EuRBPDB

Description

RBDs

RBPome

Expression

Transcripts

Gene Model

Pathways

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000120333 (Gene tree)
Gene ID: 63931
Gene Symbol: MRPS14
Alias: HSMRPS14
Full Name: mitochondrial ribosomal protein S14
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Minus strand
Length: 12,667 bases
Position: chr1:175,010,789-175,023,455
Accession: 14049
RBP type: canonical RBP
Summary: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S14P family. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2010]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000420714	Ribosomal_S14	PF00253.21	2.3e-22	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
22681889	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts	4SURIC & HEK293	2012 May	Baltz AG	DOI: 10.1016/j.molcel.2012.05.021
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000498253	MRPS14-203	539	-	-	- (aa)	-	-
ENST00000367677	MRPS14-201	910	-	ENSP00000431220	60 (aa)	-	F2Z361
ENST00000476371	MRPS14-202	2115	-	ENSP00000420714	128 (aa)	-	O60783

Gene Model

Click here to download ENSG00000120333's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa03010	Ribosome	KEGG

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000120333's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000120333	MRPS14	100	72.932	ENSAPOG00000016098	mrps14	96	72.932	Acanthochromis_polyacanthus
ENSG00000120333	MRPS14	100	83.594	ENSAMEG00000000175	MRPS14	100	83.594	Ailuropoda_melanoleuca
ENSG00000120333	MRPS14	100	72.932	ENSACIG00000013818	mrps14	96	72.932	Amphilophus_citrinellus
ENSG00000120333	MRPS14	85	81.651	ENSAOCG00000016515	mrps14	74	81.651	Amphiprion_ocellaris
ENSG00000120333	MRPS14	85	81.651	ENSAPEG00000008095	mrps14	79	81.651	Amphiprion_percula
ENSG00000120333	MRPS14	85	82.569	ENSATEG00000012233	mrps14	54	82.569	Anabas_testudineus
ENSG00000120333	MRPS14	100	73.643	ENSACAG00000023212	MRPS14	100	73.643	Anolis_carolinensis
ENSG00000120333	MRPS14	100	89.844	ENSANAG00000036400	MRPS14	100	89.844	Aotus_nancymaae
ENSG00000120333	MRPS14	85	83.486	ENSACLG00000026797	mrps14	71	83.486	Astatotilapia_calliptera
ENSG00000120333	MRPS14	82	80.952	ENSAMXG00000035845	mrps14	79	80.952	Astyanax_mexicanus
ENSG00000120333	MRPS14	100	90.625	ENSBTAG00000001109	MRPS14	100	90.625	Bos_taurus
ENSG00000120333	MRPS14	84	40.187	WBGene00011334	mrps-14	54	40.187	Caenorhabditis_elegans
ENSG00000120333	MRPS14	100	92.188	ENSCJAG00000008986	-	100	92.188	Callithrix_jacchus
ENSG00000120333	MRPS14	100	91.406	ENSCJAG00000035652	-	100	91.406	Callithrix_jacchus
ENSG00000120333	MRPS14	98	86.400	ENSCAFG00000006477	-	100	86.400	Canis_familiaris
ENSG00000120333	MRPS14	100	89.844	ENSCAFG00000014370	-	100	89.844	Canis_familiaris
ENSG00000120333	MRPS14	100	89.844	ENSCAFG00020017090	-	100	89.844	Canis_lupus_dingo
ENSG00000120333	MRPS14	98	86.508	ENSCAFG00020021667	-	98	86.508	Canis_lupus_dingo
ENSG00000120333	MRPS14	100	85.156	ENSCHIG00000009993	MRPS14	100	85.156	Capra_hircus
