EuRBPDB

Basic Information
Cancer Related Information

Description

RBPome

Expression

Transcripts

Gene Model

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000122966 (Gene tree)
Gene ID: 11113
Gene Symbol: CIT
Alias: KIAA0949|STK21|CRIK|CITK
Full Name: citron rho-interacting serine/threonine kinase
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Minus strand
Length: 191,529 bases
Position: chr12:119,685,790-119,877,318
Accession: 1985
RBP type: non-canonical RBP
Summary: This gene encodes a serine/threonine-protein kinase that functions in cell division. Together with the kinesin KIF14, this protein localizes to the central spindle and midbody, and functions to promote efficient cytokinesis. This protein is involved in central nervous system development. Polymorphisms in this gene are associated with bipolar disorder and risk for schizophrenia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011]

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000469414	CIT-204	441	-	-	- (aa)	-	-
ENST00000545913	CIT-217	8520	-	-	- (aa)	-	-
ENST00000392521	CIT-203	8708	XM_006719206	ENSP00000376306	2069 (aa)	XP_006719269	O14578
ENST00000261833	CIT-201	8578	XM_011537787	ENSP00000261833	2027 (aa)	XP_011536089	O14578
ENST00000539413	CIT-210	554	-	-	- (aa)	-	-
ENST00000544588	CIT-214	594	-	-	- (aa)	-	-
ENST00000543239	CIT-212	586	-	-	- (aa)	-	-
ENST00000544800	CIT-215	564	-	-	- (aa)	-	-
ENST00000546026	CIT-218	677	-	ENSP00000446105	162 (aa)	-	F5H4K4
ENST00000538073	CIT-209	533	-	-	- (aa)	-	-
ENST00000537607	CIT-208	4958	-	-	- (aa)	-	-
ENST00000536008	CIT-206	567	-	-	- (aa)	-	-
ENST00000541841	CIT-211	590	-	-	- (aa)	-	-
ENST00000536325	CIT-207	329	-	ENSP00000443199	109 (aa)	-	H0YGG8
ENST00000543324	CIT-213	497	-	-	- (aa)	-	-
ENST00000392520	CIT-202	5205	XM_011537789	ENSP00000376305	1640 (aa)	XP_011536091	H7BYJ3
ENST00000612548	CIT-219	1799	-	ENSP00000482318	482 (aa)	-	O14578
ENST00000488203	CIT-205	2283	-	-	- (aa)	-	-
ENST00000544872	CIT-216	524	-	-	- (aa)	-	-

Gene Model

Click here to download ENSG00000122966's gene model file

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000122966	Child Development Disorders, Pervasive	5.2311000E-006	-
ENSG00000122966	Inflammatory Bowel Diseases	6E-8	26192919
ENSG00000122966	Colitis, Ulcerative	2E-7	26192919
ENSG00000122966	Urinary Incontinence	9E-7	25524241

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000122966	rs4767841	12	119724394	?	Urgency urinary incontinence	25524241	[1.00-1.42]	1.19	EFO_0006865
ENSG00000122966	rs11064881	12	119709120	A	Ulcerative colitis	26192919	[1.08-1.17]	1.1273501	EFO_0000729
ENSG00000122966	rs11064881	12	119709120	A	Inflammatory bowel disease	26192919	[1.07-1.14]	1.1044849	EFO_0003767
ENSG00000122966	rs203351	12	119794842	?	Adolescent idiopathic scoliosis	30019117			EFO_0005423
ENSG00000122966	rs278142	12	119762308	?	Adolescent idiopathic scoliosis	30019117			EFO_0005423
ENSG00000122966	rs804667	12	119712391	T	Number of sexual partners	30643258	[0.01-0.021] unit decrease	0.015519196	EFO_0007877
ENSG00000122966	rs17442937	12	119832834	?	Red cell distribution width	30595370			EFO_0005192
ENSG00000122966	rs11064881	12	119709120	?	White blood cell count	30595370			EFO_0004308

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000122966's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs identified by RBPome

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000122966	CIT	90	41.950	ENSG00000198752	CDC42BPB	86	55.856	Homo_sapiens
ENSG00000122966	CIT	90	40.136	ENSG00000143776	CDC42BPA	73	32.820	Homo_sapiens
ENSG00000122966	CIT	90	40.455	ENSG00000134318	ROCK2	99	42.424	Homo_sapiens
ENSG00000122966	CIT	83	43.956	ENSG00000067900	ROCK1	69	32.371	Homo_sapiens

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000086	G2/M transition of mitotic cell cycle	-	IEA	Process
GO:0000278	mitotic cell cycle	11086988.	ISS	Process
GO:0000281	mitotic cytokinesis	16236794.27453578.	IMP	Process
GO:0001889	liver development	-	IEA	Process
GO:0004674	protein serine/threonine kinase activity	9792683.	ISS	Function
GO:0005515	protein binding	16431929.	IPI	Function
GO:0005524	ATP binding	-	IEA	Function
GO:0005634	nucleus	-	IEA	Component
GO:0005829	cytosol	-	TAS	Component
GO:0006468	protein phosphorylation	-	IEA	Process
GO:0007030	Golgi organization	-	IEA	Process
GO:0008064	regulation of actin polymerization or depolymerization	-	IEA	Process
GO:0016020	membrane	19946888.	HDA	Component
GO:0017124	SH3 domain binding	-	IEA	Function
GO:0030165	PDZ domain binding	17474715.	IDA	Function
GO:0030496	midbody	-	IEA	Component
GO:0031985	Golgi cisterna	-	IEA	Component
GO:0032154	cleavage furrow	-	IEA	Component
GO:0032467	positive regulation of cytokinesis	16431929.	IMP	Process
GO:0035556	intracellular signal transduction	-	IEA	Process
GO:0043025	neuronal cell body	-	IEA	Component
GO:0046872	metal ion binding	-	IEA	Function
GO:0048699	generation of neurons	11086988.	ISS	Process
GO:0051402	neuron apoptotic process	27453578.	IMP	Process
GO:0097110	scaffold protein binding	17474715.	IDA	Function

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
22761715	Identification of kinases regulating prostate cancer cell growth using an RNAi phenotypic screen.	PLoS One	2012	Whitworth H	doi: 10.1371/journal.pone.0038950

