EuRBPDB

Description

RBDs

RBPome

Expression

Transcripts

Gene Model

GWAS

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000121486 (Gene tree)
Gene ID: 81627
Gene Symbol: TRMT1L
Alias: C1orf25
Full Name: tRNA methyltransferase 1 like
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Minus strand
Length: 39,014 bases
Position: chr1:185,118,085-185,157,098
Accession: 16782
RBP type: canonical RBP
Summary: This gene encodes a protein that has some similarity to N2,N2-dimethylguanosine tRNA methyltransferase from other organisms. Studies of the mouse ortholog have shown that this protein plays a role in motor coordination and exploratory behavior, and it may also be involved in modulating postnatal neuronal functions. Alternatively spliced transcripts have been identified for this gene. [provided by RefSeq, Jan 2011]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000356476	TRM	PF02005.16	1.3e-65	1	2
ENSP00000356476	TRM	PF02005.16	1.3e-65	2	2
ENSP00000414339	TRM	PF02005.16	1.9e-28	1	1
ENSP00000356476	Met_10	PF02475.16	0.00058	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
29431736	Capturing the interactome of newly transcribed RNA	PolyT-RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
22658674	Insights into RNA biology from an atlas of mammalian mRNA-binding proteins	RIC & Hela	2012 May 31	Castello A	DOI: 10.1016/j.cell.2012.04.031
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30352994	Discovery of RNA-binding proteins and characterization of their dynamic responses by enhanced RNA interactome capture	RIC & Jurkat	2018 Oct 23	Perez-Perri JI	DOI:10.1038/s41467-018-06557-8

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000487028	TRMT1L-204	619	-	-	- (aa)	-	-
ENST00000458395	TRMT1L-202	735	-	ENSP00000414339	212 (aa)	-	X6RK96
ENST00000367506	TRMT1L-201	4392	XM_017002419	ENSP00000356476	733 (aa)	XP_016857908	Q7Z2T5
ENST00000465827	TRMT1L-203	706	-	-	- (aa)	-	-

Gene Model

Click here to download ENSG00000121486's gene model file

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000121486	rs6424971	1	185141235	T	Hand grip strength	29691431	[0.0014-0.0026] unit increase	0.002	EFO_0006941