ENSG00000120333	MRPS14	100	89.844	ENSTSYG00000033746	MRPS14	100	89.844	Carlito_syrichta
ENSG00000120333	MRPS14	91	85.345	ENSCAPG00000008898	MRPS14	100	85.345	Cavia_aperea
ENSG00000120333	MRPS14	100	87.500	ENSCPOG00000033627	MRPS14	100	87.500	Cavia_porcellus
ENSG00000120333	MRPS14	100	92.188	ENSCCAG00000023517	MRPS14	100	92.188	Cebus_capucinus
ENSG00000120333	MRPS14	100	98.438	ENSCATG00000037150	MRPS14	100	98.438	Cercocebus_atys
ENSG00000120333	MRPS14	100	89.062	ENSCLAG00000013217	MRPS14	100	89.062	Chinchilla_lanigera
ENSG00000120333	MRPS14	100	98.438	ENSCSAG00000011897	MRPS14	100	98.438	Chlorocebus_sabaeus
ENSG00000120333	MRPS14	100	53.906	ENSCHOG00000008979	MRPS14	100	53.906	Choloepus_hoffmanni
ENSG00000120333	MRPS14	88	82.301	ENSCPBG00000014641	MRPS14	71	82.301	Chrysemys_picta_bellii
ENSG00000120333	MRPS14	86	47.273	ENSCING00000018529	-	86	47.273	Ciona_intestinalis
ENSG00000120333	MRPS14	100	98.438	ENSCANG00000030299	MRPS14	100	98.438	Colobus_angolensis_palliatus
ENSG00000120333	MRPS14	100	85.938	ENSCGRG00001024975	Mrps14	100	85.938	Cricetulus_griseus_chok1gshd
ENSG00000120333	MRPS14	100	85.938	ENSCGRG00000008868	Mrps14	100	85.938	Cricetulus_griseus_crigri
ENSG00000120333	MRPS14	100	72.932	ENSCSEG00000016424	mrps14	96	72.932	Cynoglossus_semilaevis
ENSG00000120333	MRPS14	100	73.438	ENSCVAG00000009447	mrps14	100	73.438	Cyprinodon_variegatus
ENSG00000120333	MRPS14	87	78.378	ENSDARG00000068305	mrps14	80	78.378	Danio_rerio
ENSG00000120333	MRPS14	100	89.844	ENSDNOG00000039337	MRPS14	99	89.844	Dasypus_novemcinctus
ENSG00000120333	MRPS14	100	86.719	ENSDORG00000001869	Mrps14	100	86.719	Dipodomys_ordii
ENSG00000120333	MRPS14	89	63.793	FBgn0044030	mRpS14	91	63.793	Drosophila_melanogaster
ENSG00000120333	MRPS14	100	87.500	ENSETEG00000013936	MRPS14	100	87.500	Echinops_telfairi
ENSG00000120333	MRPS14	74	86.316	ENSEBUG00000012209	mrps14	100	86.316	Eptatretus_burgeri
ENSG00000120333	MRPS14	100	90.625	ENSEASG00005016976	MRPS14	96	90.625	Equus_asinus_asinus
ENSG00000120333	MRPS14	100	90.625	ENSECAG00000011077	MRPS14	100	90.625	Equus_caballus
ENSG00000120333	MRPS14	88	88.496	ENSEEUG00000006121	MRPS14	100	88.496	Erinaceus_europaeus
ENSG00000120333	MRPS14	85	84.404	ENSELUG00000011585	mrps14	78	84.404	Esox_lucius
ENSG00000120333	MRPS14	100	90.625	ENSFCAG00000041109	MRPS14	100	90.625	Felis_catus
ENSG00000120333	MRPS14	90	79.130	ENSFALG00000008407	MRPS14	100	75.781	Ficedula_albicollis
ENSG00000120333	MRPS14	100	85.938	ENSFDAG00000014393	MRPS14	100	85.938	Fukomys_damarensis
ENSG00000120333	MRPS14	99	77.165	ENSFHEG00000022227	mrps14	95	77.165	Fundulus_heteroclitus
ENSG00000120333	MRPS14	82	85.714	ENSGMOG00000012620	mrps14	85	85.714	Gadus_morhua
ENSG00000120333	MRPS14	100	77.344	ENSGALG00000030028	MRPS14	100	77.344	Gallus_gallus
ENSG00000120333	MRPS14	100	71.429	ENSGAFG00000010744	mrps14	96	71.429	Gambusia_affinis
ENSG00000120333	MRPS14	94	78.689	ENSGACG00000013755	mrps14	94	78.689	Gasterosteus_aculeatus