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq
BLCA	chr12	119721398	Silent	NA	L1173L	0.15
BLCA	chr12	119701901	Missense_Mutation	novel	I1746V	0.33
BLCA	chr12	119712657	Missense_Mutation	novel	P1498S	0.46
BLCA	chr12	119720540	Missense_Mutation	novel	Q1218E	0.14
BLCA	chr12	119776778	Missense_Mutation	NA	S577L	0.67
BLCA	chr12	119850271	Missense_Mutation	NA	S140L	0.28
BLCA	chr12	119712615	Missense_Mutation	NA	E1512K	0.48
BLCA	chr12	119728568	Missense_Mutation	NA	M1133I	0.24
BLCA	chr12	119825351	Silent	rs760427459	P257P	0.37
BLCA	chr12	119701739	Missense_Mutation	novel	K1767N	0.29
BLCA	chr12	119869162	Missense_Mutation	novel	L46I	0.22
BLCA	chr12	119822916	Missense_Mutation	novel	Q339E	0.12
BLCA	chr12	119832781	Missense_Mutation	novel	S248L	0.19
BLCA	chr12	119825168	Missense_Mutation	novel	F318L	0.17
BLCA	chr12	119775809	Missense_Mutation	novel	E640Q	0.09
BLCA	chr12	119782568	Missense_Mutation	NA	L539F	0.07
BLCA	chr12	119825259	Missense_Mutation	novel	S288L	0.32
BLCA	chr12	119783974	Silent	NA	L493L	0.19
BLCA	chr12	119757395	Silent	NA	L852L	0.37
BLCA	chr12	119697758	Missense_Mutation	rs776383369	A1886V	0.07
BLCA	chr12	119704433	Missense_Mutation	novel	C1703S	0.24
BLCA	chr12	119752115	Missense_Mutation	rs747447396	R905C	0.4
BLCA	chr12	119785001	Missense_Mutation	novel	K454E	0.37
BLCA	chr12	119735306	Missense_Mutation	NA	E962K	0.09
BLCA	chr12	119708313	Missense_Mutation	novel	E1651Q	0.12
BLCA	chr12	119770858	Intron	rs762975110		0.27
BLCA	chr12	119767123	Silent	novel	L714L	0.18
BLCA	chr12	119850201	Silent	novel	A163A	0.47
BLCA	chr12	119850202	Missense_Mutation	novel	A163D	0.47
BRCA	chr12	119708258	Missense_Mutation	NA	S1669F	0.47
BRCA	chr12	119718283	Missense_Mutation	rs779515686	P1335L	0.24
BRCA	chr12	119728523	Silent	NA	L1148L	0.18
BRCA	chr12	119850185	Missense_Mutation	NA	H169N	0.38
BRCA	chr12	119687591	3'UTR	novel		0.17
BRCA	chr12	119712314	Missense_Mutation	novel	P1531L	0.05
BRCA	chr12	119752115	Missense_Mutation	rs747447396	R905C	0.35
BRCA	chr12	119712609	Missense_Mutation	NA	A1514S	0.23
BRCA	chr12	119834108	Missense_Mutation	novel	H213Y	0.14
BRCA	chr12	119784918	Intron	novel		0.3
BRCA	chr12	119857646	Silent	NA	F97F	0.19
BRCA	chr12	119718848	Missense_Mutation	novel	R1243Q	0.37
BRCA	chr12	119714310	Missense_Mutation	rs774914678	R1356H	0.18
BRCA	chr12	119718302	Missense_Mutation	NA	A1329T	0.46
BRCA	chr12	119857601	Missense_Mutation	rs374311938	Q112H	0.32
BRCA	chr12	119713673	Intron	NA		0.23
BRCA	chr12	119752115	Missense_Mutation	rs747447396	R905C	0.19
BRCA	chr12	119857695	Missense_Mutation	novel	S81F	0.07
BRCA	chr12	119775796	Missense_Mutation	novel	K644R	0.05
BRCA	chr12	119713615	Missense_Mutation	novel	T1405K	0.15
BRCA	chr12	119700778	Missense_Mutation	rs368981957	D1822N	0.1
BRCA	chr12	119776737	Missense_Mutation	NA	E591K	0.26
BRCA	chr12	119690434	Missense_Mutation	NA	P1926L	0.3
BRCA	chr12	119701688	Silent	rs773246397	F1784F	0.22
BRCA	chr12	119687494	3'UTR	novel		0.16
BRCA	chr12	119735219	Missense_Mutation	NA	V991L	0.21
BRCA	chr12	119714310	Missense_Mutation	rs774914678	R1356H	0.19
CESC	chr12	119704391	Missense_Mutation	NA	E1717A	0.38
CESC	chr12	119735268	Silent	rs150564429	L974L	0.3
CESC	chr12	119721380	Missense_Mutation	NA	E1179K	0.25
CESC	chr12	119752172	Frame_Shift_Del	novel	*R886Afs5**	0.14
CESC	chr12	119803381	Missense_Mutation	novel	P374S	0.06
CESC	chr12	119687681	3'UTR	novel		0.3
CESC	chr12	119718390	Silent	novel	T1299T	0.43
CESC	chr12	119718837	Missense_Mutation	novel	D1247N	0.56
CESC	chr12	119734243	Missense_Mutation	rs200184645	V1049I	0.21
CESC	chr12	119876144	Missense_Mutation	rs766425863	R9W	0.21
CESC	chr12	119685980	3'UTR	novel		0.35
CESC	chr12	119687439	3'UTR	novel		0.24
CESC	chr12	119686290	3'UTR	novel		0.38
CESC	chr12	119690359	Missense_Mutation	rs371376893	R1951Q	0.31
CESC	chr12	119697785	Missense_Mutation	novel	A1877D	0.1
CESC	chr12	119686270	3'UTR	novel		0.36
CESC	chr12	119772780	Missense_Mutation	novel	V691A	0.31
CESC	chr12	119825209	Missense_Mutation	NA	E305K	0.33
CESC	chr12	119685848	3'UTR	novel		0.5
CESC	chr12	119822965	Missense_Mutation	NA	L322F	0.21
CESC	chr12	119686641	3'UTR	novel		0.3
COAD	chr12	119735206	Missense_Mutation	NA	R995H	0.35
COAD	chr12	119752133	Missense_Mutation	NA	A899T	0.31
COAD	chr12	119688000	3'UTR	novel		0.15
COAD	chr12	119758694	Missense_Mutation	novel	N768H	0.05
COAD	chr12	119784222	Intron	novel		0.31
COAD	chr12	119822826	Missense_Mutation	rs754496604	R369C	0.19
COAD	chr12	119857693	Missense_Mutation	rs745580393	D82N	0.08
COAD	chr12	119735307	Silent	rs149750500	A961A	0.36
COAD	chr12	119752133	Missense_Mutation	NA	A899T	0.27
COAD	chr12	119734356	Missense_Mutation	novel	T1011M	0.15
COAD	chr12	119784267	Intron	novel		0.08
COAD	chr12	119735189	Nonsense_Mutation	NA	R1001*	0.16
COAD	chr12	119825318	Silent	rs137928558	V268V	0.46
COAD	chr12	119701944	Silent	NA	S1731S	0.18
COAD	chr12	119712615	Missense_Mutation	NA	E1512K	0.3