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000121486's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000121486	TRMT1L	99	70.616	ENSAPOG00000011807	trmt1l	99	57.837	Acanthochromis_polyacanthus
ENSG00000121486	TRMT1L	99	98.571	ENSAMEG00000013538	TRMT1L	100	94.150	Ailuropoda_melanoleuca
ENSG00000121486	TRMT1L	99	71.564	ENSACIG00000012049	trmt1l	96	62.651	Amphilophus_citrinellus
ENSG00000121486	TRMT1L	100	69.811	ENSAOCG00000018112	trmt1l	99	61.538	Amphiprion_ocellaris
ENSG00000121486	TRMT1L	100	70.283	ENSAPEG00000021433	trmt1l	99	60.836	Amphiprion_percula
ENSG00000121486	TRMT1L	92	75.258	ENSATEG00000004573	trmt1l	99	63.889	Anabas_testudineus
ENSG00000121486	TRMT1L	99	80.476	ENSAPLG00000008394	TRMT1L	99	70.940	Anas_platyrhynchos
ENSG00000121486	TRMT1L	99	80.952	ENSACAG00000002342	TRMT1L	87	73.709	Anolis_carolinensis
ENSG00000121486	TRMT1L	99	98.571	ENSANAG00000038162	TRMT1L	100	97.271	Aotus_nancymaae
ENSG00000121486	TRMT1L	99	70.952	ENSACLG00000021625	trmt1l	93	61.137	Astatotilapia_calliptera
ENSG00000121486	TRMT1L	99	72.857	ENSAMXG00000009602	trmt1l	91	62.117	Astyanax_mexicanus
ENSG00000121486	TRMT1L	99	97.129	ENSBTAG00000011285	TRMT1L	100	90.958	Bos_taurus
ENSG00000121486	TRMT1L	99	97.619	ENSCJAG00000005456	TRMT1L	100	94.952	Callithrix_jacchus
ENSG00000121486	TRMT1L	99	98.571	ENSCAFG00000013518	TRMT1L	98	94.278	Canis_familiaris
ENSG00000121486	TRMT1L	99	98.571	ENSCAFG00020015640	TRMT1L	100	94.286	Canis_lupus_dingo
ENSG00000121486	TRMT1L	99	98.095	ENSCHIG00000016522	TRMT1L	100	91.498	Capra_hircus
ENSG00000121486	TRMT1L	99	97.143	ENSTSYG00000010465	TRMT1L	100	92.906	Carlito_syrichta
ENSG00000121486	TRMT1L	72	91.304	ENSCAPG00000012562	TRMT1L	89	90.942	Cavia_aperea
ENSG00000121486	TRMT1L	99	96.667	ENSCPOG00000001567	TRMT1L	98	90.436	Cavia_porcellus
ENSG00000121486	TRMT1L	99	99.048	ENSCCAG00000018699	TRMT1L	100	96.862	Cebus_capucinus
ENSG00000121486	TRMT1L	100	98.503	ENSCATG00000043114	TRMT1L	100	98.503	Cercocebus_atys
ENSG00000121486	TRMT1L	98	86.538	ENSCLAG00000010853	-	96	73.566	Chinchilla_lanigera
ENSG00000121486	TRMT1L	99	97.619	ENSCLAG00000010801	-	98	92.264	Chinchilla_lanigera
ENSG00000121486	TRMT1L	100	98.503	ENSCSAG00000012880	TRMT1L	100	98.503	Chlorocebus_sabaeus
ENSG00000121486	TRMT1L	73	99.351	ENSCHOG00000011164	TRMT1L	89	79.688	Choloepus_hoffmanni
ENSG00000121486	TRMT1L	99	83.333	ENSCPBG00000015694	TRMT1L	93	76.328	Chrysemys_picta_bellii
ENSG00000121486	TRMT1L	100	97.959	ENSCANG00000031107	TRMT1L	100	97.959	Colobus_angolensis_palliatus
ENSG00000121486	TRMT1L	99	96.190	ENSCGRG00001019297	Trmt1l	100	87.619	Cricetulus_griseus_chok1gshd
