ENSCAFG00020015475	SMG7	100	97.265	Canis_lupus_dingo
ENSG00000116698	SMG7	100	96.561	ENSCHIG00000018192	SMG7	99	96.381	Capra_hircus
ENSG00000116698	SMG7	100	98.667	ENSTSYG00000002667	SMG7	100	97.449	Carlito_syrichta
ENSG00000116698	SMG7	100	97.619	ENSCPOG00000008906	SMG7	100	97.599	Cavia_porcellus
ENSG00000116698	SMG7	100	98.690	ENSCCAG00000028596	SMG7	100	98.690	Cebus_capucinus
ENSG00000116698	SMG7	100	100.000	ENSCATG00000011063	SMG7	100	99.487	Cercocebus_atys
ENSG00000116698	SMG7	100	100.000	ENSCLAG00000010751	SMG7	100	97.265	Chinchilla_lanigera
ENSG00000116698	SMG7	100	100.000	ENSCSAG00000012654	SMG7	100	99.316	Chlorocebus_sabaeus
ENSG00000116698	SMG7	96	93.827	ENSCHOG00000010522	SMG7	99	88.541	Choloepus_hoffmanni
ENSG00000116698	SMG7	100	91.906	ENSCPBG00000015724	SMG7	100	91.499	Chrysemys_picta_bellii
ENSG00000116698	SMG7	85	52.147	ENSCING00000006953	-	94	53.746	Ciona_intestinalis
ENSG00000116698	SMG7	100	99.389	ENSCANG00000015680	SMG7	100	99.389	Colobus_angolensis_palliatus
ENSG00000116698	SMG7	100	96.429	ENSCGRG00001013705	Smg7	100	96.141	Cricetulus_griseus_chok1gshd
ENSG00000116698	SMG7	100	96.429	ENSCGRG00000018401	Smg7	100	96.084	Cricetulus_griseus_crigri
ENSG00000116698	SMG7	83	90.789	ENSCSEG00000007392	-	88	89.103	Cynoglossus_semilaevis
ENSG00000116698	SMG7	79	89.189	ENSCVAG00000011842	smg7	99	69.500	Cyprinodon_variegatus
ENSG00000116698	SMG7	86	94.969	ENSDARG00000060767	smg7	99	67.761	Danio_rerio
ENSG00000116698	SMG7	100	96.958	ENSDORG00000007331	Smg7	100	96.606	Dipodomys_ordii
ENSG00000116698	SMG7	100	97.222	ENSETEG00000002654	SMG7	100	96.286	Echinops_telfairi
ENSG00000116698	SMG7	100	99.333	ENSEASG00005006524	SMG7	100	97.778	Equus_asinus_asinus
ENSG00000116698	SMG7	100	99.333	ENSECAG00000004313	SMG7	100	97.863	Equus_caballus
ENSG00000116698	SMG7	100	96.693	ENSEEUG00000002024	SMG7	99	93.793	Erinaceus_europaeus
ENSG00000116698	SMG7	86	94.340	ENSELUG00000010293	smg7	99	66.515	Esox_lucius
ENSG00000116698	SMG7	99	99.329	ENSFCAG00000010900	SMG7	100	97.519	Felis_catus
ENSG00000116698	SMG7	100	86.111	ENSFALG00000003047	SMG7	98	86.024	Ficedula_albicollis
ENSG00000116698	SMG7	100	97.354	ENSFDAG00000012121	SMG7	99	97.148	Fukomys_damarensis
ENSG00000116698	SMG7	88	90.062	ENSFHEG00000011073	smg7	99	63.884	Fundulus_heteroclitus
ENSG00000116698	SMG7	88	90.683	ENSGMOG00000004916	smg7	92	67.883	Gadus_morhua
ENSG00000116698	SMG7	100	89.336	ENSGALG00000004667	SMG7	100	89.161	Gallus_gallus
ENSG00000116698	SMG7	94	85.876	ENSGAFG00000019000	smg7	99	64.397	Gambusia_affinis
ENSG00000116698	SMG7	88	91.925	ENSGACG00000001634	smg7	99	65.061	Gasterosteus_aculeatus
ENSG00000116698	SMG7	95	89.655	ENSGAGG00000024208	-	86	95.062	Gopherus_agassizii
ENSG00000116698	SMG7	100	99.603	ENSGGOG00000002342	SMG7	100	99.563	Gorilla_gorilla
ENSG00000116698	SMG7	86	94.340	ENSHBUG00000003726	smg7	97	72.589	Haplochromis_burtoni
ENSG00000116698	SMG7	100	97.354	ENSHGLG00000009353	SMG7	100	97.237	Heterocephalus_glaber_female
