EuRBPDB

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  • Description
  • RBPome
  • Expression
  • Transcripts
  • Gene Model
  • Phenotypes
  • GWAS
  • PPI
  • Orthologs
  • Gene Ontology
Description
Ensembl ID
ENSG00000117523 (Gene tree)
Gene ID
23215
Gene Symbol
PRRC2C
Alias
KIAA1096|XTP2|BAT2D1|BAT2L2
Full Name
proline rich coiled-coil 2C
Gene Type
protein_coding
Species
Homo_sapiens
Status
putative
Strand
Plus strand
Length
107,999 bases
Position
chr1:171,485,513-171,593,511
Accession
24903
RBP type
non-canonical RBP
Summary
(Proline Rich Coiled-Coil 2C) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include protein C-terminus binding. An important paralog of this gene is PRRC2B.
RNA binding proteome (RBPome)
PIDTitleMethod TimeAuthorDoi
22681889The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts4SURIC & HEK2932012 MayBaltz AGDOI: 10.1016/j.molcel.2012.05.021
30607034Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)OOPS & HEK2932019 Jan 3Queiroz RMLDOI: 10.1038/s41587-018-0001-2
30528433The Human RNA-Binding Proteome and Its Dynamics during Translational ArrestXRNAX & HEK2932018 Dec 6Trendel JDOI: 10.1016/j.cell.2018.11.004
29431736Capturing the interactome of newly transcribed RNAPolyT-RICK & Hela2018 Feb 12Bao XDOI: 10.1038/nmeth.4595
29431736Capturing the interactome of newly transcribed RNARIC & Hela2018 Feb 12Bao XDOI: 10.1038/nmeth.4595
22658674Insights into RNA biology from an atlas of mammalian mRNA-binding proteinsRIC & Hela2012 May 31Castello ADOI: 10.1016/j.cell.2012.04.031
30528433The Human RNA-Binding Proteome and Its Dynamics during Translational ArrestXRNAX & Hela2018 Dec 6Trendel JDOI: 10.1016/j.cell.2018.11.004
30607034Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)OOPS & MCF10A2019 Jan 3Queiroz RMLDOI: 10.1038/s41587-018-0001-2
30528433The Human RNA-Binding Proteome and Its Dynamics during Translational ArrestXRNAX & MCF72018 Dec 6Trendel JDOI: 10.1016/j.cell.2018.11.004
30607034Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)OOPS & U2OS2019 Jan 3Queiroz RMLDOI: 10.1038/s41587-018-0001-2
27453046Comprehensive Identification of RNA-Binding Domains in Human CellsRIC & Hela2016 Aug 18Castello ADOI: 10.1016/j.molcel.2016.06.029
30352994Discovery of RNA-binding proteins and characterization of their dynamic responses by enhanced RNA interactome captureRIC & Jurkat2018 Oct 23Perez-Perri JIDOI:10.1038/s41467-018-06557-8
Expression
Transcripts
Transcript IDNameLengthRefSeq ID Protein IDLengthRefSeq IDUniportKB ID
ENST00000367742PRRC2C-20210366XM_005245015ENSP000003567162819 (aa)XP_005245072E7EPN9
ENST00000495585PRRC2C-2115566-ENSP000004203821300 (aa)-H7C5N8
ENST00000647382PRRC2C-2144931-ENSP000004958671090 (aa)-A0A2R8YET2
ENST00000463586PRRC2C-2053771--- (aa)--
ENST00000492811PRRC2C-210379--- (aa)--
ENST00000338920PRRC2C-20110355XM_005245016ENSP000003436292817 (aa)XP_005245073Q9Y520
ENST00000498596PRRC2C-2121066-ENSP00000493580159 (aa)-A0A2R8Y424
ENST00000470689PRRC2C-207224--- (aa)--
ENST00000392078PRRC2C-2031919-ENSP00000375928299 (aa)-A0A0A0MS30
ENST00000426496PRRC2C-20410175-ENSP000004102192817 (aa)-Q9Y520
ENST00000480806PRRC2C-209299--- (aa)--
ENST00000476522PRRC2C-2081931--- (aa)--
ENST00000644916PRRC2C-2134331-ENSP00000495968910 (aa)-A0A2R8Y7F4
ENST00000467601PRRC2C-206717--- (aa)--
Gene Model
Click here to download ENSG00000117523's gene model file
Phenotypes
ensgIDTraitpValuePubmed ID
ENSG00000117523Hemoglobins3.336e-005-
ENSG00000117523Forced Expiratory Volume2.1680000E-005-
ENSG00000117523Forced Expiratory Volume2.1680000E-005-
ENSG00000117523Alzheimer Disease9E-723535033
GWAS
ensgIDSNPChromosomePositionSNP-risk TraitPubmedID95% CIOr or BEAT EFO ID
ENSG00000117523rs24218471171588461?Alzheimer's disease (cognitive decline)23535033unit decrease0.26EFO_0000249
ENSG00000117523rs347203811171486183?Creatinine levels29403010[0.027-0.056] unit increase novel0.0417EFO_0004518
ENSG00000117523rs347203811171486183?Glomerular filtration rate29403010[0.03-0.06] unit decrease novel0.045EFO_0005208
ENSG00000117523rs350393751171547724AEducational attainment (MTAG)30038396[0.014-0.023] unit increase0.0182EFO_0004784
ENSG00000117523rs350393751171547724AHighest math class taken (MTAG)30038396[0.013-0.024] unit increase0.0186EFO_0004875
ENSG00000117523rs347203811171486183TEducational attainment (years of education)30038396[0.013-0.023] unit decrease0.018EFO_0004784
ENSG00000117523rs350393751171547724AEducational attainment (years of education)30038396[0.013-0.023] unit increase0.0182EFO_0004784
ENSG00000117523rs350393751171547724?Educational attainment (years of education)30595370EFO_0004784
ENSG00000117523rs347203811171486183?Body mass index30595370EFO_0004340
Protein-Protein Interaction (PPI)

Clik here to download ENSG00000117523's network
Orthologs identified by RBPome
Ensembl IDGene SymbolCoverageIdentiy OrthologGene SymbolCoverageIdentiy Species
ENSG00000117523PRRC2C9360.362ENSDARG00000057583prrc2c7460.719Danio_rerio
ENSG00000117523PRRC2C6739.583ENSDARG00000031494prrc2a8173.750Danio_rerio
ENSG00000117523PRRC2C6050.685ENSG00000130723PRRC2B10057.895Homo_sapiens
ENSG00000117523PRRC2C9995.238ENSMUSG00000040225Prrc2c10095.455Mus_musculus
ENSG00000117523PRRC2C7235.671ENSMUSG00000039262Prrc2b7751.643Mus_musculus
Gene Ontology
Go IDGo_termPubmedIDEvidenceCategory
GO:0002244hematopoietic progenitor cell differentiation21873635.IBAProcess
GO:0003723RNA binding22658674.22681889.HDAFunction
GO:0005829cytosol-IDAComponent
GO:0008022protein C-terminus binding17577209.IPIFunction
GO:0016020membrane19946888.HDAComponent

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