COAD	chr12	119735325	Silent	novel	Q955Q	0.05
COAD	chr12	119850274	Missense_Mutation	novel	V139G	0.2
COAD	chr12	119697988	Missense_Mutation	rs763157071	R1855H	0.38
COAD	chr12	119752114	Missense_Mutation	novel	R905H	0.52
COAD	chr12	119718405	Silent	novel	A1294A	0.42
COAD	chr12	119730621	Silent	rs138923592	A1078A	0.49
COAD	chr12	119772864	Missense_Mutation	NA	R663H	0.27
COAD	chr12	119697757	Silent	NA	A1886A	0.16
COAD	chr12	119784046	Silent	rs780631864	E469E	0.22
COAD	chr12	119714310	Missense_Mutation	novel	R1356L	0.05
COAD	chr12	119735246	Missense_Mutation	novel	D982N	0.06
COAD	chr12	119713594	Missense_Mutation	NA	G1412D	0.47
COAD	chr12	119721343	Missense_Mutation	novel	R1191I	0.07
COAD	chr12	119757480	Missense_Mutation	NA	G824E	0.1
COAD	chr12	119850238	Missense_Mutation	rs61735296	R151Q	0.12
COAD	chr12	119697808	Silent	rs367573015	P1869P	0.48
COAD	chr12	119730581	Missense_Mutation	NA	A1092T	0.29
COAD	chr12	119770858	Intron	rs762975110		0.32
COAD	chr12	119775801	Missense_Mutation	rs754514332	Q642H	0.42
COAD	chr12	119782562	Missense_Mutation	NA	D541Y	0.3
COAD	chr12	119822913	Missense_Mutation	NA	S340R	0.32
COAD	chr12	119730573	Silent	novel	K1094K	0.45
COAD	chr12	119734208	Silent	rs768920012	R1060R	0.33
COAD	chr12	119734204	Nonsense_Mutation	NA	R1062*	0.24
COAD	chr12	119784197	Intron	novel		0.25
COAD	chr12	119770903	Intron	NA		0.15
COAD	chr12	119850253	Missense_Mutation	rs757874504	R146Q	0.37
COAD	chr12	119730599	Missense_Mutation	NA	R1086C	0.33
COAD	chr12	119776700	Missense_Mutation	rs141341431	A603V	0.22
DLBC	chr12	119857632	Missense_Mutation	novel	L102P	0.31
ESCA	chr12	119687296	3'UTR	novel		0.26
ESCA	chr12	119690440	Missense_Mutation	novel	R1924L	0.15
ESCA	chr12	119690172	Silent	novel	T2013T	0.4
ESCA	chr12	119690359	Missense_Mutation	rs371376893	R1951Q	0.19
ESCA	chr12	119784215	Intron	novel		0.41
GBM	chr12	119752055	Missense_Mutation	novel	L925F	0.11
GBM	chr12	119857552	Nonsense_Mutation	novel	K129*	0.04
GBM	chr12	119710375	Silent	NA	V1607V	0.12
GBM	chr12	119770884	Intron	novel		0.06
GBM	chr12	119834099	Missense_Mutation	novel	G216R	0.1
GBM	chr12	119688109	3'UTR	novel		0.1
GBM	chr12	119721333	Missense_Mutation	novel	L1194F	0.13
GBM	chr12	119825177	Missense_Mutation	novel	I315M	0.15
GBM	chr12	119776370	Silent	rs35132196	A625A	0.39
GBM	chr12	119832774	Missense_Mutation	novel	K250N	0.39
GBM	chr12	119704393	Silent	rs780981739	N1716N	0.41
GBM	chr12	119761038	Silent	novel	I732I	0.07
GBM	chr12	119832782	Missense_Mutation	novel	S248T	0.06
GBM	chr12	119697684	Missense_Mutation	novel	H1911Y	0.07
GBM	chr12	119700820	Missense_Mutation	NA	G1808R	0.28
GBM	chr12	119700826	Splice_Site	novel	X1806_splice	0.14
GBM	chr12	119713271	Missense_Mutation	novel	G1462D	0.47
GBM	chr12	119775798	Missense_Mutation	novel	E643D	0.32
GBM	chr12	119690182	Missense_Mutation	novel	A2010V	0.38
HNSC	chr12	119690440	Missense_Mutation	novel	R1924Q	0.16
HNSC	chr12	119690364	Missense_Mutation	novel	H1949Q	0.26
HNSC	chr12	119803281	Missense_Mutation	novel	S407L	0.28
HNSC	chr12	119697719	Missense_Mutation	novel	K1899M	0.23
HNSC	chr12	119767093	Missense_Mutation	novel	K724N	0.17
HNSC	chr12	119783927	Missense_Mutation	novel	T509S	0.04
HNSC	chr12	119728604	Splice_Region	novel	L1121L	0.05
HNSC	chr12	119701667	Silent	novel	V1791V	0.24
HNSC	chr12	119710578	Missense_Mutation	novel	R1591S	0.3
HNSC	chr12	119730587	Nonsense_Mutation	NA	E1090*	0.12
HNSC	chr12	119735203	Missense_Mutation	novel	R996L	0.27
HNSC	chr12	119825175	In_Frame_Del	rs758752899	I315del	0.18
HNSC	chr12	119735172	Silent	novel	T1006T	0.15
HNSC	chr12	119776766	Missense_Mutation	rs201303983	R581Q	0.34
HNSC	chr12	119757515	Silent	novel	L812L	0.15
HNSC	chr12	119785060	Missense_Mutation	novel	V434A	0.14
HNSC	chr12	119690235	Silent	novel	R1992R	0.29
HNSC	chr12	119734267	Missense_Mutation	rs770757019	R1041W	0.46
KICH	chr12	119712288	Missense_Mutation	novel	T1540A	0.3
KIRC	chr12	119735310	Missense_Mutation	NA	N960K	0.31
KIRC	chr12	119758669	Missense_Mutation	NA	S776F	0.22
KIRC	chr12	119761014	Silent	novel	E740E	0.04
KIRC	chr12	119690370	Silent	NA	P1947P	0.25
KIRP	chr12	119735348	Missense_Mutation	NA	D948N	0.39
KIRP	chr12	119720479	Missense_Mutation	NA	K1238R	0.53
LAML	chr12	119776843	Splice_Site	novel	X556_splice	0.08
LAML	chr12	119697811	Silent	novel	I1868I	0.05
LAML	chr12	119776408	Missense_Mutation	NA	A613T	0.03
LAML	chr12	119772864	Missense_Mutation	NA	R663H	0.06
LGG	chr12	119713260	Missense_Mutation	novel	K1466E	0.44
LGG	chr12	119713646	Splice_Site	novel	X1394_splice	0.15
LGG	chr12	119690385	Silent	NA	A1942A	0.36
LGG	chr12	119752135	Missense_Mutation	rs748498978	A898V	0.34
LGG	chr12	119735309	Missense_Mutation	rs543172777	A961T	0.33
LGG	chr12	119714217	Missense_Mutation	rs140614337	R1387H	0.47
LIHC	chr12	119713595	Missense_Mutation	rs370080702	G1412S	0.38
LIHC	chr12	119784401	Intron	novel		0.75
LIHC	chr12	119775837	Missense_Mutation	novel	I630M	0.31