ENSG00000116698	SMG7	100	89.947	ENSHGLG00100004878	-	99	89.144	Heterocephalus_glaber_male
ENSG00000116698	SMG7	100	97.274	ENSHGLG00100009637	-	100	97.274	Heterocephalus_glaber_male
ENSG00000116698	SMG7	95	78.977	ENSHCOG00000012804	-	88	84.242	Hippocampus_comes
ENSG00000116698	SMG7	86	93.711	ENSIPUG00000016997	smg7	99	68.499	Ictalurus_punctatus
ENSG00000116698	SMG7	100	97.892	ENSSTOG00000000401	SMG7	100	97.998	Ictidomys_tridecemlineatus
ENSG00000116698	SMG7	100	96.561	ENSJJAG00000012351	Smg7	99	95.499	Jaculus_jaculus
ENSG00000116698	SMG7	95	86.782	ENSJJAG00000000309	-	98	86.782	Jaculus_jaculus
ENSG00000116698	SMG7	72	93.182	ENSKMAG00000004900	smg7	97	70.500	Kryptolebias_marmoratus
ENSG00000116698	SMG7	73	64.273	ENSLBEG00000005220	-	75	64.273	Labrus_bergylta
ENSG00000116698	SMG7	84	92.903	ENSLBEG00000002983	smg7	99	66.350	Labrus_bergylta
ENSG00000116698	SMG7	86	94.969	ENSLACG00000000972	SMG7	99	75.760	Latimeria_chalumnae
ENSG00000116698	SMG7	88	92.683	ENSLOCG00000002010	smg7	99	67.809	Lepisosteus_oculatus
ENSG00000116698	SMG7	100	97.619	ENSLAFG00000008186	SMG7	100	97.389	Loxodonta_africana
ENSG00000116698	SMG7	100	100.000	ENSMFAG00000031653	SMG7	100	99.402	Macaca_fascicularis
ENSG00000116698	SMG7	100	100.000	ENSMMUG00000018458	SMG7	100	99.487	Macaca_mulatta
ENSG00000116698	SMG7	100	99.476	ENSMNEG00000034798	SMG7	100	99.476	Macaca_nemestrina
ENSG00000116698	SMG7	100	100.000	ENSMLEG00000037170	SMG7	100	99.487	Mandrillus_leucophaeus
ENSG00000116698	SMG7	88	92.547	ENSMAMG00000018733	smg7	85	65.377	Mastacembelus_armatus
ENSG00000116698	SMG7	86	94.340	ENSMZEG00005015247	smg7	99	65.897	Maylandia_zebra
ENSG00000116698	SMG7	97	89.218	ENSMGAG00000001561	SMG7	98	89.039	Meleagris_gallopavo
ENSG00000116698	SMG7	100	96.958	ENSMAUG00000019484	Smg7	100	96.519	Mesocricetus_auratus
ENSG00000116698	SMG7	100	98.417	ENSMICG00000007145	SMG7	100	98.417	Microcebus_murinus
ENSG00000116698	SMG7	100	96.561	ENSMOCG00000020748	Smg7	100	96.345	Microtus_ochrogaster
ENSG00000116698	SMG7	85	90.446	ENSMMOG00000001524	smg7	99	64.416	Mola_mola
ENSG00000116698	SMG7	100	89.651	ENSMODG00000007139	SMG7	99	93.169	Monodelphis_domestica
ENSG00000116698	SMG7	87	93.125	ENSMALG00000000061	smg7	95	68.657	Monopterus_albus
ENSG00000116698	SMG7	100	96.032	MGP_CAROLIEiJ_G0014704	Smg7	100	95.735	Mus_caroli
ENSG00000116698	SMG7	100	95.899	ENSMUSG00000042772	Smg7	100	95.997	Mus_musculus
ENSG00000116698	SMG7	100	96.429	MGP_PahariEiJ_G0027940	Smg7	100	96.084	Mus_pahari
ENSG00000116698	SMG7	100	96.032	MGP_SPRETEiJ_G0015511	Smg7	100	96.084	Mus_spretus
ENSG00000116698	SMG7	100	97.354	ENSMPUG00000011732	SMG7	97	97.237	Mustela_putorius_furo
ENSG00000116698	SMG7	100	97.222	ENSMLUG00000015417	SMG7	99	96.734	Myotis_lucifugus
ENSG00000116698	SMG7	100	97.354	ENSNGAG00000009836	Smg7	100	96.519	Nannospalax_galili
ENSG00000116698	SMG7	98	61.304	ENSNBRG00000024343	smg7	98	70.476	Neolamprologus_brichardi