ENSG00000121486	TRMT1L	99	96.190	ENSCGRG00000005036	Trmt1l	100	87.619	Cricetulus_griseus_crigri
ENSG00000121486	TRMT1L	99	70.616	ENSCSEG00000001248	trmt1l	95	60.535	Cynoglossus_semilaevis
ENSG00000121486	TRMT1L	99	71.564	ENSCVAG00000012274	trmt1l	96	59.939	Cyprinodon_variegatus
ENSG00000121486	TRMT1L	99	70.952	ENSDARG00000042057	trmt1l	95	63.339	Danio_rerio
ENSG00000121486	TRMT1L	99	97.619	ENSDNOG00000005239	TRMT1L	100	91.429	Dasypus_novemcinctus
ENSG00000121486	TRMT1L	99	96.190	ENSDORG00000003298	Trmt1l	99	91.312	Dipodomys_ordii
ENSG00000121486	TRMT1L	73	100.000	ENSETEG00000015895	TRMT1L	91	80.717	Echinops_telfairi
ENSG00000121486	TRMT1L	93	62.944	ENSEBUG00000010301	trmt1l	97	47.907	Eptatretus_burgeri
ENSG00000121486	TRMT1L	99	98.578	ENSEASG00005005551	TRMT1L	100	89.218	Equus_asinus_asinus
ENSG00000121486	TRMT1L	99	98.571	ENSECAG00000020999	TRMT1L	95	92.973	Equus_caballus
ENSG00000121486	TRMT1L	99	75.787	ENSEEUG00000014110	TRMT1L	95	80.330	Erinaceus_europaeus
ENSG00000121486	TRMT1L	99	74.762	ENSELUG00000020587	trmt1l	88	63.968	Esox_lucius
ENSG00000121486	TRMT1L	99	96.190	ENSFCAG00000011285	TRMT1L	100	93.605	Felis_catus
ENSG00000121486	TRMT1L	99	79.524	ENSFALG00000003177	TRMT1L	100	71.560	Ficedula_albicollis
ENSG00000121486	TRMT1L	99	98.095	ENSFDAG00000008822	TRMT1L	98	90.730	Fukomys_damarensis
ENSG00000121486	TRMT1L	99	71.905	ENSFHEG00000014328	trmt1l	99	63.284	Fundulus_heteroclitus
ENSG00000121486	TRMT1L	99	69.378	ENSGMOG00000009535	trmt1l	98	61.699	Gadus_morhua
ENSG00000121486	TRMT1L	99	79.524	ENSGALG00000033077	TRMT1L	85	72.068	Gallus_gallus
ENSG00000121486	TRMT1L	97	71.220	ENSGAFG00000012445	trmt1l	93	59.571	Gambusia_affinis
ENSG00000121486	TRMT1L	99	70.000	ENSGACG00000005050	trmt1l	98	62.480	Gasterosteus_aculeatus
ENSG00000121486	TRMT1L	99	84.286	ENSGAGG00000007441	TRMT1L	86	76.372	Gopherus_agassizii
ENSG00000121486	TRMT1L	100	99.045	ENSGGOG00000011778	TRMT1L	100	99.045	Gorilla_gorilla
ENSG00000121486	TRMT1L	99	70.952	ENSHBUG00000000622	trmt1l	98	62.687	Haplochromis_burtoni
ENSG00000121486	TRMT1L	99	97.619	ENSHGLG00000003135	-	97	87.201	Heterocephalus_glaber_female
ENSG00000121486	TRMT1L	100	82.949	ENSHGLG00000012595	-	99	78.138	Heterocephalus_glaber_female
ENSG00000121486	TRMT1L	99	97.619	ENSHGLG00100019412	-	98	92.405	Heterocephalus_glaber_male
ENSG00000121486	TRMT1L	100	82.949	ENSHGLG00100004569	-	99	78.138	Heterocephalus_glaber_male
ENSG00000121486	TRMT1L	95	74.129	ENSIPUG00000008873	trmt1l	97	61.783	Ictalurus_punctatus
ENSG00000121486	TRMT1L	99	98.571	ENSSTOG00000010332	TRMT1L	98	94.093	Ictidomys_tridecemlineatus
ENSG00000121486	TRMT1L	99	96.667	ENSJJAG00000010929	Trmt1l	100	84.803	Jaculus_jaculus
