EuRBPDB

Description

Ensembl ID: ENSG00000119041 (Gene tree)
Gene ID: 9330
Gene Symbol: GTF3C3
Alias: TFiiiC2-102|TFIIIC102
Full Name: general transcription factor IIIC subunit 3
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Minus strand
Length: 36,737 bases
Position: chr2:196,763,032-196,799,768
Accession: 4666
RBP type: non-canonical RBP
Summary: The protein encoded by this gene is part of the TFIIIC2 complex, which binds to the promoters of small nuclear and cytoplasmic RNA genes in order to recruit RNA polymerase III. The TFIIIC2 complex is composed of six subunits. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
29431736	Capturing the interactome of newly transcribed RNA	PolyT-RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
10373544	Cloning and characterization of two evolutionarily conserved subunits (TFIIIC102 and TFIIIC63) of human TFIIIC and their involvement in functional interactions with TFIIIB and RNA polymerase III.	Mol Cell Biol	1999 Jul	Hsieh YJ	-

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000455546	GTF3C3-208	547	-	ENSP00000389992	6 (aa)	-	UPI000204A859
ENST00000416690	GTF3C3-203	326	-	ENSP00000391724	109 (aa)	-	H7BZV8
ENST00000470386	GTF3C3-210	713	-	-	- (aa)	-	-
ENST00000481098	GTF3C3-211	547	-	-	- (aa)	-	-
ENST00000409364	GTF3C3-202	1736	-	ENSP00000386465	413 (aa)	-	Q9Y5Q9
ENST00000263956	GTF3C3-201	4282	XM_005246965	ENSP00000263956	886 (aa)	XP_005247022	Q9Y5Q9
ENST00000466862	GTF3C3-209	447	-	-	- (aa)	-	-
ENST00000451088	GTF3C3-207	488	-	ENSP00000438797	44 (aa)	-	H0YFI7
ENST00000435252	GTF3C3-204	527	-	ENSP00000394065	148 (aa)	-	H7C0C0
ENST00000448087	GTF3C3-205	1702	-	ENSP00000398385	161 (aa)	-	H7C143
ENST00000448539	GTF3C3-206	796	-	ENSP00000406685	38 (aa)	-	F8WC64

Gene Model

Protein-Protein Interaction (PPI)

* RBP PPI network refers to all genes directly bind to RBP

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000127	transcription factor TFIIIC complex	21873635.	IBA	Component
GO:0000127	transcription factor TFIIIC complex	17409385.	IDA	Component
GO:0000995	RNA polymerase III general transcription initiation factor activity	21873635.	IBA	Function
GO:0001004	RNA polymerase III transcription regulator recruiting activity	-	IEA	Function
GO:0003677	DNA binding	17409385.	IC	Function
GO:0005515	protein binding	17500595.	IPI	Function
GO:0005634	nucleus	-	IDA	Component
GO:0005654	nucleoplasm	-	TAS	Component
GO:0005730	nucleolus	-	IDA	Component
GO:0006383	transcription by RNA polymerase III	21873635.	IBA	Process
GO:0006383	transcription by RNA polymerase III	17409385.	IC	Process
GO:0031965	nuclear membrane	-	IDA	Component
GO:0042791	5S class rRNA transcription by RNA polymerase III	17409385.	IC	Process
GO:0042797	tRNA transcription by RNA polymerase III	17409385.	IC	Process
GO:0070898	RNA polymerase III preinitiation complex assembly	-	IEA	Process