LIHC	chr12	119834129	Missense_Mutation	novel	I206V	0.34
LIHC	chr12	119688224	3'UTR	novel		0.05
LIHC	chr12	119803216	Missense_Mutation	NA	G429R	0.7
LIHC	chr12	119782604	Missense_Mutation	novel	E527K	0.55
LIHC	chr12	119785039	Missense_Mutation	NA	P441H	0.05
LIHC	chr12	119834121	Silent	NA	A208A	0.38
LIHC	chr12	119735193	Silent	NA	T999T	0.34
LIHC	chr12	119784268	Intron	novel		0.4
LUAD	chr12	119734176	Missense_Mutation	NA	E1071V	0.68
LUAD	chr12	119832792	Silent	rs747648400	A244A	0.1
LUAD	chr12	119728510	Silent	novel	L1153L	0.32
LUAD	chr12	119708308	Silent	novel	R1652R	0.18
LUAD	chr12	119783979	Nonsense_Mutation	novel	E492*	0.11
LUAD	chr12	119690342	Missense_Mutation	NA	H1957Y	0.29
LUAD	chr12	119690290	Missense_Mutation	NA	R1974H	0.09
LUAD	chr12	119714197	Nonsense_Mutation	novel	E1394*	0.25
LUAD	chr12	119850260	Nonsense_Mutation	NA	E144*	0.09
LUAD	chr12	119690311	Missense_Mutation	NA	R1967L	0.11
LUAD	chr12	119718286	Missense_Mutation	novel	A1334V	0.38
LUAD	chr12	119770848	Intron	novel		0.44
LUAD	chr12	119776802	Missense_Mutation	novel	N569I	0.38
LUAD	chr12	119825281	Missense_Mutation	NA	G281C	0.43
LUAD	chr12	119776374	Missense_Mutation	NA	Y624F	0.2
LUAD	chr12	119698017	Silent	NA	N1845N	0.04
LUAD	chr12	119697757	Silent	NA	A1886A	0.24
LUAD	chr12	119704396	Silent	NA	Y1715Y	0.12
LUAD	chr12	119776698	Missense_Mutation	novel	T604P	0.19
LUAD	chr12	119784023	Missense_Mutation	NA	R477L	0.25
LUAD	chr12	119772832	Missense_Mutation	novel	E674K	0.25
LUAD	chr12	119770787	Intron	novel		0.15
LUAD	chr12	119697802	Silent	NA	P1871P	0.14
LUAD	chr12	119721358	Missense_Mutation	NA	L1186P	0.19
LUAD	chr12	119857591	Nonsense_Mutation	NA	E116*	0.26
LUSC	chr12	119761020	Silent	novel	D738D	0.28
LUSC	chr12	119701902	Silent	NA	L1745L	0.26
LUSC	chr12	119721367	Missense_Mutation	novel	R1183L	0.33
LUSC	chr12	119718715	Silent	novel	R1287R	0.19
LUSC	chr12	119718716	Missense_Mutation	novel	R1287P	0.19
LUSC	chr12	119775824	Missense_Mutation	novel	Q635E	0.28
LUSC	chr12	119767101	Nonsense_Mutation	novel	E722*	0.28
LUSC	chr12	119701675	Missense_Mutation	novel	V1789L	0.12
LUSC	chr12	119784923	Intron	novel		0.6
LUSC	chr12	119697776	Nonsense_Mutation	NA	S1880*	0.36
LUSC	chr12	119713478	Missense_Mutation	novel	K1451E	0.38
LUSC	chr12	119772872	Missense_Mutation	rs753261617	Q660H	0.38
LUSC	chr12	119711068	Intron	novel		0.17
LUSC	chr12	119784324	Intron	novel		0.12
LUSC	chr12	119785028	Missense_Mutation	novel	S445C	0.34
LUSC	chr12	119688189	3'UTR	novel		0.57
LUSC	chr12	119850217	Missense_Mutation	NA	P158L	0.48
LUSC	chr12	119857638	Missense_Mutation	novel	R100K	0.28
LUSC	chr12	119770817	Intron	novel		0.12
LUSC	chr12	119688238	Silent	novel	S2026S	0.21
LUSC	chr12	119734329	Missense_Mutation	NA	T1020S	0.22
LUSC	chr12	119712639	Missense_Mutation	novel	I1504V	0.42
LUSC	chr12	119757522	Missense_Mutation	NA	S810C	0.14
LUSC	chr12	119767108	Missense_Mutation	novel	Q719H	0.35
LUSC	chr12	119690332	Missense_Mutation	novel	R1960L	0.33
MESO	chr12	119690247	Silent	rs772283770	T1988T	0.69
OV	chr12	119697802	Silent	rs373669183	P1871P	0.25
OV	chr12	119876163	Silent	NA	L2L	0.29
OV	chr12	119713595	Missense_Mutation	rs370080702	G1412S	0.33
OV	chr12	119701926	Missense_Mutation	NA	I1737M	0.36
OV	chr12	119876139	Frame_Shift_Ins	novel	*P11Sfs8**	0.05
OV	chr12	119761040	Missense_Mutation	NA	I732V	0.06
OV	chr12	119757402	Missense_Mutation	rs747310422	R850Q	0.43
OV	chr12	119697696	Missense_Mutation	rs367930288	G1907S	0.37
OV	chr12	119772857	Silent	NA	A665A	0.16
OV	chr12	119776741	Silent	novel	L589L	0.24
OV	chr12	119770858	Intron	rs762975110		0.39
OV	chr12	119708266	Silent	novel	L1666L	0.04
OV	chr12	119767107	Missense_Mutation	novel	H720N	0.05
OV	chr12	119742453	Missense_Mutation	novel	D930E	0.83
OV	chr12	119688160	3'UTR	novel		0.2
OV	chr12	119876140	Missense_Mutation	novel	N10I	0.06
PAAD	chr12	119697992	Missense_Mutation	novel	A1854T	0.08
PAAD	chr12	119701933	Missense_Mutation	novel	S1735N	0.23
PAAD	chr12	119730551	Missense_Mutation	rs146605071	A1102T	0.21
PCPG	chr12	119784922	Intron	novel		0.59
PRAD	chr12	119776732	Silent	novel	S592S	0.08
PRAD	chr12	119752115	Missense_Mutation	rs747447396	R905C	0.29
READ	chr12	119721441	Missense_Mutation	NA	K1158N	0.34
READ	chr12	119772883	Missense_Mutation	rs778060632	E657K	0.46
READ	chr12	119752059	Silent	novel	Q923Q	0.1
READ	chr12	119735267	Missense_Mutation	novel	D975N	0.4
READ	chr12	119713206	Nonsense_Mutation	NA	E1484*	0.44
READ	chr12	119776772	Missense_Mutation	NA	R579I	0.38
READ	chr12	119803280	Silent	novel	S407S	0.15
SARC	chr12	119784917	Intron	novel		0.56
SARC	chr12	119734243	Missense_Mutation	rs200184645	V1049I	0.13
SARC	chr12	119770902	Intron	novel		0.09
SARC	chr12	119710331	Missense_Mutation	novel	S1622F	0.38
SKCM	chr12	119760952	Missense_Mutation	novel	S761N	0.35
SKCM	chr12	119697985	Missense_Mutation	NA	S1856F	0.27
SKCM	chr12	119718845	Missense_Mutation	rs750567021	R1244Q	0.09
SKCM	chr12	119869058	Splice_Site	NA	X80_splice	0.3