ENSG00000121486	TRMT1L	92	75.258	ENSKMAG00000010310	trmt1l	92	60.979	Kryptolebias_marmoratus
ENSG00000121486	TRMT1L	92	73.711	ENSLBEG00000003487	trmt1l	93	59.939	Labrus_bergylta
ENSG00000121486	TRMT1L	92	73.711	ENSLBEG00000007982	-	92	60.237	Labrus_bergylta
ENSG00000121486	TRMT1L	96	77.451	ENSLACG00000008447	TRMT1L	95	68.315	Latimeria_chalumnae
ENSG00000121486	TRMT1L	97	75.728	ENSLOCG00000001781	trmt1l	90	63.721	Lepisosteus_oculatus
ENSG00000121486	TRMT1L	99	98.571	ENSLAFG00000004339	TRMT1L	100	91.678	Loxodonta_africana
ENSG00000121486	TRMT1L	100	98.367	ENSMFAG00000037592	TRMT1L	100	98.367	Macaca_fascicularis
ENSG00000121486	TRMT1L	100	98.231	ENSMMUG00000013879	TRMT1L	100	98.231	Macaca_mulatta
ENSG00000121486	TRMT1L	100	98.503	ENSMNEG00000041637	TRMT1L	100	98.503	Macaca_nemestrina
ENSG00000121486	TRMT1L	100	98.367	ENSMLEG00000004840	TRMT1L	100	98.367	Mandrillus_leucophaeus
ENSG00000121486	TRMT1L	100	69.811	ENSMAMG00000015305	trmt1l	98	63.089	Mastacembelus_armatus
ENSG00000121486	TRMT1L	99	70.952	ENSMZEG00005017822	trmt1l	93	60.983	Maylandia_zebra
ENSG00000121486	TRMT1L	99	80.000	ENSMGAG00000000930	TRMT1L	99	71.057	Meleagris_gallopavo
ENSG00000121486	TRMT1L	99	84.651	ENSMAUG00000019870	Trmt1l	100	82.249	Mesocricetus_auratus
ENSG00000121486	TRMT1L	99	99.048	ENSMICG00000009494	TRMT1L	100	96.044	Microcebus_murinus
ENSG00000121486	TRMT1L	99	93.810	ENSMOCG00000016453	Trmt1l	100	86.221	Microtus_ochrogaster
ENSG00000121486	TRMT1L	99	69.048	ENSMMOG00000016961	trmt1l	97	60.737	Mola_mola
ENSG00000121486	TRMT1L	99	89.524	ENSMODG00000007454	TRMT1L	76	80.611	Monodelphis_domestica
ENSG00000121486	TRMT1L	99	70.476	ENSMALG00000019306	trmt1l	91	61.417	Monopterus_albus
ENSG00000121486	TRMT1L	99	96.667	MGP_CAROLIEiJ_G0014693	Trmt1l	100	87.585	Mus_caroli
ENSG00000121486	TRMT1L	99	96.667	ENSMUSG00000053286	Trmt1l	100	87.722	Mus_musculus
ENSG00000121486	TRMT1L	99	96.190	MGP_PahariEiJ_G0027929	Trmt1l	100	87.483	Mus_pahari
ENSG00000121486	TRMT1L	87	87.103	MGP_SPRETEiJ_G0015500	Trmt1l	100	87.103	Mus_spretus
ENSG00000121486	TRMT1L	100	88.965	ENSMPUG00000011859	TRMT1L	100	90.872	Mustela_putorius_furo
ENSG00000121486	TRMT1L	99	96.667	ENSMLUG00000001136	TRMT1L	100	91.132	Myotis_lucifugus
ENSG00000121486	TRMT1L	99	96.667	ENSNGAG00000011685	Trmt1l	98	88.252	Nannospalax_galili
ENSG00000121486	TRMT1L	95	69.802	ENSNBRG00000004053	trmt1l	93	65.101	Neolamprologus_brichardi
ENSG00000121486	TRMT1L	100	98.909	ENSNLEG00000018030	TRMT1L	100	98.909	Nomascus_leucogenys
ENSG00000121486	TRMT1L	60	96.094	ENSMEUG00000011344	TRMT1L	85	71.739	Notamacropus_eugenii
ENSG00000121486	TRMT1L	99	85.714	ENSOPRG00000000680	TRMT1L	99	77.029	Ochotona_princeps
