EuRBPDB

Description

Ensembl ID: ENSG00000122692 (Gene tree)
Gene ID: 55234
Gene Symbol: SMU1
Alias: SMU-1|FLJ10805|BWD|fSAP57
Full Name: SMU1 DNA replication regulator and spliceosomal factor
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Minus strand
Length: 34,953 bases
Position: chr9:33,041,764-33,076,716
Accession: 18247
RBP type: non-canonical RBP
Summary: (SMU1 DNA Replication Regulator And Spliceosomal Factor) is a Protein Coding gene. Diseases associated with SMU1 include Influenza.

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
29431736	Capturing the interactome of newly transcribed RNA	PolyT-RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
11438655	Analysis of smu-1, a gene that regulates the alternative splicing of unc-52 pre-mRNA in Caenorhabditis elegans.	Mol Cell Biol	2001 Aug	Spike CA	-

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000397149	SMU1-201	7122	XM_005251503	ENSP00000380336	513 (aa)	XP_005251560	Q2TAY7

Gene Model

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000122692	Pancreatic Neoplasms	1.4480000E-004	19648918
ENSG00000122692	Platelet Function Tests	1.3100000E-006	-
ENSG00000122692	Platelet Function Tests	3.2000000E-007	-

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000122692	rs7041702	9	33053432	A	Educational attainment (MTAG)	30038396	[0.0075-0.0133] unit decrease	0.0104	EFO_0004784
ENSG00000122692	rs11789823	9	33056301	?	Adolescent idiopathic scoliosis	30019117			EFO_0005423
ENSG00000122692	rs7041702	9	33053432	A	Educational attainment (years of education)	30038396	[0.008-0.0142] unit decrease	0.0111	EFO_0004784

Protein-Protein Interaction (PPI)

* RBP PPI network refers to all genes directly bind to RBP

Orthologs identified by RBPome

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000122692	SMU1	100	100.000	ENSMUSG00000028409	Smu1	100	100.000	Mus_musculus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000381	regulation of alternative mRNA splicing, via spliceosome	-	ISS	Process
GO:0000398	mRNA splicing, via spliceosome	28781166.	IDA	Process
GO:0005515	protein binding	21516116.22365833.25416956.	IPI	Function
GO:0005634	nucleus	21873635.	IBA	Component
GO:0005634	nucleus	28781166.	IDA	Component
GO:0005737	cytoplasm	-	IEA	Component
GO:0008380	RNA splicing	21873635.	IBA	Process
GO:0016607	nuclear speck	-	ISS	Component
GO:0071005	U2-type precatalytic spliceosome	28781166.	IDA	Component