ENSG00000120333	MRPS14	100	79.688	ENSGAGG00000021491	MRPS14	96	79.688	Gopherus_agassizii
ENSG00000120333	MRPS14	100	100.000	ENSGGOG00000005966	MRPS14	100	100.000	Gorilla_gorilla
ENSG00000120333	MRPS14	85	83.486	ENSHBUG00000003003	mrps14	73	83.486	Haplochromis_burtoni
ENSG00000120333	MRPS14	100	88.281	ENSHGLG00000005689	MRPS14	100	88.281	Heterocephalus_glaber_female
ENSG00000120333	MRPS14	100	88.281	ENSHGLG00100005382	MRPS14	100	88.281	Heterocephalus_glaber_male
ENSG00000120333	MRPS14	82	84.762	ENSHCOG00000009308	mrps14	76	84.762	Hippocampus_comes
ENSG00000120333	MRPS14	97	75.397	ENSIPUG00000018252	mrps14	95	75.397	Ictalurus_punctatus
ENSG00000120333	MRPS14	100	86.719	ENSSTOG00000025353	MRPS14	100	86.719	Ictidomys_tridecemlineatus
ENSG00000120333	MRPS14	100	84.375	ENSJJAG00000005950	Mrps14	100	84.375	Jaculus_jaculus
ENSG00000120333	MRPS14	100	72.180	ENSKMAG00000010949	mrps14	96	72.180	Kryptolebias_marmoratus
ENSG00000120333	MRPS14	85	84.404	ENSLBEG00000017686	mrps14	79	84.404	Labrus_bergylta
ENSG00000120333	MRPS14	97	71.875	ENSLACG00000009527	MRPS14	90	71.875	Latimeria_chalumnae
ENSG00000120333	MRPS14	82	84.762	ENSLOCG00000002424	mrps14	89	84.762	Lepisosteus_oculatus
ENSG00000120333	MRPS14	100	88.281	ENSLAFG00000012916	MRPS14	100	88.281	Loxodonta_africana
ENSG00000120333	MRPS14	100	98.438	ENSMFAG00000044095	MRPS14	100	98.438	Macaca_fascicularis
ENSG00000120333	MRPS14	100	99.219	ENSMMUG00000001573	MRPS14	100	99.219	Macaca_mulatta
ENSG00000120333	MRPS14	99	85.938	ENSMNEG00000045113	MRPS14	100	85.938	Macaca_nemestrina
ENSG00000120333	MRPS14	100	99.219	ENSMLEG00000036873	MRPS14	100	99.219	Mandrillus_leucophaeus
ENSG00000120333	MRPS14	85	84.404	ENSMAMG00000012048	mrps14	79	84.404	Mastacembelus_armatus
ENSG00000120333	MRPS14	85	83.486	ENSMZEG00005025480	mrps14	71	83.486	Maylandia_zebra
ENSG00000120333	MRPS14	100	76.562	ENSMGAG00000002127	MRPS14	100	76.562	Meleagris_gallopavo
ENSG00000120333	MRPS14	100	85.938	ENSMAUG00000018062	Mrps14	100	85.938	Mesocricetus_auratus
ENSG00000120333	MRPS14	100	91.406	ENSMICG00000037413	MRPS14	100	91.406	Microcebus_murinus
ENSG00000120333	MRPS14	100	87.500	ENSMOCG00000019730	Mrps14	100	87.500	Microtus_ochrogaster
ENSG00000120333	MRPS14	85	84.404	ENSMMOG00000018953	mrps14	84	84.404	Mola_mola
ENSG00000120333	MRPS14	100	84.375	ENSMODG00000004390	MRPS14	100	84.375	Monodelphis_domestica
ENSG00000120333	MRPS14	100	74.436	ENSMALG00000017066	mrps14	96	74.436	Monopterus_albus
ENSG00000120333	MRPS14	100	86.719	MGP_CAROLIEiJ_G0014753	Mrps14	100	86.719	Mus_caroli
ENSG00000120333	MRPS14	100	86.719	ENSMUSG00000058267	Mrps14	100	86.719	Mus_musculus
ENSG00000120333	MRPS14	100	85.156	MGP_PahariEiJ_G0027989	Mrps14	100	85.156	Mus_pahari
ENSG00000120333	MRPS14	100	86.719	MGP_SPRETEiJ_G0015560	Mrps14	100	86.719	Mus_spretus
ENSG00000120333	MRPS14	97	91.129	ENSMPUG00000004861	MRPS14	95	91.129	Mustela_putorius_furo
ENSG00000120333	MRPS14	100	90.625	ENSMLUG00000022294	MRPS14	100	90.625	Myotis_lucifugus
