EuRBPDB

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  • Description
  • RBPome
  • Expression
  • Transcripts
  • Gene Model
  • Phenotypes
  • GWAS
  • PPI
  • Gene Ontology
Description
Ensembl ID
ENSG00000121892 (Gene tree)
Gene ID
23244
Gene Symbol
PDS5A
Alias
KIAA0648|PIG54|SCC-112
Full Name
PDS5 cohesin associated factor A
Gene Type
protein_coding
Species
Homo_sapiens
Status
putative
Strand
Minus strand
Length
155,094 bases
Position
chr4:39,822,863-39,977,956
Accession
29088
RBP type
non-canonical RBP
Summary
The protein encoded by this gene binds to the cohesin complex and associates with chromatin through most of the cell cycle. The encoded protein may play a role in regulating sister chromatid cohesion during mitosis. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2010]
RNA binding proteome (RBPome)
PIDTitleMethod TimeAuthorDoi
30607034Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)OOPS & HEK2932019 Jan 3Queiroz RMLDOI: 10.1038/s41587-018-0001-2
30528433The Human RNA-Binding Proteome and Its Dynamics during Translational ArrestXRNAX & HEK2932018 Dec 6Trendel JDOI: 10.1016/j.cell.2018.11.004
29431736Capturing the interactome of newly transcribed RNAPolyT-RICK & Hela2018 Feb 12Bao XDOI: 10.1038/nmeth.4595
29431736Capturing the interactome of newly transcribed RNARICK & Hela2018 Feb 12Bao XDOI: 10.1038/nmeth.4595
30528433The Human RNA-Binding Proteome and Its Dynamics during Translational ArrestXRNAX & Hela2018 Dec 6Trendel JDOI: 10.1016/j.cell.2018.11.004
30607034Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)OOPS & MCF10A2019 Jan 3Queiroz RMLDOI: 10.1038/s41587-018-0001-2
30607034Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)OOPS & U2OS2019 Jan 3Queiroz RMLDOI: 10.1038/s41587-018-0001-2
27453046Comprehensive Identification of RNA-Binding Domains in Human CellsRIC & Hela2016 Aug 18Castello ADOI: 10.1016/j.molcel.2016.06.029
Expression
Transcripts
Transcript IDNameLengthRefSeq ID Protein IDLengthRefSeq IDUniportKB ID
ENST00000503396PDS5A-2022685-ENSP00000426749600 (aa)-Q29RF7
ENST00000513798PDS5A-210494-ENSP00000424531165 (aa)-H0Y9L9
ENST00000303538PDS5A-2017176XM_011513672ENSP000003034271337 (aa)XP_011511974Q29RF7
ENST00000507020PDS5A-206781-ENSP00000424510126 (aa)-H0Y9L6
ENST00000508625PDS5A-208351--- (aa)--
ENST00000512643PDS5A-209581-ENSP0000042538643 (aa)-H0Y9X6
ENST00000503867PDS5A-204640--- (aa)--
ENST00000507766PDS5A-2074196--- (aa)--
ENST00000506262PDS5A-205559--- (aa)--
ENST00000503696PDS5A-203465--- (aa)--
Gene Model
Click here to download ENSG00000121892's gene model file
Phenotypes
ensgIDTraitpValuePubmed ID
ENSG00000121892Stroke4.3777531E-00419369658
ENSG00000121892Platelet Function Tests7.7900000E-006-
ENSG00000121892Platelet Function Tests4.7200000E-006-
ENSG00000121892Resistin6.0310000E-005-
ENSG00000121892Erythrocyte Count8.8940000E-009-
ENSG00000121892Erythrocyte Count7.5890000E-009-
ENSG00000121892Erythrocyte Count3.8630000E-009-
ENSG00000121892Erythrocyte Count3.1420000E-009-
GWAS
ensgIDSNPChromosomePositionSNP-risk TraitPubmedID95% CIOr or BEAT EFO ID
ENSG00000121892rs7671295439852592TSelf-reported math ability (MTAG)30038396[0.0065-0.0139] unit increase0.0102EFO_0004875
ENSG00000121892rs177529439839536THighest math class taken (MTAG)30038396[0.0077-0.0143] unit increase0.011EFO_0004875
ENSG00000121892rs7671295439852592TCognitive performance (MTAG)30038396[0.0092-0.0186] unit increase0.0139EFO_0008354
ENSG00000121892rs142278384439958606CRed cell distribution width28957414[0.017-0.034] unit increase0.0250597EFO_0005192
ENSG00000121892rs73229728439971570?Red cell distribution width30595370EFO_0005192
Protein-Protein Interaction (PPI)

Clik here to download ENSG00000121892's network

* RBP PPI network refers to all genes directly bind to RBP
Gene Ontology
Go IDGo_termPubmedIDEvidenceCategory
GO:0000775chromosome, centromeric region-TASComponent
GO:0000785chromatin21873635.IBAComponent
GO:0000785chromatin16682347.IDAComponent
GO:0005515protein binding15837422.15855230.17112726.17113138.17349791.19907496.21111234.26496610.IPIFunction
GO:0005634nucleus21873635.IBAComponent
GO:0005654nucleoplasm-IDAComponent
GO:0005654nucleoplasm-TASComponent
GO:0005694chromosome-TASComponent
GO:0005829cytosol-TASComponent
GO:0005886plasma membrane-IDAComponent
GO:0006281DNA repair21873635.IBAProcess
GO:0007064mitotic sister chromatid cohesion21873635.IBAProcess
GO:0007064mitotic sister chromatid cohesion21111234.IPIProcess
GO:0008156negative regulation of DNA replication19907496.IMPProcess
GO:0051301cell division-IEAProcess

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