SKCM	chr12	119758669	Missense_Mutation	NA	S776F	0.25
SKCM	chr12	119688197	3'UTR	novel		0.32
SKCM	chr12	119710369	Silent	novel	T1609T	0.45
SKCM	chr12	119710370	Missense_Mutation	novel	T1609I	0.45
SKCM	chr12	119783951	Missense_Mutation	NA	S501F	0.36
SKCM	chr12	119850219	Silent	NA	I157I	0.38
SKCM	chr12	119850185	Missense_Mutation	novel	H169Y	0.16
SKCM	chr12	119785014	Silent	novel	K449K	0.25
SKCM	chr12	119713281	Missense_Mutation	NA	G1459R	0.51
SKCM	chr12	119718845	Missense_Mutation	rs750567021	R1244Q	0.64
SKCM	chr12	119803317	Missense_Mutation	rs752750796	S395L	0.19
SKCM	chr12	119735205	Silent	NA	R995R	0.35
SKCM	chr12	119785024	Missense_Mutation	NA	S446F	0.33
SKCM	chr12	119742425	Missense_Mutation	novel	R940C	0.36
SKCM	chr12	119876157	Silent	novel	F4F	0.39
SKCM	chr12	119697663	Missense_Mutation	rs201262799	R1918C	0.18
SKCM	chr12	119700756	Missense_Mutation	NA	P1829L	0.1
SKCM	chr12	119710350	Silent	NA	L1616L	0.39
SKCM	chr12	119712610	Silent	rs147828404	L1513L	0.16
SKCM	chr12	119734279	Silent	NA	L1037L	0.25
SKCM	chr12	119803317	Missense_Mutation	rs752750796	S395L	0.32
SKCM	chr12	119825217	Missense_Mutation	NA	P302L	0.32
SKCM	chr12	119784892	Intron	novel		0.25
SKCM	chr12	119782600	Missense_Mutation	NA	V528G	0.22
SKCM	chr12	119718770	Missense_Mutation	NA	K1269T	0.34
SKCM	chr12	119728521	Missense_Mutation	NA	K1149T	0.45
SKCM	chr12	119711077	Intron	novel		0.19
SKCM	chr12	119757418	Missense_Mutation	rs762575363	H845Y	0.17
SKCM	chr12	119757419	Silent	novel	D844D	0.17
SKCM	chr12	119690229	Silent	rs563991002	P1994P	0.5
SKCM	chr12	119690230	Missense_Mutation	novel	P1994L	0.5
SKCM	chr12	119803299	Missense_Mutation	rs767424020	P401L	0.56
SKCM	chr12	119752182	Silent	novel	S882S	0.36
SKCM	chr12	119701857	Silent	rs771848800	T1760T	0.24
SKCM	chr12	119822899	Silent	NA	G344G	0.24
SKCM	chr12	119713272	Missense_Mutation	NA	G1462S	0.23
SKCM	chr12	119718765	Missense_Mutation	novel	R1271C	0.15
SKCM	chr12	119718357	Silent	rs140364771	A1310A	0.17
SKCM	chr12	119721401	Missense_Mutation	NA	R1172C	0.32
SKCM	chr12	119767143	Nonsense_Mutation	NA	Q708*	0.34
SKCM	chr12	119701748	Silent	NA	F1764F	0.32
SKCM	chr12	119728604	Splice_Region	NA	L1121L	0.57
SKCM	chr12	119783951	Missense_Mutation	NA	S501F	0.18
SKCM	chr12	119850219	Silent	NA	I157I	0.24
SKCM	chr12	119784910	Intron	novel		0.25
SKCM	chr12	119730599	Missense_Mutation	NA	R1086C	0.11
SKCM	chr12	119803304	Silent	NA	S399S	0.4
SKCM	chr12	119712675	Missense_Mutation	NA	E1492K	0.51
SKCM	chr12	119803376	Silent	rs200757503	F375F	0.1
SKCM	chr12	119712684	Missense_Mutation	NA	P1489S	0.54
SKCM	chr12	119803337	Silent	NA	F388F	0.1
SKCM	chr12	119758695	Silent	rs747238115	I767I	0.17
SKCM	chr12	119784283	Intron	novel		0.21
STAD	chr12	119718741	Missense_Mutation	novel	L1279I	0.4
STAD	chr12	119772836	Silent	NA	E672E	0.19
STAD	chr12	119752202	Missense_Mutation	NA	L876V	0.14
STAD	chr12	119708290	Silent	rs377318034	D1658D	0.14
STAD	chr12	119770904	Intron	rs753293581		0.13
STAD	chr12	119712182	Missense_Mutation	novel	D1575G	0.44
STAD	chr12	119770903	Intron	NA		0.27
STAD	chr12	119728508	Silent	NA	L1153L	0.28
STAD	chr12	119712696	Splice_Site	NA	X1485_splice	0.22
STAD	chr12	119712294	Missense_Mutation	rs774673206	G1538R	0.48
STAD	chr12	119697682	Silent	NA	H1911H	0.3
STAD	chr12	119734196	Silent	rs747244776	L1064L	0.29
STAD	chr12	119782558	Missense_Mutation	NA	I542T	0.25
STAD	chr12	119876170	5'UTR	novel		0.17
STAD	chr12	119690227	In_Frame_Del	novel	M1985_R1996del	0.26
STAD	chr12	119767176	Missense_Mutation	rs746443265	E697K	0.32
STAD	chr12	119690315	Missense_Mutation	NA	L1966V	0.41
STAD	chr12	119711066	Intron	novel		0.16
STAD	chr12	119700763	Missense_Mutation	rs749992069	R1827C	0.29
STAD	chr12	119714298	Missense_Mutation	rs763529099	N1360S	0.4
STAD	chr12	119857658	Silent	rs377141243	S93S	0.35
STAD	chr12	119857610	Silent	NA	A109A	0.09
STAD	chr12	119752183	Missense_Mutation	NA	S882F	0.36
STAD	chr12	119752233	Silent	rs748612285	H865H	0.21
STAD	chr12	119822948	Missense_Mutation	novel	P328H	0.11
STAD	chr12	119690428	Missense_Mutation	NA	T1928M	0.33
STAD	chr12	119776727	Missense_Mutation	NA	L594R	0.06
STAD	chr12	119704421	Missense_Mutation	NA	P1707H	0.05
STAD	chr12	119735189	Nonsense_Mutation	NA	R1001*	0.38
STAD	chr12	119690285	Frame_Shift_Del	novel	*L1976Wfs36**	0.13
STAD	chr12	119834119	Missense_Mutation	NA	V209A	0.05
STAD	chr12	119721368	Missense_Mutation	rs773906531	R1183W	0.36
STAD	chr12	119803382	Silent	NA	P373P	0.23
STAD	chr12	119718326	Missense_Mutation	rs540727841	R1321W	0.09
STAD	chr12	119718283	Missense_Mutation	rs779515686	P1335L	0.18
STAD	chr12	119714310	Missense_Mutation	rs774914678	R1356H	0.36
STAD	chr12	119704393	Silent	rs780981739	N1716N	0.13
STAD	chr12	119704443	Missense_Mutation	NA	L1700F	0.35
STAD	chr12	119784950	Intron	novel		0.67
THCA	chr12	119825290	Missense_Mutation	NA	G278S	0.07
UCEC	chr12	119690404	Missense_Mutation	NA	R1936H	0.54