ENSG00000121486	TRMT1L	99	98.095	ENSODEG00000000826	TRMT1L	97	86.076	Octodon_degus
ENSG00000121486	TRMT1L	99	70.476	ENSONIG00000007823	trmt1l	100	63.099	Oreochromis_niloticus
ENSG00000121486	TRMT1L	99	84.762	ENSOANG00000001010	TRMT1L	99	75.385	Ornithorhynchus_anatinus
ENSG00000121486	TRMT1L	99	91.429	ENSOCUG00000004896	TRMT1L	92	87.939	Oryctolagus_cuniculus
ENSG00000121486	TRMT1L	99	70.000	ENSORLG00000029610	trmt1l	98	63.097	Oryzias_latipes
ENSG00000121486	TRMT1L	99	70.000	ENSORLG00020002203	trmt1l	94	60.949	Oryzias_latipes_hni
ENSG00000121486	TRMT1L	99	70.000	ENSORLG00015021512	trmt1l	94	60.949	Oryzias_latipes_hsok
ENSG00000121486	TRMT1L	92	71.649	ENSOMEG00000016275	trmt1l	87	60.342	Oryzias_melastigma
ENSG00000121486	TRMT1L	99	78.199	ENSOGAG00000016186	TRMT1L	99	81.173	Otolemur_garnettii
ENSG00000121486	TRMT1L	99	98.095	ENSOARG00000003786	TRMT1L	100	90.946	Ovis_aries
ENSG00000121486	TRMT1L	100	99.591	ENSPPAG00000029141	TRMT1L	100	99.591	Pan_paniscus
ENSG00000121486	TRMT1L	99	96.190	ENSPPRG00000023981	TRMT1L	100	93.469	Panthera_pardus
ENSG00000121486	TRMT1L	99	96.190	ENSPTIG00000021754	TRMT1L	100	93.605	Panthera_tigris_altaica
ENSG00000121486	TRMT1L	100	99.591	ENSPTRG00000001776	TRMT1L	100	99.591	Pan_troglodytes
ENSG00000121486	TRMT1L	99	98.571	ENSPANG00000020890	TRMT1L	100	95.522	Papio_anubis
ENSG00000121486	TRMT1L	97	73.659	ENSPKIG00000005941	trmt1l	90	62.112	Paramormyrops_kingsleyae
ENSG00000121486	TRMT1L	100	82.547	ENSPSIG00000010011	TRMT1L	95	75.772	Pelodiscus_sinensis
ENSG00000121486	TRMT1L	92	61.929	ENSPMGG00000021359	trmt1l	95	58.590	Periophthalmus_magnuspinnatus
ENSG00000121486	TRMT1L	99	96.667	ENSPEMG00000000031	Trmt1l	100	86.630	Peromyscus_maniculatus_bairdii
ENSG00000121486	TRMT1L	99	62.963	ENSPMAG00000005838	trmt1l	100	58.121	Petromyzon_marinus
ENSG00000121486	TRMT1L	99	89.573	ENSPCIG00000002409	TRMT1L	87	80.335	Phascolarctos_cinereus
ENSG00000121486	TRMT1L	99	70.755	ENSPFOG00000003872	trmt1l	99	62.559	Poecilia_formosa
ENSG00000121486	TRMT1L	99	70.476	ENSPLAG00000010387	trmt1l	93	60.522	Poecilia_latipinna
ENSG00000121486	TRMT1L	99	70.476	ENSPMEG00000011828	trmt1l	99	62.623	Poecilia_mexicana
ENSG00000121486	TRMT1L	99	70.476	ENSPREG00000002866	trmt1l	93	60.522	Poecilia_reticulata
ENSG00000121486	TRMT1L	100	98.772	ENSPPYG00000000416	TRMT1L	100	98.772	Pongo_abelii
ENSG00000121486	TRMT1L	87	89.600	ENSPCAG00000008257	TRMT1L	89	89.600	Procavia_capensis
ENSG00000121486	TRMT1L	86	85.644	ENSPCOG00000005682	TRMT1L	93	85.644	Propithecus_coquereli
ENSG00000121486	TRMT1L	99	98.095	ENSPVAG00000005961	TRMT1L	100	83.401	Pteropus_vampyrus
ENSG00000121486	TRMT1L	99	70.000	ENSPNYG00000005607	trmt1l	98	62.852	Pundamilia_nyererei