ENSG00000116698	SMG7	100	100.000	ENSNLEG00000018018	SMG7	100	99.658	Nomascus_leucogenys
ENSG00000116698	SMG7	87	85.687	ENSMEUG00000004681	SMG7	82	86.750	Notamacropus_eugenii
ENSG00000116698	SMG7	99	87.268	ENSOPRG00000013942	SMG7	96	84.475	Ochotona_princeps
ENSG00000116698	SMG7	100	98.148	ENSODEG00000010390	SMG7	100	97.302	Octodon_degus
ENSG00000116698	SMG7	86	94.340	ENSONIG00000000277	smg7	99	65.925	Oreochromis_niloticus
ENSG00000116698	SMG7	100	91.041	ENSOANG00000000994	SMG7	100	90.957	Ornithorhynchus_anatinus
ENSG00000116698	SMG7	100	95.333	ENSOCUG00000005887	SMG7	95	89.915	Oryctolagus_cuniculus
ENSG00000116698	SMG7	93	85.965	ENSORLG00000007314	smg7	77	85.965	Oryzias_latipes
ENSG00000116698	SMG7	88	90.683	ENSORLG00020015779	smg7	78	85.057	Oryzias_latipes_hni
ENSG00000116698	SMG7	88	90.683	ENSORLG00015012289	smg7	99	63.629	Oryzias_latipes_hsok
ENSG00000116698	SMG7	88	90.683	ENSOMEG00000002328	smg7	99	62.438	Oryzias_melastigma
ENSG00000116698	SMG7	100	98.016	ENSOGAG00000003107	SMG7	100	94.732	Otolemur_garnettii
ENSG00000116698	SMG7	100	99.333	ENSOARG00000001352	SMG7	100	96.239	Ovis_aries
ENSG00000116698	SMG7	100	99.825	ENSPPAG00000031619	SMG7	100	99.825	Pan_paniscus
ENSG00000116698	SMG7	99	99.329	ENSPPRG00000011222	SMG7	100	97.801	Panthera_pardus
ENSG00000116698	SMG7	100	97.884	ENSPTIG00000007242	SMG7	100	97.729	Panthera_tigris_altaica
ENSG00000116698	SMG7	100	99.825	ENSPTRG00000001764	SMG7	100	99.825	Pan_troglodytes
ENSG00000116698	SMG7	100	100.000	ENSPANG00000004520	SMG7	100	99.487	Papio_anubis
ENSG00000116698	SMG7	86	92.405	ENSPKIG00000007242	smg7	99	68.500	Paramormyrops_kingsleyae
ENSG00000116698	SMG7	100	91.667	ENSPSIG00000012201	SMG7	99	91.557	Pelodiscus_sinensis
ENSG00000116698	SMG7	85	85.987	ENSPMGG00000002179	-	93	81.065	Periophthalmus_magnuspinnatus
ENSG00000116698	SMG7	59	57.000	ENSPMGG00000021833	smg7	79	70.796	Periophthalmus_magnuspinnatus
ENSG00000116698	SMG7	100	95.238	ENSPEMG00000011315	Smg7	100	95.213	Peromyscus_maniculatus_bairdii
ENSG00000116698	SMG7	100	93.630	ENSPCIG00000003786	SMG7	100	93.409	Phascolarctos_cinereus
ENSG00000116698	SMG7	86	91.824	ENSPFOG00000019219	smg7	99	62.862	Poecilia_formosa
ENSG00000116698	SMG7	86	91.824	ENSPLAG00000001446	smg7	99	64.513	Poecilia_latipinna
ENSG00000116698	SMG7	88	90.683	ENSPMEG00000005218	smg7	99	63.790	Poecilia_mexicana
ENSG00000116698	SMG7	88	90.062	ENSPREG00000019039	smg7	91	61.759	Poecilia_reticulata
ENSG00000116698	SMG7	100	99.736	ENSPPYG00000000427	SMG7	100	99.736	Pongo_abelii
ENSG00000116698	SMG7	98	84.024	ENSPCAG00000008360	SMG7	100	84.024	Procavia_capensis
ENSG00000116698	SMG7	100	98.667	ENSPCOG00000011996	SMG7	100	98.350	Propithecus_coquereli
ENSG00000116698	SMG7	100	90.621	ENSPVAG00000000851	SMG7	100	85.544	Pteropus_vampyrus
ENSG00000116698	SMG7	86	94.340	ENSPNYG00000007643	smg7	99	66.179	Pundamilia_nyererei
ENSG00000116698	SMG7	86	94.340	ENSPNAG00000011374	smg7	98	69.697	Pygocentrus_nattereri