UCEC	chr12	119713493	Silent	NA	L1446L	0.44
UCEC	chr12	119834111	Missense_Mutation	rs181241999	V212I	0.33
UCEC	chr12	119712616	Silent	NA	S1511S	0.47
UCEC	chr12	119712231	Nonsense_Mutation	NA	E1559*	0.32
UCEC	chr12	119713607	Missense_Mutation	NA	P1408T	0.27
UCEC	chr12	119718840	Nonsense_Mutation	NA	E1246*	0.33
UCEC	chr12	119701874	Missense_Mutation	rs565055860	D1755N	0.3
UCEC	chr12	119735158	Splice_Site	NA	X1010_splice	0.3
UCEC	chr12	119767176	Missense_Mutation	rs746443265	E697K	0.32
UCEC	chr12	119803316	Silent	NA	S395S	0.28
UCEC	chr12	119825201	Silent	NA	T307T	0.17
UCEC	chr12	119685842	3'UTR	novel		0.39
UCEC	chr12	119687595	3'UTR	novel		0.29
UCEC	chr12	119758630	Missense_Mutation	novel	K789T	0.46
UCEC	chr12	119776806	Missense_Mutation	novel	M568L	0.24
UCEC	chr12	119832832	Missense_Mutation	rs765352405	R231H	0.36
UCEC	chr12	119857652	Missense_Mutation	novel	K95N	0.41
UCEC	chr12	119712312	Missense_Mutation	novel	H1532N	0.45
UCEC	chr12	119686863	3'UTR	novel		0.38
UCEC	chr12	119688145	3'UTR	rs761061902		0.33
UCEC	chr12	119701753	Splice_Site	NA	X1763_splice	0.37
UCEC	chr12	119704369	Silent	NA	I1724I	0.35
UCEC	chr12	119832849	Missense_Mutation	NA	E225D	0.37
UCEC	chr12	119687517	3'UTR	novel		0.33
UCEC	chr12	119701889	Missense_Mutation	novel	K1750E	0.56
UCEC	chr12	119770906	Intron	rs576662562		0.39
UCEC	chr12	119701676	Silent	rs776565133	I1788I	0.45
UCEC	chr12	119685866	3'UTR	novel		0.13
UCEC	chr12	119697823	Silent	rs373035941	A1864A	0.42
UCEC	chr12	119772811	Missense_Mutation	NA	D681N	0.09
UCEC	chr12	119686690	3'UTR	novel		0.2
UCEC	chr12	119687317	3'UTR	novel		0.45
UCEC	chr12	119690253	Silent	novel	L1986L	0.25
UCEC	chr12	119776705	Silent	novel	R601R	0.48
UCEC	chr12	119776840	Splice_Region	novel	E556E	0.71
UCEC	chr12	119713260	Missense_Mutation	novel	K1466E	0.39
UCEC	chr12	119713550	Missense_Mutation	rs188731838	R1427C	0.45
UCEC	chr12	119718821	Missense_Mutation	NA	T1252I	0.36
UCEC	chr12	119697662	Missense_Mutation	rs775369737	R1918H	0.33
UCEC	chr12	119697757	Silent	NA	A1886A	0.44
UCEC	chr12	119718728	Missense_Mutation	novel	R1283H	0.36
UCEC	chr12	119700786	Missense_Mutation	NA	R1819H	0.31
UCEC	chr12	119730513	Silent	rs377599267	A1114A	0.42
UCEC	chr12	119687998	3'UTR	novel		0.14
UCEC	chr12	119752100	Missense_Mutation	NA	E910K	0.14
UCEC	chr12	119857645	Missense_Mutation	NA	E98K	0.09
UCEC	chr12	119701651	Nonsense_Mutation	novel	R1797*	0.3
UCEC	chr12	119752076	In_Frame_Del	novel	E917del	0.47
UCEC	chr12	119712607	Silent	rs766351202	A1514A	0.13
UCEC	chr12	119718764	Missense_Mutation	NA	R1271H	0.16
UCEC	chr12	119718744	Missense_Mutation	novel	A1278T	0.4
UCEC	chr12	119803355	Silent	rs777108668	D382D	0.47
UCEC	chr12	119735343	Silent	novel	L949L	0.08
UCEC	chr12	119686932	3'UTR	novel		0.46
UCEC	chr12	119687078	3'UTR	novel		0.64
UCEC	chr12	119735325	Silent	novel	Q955Q	0.51
UCEC	chr12	119730543	Silent	novel	Q1104Q	0.29
UCEC	chr12	119784368	Intron	novel		0.31
UCEC	chr12	119687506	3'UTR	rs758593205		0.26
UCEC	chr12	119783954	Missense_Mutation	novel	R500K	0.38
UCEC	chr12	119832792	Silent	novel	A244A	0.5
UCEC	chr12	119758677	Missense_Mutation	novel	K773N	0.41
UCEC	chr12	119767176	Missense_Mutation	rs746443265	E697K	0.13
UCEC	chr12	119803322	Missense_Mutation	novel	K393N	0.53
UCEC	chr12	119822829	Missense_Mutation	novel	I368V	0.3
UCEC	chr12	119690362	Missense_Mutation	novel	P1950Q	0.43
UCEC	chr12	119686105	3'UTR	novel		0.37
UCEC	chr12	119718335	Missense_Mutation	rs767158335	A1318T	0.38
UCEC	chr12	119721420	Silent	novel	L1165L	0.36
UCEC	chr12	119784401	Intron	novel		0.36
UCEC	chr12	119688170	3'UTR	novel		0.32
UCEC	chr12	119721367	Missense_Mutation	rs770422777	R1183Q	0.32
UCEC	chr12	119688091	3'UTR	rs141113548		0.33
UCEC	chr12	119776389	Missense_Mutation	novel	P619L	0.17
UCEC	chr12	119758649	Missense_Mutation	NA	E783K	0.12
UCEC	chr12	119718407	Missense_Mutation	novel	A1294T	0.39
UCEC	chr12	119775798	Missense_Mutation	novel	E643D	0.39
UCEC	chr12	119757469	Missense_Mutation	novel	A828T	0.21
UCEC	chr12	119704427	Missense_Mutation	novel	A1705D	0.34
UCEC	chr12	119770844	Intron	novel		0.08
UCEC	chr12	119784417	Intron	novel		0.67
UCEC	chr12	119686826	3'UTR	novel		0.46
UCEC	chr12	119712301	Silent	NA	C1535C	0.14
UCEC	chr12	119688197	3'UTR	novel		0.49
UCEC	chr12	119708289	Missense_Mutation	novel	V1659M	0.55
UCEC	chr12	119784290	Intron	novel		0.43
UCEC	chr12	119857645	Missense_Mutation	NA	E98K	0.37
UCEC	chr12	119687546	3'UTR	novel		0.32
UCEC	chr12	119767086	Splice_Site	novel	X726_splice	0.51
UCEC	chr12	119832833	Missense_Mutation	rs545710131	R231C	0.36
UCEC	chr12	119784401	Intron	novel		0.36
UCEC	chr12	119728530	Missense_Mutation	novel	R1146L	0.41
UCEC	chr12	119714311	Missense_Mutation	novel	R1356C	0.42
UCEC	chr12	119770784	Intron	novel		0.29
UCEC	chr12	119701933	Missense_Mutation	novel	S1735N	0.06
UCEC	chr12	119772893	Silent	rs141771302	T653T	0.43
UCEC	chr12	119822825	Missense_Mutation	rs200303267	R369H	0.37