ENSG00000121486	TRMT1L	99	72.381	ENSPNAG00000004389	trmt1l	88	62.934	Pygocentrus_nattereri
ENSG00000121486	TRMT1L	99	95.714	ENSRNOG00000002580	Trmt1l	100	86.903	Rattus_norvegicus
ENSG00000121486	TRMT1L	100	98.231	ENSRBIG00000042589	TRMT1L	100	98.231	Rhinopithecus_bieti
ENSG00000121486	TRMT1L	100	98.231	ENSRROG00000032183	TRMT1L	100	98.231	Rhinopithecus_roxellana
ENSG00000121486	TRMT1L	99	97.619	ENSSBOG00000029282	TRMT1L	100	95.907	Saimiri_boliviensis_boliviensis
ENSG00000121486	TRMT1L	99	75.120	ENSSFOG00015004878	trmt1l	91	63.003	Scleropages_formosus
ENSG00000121486	TRMT1L	56	71.429	ENSSMAG00000015425	trmt1l	90	71.429	Scophthalmus_maximus
ENSG00000121486	TRMT1L	99	70.952	ENSSDUG00000021807	trmt1l	99	63.339	Seriola_dumerili
ENSG00000121486	TRMT1L	99	70.000	ENSSLDG00000016579	trmt1l	99	63.175	Seriola_lalandi_dorsalis
ENSG00000121486	TRMT1L	99	91.905	ENSSARG00000010135	TRMT1L	87	83.257	Sorex_araneus
ENSG00000121486	TRMT1L	99	83.333	ENSSPUG00000003927	TRMT1L	99	76.568	Sphenodon_punctatus
ENSG00000121486	TRMT1L	99	72.249	ENSSPAG00000008597	trmt1l	93	61.290	Stegastes_partitus
ENSG00000121486	TRMT1L	95	96.517	ENSSSCG00000021393	TRMT1L	98	85.658	Sus_scrofa
ENSG00000121486	TRMT1L	99	79.048	ENSTGUG00000003737	TRMT1L	96	71.716	Taeniopygia_guttata
ENSG00000121486	TRMT1L	92	72.165	ENSTRUG00000002396	trmt1l	93	77.083	Takifugu_rubripes
ENSG00000121486	TRMT1L	99	66.190	ENSTNIG00000005534	trmt1l	99	64.319	Tetraodon_nigroviridis
ENSG00000121486	TRMT1L	86	88.119	ENSTBEG00000016498	TRMT1L	84	88.164	Tupaia_belangeri
ENSG00000121486	TRMT1L	99	98.571	ENSTTRG00000005892	TRMT1L	100	91.008	Tursiops_truncatus
ENSG00000121486	TRMT1L	99	98.571	ENSUAMG00000020936	TRMT1L	100	94.286	Ursus_americanus
ENSG00000121486	TRMT1L	99	98.571	ENSUMAG00000021919	TRMT1L	99	94.142	Ursus_maritimus
ENSG00000121486	TRMT1L	99	97.143	ENSVPAG00000011854	TRMT1L	100	93.884	Vicugna_pacos
ENSG00000121486	TRMT1L	99	98.571	ENSVVUG00000009166	TRMT1L	100	94.150	Vulpes_vulpes
ENSG00000121486	TRMT1L	98	69.231	ENSXETG00000004539	trmt1l	95	60.311	Xenopus_tropicalis
ENSG00000121486	TRMT1L	96	70.098	ENSXCOG00000007372	trmt1l	91	62.203	Xiphophorus_couchianus
ENSG00000121486	TRMT1L	99	70.000	ENSXMAG00000003575	trmt1l	98	62.355	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000049	tRNA binding	-	IEA	Function
GO:0002940	tRNA N2-guanine methylation	21873635.	IBA	Process
GO:0003723	RNA binding	22658674.	HDA	Function
GO:0004809	tRNA (guanine-N2-)-methyltransferase activity	21873635.	IBA	Function
GO:0005634	nucleus	21873635.	IBA	Component
GO:0007610	behavior	-	IEA	Process
GO:0046872	metal ion binding	-	IEA	Function