ENSG00000120333	MRPS14	100	89.062	ENSNGAG00000013183	Mrps14	100	89.062	Nannospalax_galili
ENSG00000120333	MRPS14	85	83.486	ENSNBRG00000016055	mrps14	79	83.486	Neolamprologus_brichardi
ENSG00000120333	MRPS14	100	98.438	ENSNLEG00000034565	MRPS14	100	98.438	Nomascus_leucogenys
ENSG00000120333	MRPS14	88	88.496	ENSMEUG00000010723	MRPS14	100	88.496	Notamacropus_eugenii
ENSG00000120333	MRPS14	87	90.991	ENSOPRG00000000318	-	98	90.991	Ochotona_princeps
ENSG00000120333	MRPS14	100	90.625	ENSODEG00000011705	MRPS14	100	90.625	Octodon_degus
ENSG00000120333	MRPS14	85	83.486	ENSONIG00000009916	mrps14	78	83.486	Oreochromis_niloticus
ENSG00000120333	MRPS14	100	82.031	ENSOANG00000000931	MRPS14	100	82.031	Ornithorhynchus_anatinus
ENSG00000120333	MRPS14	100	85.938	ENSOCUG00000026497	-	100	85.938	Oryctolagus_cuniculus
ENSG00000120333	MRPS14	99	77.953	ENSOCUG00000027982	-	99	77.953	Oryctolagus_cuniculus
ENSG00000120333	MRPS14	85	84.404	ENSORLG00000016235	mrps14	78	84.404	Oryzias_latipes
ENSG00000120333	MRPS14	85	83.486	ENSORLG00015013762	mrps14	79	83.486	Oryzias_latipes_hsok
ENSG00000120333	MRPS14	85	81.651	ENSOMEG00000023365	mrps14	79	81.651	Oryzias_melastigma
ENSG00000120333	MRPS14	100	88.281	ENSOGAG00000007741	MRPS14	100	88.281	Otolemur_garnettii
ENSG00000120333	MRPS14	100	91.406	ENSOARG00000013810	MRPS14	100	91.406	Ovis_aries
ENSG00000120333	MRPS14	100	100.000	ENSPPAG00000030459	MRPS14	100	100.000	Pan_paniscus
ENSG00000120333	MRPS14	100	90.625	ENSPPRG00000002784	MRPS14	100	90.625	Panthera_pardus
ENSG00000120333	MRPS14	100	90.625	ENSPTIG00000010737	MRPS14	100	90.625	Panthera_tigris_altaica
ENSG00000120333	MRPS14	100	100.000	ENSPTRG00000045279	MRPS14	100	100.000	Pan_troglodytes
ENSG00000120333	MRPS14	100	99.219	ENSPANG00000025213	MRPS14	100	99.219	Papio_anubis
ENSG00000120333	MRPS14	96	76.423	ENSPKIG00000023947	mrps14	95	76.423	Paramormyrops_kingsleyae
ENSG00000120333	MRPS14	98	73.810	ENSPSIG00000014883	MRPS14	97	73.810	Pelodiscus_sinensis
ENSG00000120333	MRPS14	96	76.800	ENSPMGG00000015195	mrps14	91	76.800	Periophthalmus_magnuspinnatus
ENSG00000120333	MRPS14	90	84.483	ENSPEMG00000012879	-	100	84.483	Peromyscus_maniculatus_bairdii
ENSG00000120333	MRPS14	87	82.883	ENSPMAG00000007304	mrps14	80	82.883	Petromyzon_marinus
ENSG00000120333	MRPS14	100	83.594	ENSPCIG00000001547	MRPS14	100	83.594	Phascolarctos_cinereus
ENSG00000120333	MRPS14	100	72.180	ENSPFOG00000006389	mrps14	96	72.180	Poecilia_formosa
ENSG00000120333	MRPS14	100	72.180	ENSPLAG00000016949	mrps14	96	72.180	Poecilia_latipinna
ENSG00000120333	MRPS14	100	72.180	ENSPMEG00000007811	mrps14	96	72.180	Poecilia_mexicana
ENSG00000120333	MRPS14	96	76.000	ENSPREG00000002401	mrps14	96	76.000	Poecilia_reticulata
ENSG00000120333	MRPS14	100	96.875	ENSPPYG00000000485	MRPS14	100	96.875	Pongo_abelii
ENSG00000120333	MRPS14	100	90.625	ENSPCAG00000003778	MRPS14	100	90.625	Procavia_capensis
ENSG00000120333	MRPS14	100	92.969	ENSPCOG00000020231	MRPS14	100	92.969	Propithecus_coquereli