UCEC	chr12	119834093	Missense_Mutation	rs777293258	V218M	0.12
UCEC	chr12	119770903	Intron	NA		0.45
UCEC	chr12	119687462	3'UTR	novel		0.29
UCEC	chr12	119701883	Missense_Mutation	novel	Y1752H	0.1
UCEC	chr12	119688005	3'UTR	novel		0.41
UCEC	chr12	119688195	3'UTR	novel		0.22
UCEC	chr12	119710349	Missense_Mutation	novel	L1616P	0.17
UCEC	chr12	119784913	Intron	novel		0.32
UCEC	chr12	119700779	Silent	rs376170277	D1821D	0.13
UCEC	chr12	119701753	Splice_Site	NA	X1763_splice	0.13
UCEC	chr12	119701875	Silent	rs766838097	I1754I	0.16
UCEC	chr12	119772893	Silent	rs141771302	T653T	0.18
UCEC	chr12	119687259	3'UTR	rs373993254		0.27
UCEC	chr12	119757506	Missense_Mutation	NA	Q815H	0.55
UCEC	chr12	119772883	Missense_Mutation	rs778060632	E657K	0.3
UCEC	chr12	119784880	Intron	novel		0.43
UCEC	chr12	119687460	3'UTR	novel		0.42
UCEC	chr12	119784401	Intron	novel		0.5
UCEC	chr12	119697823	Silent	rs373035941	A1864A	0.46
UCEC	chr12	119688036	3'UTR	novel		0.33
UCEC	chr12	119686161	3'UTR	novel		0.2
UCEC	chr12	119714214	Missense_Mutation	novel	Q1388R	0.44
UCEC	chr12	119784890	Intron	novel		0.48
UCEC	chr12	119688139	3'UTR	rs567838142		0.36
UCEC	chr12	119742455	Missense_Mutation	novel	D930Y	0.31
UCEC	chr12	119850263	Frame_Shift_Ins	rs763954129	E143*	0.36
UCEC	chr12	119688216	3'UTR	novel		0.28
UCEC	chr12	119690291	Missense_Mutation	novel	R1974C	0.2
UCEC	chr12	119734236	Frame_Shift_Del	novel	*G1051Vfs43**	0.35
UCEC	chr12	119686862	3'UTR	novel		0.3
UCEC	chr12	119776752	Missense_Mutation	novel	E586K	0.36
UCEC	chr12	119832774	Missense_Mutation	novel	K250N	0.44
UCEC	chr12	119708204	Missense_Mutation	NA	G1687D	0.37
UCEC	chr12	119803236	Missense_Mutation	NA	S422N	0.45
UCEC	chr12	119688159	3'UTR	novel		0.47
UCEC	chr12	119757506	Missense_Mutation	NA	Q815H	0.07
UCEC	chr12	119857645	Missense_Mutation	NA	E98K	0.3
UCEC	chr12	119687075	3'UTR	novel		0.16
UCEC	chr12	119688145	3'UTR	rs761061902		0.1
UCEC	chr12	119708238	Missense_Mutation	rs373149919	D1676N	0.13
UCEC	chr12	119735227	Missense_Mutation	rs768236318	R988Q	0.07
UCEC	chr12	119784400	Intron	NA		0.86
UCEC	chr12	119784400	Intron	NA		0.58
UCEC	chr12	119686627	3'UTR	novel		0.5
UCEC	chr12	119686734	3'UTR	rs146454606		0.24
UCEC	chr12	119690237	Missense_Mutation	novel	R1992W	0.45
UCEC	chr12	119690382	Silent	novel	P1943P	0.33
UCEC	chr12	119752232	Missense_Mutation	novel	E866K	0.24
UCEC	chr12	119772830	Missense_Mutation	novel	E674D	0.11
UCEC	chr12	119718708	Missense_Mutation	novel	R1290W	0.34
UCEC	chr12	119784400	Intron	NA		0.77
UCEC	chr12	119714275	Missense_Mutation	NA	G1368R	0.35
UCEC	chr12	119757506	Missense_Mutation	NA	Q815H	0.19
UCEC	chr12	119734178	Silent	rs562976687	T1070T	0.39
UCEC	chr12	119685917	3'UTR	novel		0.68
UCEC	chr12	119697800	Missense_Mutation	novel	R1872H	0.25
UCEC	chr12	119720551	Missense_Mutation	novel	G1214D	0.27
UCEC	chr12	119832811	Missense_Mutation	novel	V238A	0.31
UCEC	chr12	119822953	Silent	NA	D326D	0.13
UCEC	chr12	119712192	Missense_Mutation	novel	A1572T	0.49
UCEC	chr12	119710334	Missense_Mutation	NA	N1621S	0.77
UCEC	chr12	119713206	Nonsense_Mutation	NA	E1484*	0.42
UCEC	chr12	119735357	Missense_Mutation	NA	V945I	0.18
UCEC	chr12	119690332	Missense_Mutation	novel	R1960H	0.28
UCEC	chr12	119712615	Missense_Mutation	NA	E1512K	0.32
UCEC	chr12	119776821	Nonsense_Mutation	NA	E563*	0.36
UCEC	chr12	119720559	Missense_Mutation	novel	K1211N	0.36
UCEC	chr12	119700793	Missense_Mutation	rs771155127	R1817C	0.12
UCEC	chr12	119734288	Missense_Mutation	novel	D1034N	0.16
UCEC	chr12	119735267	Missense_Mutation	novel	D975N	0.04
UCEC	chr12	119761031	Missense_Mutation	NA	D735Y	0.18
UCEC	chr12	119770907	Intron	rs747535498		0.24
UCEC	chr12	119776752	Missense_Mutation	novel	E586K	0.14
UCEC	chr12	119784517	Intron	novel		0.26
UCEC	chr12	119822833	Silent	novel	N366N	0.18
UCEC	chr12	119822972	Missense_Mutation	rs766974570	R320Q	0.2
UCEC	chr12	119869067	Silent	rs775067327	V77V	0.18
UCEC	chr12	119713614	Silent	rs762518727	T1405T	0.19
UCEC	chr12	119730510	Silent	novel	E1115E	0.36
UCEC	chr12	119772864	Missense_Mutation	NA	R663H	0.55
UCEC	chr12	119697772	Silent	NA	G1881G	0.26
UCEC	chr12	119757483	Missense_Mutation	NA	A823D	0.14
UCEC	chr12	119784401	Intron	novel		0.3
UCEC	chr12	119784936	Intron	novel		0.24
UCEC	chr12	119687439	3'UTR	novel		0.68
UCEC	chr12	119730597	Silent	novel	R1086R	0.27
UCEC	chr12	119687088	3'UTR	novel		0.37
UCEC	chr12	119690312	Missense_Mutation	NA	R1967C	0.49
UCEC	chr12	119698037	Silent	novel	L1839L	0.44
UCEC	chr12	119714325	Missense_Mutation	rs753655957	R1351Q	0.26
UCEC	chr12	119718716	Missense_Mutation	NA	R1287Q	0.38
UCEC	chr12	119730594	Silent	novel	Q1087Q	0.34
UCEC	chr12	119832793	Missense_Mutation	rs140764450	A244V	0.37
UCEC	chr12	119690448	Silent	novel	P1921P	0.06
UCEC	chr12	119752114	Missense_Mutation	novel	R905H	0.41
UCEC	chr12	119711073	Intron	novel		0.15
UCS	chr12	119752207	Missense_Mutation	rs553305582	R874H	0.55
UCS	chr12	119857645	Missense_Mutation	NA	E98K	0.32

