EuRBPDB

Description

RBPome

Literatures

Expression

Transcripts

Gene Model

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000119596 (Gene tree)
Gene ID: 56252
Gene Symbol: YLPM1
Alias: ZAP|PPP1R169|C14orf170
Full Name: YLP motif containing 1
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Plus strand
Length: 96,114 bases
Position: chr14:74,763,322-74,859,435
Accession: 17798
RBP type: non-canonical RBP
Summary: (YLP Motif Containing 1) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include 6-phosphofructo-2-kinase activity.

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
22681889	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts	4SURIC & HEK293	2012 May	Baltz AG	DOI: 10.1016/j.molcel.2012.05.021
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
29431736	Capturing the interactome of newly transcribed RNA	NascentRICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	PolyT-RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	RIC & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
17890166	The nuclear PP1 interacting protein ZAP3 (ZAP) is a putative nucleoside kinase that complexes with SAM68, CIA, NF110/45, and HNRNP-G.	Biochim Biophys Acta	2007 Oct	Ulke-Lemee A	-

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000547879	YLPM1-203	2316	-	ENSP00000448367	466 (aa)	-	H0YI23
ENST00000554107	YLPM1-209	4424	-	ENSP00000476212	110 (aa)	-	U3KQT9
ENST00000552421	YLPM1-207	4899	XM_011536967	ENSP00000447921	1440 (aa)	XP_011535269	F8VU51
ENST00000546901	YLPM1-202	800	-	-	- (aa)	-	-
ENST00000325680	YLPM1-201	7108	XM_005267860	ENSP00000324463	2146 (aa)	XP_005267917	P49750
ENST00000553381	YLPM1-208	696	-	-	- (aa)	-	-
ENST00000549197	YLPM1-204	2085	-	-	- (aa)	-	-
ENST00000549293	YLPM1-205	5500	-	ENSP00000449860	1595 (aa)	-	H0YIQ2
ENST00000550021	YLPM1-206	407	-	-	- (aa)	-	-

Gene Model

Click here to download ENSG00000119596's gene model file

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000119596	Longevity	6E-6	27015805

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000119596	rs397852991	14	74802218	C	Mood instability	29187730	[0.036-0.07] unit increase	0.053	EFO_0008475
ENSG00000119596	rs397852991	14	74802218	C	Mood instability	29187730	[0.027-0.063] unit increase	0.045	EFO_0008475
ENSG00000119596	rs5809679	14	74816171	?	Parental longevity (combined parental age at death)	27015805	[0.021-0.054] unit increase	0.037788	EFO_0007796
ENSG00000119596	rs2270431	14	74803932	T	Neuroticism	29255261	z score decrease	7.292	EFO_0007660
ENSG00000119596	rs12896360	14	74811478	A	Experiencing mood swings	29500382	z score decrease	5.76	EFO_0008475
ENSG00000119596	rs10144845	14	74771067	T	Feeling fed-up	29500382	z score increase	6.12	EFO_0009588
ENSG00000119596	rs2193596	14	74767398	T	Suffering from nerves	29500382	z score decrease	5.86	NCIT_C74532
ENSG00000119596	rs8014204	14	74856091	A	Caffeine consumption	21490707	[0.04-0.10] mg/day increase	0.065	EFO_0004330
ENSG00000119596	rs10148293	14	74830128	G	Depression (broad)	29662059	[0.0038-0.0086] unit increase	0.0062	EFO_0003761
ENSG00000119596	rs10144845	14	74771067	C	Depressed affect	29942085	[0.011-0.021] unit decrease	0.01604	EFO_0003761\|EFO_0004247
ENSG00000119596	rs61978928	14	74855011	T	Parental longevity (both parents in top 10%)	29227965			EFO_0007796
ENSG00000119596	rs10144845	14	74771067	T	Neurociticism	29500382	z score increase	7.4	EFO_0007660
ENSG00000119596	rs7144654	14	74831934	A	Neuroticism	29942085	z score decrease	7.208	EFO_0007660
ENSG00000119596	rs12588415	14	74811508	G	Low density lipoprotein cholesterol levels	29507422	unit increase	0.015	EFO_0004611
ENSG00000119596	rs12588415	14	74811508	G	Total cholesterol levels	29507422	unit increase	0.018	EFO_0004574
ENSG00000119596	rs973879	14	74831024	?	Macular thickness	30535121	[0.56-0.83] unit decrease	0.692	EFO_0008375
ENSG00000119596	rs61978928	14	74855011	T	Parental longevity (father's attained age)	29227965			EFO_0007796
ENSG00000119596	rs2058919	14	74844109	?	Red cell distribution width	30595370			EFO_0005192
ENSG00000119596	rs12588415	14	74811508	G	Low density lipoprotein cholesterol levels	29507422	unit increase	0.019	EFO_0004611
ENSG00000119596	rs12588415	14	74811508	G	Low density lipoprotein cholesterol levels	29507422	unit increase	0.022	EFO_0004611
ENSG00000119596	rs12588415	14	74811508	G	Total cholesterol levels	29507422	unit increase	0.019	EFO_0004574
ENSG00000119596	rs12588415	14	74811508	G	Total cholesterol levels	29507422	unit increase	0.022	EFO_0004574
ENSG00000119596	rs45599947	14	74764250	T	Neuroticism	30643256	[0.01-0.021] unit increase	0.015483722	EFO_0007660
ENSG00000119596	rs45599947	14	74764250	T	Depressive symptoms	30643256	[0.0064-0.0134] unit increase	0.00990448	EFO_0007006
ENSG00000119596	rs45599947	14	74764250	T	Positive affect	30643256	[0.0077-0.0161] unit increase	0.01190613	EFO_0007869

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000119596's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs identified by RBPome

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000119596	YLPM1	100	93.098	ENSMUSG00000021244	Ylpm1	100	86.938	Mus_musculus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0003723	RNA binding	22681889.	HDA	Function
GO:0005515	protein binding	21873635.	IBA	Function
GO:0005515	protein binding	21078624.22321011.28330616.	IPI	Function
GO:0005634	nucleus	21873635.	IBA	Component
GO:0005634	nucleus	17890166.	IDA	Component
GO:0005654	nucleoplasm	-	IDA	Component
GO:0005829	cytosol	-	IDA	Component
GO:0008150	biological_process	-	ND	Process
GO:0016607	nuclear speck	-	IDA	Component