ENSG00000116698	SMG7	100	96.296	ENSRNOG00000027962	Smg7	100	96.296	Rattus_norvegicus
ENSG00000116698	SMG7	100	100.000	ENSRBIG00000036316	SMG7	100	99.402	Rhinopithecus_bieti
ENSG00000116698	SMG7	100	100.000	ENSRROG00000035719	SMG7	100	99.402	Rhinopithecus_roxellana
ENSG00000116698	SMG7	100	99.457	ENSSBOG00000023454	SMG7	100	99.457	Saimiri_boliviensis_boliviensis
ENSG00000116698	SMG7	100	92.976	ENSSHAG00000013147	SMG7	100	92.713	Sarcophilus_harrisii
ENSG00000116698	SMG7	86	93.082	ENSSFOG00015017252	smg7	99	76.842	Scleropages_formosus
ENSG00000116698	SMG7	88	93.168	ENSSMAG00000006067	smg7	99	65.978	Scophthalmus_maximus
ENSG00000116698	SMG7	86	94.340	ENSSDUG00000017543	smg7	99	65.850	Seriola_dumerili
ENSG00000116698	SMG7	88	93.210	ENSSLDG00000003750	-	97	93.210	Seriola_lalandi_dorsalis
ENSG00000116698	SMG7	99	90.371	ENSSPUG00000002064	SMG7	99	90.194	Sphenodon_punctatus
ENSG00000116698	SMG7	89	85.366	ENSSPAG00000008733	smg7	100	65.891	Stegastes_partitus
ENSG00000116698	SMG7	100	98.148	ENSSSCG00000015558	SMG7	100	97.525	Sus_scrofa
ENSG00000116698	SMG7	99	89.251	ENSTGUG00000003928	SMG7	100	89.163	Taeniopygia_guttata
ENSG00000116698	SMG7	92	83.529	ENSTRUG00000003612	-	92	83.529	Takifugu_rubripes
ENSG00000116698	SMG7	86	89.375	ENSTNIG00000002802	smg7	99	63.697	Tetraodon_nigroviridis
ENSG00000116698	SMG7	78	96.610	ENSTBEG00000003220	SMG7	81	93.562	Tupaia_belangeri
ENSG00000116698	SMG7	100	97.751	ENSTTRG00000014778	SMG7	100	95.986	Tursiops_truncatus
ENSG00000116698	SMG7	100	97.487	ENSUAMG00000017473	SMG7	100	97.426	Ursus_americanus
ENSG00000116698	SMG7	100	97.487	ENSUMAG00000016389	SMG7	100	97.426	Ursus_maritimus
ENSG00000116698	SMG7	55	97.917	ENSVPAG00000005367	-	62	97.917	Vicugna_pacos
ENSG00000116698	SMG7	100	98.667	ENSVVUG00000008976	SMG7	100	97.434	Vulpes_vulpes
ENSG00000116698	SMG7	89	91.463	ENSXETG00000012528	smg7	100	70.859	Xenopus_tropicalis
ENSG00000116698	SMG7	86	92.453	ENSXMAG00000007123	smg7	99	64.464	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	16488880.	TAS	Process
GO:0005515	protein binding	14636577.20930030.23348841.	IPI	Function
GO:0005634	nucleus	14636577.	IDA	Component
GO:0005697	telomerase holoenzyme complex	21873635.	IBA	Component
GO:0005737	cytoplasm	21873635.	IBA	Component
GO:0005737	cytoplasm	14636577.	IDA	Component
GO:0005829	cytosol	-	IDA	Component
GO:0005829	cytosol	-	TAS	Component
GO:0006406	mRNA export from nucleus	16488880.	TAS	Process
GO:0007004	telomere maintenance via telomerase	21873635.	IBA	Process
GO:0032210	regulation of telomere maintenance via telomerase	21873635.	IBA	Process
GO:0035303	regulation of dephosphorylation	15721257.	TAS	Process
GO:0042162	telomeric DNA binding	21873635.	IBA	Function
GO:0042162	telomeric DNA binding	17916692.	IDA	Function
GO:0045111	intermediate filament cytoskeleton	-	IDA	Component
GO:0051721	protein phosphatase 2A binding	14636577.	IDA	Function
GO:0070034	telomerase RNA binding	21873635.	IBA	Function