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
BRCA	DEL	0.1611	6.3933e-07
CHOL	DEL	0.1944	0.067545
HNSC	DEL	0.0536	0.22646
LUAD	DEL	0.1415	0.0059643
LUSC	DEL	0.1118	0.038823
PAAD	DEL	0.1793	0.0030251
PRAD	AMP	0.0569	0.016187
SKCM	DEL	0.1826	0.00079981

Survival Analysis

Cancer	P-value	Q-value
KIRC	0.002	Kaplan-Meier Survival Analysis
MESO	0.0001	Kaplan-Meier Survival Analysis
ACC	0.00052	Kaplan-Meier Survival Analysis
SKCM	0.0023	Kaplan-Meier Survival Analysis
PRAD	0.036	Kaplan-Meier Survival Analysis
BRCA	0.039	Kaplan-Meier Survival Analysis
PAAD	0.0023	Kaplan-Meier Survival Analysis
UCEC	0.0027	Kaplan-Meier Survival Analysis
LIHC	0.0001	Kaplan-Meier Survival Analysis
LUAD	0.0091	Kaplan-Meier Survival Analysis
UVM	0.0095	Kaplan-Meier Survival Analysis

Drugs

EuRBPDB

Description

RBPome

Expression

Transcripts

Gene Model

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

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Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742