ENSG00000120333	MRPS14	100	89.062	ENSPVAG00000001982	MRPS14	100	89.062	Pteropus_vampyrus
ENSG00000120333	MRPS14	85	83.486	ENSPNYG00000010650	mrps14	79	83.486	Pundamilia_nyererei
ENSG00000120333	MRPS14	97	75.397	ENSPNAG00000003065	mrps14	91	75.397	Pygocentrus_nattereri
ENSG00000120333	MRPS14	100	85.938	ENSRNOG00000002569	Mrps14	100	85.938	Rattus_norvegicus
ENSG00000120333	MRPS14	100	97.656	ENSRBIG00000038405	-	100	97.656	Rhinopithecus_bieti
ENSG00000120333	MRPS14	100	97.656	ENSRROG00000044175	MRPS14	100	97.656	Rhinopithecus_roxellana
ENSG00000120333	MRPS14	78	30.097	YPR166C	-	87	30.097	Saccharomyces_cerevisiae
ENSG00000120333	MRPS14	98	92.063	ENSSBOG00000020487	MRPS14	82	92.063	Saimiri_boliviensis_boliviensis
ENSG00000120333	MRPS14	100	85.938	ENSSHAG00000013210	MRPS14	100	85.938	Sarcophilus_harrisii
ENSG00000120333	MRPS14	87	81.081	ENSSFOG00015019312	mrps14	79	81.081	Scleropages_formosus
ENSG00000120333	MRPS14	82	81.905	ENSSMAG00000000475	mrps14	76	81.905	Scophthalmus_maximus
ENSG00000120333	MRPS14	82	81.905	ENSSDUG00000019344	mrps14	76	81.905	Seriola_dumerili
ENSG00000120333	MRPS14	82	81.905	ENSSLDG00000013093	mrps14	76	81.905	Seriola_lalandi_dorsalis
ENSG00000120333	MRPS14	100	73.438	ENSSPUG00000005848	MRPS14	100	73.438	Sphenodon_punctatus
ENSG00000120333	MRPS14	89	79.487	ENSSPAG00000000794	mrps14	89	79.487	Stegastes_partitus
ENSG00000120333	MRPS14	100	90.625	ENSSSCG00000031435	MRPS14	100	92.920	Sus_scrofa
ENSG00000120333	MRPS14	88	83.186	ENSTGUG00000003271	MRPS14	100	83.186	Taeniopygia_guttata
ENSG00000120333	MRPS14	85	85.321	ENSTNIG00000015252	mrps14	79	85.321	Tetraodon_nigroviridis
ENSG00000120333	MRPS14	100	92.188	ENSTBEG00000003335	MRPS14	100	92.188	Tupaia_belangeri
ENSG00000120333	MRPS14	100	90.625	ENSTTRG00000010408	MRPS14	100	90.625	Tursiops_truncatus
ENSG00000120333	MRPS14	100	90.625	ENSUAMG00000019055	MRPS14	100	90.625	Ursus_americanus
ENSG00000120333	MRPS14	100	90.625	ENSUMAG00000020182	MRPS14	100	90.625	Ursus_maritimus
ENSG00000120333	MRPS14	100	92.969	ENSVPAG00000008685	MRPS14	100	92.969	Vicugna_pacos
ENSG00000120333	MRPS14	83	91.509	ENSVVUG00000014099	MRPS14	98	84.800	Vulpes_vulpes
ENSG00000120333	MRPS14	100	74.809	ENSXETG00000020045	mrps14	100	74.809	Xenopus_tropicalis
ENSG00000120333	MRPS14	100	70.677	ENSXMAG00000022794	mrps14	96	70.677	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0003723	RNA binding	22681889.	HDA	Function
GO:0003735	structural constituent of ribosome	21873635.	IBA	Function
GO:0003735	structural constituent of ribosome	10938081.	TAS	Function
GO:0005743	mitochondrial inner membrane	-	TAS	Component
GO:0005761	mitochondrial ribosome	10938081.	NAS	Component
GO:0005763	mitochondrial small ribosomal subunit	21873635.	IBA	Component
GO:0005763	mitochondrial small ribosomal subunit	25838379.	IDA	Component
GO:0006412	translation	10938081.	NAS	Process
GO:0070125	mitochondrial translational elongation	-	TAS	Process
GO:0070126	mitochondrial translational termination	-	TAS	Process